TWAS hub - GMIP

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Nerve Tibial	0.1856	0.0671	8.2e-04	0.089	NA	0.028	NA	0.029	6.8e-07	NA	4.0e-03	NA	3.9e-03
2	GTEx	Testis	0.1480	0.0690	8.4e-03	0.018	NA	-0.001	NA	-0.004	5.3e-02	NA	3.6e-01	NA	5.4e-01
3	METSIM	Adipose	0.0652	0.0266	1.0e-03	0.031	0.015	0.016	0.018	0.026	1.7e-05	1.9e-03	1.6e-03	7.8e-04	7.8e-05
4	YFS	Blood	0.1009	0.0224	0.0e+00	0.062	0.073	0.076	0.075	0.071	1.9e-19	8.2e-23	9.6e-24	2.1e-23	3.7e-22
5	TCGA	Breast Invasive Carcinoma	0.0234	0.0125	2.2e-04	0.009	0.015	0.015	NA	0.015	5.4e-03	3.6e-04	3.0e-04	NA	4.4e-04
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0277	0.0194	8.0e-03	0.018	0.014	0.014	NA	0.018	3.8e-03	9.4e-03	9.3e-03	NA	3.2e-03
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0650	0.0340	3.1e-03	0.019	0.032	0.042	NA	0.040	2.9e-02	5.9e-03	1.9e-03	NA	2.3e-03
8	TCGA	Brain Lower Grade Glioma	0.0691	0.0368	2.6e-05	0.043	0.044	0.035	NA	0.031	1.0e-05	8.5e-06	6.2e-05	NA	1.6e-04
9	TCGA	Ovarian Serous Cystadenocarcinoma	0.0730	0.0390	1.3e-03	0.004	0.017	0.013	NA	0.005	1.7e-01	2.3e-02	4.4e-02	NA	1.4e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder or Schizophrenia	8.2	20.1	35.0	-4.8	3.3	-4.6	3.9	4.1	5.9	4.8	4.8	3.6
Schizophrenia (2014)	8.2	18.0	34.0	-4.2	2.8	-3.7	2.6	3.6	5.8	4.9	5.3	4.1
Triglycerides	6.6	10.8	32.0	-4.2	0.1	-5.1	-1.9	1.8	-2.5	2.9	0.4	-5.7
Schizophrenia (2018)	6.4	13.3	22.8	-3.1	3.5	-2.5	2.3	3.5	4.8	4.2	4.0	4.2
LDL Cholesterol	5.9	9.4	26.5	-4.0	-0.3	-5.2	-1.1	2.6	-0.8	3.5	1.3	-4.4
Breast cancer (self-reported)	5.8	6.9	12.0	-2.4	0.8	-3.0	1.7	2.3	3.5	3.4	3.2	2.2
High cholesterol (Self-reported)	5.8	10.2	36.2	-2.4	-2.3	-2.5	-4.7	-0.5	-4.0	0.1	0.1	-6.0
Bipolar Disorder (2018)	5.2	8.2	17.4	-3.8	0.9	-4.2	3.1	2.4	3.5	2.5	2.6	0.6
Medication: Cholesterol lowering	5.2	8.0	26.0	-1.8	-0.3	-2.0	-4.3	-0.1	-4.4	0.3	-0.8	-5.1
Blood Platelet Count	4.2	49.0	130.0	-2.9	1.6	-1.4	10.2	4.0	11.4	5.5	5.4	10.9
Medication: Atorvastatin	4.2	5.2	15.9	-1.3	-0.9	-1.6	-3.0	-1.7	-3.5	-0.4	-1.2	-4.0
Breast Cancer	3.8	9.2	27.1	1.2	-2.8	0.1	-3.4	-3.1	-3.9	-2.1	-2.3	-5.2
Prostate Cancer	3.7	5.2	11.1	-2.5	1.3	-1.7	2.0	1.8	3.3	2.3	2.6	2.5
Mouth/teeth dental problems: Mouth ulcers	3.4	5.4	10.4	-2.7	0.6	-1.7	0.8	2.5	2.6	2.9	3.2	2.5
Myopia	3.4	5.0	11.9	-1.6	0.5	-2.1	3.4	1.5	3.5	1.0	2.2	2.5
Blood Eosinophil Count	3.3	25.7	54.2	-5.5	2.7	-3.9	4.2	3.3	7.4	5.2	6.6	5.0
Hearing difficulty/problems: Yes	3.1	4.7	11.1	2.0	-0.7	2.0	-1.9	-1.6	-3.3	-1.8	-3.0	-1.9
Medication: Simvastatin	3.1	4.5	17.1	-0.9	-1.2	-1.1	-3.1	-0.7	-3.0	-1.0	-0.4	-4.1
Commuting to job workplace: Walk	3.0	3.2	8.5	0.1	-1.8	-0.3	-2.9	-1.8	-2.1	-1.5	-0.1	-2.8
Ovarian Cancer	2.8	3.6	9.7	0.5	-1.3	1.1	-2.2	-1.8	-2.8	-1.4	-1.5	-3.1
Angina	2.8	3.6	13.1	0.7	-1.1	2.0	-2.1	-0.4	-3.6	-1.2	-2.5	-1.4
Sensitivity / hurt feelings	2.7	4.6	11.0	-1.6	0.1	-0.6	3.2	0.5	3.3	2.2	2.0	2.8
Had menopause	2.7	3.4	8.9	2.8	-1.8	3.0	-0.4	-0.6	-0.8	-2.4	-1.7	0.5
Falls in the last year	2.7	3.7	6.6	-2.6	1.4	-1.7	0.1	2.2	1.3	2.3	2.4	1.9
Long-standing illness, disability or infirmity	2.7	4.1	14.3	1.4	-0.9	2.2	-2.0	-0.9	-3.8	-1.5	-2.8	-0.0
Pack years adult smoking proportion	2.6	3.9	8.5	-1.2	1.0	-0.7	2.1	2.0	2.2	2.6	1.8	2.9
Impedance of arm (right)	2.6	12.3	30.9	-2.9	2.1	-4.5	5.4	2.2	5.6	2.0	2.8	-0.7
Angina (self-reported)	2.6	3.4	12.3	0.4	-1.2	1.9	-2.2	-0.4	-3.5	-0.9	-2.2	-1.5
Medication: Lisinopril	2.6	3.3	7.0	1.4	-0.3	1.4	-1.4	-2.6	-2.0	-2.3	-1.8	-2.2
Pack years of smoking	2.6	3.8	7.0	-1.4	0.7	-1.0	2.2	1.9	2.2	2.6	1.9	2.6
Coronary Artery Disease (CAD)	2.5	3.0	15.7	-0.4	-0.7	-1.6	-1.3	-2.1	-1.3	0.0	-0.4	-4.0
