TWAS hub - PLXNB2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Nerve Tibial	0.2934	0.0771	6.1e-05	0.03	NA	0.073	NA	0.048	3.3e-03	NA	7.7e-06	NA	2.4e-04
2	YFS	Blood	0.0238	0.0086	5.6e-04	0.02	0.01	0.018	0.014	0.020	2.7e-07	0.00016	9.6e-07	1.3e-05	3.6e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Lung cancer (father)	5.0	5.9	8.5	-2.9	1.8
Blood Platelet Count	4.8	55.7	95.1	4.0	9.8
Length of working week for main job	3.3	3.7	4.1	-1.8	-2.0
Average weekly beer plus cider intake	3.2	4.6	5.1	-2.0	2.3
Chronic bronchitis/emphysema (mother)	3.1	3.6	5.4	2.3	-1.3
Alzheimer’s Disease (in mother)	3.0	3.5	6.0	1.0	-2.5
Medication: Metformin	3.0	4.2	8.3	-0.4	-2.9
Osteoporosis (self-reported)	3.0	3.7	3.7	-1.9	1.9
Alcohol intake frequency.	2.7	6.3	6.7	2.4	2.6
Mouth/teeth dental problems: Mouth ulcers	2.7	4.2	8.3	-0.4	2.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.7	5.6	7.3	-2.0	-2.7
Diabetes (mother)	2.6	3.3	5.3	-1.2	-2.3
Forced expiratory volume in 1-second (FEV1), predicted	2.6	5.4	6.7	-2.6	2.0
Heel T-Score	2.5	19.6	38.7	0.7	-6.2
Illnesses of mother	2.5	3.1	4.9	-1.2	2.2
Sensitivity / hurt feelings	2.3	4.0	4.3	-2.1	1.9
Eye problems/disorders: Diabetes related eye disease	2.3	2.6	4.9	0.4	-2.2
Worry too long after embarrassment	2.3	3.9	6.4	-2.5	1.1
Leg fat-free mass (right)	2.3	12.1	15.8	-4.0	2.9
Leg predicted mass (right)	2.3	12.1	16.1	-4.0	2.8
Noisy workplace	2.2	2.7	5.2	-2.3	0.4
Breast cancer (self-reported)	2.2	2.6	3.3	-1.3	1.8
Exposure to tobacco smoke outside home	2.1	2.8	5.2	-2.3	0.6
Had major operations	2.1	2.4	2.9	1.4	-1.7
Diabetes diagnosed by doctor	2.1	3.5	7.0	0.1	-2.6
Alcohol drinker status: Previous	2.1	2.4	2.5	1.6	1.5
Leg fat-free mass (left)	2.0	10.7	13.0	-3.6	2.9
Bilateral oophorectomy (both ovaries removed)	2.0	2.3	4.0	-2.0	0.8
Medication: Atenolol	2.0	2.5	5.0	0.3	-2.2
Leg predicted mass (left)	2.0	10.5	13.2	-3.6	2.8
Type 2 Diabetes (T2D) (2018)	1.8	3.4	6.8	0.2	-2.6
Other serious medical condition/disability diagnosed by doctor	1.8	2.3	4.5	0.3	2.1
Diabetes (father)	1.8	2.2	4.2	-0.4	-2.0
Average weekly fortified wine intake	1.8	2.1	2.5	-1.3	1.6
Number of incorrect matches in round	1.8	3.0	5.0	-1.0	2.2
Had other major operations	1.8	2.1	3.6	0.8	1.9
Pain all over the body in last month	1.8	1.9	3.8	1.9	0.1
Glaucoma (self-reported)	1.8	2.1	2.2	-1.5	1.5
Medication: Paracetamol	1.8	2.7	3.3	-1.8	1.5
Medication: Lisinopril	1.8	2.3	4.3	-2.1	-0.4
Cardiovascular Disease	1.7	5.6	11.2	-0.1	-3.4
Pulse wave peak to peak time	1.7	2.0	3.6	0.6	1.9
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.0	4.0	-2.0	-0.2
Fractured/broken bones in last 5 years	1.7	2.1	4.0	-0.5	2.0
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	3.4	-1.8	-0.2
Medication: Amlodipine	1.6	2.2	3.6	0.9	-1.9
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	2.9	-1.7	-0.7
Ever taken oral contraceptive pill	1.6	1.8	3.5	0.1	-1.9
Alcohol drinker status: Never	1.6	2.0	3.8	-1.9	0.4
