TWAS hub - WASL

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Lung	0.101	0.0348	7.6e-05	0.035	NA	0.013	NA	0.018	1.0e-03	NA	3.2e-02	NA	1.5e-02
2	GTEx	Skin Sun Exposed Lower leg	0.068	0.0250	1.5e-04	0.007	NA	0.031	NA	0.012	8.6e-02	NA	1.3e-03	NA	3.0e-02
3	YFS	Blood	0.031	0.0097	9.1e-07	0.026	0.022	0.025	0.021	0.026	4.6e-09	8.8e-08	9.6e-09	1.2e-07	5.6e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Blood Platelet Count	13.3	154.5	222.0	-14.9	-4.4	-14.9
Pulse rate, automated reading	7.5	24.1	51.8	-7.2	-4.2	-1.5
Medication for hormone replacement therapy	5.2	5.8	10.6	3.3	2.6	0.4
Handedness (chirality/laterality): Left-handed	4.7	5.7	13.6	1.8	3.7	0.4
Schizophrenia (2014)	4.4	9.6	15.3	3.9	2.1	3.0
Time employed in main current job	4.1	4.7	7.3	-2.5	-2.7	-0.6
Illnesses of mother	4.0	4.9	8.9	-2.2	-3.0	0.8
Alcohol drinker status: Previous	4.0	4.6	6.6	2.6	1.7	2.1
High blood pressure (mother)	3.7	5.2	9.0	3.0	2.5	-0.5
Systolic Blood Pressure	3.6	18.3	30.2	5.5	4.1	2.8
Medication: Lisinopril	3.5	4.6	10.5	3.2	1.5	-0.9
Medication for cholesterol	3.2	4.9	7.8	-2.8	-2.6	0.2
Eye problems/disorders: Cataract	3.1	3.6	6.0	0.1	-2.2	2.4
Smoking status: Previous	3.0	4.4	7.0	-2.6	-0.8	-2.4
Medication: Aspirin	2.9	3.8	8.6	1.6	2.9	0.3
Bipolar Disorder or Schizophrenia	2.7	6.5	11.5	3.4	1.4	2.5
Age at First Birth	2.7	3.9	6.0	-2.5	-1.8	-1.5
Mouth/teeth dental problems	2.7	4.1	5.5	2.2	1.4	2.3
Schizophrenia (2018)	2.6	5.4	8.1	2.8	1.2	2.6
Mouth/teeth dental problems: Loose teeth	2.6	3.1	6.2	1.7	2.5	0.3
Medication: Paracetamol	2.5	4.1	5.0	-1.8	-2.2	2.0
Angina (self-reported)	2.5	3.2	6.9	1.4	0.9	2.6
Pulse rate	2.4	4.0	8.8	-3.0	-1.8	0.2
Medication: Gliclazide	2.4	2.8	3.8	1.8	2.0	-1.0
Cardiovascular Disease	2.3	7.6	13.2	3.6	3.1	0.5
Number of full brothers	2.3	2.9	5.2	1.8	-0.2	2.3
Medication: Blood pressure	2.3	4.1	6.9	2.6	2.2	0.5
Medication: Aspirin	2.3	3.0	6.3	1.4	2.5	0.7
Mother’s age at death	2.2	2.7	5.9	-2.4	-0.4	-1.5
Lupus	2.1	3.1	7.7	-1.3	-0.0	-2.8
Angina	2.1	2.8	5.4	1.2	1.2	2.3
Father’s age at death	2.1	2.8	6.6	-1.1	-0.8	-2.6
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.3	4.2	1.8	2.0	1.7
Happiness	2.1	2.6	5.2	1.6	2.3	0.3
Guilty feelings	2.1	3.2	6.8	0.3	2.6	1.6
Bipolar Disorder (2011)	2.0	2.0	2.3	1.3	1.5	1.4
Prospective memory result	2.0	2.4	4.7	0.8	-1.4	-2.2
Birth weight of first child	2.0	3.7	8.8	-3.0	-0.7	-1.3
Illnesses of father: Heart disease	2.0	2.8	6.5	0.9	2.5	-1.0
Ever used hormone-replacement therapy (HRT)	1.9	2.5	6.5	0.3	0.9	-2.5
Multivitamins +/- minerals	1.9	2.4	3.5	1.9	1.5	1.2
Impedance of arm (left)	1.9	8.7	12.7	-3.6	-3.3	-1.6
Chronic bronchitis/emphysema (mother)	1.9	2.2	3.5	1.7	1.9	-0.4
Alcohol drinker status: Never	1.9	2.2	5.2	-1.1	-0.4	-2.3
Severe depression (siblings)	1.8	2.0	3.3	0.9	1.4	1.8