Medication: Amlodipine	2.5	3.6	7.4	0.6	-2.7	1.5	-1.6	-1.9	-2.0	-2.7	-1.7	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.4	2.9	5.6	1.4	-1.1	2.4	-1.6	-1.4	-1.9	-2.0	-2.1	-0.1
Impedance of leg (right)	2.3	11.2	34.6	0.1	0.7	0.3	5.4	2.1	5.9	2.1	2.3	4.7
Impedance of arm (left)	2.3	10.7	28.7	-2.5	1.8	-4.5	4.7	2.0	5.4	1.6	2.8	-0.9
Mouth/teeth dental problems: Bleeding gums	2.3	3.0	8.9	1.7	-1.4	1.9	-2.0	-0.9	-3.0	-0.5	-1.7	-1.4
Number of children fathered	2.3	2.6	6.1	-1.4	1.6	-1.5	-0.1	2.5	0.8	2.4	1.8	1.2
Age at first live birth	2.3	4.0	16.6	0.8	-1.3	-0.6	0.7	-2.9	-1.0	-2.0	-1.7	-4.1
Supplements: Calcium	2.3	2.6	6.2	-0.8	0.6	-0.3	0.9	1.7	2.5	1.9	2.4	1.7
Impedance of whole body	2.3	11.7	40.6	-2.0	1.5	-2.5	5.5	2.0	6.4	2.2	3.0	2.0
Primary Biliary Cirrhosis	2.2	3.2	9.3	0.2	-1.9	-0.5	-3.0	-1.8	-2.1	-2.3	0.0	-1.4
Severe depression (siblings)	2.2	2.5	5.9	-1.5	2.4	-1.3	0.8	2.2	0.8	1.7	1.1	1.3
Diabetes (self-reported)	2.2	3.4	8.5	1.8	-1.6	2.3	0.3	-2.3	-1.4	-2.9	-1.6	0.9
Medication: Ibuprofen (e.g. Nurofen)	2.2	2.7	7.7	0.2	1.1	0.9	1.5	2.8	1.0	2.5	0.7	2.2
Had major operations	2.2	2.6	6.5	1.5	0.9	0.8	-1.6	-0.8	-2.6	-1.6	-2.2	-1.6
Age at last live birth	2.2	3.2	7.8	1.2	-0.2	1.0	0.3	-2.0	-2.0	-2.2	-2.8	-2.4
Irritable Bowel Disease (IBD)	2.1	4.9	7.5	-2.2	2.1	-1.7	1.2	2.1	2.5	2.3	2.7	2.7
Chest pain or discomfort	2.1	3.0	6.0	1.8	-0.6	2.5	-1.5	-2.1	-2.1	-1.6	-2.0	-0.0
Diabetes diagnosed by doctor	2.1	3.4	7.8	1.4	-1.6	2.5	-0.7	-1.8	-1.9	-2.8	-1.6	1.5
Crohns Disease (2017)	2.0	4.4	11.4	-1.0	2.8	-0.6	1.8	2.2	2.3	1.8	1.7	3.4
Rheumatoid Arthritis	2.0	2.8	9.0	-1.0	1.9	-0.6	2.5	0.8	3.0	1.0	1.0	1.6
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	5.3	1.0	-0.1	2.3	-0.7	-1.6	-2.0	-1.5	-1.6	1.3
Impedance of leg (left)	2.0	9.6	30.7	-0.5	0.2	-0.1	4.5	1.6	5.5	2.0	2.6	4.6
Leg fat percentage (right)	2.0	7.1	25.0	-0.7	1.5	0.8	-2.3	5.0	-0.6	3.4	1.7	3.9
Heart disease (siblings)	2.0	2.4	6.0	-1.3	-1.7	-1.7	-2.5	-0.7	-1.1	-0.5	1.1	-2.3
Average weekly spirits intake	1.9	2.3	7.3	-1.2	0.3	-0.3	-1.0	2.3	0.1	2.7	1.3	2.0
Supplements: Zinc	1.9	2.0	5.6	-0.7	0.5	-1.7	0.7	1.4	1.6	2.4	1.8	0.8
Exposure to tobacco smoke at home	1.9	2.1	6.6	-1.9	-0.8	-1.3	-0.4	0.5	1.5	1.4	2.6	1.4
Bilateral oophorectomy (both ovaries removed)	1.8	2.1	8.8	-0.5	2.0	-0.5	-0.9	3.0	-0.1	1.0	0.7	1.9
Time employed in main current job	1.8	2.0	9.5	-0.0	1.5	0.6	1.0	2.1	0.7	0.6	-0.1	3.1
Headache pain in last month	1.8	3.2	8.7	-0.6	1.2	0.2	1.8	1.7	2.1	3.0	1.4	2.4
Comparative body size at age 10	1.8	4.9	13.5	2.1	-1.2	-0.0	-2.8	-1.6	-3.7	-1.9	-1.9	-2.7
Migraine (self-reported)	1.8	2.2	6.6	0.5	2.6	1.6	0.7	2.0	-0.2	1.7	-0.2	1.7
Suffer from ‘nerves’	1.8	2.8	8.5	-2.1	-0.8	-2.9	0.4	1.6	1.0	1.4	2.3	0.8
Eye problems/disorders: Glaucoma	1.8	2.2	5.1	2.2	-0.9	2.2	0.2	-1.0	-0.9	-1.4	-2.0	-1.0
Leg fat percentage (left)	1.8	6.6	20.1	-0.9	1.1	0.7	-3.0	4.5	-1.0	3.2	1.7	3.8
Worry (Nagel 2018)	1.7	3.6	10.5	-3.0	-0.3	-3.2	0.1	0.7	1.6	1.4	2.8	0.6
Waist Hip Ratio (WHR)	1.7	7.8	21.1	3.7	-0.8	4.6	-0.6	-2.4	-2.5	-3.2	-3.4	0.7
Chronotype (morning person)	1.7	4.0	8.3	2.0	-1.4	1.5	0.2	-2.7	-1.6	-2.7	-2.9	-1.7
Trunk fat percentage	1.7	6.8	23.8	-2.7	1.7	-2.5	-1.3	4.9	0.6	3.2	2.8	0.8
Medication: Gliclazide	1.7	2.0	6.4	1.6	-0.4	2.5	1.0	-0.7	-0.1	-1.3	-1.6	1.6
Mother’s age at death	1.7	2.2	5.4	2.3	-0.8	1.2	0.0	-0.8	-1.9	-1.1	-1.9	-1.7
Townsend deprivation index at recruitment	1.6	2.3	4.9	2.2	0.4	1.0	-1.8	-1.4	-2.2	-0.7	-1.4	-1.6
Medication: Lansoprazole	1.6	1.8	5.6	1.8	-1.0	2.4	-0.3	-0.6	-0.9	-1.2	-1.5	1.3
Medication for cholesterol, blood pressure or diabetes	1.6	2.7	10.2	-0.0	0.1	-0.5	2.4	0.3	3.2	0.9	1.7	2.1
Body fat percentage	1.6	6.3	24.3	-2.0	1.6	-1.4	-2.1	4.9	-0.1	3.2	2.4	1.9
Alcohol intake frequency.	1.6	3.7	7.5	-1.7	2.3	-1.2	0.8	2.7	1.4	2.0	1.7	2.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	4.8	-1.8	0.8	-0.7	0.4	1.1	2.2	1.7	1.7	0.8
