TWAS hub - LMOD2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Clear Cell Carcinoma	0.0369	0.0224	0.0011	0.014	0.015	0.015	NA	0.010	0.0088	0.0071	0.0075	NA	0.022
2	TCGA	Brain Lower Grade Glioma	0.0486	0.0378	0.0030	-0.002	0.018	0.017	NA	0.005	0.5600	0.0037	0.0039	NA	0.076

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood Platelet Count	9.5	110.2	213.2	14.6	2.7
Medication: Lisinopril	9.3	12.0	17.0	-4.1	-2.7
Pulse rate, automated reading	8.0	26.0	42.9	6.5	3.0
Medication for hormone replacement therapy	6.1	6.8	8.2	-2.9	-2.3
Chronic bronchitis/emphysema (mother)	5.3	6.1	7.1	-2.7	-2.3
Pulse rate	4.5	7.6	10.1	3.2	2.3
Birth weight of first child	4.5	8.2	14.0	3.7	1.6
Falls in the last year	4.4	6.0	6.6	2.3	2.6
Prospective memory result	4.3	5.3	6.9	-1.9	-2.6
Time employed in main current job	3.5	4.1	5.7	2.4	1.6
Medication: Paracetamol	3.5	5.8	6.9	2.1	2.6
Eye problems/disorders: Cataract	3.5	4.0	6.9	1.1	2.6
Medication for cholesterol	3.4	5.1	6.3	2.5	2.0
Crohns Disease (2012)	3.3	5.3	5.5	2.3	2.3
Supplements: Glucosamine	3.1	4.0	5.5	2.3	1.6
Illnesses of mother	3.1	3.8	5.3	2.3	1.5
Chronic bronchitis/emphysema (father)	2.9	3.4	6.4	2.5	0.7
Had other major operations	2.9	3.5	6.2	2.5	0.9
Medication: Ventolin 100micrograms inhaler	2.7	3.5	4.9	1.4	2.2
Crohns Disease (2017)	2.6	5.8	6.5	2.3	2.5
Medication: Aspirin	2.6	3.5	3.5	-1.9	-1.8
Medication: Gliclazide	2.5	2.8	3.7	-1.9	-1.4
Deep venous thrombosis (DVT) (self-reported)	2.5	3.2	4.6	-1.3	-2.1
Osteoarthritis (self-reported)	2.4	3.1	3.7	1.9	1.6
Schizophrenia (2014)	2.3	5.0	10.0	-3.2	-0.0
Neck or shoulder pain in last month	2.2	3.1	3.7	1.9	1.6
Medication: Allopurinol	2.2	3.0	4.4	-1.3	-2.1
Medication: Paracetamol	2.2	3.4	4.2	1.6	2.0
Eye problems/disorders: Diabetes related eye disease	2.1	2.3	3.8	0.8	2.0
High blood pressure (mother)	2.0	2.9	4.3	-2.1	-1.2
Blood clot in the leg (DVT)	2.0	2.5	3.9	-1.1	-2.0
Pulse wave reflection index	1.9	2.3	2.4	-1.5	-1.5
Eye problems/disorders: None of the above	1.9	2.2	4.4	-0.2	-2.1
Worry (Nagel 2018)	1.8	3.7	5.9	1.3	2.4
Loud music exposure frequency	1.8	1.9	3.7	1.9	0.4
Eye problems/disorders: Glaucoma	1.8	2.1	3.2	-1.0	-1.8
Depression (Nagel 2018)	1.7	2.5	4.1	1.0	2.0
Shortness of breath walking on level ground	1.7	2.0	2.3	-1.5	-1.3
Mouth/teeth dental problems: Dentures	1.6	2.6	4.2	2.1	1.0
Age at First Birth	1.5	2.2	4.1	2.0	0.5
Worrier / anxious feelings	1.5	2.9	3.2	1.6	1.8
Glaucoma (self-reported)	1.5	1.8	3.0	-0.8	-1.7
Alcohol drinker status: Previous	1.5	1.7	3.1	-1.8	0.5
Primary Biliary Cirrhosis	1.4	2.1	2.2	-1.4	-1.5
Stomach or abdominal pain in last month	1.4	1.7	3.1	0.6	1.8
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	3.3	-0.7	-1.8
Gout (self-reported)	1.4	1.9	3.1	-0.8	-1.8
Medication for pain relief, constipation, heartburn	1.4	2.4	4.0	-0.9	-2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	1.9	1.2	1.4
Medication: Blood pressure	1.4	2.7	3.7	-1.9	-1.3
