Hub : Genes

POT1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1140 0.0310 4.6e-15 0.161 0.134 0.172 0.147 0.170 3.9e-19 5.8e-16 1.8e-20 1.5e-17 3.1e-20
2 GTEx Artery Coronary 0.2040 0.0820 4.9e-04 0.086 NA 0.075 NA 0.068 7.6e-04 NA 1.6e-03 NA 2.6e-03
3 GTEx Spleen 0.2540 0.0940 3.1e-04 0.157 NA 0.004 NA 0.101 7.9e-05 NA 2.5e-01 NA 1.5e-03
4 TCGA Bladder Urothelial Carcinoma 0.0320 0.0230 2.1e-03 0.032 0.020 0.000 NA 0.014 9.6e-04 7.3e-03 2.9e-01 NA 2.2e-02
5 TCGA Breast Invasive Carcinoma 0.0126 0.0102 6.4e-03 0.004 0.010 0.006 NA 0.005 3.8e-02 3.2e-03 2.1e-02 NA 2.3e-02
6 TCGA Kidney Renal Clear Cell Carcinoma 0.0551 0.0477 2.9e-04 0.042 0.036 0.034 NA 0.039 1.4e-05 5.8e-05 8.7e-05 NA 3.1e-05
7 TCGA Brain Lower Grade Glioma 0.0660 0.0399 1.2e-05 0.042 0.044 0.052 NA 0.037 1.5e-05 8.9e-06 1.3e-06 NA 4.1e-05
8 TCGA Thyroid Carcinoma 0.0740 0.0330 2.1e-07 0.090 0.078 0.088 NA 0.089 4.5e-09 4.9e-08 6.7e-09 NA 5.4e-09

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.9 3.1 4.7 0.9 -2.0 2.0 2.2 2.0 1.9 1.3 1.4
Bipolar Disorder or Schizophrenia 0.3 0.7 2.0 0.3 -0.0 1.1 1.4 1.2 0.7 0.5 0.6
Depressed Affect (Nagel 2018) 1.8 3.8 5.6 2.2 -1.7 2.3 2.4 2.2 1.8 1.4 1.3
Depression (Nagel 2018) 0.3 0.5 1.1 0.8 0.1 0.5 0.4 0.8 0.4 1.0 0.7
Intelligence (Savage-Jansen 2018) 2.0 6.2 7.9 2.5 -1.8 2.1 2.5 2.8 2.7 2.6 2.7
Neuroticism (Nagel 2018) 2.9 6.9 13.8 2.5 -2.5 3.7 3.3 2.8 2.3 1.7 1.4
Schizophrenia (2018) 0.2 0.4 2.5 -0.3 1.6 -0.2 0.1 -0.1 -0.6 -0.4 -0.4
Schizophrenia vs Biploar Disorder 0.7 0.9 2.7 -0.3 1.6 -0.6 -1.1 -0.9 -1.3 -0.6 -0.6
Worry (Nagel 2018) 0.7 1.4 4.6 0.5 -1.7 2.1 1.7 0.9 0.4 0.1 -0.5
Alzheimer’s Disease (in mother) 0.5 0.6 1.6 -0.8 -0.6 -0.2 -0.2 -0.5 -1.3 -0.6 -1.2
Alzheimer’s Disease (in father) 1.2 1.3 2.6 -1.4 1.6 -0.7 -0.7 -1.0 -1.1 -1.3 -1.1
Alzheimer’s Disease (including proxy) 1.7 2.5 5.2 -2.3 0.3 -0.8 -1.0 -1.5 -2.0 -1.6 -1.9
Crohns Disease (2017) 0.2 0.4 1.5 -0.6 0.6 -0.8 -1.2 -0.5 -0.0 -0.2 0.5
Irritable Bowel Disease (IBD) 0.4 0.9 1.7 -0.7 1.3 -0.7 -1.2 -1.1 -0.5 -1.0 -0.5
Ulcerative Colitis (UC) 0.6 1.1 1.8 -0.6 1.4 -0.4 -0.8 -1.2 -0.8 -1.3 -1.3
Major Depression (MDD) 0.9 1.0 2.1 1.5 -0.5 0.6 1.0 1.2 1.1 0.9 1.1
Reaction Time 0.2 0.4 1.3 0.1 1.0 -1.1 -0.7 -0.1 -0.7 0.2 0.4
Verbal and Numeric Reasoning (VNR) 1.8 4.4 7.7 2.7 0.4 0.7 1.5 2.3 2.5 2.4 2.8
Breast Cancer 1.0 2.5 3.8 -1.9 -0.0 -0.8 -1.6 -1.7 -1.9 -1.9 -1.8
Ovarian Cancer 0.6 0.8 2.2 0.8 -1.5 1.1 1.1 0.5 0.5 0.8 -0.1
Prostate Cancer 0.6 0.8 2.7 1.2 0.0 1.7 1.2 0.6 0.8 0.3 -0.0
Age at First Birth 0.2 0.3 0.5 0.4 0.3 0.6 0.5 0.6 0.5 0.6 0.7
Bipolar Disorder (2011) 3.0 2.9 5.8 1.1 -2.2 2.4 2.4 1.7 1.2 0.8 0.7
Body Mass Index (BMI) (2010) 0.9 1.2 2.7 -1.0 0.1 -1.6 -1.5 -1.1 -1.1 -0.7 -0.7
Coronary Artery Disease (CAD) 1.4 1.7 3.4 -1.9 0.8 -1.5 -1.6 -1.5 -0.9 -1.2 -0.8
Crohns Disease (2012) 0.2 0.3 0.8 -0.2 0.9 -0.2 -0.3 0.2 0.3 0.6 0.8
Mean Putamen Volume 0.8 0.9 2.3 0.6 0.9 0.0 0.4 1.0 0.9 1.3 1.5
Fasting Glucose 0.7 0.8 2.5 -0.7 1.6 -1.0 -1.0 -0.9 -0.7 -0.3 -0.5
HbA1C 0.3 0.3 0.8 0.4 0.8 -0.1 0.1 0.6 0.5 0.8 0.9
HDL Cholesterol 0.4 0.6 1.7 -0.4 -0.9 1.3 1.3 0.8 0.5 0.1 -0.0
LDL Cholesterol 0.0 0.1 0.1 -0.2 0.1 0.3 0.3 -0.0 -0.1 -0.3 -0.3
Lupus 1.8 2.7 6.7 1.6 -2.0 2.6 2.0 1.3 1.3 0.6 0.4
Neuroticism (2016) 2.1 3.1 5.7 1.3 -2.4 2.3 2.3 1.8 1.6 0.6 0.7
Primary Biliary Cirrhosis 0.5 0.7 1.8 -0.5 -0.2 -0.2 -0.6 -1.0 -0.8 -1.2 -1.4
