TWAS hub - KIF3A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0460	0.0230	7.2e-03	0.006	0.007	0.000	0.011	0.005	6.0e-02	3.7e-02	3.4e-01	1.3e-02	6.6e-02
2	GTEx	Adipose Subcutaneous	0.0820	0.0440	7.0e-03	0.075	NA	0.038	NA	0.074	1.0e-06	NA	4.5e-04	NA	1.2e-06
3	GTEx	Adrenal Gland	0.2492	0.1005	6.0e-03	-0.003	NA	0.001	NA	-0.008	4.5e-01	NA	3.0e-01	NA	8.8e-01
4	GTEx	Artery Aorta	0.1320	0.0510	1.8e-03	0.071	NA	0.075	NA	0.072	9.9e-05	NA	6.3e-05	NA	8.1e-05
5	GTEx	Artery Tibial	0.1087	0.0342	1.8e-05	0.078	NA	0.077	NA	0.085	9.6e-07	NA	1.2e-06	NA	3.2e-07
6	GTEx	Cells Transformed fibroblasts	0.1490	0.0460	1.1e-04	0.158	NA	0.149	NA	0.146	6.6e-12	NA	2.6e-11	NA	4.4e-11
7	GTEx	Esophagus Muscularis	0.3110	0.0680	2.7e-09	0.167	NA	0.184	NA	0.202	2.3e-10	NA	2.4e-11	NA	2.2e-12
8	GTEx	Heart Atrial Appendage	0.1130	0.0540	5.6e-03	-0.004	NA	0.005	NA	-0.005	5.3e-01	NA	1.8e-01	NA	6.6e-01
9	GTEx	Nerve Tibial	0.2260	0.0551	1.4e-06	0.167	NA	0.152	NA	0.153	7.1e-12	NA	6.7e-11	NA	5.3e-11
10	GTEx	Skin Sun Exposed Lower leg	0.1130	0.0450	1.0e-03	0.036	NA	0.030	NA	0.035	5.1e-04	NA	1.4e-03	NA	6.2e-04
11	METSIM	Adipose	0.0798	0.0258	4.6e-08	0.075	0.055	0.064	0.064	0.073	2.1e-11	1.1e-08	7.9e-10	6.2e-10	4.0e-11
12	TCGA	Stomach Adenocarcinoma	0.1330	0.0850	8.8e-03	-0.001	0.009	0.015	NA	0.006	4.3e-01	7.2e-02	2.9e-02	NA	1.1e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Asthma	23.2	45.7	66.0	-1.1	-7.8	1.6	-8.1	-8.1	-7.9	-7.7	-6.7	-7.8	-8.0	-7.8
Asthma (self-reported)	20.1	40.0	56.6	-1.2	-7.3	1.9	-7.5	-7.5	-7.2	-7.2	-6.4	-7.2	-7.5	-7.4
Respiratory disease	19.4	43.1	61.4	-1.6	-7.5	2.9	-7.8	-7.8	-7.7	-7.6	-6.4	-7.6	-7.8	-7.3
Allergy	13.8	31.8	47.1	1.1	6.7	-1.2	6.7	6.9	6.5	6.4	5.5	6.5	6.8	6.3
Allergy or Eczema	10.0	26.3	40.6	-0.1	-6.0	0.8	-6.2	-6.4	-6.0	-5.9	-5.1	-6.0	-6.2	-5.4
Hayfever, allergic rhinitis or eczema	9.8	21.3	33.8	0.5	-5.5	0.5	-5.5	-5.8	-5.3	-5.2	-4.9	-5.1	-5.5	-5.0
Blood Eosinophil Count	9.3	71.4	338.6	6.5	-6.1	18.4	-5.6	-7.5	-5.3	-5.4	-12.9	-5.4	-5.8	-7.9
Medication: Ventolin 100micrograms inhaler	6.9	8.9	13.0	-0.1	-3.5	1.3	-3.5	-3.6	-3.4	-3.3	-3.2	-3.3	-3.6	-3.3
Crohns Disease (2017)	6.6	14.4	22.8	-0.5	4.4	0.7	4.5	4.8	4.4	4.5	4.0	4.4	4.5	3.8
Hayfever/allergic rhinitis (self-reported)	4.8	6.4	11.3	0.5	-3.0	-0.1	-2.9	-3.4	-2.8	-2.9	-1.9	-2.8	-3.2	-3.1
Number of self-reported non-cancer illnesses	4.8	8.3	16.0	0.2	-3.1	2.2	-3.2	-3.2	-3.1	-3.1	-4.0	-3.5	-3.2	-2.7
Irritable Bowel Disease (IBD)	4.5	10.6	16.0	0.5	3.6	1.4	3.8	3.8	3.9	3.8	4.0	3.9	3.8	3.0
Chronotype (morning person)	4.3	10.0	16.4	-1.4	-4.0	-2.6	-3.2	-3.7	-3.6	-3.6	-2.5	-3.3	-3.9	-3.5
Crohns Disease (2012)	3.9	6.3	9.4	-0.3	2.9	0.9	3.1	3.0	3.0	2.9	2.9	3.0	2.9	2.3
Supplements: Glucosamine	3.9	5.0	8.2	-0.3	-2.5	-1.0	-2.8	-2.7	-2.8	-2.9	-1.6	-2.6	-2.6	-2.3
Medication: Co-codamol	3.7	4.3	6.8	-0.4	-2.2	-1.7	-2.4	-2.1	-2.6	-2.5	-1.0	-2.6	-2.5	-2.5
Wheeze or whistling in the chest in last year	3.7	6.6	10.7	-3.3	-2.8	1.6	-3.1	-2.8	-2.8	-2.7	-0.4	-2.6	-2.9	-3.2
Medication: Seretide 50 evohaler	3.7	4.2	6.9	0.7	-2.3	2.0	-2.2	-2.4	-2.1	-2.1	-2.6	-2.3	-2.3	-1.9
Reaction Time	3.5	6.7	12.3	0.4	3.5	1.8	2.8	3.0	2.9	2.9	2.1	2.8	3.3	3.0
Verbal and Numeric Reasoning (VNR)	3.3	7.9	12.0	1.8	-2.9	-1.6	-3.3	-3.4	-3.2	-3.3	-3.5	-3.1	-3.1	-2.4
Blood White Count	3.3	24.7	61.3	5.4	-5.1	1.7	-5.3	-5.1	-5.1	-5.1	-7.8	-5.0	-5.2	-4.3
Fluid intelligence score	3.3	6.8	14.9	2.5	-2.4	-0.1	-3.0	-3.0	-2.9	-3.0	-3.9	-3.1	-2.7	-1.4
Type 2 Diabetes (T2D) (2012)	3.2	3.7	6.7	-0.2	-2.6	-0.3	-2.1	-2.4	-2.0	-2.1	-2.1	-1.8	-2.4	-2.3
Had major operations	3.0	3.5	5.6	0.2	-1.7	-0.2	-2.3	-2.2	-2.3	-2.3	-1.8	-2.3	-2.1	-2.4
Happiness	2.9	3.5	6.0	-1.4	-1.8	-2.4	-1.9	-2.0	-2.0	-2.0	-0.7	-2.1	-2.0	-2.4
Exposure to tobacco smoke at home	2.9	3.3	4.9	-0.3	1.9	1.2	2.0	2.2	2.0	2.1	2.1	2.2	1.9	1.9
Loud music exposure frequency	2.9	3.2	6.1	-2.3	-1.4	-0.1	-2.4	-1.5	-2.3	-2.1	-1.9	-2.5	-1.6	-1.0
Severe depression (siblings)	2.8	3.2	5.6	-0.8	-1.8	-0.2	-2.1	-2.0	-2.1	-2.1	-2.4	-2.3	-2.0	-1.2
Number of live births	2.8	4.0	7.6	-0.5	2.2	0.6	2.4	2.8	2.4	2.5	1.0	2.5	2.5	2.0
Medication: Allopurinol	2.8	3.7	6.7	-2.6	2.4	1.4	1.8	2.2	1.8	1.9	1.9	1.6	2.2	2.2