Bipolar Disorder or Schizophrenia	1.3	3.3	6.4	-2.5	0.4
Schizophrenia (2018)	1.3	2.8	5.5	-2.4	0.2
Irritable Bowel Disease (IBD)	1.3	3.2	4.7	1.3	2.2
Systolic Blood Pressure	1.3	6.6	12.0	-3.5	1.1
Neuroticism score	1.3	2.6	4.4	0.9	2.1
Medication: Lansoprazole	1.3	1.5	1.9	-1.1	-1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	4.8	-0.8	-2.2
Illnesses of father: High blood pressure	1.3	1.6	2.6	-1.6	-0.8
Bipolar Disorder (2011)	1.2	1.2	2.3	0.1	1.5
HbA1C	1.2	1.3	2.2	-1.5	-0.6
Cardiovascular Disease	1.2	3.9	7.7	-2.8	0.1
Maternal smoking around birth	1.2	1.7	2.6	-1.6	-0.9
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	2.5	1.6	1.5
Exposure to tobacco smoke outside home	1.2	1.6	2.8	-1.7	-0.6
Heart disease (mother)	1.2	1.4	2.4	-1.6	-0.6
Smoking status: Previous	1.2	1.8	3.5	1.9	-0.3
Back pain experienced in last month	1.2	1.7	3.4	-1.8	-0.2
Breast cancer (self-reported)	1.2	1.4	2.0	1.4	1.0
Medication: Aspirin	1.2	1.6	2.0	-1.4	-1.1
Illnesses of father: None of the above (group 1)	1.2	1.4	2.1	0.9	1.5
Mother’s age at death	1.2	1.5	2.9	1.7	-0.3
Supplements: Fish oil (including cod liver oil)	1.2	1.5	2.0	1.4	1.0
Neuroticism (2016)	1.1	1.6	2.7	0.7	1.6
Serious illness, injury or assault to yourself	1.1	1.3	2.0	0.8	1.4
Length of working week for main job	1.1	1.2	1.4	-1.2	-1.0
Mouth/teeth dental problems: Bleeding gums	1.1	1.5	2.8	1.7	0.3
Suffer from ‘nerves’	1.1	1.7	2.0	1.2	1.4
Average weekly red wine intake	1.1	1.6	2.0	1.4	1.1
Friendships satisfaction	1.1	1.4	2.6	-0.5	-1.6
Mineral and other dietary supplements	1.1	1.4	1.5	-1.2	-1.2
Commuting to job workplace: Public transport	1.1	1.3	2.4	1.6	0.3
Pain type(s) experienced in last month: Hip pain	1.1	1.3	1.9	1.4	0.9
Verbal and Numeric Reasoning (VNR)	1.0	2.3	4.5	2.1	0.4
Ovarian Cancer	1.0	1.4	2.2	1.5	0.7
Lupus	1.0	1.5	2.9	0.2	-1.7
Frequency of depressed mood in last 2 weeks	1.0	1.4	2.4	0.6	1.6
Taking other prescription medications	1.0	1.6	1.9	1.1	1.4
Medication: Ramipril	1.0	1.3	1.8	0.9	1.4
Father’s age at death	1.0	1.4	2.7	-0.2	-1.6
Medication: Blood pressure	1.0	1.7	3.5	-1.9	0.1
Number of full sisters	1.0	1.2	2.0	-0.6	-1.4
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	1.7	0.8	1.3
Knee pain experienced in last month	1.0	1.5	2.9	0.4	1.7
Smoking status: Current	1.0	1.6	1.7	-1.3	-1.2
Neuroticism	0.9	2.3	4.0	0.7	2.0
Hearing difficulty/problems: Yes	0.9	1.4	2.5	0.5	1.6
Ever used hormone-replacement therapy (HRT)	0.9	1.1	2.2	-0.1	-1.5
Systolic blood pressure, automated reading	0.9	2.6	5.1	-0.2	2.3
Severe depression (siblings)	0.9	1.0	1.9	0.2	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	1.6	0.9	1.3
Hair/balding pattern: Pattern 2	0.9	1.2	1.2	-1.1	-1.1
Health satisfaction	0.9	1.2	1.7	-0.8	-1.3
Supplements: Vitamin C	0.9	1.1	1.3	0.9	1.1
Illnesses of father: Heart disease	0.9	1.2	1.4	-1.2	-1.0
Mood swings	0.9	1.7	3.2	0.4	1.8
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	1.5	-1.2	-0.5