Lupus	1.5	2.2	3.9	-0.8	-2.0
Angina	1.5	2.0	2.2	1.3	-1.5
Impedance of leg (right)	1.5	7.4	8.4	2.9	-2.5
Hip circumference	1.5	6.6	12.7	-3.6	-0.7
Prospective memory result	1.5	1.8	3.3	-0.6	1.8
Pulse wave Arterial Stiffness index	1.5	1.7	3.0	-0.7	-1.7
Medication: Gliclazide	1.5	1.6	3.0	-0.6	-1.7
Medication: Blood pressure	1.5	2.9	5.7	0.2	-2.4
Basal metabolic rate	1.5	8.2	12.2	-3.5	2.0
Number of operations (self-reported)	1.5	2.2	3.9	-0.7	2.0
Vascular/heart problems diagnosed by doctor	1.5	4.0	7.9	0.2	2.8
Alzheimer’s Disease (in father)	1.4	1.5	2.8	-1.7	0.4
HbA1C	1.4	1.6	3.1	-1.8	0.3
Chronic bronchitis/emphysema (father)	1.4	1.6	3.2	0.0	1.8
Hair/balding pattern: Pattern 2	1.4	1.8	2.6	1.6	1.0
Ever highly irritable/argumentative for 2 days	1.4	1.6	2.9	-0.6	1.7
Gout (self-reported)	1.4	1.9	3.5	-1.9	0.6
Angina (self-reported)	1.4	1.9	2.0	1.3	-1.4
Whole body fat-free mass	1.4	8.0	12.0	-3.5	2.0
Whole body water mass	1.4	8.0	12.4	-3.5	1.9
Mother’s age at death	1.4	1.7	2.2	1.5	1.1
Type 2 Diabetes (T2D) (2012)	1.3	1.4	2.7	0.5	-1.6
Chronotype (morning person)	1.3	3.1	5.3	-0.9	2.3
Heel bone mineral density (BMD) T-score, automated (left)	1.3	2.8	5.3	0.6	-2.3
Serious illness, injury or assault to yourself	1.3	1.5	1.7	-1.3	1.2
High blood pressure	1.3	3.7	7.0	-0.6	-2.6
Stomach or abdominal pain in last month	1.3	1.6	2.5	-1.6	-0.8
Diabetes (self-reported)	1.3	1.9	3.9	-0.1	-2.0
Weight	1.3	6.3	9.6	-3.1	1.8
Hypertension (Self-reported)	1.3	3.7	7.2	-0.4	-2.7
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	2.8	-1.7	-0.6
Alzheimer’s Disease (including proxy)	1.2	1.7	3.4	0.1	-1.8
Crohns Disease (2017)	1.2	2.6	3.8	1.2	1.9
Verbal and Numeric Reasoning (VNR)	1.2	2.8	3.4	-1.8	-1.5
Breast Cancer	1.2	3.0	3.7	1.9	-1.5
Rheumatoid Arthritis	1.2	1.7	2.1	1.4	1.1
Blood Red Count	1.2	11.8	19.4	4.4	-2.1
BMI	1.2	7.1	13.1	-3.6	1.0
Impedance of leg (left)	1.2	5.6	6.1	2.3	-2.5
Had menopause	1.2	1.5	2.1	1.4	0.9
Mouth/teeth dental problems	1.2	1.9	3.0	-0.9	-1.7
Happiness	1.2	1.4	2.5	1.6	0.6
Medication: Paracetamol	1.2	1.9	3.2	-1.8	0.8
Age at first live birth	1.2	2.2	3.7	-0.8	-1.9
Medication: Ibuprofen	1.2	1.4	2.6	-1.6	0.6
Commuting to job workplace: Cycle	1.2	1.5	2.6	-0.6	-1.6
Arm predicted mass (left)	1.2	6.2	9.9	-3.1	1.6
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	2.5	1.6	-0.1
Peak expiratory flow (PEF)	1.1	2.5	2.9	-1.5	-1.7
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.2	2.5	-0.1	-1.6
Medication for pain relief, constipation, heartburn	1.1	1.9	2.8	1.7	-1.0
Family relationship satisfaction	1.1	1.4	2.4	0.6	-1.6
Arm fat-free mass (left)	1.1	5.7	8.4	-2.9	1.7
Mean Putamen Volume	1.0	1.1	1.1	-1.1	1.0
Blood Eosinophil Count	1.0	7.6	11.8	3.4	1.8
Waist circumference	1.0	3.5	6.0	-2.5	1.0
Trunk fat-free mass	1.0	5.9	10.2	-3.2	1.2
Number of live births	1.0	1.4	2.6	-0.3	1.6
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	6.0	-2.4	-0.8
Mouth/teeth dental problems: Dentures	1.0	1.6	2.5	1.6	0.9