Ever had bowel cancer screening	2.7	3.2	6.6	0.5	-2.1	-1.1	-1.9	-2.2	-1.9	-2.0	-0.2	-2.0	-2.2	-2.6
Intelligence (Savage-Jansen 2018)	2.6	8.0	11.9	1.1	-3.2	-1.6	-3.3	-3.4	-3.3	-3.3	-2.5	-3.3	-3.5	-3.0
Mean time to correctly identify matches	2.6	4.9	9.3	0.5	3.0	2.0	2.3	2.5	2.4	2.4	1.8	2.2	2.7	2.6
Father’s age at death	2.4	3.2	6.4	-0.7	2.1	-0.4	1.9	2.3	2.0	1.9	1.7	1.8	2.1	2.5
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.6	8.9	-1.3	-1.7	-0.1	-2.4	-1.8	-2.3	-2.1	-3.0	-2.5	-1.9	-1.1
Shortness of breath walking on level ground	2.4	2.8	5.7	-0.2	-1.6	0.1	-2.1	-1.6	-2.2	-2.0	-1.9	-2.4	-2.1	-1.4
Blood Platelet Count	2.3	26.9	70.1	5.4	-5.8	-1.3	-4.9	-5.8	-5.0	-4.9	-8.4	-4.8	-5.5	-5.1
Schizophrenia vs Biploar Disorder	2.2	2.9	5.5	1.3	1.6	1.2	2.2	1.8	2.1	2.2	0.8	2.3	2.0	1.3
Qualifications: College or University degree	2.2	6.9	13.0	1.1	-2.4	-2.0	-3.0	-2.9	-3.2	-3.3	-3.6	-3.3	-2.9	-1.0
Fractured/broken bones in last 5 years	2.2	2.8	6.6	0.1	1.9	2.0	1.9	1.8	1.8	1.7	0.8	1.6	1.8	2.6
Pain all over the body in last month	2.1	2.3	3.3	-0.1	-1.6	-1.8	-1.7	-1.7	-1.7	-1.6	-1.7	-1.5	-1.6	-1.8
Average weekly beer plus cider intake	2.1	3.0	4.8	-0.5	1.8	0.8	2.2	2.0	2.0	1.9	1.7	2.0	1.9	2.2
Prostate Cancer	2.0	2.8	5.4	0.4	-1.9	-1.0	-1.8	-2.3	-1.9	-2.0	-0.9	-1.9	-2.1	-2.0
Coronary Artery Disease (CAD)	2.0	2.4	4.6	0.4	1.6	1.1	1.9	2.1	2.0	2.0	0.5	2.0	1.8	1.1
Taking other prescription medications	2.0	3.1	5.6	1.3	-1.5	2.0	-1.9	-1.8	-1.7	-1.7	-2.4	-1.9	-1.8	-2.1
Age when periods started (menarche)	2.0	4.9	11.1	0.3	2.4	1.1	2.5	2.4	2.5	2.4	3.3	2.5	2.5	1.9
Long-standing illness, disability or infirmity	2.0	3.0	6.0	1.5	-1.0	2.4	-2.0	-1.4	-2.0	-1.9	-2.2	-2.2	-1.5	-0.7
Alzheimer’s Disease (in mother)	1.9	2.2	7.3	0.3	1.5	2.7	1.4	1.7	1.5	1.6	1.0	1.4	1.6	1.6
Number of incorrect matches in round	1.9	3.1	6.8	-0.6	1.6	0.1	2.3	2.0	2.2	2.2	2.6	2.0	1.8	1.3
Hair/balding pattern: Pattern 4	1.9	4.5	7.1	1.3	2.3	1.4	2.6	2.4	2.6	2.5	0.4	2.7	2.5	2.5
Gout (self-reported)	1.9	2.6	10.6	-3.3	1.7	1.4	1.2	1.5	1.1	1.2	1.8	1.0	1.5	1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.9	2.2	3.8	0.6	1.8	1.3	1.5	1.9	1.7	1.7	0.3	1.5	1.9	2.0
Tinnitus: Yes, now most or all of the time	1.9	2.2	3.8	0.2	-1.9	-1.0	-1.6	-1.9	-1.7	-1.8	-0.8	-1.6	-2.0	-1.7
Bipolar Disorder (2011)	1.8	1.8	3.1	-0.2	-1.5	0.5	-1.6	-1.5	-1.6	-1.8	-1.0	-1.7	-1.6	-1.3
Fasting Glucose	1.8	2.2	4.0	0.6	1.5	2.0	1.8	1.5	1.7	1.8	0.3	1.6	1.7	1.6
Lung FEV1/FVC ratio	1.8	9.1	16.7	3.5	2.5	-1.5	3.6	2.8	3.9	3.6	3.2	4.1	3.1	1.5
Hand grip strength (left)	1.8	4.8	16.6	-3.2	1.9	-1.6	1.9	2.1	1.9	1.8	4.1	2.0	1.9	1.6
Number of treatments/medications taken	1.8	3.3	7.5	1.0	-1.4	2.0	-2.1	-1.8	-2.0	-1.9	-2.7	-2.2	-1.8	-1.4
Family relationship satisfaction	1.8	2.2	3.5	-1.2	-1.4	-1.9	-1.6	-1.7	-1.7	-1.6	-1.2	-1.7	-1.5	-1.4
Illnesses of siblings: Diabetes	1.8	2.2	3.5	-0.7	-1.6	0.2	-1.8	-1.9	-1.7	-1.8	-1.3	-1.8	-1.7	-1.5
Height	1.7	31.9	121.6	-11.0	3.6	-3.4	4.3	4.8	4.1	4.0	10.9	4.4	3.8	3.0
Hypothyroidism (self reported)	1.7	3.9	5.5	-0.6	2.1	-1.0	2.3	2.3	2.3	2.3	2.3	2.2	2.2	1.9
Average weekly spirits intake	1.7	2.1	3.4	0.5	-1.6	-1.4	-1.5	-1.7	-1.6	-1.8	-0.6	-1.5	-1.7	-1.9
Multivitamins +/- minerals	1.7	2.2	3.7	-0.7	-1.8	-0.1	-1.8	-1.9	-1.8	-1.8	-0.6	-1.7	-1.7	-1.9
Qualifications: A levels/AS levels or equivalent	1.7	3.8	6.3	-0.5	-1.7	-2.0	-2.5	-2.1	-2.5	-2.4	-2.1	-2.5	-2.0	-1.1
Medication for cholesterol	1.7	2.5	11.3	-1.4	0.9	-1.7	1.6	1.3	1.5	1.4	3.4	1.7	1.2	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.6	6.2	0.9	1.9	0.6	2.5	1.8	2.3	2.2	1.9	2.5	2.2	2.1
Medication: Blood pressure	1.7	3.3	18.1	2.1	-0.9	2.5	-1.4	-1.2	-1.2	-1.2	-4.2	-1.6	-1.1	-0.3
Medication: Bendroflumethiazide	1.7	2.6	13.4	3.1	-0.2	2.0	-0.7	-0.6	-0.7	-0.7	-3.7	-1.1	-0.5	0.4
Commuting to job workplace: Cycle	1.7	2.1	7.1	-2.1	-1.4	-2.7	-1.2	-1.3	-1.2	-1.4	-0.6	-1.2	-1.5	-1.0
HDL Cholesterol	1.6	2.7	5.0	-2.0	-1.6	-1.1	-1.8	-1.8	-1.7	-1.7	1.0	-1.8	-1.8	-2.2
Average weekly fortified wine intake	1.5	1.8	3.6	0.1	1.1	0.6	1.8	1.3	1.8	1.5	1.0	1.9	1.5	1.5
Exposure to tobacco smoke outside home	1.5	2.0	7.5	-2.1	0.7	0.6	1.3	1.4	1.4	1.4	2.7	1.5	1.0	0.5