Chronic bronchitis/emphysema (father)	1.8	2.1	5.2	-2.3	0.1	-1.1
Mouth/teeth dental problems: Bleeding gums	1.8	2.3	3.2	-1.8	-1.4	-1.4
Wears glasses or contact lenses	1.8	2.0	2.8	0.8	1.7	1.6
Verbal and Numeric Reasoning (VNR)	1.7	4.2	9.7	-3.1	-0.6	-1.6
HbA1C	1.7	1.8	3.9	1.1	-0.6	2.0
Frequency of depressed mood in last 2 weeks	1.6	2.2	5.8	0.5	0.8	2.4
Pack years adult smoking proportion	1.6	2.5	3.1	1.8	1.2	1.7
Hair/balding pattern: Pattern 2	1.6	2.0	3.5	0.8	1.9	-1.3
Mouth/teeth dental problems: Dentures	1.6	2.6	4.2	-2.1	-1.3	-1.4
Illnesses of father: None of the above (group 1)	1.6	2.0	3.4	-0.7	-1.4	1.9
Medication: Blood pressure	1.6	3.0	4.4	2.0	2.1	-0.7
Supplements: Calcium	1.6	1.8	3.8	-0.5	-2.0	1.1
Townsend deprivation index at recruitment	1.5	2.2	5.7	0.2	-0.8	2.4
Had other major operations	1.5	1.8	2.8	-1.7	0.5	-1.6
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	5.3	-0.6	-0.6	-2.3
Impedance of arm (right)	1.5	7.1	11.0	-3.3	-2.9	-1.4
Illnesses of father: High blood pressure	1.5	1.8	3.0	1.7	1.6	-0.1
Unable to work because of sickness or disability	1.5	1.9	2.9	0.4	-1.6	1.7
Depression (Nagel 2018)	1.4	2.1	4.8	0.3	1.2	2.2
Type 2 Diabetes (T2D) (2018)	1.4	2.7	6.4	0.2	2.5	-1.3
Number of treatments/medications taken	1.4	2.6	4.1	1.8	2.0	0.5
Medication for cholesterol, blood pressure or diabetes	1.4	2.3	3.5	-1.9	-1.8	0.4
Had major operations	1.4	1.7	3.0	0.9	1.7	-1.1
Medication: Bendroflumethiazide	1.4	2.2	4.0	2.0	1.4	0.7
Medication: Paracetamol	1.4	2.2	2.7	-1.2	-1.6	1.6
Ovarian Cancer	1.3	1.8	2.2	-1.5	-1.4	-1.1
High blood pressure	1.3	3.6	5.4	2.1	2.3	1.0
Past tobacco smoking	1.3	2.4	4.4	1.7	-0.3	2.1
Exposure to tobacco smoke outside home	1.3	1.7	2.6	1.3	1.6	0.8
Eye problems/disorders: None of the above	1.3	1.5	3.7	-0.9	0.3	-1.9
Knee pain experienced in last month	1.3	2.0	2.8	1.0	1.7	1.5
Average weekly red wine intake	1.3	2.0	3.9	-2.0	-1.3	0.5
Impedance of whole body	1.3	6.4	10.7	-2.8	-3.3	-1.0
Coronary Artery Disease (CAD)	1.2	1.4	2.5	0.9	1.0	1.6
Supplements: Glucosamine	1.2	1.6	4.5	-2.1	-0.5	0.2
Ever highly irritable/argumentative for 2 days	1.2	1.4	3.3	-0.7	-1.8	0.7
Medication: Allopurinol	1.2	1.5	4.4	0.2	0.4	-2.1
Heart disease (mother)	1.2	1.5	2.3	1.5	1.1	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	2.5	-1.2	-1.6	-0.7
Supplements: Vitamin C	1.2	1.4	3.2	-0.6	-1.8	0.7
Pain type(s) experienced in last month: Hip pain	1.2	1.5	3.6	-1.9	-0.8	0.6
High cholesterol (Self-reported)	1.2	2.1	6.2	-0.2	0.1	-2.5
Vitamin and mineral supplements	1.1	1.5	3.7	-0.7	-0.5	-1.9
Diabetes (father)	1.1	1.3	2.9	-0.5	1.7	-0.9
Loud music exposure frequency	1.1	1.2	2.8	-1.7	0.4	-0.8
Medication: Amlodipine	1.1	1.5	3.0	1.2	1.7	0.1
Neck or shoulder pain in last month	1.1	1.5	2.2	-1.5	-1.5	0.4
