Hub : Genes

LMOD2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Kidney Renal Clear Cell Carcinoma 0.0369 0.0224 0.0011 0.014 0.015 0.015 NA 0.010 0.0088 0.0071 0.0075 NA 0.022
2 TCGA Brain Lower Grade Glioma 0.0486 0.0378 0.0030 -0.002 0.018 0.017 NA 0.005 0.5600 0.0037 0.0039 NA 0.076

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.4 0.7 1.2 -1.1 0.4
Bipolar Disorder or Schizophrenia 1.3 3.3 6.4 -2.5 0.4
Depressed Affect (Nagel 2018) 0.3 0.6 1.1 0.2 1.1
Depression (Nagel 2018) 1.7 2.5 4.1 1.0 2.0
Intelligence (Savage-Jansen 2018) 0.3 1.0 1.6 1.2 0.7
Neuroticism (Nagel 2018) 0.6 1.4 2.7 0.4 1.6
Schizophrenia (2018) 1.3 2.8 5.5 -2.4 0.2
Schizophrenia vs Biploar Disorder 0.1 0.1 0.1 -0.4 0.2
Worry (Nagel 2018) 1.8 3.7 5.9 1.3 2.4
Alzheimer’s Disease (in mother) 0.1 0.1 0.2 -0.5 0.2
Alzheimer’s Disease (in father) 0.5 0.6 0.6 -0.8 -0.8
Alzheimer’s Disease (including proxy) 0.4 0.6 0.7 -0.8 -0.8
Crohns Disease (2017) 2.6 5.8 6.5 2.3 2.5
Irritable Bowel Disease (IBD) 1.3 3.2 4.7 1.3 2.2
Ulcerative Colitis (UC) 0.1 0.1 0.2 -0.2 0.5
Major Depression (MDD) 0.7 0.9 1.1 1.1 0.8
Reaction Time 0.2 0.4 0.8 0.9 -0.1
Verbal and Numeric Reasoning (VNR) 1.0 2.3 4.5 2.1 0.4
Breast Cancer 0.1 0.2 0.2 0.4 -0.4
Ovarian Cancer 1.0 1.4 2.2 1.5 0.7
Prostate Cancer 0.4 0.6 0.8 -0.9 -0.7
Age at First Birth 1.5 2.2 4.1 2.0 0.5
Bipolar Disorder (2011) 1.2 1.2 2.3 0.1 1.5
Body Mass Index (BMI) (2010) 0.1 0.1 0.2 -0.5 0.2
Coronary Artery Disease (CAD) 0.4 0.5 0.8 0.3 0.9
Crohns Disease (2012) 3.3 5.3 5.5 2.3 2.3
Mean Putamen Volume 0.1 0.2 0.2 -0.5 0.3
Fasting Glucose 0.2 0.3 0.5 -0.7 0.2
HbA1C 1.2 1.3 2.2 -1.5 -0.6
HDL Cholesterol 0.3 0.5 0.7 0.8 0.5
LDL Cholesterol 0.1 0.1 0.2 0.1 0.4
Lupus 1.0 1.5 2.9 0.2 -1.7
Neuroticism (2016) 1.1 1.6 2.7 0.7 1.6
Primary Biliary Cirrhosis 1.4 2.1 2.2 -1.4 -1.5
Rheumatoid Arthritis 0.4 0.5 0.8 -0.5 -0.9
Schizophrenia (2014) 2.3 5.0 10.0 -3.2 -0.0
Triglycerides 0.8 1.3 1.5 -1.1 -1.2
Type 2 Diabetes (T2D) (2012) 0.5 0.5 1.1 0.1 1.0
Ulcerative Colitis 0.2 0.3 0.5 -0.7 0.3
Blood Eosinophil Count 0.1 0.6 0.9 0.9 -0.5
Blood Platelet Count 9.5 110.2 213.2 14.6 2.7
Blood Red Count 0.1 1.4 1.5 -1.2 -1.1
Blood White Count 0.1 0.5 0.5 0.7 -0.7
Heel T-Score 0.8 6.7 12.4 1.0 3.5
BMI 0.1 0.5 0.8 0.4 -0.9
Height 0.3 5.7 8.2 2.9 1.8
Waist Hip Ratio (WHR) 0.1 0.3 0.5 0.7 0.0
Systolic Blood Pressure 1.3 6.6 12.0 -3.5 1.1
Smoking Status 0.4 0.9 1.3 0.7 -1.1
Allergy or Eczema 0.1 0.3 0.5 0.2 -0.7
Cardiovascular Disease 1.2 3.9 7.7 -2.8 0.1