High cholesterol (Self-reported)	0.9	1.6	2.9	-0.5	-1.7
Ever depressed for a whole week	0.9	1.1	1.4	-1.2	-0.9
Triglycerides	0.8	1.3	1.5	-1.1	-1.2
Heel T-Score	0.8	6.7	12.4	1.0	3.5
Lung FVC	0.8	4.3	6.8	-1.3	-2.6
Current tobacco smoking	0.8	1.4	1.6	-1.3	-1.1
Qualifications: CSEs or equivalent	0.8	1.1	1.6	-1.3	-0.8
Multivitamins +/- minerals	0.8	1.0	2.0	-1.4	-0.0
Number of incorrect matches in round	0.8	1.3	1.4	1.1	1.2
Impedance of arm (left)	0.8	3.5	6.9	2.6	0.0
Breastfed as a baby	0.8	1.0	1.2	0.9	1.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	2.6	1.6	0.4
Number of full brothers	0.8	1.0	1.8	-1.3	-0.4
Migraine (self-reported)	0.8	1.0	1.2	1.1	0.9
Overall health rating	0.8	1.8	2.1	-1.5	-1.2
Major Depression (MDD)	0.7	0.9	1.1	1.1	0.8
Lung FEV1/FVC ratio	0.7	3.5	5.9	-2.4	-1.1
Diabetes (father)	0.7	0.8	1.6	-0.2	-1.3
Pack years adult smoking proportion	0.7	1.0	2.0	-1.4	0.2
Average weekly fortified wine intake	0.7	0.8	1.1	0.7	1.1
Hearing difficulty/problems with background noise	0.7	1.1	1.8	0.6	1.3
Impedance of arm (right)	0.7	3.4	6.8	2.6	0.2
Happiness	0.7	0.9	1.3	-1.1	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.0	-1.0	-0.8
Mean time to correctly identify matches	0.7	1.4	2.8	1.7	0.2
Illnesses of siblings: Diabetes	0.7	0.8	1.6	0.2	1.3
Commuting to job workplace: Walk	0.7	0.8	1.5	-0.3	-1.2
Financial situation satisfaction	0.7	0.9	1.7	1.3	0.2
Ever smoked	0.7	1.2	2.3	-0.3	-1.5
Diastolic blood pressure, automated reading	0.7	2.0	4.0	-0.1	2.0
Pain experienced in last month	0.7	1.2	2.3	-0.3	-1.5
Neuroticism (Nagel 2018)	0.6	1.4	2.7	0.4	1.6
Vitamin and mineral supplements	0.6	0.8	1.6	-0.2	-1.3
Past tobacco smoking	0.6	1.2	1.5	-0.9	1.2
Mouth/teeth dental problems	0.6	1.0	1.9	-1.4	0.1
Pain all over the body in last month	0.6	0.6	1.3	0.1	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	1.2	1.1	0.8
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.4	-1.2	-0.2
Medication: Omeprazole	0.6	0.8	0.8	-0.8	-0.9
Had major operations	0.6	0.7	1.1	-1.0	-0.5
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.1	0.4	1.1
Alzheimer’s Disease (in father)	0.5	0.6	0.6	-0.8	-0.8
Type 2 Diabetes (T2D) (2012)	0.5	0.5	1.1	0.1	1.0
Average weekly spirits intake	0.5	0.6	0.7	0.7	0.8
Medication: Metformin	0.5	0.7	0.8	0.8	0.9
Diabetes (mother)	0.5	0.6	0.7	-0.8	-0.7
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.2	0.2	-1.1
Alcohol usually taken with meals	0.5	0.8	1.6	1.2	0.2
Number of live births	0.5	0.7	1.0	0.6	1.0
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	2.8	-0.7	-1.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.8	2.9	-0.8	-1.7
Tense / ‘highly strung’	0.5	0.9	1.1	0.8	1.1
Forced vital capacity (FVC), Best measure	0.5	1.8	2.7	-1.0	-1.6
Worry too long after embarrassment	0.5	0.9	1.4	0.6	1.2
Emphysema/chronic bronchitis	0.5	0.6	0.8	0.6	0.9
Angina (self-reported)	0.5	0.6	1.1	-0.3	1.1
Loneliness, isolation	0.5	0.7	0.8	0.9	0.8
Qualifications: nursing, teaching	0.5	0.7	0.9	-0.7	-0.9