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	2.6	-1.6	-0.1
Trunk predicted mass	1.0	5.9	10.1	-3.2	1.3
Arm fat-free mass (right)	1.0	5.0	7.5	-2.7	1.6
Commuting to job workplace: Car/motor vehicle	1.0	1.1	1.5	-1.2	-0.8
Friendships satisfaction	1.0	1.2	1.7	1.3	-0.8
Heart disease (siblings)	1.0	1.2	2.0	-1.4	0.6
Intelligence (Savage-Jansen 2018)	0.9	2.7	5.2	-0.5	-2.3
Age at First Birth	0.9	1.3	2.6	0.3	-1.6
Hypothyroidism (self reported)	0.9	2.0	3.8	0.5	-2.0
Multivitamins +/- minerals	0.9	1.2	1.2	1.1	-1.1
Trunk fat mass	0.9	4.0	6.2	-2.5	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	3.2	1.0	-1.8
Medication: Simvastatin	0.9	1.3	1.4	1.2	-1.1
Fluid intelligence score	0.9	1.8	2.4	-1.1	-1.5
Arm fat mass (right)	0.9	3.7	6.0	-2.4	1.2
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	2.1	1.2	-1.5
Comparative body size at age 10	0.9	2.4	2.7	-1.6	1.5
Arm predicted mass (right)	0.9	4.8	6.8	-2.6	1.7
Age at last live birth	0.9	1.4	2.0	-1.4	-0.9
Handedness (chirality/laterality): Left-handed	0.9	1.1	1.2	-1.0	1.1
Mood swings	0.9	1.6	3.1	-1.8	-0.5
Arm fat mass (left)	0.9	3.8	5.4	-2.3	1.5
Tinnitus: Yes, now most or all of the time	0.9	1.0	1.3	-0.9	-1.1
Eye problems/disorders: Glaucoma	0.9	1.0	1.2	-0.9	1.1
Medication: Atorvastatin	0.9	1.1	1.8	-0.5	-1.4
Illnesses of father: High blood pressure	0.9	1.1	1.9	-0.5	-1.4
Ever smoked	0.9	1.6	3.1	-0.0	1.8
Ovarian Cancer	0.8	1.0	1.4	1.2	0.8
Triglycerides	0.8	1.3	1.5	1.2	1.0
Smoking Status	0.8	2.0	3.8	-0.5	1.9
Neuroticism	0.8	1.8	3.6	-1.9	0.3
Townsend deprivation index at recruitment	0.8	1.1	2.0	0.4	1.4
Supplements: Glucosamine	0.8	1.0	1.3	1.1	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	2.4	-1.6	0.3
Arm fat percentage (right)	0.8	3.2	5.0	-2.2	1.2
Health satisfaction	0.8	1.0	1.1	0.9	-1.1
Number of full sisters	0.8	1.0	1.8	0.4	-1.4
Suffer from ‘nerves’	0.8	1.3	1.8	-1.4	-0.9
Commuting to job workplace: Walk	0.8	0.8	1.2	0.7	1.1
Risk taking	0.8	1.1	1.4	-0.9	-1.2
Neuroticism (Nagel 2018)	0.7	1.5	2.5	-1.6	0.7
Waist Hip Ratio (WHR)	0.7	3.0	5.7	-0.6	2.4
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	1.6	1.3	0.0
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	0.9	-0.9	-0.9
Neuroticism score	0.7	1.5	2.7	-1.6	0.5
Depression (self-reported)	0.7	0.8	1.4	1.2	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	3.9	-2.0	-0.8
Breastfed as a baby	0.7	0.9	1.2	-1.1	0.8
Whole body fat mass	0.7	3.0	5.1	-2.3	0.9
Comparative height size at age 10	0.7	3.9	6.2	-1.2	2.5
Arm fat percentage (left)	0.7	2.6	3.9	-2.0	1.2
Average weekly red wine intake	0.7	1.0	1.1	-1.1	-1.0
Medication for cholesterol	0.7	1.0	1.9	-0.4	1.4
Medication: Bendroflumethiazide	0.7	1.1	2.1	1.4	0.3
Ever had prostate specific antigen (PSA) test	0.7	0.8	1.1	-1.1	0.7
Schizophrenia (2018)	0.6	1.3	1.6	1.0	-1.3
Blood White Count	0.6	4.5	6.7	1.5	2.6
Lung FVC	0.6	2.9	5.5	-0.5	-2.3
Hand grip strength (left)	0.6	1.6	3.2	0.2	-1.8
Systolic blood pressure, automated reading	0.6	1.8	2.4	-1.1	-1.6
