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chr2:102,118,712-104,027,106

Best TWAS P=7.25e-74 · Best GWAS P=8.28e-60 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	SLC9A2	0.17	0.10	lasso	4	0.11	4.7e-13	7.8	7.8	7.0e-15	-0.25	1.00	0.00	TRUE
2	GTEx	Colon Transverse	IL18R1	0.14	0.00	enet	41	0.00	2.1e-01	3.9	11.9	1.7e-32	-0.41	0.04	0.48	TRUE
3	GTEx	Whole Blood	IL18R1	0.06	0.00	enet	14	0.01	2.1e-02	-13.7	8.2	3.3e-16	-0.25	0.17	0.05	FALSE
4	NTR	Blood	IL18R1	0.05	0.02	bslmm	582	0.02	5.1e-07	4.9	6.7	1.9e-11	-0.30	0.99	0.00	FALSE
5	NTR	Blood	IL18RAP	0.14	0.16	lasso	7	0.19	1.1e-59	10.5	-6.0	1.4e-09	0.27	1.00	0.00	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	IL1RL2	0.08	0.02	enet	33	0.03	2.3e-04	6.6	-9.5	1.6e-21	0.47	0.17	0.19	FALSE
7	YFS	Blood	IL18RAP	0.41	0.55	bslmm	562	0.62	4.2e-269	10.5	-6.8	9.5e-12	0.33	1.00	0.00	FALSE
8	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	IL1RL1	0.04	0.03	lasso	7	0.03	8.1e-04	-13.7	-14.4	3.5e-47	0.52	0.25	0.11	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	IL18R1	0.05	0.01	blup	108	0.03	1.8e-07	-13.7	9.1	1.0e-19	-0.08	0.99	0.00	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	IL1RL1	0.02	0.01	blup	78	0.01	1.5e-03	14.1	-15.4	2.5e-53	0.64	0.15	0.26	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IL1RL1	0.04	0.04	lasso	8	0.04	1.7e-05	-16.3	-17.4	6.3e-68	0.93	0.01	0.99	TRUE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL18R1	0.06	0.01	blup	108	0.04	2.6e-05	-1.2	-8.1	6.4e-16	0.62	0.02	0.84	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL18RAP	0.03	0.02	blup	94	0.02	1.2e-03	-13.7	13.7	6.3e-43	-0.64	0.01	0.91	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL1RL1	0.08	0.08	enet	9	0.08	1.2e-09	-16.3	-18.1	1.9e-73	0.94	0.00	1.00	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL1RL2	0.04	0.04	enet	5	0.03	1.9e-04	-12.1	-12.9	2.6e-38	0.69	0.06	0.41	FALSE
16	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	IL1RL1	0.18	0.06	blup	78	0.15	3.7e-09	14.1	-17.9	1.5e-71	0.83	0.01	0.99	TRUE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	IL1RL1	0.03	0.01	blup	78	0.02	4.7e-03	-15.4	-18.2	7.2e-74	0.85	0.01	0.95	TRUE
18	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	IL1RL1	0.19	0.05	blup	78	0.10	7.1e-05	14.3	-16.8	2.3e-63	0.64	0.13	0.66	TRUE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	IL1R1	0.36	0.19	enet	28	0.23	1.1e-23	-11.0	7.6	2.4e-14	-0.51	0.70	0.30	TRUE
20	The Cancer Genome Atlas	Thyroid Carcinoma	IL1RL1	0.05	0.03	enet	6	0.03	9.7e-04	-16.3	-16.3	5.6e-60	0.95	0.00	0.99	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	SLC9A2	0.05	0.01	blup	93	0.02	8.6e-03	6.7	6.7	2.3e-11	-0.17	0.02	0.82	TRUE