Hypothyroidism (self reported) 0.4 0.8 1.0 0.8 1.0
Respiratory disease 0.0 0.0 0.0 -0.0 0.1
Type 2 Diabetes (T2D) (2018) 0.2 0.4 0.7 -0.2 -0.9
Lung FEV1/FVC ratio 0.7 3.5 5.9 -2.4 -1.1
Lung FVC 0.8 4.3 6.8 -1.3 -2.6
Neuroticism 0.9 2.3 4.0 0.7 2.0
Chronotype (morning person) 0.3 0.7 1.4 -0.1 1.2
Hair Pigment 0.0 0.2 0.4 -0.2 -0.6
Tanning 0.0 0.2 0.4 -0.2 0.6
Hand grip strength (left) 0.1 0.2 0.4 -0.1 0.7
Number of treatments/medications taken 0.4 0.7 1.3 -1.1 0.3
Average weekly spirits intake 0.5 0.6 0.7 0.7 0.8
Sensitivity / hurt feelings 0.3 0.6 1.1 0.1 1.1
Frequency of depressed mood in last 2 weeks 1.0 1.4 2.4 0.6 1.6
Hearing difficulty/problems: Yes 0.9 1.4 2.5 0.5 1.6
Relative age of first facial hair 0.4 0.9 1.1 -0.8 1.1
Other serious medical condition/disability diagnosed by doctor 0.1 0.1 0.1 -0.3 0.3
Ever used hormone-replacement therapy (HRT) 0.9 1.1 2.2 -0.1 -1.5
Ever had hysterectomy (womb removed) 0.1 0.1 0.1 -0.2 0.3
Systolic blood pressure, automated reading 0.9 2.6 5.1 -0.2 2.3
Eye problems/disorders: Diabetes related eye disease 2.1 2.3 3.8 0.8 2.0
Angina 0.3 0.4 0.8 -0.3 0.9
Medication for hormone replacement therapy 6.1 6.8 8.2 -2.9 -2.3
Vitamin and mineral supplements 0.6 0.8 1.6 -0.2 -1.3
Supplements: Zinc 0.4 0.4 0.7 -0.8 -0.3
Medication: Co-codamol 0.2 0.3 0.5 -0.3 -0.7
Medication: Metformin 0.5 0.7 0.8 0.8 0.9
Diabetes (father) 0.7 0.8 1.6 -0.2 -1.3
Diabetes (mother) 0.5 0.6 0.7 -0.8 -0.7
Severe depression (siblings) 0.9 1.0 1.9 0.2 1.4
Pack years adult smoking proportion 0.7 1.0 2.0 -1.4 0.2
Impedance of leg (right) 0.1 0.4 0.8 0.9 -0.0
Leg fat-free mass (left) 0.1 0.4 0.6 -0.8 -0.5
Trunk fat percentage 0.3 1.3 2.4 1.6 -0.5
Hand grip strength (right) 0.0 0.0 0.0 -0.0 0.2
Townsend deprivation index at recruitment 0.2 0.3 0.6 0.1 0.8
Current tobacco smoking 0.8 1.4 1.6 -1.3 -1.1
Average weekly fortified wine intake 0.7 0.8 1.1 0.7 1.1
Maternal smoking around birth 1.2 1.7 2.6 -1.6 -0.9
Fed-up feelings 0.2 0.3 0.6 0.1 0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.2 1.6 0.9 1.3
Relative age voice broke 0.2 0.4 0.7 -0.8 0.0
Taking other prescription medications 1.0 1.6 1.9 1.1 1.4
Age when periods started (menarche) 0.0 0.1 0.2 0.4 0.1
Bilateral oophorectomy (both ovaries removed) 0.1 0.1 0.2 -0.4 -0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.1 0.2 -0.3 0.4
Tinnitus: Yes, but not now, but have in the past 0.0 0.0 0.0 0.0 0.1
Qualifications: CSEs or equivalent 0.8 1.1 1.6 -1.3 -0.8
Serious illness, injury or assault to yourself 1.1 1.3 2.0 0.8 1.4