Mood swings	1.1	2.0	3.9	0.8	1.2	2.0
Ever taken oral contraceptive pill	1.1	1.3	1.6	1.2	1.3	0.8
Vascular/heart problems diagnosed by doctor	1.1	3.0	4.5	-2.1	-1.9	-0.9
Bipolar Disorder (2018)	1.0	1.5	3.5	1.9	0.7	0.8
Systolic blood pressure, automated reading	1.0	3.0	4.7	1.6	1.3	2.2
Stomach or abdominal pain in last month	1.0	1.3	3.7	0.1	-0.2	1.9
Hearing difficulty/problems with background noise	1.0	1.6	4.1	0.1	0.8	2.0
Pain all over the body in last month	1.0	1.1	2.4	0.3	0.8	1.6
Medication: Simvastatin	1.0	1.5	2.7	0.1	1.7	-1.3
Depression (self-reported)	1.0	1.2	1.8	0.8	1.3	1.2
Pulse wave Arterial Stiffness index	1.0	1.1	3.1	-0.2	-1.8	-0.4
Hypertension (Self-reported)	1.0	2.8	4.2	1.9	2.0	0.8
Back pain experienced in last month	1.0	1.5	2.2	1.5	-0.4	1.4
Number of self-reported non-cancer illnesses	1.0	1.8	3.8	1.2	1.9	-0.2
Ever smoked	1.0	1.7	3.4	-0.1	1.9	-1.3
Age started oral contraceptive pill	1.0	1.2	1.5	-1.2	1.1	-1.0
Cholesterol lowering medication	1.0	1.5	2.6	0.3	1.4	-1.6
Mean Putamen Volume	0.9	1.0	2.0	0.9	0.4	1.4
Hypothyroidism (self reported)	0.9	2.0	6.0	-0.3	-0.0	2.4
Supplements: Zinc	0.9	1.0	2.2	0.8	-1.5	0.4
Current tobacco smoking	0.9	1.5	1.9	1.4	1.4	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	2.7	0.2	1.0	1.6
Qualifications: CSEs or equivalent	0.9	1.2	2.7	1.6	1.0	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	1.4	1.2	0.8	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	2.3	-1.5	-1.0	-0.6
Pulse wave peak to peak time	0.9	1.0	2.7	0.2	1.6	0.5
Shortness of breath walking on level ground	0.9	1.0	1.7	1.3	1.2	0.0
Chest pain or discomfort	0.9	1.4	3.9	0.3	-0.4	2.0
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	2.0	1.4	1.0	0.1
Smoking status: Current	0.9	1.4	1.9	1.4	1.2	0.8
Number of operations (self-reported)	0.9	1.3	1.6	1.2	1.2	-1.0
Diastolic blood pressure, automated reading	0.9	2.7	6.0	1.3	0.8	2.4
Ever depressed for a whole week	0.9	1.1	1.5	1.2	0.9	1.1
Pack years of smoking	0.9	1.3	1.4	1.2	1.0	1.2
Worry (Nagel 2018)	0.8	1.7	4.2	-0.7	-0.6	2.0
Crohns Disease (2017)	0.8	1.7	3.3	-1.1	-0.7	1.8
Crohns Disease (2012)	0.8	1.2	1.5	-1.2	-1.2	0.9
Ulcerative Colitis	0.8	1.2	1.7	1.3	1.0	1.0
Heel T-Score	0.8	6.5	18.2	0.5	-1.0	4.3
Neuroticism	0.8	1.8	5.4	0.0	0.2	2.3
Medication: Atenolol	0.8	1.0	1.3	1.0	0.8	1.1
Alcohol usually taken with meals	0.8	1.4	2.6	-1.6	0.2	-1.2
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	1.9	-0.2	1.0	1.4
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.6	0.5	1.6	0.6
Medication: Lansoprazole	0.8	0.9	2.1	0.7	1.4	-0.4
Headache pain in last month	0.8	1.4	2.8	0.9	0.9	1.7
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	2.8	-1.1	-0.6	1.7
Family relationship satisfaction	0.8	0.9	2.2	0.5	1.5	-0.6