Rheumatoid Arthritis 0.1 0.1 0.3 -0.3 -0.1 -0.2 -0.1 -0.1 -0.5 -0.4 -0.3
Schizophrenia (2014) 0.4 0.9 1.6 1.1 1.3 1.0 1.1 1.1 0.6 0.6 0.7
Triglycerides 0.3 0.6 1.8 -0.4 -1.3 0.6 0.5 0.1 -0.7 -0.5 -1.1
Type 2 Diabetes (T2D) (2012) 0.5 0.5 1.6 0.0 0.1 -0.0 0.2 0.6 1.0 1.1 1.3
Ulcerative Colitis 0.1 0.2 0.4 0.0 0.6 -0.0 -0.3 -0.5 -0.1 -0.5 -0.6
Blood Eosinophil Count 0.5 4.2 11.4 -0.1 3.2 -3.4 -2.5 -0.5 0.3 0.9 2.1
Blood Platelet Count 1.7 19.1 29.5 4.1 -4.1 5.4 5.4 4.7 4.5 3.3 3.0
Blood Red Count 0.5 4.9 17.0 1.7 -2.0 4.1 3.1 1.7 1.1 1.2 -0.4
Blood White Count 0.0 0.2 0.6 -0.1 0.1 0.3 -0.1 0.2 0.7 0.8 0.4
Heel T-Score 0.0 0.1 0.3 -0.6 0.3 -0.2 -0.1 0.1 0.1 -0.2 -0.0
BMI 0.3 1.9 4.3 0.7 -1.6 0.9 0.7 1.5 1.2 2.1 1.7
Height 0.1 2.2 5.2 -2.2 1.2 -2.3 -1.6 -1.3 -0.6 -1.3 0.1
Waist Hip Ratio (WHR) 0.1 0.6 1.7 0.7 -1.3 1.1 0.8 0.6 0.3 0.3 -0.0
Systolic Blood Pressure 0.4 1.8 5.2 0.6 -2.2 2.3 1.4 0.5 -0.5 0.1 -1.2
Smoking Status 2.1 4.9 8.9 1.6 -3.0 2.2 2.1 2.3 2.4 2.0 1.9
Allergy or Eczema 1.1 3.0 4.1 1.9 -0.8 1.7 2.0 2.0 1.7 1.9 1.4
Cardiovascular Disease 0.5 1.6 8.2 -0.1 -2.9 1.6 0.9 0.2 -0.2 -0.7 -0.9
Hypothyroidism (self reported) 0.4 1.0 3.3 1.1 0.1 -0.6 0.0 0.8 1.4 0.7 1.8
Respiratory disease 0.2 0.5 1.9 -1.4 -0.4 -0.6 -0.5 -0.7 -0.3 -0.6 -0.7
Type 2 Diabetes (T2D) (2018) 0.2 0.3 0.7 0.7 -0.5 -0.6 -0.8 -0.2 0.3 0.5 0.5
Lung FEV1/FVC ratio 1.2 6.1 9.0 2.4 -2.0 2.5 3.0 3.0 2.1 2.5 2.2
Lung FVC 0.2 0.8 2.4 -0.8 0.1 0.4 -0.1 -0.9 -0.8 -1.3 -1.6
Neuroticism 2.1 5.2 12.6 1.5 -3.2 3.5 3.1 2.0 1.3 0.8 -0.1
Chronotype (morning person) 0.9 2.0 4.5 -1.4 -1.3 -0.3 -0.5 -1.5 -1.6 -1.6 -2.1
Hair Pigment 0.0 0.8 4.2 0.4 -2.0 0.8 0.7 0.5 0.2 0.5 0.2
Tanning 0.1 0.9 1.8 -1.3 -1.1 0.2 -0.1 -0.9 -0.9 -1.0 -1.3
Hand grip strength (left) 2.4 6.4 8.3 -2.6 2.2 -2.4 -2.6 -2.9 -2.8 -2.2 -2.4
Number of treatments/medications taken 0.5 0.9 2.0 0.6 -1.4 1.0 0.7 1.1 0.8 0.6 0.9
Average weekly spirits intake 0.5 0.6 1.5 1.0 -0.4 1.2 0.8 0.6 0.6 0.6 0.3
Sensitivity / hurt feelings 0.7 1.2 5.5 -0.3 -2.4 1.2 0.7 -0.0 -0.3 -0.6 -1.0
Frequency of depressed mood in last 2 weeks 0.0 0.1 0.2 -0.0 -0.5 0.2 0.2 0.3 0.1 0.3 -0.0
Hearing difficulty/problems: Yes 0.9 1.4 4.1 0.6 -1.5 2.0 1.6 1.2 0.6 0.4 0.2
Relative age of first facial hair 0.3 0.6 1.9 0.3 1.4 -1.0 -0.6 -0.1 -0.0 0.9 0.6
Other serious medical condition/disability diagnosed by doctor 1.8 2.3 3.7 1.0 -1.6 1.9 1.7 1.7 1.7 1.0 1.2
Ever used hormone-replacement therapy (HRT) 1.8 2.3 3.4 1.2 -1.1 1.6 1.9 1.8 1.8 0.5 1.7
Ever had hysterectomy (womb removed) 3.6 4.1 10.2 1.0 -3.2 2.4 2.5 2.1 1.5 1.4 1.0
Systolic blood pressure, automated reading 0.4 1.3 4.2 0.3 -1.8 2.1 1.3 0.8 0.5 0.5 -0.3
Eye problems/disorders: Diabetes related eye disease 1.7 1.9 3.5 -1.0 0.3 -1.2 -1.6 -1.7 -1.2 -1.9 -1.6
Angina 0.0 0.0 0.2 0.5 -0.2 -0.0 -0.3 0.1 -0.1 -0.2 -0.0
Medication for hormone replacement therapy 0.2 0.3 1.5 -0.1 -1.2 0.0 0.2 -0.0 -0.3 -0.6 -0.4
Vitamin and mineral supplements 3.4 4.6 6.8 2.0 -1.3 1.8 1.9 2.3 2.5 2.6 2.4
Supplements: Zinc 0.2 0.2 0.4 -0.0 -0.1 -0.4 -0.6 -0.6 -0.6 0.3 -0.4
Medication: Co-codamol 0.6 0.7 3.4 -1.2 -1.8 0.1 0.2 0.2 -0.3 -0.4 -0.4
Medication: Metformin 0.2 0.3 0.7 -0.4 -0.7 -0.7 -0.9 -0.5 -0.1 0.1 -0.2
Diabetes (father) 0.4 0.5 1.5 1.2 -0.4 0.7 0.7 0.8 0.9 0.4 0.6
Diabetes (mother) 0.9 1.1 2.9 0.7 -1.7 1.0 0.8 1.1 0.7 1.3 0.7
Severe depression (siblings) 5.5 6.1 10.6 1.9 -2.5 3.2 3.3 2.8 2.2 1.8 1.5
