[Hub]/) : Traits : Tanning :

chr2:26,883,355-28,402,863

Best TWAS P=4.17e-11 · Best GWAS P=4.12e-14 conditioned to 5.25e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex IFT172 0.06 0.09 enet 16 0.09 3.9e-11 3.9 5.5 3.7e-08 -0.78 0.37 0.63 FALSE
2 GTEx Adipose Subcutaneous AC074117.10 0.06 0.04 lasso 5 0.02 4.8e-03 5.4 -5.1 2.8e-07 0.66 0.57 0.08 FALSE
3 GTEx Cells Transformed fibroblasts AC074117.10 0.21 0.19 enet 23 0.18 1.6e-13 5.4 -5.1 2.9e-07 0.65 1.00 0.00 FALSE
4 GTEx Esophagus Mucosa AC074117.10 0.12 0.14 lasso 8 0.14 2.1e-09 5.4 -5.5 3.0e-08 0.74 0.91 0.09 FALSE
5 GTEx Esophagus Muscularis NRBP1 0.07 0.04 lasso 6 0.04 1.3e-03 5.4 -6.0 1.7e-09 0.81 0.08 0.86 FALSE
6 GTEx Esophagus Muscularis AC074117.10 0.17 0.14 enet 5 0.09 6.6e-06 5.4 -5.2 1.7e-07 0.66 0.92 0.06 FALSE
7 GTEx Ovary AC074117.10 0.16 0.04 enet 9 0.05 2.0e-02 3.8 -5.6 2.6e-08 0.79 0.06 0.67 FALSE
8 GTEx Testis NRBP1 0.16 0.09 lasso 3 0.06 1.8e-03 5.4 -6.5 7.3e-11 0.82 0.02 0.96 FALSE
9 GTEx Testis AC074117.10 0.14 0.08 lasso 6 0.12 4.5e-06 4.3 -6.4 1.9e-10 0.88 0.03 0.97 FALSE
10 GTEx Vagina AC074117.10 0.14 0.04 enet 13 0.06 1.4e-02 4.2 -5.2 2.0e-07 0.74 0.12 0.36 FALSE
11 METSIM Adipose NRBP1 0.06 0.09 lasso 3 0.08 1.6e-12 5.4 -5.5 3.9e-08 0.68 0.99 0.01 FALSE
12 ROSMAP Brain Pre-frontal Cortex IFT172 0.07 0.02 blup 287 0.03 5.8e-05 4.1 5.5 5.0e-08 -0.66 0.42 0.50 FALSE
13 ROSMAP Brain Pre-frontal Cortex FTH1P3 0.04 0.01 bslmm 280 0.02 2.8e-03 5.4 -5.7 1.4e-08 0.67 0.04 0.73 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma GPN1 0.06 0.02 lasso 6 0.02 7.2e-05 -5.8 -5.7 9.9e-09 0.57 0.00 0.98 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma SNX17 0.08 0.01 blup 25 0.02 6.6e-05 3.1 5.8 8.8e-09 -0.52 0.00 0.78 FALSE
16 The Cancer Genome Atlas Glioblastoma Multiforme NRBP1 0.15 0.10 lasso 2 0.10 5.8e-04 5.4 -5.4 6.7e-08 0.67 0.00 0.72 FALSE
17 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FNDC4 0.13 0.06 lasso 2 0.05 1.1e-03 -6.7 6.6 4.2e-11 -0.95 0.00 0.91 TRUE