Smoking status: Current	1.6	2.5	7.3	-0.1	1.5	0.5	0.1	2.5	1.2	1.6	1.4	2.7
Neuroticism (Nagel 2018)	1.5	3.6	8.9	-2.7	-0.6	-2.0	-0.0	1.2	1.8	2.1	3.0	1.8
Alzheimer’s Disease (in mother)	1.5	1.7	3.5	0.7	1.7	1.4	1.6	1.7	0.8	0.3	-0.7	1.9
Current tobacco smoking	1.5	2.4	7.2	-0.1	1.7	0.6	0.1	2.6	0.9	1.4	1.1	2.7
Alcohol intake versus 10 years previously	1.5	2.2	7.8	-1.1	-1.0	0.2	-0.2	2.0	0.7	1.9	1.4	2.8
Pulse rate	1.5	2.4	7.8	0.8	1.0	1.9	2.5	0.9	1.0	0.2	-0.9	2.8
Medication: Ibuprofen	1.5	1.8	4.1	0.8	0.5	1.6	1.2	1.9	0.7	1.8	0.3	2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	4.8	2.2	-1.4	1.6	-0.6	-0.2	-1.6	-1.0	-1.7	-0.5
Medication: Aspirin	1.5	2.0	4.8	0.2	-0.8	1.3	-2.0	-1.5	-2.2	-0.8	-1.1	-1.5
Irritability	1.5	2.6	7.2	-2.7	-0.4	-1.9	0.2	-0.1	0.9	1.6	1.6	-2.5
Schizophrenia vs Biploar Disorder	1.4	1.9	5.3	-0.4	2.3	0.4	0.2	1.1	1.3	1.8	1.2	2.0
Ulcerative Colitis (UC)	1.4	2.6	5.9	-2.4	0.5	-1.9	0.3	1.1	1.6	1.7	2.4	0.9
Blood Red Count	1.4	13.1	35.9	6.0	-2.2	5.9	-1.1	-3.0	-2.4	-3.8	-3.3	0.8
Neuroticism	1.4	3.4	9.1	-3.0	-1.1	-2.5	0.3	0.9	1.4	2.1	2.5	0.9
Maternal smoking around birth	1.4	2.0	10.3	-0.4	0.9	1.2	-0.5	1.8	0.8	0.6	0.4	3.2
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.7	8.4	-0.2	1.1	-0.4	-0.8	-1.3	-1.2	-0.6	-1.1	-2.9
Qualifications: College or University degree	1.4	4.4	14.5	1.8	0.2	-0.1	1.2	-2.9	-1.2	-1.8	-2.8	-3.8
Commuting to job workplace: Car/motor vehicle	1.4	1.6	4.3	-0.3	2.0	-0.9	0.1	1.8	0.5	1.3	0.5	2.1
Illnesses of father: Heart disease	1.4	2.0	7.7	-0.3	1.2	-1.5	-0.3	-1.1	-1.6	-1.0	-1.2	-2.8
Arm fat percentage (left)	1.4	5.5	18.7	-1.9	1.6	-1.7	-3.1	4.3	-1.4	2.5	1.8	0.6
Loneliness, isolation	1.4	1.9	6.1	-0.9	1.2	-0.0	-1.5	2.5	-0.3	1.6	0.9	1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	3.1	5.6	1.4	1.0	1.2	-2.3	-1.8	-2.4	-2.1	-2.0	-0.8
Vascular/heart problems diagnosed by doctor	1.4	3.8	7.1	-1.4	1.0	-2.7	1.8	2.1	2.5	2.5	1.9	-0.1
Ever had hysterectomy (womb removed)	1.3	1.4	5.1	0.6	2.2	0.6	1.0	2.2	-0.0	0.9	-0.3	0.4
Diabetes (mother)	1.3	1.6	9.2	0.4	-0.5	1.5	0.8	0.2	1.3	-0.5	0.5	3.0
Medication: Levothyroxine sodium	1.3	2.2	3.6	-1.6	1.5	-0.9	0.4	1.5	1.9	1.1	1.9	1.9
Sitting height	1.3	9.1	19.7	-4.0	-0.2	-3.9	4.1	-0.5	4.4	1.4	2.6	-2.3
Trunk fat mass	1.3	5.4	16.4	-2.7	1.4	-2.6	-1.7	4.1	0.1	2.8	2.3	-0.1
Arm fat percentage (right)	1.3	5.2	19.2	-1.9	1.6	-1.6	-2.6	4.4	-1.2	2.6	1.6	0.9
Glaucoma (self-reported)	1.3	1.6	4.7	2.2	-0.5	1.8	0.2	-0.5	-0.9	-1.4	-1.8	-0.4
Neck or shoulder pain in last month	1.3	1.8	7.6	-0.1	0.6	0.5	0.5	1.7	1.4	1.3	1.1	2.8
Back pain experienced in last month	1.3	1.8	4.6	-0.8	-1.7	0.3	-2.1	2.0	-1.4	1.1	0.7	0.7
Average weekly champagne plus white wine intake	1.3	1.8	4.1	1.0	-1.0	0.7	-0.6	-1.2	-1.7	-2.0	-1.7	-1.4
Guilty feelings	1.3	1.9	5.2	1.4	-0.8	2.0	-1.3	0.2	-2.3	-0.8	-1.6	0.6
Vitamin and mineral supplements	1.2	1.6	4.5	-0.2	-1.4	-0.6	-1.5	-0.5	-1.8	-1.1	-0.9	-2.1
High blood pressure	1.2	3.3	6.6	1.3	-0.9	2.6	-1.2	-2.5	-2.0	-2.5	-1.7	-0.0
Nervous feelings	1.2	2.3	6.4	-2.5	-1.9	-2.3	0.2	-0.2	0.6	0.9	1.9	-0.4
Hair/balding pattern: Pattern 2	1.2	1.5	7.2	-0.3	-0.2	0.4	0.1	1.8	0.4	1.2	1.0	2.7
Qualifications: None of the above	1.2	2.7	11.0	-0.9	0.2	0.8	-0.2	1.6	1.3	1.9	1.9	3.3
Standing height	1.2	11.9	30.8	-3.4	-0.7	-4.8	4.5	-1.9	3.9	-0.3	1.5	-5.5
Medication: Paracetamol	1.2	2.0	7.4	-0.6	0.2	0.5	-1.2	1.0	0.5	2.1	1.8	2.7
Overall health rating	1.2	2.5	6.9	-1.4	-0.1	-0.5	-1.4	2.6	-0.7	1.9	1.4	2.2
Hypertension (Self-reported)	1.2	3.3	9.0	1.6	-0.8	3.0	-0.7	-2.0	-1.9	-2.3	-1.9	0.7
Handedness (chirality/laterality): Left-handed	1.2	1.5	3.9	1.1	-1.5	0.5	1.6	-0.6	-0.3	-2.0	-1.6	-0.5