Pack years adult smoking proportion 0.6 1.0 3.1 0.9 -0.4 -0.4 -0.1 0.8 1.1 1.2 1.8
Impedance of leg (right) 0.3 1.3 1.6 -1.3 0.7 -1.2 -1.0 -1.3 -1.1 -1.2 -1.1
Leg fat-free mass (left) 0.1 0.7 2.0 0.6 0.3 -0.1 -0.0 0.7 1.0 1.4 1.3
Trunk fat percentage 0.4 1.7 2.9 0.9 -1.0 0.9 0.9 1.5 1.4 1.7 1.7
Hand grip strength (right) 6.2 16.9 22.6 -4.0 3.8 -3.9 -4.4 -4.8 -4.1 -3.9 -3.8
Townsend deprivation index at recruitment 3.0 4.2 6.2 1.9 -1.5 2.4 2.5 2.2 2.0 2.1 1.6
Current tobacco smoking 0.7 1.2 4.6 0.5 -2.1 0.2 0.4 0.8 1.0 1.2 1.1
Average weekly fortified wine intake 0.3 0.3 0.7 -0.7 0.8 -0.3 -0.3 -0.3 -0.6 -0.7 -0.3
Maternal smoking around birth 0.2 0.4 1.7 -1.0 -1.3 0.0 0.2 0.1 0.1 0.2 -0.1
Fed-up feelings 0.2 0.3 1.8 -0.1 -1.3 0.1 0.2 0.1 -0.4 -0.3 -0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.0 0.1 0.2 0.3 -0.1 0.3 -0.0 0.3 -0.2 0.5 0.1
Relative age voice broke 0.2 0.3 1.2 0.8 0.2 0.1 0.1 0.4 0.5 1.1 0.6
Taking other prescription medications 2.4 3.8 7.8 2.0 -0.8 1.0 1.3 2.3 2.4 2.0 2.8
Age when periods started (menarche) 0.7 1.7 2.9 -1.5 1.3 -1.6 -1.7 -1.5 -0.8 -1.1 -0.6
Bilateral oophorectomy (both ovaries removed) 2.8 3.3 5.3 1.3 -2.0 2.1 2.3 2.0 1.7 1.4 1.4
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 1.9 0.1 -0.4 1.3 1.2 1.4 1.2 1.2 1.1
Tinnitus: Yes, but not now, but have in the past 1.1 1.1 3.0 0.3 -1.7 1.6 1.1 0.9 0.7 0.8 0.5
Qualifications: CSEs or equivalent 3.8 5.0 7.3 -1.9 1.6 -2.7 -2.6 -2.6 -2.4 -1.7 -2.0
Serious illness, injury or assault to yourself 0.4 0.4 1.0 0.2 0.1 0.7 0.9 1.0 0.7 0.4 0.7
High blood pressure 0.7 1.9 10.2 0.6 -3.2 1.7 1.1 0.8 0.4 0.1 -0.0
Hayfever, allergic rhinitis or eczema 0.5 1.0 2.3 1.0 -0.3 0.5 0.9 1.2 0.9 1.5 1.1
Multivitamins +/- minerals 1.8 2.2 4.6 -1.2 0.6 -0.7 -0.8 -1.5 -2.0 -2.1 -2.1
Stomach or abdominal pain in last month 1.1 1.4 2.5 0.7 -0.3 1.1 1.3 1.6 1.5 1.3 1.2
Supplements: Glucosamine 1.4 1.8 4.2 -1.8 -0.2 -0.5 -0.6 -1.2 -1.8 -1.3 -2.1
Diverticular disease/diverticulitis (self-reported) 2.9 3.5 5.3 1.9 -1.1 2.3 2.3 2.1 1.8 1.6 1.4
Medication: Atenolol 0.4 0.5 1.2 1.1 -0.7 0.4 0.4 0.7 0.5 0.7 0.7
Medication: Levothyroxine sodium 0.1 0.2 0.7 -0.1 -0.0 -0.8 -0.4 0.1 0.3 -0.1 0.7
Sitting height 0.1 0.5 2.5 0.1 1.6 -0.7 -0.3 0.0 0.6 0.1 0.8
Chronic bronchitis/emphysema (father) 0.8 0.9 2.1 -1.0 -0.1 -0.8 -1.0 -1.1 -0.7 -1.4 -0.8
High blood pressure (mother) 0.3 0.4 0.7 -0.9 -0.8 -0.2 -0.4 -0.6 -0.2 -0.8 -0.6
Body mass index (BMI) 0.4 1.5 3.6 0.9 -1.3 0.9 0.6 1.2 1.2 1.9 1.4
Impedance of leg (left) 0.3 1.6 2.9 -1.7 0.4 -1.2 -1.0 -1.4 -1.3 -1.5 -1.3
Leg predicted mass (left) 0.1 0.7 1.9 0.5 0.3 -0.1 0.0 0.7 1.0 1.4 1.2
Trunk fat mass 0.4 1.7 3.2 0.8 -1.0 0.9 0.8 1.5 1.4 1.8 1.6
Waist circumference 0.6 2.3 3.6 1.1 -1.9 1.2 1.1 1.6 1.4 1.9 1.6
Number of incorrect matches in round 1.7 2.8 4.4 -1.8 0.1 -1.2 -1.5 -1.9 -1.9 -2.0 -2.1
Past tobacco smoking 2.4 4.3 7.7 -1.6 2.8 -2.5 -2.3 -2.0 -2.0 -1.8 -1.3
Alcohol usually taken with meals 0.4 0.6 1.8 -0.2 0.1 0.9 1.4 0.8 1.2 0.2 0.5
Nervous feelings 2.1 3.9 6.1 1.9 -1.5 2.4 2.5 2.1 2.2 1.7 1.3
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.3 0.9 0.1 0.0 0.9 0.1 -0.3 -0.4 -0.0 -0.9
Hearing difficulty/problems with background noise 1.8 2.9 4.6 1.1 -2.2 2.0 1.9 1.9 1.4 1.7 1.4
Hair/balding pattern: Pattern 2 1.2 1.6 3.1 1.3 -0.0 0.8 1.1 1.4 1.5 1.8 1.3
Had menopause 0.3 0.4 1.1 -0.8 -0.2 -0.5 -0.5 -0.5 -0.7 -1.0 -0.5