Rheumatoid Arthritis	1.4	1.9	3.9	-0.9	-1.9	-0.8	-1.4	-1.8	-1.4	-1.4	-0.9	-1.2	-1.6	-2.0
Hand grip strength (right)	1.4	3.8	16.2	-3.0	1.5	-1.8	1.4	1.6	1.4	1.4	4.0	1.6	1.5	1.2
Pulse wave Arterial Stiffness index	1.4	1.6	2.9	0.2	1.3	-0.3	1.7	1.7	1.6	1.7	-0.2	1.6	1.5	1.4
Triglycerides	1.3	2.1	9.3	2.6	-0.9	0.7	-1.2	-1.2	-1.1	-1.2	-3.1	-1.1	-1.0	-0.3
Ulcerative Colitis	1.3	1.8	3.2	1.2	1.5	1.8	1.3	1.3	1.5	1.3	1.5	1.2	1.4	1.5
Standing height	1.3	13.1	50.2	-7.1	2.4	-2.2	3.1	3.0	2.8	2.7	6.7	3.0	2.6	1.7
Myopia	1.3	1.9	3.2	-1.8	-1.6	-1.3	-1.4	-1.3	-1.5	-1.4	0.1	-1.5	-1.6	-1.7
Heart disease (siblings)	1.3	1.5	2.9	-1.2	0.6	1.2	1.6	1.6	1.5	1.6	1.0	1.7	1.1	0.6
Age at first live birth	1.2	2.2	3.6	0.9	-1.3	-0.8	-1.7	-1.7	-1.7	-1.8	-1.7	-1.9	-1.5	-1.4
Pulse wave peak to peak time	1.2	1.4	2.4	-0.6	-1.2	0.3	-1.5	-1.5	-1.5	-1.6	0.5	-1.5	-1.4	-1.4
Chest pain or discomfort	1.2	1.8	2.6	-0.6	-1.5	1.2	-1.4	-1.2	-1.5	-1.4	-1.3	-1.6	-1.6	-1.6
Miserableness	1.2	2.1	4.1	-0.2	-1.9	-1.5	-1.4	-2.0	-1.4	-1.5	-0.7	-1.3	-1.7	-1.9
Ulcerative Colitis (UC)	1.1	2.0	5.1	0.6	1.3	1.1	1.6	1.3	1.8	1.5	2.2	1.7	1.5	1.1
Heel T-Score	1.1	9.0	18.4	-1.0	-4.3	-1.8	-3.3	-3.1	-3.4	-3.1	-2.6	-3.2	-3.9	-3.4
Frequency of depressed mood in last 2 weeks	1.1	1.5	2.5	-0.5	-1.3	-0.6	-1.4	-1.6	-1.5	-1.5	-0.7	-1.3	-1.4	-1.4
Bilateral oophorectomy (both ovaries removed)	1.1	1.2	2.0	0.8	-0.8	-0.7	-1.4	-1.3	-1.4	-1.4	-1.3	-1.2	-1.0	-1.1
Prospective memory result	1.1	1.3	3.8	0.1	0.5	-1.1	1.4	1.0	1.5	1.3	2.0	1.6	0.9	0.2
High blood pressure (siblings)	1.1	1.6	4.9	1.5	-1.4	1.1	-1.1	-1.0	-1.1	-1.1	-2.2	-1.2	-1.3	-0.9
Comparative body size at age 10	1.1	3.1	5.8	1.6	-1.4	0.6	-2.2	-1.9	-2.2	-2.0	-2.4	-2.2	-1.8	-1.2
Number of full brothers	1.1	1.4	2.4	-0.8	1.0	1.1	1.4	1.6	1.4	1.5	0.8	1.3	1.3	1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.4	5.8	-2.4	1.3	-2.1	1.6	1.4	1.4	1.3	1.9	1.6	1.4	0.7
Average weekly red wine intake	1.1	1.6	3.0	1.5	-1.1	-1.4	-1.3	-1.7	-1.2	-1.4	-1.5	-1.2	-1.2	-0.8
Osteoarthritis (self-reported)	1.1	1.4	6.5	2.5	-0.6	-0.0	-1.2	-1.2	-1.1	-1.1	-1.6	-1.2	-0.8	-0.1
Hearing aid user	1.1	1.3	2.6	0.8	0.7	0.6	1.5	1.1	1.6	1.6	0.4	1.6	1.2	1.0
Alcohol drinker status: Previous	1.1	1.2	1.9	0.6	1.1	1.2	1.3	1.4	1.3	1.4	-0.1	1.3	1.3	1.1
Ever had hysterectomy (womb removed)	1.0	1.1	6.0	2.5	1.1	0.5	0.9	0.6	1.0	0.9	-0.2	0.9	1.1	1.0
Diabetes (father)	1.0	1.2	3.1	1.3	-1.1	1.3	-0.9	-1.2	-0.9	-1.0	-1.8	-0.9	-1.0	-1.0
Guilty feelings	1.0	1.5	3.2	-0.4	-1.5	-1.3	-1.2	-1.3	-1.3	-1.3	-0.4	-1.2	-1.4	-1.8
Alzheimer’s Disease (in father)	0.9	1.0	1.4	-0.7	-1.0	-1.2	-1.1	-1.1	-1.2	-1.1	-0.4	-1.2	-1.1	-1.0
Current tobacco smoking	0.9	1.4	2.5	0.9	1.6	1.0	1.2	1.3	1.2	1.3	0.6	1.4	1.5	1.5
Worrier / anxious feelings	0.9	1.7	3.2	1.6	1.4	0.6	1.8	1.3	1.6	1.6	0.9	1.6	1.4	1.0
Depression (self-reported)	0.9	1.0	5.7	-0.2	-0.8	1.0	-0.9	-1.0	-1.0	-0.9	-2.4	-0.9	-0.7	-0.2
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	5.2	2.3	0.2	-1.9	1.0	0.1	0.7	0.6	-1.1	0.9	0.5	0.4
Migraine (self-reported)	0.9	1.1	1.9	-0.3	-1.3	-0.8	-1.2	-1.3	-1.2	-1.3	-0.3	-1.2	-1.3	-1.4
Wears glasses or contact lenses	0.9	1.0	2.3	-0.8	-1.3	-1.3	-0.9	-1.1	-0.9	-0.9	0.2	-0.7	-1.3	-1.5
Pain type(s) experienced in last month: Hip pain	0.9	1.1	9.2	-3.0	-0.5	0.5	-0.4	-0.2	-0.4	-0.5	1.4	-0.4	-0.5	-0.9
Ever depressed for a whole week	0.9	1.2	2.9	-1.1	-0.5	0.1	-1.4	-1.1	-1.5	-1.4	-1.3	-1.7	-0.9	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	1.5	0.2	-1.1	-1.1	-1.0	-1.2	-1.2	-1.1	0.2	-1.1	-1.2	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.6	4.7	0.2	1.7	-0.0	2.1	1.3	1.8	1.5	2.2	2.0	1.9	2.0
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	2.8	-1.0	0.8	-0.6	1.6	1.3	1.6	1.5	1.7	1.6	1.2	0.8
Medication: Amlodipine	0.8	1.2	6.3	-0.3	-0.6	0.8	-1.2	-0.6	-1.0	-1.1	-2.5	-1.3	-0.8	-0.4
Emphysema/chronic bronchitis	0.8	0.9	4.6	-2.2	0.5	-0.3	0.7	0.9	0.7	0.8	1.5	0.8	0.6	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	2.2	-1.3	-0.5	-1.4	-1.2	-0.5	-1.2	-1.1	-0.6	-1.5	-0.8	-0.5
Eye problems/disorders: Cataract	0.8	1.0	2.2	1.5	0.8	1.2	0.8	0.9	1.0	1.0	-0.7	0.8	0.9	1.4