Qualifications: nursing, teaching	1.2	1.9	5.7	1.1	0.4	0.3	-0.2	-1.1	-1.7	-1.2	-2.4	-2.1
Medication: Blood pressure	1.2	2.4	5.4	1.7	-0.6	2.3	0.3	-2.1	-0.5	-2.3	-1.3	1.1
Supplements: Fish oil (including cod liver oil)	1.2	1.6	5.2	0.4	-1.4	0.6	-0.4	-2.3	-0.2	-1.7	-0.1	-1.9
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	4.4	0.9	0.2	1.7	-1.0	0.0	-2.1	-0.5	-1.8	0.3
Alzheimer’s Disease (including proxy)	1.1	1.6	5.7	0.4	1.3	1.5	0.1	2.4	-0.2	0.7	-0.4	1.9
Age at First Birth	1.1	1.6	5.3	0.9	-1.9	0.6	2.3	-0.4	-0.2	-1.0	-1.5	-0.9
Chronic bronchitis/emphysema (father)	1.1	1.3	2.8	1.3	-0.8	1.1	-0.4	-0.1	-1.4	-1.6	-1.7	0.2
Body mass index (BMI)	1.1	4.8	18.4	-0.4	0.9	0.5	-4.3	3.0	-3.3	1.5	0.2	1.3
Illnesses of siblings	1.1	1.6	4.8	0.6	2.2	-0.3	1.9	1.6	1.2	1.1	-0.3	0.1
Ever highly irritable/argumentative for 2 days	1.1	1.3	3.6	-0.7	1.2	0.3	-0.2	1.9	0.8	1.5	1.3	1.3
High blood pressure (siblings)	1.1	1.6	4.2	-0.3	-1.7	-0.1	-1.1	-2.0	-1.3	-1.9	-0.6	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.3	4.8	-1.7	-0.5	-1.8	2.2	-0.9	2.1	0.4	0.7	-2.0
Number of operations (self-reported)	1.1	1.6	4.3	0.0	1.4	0.7	-1.8	1.9	-2.1	0.2	-1.0	0.1
Cholesterol lowering medication	1.1	1.6	6.7	-0.1	-1.2	-0.3	-0.8	-1.1	-1.6	-1.3	-0.4	-2.6
Alzheimer’s Disease (in father)	1.0	1.1	5.4	-0.5	0.3	0.8	-2.3	1.0	-1.4	0.6	0.1	0.1
Mean Putamen Volume	1.0	1.1	3.1	-1.4	-0.5	-1.2	1.2	-0.6	1.8	0.1	1.1	0.5
Fasting Glucose	1.0	1.2	3.9	1.2	2.0	0.7	0.5	1.0	0.6	0.1	-0.4	1.7
BMI	1.0	5.8	23.0	-0.2	1.1	0.8	-4.8	2.5	-4.1	2.0	0.0	0.3
Height	1.0	20.2	48.3	-4.7	-0.1	-6.3	7.0	-0.1	6.1	0.0	2.4	-5.4
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	5.1	0.6	-0.0	1.2	-0.7	-0.0	-2.2	-0.9	-1.8	-0.2
Ever used hormone-replacement therapy (HRT)	1.0	1.2	2.5	1.0	-1.5	1.5	-1.0	-0.9	-0.9	-1.6	-0.5	0.6
Medication: Atenolol	1.0	1.2	3.1	1.3	-1.4	1.3	0.3	-0.5	-1.0	-1.8	-1.0	0.5
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	7.0	0.1	0.1	0.1	-0.4	-0.8	-1.3	-1.1	-1.2	-2.6
Hip circumference	1.0	4.5	9.3	-2.7	1.0	-2.6	-1.8	3.0	-0.4	2.9	2.1	-0.2
Pulse wave reflection index	1.0	1.2	7.5	0.8	-0.1	0.2	-2.7	0.3	-1.7	0.0	-0.0	0.1
Hypothyroidism/myxoedema (self-reported)	1.0	2.0	3.9	-1.3	1.1	-0.9	0.9	1.5	2.0	1.0	1.5	2.0
Eye problems/disorders: None of the above	1.0	1.2	3.6	-1.1	1.0	-1.9	0.0	1.2	0.9	0.2	1.3	-0.6
Medication: Blood pressure	1.0	1.8	6.1	1.2	0.4	2.5	-0.0	-0.1	-1.4	-1.5	-1.9	0.7
Leg fat mass (right)	1.0	4.1	15.0	-1.3	0.9	-0.4	-2.6	3.9	-1.3	2.4	1.3	1.8
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	5.3	0.2	0.8	0.4	2.3	-0.7	1.8	0.0	0.4	0.7
Leg fat-free mass (right)	1.0	5.3	23.3	-1.9	-0.4	-2.5	-2.3	-1.2	-2.6	-0.8	-0.5	-4.8
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	5.3	-0.1	-0.7	0.8	1.3	-0.0	1.1	0.5	0.3	2.3
Medication for cholesterol	1.0	1.6	5.1	-1.1	0.6	-1.4	0.1	1.6	1.2	2.3	1.1	-0.5
Leg predicted mass (right)	1.0	5.1	23.1	-1.8	-0.3	-2.4	-2.3	-1.2	-2.6	-0.9	-0.6	-4.8
Financial situation satisfaction	1.0	1.2	3.2	1.4	-0.7	0.2	-0.7	-0.3	-1.8	-0.7	-1.2	-1.5
Leg fat mass (left)	1.0	3.9	12.2	-1.3	0.8	-0.4	-2.9	3.5	-1.5	2.2	1.3	1.6
Body Mass Index (BMI) (2010)	0.9	1.2	3.1	0.5	-1.1	-0.0	-1.7	-0.4	-1.8	-0.6	-0.6	-1.6
Cardiovascular Disease	0.9	2.9	6.8	0.1	-2.0	0.9	-2.6	-1.9	-2.6	-1.4	-0.9	-1.2
Medication: Co-codamol	0.9	1.0	3.9	-0.9	0.1	-0.5	0.4	1.4	0.5	1.0	1.0	2.0
Taking other prescription medications	0.9	1.4	5.2	-0.4	1.5	0.6	0.8	1.6	-0.1	1.3	0.1	2.3
Age when periods started (menarche)	0.9	2.1	6.2	-1.6	-0.8	-2.5	0.3	-0.4	2.0	0.5	2.2	-0.2
Qualifications: CSEs or equivalent	0.9	1.2	3.1	-1.1	-1.4	-0.6	-0.7	0.9	0.8	1.3	1.8	0.7
Mouth/teeth dental problems	0.9	1.5	4.4	0.5	1.0	-0.3	2.1	-1.0	1.3	-1.6	-1.0	-1.2