High blood pressure 0.3 1.0 1.2 -1.1 0.8
Hayfever, allergic rhinitis or eczema 0.2 0.5 0.9 -0.3 -1.0
Multivitamins +/- minerals 0.8 1.0 2.0 -1.4 -0.0
Stomach or abdominal pain in last month 1.4 1.7 3.1 0.6 1.8
Supplements: Glucosamine 3.1 4.0 5.5 2.3 1.6
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 1.2 0.2 -1.1
Medication: Atenolol 0.3 0.4 0.7 -0.4 0.8
Medication: Levothyroxine sodium 0.4 0.7 0.9 0.7 0.9
Sitting height 0.0 0.1 0.1 0.3 0.3
Chronic bronchitis/emphysema (father) 2.9 3.4 6.4 2.5 0.7
High blood pressure (mother) 2.0 2.9 4.3 -2.1 -1.2
Body mass index (BMI) 0.1 0.3 0.5 -0.2 -0.7
Impedance of leg (left) 0.1 0.6 1.2 1.1 0.3
Leg predicted mass (left) 0.1 0.4 0.6 -0.8 -0.4
Trunk fat mass 0.2 0.8 1.3 1.1 -0.5
Waist circumference 0.1 0.3 0.5 0.7 -0.3
Number of incorrect matches in round 0.8 1.3 1.4 1.1 1.2
Past tobacco smoking 0.6 1.2 1.5 -0.9 1.2
Alcohol usually taken with meals 0.5 0.8 1.6 1.2 0.2
Nervous feelings 0.1 0.3 0.3 0.4 0.6
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.1 0.2 -0.2 -0.4
Hearing difficulty/problems with background noise 0.7 1.1 1.8 0.6 1.3
Hair/balding pattern: Pattern 2 0.9 1.2 1.2 -1.1 -1.1
Had menopause 0.1 0.1 0.1 0.4 0.1
Had other major operations 2.9 3.5 6.2 2.5 0.9
Forced vital capacity (FVC) 0.4 1.4 1.9 -0.9 -1.4
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 0.6 -0.8 0.5
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 0.9 0.3 0.9
Qualifications: None of the above 0.1 0.2 0.4 0.4 0.6
Financial difficulties in last 2 years 0.1 0.1 0.2 0.4 -0.1
Mouth/teeth dental problems 0.6 1.0 1.9 -1.4 0.1
Heart attack 0.3 0.4 0.5 0.7 0.6
Allergy 0.1 0.2 0.3 -0.6 0.1
Pain all over the body in last month 0.6 0.6 1.3 0.1 1.1
Diabetes (self-reported) 0.1 0.2 0.4 0.6 0.2
Hayfever/allergic rhinitis (self-reported) 1.4 1.9 3.3 -0.7 -1.8
Medication: Ramipril 1.0 1.3 1.8 0.9 1.4
Medication: Simvastatin 0.0 0.0 0.0 0.0 -0.2
Fluid intelligence score 0.1 0.1 0.2 0.5 0.0
Illnesses of siblings 0.3 0.4 0.6 0.4 0.8
Neuroticism score 1.3 2.6 4.4 0.9 2.1
Weight 0.0 0.1 0.2 0.3 -0.4
Impedance of arm (right) 0.7 3.4 6.8 2.6 0.2
Arm fat percentage (right) 0.2 0.7 0.9 0.7 -0.9
Trunk fat-free mass 0.1 0.7 1.4 -1.2 0.1
Hip circumference 0.0 0.1 0.2 0.4 -0.3
Time employed in main current job 3.5 4.1 5.7 2.4 1.6
Alcohol intake versus 10 years previously 0.2 0.3 0.6 -0.0 0.8
Father’s age at death 1.0 1.4 2.7 -0.2 -1.6
Worrier / anxious feelings 1.5 2.9 3.2 1.6 1.8
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 1.1 -1.0 0.0