Number of self-reported non-cancer illnesses	0.5	0.9	1.6	-1.3	-0.4
Average weekly champagne plus white wine intake	0.5	0.6	1.1	1.1	0.3
Ever taken oral contraceptive pill	0.5	0.6	1.0	-1.0	-0.5
Hearing aid user	0.5	0.5	0.7	-0.8	-0.6
Medication: Bendroflumethiazide	0.5	0.7	1.5	-1.2	0.1
Age started oral contraceptive pill	0.5	0.6	1.2	1.1	0.0
Myopia	0.5	0.7	1.0	1.0	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	0.9	-1.0	-0.6
Supplements: Calcium	0.5	0.6	0.7	0.7	0.8
Heart disease (siblings)	0.5	0.7	1.3	-0.3	-1.1
Bipolar Disorder (2018)	0.4	0.7	1.2	-1.1	0.4
Alzheimer’s Disease (including proxy)	0.4	0.6	0.7	-0.8	-0.8
Prostate Cancer	0.4	0.6	0.8	-0.9	-0.7
Coronary Artery Disease (CAD)	0.4	0.5	0.8	0.3	0.9
Rheumatoid Arthritis	0.4	0.5	0.8	-0.5	-0.9
Smoking Status	0.4	0.9	1.3	0.7	-1.1
Hypothyroidism (self reported)	0.4	0.8	1.0	0.8	1.0
Number of treatments/medications taken	0.4	0.7	1.3	-1.1	0.3
Relative age of first facial hair	0.4	0.9	1.1	-0.8	1.1
Supplements: Zinc	0.4	0.4	0.7	-0.8	-0.3
Medication: Levothyroxine sodium	0.4	0.7	0.9	0.7	0.9
Forced vital capacity (FVC)	0.4	1.4	1.9	-0.9	-1.4
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.9	0.3	0.9
Depression (self-reported)	0.4	0.5	0.6	-0.8	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.0	1.0	-0.2
Age at first live birth	0.4	0.8	1.0	0.8	1.0
Medication: Seretide 50 evohaler	0.4	0.5	1.0	0.0	1.0
Chest pain or discomfort	0.4	0.6	1.2	0.1	1.1
Ever had bowel cancer screening	0.4	0.5	0.7	-0.6	-0.8
Ever had prostate specific antigen (PSA) test	0.4	0.5	0.8	-0.9	-0.4
Vascular/heart problems diagnosed by doctor	0.4	1.0	1.7	1.3	-0.6
Pack years of smoking	0.4	0.5	1.1	-1.0	0.0
Impedance of whole body	0.4	2.3	4.5	2.1	0.2
Depressed Affect (Nagel 2018)	0.3	0.6	1.1	0.2	1.1
Intelligence (Savage-Jansen 2018)	0.3	1.0	1.6	1.2	0.7
HDL Cholesterol	0.3	0.5	0.7	0.8	0.5
Height	0.3	5.7	8.2	2.9	1.8
Chronotype (morning person)	0.3	0.7	1.4	-0.1	1.2
Sensitivity / hurt feelings	0.3	0.6	1.1	0.1	1.1
Angina	0.3	0.4	0.8	-0.3	0.9
Trunk fat percentage	0.3	1.3	2.4	1.6	-0.5
High blood pressure	0.3	1.0	1.2	-1.1	0.8
Medication: Atenolol	0.3	0.4	0.7	-0.4	0.8
Heart attack	0.3	0.4	0.5	0.7	0.6
Illnesses of siblings	0.3	0.4	0.6	0.4	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.1	-1.0	0.0
Exposure to tobacco smoke at home	0.3	0.4	0.5	-0.5	-0.7
Peak expiratory flow (PEF)	0.3	0.6	1.2	-0.2	-1.1
Wheeze or whistling in the chest in last year	0.3	0.5	1.0	0.3	1.0
Number of children fathered	0.3	0.4	0.7	0.8	0.1
Pulse wave peak to peak time	0.3	0.3	0.4	0.4	0.6
Age at last live birth	0.3	0.4	0.8	-0.1	0.9
Hypertension (Self-reported)	0.3	0.8	1.0	-1.0	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.5	-0.3	-0.7
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.6	-0.3	0.8
Diabetes diagnosed by doctor	0.3	0.4	0.7	0.8	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.6	-0.3	-0.8
Asthma (self-reported)	0.3	0.6	1.1	0.4	1.0