Neuroticism score	0.9	1.9	5.6	-2.4	-0.6	-2.0	0.2	0.5	0.7	1.7	1.8	-0.1
Arm fat mass (right)	0.9	3.6	9.6	-1.8	1.0	-1.3	-2.9	3.1	-1.7	2.0	1.2	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	4.4	-1.5	-0.2	-1.0	-2.1	0.8	-1.0	0.9	1.3	-1.0
Health satisfaction	0.9	1.2	3.0	1.7	0.5	1.5	-0.2	0.1	-1.5	-0.0	-1.7	-0.0
Medication: Omeprazole	0.9	1.1	4.8	0.7	0.4	1.4	-1.1	0.2	-2.2	0.1	-1.3	0.1
Whole body fat mass	0.9	3.9	13.2	-2.0	0.9	-1.6	-2.4	3.6	-0.8	2.3	1.7	0.1
Family relationship satisfaction	0.9	1.1	3.8	1.5	0.9	1.9	0.0	0.5	-0.9	-0.0	-1.4	0.2
Leg pain on walking	0.9	1.1	4.1	0.6	0.6	2.0	-0.6	-0.5	-1.4	-1.1	-1.0	0.4
Osteoarthritis (self-reported)	0.9	1.2	4.5	-0.6	-0.1	0.0	-2.1	1.3	-1.2	1.0	0.8	1.0
Illnesses of father: None of the above (group 1)	0.9	1.1	3.7	-0.4	-0.3	0.2	0.3	1.0	1.4	1.0	1.3	1.9
Arm fat mass (left)	0.9	3.8	10.1	-1.8	0.9	-1.6	-3.1	3.2	-1.7	1.9	1.3	-0.1
Number of self-reported non-cancer illnesses	0.9	1.6	6.3	0.1	-1.1	1.3	-2.0	-0.1	-2.5	-0.2	-1.1	-0.4
Tinnitus: Yes, now most or all of the time	0.9	1.0	3.5	-0.4	1.9	0.6	-0.8	1.6	-0.7	1.0	0.2	0.9
Fractured/broken bones in last 5 years	0.9	1.2	2.2	0.9	-1.2	1.5	-1.3	-1.0	-0.9	-1.4	-0.9	-0.3
Age started oral contraceptive pill	0.9	1.2	2.9	-1.1	-0.0	-1.7	1.5	1.2	0.9	1.2	0.7	-0.3
Pain experienced in last month	0.9	1.6	4.1	-0.6	0.6	-1.6	0.9	-2.0	0.4	-1.2	-0.8	-2.0
Depressed Affect (Nagel 2018)	0.8	1.7	4.1	-1.6	-0.8	-0.6	-1.1	1.1	0.2	1.5	2.0	1.6
Crohns Disease (2012)	0.8	1.3	4.0	-0.4	1.6	0.1	0.5	2.0	0.3	1.4	0.5	1.8
Neuroticism (2016)	0.8	1.1	3.1	1.3	-1.2	1.8	1.1	0.5	0.7	0.1	-0.6	1.2
Ulcerative Colitis	0.8	1.2	2.8	-1.4	0.8	-0.8	-1.2	1.1	0.6	1.3	1.7	0.5
Lung FEV1/FVC ratio	0.8	4.3	10.7	2.0	1.5	2.9	-2.3	0.2	-3.3	-1.1	-2.2	1.5
Number of treatments/medications taken	0.8	1.4	4.2	0.5	-0.9	2.0	-1.6	-0.6	-2.1	0.1	-0.9	0.2
Leg fat-free mass (left)	0.8	4.1	19.4	-1.8	-0.1	-2.3	-2.0	-0.6	-2.2	-0.5	-0.3	-4.4
Serious illness, injury or assault to yourself	0.8	0.9	2.9	-1.0	0.3	-1.7	-0.9	0.4	-0.1	0.9	0.8	-1.3
Stomach or abdominal pain in last month	0.8	1.0	3.2	-0.6	0.7	0.8	-0.1	0.5	1.0	1.5	0.9	1.8
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	2.3	-0.0	-0.7	0.0	-1.1	1.5	-1.5	1.2	-0.5	0.6
Leg predicted mass (left)	0.8	4.1	19.7	-1.8	-0.1	-2.3	-1.9	-0.6	-2.2	-0.5	-0.4	-4.4
Alcohol usually taken with meals	0.8	1.2	3.5	1.4	-0.4	1.0	1.9	-0.1	1.0	-1.2	-0.7	1.2
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	3.2	0.1	-0.2	-0.9	-1.8	-1.5	-1.3	-0.9	-0.2	-1.4
Had other major operations	0.8	1.0	2.0	-1.4	0.4	-1.1	0.4	1.0	0.7	1.4	1.1	0.5
Heart attack	0.8	1.0	2.6	-1.3	0.4	-0.8	-0.0	1.6	0.3	1.6	1.0	0.5
Medication: Ramipril	0.8	1.1	5.0	-0.9	-0.8	1.0	0.4	0.8	0.7	-0.4	0.9	2.2
Tense / ‘highly strung’	0.8	1.3	5.0	-1.7	-0.3	-2.2	-0.3	-0.1	0.5	1.1	1.2	-0.7
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	4.0	-1.5	-0.2	-2.0	1.4	0.8	1.3	0.2	0.7	-0.0
Chronic bronchitis/emphysema (mother)	0.8	0.9	2.1	-0.0	-0.7	0.3	-1.3	1.4	-0.9	1.2	0.5	1.2
Exposure to tobacco smoke outside home	0.8	1.1	2.6	-1.6	-0.4	-1.6	0.4	0.1	1.1	1.2	1.4	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	3.1	-1.0	-1.0	-1.8	-1.2	0.6	-0.4	0.7	1.1	0.5
Medication: Seretide 50 evohaler	0.8	0.9	3.2	-0.9	-1.2	-1.2	-1.8	0.3	-0.9	-0.2	0.2	-0.3
Pulse rate, automated reading	0.8	2.5	8.7	-0.5	3.0	0.4	1.3	1.9	1.3	1.6	0.3	1.9
Illnesses of siblings: Diabetes	0.8	1.0	5.2	-0.8	0.4	0.8	-1.2	0.4	-0.1	0.3	0.8	2.3
Mood swings	0.8	1.5	4.4	-2.1	-0.8	-1.2	-0.7	0.4	0.3	1.6	1.9	-0.3
Commuting to job workplace: Public transport	0.8	1.0	3.5	0.5	-0.9	0.7	0.4	-1.2	-1.1	-0.5	-0.7	-1.9
Pain type(s) experienced in last month: Hip pain	0.8	1.0	4.5	0.4	1.1	1.6	0.0	0.4	0.0	0.1	0.3	2.1
Unable to work because of sickness or disability	0.8	1.1	2.6	-0.1	-1.6	1.2	-1.0	0.6	-1.3	-0.8	-0.8	1.1