Falls in the last year 4.4 6.0 6.6 2.3 2.6
Hair/balding pattern: Pattern 3 0.1 0.1 0.2 0.5 0.2
Number of live births 0.5 0.7 1.0 0.6 1.0
Forced expiratory volume in 1-second (FEV1) 0.5 1.6 2.8 -0.7 -1.7
Pulse rate 4.5 7.6 10.1 3.2 2.3
Happiness 0.7 0.9 1.3 -1.1 -0.7
Noisy workplace 0.1 0.1 0.2 0.4 -0.2
Qualifications: A levels/AS levels or equivalent 0.1 0.3 0.5 0.3 0.7
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.8 1.0 -1.0 -0.8
Mouth/teeth dental problems: Dentures 1.6 2.6 4.2 2.1 1.0
Asthma 0.2 0.4 0.7 0.3 0.8
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 0.3 -0.4 0.5
Medication: Cholesterol lowering 0.0 0.1 0.1 -0.2 -0.3
Depression (self-reported) 0.4 0.5 0.6 -0.8 -0.6
Medication: Lansoprazole 1.3 1.5 1.9 -1.1 -1.4
Prospective memory result 4.3 5.3 6.9 -1.9 -2.6
Lung cancer (father) 0.1 0.1 0.1 0.2 0.3
Illnesses of mother 3.1 3.8 5.3 2.3 1.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.8 2.9 -0.8 -1.7
Pulse wave Arterial Stiffness index 0.2 0.2 0.3 -0.4 -0.6
Impedance of arm (left) 0.8 3.5 6.9 2.6 0.0
Arm fat mass (right) 0.1 0.5 0.9 0.2 -1.0
Trunk predicted mass 0.1 0.7 1.4 -1.2 0.0
Standing height 0.0 0.5 0.8 0.9 0.4
Length of working week for main job 1.1 1.2 1.4 -1.2 -1.0
Exposure to tobacco smoke at home 0.3 0.4 0.5 -0.5 -0.7
Breastfed as a baby 0.8 1.0 1.2 0.9 1.1
Tense / ‘highly strung’ 0.5 0.9 1.1 0.8 1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 0.9 1.2 1.1 0.8
Hair/balding pattern: Pattern 4 0.1 0.3 0.6 -0.1 0.8
Birth weight of first child 4.5 8.2 14.0 3.7 1.6
Peak expiratory flow (PEF) 0.3 0.6 1.2 -0.2 -1.1
Pulse wave reflection index 1.9 2.3 2.4 -1.5 -1.5
Ever highly irritable/argumentative for 2 days 0.2 0.3 0.3 0.4 0.6
Loud music exposure frequency 1.8 1.9 3.7 1.9 0.4
Qualifications: O levels/GCSEs or equivalent 0.0 0.0 0.0 -0.1 0.1
Mouth/teeth dental problems: Bleeding gums 1.1 1.5 2.8 1.7 0.3
Blood clot in the leg (DVT) 2.0 2.5 3.9 -1.1 -2.0
Medication: Paracetamol 3.5 5.8 6.9 2.1 2.6
Headache pain in last month 0.2 0.4 0.7 -0.3 0.8
Medication for cholesterol, blood pressure or diabetes 0.8 1.3 2.6 1.6 0.4
Glaucoma (self-reported) 1.5 1.8 3.0 -0.8 -1.7
Gout (self-reported) 1.4 1.9 3.1 -0.8 -1.8
Hypothyroidism/myxoedema (self-reported) 1.2 2.3 2.5 1.6 1.5
Medication: Amlodipine 0.2 0.3 0.5 -0.7 -0.3
Medication: Ventolin 100micrograms inhaler 2.7 3.5 4.9 1.4 2.2
Birth weight 0.0 0.1 0.1 0.4 0.2
Chronic bronchitis/emphysema (mother) 5.3 6.1 7.1 -2.7 -2.3
High blood pressure (siblings) 0.2 0.3 0.5 0.3 -0.7