Miserableness	0.8	1.3	3.7	0.4	0.1	1.9
Pain experienced in last month	0.8	1.3	3.8	-0.2	0.1	-2.0
Alzheimer’s Disease (in father)	0.7	0.8	0.9	0.8	0.9	-0.9
Primary Biliary Cirrhosis	0.7	1.0	1.5	1.2	0.9	-0.9
Relative age of first facial hair	0.7	1.4	2.6	1.6	-0.5	1.1
Maternal smoking around birth	0.7	1.0	2.6	1.6	0.6	-0.1
Neuroticism score	0.7	1.4	3.7	0.0	0.7	1.9
Falls in the last year	0.7	0.9	1.4	-0.2	1.2	1.2
Breastfed as a baby	0.7	0.9	1.8	-0.7	-1.4	0.6
Hair/balding pattern: Pattern 4	0.7	1.6	2.8	0.2	-1.4	1.7
Worry too long after embarrassment	0.7	1.1	2.5	0.3	1.6	0.9
Alcohol intake frequency.	0.7	1.6	2.9	1.7	1.4	0.3
Illnesses of siblings: Diabetes	0.7	0.8	2.2	-0.5	-0.4	1.5
Friendships satisfaction	0.7	0.9	2.7	-0.1	0.0	-1.7
Average weekly champagne plus white wine intake	0.7	0.9	2.2	-1.5	0.4	-0.7
Commuting to job workplace: Cycle	0.7	0.9	2.3	0.2	-0.4	1.5
Intelligence (Savage-Jansen 2018)	0.6	1.8	4.1	-2.0	0.0	-1.2
Neuroticism (Nagel 2018)	0.6	1.4	2.1	0.3	1.4	1.4
Schizophrenia vs Biploar Disorder	0.6	0.8	1.5	0.5	0.8	1.2
Irritable Bowel Disease (IBD)	0.6	1.5	4.5	-0.2	-0.0	2.1
Breast Cancer	0.6	1.5	4.4	-0.2	0.1	-2.1
Prostate Cancer	0.6	0.8	2.0	0.7	1.4	-0.0
Fasting Glucose	0.6	0.7	1.3	1.1	0.8	0.5
Sensitivity / hurt feelings	0.6	1.0	2.2	0.5	1.5	0.7
Impedance of leg (right)	0.6	3.1	7.6	-1.2	-2.8	-0.6
Trunk fat percentage	0.6	2.2	3.4	-1.8	-1.0	-1.5
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.4	-0.9	0.2	-1.2
Medication: Levothyroxine sodium	0.6	1.0	2.5	-0.2	-0.7	1.6
Impedance of leg (left)	0.6	2.9	6.8	-1.3	-2.6	-0.0
Qualifications: None of the above	0.6	1.3	3.2	-0.1	-1.8	0.8
Fluid intelligence score	0.6	1.3	1.8	-1.4	0.8	-1.1
Suffer from ‘nerves’	0.6	0.9	2.3	-0.6	-0.2	1.5
Age at last live birth	0.6	0.9	2.3	0.1	-0.6	1.5
Commuting to job workplace: Walk	0.6	0.6	1.8	0.3	1.4	0.2
Osteoporosis (self-reported)	0.6	0.7	1.1	-0.7	-0.8	-1.1
Commuting to job workplace: Public transport	0.6	0.7	1.9	-1.4	-0.3	0.5
Average weekly beer plus cider intake	0.6	0.9	1.6	0.4	-1.2	-1.0
Myopia	0.6	0.8	1.7	-1.3	-0.3	-0.8
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.7	0.0	-0.4	1.3
Number of incorrect matches in round	0.5	0.9	1.4	-1.1	-1.2	-0.0
Allergy	0.5	1.2	2.6	1.0	1.6	0.0
Worrier / anxious feelings	0.5	0.9	1.7	-1.3	-0.4	0.9
Qualifications: A levels/AS levels or equivalent	0.5	1.2	3.4	0.1	1.8	0.4
Tense / ‘highly strung’	0.5	0.8	1.2	-0.7	-0.9	1.1
Glaucoma (self-reported)	0.5	0.6	1.5	0.1	0.4	-1.2
Arm fat-free mass (right)	0.5	2.7	4.1	2.0	2.0	0.2
Wheeze or whistling in the chest in last year	0.5	0.9	1.0	1.0	0.9	0.9
Medication for pain relief, constipation, heartburn	0.5	0.8	1.6	0.4	-0.8	-1.3
Medication: Ibuprofen	0.5	0.6	1.6	0.2	1.3	0.3
Medication: Omeprazole	0.5	0.6	1.0	0.7	0.7	-1.0