Alcohol drinker status: Never	0.3	0.4	0.5	0.5	-0.7
Commuting to job workplace: Cycle	0.3	0.4	0.6	0.4	0.8
Cholesterol lowering medication	0.3	0.5	0.8	-0.5	-0.9
Reaction Time	0.2	0.4	0.8	0.9	-0.1
Fasting Glucose	0.2	0.3	0.5	-0.7	0.2
Ulcerative Colitis	0.2	0.3	0.5	-0.7	0.3
Type 2 Diabetes (T2D) (2018)	0.2	0.4	0.7	-0.2	-0.9
Medication: Co-codamol	0.2	0.3	0.5	-0.3	-0.7
Townsend deprivation index at recruitment	0.2	0.3	0.6	0.1	0.8
Fed-up feelings	0.2	0.3	0.6	0.1	0.8
Relative age voice broke	0.2	0.4	0.7	-0.8	0.0
Hayfever, allergic rhinitis or eczema	0.2	0.5	0.9	-0.3	-1.0
Trunk fat mass	0.2	0.8	1.3	1.1	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.6	-0.8	0.5
Arm fat percentage (right)	0.2	0.7	0.9	0.7	-0.9
Alcohol intake versus 10 years previously	0.2	0.3	0.6	-0.0	0.8
Asthma	0.2	0.4	0.7	0.3	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.3	-0.4	0.5
Pulse wave Arterial Stiffness index	0.2	0.2	0.3	-0.4	-0.6
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.3	0.4	0.6
Headache pain in last month	0.2	0.4	0.7	-0.3	0.8
Medication: Amlodipine	0.2	0.3	0.5	-0.7	-0.3
High blood pressure (siblings)	0.2	0.3	0.5	0.3	-0.7
Body fat percentage	0.2	0.9	1.5	1.2	-0.6
Arm fat-free mass (right)	0.2	1.2	2.2	-1.5	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.3	-0.4	-0.6
Arm predicted mass (right)	0.2	1.1	2.1	-1.5	-0.3
Alcohol intake frequency.	0.2	0.4	0.8	-0.9	0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.3	-0.6	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.7	-0.8	-0.2
Arm fat percentage (left)	0.2	0.9	1.3	0.6	-1.2
Osteoporosis (self-reported)	0.2	0.2	0.5	0.0	-0.7
Miserableness	0.2	0.3	0.6	-0.1	0.7
Arm fat-free mass (left)	0.2	1.0	1.8	-1.4	-0.4
Number of operations (self-reported)	0.2	0.4	0.5	-0.7	-0.5
Average weekly beer plus cider intake	0.2	0.2	0.3	-0.3	-0.6
Irritability	0.2	0.3	0.5	0.3	0.7
Risk taking	0.2	0.2	0.3	0.5	-0.5
Fractured/broken bones in last 5 years	0.2	0.2	0.3	-0.6	-0.4
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.3	0.6	0.5
Arm predicted mass (left)	0.2	1.2	2.2	-1.5	-0.5
Schizophrenia vs Biploar Disorder	0.1	0.1	0.1	-0.4	0.2
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	-0.5	0.2
Ulcerative Colitis (UC)	0.1	0.1	0.2	-0.2	0.5
Breast Cancer	0.1	0.2	0.2	0.4	-0.4
Body Mass Index (BMI) (2010)	0.1	0.1	0.2	-0.5	0.2
Mean Putamen Volume	0.1	0.2	0.2	-0.5	0.3
LDL Cholesterol	0.1	0.1	0.2	0.1	0.4
Blood Eosinophil Count	0.1	0.6	0.9	0.9	-0.5
Blood Red Count	0.1	1.4	1.5	-1.2	-1.1
Blood White Count	0.1	0.5	0.5	0.7	-0.7
BMI	0.1	0.5	0.8	0.4	-0.9
Waist Hip Ratio (WHR)	0.1	0.3	0.5	0.7	0.0
Allergy or Eczema	0.1	0.3	0.5	0.2	-0.7
Hand grip strength (left)	0.1	0.2	0.4	-0.1	0.7
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.1	-0.3	0.3
Ever had hysterectomy (womb removed)	0.1	0.1	0.1	-0.2	0.3
Impedance of leg (right)	0.1	0.4	0.8	0.9	-0.0
Leg fat-free mass (left)	0.1	0.4	0.6	-0.8	-0.5
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.2	-0.4	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.1	0.2	-0.3	0.4