Forced vital capacity (FVC), Best measure 0.5 1.8 2.7 -1.0 -1.6
Body fat percentage 0.2 0.9 1.5 1.2 -0.6
Leg fat percentage (right) 0.1 0.4 0.5 0.5 -0.7
Arm fat-free mass (right) 0.2 1.2 2.2 -1.5 -0.5
Exposure to tobacco smoke outside home 1.2 1.6 2.8 -1.7 -0.6
Comparative body size at age 10 0.0 0.1 0.2 -0.3 0.4
Number of full brothers 0.8 1.0 1.8 -1.3 -0.4
Worry too long after embarrassment 0.5 0.9 1.4 0.6 1.2
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 1.0 1.0 -0.2
Wheeze or whistling in the chest in last year 0.3 0.5 1.0 0.3 1.0
Number of children fathered 0.3 0.4 0.7 0.8 0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.3 0.3 -0.4 -0.6
Age at first live birth 0.4 0.8 1.0 0.8 1.0
Pulse wave peak to peak time 0.3 0.3 0.4 0.4 0.6
Health satisfaction 0.9 1.2 1.7 -0.8 -1.3
Shortness of breath walking on level ground 1.7 2.0 2.3 -1.5 -1.3
Qualifications: College or University degree 0.1 0.2 0.3 0.2 -0.6
Eye problems/disorders: None of the above 1.9 2.2 4.4 -0.2 -2.1
Mouth/teeth dental problems: Loose teeth 0.6 0.7 1.4 -1.2 -0.2
Emphysema/chronic bronchitis 0.5 0.6 0.8 0.6 0.9
Medication for pain relief, constipation, heartburn 1.4 2.4 4.0 -0.9 -2.0
Neck or shoulder pain in last month 2.2 3.1 3.7 1.9 1.6
Medication: Blood pressure 1.0 1.7 3.5 -1.9 0.1
Angina (self-reported) 0.5 0.6 1.1 -0.3 1.1
Migraine (self-reported) 0.8 1.0 1.2 1.1 0.9
Medication: Ibuprofen 0.1 0.1 0.2 -0.4 0.3
Medication: Allopurinol 2.2 3.0 4.4 -1.3 -2.1
Medication: Omeprazole 0.6 0.8 0.8 -0.8 -0.9
Medication: Seretide 50 evohaler 0.4 0.5 1.0 0.0 1.0
Mean time to correctly identify matches 0.7 1.4 2.8 1.7 0.2
Heart disease (mother) 1.2 1.4 2.4 -1.6 -0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.4 1.7 1.9 1.2 1.4
Whole body fat mass 0.1 0.5 0.5 0.7 -0.6
Leg fat mass (right) 0.1 0.3 0.5 0.3 -0.7
Arm predicted mass (right) 0.2 1.1 2.1 -1.5 -0.3
Pulse rate, automated reading 8.0 26.0 42.9 6.5 3.0
Alcohol intake frequency. 0.2 0.4 0.8 -0.9 0.3
Comparative height size at age 10 0.0 0.0 0.0 0.1 0.1
Number of full sisters 1.0 1.2 2.0 -0.6 -1.4
Suffer from ‘nerves’ 1.1 1.7 2.0 1.2 1.4
Overall health rating 0.8 1.8 2.1 -1.5 -1.2
Chest pain or discomfort 0.4 0.6 1.2 0.1 1.1
Had major operations 0.6 0.7 1.1 -1.0 -0.5
Age at last live birth 0.3 0.4 0.8 -0.1 0.9
Family relationship satisfaction 0.1 0.1 0.2 0.4 -0.1
Leg pain on walking 0.1 0.2 0.2 -0.4 0.4
Qualifications: NVQ or HND or HNC or equivalent 1.0 1.2 1.7 0.8 1.3
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.3 -0.6 0.2
