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chr7:122,401,546-125,268,789

Best TWAS P=7.03e-108 · Best GWAS P=3.38e-122 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	IQUB	0.13	0.06	blup	398	0.11	1.4e-13	10.70	-11.4	2.9e-30	-0.24	1.00	0.00	FALSE
2	GTEx	Esophagus Mucosa	RP11-390E23.6	0.06	0.03	enet	14	0.07	2.9e-05	0.69	7.0	3.4e-12	-0.04	0.33	0.03	FALSE
3	GTEx	Lung	WASL	0.10	0.03	lasso	5	0.02	1.5e-02	-15.57	-14.9	6.7e-50	-0.16	0.68	0.02	TRUE
4	GTEx	Pituitary	RP11-390E23.6	0.19	0.03	lasso	10	0.00	2.6e-01	3.09	-6.5	6.9e-11	-0.41	0.06	0.21	FALSE
5	GTEx	Spleen	POT1	0.25	0.16	lasso	3	0.10	1.4e-03	5.29	5.4	7.7e-08	0.02	0.05	0.89	FALSE
6	GTEx	Thyroid	RP11-390E23.6	0.10	0.04	lasso	4	0.07	4.9e-06	0.36	-9.8	1.4e-22	-0.47	0.51	0.43	FALSE
7	YFS	Blood	WASL	0.03	0.03	lasso	8	0.03	5.6e-09	16.73	-14.9	6.4e-50	-0.41	1.00	0.00	FALSE
8	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	POT1	0.03	0.03	blup	67	0.02	7.3e-03	5.52	5.4	5.6e-08	0.03	0.03	0.89	TRUE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	HYAL4	0.02	0.01	blup	37	0.01	1.5e-03	9.25	9.3	1.5e-20	0.69	0.04	0.72	TRUE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	HYAL4	0.14	0.06	blup	37	0.06	1.9e-04	9.28	11.7	1.5e-31	0.65	0.23	0.24	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IQUB	0.03	0.01	blup	53	0.02	4.9e-03	10.28	-7.4	1.8e-13	-0.31	0.28	0.02	TRUE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LMOD2	0.04	0.01	blup	38	0.02	7.1e-03	-15.54	14.6	2.5e-48	0.31	0.14	0.11	TRUE
13	The Cancer Genome Atlas	Lung Adenocarcinoma	HYAL4	0.05	0.03	lasso	5	0.03	6.6e-05	23.04	22.1	7.0e-108	0.96	0.00	0.98	TRUE
14	The Cancer Genome Atlas	Stomach Adenocarcinoma	HYAL4	0.07	0.06	lasso	3	0.05	1.1e-04	9.26	10.0	2.0e-23	0.68	0.08	0.73	TRUE
15	The Cancer Genome Atlas	Thyroid Carcinoma	IQUB	0.09	0.11	lasso	3	0.10	1.6e-09	10.84	-10.7	7.4e-27	-0.36	1.00	0.00	TRUE