Current tobacco smoking	0.6	0.9	1.8	0.0	1.4
Age when periods started (menarche)	0.6	1.5	2.3	1.5	0.9
Forced vital capacity (FVC)	0.6	2.4	4.8	-2.2	-0.2
Time employed in main current job	0.6	0.7	1.2	-1.1	0.4
Standing height	0.6	5.5	6.7	-2.6	2.1
High blood pressure (siblings)	0.6	0.9	1.8	-0.2	-1.3
Shortness of breath walking on level ground	0.6	0.7	1.5	0.1	1.2
Emphysema/chronic bronchitis	0.6	0.7	1.3	0.3	1.1
Medication: Allopurinol	0.6	0.8	1.5	-1.2	0.2
Illnesses of siblings: Diabetes	0.6	0.8	1.6	-1.2	-0.1
Qualifications: nursing, teaching	0.6	0.9	1.4	0.7	-1.2
Mineral and other dietary supplements	0.6	0.8	1.3	-1.1	-0.5
Wears glasses or contact lenses	0.6	0.7	1.5	1.2	0.1
Pain type(s) experienced in last month: Hip pain	0.6	0.7	1.5	1.2	-0.1
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.7	1.3	-0.1
Diastolic blood pressure, automated reading	0.6	1.8	3.6	-1.9	-0.0
Leg fat mass (left)	0.6	2.4	4.3	-2.1	0.6
Irritable Bowel Disease (IBD)	0.5	1.2	1.8	0.7	1.3
Crohns Disease (2012)	0.5	0.9	1.2	0.7	1.1
LDL Cholesterol	0.5	0.8	1.6	1.3	-0.2
Ulcerative Colitis	0.5	0.8	1.6	1.3	0.0
Systolic Blood Pressure	0.5	2.6	5.0	-0.5	-2.2
Respiratory disease	0.5	1.0	1.0	1.0	1.0
Relative age of first facial hair	0.5	1.1	2.1	0.1	1.4
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.3	1.1	0.0
Supplements: Zinc	0.5	0.6	0.7	-0.8	-0.7
Medication: Co-codamol	0.5	0.5	0.7	0.6	0.8
Trunk fat percentage	0.5	2.0	3.1	-1.8	0.9
Hand grip strength (right)	0.5	1.3	2.3	-1.5	-0.6
Body mass index (BMI)	0.5	2.3	4.0	-2.0	0.8
Qualifications: None of the above	0.5	1.0	1.3	0.9	1.2
Father’s age at death	0.5	0.7	1.4	1.2	0.1
Worrier / anxious feelings	0.5	0.9	1.3	-0.7	1.2
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	0.9	-0.8	-1.0
Tense / ‘highly strung’	0.5	0.8	1.6	-0.3	-1.3
Hair/balding pattern: Pattern 4	0.5	1.1	2.0	-0.5	-1.4
Birth weight of first child	0.5	0.9	1.6	0.4	1.3
Body fat percentage	0.5	2.0	3.5	-1.9	0.6
Medication: Blood pressure	0.5	0.8	1.1	-0.7	-1.0
Leg fat mass (right)	0.5	1.8	3.3	-1.8	0.5
Knee pain experienced in last month	0.5	0.8	1.1	-0.8	1.0
Illnesses of father: Heart disease	0.5	0.7	1.1	0.5	-1.0
Loneliness, isolation	0.5	0.6	1.2	1.1	0.3
Long-standing illness, disability or infirmity	0.5	0.8	1.1	1.0	0.7
Osteoarthritis (self-reported)	0.5	0.7	1.3	0.2	1.2
Average weekly champagne plus white wine intake	0.5	0.6	1.3	-0.1	-1.1
Miserableness	0.5	0.9	1.7	-1.3	-0.3
Cholesterol lowering medication	0.5	0.7	0.8	0.8	-0.9
Bipolar Disorder or Schizophrenia	0.4	0.9	1.1	1.0	-0.8
Worry (Nagel 2018)	0.4	0.8	1.6	-1.3	-0.2
Schizophrenia (2014)	0.4	0.8	0.9	0.9	-1.0
Average weekly spirits intake	0.4	0.5	0.6	-0.8	0.6
Hearing difficulty/problems: Yes	0.4	0.6	1.0	-0.6	1.0
Vitamin and mineral supplements	0.4	0.5	0.7	-0.8	0.7
Maternal smoking around birth	0.4	0.5	1.0	1.0	0.1
Qualifications: CSEs or equivalent	0.4	0.5	1.0	-1.0	0.1
Hearing difficulty/problems with background noise	0.4	0.7	1.3	0.2	-1.2
