[Hub]/) : Traits : Hair Pigment : ←

chr22:39,064,209-42,301,748

Best TWAS P=5.64e-16 · Best GWAS P=6.63e-15 conditioned to 2.22e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LOC100506472 0.13 0.16 bslmm 395 0.16 1.9e-18 -5.0 -5.4 6.3e-08 0.34 1.00 0.00 TRUE
2 GTEx Artery Aorta L3MBTL2 0.14 0.01 lasso 6 0.04 1.8e-03 3.9 -5.4 6.8e-08 0.09 0.02 0.92 FALSE
3 GTEx Cells Transformed fibroblasts SLC25A17 0.09 0.03 enet 10 0.06 4.2e-05 -6.3 -5.9 3.4e-09 0.06 0.01 0.99 TRUE
4 GTEx Spleen SYNGR1 0.36 0.41 lasso 2 0.36 3.4e-10 -7.7 -7.8 4.2e-15 0.47 0.00 1.00 FALSE
5 GTEx Testis SYNGR1 0.39 0.30 enet 21 0.38 3.7e-18 -7.7 -5.3 1.1e-07 0.34 0.01 0.99 TRUE
6 GTEx Whole Blood SYNGR1 0.15 0.09 lasso 5 0.09 5.4e-09 -7.1 -8.1 5.6e-16 0.67 0.08 0.92 TRUE
7 NTR Blood SYNGR1 0.03 0.03 enet 6 0.03 1.0e-10 -7.7 -7.4 1.2e-13 0.43 0.00 1.00 TRUE
8 YFS Blood SYNGR1 0.31 0.36 bslmm 371 0.38 3.9e-135 -7.7 -7.4 1.2e-13 0.53 0.00 1.00 TRUE
9 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SYNGR1 0.09 0.05 enet 3 0.06 3.9e-04 5.9 6.1 1.4e-09 -0.49 0.05 0.71 TRUE
10 The Cancer Genome Atlas Prostate Adenocarcinoma SYNGR1 0.12 0.04 lasso 4 0.03 3.5e-04 -4.1 5.4 7.6e-08 -0.46 0.09 0.15 FALSE
11 The Cancer Genome Atlas Stomach Adenocarcinoma RANGAP1 0.19 0.04 enet 10 0.05 2.8e-04 -6.5 -5.9 3.6e-09 0.10 0.00 0.93 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma L3MBTL2 0.05 0.03 enet 9 0.04 1.8e-04 -6.5 -5.3 1.2e-07 0.08 0.01 0.98 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma PDGFB 0.08 0.01 blup 59 0.03 1.1e-03 -7.8 6.7 2.6e-11 -0.61 0.00 0.91 TRUE