Medication: Seretide 50 evohaler	0.5	0.6	0.7	0.5	-0.9	0.9
Arm predicted mass (right)	0.5	2.5	3.9	2.0	1.8	0.3
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.5	-1.2	0.3	-0.2
Breast cancer (self-reported)	0.5	0.5	1.2	-0.6	1.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	2.8	-0.4	-1.7	-0.6
Financial situation satisfaction	0.5	0.6	1.1	-1.1	0.1	0.9
Arm fat-free mass (left)	0.5	2.8	5.1	1.8	2.2	0.2
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.1	0.8	1.1	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	0.8	0.8	0.5	-0.9
Arm predicted mass (left)	0.5	2.5	4.0	1.8	2.0	0.4
Alzheimer’s Disease (in mother)	0.4	0.4	0.6	0.8	0.5	0.7
Ulcerative Colitis (UC)	0.4	0.7	1.0	0.6	0.9	1.0
Height	0.4	7.0	11.8	-3.0	-3.4	-0.2
Lung FEV1/FVC ratio	0.4	1.9	4.7	2.2	0.7	0.8
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.0	-0.4	0.6	1.0
Medication: Metformin	0.4	0.5	1.0	-0.4	1.0	0.6
Trunk fat-free mass	0.4	2.5	3.8	1.9	1.9	0.5
Noisy workplace	0.4	0.5	0.9	-0.6	-0.5	-0.9
Medication: Cholesterol lowering	0.4	0.7	1.2	0.4	1.1	-0.8
Trunk predicted mass	0.4	2.5	3.7	1.9	1.9	0.5
Pulse wave reflection index	0.4	0.5	1.0	1.0	-0.7	-0.1
Gout (self-reported)	0.4	0.6	1.7	-0.2	-0.1	-1.3
Body fat percentage	0.4	1.7	2.2	-1.5	-0.8	-1.5
Number of children fathered	0.4	0.5	0.9	-1.0	0.5	0.5
Age at first live birth	0.4	0.7	1.3	-0.8	-1.1	0.3
Qualifications: College or University degree	0.4	1.2	2.0	-1.2	1.4	-0.3
Mean time to correctly identify matches	0.4	0.8	2.5	-1.6	0.1	-0.2
Number of full sisters	0.4	0.5	0.9	-0.1	-0.7	-0.9
Overall health rating	0.4	0.8	1.2	1.1	1.0	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	0.7	-0.5	-0.9	0.7
Whole body fat-free mass	0.4	2.4	3.6	1.8	1.9	0.5
Ever had bowel cancer screening	0.4	0.4	1.0	0.0	0.5	-1.0
Diabetes diagnosed by doctor	0.4	0.6	1.4	-0.6	1.2	-0.1
Qualifications: nursing, teaching	0.4	0.6	1.2	0.5	1.1	-0.7
Osteoarthritis (self-reported)	0.4	0.6	1.6	-1.3	-0.1	-0.3
Whole body water mass	0.4	2.2	3.6	1.7	1.9	0.3
Supplements: Fish oil (including cod liver oil)	0.4	0.5	0.8	-0.8	0.1	-0.9
Heart disease (siblings)	0.4	0.5	0.7	-0.9	-0.3	-0.8
Depressed Affect (Nagel 2018)	0.3	0.7	1.0	0.5	0.9	1.0
Alzheimer’s Disease (including proxy)	0.3	0.5	0.6	0.8	0.7	-0.6
Major Depression (MDD)	0.3	0.4	0.6	-0.7	-0.8	0.3
Body Mass Index (BMI) (2010)	0.3	0.4	0.7	0.8	0.7	0.2
LDL Cholesterol	0.3	0.5	1.0	-0.3	-1.0	0.6
Neuroticism (2016)	0.3	0.4	0.9	0.3	0.3	0.9
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.6	0.1	-0.6	0.8
Blood White Count	0.3	2.3	4.1	-2.0	-1.6	-0.0
BMI	0.3	2.0	3.6	-0.5	1.4	-1.9
Chronotype (morning person)	0.3	0.8	1.3	0.6	-0.8	1.2
Hearing difficulty/problems: Yes	0.3	0.4	0.8	-0.4	-0.4	0.9
Medication: Co-codamol	0.3	0.4	0.5	-0.4	0.7	-0.7
Diabetes (mother)	0.3	0.3	0.6	0.5	0.8	-0.4