Medication: Ramipril	0.4	0.6	0.9	-0.4	-1.0
Medication: Cholesterol lowering	0.4	0.7	1.3	-0.2	-1.1
Loud music exposure frequency	0.4	0.5	0.7	0.6	-0.8
Forced vital capacity (FVC), Best measure	0.4	1.3	2.6	-1.6	-0.2
Migraine (self-reported)	0.4	0.5	0.6	-0.7	0.8
Medication: Omeprazole	0.4	0.5	0.8	-0.9	-0.4
Chest pain or discomfort	0.4	0.6	1.0	1.0	-0.4
Smoking status: Previous	0.4	0.6	1.1	0.5	1.0
Financial situation satisfaction	0.4	0.5	0.9	-0.2	0.9
Schizophrenia vs Biploar Disorder	0.3	0.3	0.4	0.6	-0.6
Reaction Time	0.3	0.6	1.1	-0.4	1.0
Neuroticism (2016)	0.3	0.4	0.5	0.5	0.7
Primary Biliary Cirrhosis	0.3	0.5	0.9	0.1	0.9
Height	0.3	5.2	8.5	-1.4	2.9
Number of treatments/medications taken	0.3	0.5	0.8	0.4	0.9
Medication for hormone replacement therapy	0.3	0.3	0.7	0.8	-0.1
Medication: Levothyroxine sodium	0.3	0.5	0.9	1.0	0.2
Sitting height	0.3	2.3	4.7	-2.2	-0.1
Nervous feelings	0.3	0.5	0.8	-0.9	0.5
Allergy	0.3	0.7	1.1	-0.5	-1.0
Hair/balding pattern: Pattern 3	0.3	0.5	0.5	0.7	0.6
Qualifications: A levels/AS levels or equivalent	0.3	0.6	0.8	-0.9	-0.7
Pulse wave reflection index	0.3	0.4	0.5	-0.5	-0.7
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.8	0.2	0.9
Blood clot in the leg (DVT)	0.3	0.4	0.6	0.5	0.8
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	0.8	-0.3	0.9
Medication: Ventolin 100micrograms inhaler	0.3	0.3	0.5	0.4	0.7
Wheeze or whistling in the chest in last year	0.3	0.6	0.6	-0.8	0.8
Number of children fathered	0.3	0.3	0.4	-0.6	-0.4
Medication: Seretide 50 evohaler	0.3	0.4	0.4	-0.6	0.6
Heart disease (mother)	0.3	0.4	0.6	0.8	-0.4
Overall health rating	0.3	0.6	1.0	1.0	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.7	0.0	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	0.7	-0.8	0.3
Illnesses of father: None of the above (group 1)	0.3	0.4	0.5	-0.5	0.7
Smoking status: Current	0.3	0.5	0.8	-0.4	0.9
Hearing aid user	0.3	0.4	0.8	0.9	-0.1
High cholesterol (Self-reported)	0.3	0.5	0.7	-0.8	-0.6
Leg fat percentage (left)	0.3	1.1	1.7	-1.3	-0.7
Ever depressed for a whole week	0.3	0.4	0.4	0.6	-0.6
Myopia	0.3	0.5	0.8	-0.3	-0.9
Basal cell carcinoma (self-reported)	0.3	0.4	0.6	0.3	0.8
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	0.4	0.7	0.5
Impedance of whole body	0.3	1.6	2.8	1.7	-0.7
Depressed Affect (Nagel 2018)	0.2	0.3	0.5	-0.7	0.4
Depression (Nagel 2018)	0.2	0.3	0.6	0.3	0.8
Prostate Cancer	0.2	0.3	0.5	0.7	0.2
Lung FEV1/FVC ratio	0.2	1.3	1.3	-1.1	-1.1
Tanning	0.2	2.5	4.5	-2.1	0.7
Ever had hysterectomy (womb removed)	0.2	0.2	0.3	0.3	0.6
Fed-up feelings	0.2	0.3	0.4	-0.7	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.6	-0.2	0.8
Relative age voice broke	0.2	0.3	0.6	0.8	-0.0
Taking other prescription medications	0.2	0.2	0.5	0.2	0.7
Past tobacco smoking	0.2	0.4	0.8	-0.2	-0.9
Illnesses of siblings	0.2	0.3	0.4	0.3	0.7
Impedance of arm (left)	0.2	0.8	1.5	1.2	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	0.4	-0.3	0.6