Body mass index (BMI)	0.1	0.3	0.5	-0.2	-0.7
Impedance of leg (left)	0.1	0.6	1.2	1.1	0.3
Leg predicted mass (left)	0.1	0.4	0.6	-0.8	-0.4
Waist circumference	0.1	0.3	0.5	0.7	-0.3
Nervous feelings	0.1	0.3	0.3	0.4	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.2	-0.2	-0.4
Had menopause	0.1	0.1	0.1	0.4	0.1
Qualifications: None of the above	0.1	0.2	0.4	0.4	0.6
Financial difficulties in last 2 years	0.1	0.1	0.2	0.4	-0.1
Allergy	0.1	0.2	0.3	-0.6	0.1
Diabetes (self-reported)	0.1	0.2	0.4	0.6	0.2
Fluid intelligence score	0.1	0.1	0.2	0.5	0.0
Trunk fat-free mass	0.1	0.7	1.4	-1.2	0.1
Hair/balding pattern: Pattern 3	0.1	0.1	0.2	0.5	0.2
Noisy workplace	0.1	0.1	0.2	0.4	-0.2
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.5	0.3	0.7
Lung cancer (father)	0.1	0.1	0.1	0.2	0.3
Arm fat mass (right)	0.1	0.5	0.9	0.2	-1.0
Trunk predicted mass	0.1	0.7	1.4	-1.2	0.0
Hair/balding pattern: Pattern 4	0.1	0.3	0.6	-0.1	0.8
Leg fat percentage (right)	0.1	0.4	0.5	0.5	-0.7
Qualifications: College or University degree	0.1	0.2	0.3	0.2	-0.6
Medication: Ibuprofen	0.1	0.1	0.2	-0.4	0.3
Whole body fat mass	0.1	0.5	0.5	0.7	-0.6
Leg fat mass (right)	0.1	0.3	0.5	0.3	-0.7
Family relationship satisfaction	0.1	0.1	0.2	0.4	-0.1
Leg pain on walking	0.1	0.2	0.2	-0.4	0.4
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.1	0.1	-0.4
Whole body fat-free mass	0.1	0.7	1.4	-1.2	-0.1
Leg fat-free mass (right)	0.1	0.3	0.6	-0.8	-0.2
Long-standing illness, disability or infirmity	0.1	0.1	0.2	-0.2	0.4
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.3	0.2	-0.5
Whole body water mass	0.1	0.7	1.3	-1.2	-0.2
Leg predicted mass (right)	0.1	0.3	0.6	-0.8	-0.2
Arm fat mass (left)	0.1	0.5	1.0	0.1	-1.0
Guilty feelings	0.1	0.2	0.2	-0.4	0.4
Wears glasses or contact lenses	0.1	0.1	0.1	-0.3	0.3
Basal metabolic rate	0.1	0.6	1.1	-1.0	-0.4
Leg fat percentage (left)	0.1	0.3	0.4	0.7	-0.5
Unable to work because of sickness or disability	0.1	0.1	0.3	0.1	0.5
Leg fat mass (left)	0.1	0.3	0.3	0.4	-0.6
Respiratory disease	0.0	0.0	0.0	-0.0	0.1
Hair Pigment	0.0	0.2	0.4	-0.2	-0.6
Tanning	0.0	0.2	0.4	-0.2	0.6
Hand grip strength (right)	0.0	0.0	0.0	-0.0	0.2
Age when periods started (menarche)	0.0	0.1	0.2	0.4	0.1
Tinnitus: Yes, but not now, but have in the past	0.0	0.0	0.0	0.0	0.1
Sitting height	0.0	0.1	0.1	0.3	0.3
Medication: Simvastatin	0.0	0.0	0.0	0.0	-0.2
Weight	0.0	0.1	0.2	0.3	-0.4
Hip circumference	0.0	0.1	0.2	0.4	-0.3
Medication: Cholesterol lowering	0.0	0.1	0.1	-0.2	-0.3
Standing height	0.0	0.5	0.8	0.9	0.4
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.0	-0.1	0.1
Birth weight	0.0	0.1	0.1	0.4	0.2
Comparative body size at age 10	0.0	0.1	0.2	-0.3	0.4
Comparative height size at age 10	0.0	0.0	0.0	0.1	0.1
Medication: Atorvastatin	0.0	0.1	0.1	-0.3	-0.1
Basal cell carcinoma (self-reported)	0.0	0.0	0.1	0.3	-0.0

Hub : Genes

LMOD2

Models

Trait associations