Alcohol drinker status: Previous	0.8	0.9	4.1	-0.7	-1.4	-0.0	-2.0	-0.1	-0.8	0.2	0.8	-0.1
Major Depression (MDD)	0.7	0.8	1.8	-0.9	-0.9	-1.2	-0.6	1.3	-0.6	1.0	0.9	-0.2
Allergy or Eczema	0.7	1.9	11.8	-0.1	1.3	-0.6	3.4	0.8	1.0	1.1	-0.7	0.0
Supplements: Glucosamine	0.7	0.9	4.1	0.4	-0.2	-0.3	0.7	-1.6	0.8	-0.3	0.2	-2.0
Waist circumference	0.7	2.4	9.7	-0.0	0.5	0.8	-3.1	1.7	-2.8	0.5	-0.3	0.1
Trunk fat-free mass	0.7	3.8	15.4	-0.6	-1.2	-0.7	-1.4	-2.3	-2.2	-1.6	-1.3	-3.9
Father’s age at death	0.7	1.0	2.8	-0.3	-1.1	-1.1	1.6	0.3	1.7	-0.3	0.7	-0.4
Depression (self-reported)	0.7	0.9	2.9	-0.5	-0.9	-0.2	-1.7	1.4	-1.2	0.4	0.4	0.1
Length of working week for main job	0.7	0.7	4.2	0.1	0.3	0.3	2.0	0.4	0.6	1.0	-0.6	0.6
Birth weight	0.7	1.6	6.7	0.6	1.4	-0.2	0.2	-1.6	-0.3	-1.2	-1.2	-2.6
Wheeze or whistling in the chest in last year	0.7	1.3	6.6	-0.4	-1.5	0.1	-2.6	-0.2	-1.3	0.3	0.7	-0.5
Medication for pain relief, constipation, heartburn	0.7	1.2	3.5	-0.0	0.0	-1.5	1.3	-1.2	1.0	-1.9	0.1	-1.2
Number of full sisters	0.7	0.8	2.7	-1.6	-0.6	-0.8	-1.3	0.5	0.1	0.1	1.0	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	3.0	0.8	1.1	0.3	0.8	1.2	0.4	0.5	0.2	1.7
Whole body fat-free mass	0.7	4.0	17.3	-1.0	-0.9	-1.2	-1.8	-1.9	-2.5	-1.2	-1.0	-4.2
Osteoporosis (self-reported)	0.7	0.9	2.6	1.3	0.8	1.6	0.8	-0.0	-0.6	-0.3	-1.2	0.5
Whole body water mass	0.7	4.0	16.6	-1.0	-1.0	-1.3	-2.0	-1.7	-2.5	-1.2	-0.9	-4.1
Diastolic blood pressure, automated reading	0.7	2.1	9.6	0.1	-0.2	1.9	-0.8	1.6	0.8	1.0	1.0	3.1
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.1	-1.4	0.3	-0.9	-0.3	1.4	0.2	1.4	1.1	0.1
HbA1C	0.6	0.7	2.9	-0.3	0.3	-0.3	0.1	0.7	0.7	1.7	1.0	1.2
Lupus	0.6	0.9	2.6	-0.8	1.0	-1.2	0.0	-1.2	0.3	-0.7	0.3	-1.6
Type 2 Diabetes (T2D) (2012)	0.6	0.6	2.6	0.3	0.8	-0.2	0.5	-0.2	1.6	-0.3	0.9	1.1
Systolic Blood Pressure	0.6	3.0	11.4	-0.4	-1.1	0.9	3.4	-1.8	2.9	-1.1	0.2	0.5
Type 2 Diabetes (T2D) (2018)	0.6	1.0	4.6	0.7	-0.8	1.1	-0.8	-0.6	-0.7	-0.9	0.1	2.1
Frequency of depressed mood in last 2 weeks	0.6	0.8	3.5	-0.0	0.3	-0.1	-1.9	-0.3	-1.6	-0.5	-0.3	-0.7
Diabetes (father)	0.6	0.8	2.0	1.1	-0.5	1.4	1.3	-0.5	-0.0	-0.7	-0.7	0.9
Average weekly fortified wine intake	0.6	0.7	2.1	1.4	-1.0	1.3	0.5	-0.6	0.1	-0.3	-0.8	0.4
Fed-up feelings	0.6	1.0	2.6	-0.8	0.4	-0.1	0.0	0.6	1.0	1.6	1.6	1.3
High blood pressure (mother)	0.6	0.8	1.9	-0.8	-1.4	0.5	1.3	-0.6	1.3	-0.1	0.8	0.2
Forced vital capacity (FVC)	0.6	2.3	10.2	-1.4	0.2	-1.8	0.4	-2.1	0.2	-0.7	0.2	-3.2
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	3.7	-0.4	0.2	-0.5	-1.9	1.0	-0.6	0.8	0.8	0.4
Financial difficulties in last 2 years	0.6	0.9	3.0	0.1	-0.8	0.6	-1.7	0.8	-1.6	0.6	-0.2	0.6
Pain all over the body in last month	0.6	0.7	2.5	-0.7	-0.7	-0.6	-1.6	0.2	-1.0	0.7	0.7	0.4
Number of live births	0.6	0.8	4.2	0.3	0.2	1.4	-0.8	0.2	-0.3	0.1	-0.1	2.0
Noisy workplace	0.6	0.7	1.8	-1.3	0.7	-1.3	-0.5	0.6	-0.0	0.7	1.0	-0.6
Illnesses of mother	0.6	0.8	2.9	-0.3	-0.1	-1.7	-0.9	-1.0	-0.3	-0.0	0.4	-1.3
Trunk predicted mass	0.6	3.7	14.6	-0.5	-1.2	-0.6	-1.4	-2.3	-2.3	-1.6	-1.3	-3.8
Peak expiratory flow (PEF)	0.6	1.5	5.0	-0.9	0.5	-1.6	-1.6	-0.3	-1.4	-0.2	0.0	-2.2
Forced vital capacity (FVC), Best measure	0.6	2.2	9.5	-1.4	0.1	-2.0	0.9	-1.5	0.8	-0.6	0.3	-3.1
Arm fat-free mass (right)	0.6	2.9	7.5	-0.8	-1.5	-0.5	-2.7	-1.6	-2.4	-0.8	-0.4	-2.6
Arm predicted mass (right)	0.6	2.9	6.4	-0.4	-1.4	-0.0	-2.5	-1.7	-2.5	-1.1	-0.8	-2.5
Comparative height size at age 10	0.6	3.5	18.0	-0.5	0.4	-2.3	1.7	-1.1	0.0	-1.4	-1.2	-4.2
Ever had bowel cancer screening	0.6	0.7	1.4	-1.0	0.3	-1.0	0.2	0.9	0.9	1.0	1.2	-0.1
Friendships satisfaction	0.6	0.8	2.7	-0.2	1.6	0.6	-1.5	0.6	-1.0	0.2	-0.3	-0.6