Headache pain in last month	0.2	0.3	0.7	-0.8	0.0
Leg fat percentage (right)	0.2	0.6	0.6	-0.8	-0.7
Qualifications: College or University degree	0.2	0.7	1.2	0.3	-1.1
Eye problems/disorders: None of the above	0.2	0.2	0.4	0.6	-0.2
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.3	-0.3	-0.5
Leg pain on walking	0.2	0.3	0.4	-0.6	-0.5
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.5	-0.7	0.1
Back pain experienced in last month	0.2	0.3	0.4	-0.5	0.7
Asthma (self-reported)	0.2	0.3	0.4	0.6	0.6
Number of self-reported non-cancer illnesses	0.2	0.3	0.5	0.2	-0.7
Pain experienced in last month	0.2	0.4	0.7	-0.4	-0.8
Supplements: Calcium	0.2	0.2	0.5	-0.7	-0.0
Bipolar Disorder (2018)	0.1	0.2	0.2	0.5	0.3
Ulcerative Colitis (UC)	0.1	0.3	0.3	0.5	0.5
HDL Cholesterol	0.1	0.1	0.2	-0.4	0.2
Hair Pigment	0.1	2.7	4.7	-2.2	-0.9
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.2	-0.2	0.4
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.1	-0.3	-0.4
Alcohol usually taken with meals	0.1	0.1	0.2	0.4	-0.2
Heart attack	0.1	0.1	0.2	-0.1	-0.5
Falls in the last year	0.1	0.1	0.2	0.1	0.4
Pulse rate	0.1	0.2	0.3	0.2	-0.5
Exposure to tobacco smoke at home	0.1	0.1	0.1	0.3	0.3
Birth weight	0.1	0.1	0.2	-0.5	0.1
Number of full brothers	0.1	0.2	0.2	-0.4	-0.4
Neck or shoulder pain in last month	0.1	0.1	0.2	0.4	0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.3	0.5	0.1
Pulse rate, automated reading	0.1	0.3	0.4	0.4	-0.6
Supplements: Vitamin C	0.1	0.1	0.3	-0.2	-0.5
Eye problems/disorders: Cataract	0.1	0.2	0.3	0.6	-0.0
Medication: Aspirin	0.1	0.2	0.2	0.3	-0.5
Guilty feelings	0.1	0.1	0.2	0.1	-0.4
Commuting to job workplace: Public transport	0.1	0.2	0.3	0.2	0.5
Age started oral contraceptive pill	0.1	0.2	0.3	-0.2	-0.5
Unable to work because of sickness or disability	0.1	0.1	0.2	-0.3	0.4
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.4	-0.1	-0.6
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.1	-0.3	-0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
Fasting Glucose	0.0	0.0	0.0	0.2	0.0
Allergy or Eczema	0.0	0.1	0.1	0.2	-0.3
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.0	-0.2	0.0
Severe depression (siblings)	0.0	0.0	0.0	0.1	-0.2
Pack years adult smoking proportion	0.0	0.1	0.1	-0.3	0.0
High blood pressure (mother)	0.0	0.0	0.0	-0.1	-0.2
Financial difficulties in last 2 years	0.0	0.0	0.0	-0.1	0.2
Impedance of arm (right)	0.0	0.1	0.3	0.5	-0.0
Alcohol intake versus 10 years previously	0.0	0.0	0.1	-0.0	-0.3
Asthma	0.0	0.1	0.1	0.2	0.4
Medication: Lansoprazole	0.0	0.0	0.0	-0.1	0.2
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.0	-0.1	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.0	0.1	-0.3	0.0
Mean time to correctly identify matches	0.0	0.0	0.0	-0.2	0.2
Medication: Aspirin	0.0	0.0	0.0	0.1	-0.2
Ever had bowel cancer screening	0.0	0.0	0.0	-0.2	0.1
Irritability	0.0	0.0	0.0	-0.1	0.1
Pack years of smoking	0.0	0.0	0.1	-0.3	-0.1

Hub : Genes

PLXNB2

Models

Trait associations