Illness, injury, bereavement, stress in last 2 years 0.1 0.1 0.1 0.1 -0.4
Medication: Aspirin 2.6 3.5 3.5 -1.9 -1.8
Supplements: Vitamin C 0.9 1.1 1.3 0.9 1.1
Knee pain experienced in last month 1.0 1.5 2.9 0.4 1.7
Hypertension (Self-reported) 0.3 0.8 1.0 -1.0 0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.3 0.5 -0.3 -0.7
Illnesses of father: Heart disease 0.9 1.2 1.4 -1.2 -1.0
Illnesses of siblings: Diabetes 0.7 0.8 1.6 0.2 1.3
Smoking status: Previous 1.2 1.8 3.5 1.9 -0.3
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 0.7 -0.8 -0.2
Whole body fat-free mass 0.1 0.7 1.4 -1.2 -0.1
Leg fat-free mass (right) 0.1 0.3 0.6 -0.8 -0.2
Arm fat percentage (left) 0.2 0.9 1.3 0.6 -1.2
Average weekly red wine intake 1.1 1.6 2.0 1.4 1.1
Handedness (chirality/laterality): Left-handed 0.3 0.4 0.6 -0.3 0.8
Mood swings 0.9 1.7 3.2 0.4 1.8
Loneliness, isolation 0.5 0.7 0.8 0.9 0.8
Long-standing illness, disability or infirmity 0.1 0.1 0.2 -0.2 0.4
Ever had bowel cancer screening 0.4 0.5 0.7 -0.6 -0.8
Diabetes diagnosed by doctor 0.3 0.4 0.7 0.8 0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.9 0.9 1.5 -1.2 -0.5
Friendships satisfaction 1.1 1.4 2.6 -0.5 -1.6
Qualifications: nursing, teaching 0.5 0.7 0.9 -0.7 -0.9
Commuting to job workplace: Walk 0.7 0.8 1.5 -0.3 -1.2
Eye problems/disorders: Cataract 3.5 4.0 6.9 1.1 2.6
Mouth/teeth dental problems: Mouth ulcers 0.1 0.1 0.3 0.2 -0.5
Medication for cholesterol 3.4 5.1 6.3 2.5 2.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 0.6 -0.3 -0.8
Back pain experienced in last month 1.2 1.7 3.4 -1.8 -0.2
Mineral and other dietary supplements 1.1 1.4 1.5 -1.2 -1.2
Breast cancer (self-reported) 1.2 1.4 2.0 1.4 1.0
Asthma (self-reported) 0.3 0.6 1.1 0.4 1.0
Osteoporosis (self-reported) 0.2 0.2 0.5 0.0 -0.7
Osteoarthritis (self-reported) 2.4 3.1 3.7 1.9 1.6
Medication: Aspirin 1.2 1.6 2.0 -1.4 -1.1
Medication: Gliclazide 2.5 2.8 3.7 -1.9 -1.4
Illnesses of father: None of the above (group 1) 1.2 1.4 2.1 0.9 1.5
Smoking status: Current 1.0 1.6 1.7 -1.3 -1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.3 2.7 4.8 -0.8 -2.2
Whole body water mass 0.1 0.7 1.3 -1.2 -0.2
Leg predicted mass (right) 0.1 0.3 0.6 -0.8 -0.2
Arm fat mass (left) 0.1 0.5 1.0 0.1 -1.0
Number of self-reported non-cancer illnesses 0.5 0.9 1.6 -1.3 -0.4
Average weekly champagne plus white wine intake 0.5 0.6 1.1 1.1 0.3
Miserableness 0.2 0.3 0.6 -0.1 0.7
Guilty feelings 0.1 0.2 0.2 -0.4 0.4
Wears glasses or contact lenses 0.1 0.1 0.1 -0.3 0.3