Smoking status: Current	0.8	1.3	2.2	1.1	1.5	0.7	1.2	1.1	1.1	1.2	0.6	1.3	1.4	1.5
Eye problems/disorders: Glaucoma	0.8	1.0	3.6	-1.9	-1.0	0.7	-0.8	-0.4	-0.8	-0.7	-1.7	-0.8	-0.7	-0.6
Body Mass Index (BMI) (2010)	0.7	1.0	2.1	-0.3	1.4	1.4	1.0	1.1	1.0	1.1	0.4	0.8	1.2	1.0
Hearing difficulty/problems: Yes	0.7	1.1	5.4	-2.3	-0.6	-0.2	-1.1	-0.5	-1.1	-0.9	0.1	-1.3	-0.9	-1.1
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.7	0.6	-1.0	-1.1	-0.8	-0.6	-0.7	-0.8	0.7	-0.7	-0.9	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	1.8	-0.6	-0.9	-0.1	-1.3	-1.2	-1.3	-1.2	-0.2	-1.3	-1.2	-1.0
Medication: Lansoprazole	0.7	0.8	4.8	-2.2	-1.0	-0.4	-0.8	-0.5	-0.7	-0.6	-0.2	-0.8	-0.9	-0.9
Birth weight of first child	0.7	1.2	2.7	-0.7	1.4	0.2	1.1	1.1	1.1	1.1	1.2	0.9	1.4	1.6
Pulse wave reflection index	0.7	0.8	1.8	0.4	0.4	0.8	1.2	0.7	1.3	1.2	-1.0	1.3	0.9	0.2
Glaucoma (self-reported)	0.7	0.8	5.9	-2.4	0.0	1.4	0.4	0.7	0.4	0.5	-0.6	0.5	0.5	0.3
Neck or shoulder pain in last month	0.7	1.0	2.7	-1.3	-1.5	-0.6	-0.7	-1.0	-0.9	-0.9	-0.4	-0.6	-1.1	-1.6
Pulse rate, automated reading	0.7	2.2	4.0	2.0	-0.9	-1.3	-1.8	-1.7	-1.8	-1.8	-1.6	-1.6	-1.3	-0.6
Comparative height size at age 10	0.7	4.1	29.1	-5.4	1.0	-1.1	0.8	1.0	0.8	0.7	3.7	0.7	0.8	0.8
Hypertension (Self-reported)	0.7	1.8	10.4	1.9	-0.4	2.6	-0.3	-0.3	-0.3	-0.3	-3.2	-0.6	-0.4	0.3
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.8	-0.8	-1.2	-1.4	-1.0	-0.9	-1.1	-0.9	-0.5	-0.9	-1.2	-1.7
Worry (Nagel 2018)	0.6	1.2	2.9	0.3	1.0	-0.2	1.7	1.1	1.5	1.6	0.4	1.6	1.2	1.0
Major Depression (MDD)	0.6	0.7	3.3	0.8	0.6	1.5	-0.3	-0.2	-0.5	-0.1	-0.6	-0.8	0.0	1.8
Age at First Birth	0.6	0.9	2.2	0.1	-0.8	0.0	-1.5	-1.2	-1.2	-1.5	-0.7	-1.3	-0.8	-0.4
Primary Biliary Cirrhosis	0.6	0.9	2.5	1.6	1.1	1.4	0.7	0.8	0.8	0.7	0.1	0.8	1.0	1.1
Lung FVC	0.6	3.3	10.9	3.3	-1.1	0.4	-1.7	-2.3	-1.9	-2.1	-2.4	-1.9	-1.4	-0.1
Medication for hormone replacement therapy	0.6	0.6	2.3	0.8	-0.6	0.8	-0.9	-0.4	-0.8	-0.7	-1.5	-0.8	-0.7	-0.6
Supplements: Zinc	0.6	0.7	1.4	0.5	-0.8	0.7	-0.9	-1.0	-0.9	-1.0	-0.0	-1.0	-1.0	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	3.7	-0.8	-1.7	-0.7	-1.2	-1.2	-1.2	-1.1	-0.1	-1.2	-1.5	-1.9
High blood pressure	0.6	1.7	10.2	1.6	0.1	2.7	-0.1	0.1	0.0	-0.0	-3.2	-0.4	-0.0	0.7
Hair/balding pattern: Pattern 2	0.6	0.8	5.9	-2.4	-0.3	-1.4	-0.3	-0.1	-0.3	-0.2	1.0	-0.2	-0.3	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	4.2	0.1	-2.0	-0.5	-1.0	-1.4	-1.0	-0.9	-0.0	-0.9	-1.5	-2.0
Falls in the last year	0.6	0.8	2.4	-0.7	0.2	0.5	1.3	0.8	1.2	1.2	0.3	1.5	0.8	0.3
Hair/balding pattern: Pattern 3	0.6	1.0	6.4	2.5	-0.2	1.8	-0.3	-0.5	-0.2	-0.3	-0.7	-0.4	-0.3	-0.7
Breastfed as a baby	0.6	0.7	1.8	-0.4	0.8	-0.3	1.2	1.0	0.9	0.9	1.3	0.9	0.9	0.1
Health satisfaction	0.6	0.7	4.5	0.1	-0.3	0.0	-0.9	-0.3	-0.9	-0.8	-2.1	-1.1	-0.6	-0.2
Eye problems/disorders: None of the above	0.6	0.7	2.0	-0.3	-0.7	-1.4	-0.6	-1.3	-0.9	-1.0	0.1	-0.6	-0.8	-1.1
Illnesses of father: Heart disease	0.6	0.9	4.9	-2.2	-1.0	0.3	-0.8	-0.5	-0.8	-0.9	-0.4	-0.9	-0.9	-0.4
Friendships satisfaction	0.6	0.8	1.6	-1.1	-0.6	-0.8	-1.0	-0.8	-1.1	-1.1	-0.7	-1.3	-0.8	-0.4
Vascular/heart problems diagnosed by doctor	0.6	1.7	9.1	-1.1	-0.4	-3.0	-0.3	-0.4	-0.3	-0.3	3.0	0.1	-0.3	-1.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	4.8	1.4	0.5	2.2	-0.1	0.2	-0.1	-0.2	-0.4	-0.3	0.2	0.9
Sitting height	0.5	3.6	22.1	-4.7	1.1	-1.6	0.9	1.0	0.7	0.8	3.6	0.7	0.9	0.6
Had menopause	0.5	0.6	1.3	-0.9	0.8	1.0	0.5	1.1	0.5	0.7	0.5	0.3	0.7	1.0
Had other major operations	0.5	0.6	1.4	0.6	0.6	0.7	1.2	0.6	1.0	1.0	0.1	1.0	0.8	0.5
Qualifications: None of the above	0.5	1.1	2.3	0.4	0.8	0.0	1.3	0.9	1.4	1.5	1.3	1.5	1.1	0.1
Illnesses of siblings	0.5	0.8	5.4	-0.1	0.5	-2.3	0.1	0.1	0.2	0.2	1.8	0.3	0.3	0.1
Impedance of arm (right)	0.5	2.4	6.9	0.8	1.1	-0.4	2.2	1.5	2.0	1.8	2.6	2.1	1.4	0.4
Noisy workplace	0.5	0.7	3.2	-1.8	0.6	-0.3	0.7	0.9	0.6	0.7	1.3	0.4	0.5	0.6
Lung cancer (father)	0.5	0.5	1.1	-1.1	-0.8	-0.3	-0.8	-0.5	-0.9	-0.7	-0.5	-0.8	-0.9	-0.8
Birth weight	0.5	1.0	5.1	-0.5	1.2	-0.4	0.9	1.0	0.8	1.0	2.3	0.8	0.9	0.7
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.7	1.3	0.8	-0.5	0.9	0.6	0.7	0.7	0.7	0.8	0.8	0.9