Had other major operations 1.7 2.1 3.4 0.9 -1.3 0.9 1.5 1.8 1.7 1.5 1.6
Forced vital capacity (FVC) 0.2 0.8 4.0 -0.7 2.0 -0.4 -0.5 -0.7 -0.6 -0.5 -0.8
Heel bone mineral density (BMD) T-score, automated (right) 1.2 2.8 4.5 0.9 -1.1 1.4 1.6 1.9 2.1 2.0 1.9
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 1.5 0.1 0.8 -0.9 -0.9 -0.8 -0.8 -1.2 -0.5
Qualifications: None of the above 0.6 1.3 3.1 -1.5 -0.6 0.1 -0.5 -1.2 -1.2 -1.2 -1.8
Financial difficulties in last 2 years 1.4 1.9 6.3 0.1 -2.5 1.9 1.9 1.0 0.5 0.7 -0.4
Mouth/teeth dental problems 1.2 1.8 3.0 -1.5 0.6 -1.7 -1.7 -1.4 -1.3 -1.2 -1.1
Heart attack 0.6 0.8 1.9 1.0 0.1 0.1 0.4 0.9 1.1 1.4 1.2
Allergy 0.1 0.1 0.5 -0.2 0.2 0.4 -0.0 -0.3 -0.1 -0.7 -0.4
Pain all over the body in last month 4.7 5.0 6.9 2.0 -1.8 2.3 2.4 2.4 2.2 2.6 2.0
Diabetes (self-reported) 2.3 3.5 6.1 2.0 -2.5 1.2 1.3 1.9 2.0 2.0 2.0
Hayfever/allergic rhinitis (self-reported) 3.6 4.8 8.1 1.5 -1.5 2.6 2.8 2.6 2.4 1.9 1.7
Medication: Ramipril 1.6 2.1 4.8 -1.0 0.4 -1.8 -2.2 -1.6 -1.7 -1.0 -1.0
Medication: Simvastatin 0.2 0.4 2.0 0.2 -1.4 0.5 -0.2 0.1 0.5 0.5 0.2
Fluid intelligence score 1.4 2.8 4.7 1.9 1.5 0.8 1.3 1.8 1.8 1.9 2.2
Illnesses of siblings 1.8 2.5 5.0 1.4 -0.7 1.3 1.7 1.8 2.2 1.3 1.7
Neuroticism score 1.1 2.2 6.2 0.4 -2.5 2.5 1.9 0.9 0.3 0.0 -0.7
Weight 0.1 0.7 2.1 0.4 -0.2 -0.1 -0.1 0.7 0.9 1.5 1.4
Impedance of arm (right) 0.1 0.7 1.5 -0.8 0.9 -0.7 -0.5 -0.8 -0.8 -1.2 -0.9
Arm fat percentage (right) 0.2 0.9 1.7 0.6 -1.3 0.9 0.6 1.0 0.8 1.3 0.9
Trunk fat-free mass 0.1 0.5 1.1 -0.7 0.8 -1.0 -1.0 -0.5 0.0 0.5 0.2
Hip circumference 0.2 0.7 2.0 0.1 -0.3 -0.0 -0.1 0.8 0.9 1.4 1.4
Time employed in main current job 1.1 1.3 5.5 0.1 2.4 -1.4 -1.1 -0.9 -0.5 -0.6 -0.4
Alcohol intake versus 10 years previously 0.1 0.2 0.7 0.2 0.1 -0.7 -0.1 0.3 0.3 0.3 0.8
Father’s age at death 1.2 1.6 3.5 1.1 -1.6 1.9 1.6 1.2 0.9 0.1 0.5
Worrier / anxious feelings 1.1 2.2 3.9 1.6 -0.3 2.0 1.8 1.6 1.5 1.3 1.0
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 1.1 0.9 -0.7 1.1 0.9 0.8 0.4 0.3 0.1
Falls in the last year 0.2 0.2 0.8 -0.9 0.1 0.2 -0.1 -0.4 -0.6 -0.2 -0.7
Hair/balding pattern: Pattern 3 0.3 0.4 0.9 -0.7 1.0 -0.2 -0.3 -0.6 -0.6 -0.8 -0.5
Number of live births 0.4 0.5 1.4 -0.6 0.1 -0.9 -1.2 -1.1 -0.3 -0.5 -0.5
Forced expiratory volume in 1-second (FEV1) 0.1 0.3 1.5 -0.3 1.2 0.4 0.2 -0.2 -0.2 -0.1 -0.6
Pulse rate 0.2 0.4 1.3 0.9 -1.1 0.1 0.1 0.1 0.7 0.4 0.3
Happiness 1.7 2.0 4.8 1.4 1.5 -0.8 -0.4 1.0 1.6 1.7 2.2
Noisy workplace 2.5 3.1 6.9 2.6 -0.1 1.5 1.6 1.8 1.9 1.5 2.0
Qualifications: A levels/AS levels or equivalent 2.1 4.6 7.5 1.7 -0.6 1.7 2.3 2.7 2.4 2.7 2.2
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 0.7 0.7 -0.9 0.7 0.8 0.4 -0.3 0.1 -0.4
Mouth/teeth dental problems: Dentures 2.5 4.2 5.9 2.0 -1.1 1.8 1.9 2.3 2.3 2.2 2.4
Asthma 0.5 1.1 3.1 -1.8 -0.0 -1.1 -0.9 -1.1 -0.9 -0.6 -1.0
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.1 1.8 -1.1 0.4 -1.0 -1.2 -1.2 -1.1 -1.4 -0.8
Medication: Cholesterol lowering 0.2 0.2 0.7 0.6 -0.7 0.8 0.0 0.2 0.5 0.3 -0.1
Depression (self-reported) 1.0 1.1 3.5 0.9 -1.9 0.3 0.7 1.1 0.9 0.7 1.2
Medication: Lansoprazole 1.5 1.7 3.2 1.7 0.1 0.5 0.9 1.5 1.1 1.6 1.8
Prospective memory result 1.1 1.3 2.3 1.5 -0.9 1.1 1.0 1.1 0.9 1.4 1.1
Lung cancer (father) 0.0 0.0 0.1 0.2 -0.1 0.1 0.2 0.2 0.1 0.2 0.2
Illnesses of mother 0.7 0.9 1.8 1.3 1.2 0.2 0.6 0.8 0.8 1.1 1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.2 0.5 -0.1 0.1 0.6 0.6 0.2 -0.2 0.1 -0.7