Ever taken oral contraceptive pill 0.5 0.6 1.0 -1.0 -0.5
Hearing aid user 0.5 0.5 0.7 -0.8 -0.6
Mother’s age at death 1.2 1.5 2.9 1.7 -0.3
Financial situation satisfaction 0.7 0.9 1.7 1.3 0.2
Tinnitus: Yes, now most or all of the time 0.6 0.7 1.1 0.4 1.1
Commuting to job workplace: Public transport 1.1 1.3 2.4 1.6 0.3
Eye problems/disorders: Glaucoma 1.8 2.1 3.2 -1.0 -1.8
Medication: Blood pressure 1.4 2.7 3.7 -1.9 -1.3
Pain type(s) experienced in last month: Hip pain 1.1 1.3 1.9 1.4 0.9
Supplements: Fish oil (including cod liver oil) 1.2 1.5 2.0 1.4 1.0
High cholesterol (Self-reported) 0.9 1.6 2.9 -0.5 -1.7
Medication: Bendroflumethiazide 0.5 0.7 1.5 -1.2 0.1
Medication: Paracetamol 2.2 3.4 4.2 1.6 2.0
Medication: Lisinopril 9.3 12.0 17.0 -4.1 -2.7
Medication: Atorvastatin 0.0 0.1 0.1 -0.3 -0.1
Illnesses of father: High blood pressure 1.3 1.6 2.6 -1.6 -0.8
Alcohol drinker status: Never 0.3 0.4 0.5 0.5 -0.7
Ever smoked 0.7 1.2 2.3 -0.3 -1.5
Basal metabolic rate 0.1 0.6 1.1 -1.0 -0.4
Leg fat percentage (left) 0.1 0.3 0.4 0.7 -0.5
Arm fat-free mass (left) 0.2 1.0 1.8 -1.4 -0.4
Number of operations (self-reported) 0.2 0.4 0.5 -0.7 -0.5
Average weekly beer plus cider intake 0.2 0.2 0.3 -0.3 -0.6
Irritability 0.2 0.3 0.5 0.3 0.7
Risk taking 0.2 0.2 0.3 0.5 -0.5
Ever had prostate specific antigen (PSA) test 0.4 0.5 0.8 -0.9 -0.4
Fractured/broken bones in last 5 years 0.2 0.2 0.3 -0.6 -0.4
Age started oral contraceptive pill 0.5 0.6 1.2 1.1 0.0
Diastolic blood pressure, automated reading 0.7 2.0 4.0 -0.1 2.0
Ever depressed for a whole week 0.9 1.1 1.4 -1.2 -0.9
Unable to work because of sickness or disability 0.1 0.1 0.3 0.1 0.5
Commuting to job workplace: Cycle 0.3 0.4 0.6 0.4 0.8
Myopia 0.5 0.7 1.0 1.0 -0.5
Vascular/heart problems diagnosed by doctor 0.4 1.0 1.7 1.3 -0.6
Cholesterol lowering medication 0.3 0.5 0.8 -0.5 -0.9
Medication: Omeprazole (e.g. Zanprol) 0.5 0.7 0.9 -1.0 -0.6
Pain experienced in last month 0.7 1.2 2.3 -0.3 -1.5
Supplements: Calcium 0.5 0.6 0.7 0.7 0.8
Basal cell carcinoma (self-reported) 0.0 0.0 0.1 0.3 -0.0
Heart attack/myocardial infarction (self-reported) 0.2 0.3 0.3 0.6 0.5
Deep venous thrombosis (DVT) (self-reported) 2.5 3.2 4.6 -1.3 -2.1
Heart disease (siblings) 0.5 0.7 1.3 -0.3 -1.1
Alcohol drinker status: Previous 1.5 1.7 3.1 -1.8 0.5
Pack years of smoking 0.4 0.5 1.1 -1.0 0.0
Impedance of whole body 0.4 2.3 4.5 2.1 0.2
Leg fat mass (left) 0.1 0.3 0.3 0.4 -0.6
Arm predicted mass (left) 0.2 1.2 2.2 -1.5 -0.5