Leg pain on walking	0.5	0.6	1.6	0.3	0.9	0.9	0.8	1.3	0.9	1.0	-0.3	0.6	0.8	0.8
Loneliness, isolation	0.5	0.7	1.2	-0.2	-0.7	-1.1	-0.9	-1.1	-1.1	-1.0	-0.4	-1.0	-0.8	-0.9
Qualifications: nursing, teaching	0.5	0.8	2.6	-1.2	0.0	-0.4	-1.3	-0.5	-1.2	-1.2	0.3	-1.6	-0.6	-0.6
Back pain experienced in last month	0.5	0.7	2.4	1.6	0.5	1.2	0.6	0.0	0.6	0.6	1.3	0.7	0.5	0.7
Osteoporosis (self-reported)	0.5	0.6	1.8	-0.1	0.9	1.4	0.7	0.5	0.6	0.7	1.2	0.6	0.6	0.8
Irritability	0.5	0.9	1.6	-0.2	-0.7	-1.3	-1.2	-1.1	-1.2	-1.1	-0.3	-1.2	-1.0	-0.8
Risk taking	0.5	0.7	3.2	-1.8	0.4	0.9	0.5	1.1	0.7	0.9	-0.3	0.7	0.7	0.2
Diastolic blood pressure, automated reading	0.5	1.6	8.3	2.9	-1.2	0.6	-0.5	-1.3	-0.5	-0.8	-2.1	-0.4	-1.0	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.6	1.1	-0.3	1.6	-0.1	-0.3	0.0	-0.0	-1.5	-0.0	-0.2	-0.6
Supplements: Calcium	0.5	0.6	4.0	-1.5	-0.2	2.0	-0.3	-0.3	-0.3	-0.3	0.2	-0.3	-0.2	-0.3
Depression (Nagel 2018)	0.4	0.6	1.2	-0.7	-0.6	-0.1	-1.1	-0.8	-1.1	-1.0	0.1	-1.0	-0.9	-0.9
Cardiovascular Disease	0.4	1.4	4.9	1.4	-1.1	1.6	-0.8	-1.2	-0.8	-1.0	-2.2	-1.0	-1.1	-0.2
Sensitivity / hurt feelings	0.4	0.6	1.6	1.3	-0.7	-0.8	-0.7	-1.0	-0.8	-0.8	-0.1	-0.7	-0.8	-1.0
Vitamin and mineral supplements	0.4	0.6	1.1	-0.3	0.8	-0.7	1.0	0.9	0.9	0.9	0.5	1.0	0.8	0.5
Leg fat-free mass (left)	0.4	2.1	16.4	-4.0	1.1	-0.4	0.4	1.0	0.5	0.4	2.2	0.4	0.8	0.9
Maternal smoking around birth	0.4	0.6	4.8	-2.2	-0.4	1.2	0.0	0.0	0.1	0.1	0.6	0.4	-0.1	-0.0
Medication: Levothyroxine sodium	0.4	0.7	1.6	0.0	0.8	-0.4	0.9	0.9	0.9	1.0	1.3	1.1	0.9	1.1
Leg predicted mass (left)	0.4	2.0	16.5	-4.1	1.0	-0.4	0.2	0.8	0.3	0.3	2.0	0.2	0.6	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.6	-0.8	0.8	0.3	0.9	0.9	0.8	0.8	1.2	0.9	0.8	0.8
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.5	0.7	-0.0	0.5	-0.8	-0.6	-1.0	-0.7	-1.2	-1.2	-0.5	-0.0
Financial difficulties in last 2 years	0.4	0.5	0.9	0.9	0.6	-0.7	0.9	0.6	0.8	0.8	0.7	0.9	0.7	0.4
Trunk fat-free mass	0.4	2.2	20.7	-4.5	0.7	-0.7	0.3	0.8	0.3	0.3	1.9	0.3	0.5	0.6
Alcohol intake versus 10 years previously	0.4	0.6	4.7	-2.2	-0.2	-0.3	-0.2	0.1	-0.2	0.0	1.4	-0.4	-0.1	-0.3
Pulse rate	0.4	0.6	2.0	0.8	-0.3	-1.4	-1.0	-0.6	-1.0	-0.9	-0.3	-0.8	-0.6	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.9	-0.4	-0.5	-1.4	0.3	-0.0	0.2	0.1	1.3	0.4	-0.1	-1.3
Trunk predicted mass	0.4	2.2	20.7	-4.5	0.6	-0.8	0.2	0.7	0.2	0.2	1.9	0.2	0.4	0.5
Tense / ‘highly strung’	0.4	0.7	1.4	-1.2	0.5	-0.3	1.0	0.7	1.0	1.0	1.0	1.1	0.8	0.0
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.6	-1.2	-0.2	-0.6	-1.0	-0.7	-1.2	-1.0	-0.0	-1.1	-0.5	-0.0
Leg fat percentage (right)	0.4	1.3	2.3	0.4	-1.3	1.4	-1.2	-1.3	-1.1	-1.1	-1.2	-1.1	-1.3	-1.5
Heart disease (mother)	0.4	0.5	0.9	0.5	0.5	-0.0	0.9	0.7	0.9	0.9	0.6	0.9	0.8	0.9
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.0	0.2	-0.6	0.3	-1.0	-0.9	-0.8	-0.8	-0.4	-1.0	-0.9	-0.6
Supplements: Vitamin C	0.4	0.4	1.1	1.1	-0.5	-1.0	-0.6	-0.8	-0.4	-0.6	-0.5	-0.6	-0.5	-0.6
Whole body fat-free mass	0.4	2.0	18.4	-4.3	0.8	-0.6	0.2	0.8	0.2	0.2	1.9	0.2	0.5	0.6
Mineral and other dietary supplements	0.4	0.6	2.6	-0.3	0.6	-1.6	0.7	0.7	0.6	0.7	0.8	0.7	0.6	0.7
Whole body water mass	0.4	2.1	19.3	-4.4	0.8	-0.5	0.2	0.8	0.3	0.2	2.0	0.2	0.6	0.6
Leg fat percentage (left)	0.4	1.5	2.5	1.2	-1.2	1.6	-1.3	-1.3	-1.2	-1.1	-1.4	-1.1	-1.3	-1.4
Unable to work because of sickness or disability	0.4	0.5	1.0	-0.3	0.9	0.8	0.6	1.0	0.8	0.8	0.1	0.7	0.9	0.6
Basal cell carcinoma (self-reported)	0.4	0.4	0.9	-0.6	-0.5	0.8	-0.7	-0.6	-0.7	-0.7	-0.7	-0.6	-0.5	-1.0
Impedance of whole body	0.4	1.9	6.8	1.0	0.5	-0.5	2.0	0.9	1.7	1.5	2.6	2.0	1.0	0.1
Bipolar Disorder (2018)	0.3	0.4	1.6	-0.1	0.3	1.3	-0.5	-0.1	-0.6	-0.7	-1.1	-0.9	-0.1	0.4
Depressed Affect (Nagel 2018)	0.3	0.6	1.6	-0.3	-0.7	-1.3	-0.8	-0.9	-0.7	-0.7	-0.7	-0.8	-0.8	-1.1
HbA1C	0.3	0.3	0.5	0.2	0.6	0.5	0.6	0.6	0.6	0.7	0.7	0.6	0.6	0.3
LDL Cholesterol	0.3	0.5	1.8	-0.2	0.4	0.1	0.7	0.9	0.7	0.8	1.3	0.7	0.6	1.0
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.2	0.4	-0.6	-1.1	-0.6	-0.4	-0.6	-0.5	-0.7	-0.6	-0.6	-0.2
Diabetes (mother)	0.3	0.4	3.0	0.7	-0.1	1.7	0.4	0.0	0.3	0.3	0.2	0.5	0.2	-0.3