Pulse wave Arterial Stiffness index 1.8 2.1 4.4 1.5 -0.3 0.9 1.1 1.5 1.7 2.1 1.7
Impedance of arm (left) 0.0 0.1 0.5 -0.2 0.7 -0.2 0.0 -0.1 -0.1 -0.6 -0.2
Arm fat mass (right) 0.2 1.0 2.5 0.5 -1.1 0.5 0.4 1.1 0.9 1.6 1.2
Trunk predicted mass 0.1 0.4 1.1 -0.7 0.8 -1.0 -0.9 -0.5 0.0 0.5 0.2
Standing height 0.2 2.2 6.2 -1.3 2.5 -2.2 -1.5 -1.2 -0.5 -0.8 -0.1
Length of working week for main job 1.8 2.0 4.4 1.1 0.5 0.9 1.1 1.4 1.7 2.1 1.8
Exposure to tobacco smoke at home 0.2 0.2 1.0 -0.3 -1.0 -0.3 0.3 0.4 -0.2 0.1 0.3
Breastfed as a baby 0.7 0.9 1.8 -1.0 -0.9 -0.5 -0.7 -1.0 -0.9 -0.9 -1.3
Tense / ‘highly strung’ 0.5 0.8 1.6 -0.9 -1.0 0.7 0.0 -0.6 -0.9 -1.2 -1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 0.9 2.1 0.8 -1.0 1.4 1.4 1.0 0.7 0.4 0.4
Hair/balding pattern: Pattern 4 0.4 0.9 1.8 -0.8 0.7 0.0 -0.5 -0.9 -1.2 -1.4 -1.2
Birth weight of first child 0.0 0.1 0.2 0.0 0.4 0.1 0.2 0.1 0.4 -0.1 0.5
Peak expiratory flow (PEF) 0.1 0.2 0.7 -0.9 0.4 0.1 0.4 0.2 -0.1 0.5 -0.1
Pulse wave reflection index 0.6 0.8 1.2 0.4 0.8 0.8 0.8 1.0 0.8 1.1 1.1
Ever highly irritable/argumentative for 2 days 0.6 0.7 1.5 -0.4 -0.3 -0.6 -0.6 -1.0 -1.1 -0.9 -1.2
Loud music exposure frequency 0.4 0.4 0.9 -0.0 0.5 -0.7 -0.9 -0.8 -0.8 -0.6 -0.3
Qualifications: O levels/GCSEs or equivalent 0.8 1.3 2.2 1.2 -0.6 0.7 1.2 1.5 1.2 1.3 1.3
Mouth/teeth dental problems: Bleeding gums 1.4 1.8 3.3 1.2 -1.3 1.7 1.8 1.3 0.9 1.2 0.8
Blood clot in the leg (DVT) 0.9 1.1 2.3 1.5 0.7 0.7 0.6 1.0 0.7 1.4 1.4
Medication: Paracetamol 0.6 1.0 1.8 0.5 -0.9 1.3 1.2 1.3 0.8 1.1 0.6
Headache pain in last month 0.9 1.5 3.2 1.1 -0.5 1.3 1.4 1.4 1.1 1.8 0.9
Medication for cholesterol, blood pressure or diabetes 0.4 0.6 2.8 -0.1 1.7 -1.1 -0.3 0.1 0.2 0.5 0.7
Glaucoma (self-reported) 1.1 1.3 3.1 -0.8 0.5 -0.8 -1.1 -1.3 -1.7 -1.2 -1.3
Gout (self-reported) 0.4 0.6 3.6 1.9 -0.5 -0.1 -0.2 0.4 0.3 -0.2 0.7
Hypothyroidism/myxoedema (self-reported) 0.3 0.7 2.6 0.9 0.1 -0.8 -0.3 0.5 0.9 0.4 1.6
Medication: Amlodipine 0.9 1.2 7.0 0.2 -2.6 0.9 1.1 0.8 0.2 0.2 0.1
Medication: Ventolin 100micrograms inhaler 1.4 1.9 4.5 -2.1 1.3 -2.0 -1.8 -1.1 -0.7 0.1 0.0
Birth weight 0.8 1.7 4.7 -0.9 2.2 -1.3 -1.4 -1.2 -1.2 -0.9 -0.6
Chronic bronchitis/emphysema (mother) 1.0 1.1 1.5 1.2 -1.0 1.0 1.2 1.2 1.0 1.0 0.7
High blood pressure (siblings) 2.1 3.0 4.7 -1.4 0.7 -1.1 -1.7 -2.2 -2.0 -1.9 -2.1
Forced vital capacity (FVC), Best measure 0.0 0.2 1.0 -0.2 1.0 0.0 0.2 -0.0 -0.2 -0.1 -0.5
Body fat percentage 0.4 1.4 2.7 0.8 -1.2 0.8 0.7 1.3 1.2 1.6 1.5
Leg fat percentage (right) 0.3 1.0 2.4 0.6 -1.2 0.7 0.5 1.0 0.9 1.6 1.2
Arm fat-free mass (right) 0.1 0.5 1.7 0.1 0.3 -0.4 -0.3 0.4 0.8 1.3 1.1
Exposure to tobacco smoke outside home 3.0 4.1 5.7 2.0 -0.9 1.9 2.0 2.4 2.0 2.2 2.3
Comparative body size at age 10 2.2 6.1 8.0 -2.7 1.6 -2.6 -2.8 -2.6 -2.6 -2.4 -2.1
Number of full brothers 0.8 1.0 3.3 -0.3 -1.8 1.5 1.2 0.4 -0.3 -0.1 -0.8
Worry too long after embarrassment 3.1 5.3 12.5 1.8 -1.8 3.5 3.0 2.3 2.3 1.6 1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 1.5 0.3 -1.2 0.9 0.9 0.7 0.2 0.2 0.0
Wheeze or whistling in the chest in last year 0.4 0.7 1.7 -0.9 0.7 -1.3 -1.1 -0.9 -0.6 -0.4 -0.3
Number of children fathered 2.4 2.7 4.2 1.3 -0.5 1.1 1.7 2.1 1.9 1.9 2.0
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 2.3 0.6 -0.2 1.5 1.5 1.0 0.8 0.3 0.5