Leg fat-free mass (left)	0.3	1.5	2.9	1.2	1.7	0.1
Hand grip strength (right)	0.3	0.7	2.0	0.1	-1.4	-0.5
Fed-up feelings	0.3	0.6	1.5	0.3	0.2	1.2
Relative age voice broke	0.3	0.5	1.2	1.1	0.3	0.4
Age when periods started (menarche)	0.3	0.7	1.5	-0.1	-1.2	-0.7
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	0.8	-0.4	0.9	0.4
Leg predicted mass (left)	0.3	1.4	2.6	1.2	1.6	0.1
Trunk fat mass	0.3	1.3	2.0	-1.3	-0.5	-1.4
Waist circumference	0.3	1.1	1.9	-0.9	0.8	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	0.9	-0.0	0.6	1.0
Had menopause	0.3	0.3	0.6	-0.5	0.3	-0.8
Diabetes (self-reported)	0.3	0.4	0.8	-0.7	0.9	-0.0
Arm fat percentage (right)	0.3	1.1	2.1	-1.1	0.1	-1.4
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	1.3	-0.6	-1.1	-1.1
Exposure to tobacco smoke at home	0.3	0.3	0.7	-0.2	-0.8	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.8	-0.9	0.0	0.8
Qualifications: O levels/GCSEs or equivalent	0.3	0.6	1.5	0.0	1.2	0.4
Birth weight	0.3	0.6	1.1	-0.2	0.8	1.0
High blood pressure (siblings)	0.3	0.4	1.1	-0.4	-0.2	-1.1
Comparative body size at age 10	0.3	0.9	2.3	0.5	-0.3	1.5
Health satisfaction	0.3	0.4	0.7	-0.0	0.7	-0.9
Migraine (self-reported)	0.3	0.4	0.5	-0.5	0.6	0.7
Leg pain on walking	0.3	0.4	0.8	0.9	0.4	0.5
Leg fat-free mass (right)	0.3	1.7	3.2	1.3	1.8	0.5
Arm fat percentage (left)	0.3	1.4	2.9	-1.1	-0.1	-1.7
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	0.9	-0.5	-0.4	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.7	-0.4	-0.8	-0.3
Leg predicted mass (right)	0.3	1.7	3.1	1.3	1.8	0.5
Eye problems/disorders: Glaucoma	0.3	0.4	0.6	0.6	0.2	-0.8
Basal metabolic rate	0.3	1.8	3.2	1.5	1.8	0.1
Fractured/broken bones in last 5 years	0.3	0.4	0.7	0.7	0.0	-0.8
Reaction Time	0.2	0.3	0.5	-0.5	0.7	0.4
Triglycerides	0.2	0.4	0.7	0.6	0.2	-0.9
Blood Eosinophil Count	0.2	1.2	2.0	-1.4	-1.3	-0.2
Blood Red Count	0.2	1.5	2.3	1.5	1.1	-1.0
Waist Hip Ratio (WHR)	0.2	1.1	2.0	-0.5	1.1	-1.4
Smoking Status	0.2	0.5	0.9	-1.0	-0.1	-0.8
Hand grip strength (left)	0.2	0.4	1.1	0.3	-1.0	0.1
Average weekly spirits intake	0.2	0.2	0.5	-0.3	-0.7	0.3
Ever had hysterectomy (womb removed)	0.2	0.2	0.4	0.2	0.4	0.6
Average weekly fortified wine intake	0.2	0.2	0.5	-0.2	-0.7	0.3
Taking other prescription medications	0.2	0.3	0.6	-0.7	0.5	0.3
Serious illness, injury or assault to yourself	0.2	0.3	0.7	0.3	0.1	0.8
Body mass index (BMI)	0.2	0.9	2.0	0.4	1.4	-0.7
Nervous feelings	0.2	0.3	0.6	-0.2	0.6	0.8
Forced vital capacity (FVC)	0.2	0.6	1.4	-0.3	-1.2	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	0.8	0.9	0.2	0.8
Heart attack	0.2	0.3	0.5	-0.5	-0.2	0.7
Asthma	0.2	0.3	0.9	0.1	-0.9	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	1.2	-0.6	-1.1	-0.3
Arm fat mass (right)	0.2	0.6	1.3	-0.2	0.8	-1.1