Serious illness, injury or assault to yourself	0.3	0.3	0.7	-0.7	-0.4	-0.4	-0.8	-0.3	-0.8	-0.7	-0.4	-0.7	-0.5	-0.3
Nervous feelings	0.3	0.6	1.5	0.6	-1.1	-0.5	-0.4	-0.9	-0.5	-0.5	-1.2	-0.4	-0.9	-1.0
Medication: Ramipril	0.3	0.4	2.4	1.5	0.1	0.5	0.3	0.0	0.3	0.2	-1.2	0.2	0.1	0.3
Time employed in main current job	0.3	0.3	1.8	1.4	0.1	0.7	0.6	0.3	0.6	0.5	0.2	0.6	0.3	-0.3
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	2.2	-0.1	0.7	-0.9	1.3	0.6	1.0	0.8	1.5	1.4	1.0	1.3
Illnesses of mother	0.3	0.3	1.9	-0.4	0.4	-1.4	0.7	0.4	0.5	0.4	0.5	0.6	0.4	0.1
Impedance of arm (left)	0.3	1.4	5.6	0.7	0.6	-0.8	1.6	0.8	1.4	1.2	2.4	1.5	0.9	0.3
Medication: Paracetamol	0.3	0.5	3.8	-0.5	-0.4	-0.7	-0.1	-0.3	-0.1	-0.3	2.0	0.1	-0.2	-1.0
Arm fat-free mass (right)	0.3	1.5	15.3	-3.9	0.1	-0.4	-0.2	0.1	-0.3	-0.3	1.5	-0.2	-0.1	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.8	1.0	0.3	1.4	-0.4	-0.2	-0.5	-0.4	-0.7	-0.7	-0.1	0.6
Medication: Ibuprofen	0.3	0.3	1.6	0.0	-0.1	-0.9	0.1	0.2	0.1	0.2	1.1	0.2	-0.0	-1.3
Medication: Omeprazole	0.3	0.3	1.8	1.0	0.1	1.4	0.4	0.1	0.4	0.3	-0.4	0.5	0.2	-0.6
Arm predicted mass (right)	0.3	1.5	15.2	-3.9	0.2	-0.5	-0.2	0.2	-0.2	-0.2	1.6	-0.2	0.0	0.3
Suffer from ‘nerves’	0.3	0.5	3.7	-1.9	0.2	-0.6	0.6	0.4	0.4	0.5	0.6	0.6	0.4	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.9	0.3	0.3	-0.8	0.8	0.5	0.9	0.7	0.1	1.0	0.6	0.4
Smoking status: Previous	0.3	0.4	1.2	-0.1	-0.4	1.1	-0.7	-0.5	-0.6	-0.5	-0.8	-0.8	-0.4	-0.7
Leg fat-free mass (right)	0.3	1.6	13.3	-3.6	1.0	-0.4	0.1	0.7	0.2	0.2	1.8	0.2	0.6	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	1.7	1.3	-0.3	0.2	-0.3	-0.1	-0.3	-0.3	-1.3	-0.3	-0.3	-0.6
Medication: Aspirin	0.3	0.4	2.7	-0.3	0.8	1.6	0.2	0.6	0.4	0.5	-0.1	0.2	0.6	0.1
Illnesses of father: None of the above (group 1)	0.3	0.4	3.2	-0.4	0.1	-1.8	-0.2	-0.1	-0.0	0.1	0.5	0.0	-0.0	-1.2
Leg predicted mass (right)	0.3	1.6	14.0	-3.7	0.9	-0.3	0.2	0.8	0.2	0.2	1.7	0.2	0.6	0.7
Commuting to job workplace: Public transport	0.3	0.3	1.6	1.1	-0.2	-0.5	0.3	-0.4	0.1	-0.0	1.3	0.5	-0.1	-0.1
Supplements: Fish oil (including cod liver oil)	0.3	0.3	0.9	0.9	-0.6	0.7	-0.5	-0.5	-0.5	-0.6	-0.5	-0.5	-0.6	-0.7
High cholesterol (Self-reported)	0.3	0.5	1.8	-1.1	-0.4	-1.1	-0.4	-0.5	-0.4	-0.6	1.3	-0.4	-0.5	-0.3
Medication: Paracetamol	0.3	0.4	1.7	-0.3	-0.4	-0.4	-0.5	-0.6	-0.5	-0.6	1.1	-0.5	-0.5	-1.3
Medication: Atorvastatin	0.3	0.4	0.8	-0.5	0.8	-0.9	0.5	0.7	0.4	0.5	0.9	0.5	0.6	0.8
Alcohol drinker status: Never	0.3	0.4	1.4	-1.2	0.0	1.2	-0.4	0.1	-0.3	-0.1	-0.9	-0.6	-0.1	0.5
Basal metabolic rate	0.3	1.9	17.1	-4.1	0.7	-0.4	0.3	0.7	0.3	0.3	2.0	0.3	0.5	0.5
Arm fat-free mass (left)	0.3	1.6	15.7	-4.0	0.5	-0.3	0.3	0.6	0.2	0.2	1.6	0.2	0.4	0.4
Age started oral contraceptive pill	0.3	0.4	0.9	0.4	0.8	-0.9	0.6	0.9	0.5	0.6	0.5	0.5	0.6	0.9
Arm predicted mass (left)	0.3	1.5	15.5	-3.9	0.2	-0.4	0.0	0.4	0.0	-0.0	1.6	0.1	0.1	0.1
Bipolar Disorder or Schizophrenia	0.2	0.5	1.7	0.2	0.1	0.9	-1.0	-0.3	-1.0	-0.9	-0.5	-1.3	-0.3	0.7
Alzheimer’s Disease (including proxy)	0.2	0.3	1.4	-0.7	0.4	1.2	0.2	0.4	0.2	0.4	0.5	0.2	0.4	0.4
Breast Cancer	0.2	0.4	2.3	-0.8	0.2	1.1	0.1	0.6	0.1	0.3	-1.5	-0.1	0.1	0.1
Mean Putamen Volume	0.2	0.2	1.6	-0.6	0.1	0.5	0.4	0.2	0.3	0.3	1.3	0.4	0.2	-0.3
Lupus	0.2	0.3	2.7	1.6	-0.1	0.5	-0.2	-0.2	-0.1	-0.2	0.0	0.2	-0.0	-0.6
Schizophrenia (2014)	0.2	0.5	1.7	1.3	0.1	1.1	-0.7	-0.3	-0.5	-0.5	-0.6	-0.8	-0.1	0.8
BMI	0.2	1.1	4.6	0.4	-0.5	1.6	-1.2	-0.8	-0.9	-0.8	-2.1	-1.0	-0.6	-0.5
Waist Hip Ratio (WHR)	0.2	0.7	2.6	1.4	-0.4	0.6	0.6	-0.5	0.4	-0.1	1.4	0.7	-0.2	-1.6
Systolic Blood Pressure	0.2	0.8	3.3	1.6	-1.2	-0.3	-0.2	-0.8	-0.2	-0.5	-1.8	-0.1	-0.8	-0.6
Smoking Status	0.2	0.4	0.8	0.8	0.6	0.9	0.6	0.4	0.5	0.6	-0.4	0.8	0.7	0.4
Relative age of first facial hair	0.2	0.3	1.1	-1.0	0.3	1.0	0.2	0.2	0.1	0.4	-1.1	-0.1	0.3	0.3
Medication: Metformin	0.2	0.3	1.9	0.6	-0.2	0.5	-0.3	0.1	-0.2	-0.1	-1.4	-0.3	-0.3	-0.6
Pack years adult smoking proportion	0.2	0.3	2.6	0.7	0.1	1.6	0.3	0.2	0.3	0.1	0.4	0.4	0.3	0.4
Impedance of leg (right)	0.2	1.0	3.3	0.4	-0.4	-0.4	1.5	0.4	1.2	1.1	1.8	1.5	0.3	-0.5