Age at first live birth 0.5 0.9 2.8 -1.3 1.7 -0.6 -0.8 -0.6 -0.5 -0.9 -0.5
Pulse wave peak to peak time 2.6 3.1 5.9 -1.8 0.5 -1.3 -1.4 -1.8 -2.0 -2.4 -2.0
Health satisfaction 1.5 2.0 4.6 1.4 0.7 0.4 0.4 1.4 1.6 1.9 2.1
Shortness of breath walking on level ground 0.0 0.0 0.1 -0.3 0.2 0.4 -0.0 -0.0 0.2 -0.0 -0.1
Qualifications: College or University degree 1.0 3.3 5.3 1.3 0.1 1.6 2.2 2.3 1.9 2.2 1.9
Eye problems/disorders: None of the above 0.9 1.0 1.4 -0.5 1.2 -0.9 -1.2 -1.2 -1.0 -1.1 -0.9
Mouth/teeth dental problems: Loose teeth 0.2 0.3 0.8 0.5 -0.9 0.3 0.2 0.5 0.6 0.2 0.6
Emphysema/chronic bronchitis 0.2 0.2 0.6 0.1 0.2 -0.8 -0.7 -0.1 0.3 -0.4 0.6
Medication for pain relief, constipation, heartburn 0.2 0.3 0.7 0.8 0.8 0.1 0.3 0.3 0.5 0.1 0.6
Neck or shoulder pain in last month 1.1 1.6 3.4 -1.8 -0.8 -1.5 -1.2 -1.3 -1.4 -0.9 -1.1
Medication: Blood pressure 0.4 0.6 3.7 0.2 -1.9 0.9 0.1 -0.0 -0.4 -0.4 -0.5
Angina (self-reported) 0.0 0.1 0.2 0.5 -0.2 -0.1 -0.4 -0.0 -0.1 -0.3 -0.1
Migraine (self-reported) 1.4 1.7 3.4 1.4 0.5 1.3 1.8 1.5 1.1 1.5 0.7
Medication: Ibuprofen 0.4 0.5 1.0 -0.6 -0.2 -0.5 -0.8 -0.8 -0.7 -1.0 -0.5
Medication: Allopurinol 0.2 0.3 1.2 1.1 -0.9 -0.3 -0.4 -0.1 -0.1 -0.4 -0.1
Medication: Omeprazole 0.7 0.8 2.0 1.1 0.0 0.1 0.2 0.7 1.4 1.0 1.3
Medication: Seretide 50 evohaler 0.6 0.6 1.7 -0.5 1.1 -1.3 -1.1 -0.7 0.0 0.2 0.4
Mean time to correctly identify matches 0.1 0.2 0.8 0.3 0.7 -0.9 -0.4 0.2 -0.2 -0.0 0.4
Heart disease (mother) 0.9 1.1 3.4 0.7 -1.8 1.2 0.9 0.9 0.5 0.9 0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 0.9 -0.6 0.6 -0.4 -0.6 -0.8 -0.9 -0.7 -0.7
Whole body fat mass 0.3 1.4 3.2 0.7 -1.1 0.7 0.6 1.3 1.3 1.8 1.6
Leg fat mass (right) 0.5 1.8 4.3 1.0 -1.1 0.8 0.7 1.4 1.4 2.1 1.7
Arm predicted mass (right) 0.1 0.4 1.2 -0.3 0.4 -0.7 -0.5 0.1 0.5 1.1 0.9
Pulse rate, automated reading 0.4 1.4 4.2 0.8 -2.1 1.6 1.1 0.9 1.4 0.4 0.6
Alcohol intake frequency. 1.2 2.7 4.9 2.0 -0.3 0.5 1.3 1.9 1.6 2.1 2.2
Comparative height size at age 10 0.3 1.4 3.8 -0.5 1.9 -1.9 -1.4 -1.0 -0.6 -0.7 -0.2
Number of full sisters 0.1 0.1 0.4 0.1 0.0 -0.5 -0.6 -0.5 0.0 -0.1 -0.2
Suffer from ‘nerves’ 0.4 0.6 2.2 0.4 -1.5 1.0 0.7 0.5 0.5 0.4 0.0
Overall health rating 0.6 1.2 2.4 1.5 -1.1 1.2 1.0 1.2 0.9 1.0 0.9
Chest pain or discomfort 1.3 1.9 2.8 1.6 -0.4 1.1 1.3 1.6 1.5 1.7 1.4
Had major operations 1.2 1.4 3.0 -1.0 1.4 -1.7 -1.6 -1.1 -0.8 -0.7 -0.5
Age at last live birth 0.1 0.2 0.4 -0.6 0.6 0.3 0.2 0.2 0.3 0.5 0.1
Family relationship satisfaction 0.3 0.3 0.9 0.7 0.9 -0.9 -0.4 -0.1 0.0 0.5 0.3
Leg pain on walking 0.3 0.4 1.1 0.6 0.5 0.0 0.1 0.7 0.8 0.7 1.0
Qualifications: NVQ or HND or HNC or equivalent 1.0 1.2 2.4 -0.2 0.5 -0.7 -1.0 -1.3 -1.1 -1.6 -1.5
Commuting to job workplace: Car/motor vehicle 0.4 0.4 1.4 -0.1 0.2 -1.1 -1.2 -0.6 -0.3 -0.5 0.2
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 1.6 0.3 1.2 -1.3 -1.1 -0.4 0.4 -0.0 0.7
Medication: Aspirin 0.6 0.8 4.5 0.3 -2.1 1.1 0.8 0.5 0.1 0.2 -0.3
Supplements: Vitamin C 2.1 2.5 5.0 -2.2 0.3 -1.3 -1.3 -1.6 -2.0 -1.4 -1.7
Knee pain experienced in last month 0.4 0.7 2.7 -0.3 0.9 -1.6 -1.1 -0.4 -0.4 0.2 0.3
Hypertension (Self-reported) 0.9 2.4 12.4 0.6 -3.5 1.9 1.4 0.9 0.3 -0.1 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.4 1.7 4.5 1.7 0.5 -0.3 0.4 1.2 1.6 1.3 2.1
Illnesses of father: Heart disease 0.5 0.7 1.8 1.1 1.3 -1.1 -0.5 0.2 0.4 0.7 0.9
Illnesses of siblings: Diabetes 0.7 0.8 1.7 -1.0 -1.3 -0.6 -0.8 -0.8 -1.2 -0.4 -0.9