Mineral and other dietary supplements	0.6	0.8	2.5	0.1	1.1	0.4	0.3	1.6	0.0	0.9	-0.3	1.5
Wears glasses or contact lenses	0.6	0.7	2.3	-1.5	-0.4	-0.7	-0.1	0.9	1.2	0.4	0.9	0.1
Medication: Paracetamol	0.6	0.9	3.2	-0.3	-0.0	0.8	-1.8	0.0	-0.3	1.2	1.1	1.3
Average weekly beer plus cider intake	0.6	0.8	4.2	0.4	2.0	1.1	0.8	-0.4	0.2	-0.2	-0.6	0.6
Depression (Nagel 2018)	0.5	0.7	3.5	-0.7	0.4	-0.5	-1.9	0.0	-1.1	0.2	0.6	0.5
HDL Cholesterol	0.5	0.9	2.6	0.7	-1.0	0.2	-0.1	-1.2	-0.7	-1.6	-0.9	-1.1
Blood White Count	0.5	3.5	12.4	1.0	-0.2	2.2	3.5	0.1	2.2	-0.6	-0.4	2.8
Smoking Status	0.5	1.2	4.1	0.9	1.0	0.3	-0.7	1.7	0.7	0.3	1.1	2.0
Relative age voice broke	0.5	0.8	3.5	-0.7	-1.9	-0.5	-0.4	-0.5	0.8	-0.9	0.8	-0.4
Hayfever, allergic rhinitis or eczema	0.5	1.1	7.3	0.3	0.2	-0.0	2.7	-0.5	0.3	-0.0	-1.0	-1.0
Multivitamins +/- minerals	0.5	0.7	1.9	0.5	1.2	1.2	0.2	0.2	0.7	0.4	0.5	1.4
Fluid intelligence score	0.5	1.0	5.6	-0.2	-0.4	-0.9	-1.0	-0.6	-0.8	-0.3	-0.0	-2.4
Weight	0.5	2.6	4.4	-2.0	0.7	-1.8	-2.1	2.1	-1.4	1.4	0.9	-1.4
Happiness	0.5	0.7	3.5	0.5	0.8	-0.3	-0.2	1.9	-0.9	0.2	-0.6	-0.5
Qualifications: A levels/AS levels or equivalent	0.5	1.1	3.7	0.1	-0.3	-1.3	1.6	0.1	-0.5	-0.2	-1.1	-1.9
Mouth/teeth dental problems: Dentures	0.5	0.8	2.2	-1.2	-0.6	-0.1	-1.5	0.0	-0.3	0.9	1.2	1.1
Lung cancer (father)	0.5	0.6	1.6	-0.8	-0.1	0.2	1.1	0.2	0.6	1.3	0.3	1.2
Birth weight of first child	0.5	0.9	4.8	-0.7	0.5	-1.3	0.5	0.7	-0.1	-0.1	0.1	-2.2
Pulse wave peak to peak time	0.5	0.6	2.7	-0.6	0.2	-0.6	0.6	-1.0	-0.4	-0.2	-0.5	-1.6
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.0	-1.2	-0.8	-0.7	-0.3	0.3	0.6	0.5	1.4	0.5
Medication: Allopurinol	0.5	0.7	2.0	-0.6	-1.4	-0.6	-0.8	-0.1	0.3	0.1	0.8	1.4
Medication: Aspirin	0.5	0.7	2.0	-0.4	-0.6	0.5	-1.4	-0.8	-1.3	0.0	-0.4	-1.2
Supplements: Vitamin C	0.5	0.6	1.3	-0.8	-0.8	-0.9	0.4	-0.4	0.8	1.1	1.0	0.1
Knee pain experienced in last month	0.5	0.8	2.7	-0.6	-0.1	0.0	-1.1	1.6	-0.2	0.8	1.4	0.7
Average weekly red wine intake	0.5	0.7	1.9	-0.7	-0.7	-1.3	0.9	-0.6	1.4	-0.0	0.8	-0.3
Hearing aid user	0.5	0.6	1.7	-0.4	-1.3	-0.1	-1.2	0.3	-0.8	1.0	0.0	-0.7
Basal metabolic rate	0.5	3.0	12.8	-1.3	-0.5	-1.5	-2.0	-0.8	-2.3	-0.6	-0.5	-3.6
Ever depressed for a whole week	0.5	0.6	3.0	1.1	-0.0	1.7	-0.2	0.9	-0.1	0.1	-0.7	0.3
Heel T-Score	0.4	3.4	14.4	2.1	-0.3	2.8	1.1	0.7	0.7	-0.0	-1.1	3.8
Relative age of first facial hair	0.4	0.8	1.9	1.2	-0.6	0.7	-1.4	-1.1	-0.2	-1.3	-0.0	-0.1
Systolic blood pressure, automated reading	0.4	1.1	3.5	-0.2	-1.3	0.6	1.9	1.0	1.7	-0.2	0.6	0.9
Medication for hormone replacement therapy	0.4	0.5	1.7	-0.0	1.1	-0.3	-0.1	0.0	-0.5	-0.8	-0.3	1.3
Hand grip strength (right)	0.4	1.2	3.6	1.2	-0.3	0.4	-0.3	-1.9	-0.4	-1.4	-1.0	-1.4
Allergy	0.4	1.0	6.1	-0.2	-0.7	0.2	-2.5	-0.5	-0.3	-0.8	0.5	1.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	5.4	-0.5	0.5	-0.8	-0.4	-1.8	-0.6	-1.2	-0.6	-2.3
Prospective memory result	0.4	0.4	1.3	0.2	-0.7	0.1	1.1	-0.9	0.9	0.2	0.2	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	6.6	-0.8	0.6	-1.3	-0.4	-1.4	-0.3	-0.8	-0.2	-2.6
Pulse wave Arterial Stiffness index	0.4	0.4	1.8	0.4	-0.2	0.3	-0.1	0.8	0.9	0.2	0.6	1.3
Shortness of breath walking on level ground	0.4	0.4	1.6	0.1	0.2	1.3	-0.8	0.9	-0.5	0.0	-0.0	0.8
Heart disease (mother)	0.4	0.5	1.5	0.9	-0.0	0.3	-0.5	1.0	-1.2	-0.5	-0.8	-0.5
Miserableness	0.4	0.7	2.7	-1.2	0.5	-0.2	-0.0	0.7	-0.3	1.6	1.2	0.0
Ever taken oral contraceptive pill	0.4	0.4	1.1	0.6	-0.8	1.0	-0.2	-0.1	-0.9	0.2	-0.5	-0.6
Medication: Bendroflumethiazide	0.4	0.5	2.3	0.5	0.5	1.5	0.4	-0.2	-0.4	-0.7	-0.8	0.8
Arm fat-free mass (left)	0.4	1.8	4.3	-1.2	-1.2	-0.6	-2.0	-0.9	-2.0	-0.2	-0.0	-2.1
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.1	0.7	0.7	0.9	0.1	0.3	-0.8	0.5	-1.1	0.1