Townsend deprivation index at recruitment	0.2	0.2	1.4	0.2	-0.3	0.9	-0.2	-0.5	-0.3	-0.3	-1.2	-0.2	-0.1	-0.2
Relative age voice broke	0.2	0.3	1.0	-0.7	1.0	0.3	0.3	0.6	0.3	0.5	0.1	0.1	0.6	0.7
Qualifications: CSEs or equivalent	0.2	0.2	1.3	-1.1	-0.2	-0.1	0.2	-0.1	0.2	0.1	0.2	0.3	0.1	-1.1
Stomach or abdominal pain in last month	0.2	0.2	1.1	-0.4	0.1	1.1	0.7	0.3	0.5	0.4	0.3	0.5	0.4	0.2
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	2.0	-1.4	0.0	0.0	-0.2	0.3	-0.3	-0.2	1.1	-0.3	-0.1	0.2
Medication: Atenolol	0.2	0.2	1.7	0.7	-0.0	0.1	-0.0	0.2	-0.0	0.1	-1.3	-0.2	-0.1	0.5
High blood pressure (mother)	0.2	0.3	1.2	-0.3	0.3	1.1	-0.7	0.0	-0.6	-0.4	-0.5	-1.1	-0.3	0.1
Body mass index (BMI)	0.2	1.0	2.6	0.5	-0.6	1.2	-1.3	-0.9	-1.1	-1.0	-1.6	-1.1	-0.9	-0.7
Impedance of leg (left)	0.2	0.7	1.7	1.3	-0.5	-0.2	1.3	0.2	0.9	0.9	1.3	1.3	0.2	-0.7
Past tobacco smoking	0.2	0.3	0.7	-0.6	0.3	-0.5	0.7	0.5	0.7	0.5	0.8	0.7	0.4	0.4
Heart attack	0.2	0.3	0.7	-0.7	0.2	0.4	0.8	0.8	0.7	0.8	0.0	0.6	0.4	-0.2
Weight	0.2	0.9	7.5	-2.7	0.5	0.2	0.2	0.5	0.3	0.3	1.5	0.3	0.3	0.1
Arm fat percentage (right)	0.2	0.8	3.7	0.7	-0.5	1.9	-0.9	-0.7	-0.7	-0.7	-0.9	-0.8	-0.7	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.8	0.8	-0.3	-0.9	-0.6	-0.6	-0.5	-0.6	0.1	-0.6	-0.4	-0.9
Length of working week for main job	0.2	0.2	0.7	-0.9	-0.7	-0.4	-0.2	-0.3	-0.2	-0.2	0.1	-0.0	-0.6	-0.3
Blood clot in the leg (DVT)	0.2	0.3	2.0	-1.4	0.2	0.8	-0.0	0.6	0.2	0.2	-0.0	0.1	0.2	0.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.3	-0.1	0.9	0.2	0.4	0.4	0.3	0.3	1.1	0.3	0.6	0.6
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.8	0.3	-0.1	1.3	0.2	-0.1	0.2	0.1	0.6	0.3	0.1	0.1
Forced vital capacity (FVC), Best measure	0.2	0.6	2.2	-1.1	0.8	0.2	0.8	0.3	0.4	0.2	1.0	0.5	0.8	1.5
Number of children fathered	0.2	0.3	0.7	0.8	0.5	0.6	0.3	0.5	0.6	0.6	0.7	0.4	0.4	0.4
Medication for pain relief, constipation, heartburn	0.2	0.3	1.8	0.5	0.4	-0.3	0.2	0.4	0.2	0.2	-0.9	0.2	0.3	1.3
Medication: Blood pressure	0.2	0.3	2.3	0.3	-0.0	0.7	0.4	0.6	0.5	0.5	-1.5	0.4	0.3	0.2
Leg fat mass (right)	0.2	0.6	1.2	-1.1	-0.8	0.9	-0.9	-0.7	-0.8	-0.7	-0.1	-0.7	-0.8	-1.0
Alcohol intake frequency.	0.2	0.6	3.3	-1.8	0.2	1.3	-0.1	0.7	0.0	0.4	-0.4	-0.4	0.2	0.9
Overall health rating	0.2	0.5	1.5	0.7	-0.4	1.2	-0.8	-0.8	-0.6	-0.5	-0.3	-0.8	-0.5	-0.7
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.3	-1.1	-0.0	0.4	-0.5	0.2	-0.3	-0.3	-0.3	-0.6	-0.2	0.7
Medication: Aspirin	0.2	0.3	2.7	-0.5	0.6	1.6	0.0	0.4	0.2	0.3	-0.1	-0.0	0.4	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.5	-0.5	0.2	0.7	0.5	0.6	0.5	0.6	0.4	0.5	0.2	-0.2
Arm fat percentage (left)	0.2	0.9	2.9	0.7	-0.7	1.7	-1.1	-0.9	-0.9	-0.9	-1.1	-1.0	-0.9	-0.9
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.8	0.8	-0.6	-0.6	-0.3	-0.9	-0.4	-0.5	-0.5	-0.3	-0.6	-0.4
Commuting to job workplace: Walk	0.2	0.2	0.9	0.9	-0.5	-0.2	-0.2	-0.7	-0.3	-0.3	0.1	-0.0	-0.4	-1.0
Breast cancer (self-reported)	0.2	0.3	1.0	-0.0	0.1	-0.3	0.7	0.1	0.7	0.5	1.0	1.0	0.4	-0.2
Medication: Gliclazide	0.2	0.2	0.9	0.9	0.6	0.4	0.0	0.4	0.0	0.0	-0.5	-0.0	0.3	0.5
Ever taken oral contraceptive pill	0.2	0.2	0.9	0.5	0.4	0.2	0.2	0.4	0.2	0.4	0.6	0.3	0.4	1.0
Mother’s age at death	0.2	0.3	0.7	-0.4	-0.3	0.1	-0.7	-0.2	-0.6	-0.6	-0.8	-0.8	-0.4	-0.3
Pain experienced in last month	0.2	0.3	0.8	-0.3	0.8	-0.3	0.3	0.7	0.5	0.5	0.3	0.2	0.6	0.9
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.9	-0.9	-0.2	0.0	0.6	0.6	0.5	0.5	-0.2	0.5	0.1	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	1.5	-1.2	0.3	0.8	0.0	0.6	0.2	0.2	-0.3	0.1	0.3	0.1
Pack years of smoking	0.2	0.2	2.0	0.7	-0.3	1.4	-0.1	-0.1	-0.1	-0.3	0.2	-0.1	-0.2	0.1
Neuroticism (Nagel 2018)	0.1	0.2	1.2	0.0	-0.2	-1.1	-0.2	-0.5	-0.2	-0.2	-0.0	-0.2	-0.2	-0.5
Schizophrenia (2018)	0.1	0.3	1.0	0.3	-0.1	0.1	-0.9	-0.3	-0.8	-0.6	0.3	-1.0	-0.3	0.6
Ovarian Cancer	0.1	0.2	1.5	-0.3	0.2	1.2	-0.1	0.1	-0.4	-0.2	-0.2	-0.3	-0.0	-0.1
Neuroticism (2016)	0.1	0.1	0.5	0.0	0.1	-0.6	0.1	0.0	0.4	0.3	-0.7	0.4	0.3	0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.7	-0.1	-0.1	0.8	-0.4	0.2	-0.1	-0.1	-0.8	-0.4	-0.2	-0.3
Angina	0.1	0.1	0.9	-1.0	-0.2	0.4	0.3	0.2	0.2	0.3	0.3	0.2	-0.1	-0.1