Smoking status: Previous 2.1 3.1 5.3 1.4 -1.9 2.3 2.0 1.7 1.8 1.5 1.1
Forced expiratory volume in 1-second (FEV1), predicted 1.2 2.4 4.1 2.0 0.6 0.4 1.2 1.6 1.9 1.9 1.8
Whole body fat-free mass 0.1 0.3 0.6 -0.4 0.6 -0.8 -0.7 -0.1 0.3 0.7 0.5
Leg fat-free mass (right) 0.1 0.5 1.4 0.4 0.3 -0.1 -0.0 0.6 0.9 1.2 1.1
Arm fat percentage (left) 0.4 1.5 2.7 0.9 -1.3 1.1 0.9 1.4 1.1 1.6 1.2
Average weekly red wine intake 0.6 0.8 2.1 -0.7 -0.9 1.4 1.4 0.7 0.3 0.7 -0.4
Handedness (chirality/laterality): Left-handed 1.0 1.1 3.2 0.6 -1.8 1.1 0.9 1.1 1.1 0.7 0.8
Mood swings 2.5 4.6 6.7 1.8 -2.5 2.6 2.6 2.3 2.0 1.7 1.3
Loneliness, isolation 1.1 1.5 2.7 1.4 -0.8 1.6 1.5 1.3 1.3 0.8 0.6
Long-standing illness, disability or infirmity 1.0 1.5 4.5 0.6 -0.8 0.0 0.4 1.4 1.6 1.3 2.1
Ever had bowel cancer screening 0.7 0.8 1.3 0.8 -0.6 1.1 1.0 0.9 1.0 0.7 0.7
Diabetes diagnosed by doctor 0.9 1.4 2.6 1.5 -1.3 0.4 0.3 1.0 1.4 1.2 1.6
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.4 3.5 -1.9 -0.1 -0.7 -0.8 -1.1 -1.3 -1.4 -1.4
Friendships satisfaction 1.5 1.9 4.1 1.5 -0.3 0.6 0.9 1.4 1.6 2.0 1.7
Qualifications: nursing, teaching 1.3 2.1 3.6 1.1 -0.2 1.0 1.6 1.9 1.5 1.8 1.6
Commuting to job workplace: Walk 0.5 0.6 1.8 0.7 -0.7 0.7 1.3 1.0 0.2 0.3 0.1
Eye problems/disorders: Cataract 1.0 1.2 2.9 -0.4 -1.7 1.3 1.5 1.1 0.7 0.7 0.3
Mouth/teeth dental problems: Mouth ulcers 1.0 1.6 4.9 -1.5 0.7 0.1 -0.2 -1.2 -1.4 -1.3 -2.2
Medication for cholesterol 0.6 1.0 5.6 0.3 2.4 -0.4 -0.3 0.1 0.7 0.7 0.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.3 1.5 6.2 -1.7 -2.5 0.0 -0.3 -0.5 -1.3 -0.6 -0.9
Back pain experienced in last month 1.1 1.6 3.9 -1.2 -0.7 -2.0 -1.5 -1.3 -1.0 -1.1 -0.7
Mineral and other dietary supplements 1.8 2.5 4.4 1.9 -0.9 1.1 1.3 1.5 2.1 1.4 1.9
Breast cancer (self-reported) 0.4 0.5 1.9 0.4 0.2 -0.3 -0.1 0.7 1.0 0.5 1.4
Asthma (self-reported) 0.6 1.3 3.2 -1.8 0.1 -1.3 -1.0 -1.3 -0.9 -0.7 -1.1
Osteoporosis (self-reported) 1.3 1.6 2.9 1.0 -1.4 1.7 1.5 1.3 1.1 1.1 0.9
Osteoarthritis (self-reported) 1.2 1.5 2.3 0.9 -1.3 1.2 1.0 1.5 1.3 1.3 1.1
Medication: Aspirin 0.8 1.1 6.5 0.1 -2.5 1.0 0.8 0.5 0.1 0.1 -0.4
Medication: Gliclazide 4.5 5.0 8.2 2.4 -0.8 2.9 2.3 2.4 2.4 2.1 2.1
Illnesses of father: None of the above (group 1) 0.7 0.9 2.2 -0.5 -1.0 1.4 1.5 1.0 0.5 0.4 0.2
Smoking status: Current 0.9 1.4 6.1 0.5 -2.5 0.6 0.7 0.9 0.9 1.1 0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.0 0.1 0.3 0.4 0.4 0.1 -0.0 -0.1 -0.3 -0.3 -0.6
Whole body water mass 0.0 0.3 0.7 -0.2 0.4 -0.6 -0.5 0.0 0.4 0.8 0.6
Leg predicted mass (right) 0.1 0.5 1.6 0.4 0.3 -0.1 0.0 0.6 0.9 1.2 1.1
Arm fat mass (left) 0.3 1.4 3.1 0.7 -1.3 0.8 0.7 1.3 1.2 1.8 1.4
Number of self-reported non-cancer illnesses 4.1 7.2 8.5 2.7 -2.9 2.7 2.5 2.9 2.8 2.3 2.6
Average weekly champagne plus white wine intake 1.1 1.5 2.9 1.7 -0.3 1.5 1.4 1.3 1.3 1.0 0.9
Miserableness 2.6 4.6 7.5 1.5 -2.7 2.7 2.7 2.4 1.6 1.6 1.3
Guilty feelings 1.9 2.8 8.1 0.7 -2.5 2.9 2.2 1.4 0.8 0.6 -0.2
Wears glasses or contact lenses 2.7 3.2 5.5 2.0 -1.1 1.0 1.4 2.0 2.3 1.6 2.3
Ever taken oral contraceptive pill 1.6 1.8 3.1 1.8 -0.6 1.6 1.4 1.2 1.6 1.4 0.9
Hearing aid user 1.4 1.5 4.0 0.4 -2.0 1.3 1.5 1.3 1.0 0.9 0.7
Mother’s age at death 0.2 0.2 0.6 0.3 0.7 0.7 0.8 0.4 0.1 -0.3 -0.2
Financial situation satisfaction 0.4 0.5 1.3 0.5 -0.9 0.6 0.5 0.6 1.1 0.1 0.8
