[Hub]/) : Traits : Lung FVC :

chr7:149,847,287-151,474,607

Best TWAS P=2.15e-09 · Best GWAS P=2.14e-08 conditioned to 0.827

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FASTK 0.08 0.05 lasso 2 0.05 2.3e-06 -5.1 -5.2 1.7e-07 -0.54 0.06 0.93 FALSE
2 GTEx Artery Tibial FASTK 0.13 0.08 lasso 3 0.07 3.6e-06 -5.1 -5.2 2.4e-07 -0.55 0.05 0.94 FALSE
3 GTEx Brain Cerebellum ABCB8 0.25 0.25 lasso 2 0.25 4.5e-08 -5.1 5.6 2.7e-08 0.28 0.04 0.93 FALSE
4 GTEx Nerve Tibial CDK5 0.09 0.00 lasso 5 0.00 1.7e-01 5.3 -5.8 5.8e-09 -0.67 0.04 0.50 FALSE
5 GTEx Skin Sun Exposed Lower leg FASTK 0.14 0.06 lasso 6 0.04 2.4e-04 -5.1 -5.3 1.4e-07 -0.40 0.06 0.93 FALSE
6 METSIM Adipose AOC1 0.17 0.08 enet 26 0.11 3.2e-16 4.5 5.7 1.4e-08 -0.01 0.42 0.57 TRUE
7 The Cancer Genome Atlas Colon Adenocarcinoma TMUB1 0.06 0.02 enet 6 0.04 3.9e-03 5.6 -6.0 2.1e-09 -0.93 0.00 0.95 TRUE
8 The Cancer Genome Atlas Lung Adenocarcinoma ABCB8 0.07 0.04 enet 11 0.05 1.3e-06 -5.1 5.3 1.1e-07 0.17 0.00 0.98 FALSE
9 The Cancer Genome Atlas Stomach Adenocarcinoma FASTK 0.05 0.01 blup 51 0.03 3.7e-03 -4.5 -5.7 1.1e-08 -0.50 0.03 0.54 FALSE
10 The Cancer Genome Atlas Testicular Germ Cell Tumors TMEM176A 0.15 0.00 lasso 10 0.02 5.7e-02 4.9 5.2 2.0e-07 -0.01 0.01 0.29 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma ATG9B 0.05 0.04 enet 7 0.05 2.9e-05 -4.5 5.2 2.1e-07 0.30 0.01 0.92 FALSE