Trunk fat percentage	0.1	0.3	1.8	0.1	0.2	1.3	0.0	0.0	0.2	0.1	1.0	0.2	0.1	-0.4
Fed-up feelings	0.1	0.2	0.7	-0.0	-0.3	-0.6	0.1	-0.2	0.1	0.1	0.8	0.4	-0.1	-0.8
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.6	0.2	0.5	0.3	0.2	0.1	0.0	0.2	0.8	0.1	0.3	0.1
Chronic bronchitis/emphysema (father)	0.1	0.1	0.9	0.3	-0.4	-0.0	-0.1	-0.1	-0.2	-0.0	-0.9	-0.1	-0.3	0.1
Trunk fat mass	0.1	0.4	2.1	-1.2	0.3	0.9	-0.0	0.2	0.1	0.1	1.4	0.1	0.1	-0.3
Alcohol usually taken with meals	0.1	0.2	0.9	0.4	-0.1	-0.9	-0.5	-0.2	-0.4	-0.5	-0.5	-0.6	-0.3	-0.5
Forced vital capacity (FVC)	0.1	0.3	1.2	-1.1	0.1	-0.7	0.3	-0.2	-0.1	-0.3	0.5	0.1	0.2	1.0
Mouth/teeth dental problems	0.1	0.2	0.7	-0.9	0.3	0.6	-0.6	0.1	-0.4	-0.4	-0.1	-0.7	-0.1	0.2
Diabetes (self-reported)	0.1	0.2	0.5	-0.6	-0.1	0.6	0.2	0.5	0.4	0.4	-0.7	0.2	0.0	-0.7
Medication: Simvastatin	0.1	0.2	1.0	-0.8	-0.0	-0.1	0.2	0.0	0.3	0.1	1.0	0.3	0.1	-0.3
Neuroticism score	0.1	0.2	0.9	0.4	-0.3	-1.0	-0.2	-0.5	-0.4	-0.3	-0.2	-0.4	-0.3	-0.6
Mouth/teeth dental problems: Dentures	0.1	0.2	0.8	-0.5	-0.6	0.9	-0.5	-0.4	-0.4	-0.5	-0.1	-0.4	-0.5	-0.5
Arm fat mass (right)	0.1	0.3	1.2	-0.9	-0.2	1.1	-0.7	-0.3	-0.5	-0.5	0.1	-0.5	-0.4	-0.6
Peak expiratory flow (PEF)	0.1	0.3	0.9	-1.0	-0.6	-0.8	-0.3	-0.4	-0.4	-0.5	0.9	-0.2	-0.5	-0.7
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.3	-0.3	0.6	0.2	0.2	0.5	0.2	0.3	-0.1	0.1	0.4	0.5
Headache pain in last month	0.1	0.2	1.6	-0.3	0.3	-1.3	0.4	0.2	0.3	0.3	0.0	0.2	0.3	0.3
Body fat percentage	0.1	0.4	2.1	0.3	-0.5	1.5	-0.6	-0.6	-0.4	-0.4	0.0	-0.4	-0.6	-0.9
Worry too long after embarrassment	0.1	0.2	2.4	1.6	0.4	-0.1	0.3	-0.1	0.1	-0.0	0.5	-0.1	0.1	0.2
Angina (self-reported)	0.1	0.1	0.5	-0.7	-0.6	0.1	-0.1	-0.1	-0.1	-0.0	-0.0	-0.1	-0.5	-0.5
Whole body fat mass	0.1	0.4	1.4	-1.2	-0.3	0.9	-0.6	-0.3	-0.4	-0.4	0.6	-0.4	-0.4	-0.8
Age at last live birth	0.1	0.2	0.5	0.5	0.3	-0.7	0.6	0.6	0.6	0.5	0.2	0.4	0.3	0.1
Knee pain experienced in last month	0.1	0.1	0.4	0.4	0.1	0.5	-0.3	-0.1	-0.3	-0.3	0.6	-0.4	-0.1	0.2
Mood swings	0.1	0.3	1.2	0.2	-0.4	-0.3	-0.3	-0.6	-0.5	-0.4	-1.1	-0.5	-0.4	-0.6
Diabetes diagnosed by doctor	0.1	0.2	1.5	-1.2	0.1	0.4	0.0	0.7	0.2	0.2	-0.8	-0.1	0.1	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.8	-0.2	-0.2	0.8	-0.1	-0.4	0.1	-0.0	0.9	-0.1	-0.2	-0.0
Arm fat mass (left)	0.1	0.4	1.3	-0.7	-0.3	1.1	-0.8	-0.5	-0.6	-0.6	-0.1	-0.6	-0.5	-0.6
Average weekly champagne plus white wine intake	0.1	0.1	0.7	0.6	-0.0	-0.6	-0.1	-0.2	-0.2	-0.2	-0.5	-0.3	-0.1	-0.8
Financial situation satisfaction	0.1	0.1	0.7	-0.5	0.3	-0.8	-0.2	0.3	-0.4	-0.3	-0.1	-0.4	-0.1	0.2
Medication: Lisinopril	0.1	0.2	1.5	-1.2	-0.0	0.2	-0.0	0.1	-0.0	-0.1	0.4	-0.1	-0.1	-0.4
Illnesses of father: High blood pressure	0.1	0.2	1.6	1.2	-0.1	-0.3	0.0	-0.4	-0.1	-0.3	-0.0	0.0	-0.1	0.2
Ever smoked	0.1	0.3	2.0	1.4	-0.0	0.4	-0.2	-0.2	-0.2	-0.2	-0.8	-0.1	0.0	0.2
Number of operations (self-reported)	0.1	0.2	0.8	0.0	0.1	0.9	-0.4	-0.2	-0.4	-0.5	-0.5	-0.5	-0.2	-0.1
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.6	0.1	-0.1	0.8	-0.0	0.0	-0.1	-0.2	0.6	-0.3	-0.1	-0.0
Cholesterol lowering medication	0.1	0.1	0.3	-0.6	0.6	0.1	0.0	0.2	0.1	-0.1	0.5	-0.1	0.2	0.1
Leg fat mass (left)	0.1	0.5	0.9	-0.7	-0.6	1.0	-0.9	-0.6	-0.7	-0.7	-0.2	-0.7	-0.7	-0.8
Blood Red Count	0.0	0.2	0.9	0.2	-0.5	0.8	-0.1	-0.1	-0.2	-0.3	-0.9	-0.3	-0.3	0.2
Neuroticism	0.0	0.1	0.5	0.7	0.3	-0.6	0.2	-0.2	-0.1	0.1	-0.4	-0.1	0.2	0.3
Hair Pigment	0.0	1.0	1.6	0.4	1.2	1.3	1.1	0.7	1.1	1.0	1.0	1.1	1.2	1.0
Tanning	0.0	0.4	2.1	-1.4	0.3	1.2	-0.2	0.4	-0.1	-0.2	-0.1	0.3	0.5	0.7
Systolic blood pressure, automated reading	0.0	0.1	0.2	0.4	-0.1	-0.0	0.2	0.2	0.2	0.2	-0.5	0.2	-0.0	0.0
Waist circumference	0.0	0.2	0.8	-0.3	-0.2	0.8	-0.2	-0.3	-0.2	-0.3	0.1	-0.1	-0.3	-0.9
Hearing difficulty/problems with background noise	0.0	0.1	0.3	-0.1	0.3	0.6	-0.1	-0.1	-0.2	-0.0	-0.4	-0.3	0.0	-0.2
Hip circumference	0.0	0.2	1.1	-1.1	0.4	0.8	-0.1	0.4	0.0	0.2	-0.3	-0.1	0.2	0.3
Medication: Cholesterol lowering	0.0	0.1	0.4	-0.0	-0.3	-0.6	0.2	0.1	0.3	0.3	-0.2	0.3	-0.0	-0.2
Number of full sisters	0.0	0.1	0.6	0.1	0.1	0.0	0.1	-0.1	0.0	0.0	0.8	0.1	0.1	-0.2

Hub : Genes

KIF3A

Models

Trait associations