Tinnitus: Yes, now most or all of the time 3.2 3.8 6.1 -1.8 2.5 -2.4 -2.1 -1.9 -1.6 -1.7 -1.3
Commuting to job workplace: Public transport 0.2 0.2 0.6 0.5 0.0 0.7 0.7 0.5 0.4 0.4 0.1
Eye problems/disorders: Glaucoma 1.1 1.4 2.3 -0.4 1.5 -1.2 -1.2 -1.3 -1.5 -0.8 -1.1
Medication: Blood pressure 0.3 0.6 3.4 0.1 -1.9 0.6 0.4 0.0 -0.4 -0.3 -0.6
Pain type(s) experienced in last month: Hip pain 0.6 0.8 1.9 -0.8 0.1 -1.4 -1.2 -1.0 -0.8 -0.7 -0.7
Supplements: Fish oil (including cod liver oil) 0.4 0.6 1.1 -1.0 0.4 -0.5 -0.5 -0.7 -1.1 -0.8 -1.0
High cholesterol (Self-reported) 1.0 1.9 3.1 -1.6 -0.5 -0.7 -1.2 -1.5 -1.3 -1.8 -1.7
Medication: Bendroflumethiazide 1.1 1.7 3.6 1.3 -1.5 1.9 1.4 1.3 0.9 1.0 0.7
Medication: Paracetamol 2.1 3.2 5.0 1.5 -1.3 2.1 2.1 2.2 1.4 2.0 1.4
Medication: Lisinopril 2.9 3.8 11.1 0.9 -3.3 2.9 2.3 1.4 1.2 1.1 0.2
Medication: Atorvastatin 0.2 0.3 0.9 -0.4 0.2 -0.1 0.1 -0.4 -0.4 -0.9 -0.8
Illnesses of father: High blood pressure 0.2 0.2 0.5 0.4 -0.4 0.6 -0.1 -0.4 -0.1 -0.2 -0.7
Alcohol drinker status: Never 0.4 0.5 3.1 0.5 1.8 -0.4 -0.2 -0.1 -0.5 -0.2 -0.2
Ever smoked 1.2 2.2 4.5 1.1 -2.1 1.6 1.6 1.4 1.4 1.4 1.1
Basal metabolic rate 0.1 0.3 1.1 -0.1 0.3 -0.5 -0.4 0.2 0.6 1.1 0.8
Leg fat percentage (left) 0.3 0.9 1.9 0.3 -1.4 0.8 0.5 1.0 0.8 1.3 1.0
Arm fat-free mass (left) 0.1 0.4 1.2 -0.7 0.4 -1.1 -0.9 -0.3 0.0 0.6 0.3
Number of operations (self-reported) 0.2 0.3 1.2 -0.6 0.4 -1.1 -0.7 -0.5 -0.3 -0.5 -0.2
Average weekly beer plus cider intake 4.1 5.9 9.2 -2.5 0.9 -1.7 -2.7 -2.9 -3.0 -2.2 -2.7
Irritability 2.1 3.6 8.6 1.9 -2.1 2.9 2.6 1.9 1.0 1.0 0.3
Risk taking 0.8 1.2 4.4 -0.2 -2.1 1.5 1.3 0.6 0.3 0.7 -0.3
Ever had prostate specific antigen (PSA) test 2.3 2.7 6.7 -1.0 2.6 -2.3 -2.3 -1.5 -1.1 -0.3 -0.3
Fractured/broken bones in last 5 years 1.2 1.6 2.3 -1.5 1.2 -1.2 -1.4 -1.4 -1.3 -0.9 -1.1
Age started oral contraceptive pill 0.2 0.2 0.5 -0.1 0.7 -0.6 -0.6 -0.2 0.1 0.1 0.6
Diastolic blood pressure, automated reading 0.1 0.3 1.4 0.5 0.0 1.2 0.4 0.4 0.2 0.7 -0.1
Ever depressed for a whole week 0.1 0.1 0.1 -0.2 -0.1 -0.3 -0.3 -0.3 -0.3 -0.2 -0.4
Unable to work because of sickness or disability 0.5 0.7 1.3 1.2 -0.3 0.8 0.8 1.1 0.5 0.5 0.9
Commuting to job workplace: Cycle 0.6 0.8 2.2 0.4 0.5 0.6 0.9 1.2 0.4 1.5 1.0
Myopia 1.4 2.1 3.2 -1.1 0.2 -1.1 -1.7 -1.8 -1.7 -1.5 -1.6
Vascular/heart problems diagnosed by doctor 0.8 2.2 10.6 -0.9 3.2 -1.9 -1.3 -1.0 -0.6 -0.2 -0.0
Cholesterol lowering medication 0.3 0.4 1.6 -0.5 -1.3 -0.6 -0.3 -0.4 -0.6 -0.4 -0.6
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 1.2 0.5 0.5 -0.8 -0.6 0.2 0.8 0.9 1.1
Pain experienced in last month 0.4 0.6 1.7 1.3 0.5 0.8 0.8 0.8 0.7 0.5 0.7
Supplements: Calcium 1.1 1.2 1.7 1.2 -0.2 1.2 1.0 1.2 1.1 1.2 1.3
Basal cell carcinoma (self-reported) 1.3 1.5 3.2 1.4 0.3 0.5 0.9 1.3 1.5 1.8 1.5
Heart attack/myocardial infarction (self-reported) 1.1 1.5 3.1 1.3 0.3 0.1 0.4 1.2 1.5 1.8 1.7
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 1.3 1.0 0.9 0.3 0.3 0.6 0.3 1.0 1.1
Heart disease (siblings) 0.8 1.0 1.6 1.2 -0.0 1.0 0.8 1.2 0.8 1.0 1.3
Alcohol drinker status: Previous 3.7 4.2 5.8 1.7 -2.3 2.1 2.4 2.3 1.7 2.1 1.6
Pack years of smoking 0.7 1.1 3.3 1.1 -0.3 -0.4 -0.0 0.9 1.2 1.3 1.8
Impedance of whole body 0.1 0.5 1.0 -0.8 0.7 -0.7 -0.4 -0.7 -0.6 -1.0 -0.6
Leg fat mass (left) 0.3 1.3 3.1 0.7 -1.2 0.7 0.6 1.2 1.2 1.8 1.5
Arm predicted mass (left) 0.1 0.4 1.0 -0.5 0.4 -1.0 -0.8 -0.2 0.3 0.8 0.6