Commuting to job workplace: Cycle	0.4	0.4	2.1	-0.3	-1.5	-0.3	-0.2	0.1	-0.9	-0.3	-0.5	-0.6
Intelligence (Savage-Jansen 2018)	0.3	1.0	3.8	-1.2	0.2	-1.4	-0.0	0.6	0.2	0.9	0.7	-1.9
Hypothyroidism (self reported)	0.3	0.7	1.6	-1.3	0.4	-0.8	-0.1	0.9	1.0	0.4	1.1	0.8
Respiratory disease	0.3	0.8	2.4	-0.2	-1.5	-0.6	0.2	-0.2	0.4	1.3	1.1	-1.0
Hand grip strength (left)	0.3	0.9	2.5	0.5	-0.3	-0.4	0.0	-1.6	-0.1	-1.4	-0.8	-1.5
Medication: Metformin	0.3	0.4	1.5	-0.2	-0.2	0.3	-0.7	-0.6	-0.9	-0.7	-0.3	1.2
Past tobacco smoking	0.3	0.5	1.5	-0.5	0.7	0.5	0.6	-0.8	-0.6	0.3	-1.2	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	3.2	-0.3	0.3	-0.2	-0.3	0.5	-0.6	0.6	0.4	1.8
Hair/balding pattern: Pattern 3	0.3	0.5	1.8	0.5	0.2	0.6	-0.2	0.2	-0.9	-0.1	-1.0	-1.4
Asthma	0.3	0.7	1.3	-0.3	-0.8	-1.1	0.2	1.0	-0.1	1.2	0.9	-0.9
Breastfed as a baby	0.3	0.4	1.0	-0.5	0.3	-0.7	0.9	0.1	0.7	-1.0	0.4	-0.3
Loud music exposure frequency	0.3	0.3	1.0	-0.3	-1.0	-0.5	0.1	0.1	0.3	0.5	0.6	-0.9
Gout (self-reported)	0.3	0.4	2.1	0.8	-0.1	0.6	0.0	-0.4	0.4	-0.4	-0.1	1.4
Number of full brothers	0.3	0.4	1.6	-0.6	0.3	-0.4	-0.2	0.5	0.8	0.4	1.3	0.4
Worry too long after embarrassment	0.3	0.6	1.7	-1.0	-1.3	-1.2	0.3	-0.5	0.2	-0.3	0.1	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.8	0.2	-0.6	0.4	0.2	-1.3	0.6	-0.5	-0.1	0.6
Mean time to correctly identify matches	0.3	0.5	1.5	1.1	0.1	0.2	-0.8	0.5	-1.2	-0.2	-0.8	-0.2
Smoking status: Previous	0.3	0.5	1.4	1.2	-0.9	0.3	-0.7	-0.4	-0.1	-1.1	0.1	-0.1
Asthma (self-reported)	0.3	0.6	1.2	-0.1	-1.0	-0.8	0.3	0.9	0.0	1.1	1.0	-0.8
Ever smoked	0.3	0.6	1.9	0.3	-0.5	-0.9	-0.1	1.4	0.7	0.4	1.2	0.4
Risk taking	0.3	0.5	1.5	-1.2	-0.6	-1.2	-0.0	-0.2	0.5	0.0	1.1	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	1.1	0.8	0.6	1.1	0.6	0.3	0.5	-0.0	-0.2	0.2
Arm predicted mass (left)	0.3	1.7	4.0	-1.0	-1.3	-0.5	-1.8	-1.0	-1.9	-0.3	-0.2	-2.0
Reaction Time	0.2	0.4	1.0	0.9	0.5	-0.1	-0.0	0.7	-1.0	0.3	-0.8	-0.0
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.2	-0.8	-0.5	-0.6	-0.9	1.1	-0.3	0.9	0.6	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.4	-0.5	0.7	-0.1	-0.7	-0.2	-0.3	0.1	0.2	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	3.2	0.3	0.2	0.1	-0.4	0.5	-0.1	-0.3	-0.1	1.8
Number of incorrect matches in round	0.2	0.4	2.4	0.6	-1.5	-0.3	-0.4	-0.7	-0.3	0.2	0.1	-0.1
Worrier / anxious feelings	0.2	0.4	1.2	-0.5	1.0	0.3	1.1	-0.4	0.6	0.4	-0.1	0.6
Hair/balding pattern: Pattern 4	0.2	0.4	1.3	-1.1	0.9	-0.5	-0.3	-0.2	-0.1	0.7	0.6	-0.3
Blood clot in the leg (DVT)	0.2	0.2	1.1	0.7	0.4	1.0	0.3	-0.1	0.4	-0.1	-0.1	-0.0
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.0	0.7	-0.3	-0.1	0.7	-0.1	0.1	0.2	-1.0	-0.3
Emphysema/chronic bronchitis	0.2	0.2	0.7	0.4	-0.8	0.4	-0.3	0.3	-0.1	0.7	-0.1	0.2
Eye problems/disorders: Cataract	0.2	0.2	0.3	0.5	0.5	0.6	-0.6	0.6	-0.4	0.5	-0.2	0.3
Illnesses of father: High blood pressure	0.2	0.3	0.7	0.3	-0.4	0.8	-0.7	-0.8	-0.3	-0.5	-0.3	-0.2
Alcohol drinker status: Never	0.2	0.2	0.6	-0.5	-0.4	-0.4	-0.5	-0.3	-0.6	-0.8	-0.4	-0.0
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	-0.0	-0.6	0.2	0.1	-0.2	0.2	-0.5	-0.2	-0.2
Hearing difficulty/problems with background noise	0.1	0.1	0.6	-0.5	-0.0	-0.0	-0.2	-0.8	-0.2	0.2	0.3	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.3	0.6	0.1	0.4	-0.7	-0.2	-0.4	-0.6	-0.4	1.1
Basal cell carcinoma (self-reported)	0.1	0.2	0.8	-0.1	-0.2	-0.2	-0.9	0.2	-0.3	-0.4	0.0	-0.5
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lung FVC	0.0	0.2	0.6	-0.0	0.8	-0.1	0.2	0.1	0.3	0.6	0.3	0.4
Hair Pigment	0.0	1.4	4.9	1.5	-0.4	2.2	0.1	0.0	-0.8	-0.1	-0.9	2.0
Tanning	0.0	0.1	0.2	0.3	-0.3	0.2	-0.1	0.5	-0.4	-0.3	-0.1	0.2

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