Length of working week for main job	0.2	0.2	0.4	0.6	-0.1	-0.6
Peak expiratory flow (PEF)	0.2	0.5	0.8	-0.9	-0.0	-0.8
Leg fat percentage (right)	0.2	0.8	1.7	-0.6	-0.5	-1.3
Whole body fat mass	0.2	0.7	1.5	-0.8	-0.2	-1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	0.7	0.6	-0.2	0.8
Long-standing illness, disability or infirmity	0.2	0.4	0.9	0.4	0.9	0.3
Mineral and other dietary supplements	0.2	0.2	0.4	0.5	-0.7	-0.1
Asthma (self-reported)	0.2	0.4	1.1	0.0	-1.1	0.4
Arm fat mass (left)	0.2	0.7	1.5	-0.3	0.7	-1.2
Hearing aid user	0.2	0.2	0.6	0.7	0.4	0.2
Risk taking	0.2	0.3	0.6	-0.4	0.3	-0.8
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.8	-0.3	-0.1	0.9
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.7	-0.0	-0.8	0.1
HDL Cholesterol	0.1	0.2	0.5	-0.7	-0.5	-0.1
Rheumatoid Arthritis	0.1	0.1	0.2	0.3	0.4	-0.2
Allergy or Eczema	0.1	0.4	0.7	-0.6	-0.4	-0.8
Respiratory disease	0.1	0.1	0.4	0.1	-0.6	0.0
Lung FVC	0.1	0.7	1.5	-0.3	-0.8	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.4	0.6	-0.2	0.6
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.4	-0.5	-0.5	-0.6
Financial difficulties in last 2 years	0.1	0.1	0.2	-0.1	0.5	0.3
Illnesses of siblings	0.1	0.1	0.4	0.3	0.6	0.0
Weight	0.1	0.4	0.7	-0.2	0.6	-0.9
Hip circumference	0.1	0.3	0.3	-0.4	0.5	-0.6
Alcohol intake versus 10 years previously	0.1	0.1	0.3	0.2	-0.5	0.2
Number of live births	0.1	0.1	0.2	-0.3	-0.4	0.1
Standing height	0.1	1.0	2.0	-1.0	-1.4	-0.2
Blood clot in the leg (DVT)	0.1	0.2	0.5	-0.2	-0.7	0.0
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.2	-0.1	-0.1	0.4
Forced vital capacity (FVC), Best measure	0.1	0.5	1.2	-0.2	-1.1	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.1	-0.3	-0.1	-0.4
Leg fat mass (right)	0.1	0.4	1.0	-0.2	0.1	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.2	0.1	-0.2	-0.4
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	0.4	0.4	-0.0
Leg fat percentage (left)	0.1	0.5	0.9	-0.7	-0.4	-0.9
Irritability	0.1	0.2	0.5	0.1	0.1	0.7
Basal cell carcinoma (self-reported)	0.1	0.1	0.2	-0.1	0.4	0.1
Leg fat mass (left)	0.1	0.2	0.6	-0.3	0.2	-0.8
Hair Pigment	0.0	0.9	2.4	-0.6	0.2	-1.6
Tanning	0.0	0.5	0.7	0.8	-0.6	0.6
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.1	0.3	0.2	0.1
Sitting height	0.0	0.1	0.2	-0.4	-0.2	0.4
Medication: Ramipril	0.0	0.0	0.1	-0.2	-0.3	0.1
Hair/balding pattern: Pattern 3	0.0	0.0	0.0	0.0	-0.2	-0.0
Lung cancer (father)	0.0	0.0	0.0	0.1	0.1	-0.1
Emphysema/chronic bronchitis	0.0	0.0	0.1	0.2	-0.3	-0.2
Comparative height size at age 10	0.0	0.1	0.2	0.0	-0.5	0.5
Commuting to job workplace: Car/motor vehicle	0.0	0.1	0.1	0.2	0.2	-0.3
Loneliness, isolation	0.0	0.0	0.0	-0.0	0.2	-0.1
Medication: Atorvastatin	0.0	0.0	0.0	0.2	-0.1	0.0

Hub : Genes

WASL

Models

Trait associations