TWAS hub - SLC9A2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.170	0.046	2.1e-07	0.096	0.060	0.096	0.094	0.108	9.1e-12	8.6e-08	9.4e-12	1.7e-11	4.7e-13
2	TCGA	Thyroid Carcinoma	0.054	0.029	4.2e-03	0.010	0.016	0.013	NA	0.011	3.4e-02	8.7e-03	1.8e-02	NA	2.8e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood Eosinophil Count	28.2	217.0	292.4	17.1	11.9
Asthma	23.9	47.2	50.6	7.1	6.6
Respiratory disease	23.6	52.6	60.5	7.8	6.7
Asthma (self-reported)	22.3	44.3	47.2	6.9	6.4
Allergy	20.7	47.7	52.3	-7.2	-6.6
Hayfever/allergic rhinitis (self-reported)	18.9	25.0	26.1	5.1	4.9
Medication: Ventolin 100micrograms inhaler	15.5	19.8	24.1	4.9	4.0
Allergy or Eczema	12.6	33.1	33.9	5.7	5.8
Alcohol drinker status: Never	11.4	13.6	17.6	3.1	4.2
Hayfever, allergic rhinitis or eczema	10.9	23.8	24.1	4.9	4.8
Wheeze or whistling in the chest in last year	10.7	19.2	22.5	4.7	4.0
Number of treatments/medications taken	7.6	13.7	17.6	3.1	4.2
Taking other prescription medications	7.1	10.9	13.7	2.8	3.7
Number of self-reported non-cancer illnesses	6.3	10.9	11.0	3.3	3.3
Medication for pain relief, constipation, heartburn	4.8	8.2	10.1	-2.5	-3.2
Lung FEV1/FVC ratio	4.6	23.4	23.7	-4.9	-4.8
Mother’s age at death	4.6	5.7	6.6	-2.6	-2.2
Pulse rate, automated reading	3.9	12.6	13.6	3.4	3.7
Worry (Nagel 2018)	3.6	7.7	9.8	-2.4	-3.1
Chest pain or discomfort	3.4	4.9	6.5	2.6	1.8
Neuroticism (Nagel 2018)	3.3	7.7	9.7	-2.4	-3.1
Eye problems/disorders: Glaucoma	3.3	3.9	5.1	1.6	2.3
Ever smoked	3.3	5.7	8.5	-1.7	-2.9
Pulse rate	3.2	5.4	7.2	2.7	1.9
Lung cancer (father)	3.2	3.7	4.1	2.0	1.8
Glaucoma (self-reported)	3.2	3.7	5.2	1.5	2.3
Qualifications: NVQ or HND or HNC or equivalent	3.2	3.9	4.6	1.8	2.1
Long-standing illness, disability or infirmity	3.2	4.8	7.5	1.5	2.7
Pain type(s) experienced in last month: Hip pain	3.2	4.0	5.9	2.4	1.4
Medication: Paracetamol	3.1	4.8	6.0	1.9	2.4
Number of operations (self-reported)	3.1	4.6	6.8	1.6	2.6
Forced expiratory volume in 1-second (FEV1), Best measure	3.0	9.5	12.4	-2.6	-3.5
Medication: Paracetamol	2.9	4.8	5.5	2.0	2.3
Birth weight	2.9	6.3	8.1	-2.1	-2.8
Leg fat percentage (right)	2.9	10.6	10.6	3.3	3.2
Guilty feelings	2.9	4.3	4.6	-2.1	-2.0
Waist circumference	2.7	9.7	9.8	3.1	3.1
Commuting to job workplace: Cycle	2.7	3.3	3.6	-1.9	-1.7
Age at First Birth	2.5	3.6	3.9	1.8	2.0
HDL Cholesterol	2.5	4.2	4.8	1.9	2.2
Seen a psychiatrist for nerves, anxiety, tension or depression	2.5	3.3	4.8	-2.2	-1.3
Pulse wave peak to peak time	2.5	2.9	3.8	-1.4	-2.0
Schizophrenia (2018)	2.4	4.9	7.4	-1.6	-2.7
Medication: Lansoprazole	2.4	2.7	2.8	1.6	1.7
Pulse wave Arterial Stiffness index	2.4	2.8	3.6	1.4	1.9
Average weekly red wine intake	2.4	3.6	3.6	-1.9	-1.9
Leg fat percentage (left)	2.4	8.6	8.7	2.9	3.0
Crohns Disease (2017)	2.3	5.0	7.8	-2.8	-1.5
Hair/balding pattern: Pattern 2	2.3	2.9	3.5	1.9	1.5
Eye problems/disorders: Diabetes related eye disease	2.2	2.4	3.2	1.2	1.8
Heart attack/myocardial infarction (self-reported)	2.2	2.8	3.9	1.3	2.0
Bipolar Disorder or Schizophrenia	2.1	5.1	7.0	-1.8	-2.6
Had other major operations	2.1	2.6	4.7	0.7	2.2
Medication: Ibuprofen (e.g. Nurofen)	2.1	2.6	2.7	1.6	1.6
Illnesses of siblings: Diabetes	2.1	2.6	3.2	-1.4	-1.8
Supplements: Calcium	2.1	2.3	3.2	-1.8	-1.2
Irritable Bowel Disease (IBD)	2.0	4.8	8.2	-2.9	-1.2
Heart attack	2.0	2.6	3.5	1.3	1.9
Forced expiratory volume in 1-second (FEV1)	2.0	6.7	10.0	-1.9	-3.2
Triglycerides	1.9	3.1	5.3	-2.3	-1.0
Severe depression (siblings)	1.9	2.1	2.4	-1.3	-1.6
Past tobacco smoking	1.9	3.5	4.8	1.5	2.2
Birth weight of first child	1.9	3.4	5.9	-0.9	-2.4
Smoking status: Previous	1.9	2.8	3.2	-1.5	-1.8
Schizophrenia (2014)	1.8	3.9	5.7	-1.5	-2.4
Medication: Allopurinol	1.8	2.4	3.2	-1.8	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	2.8	1.7	1.0
Friendships satisfaction	1.8	2.3	3.0	-1.2	-1.7
Verbal and Numeric Reasoning (VNR)	1.7	4.0	4.9	-1.8	-2.2
Waist Hip Ratio (WHR)	1.7	7.6	9.5	2.4	3.1
Cardiovascular Disease	1.7	5.7	7.2	2.1	2.7
Health satisfaction	1.7	2.3	2.5	1.6	1.4
Alcohol intake frequency.	1.7	4.0	4.3	2.1	1.9
Overall health rating	1.7	3.6	3.7	1.9	1.9
Depressed Affect (Nagel 2018)	1.6	3.5	4.2	-1.6	-2.1
Ever used hormone-replacement therapy (HRT)	1.6	2.0	2.4	-1.5	-1.3
Multivitamins +/- minerals	1.6	2.0	2.4	1.2	1.6
Fluid intelligence score	1.6	3.3	4.0	-1.6	-2.0
Leg fat mass (right)	1.6	6.3	7.0	2.6	2.4
Diabetes (mother)	1.5	1.9	3.5	0.6	1.9
Father’s age at death	1.5	2.0	3.5	-1.9	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.7	2.6	-1.6	-0.9
Knee pain experienced in last month	1.5	2.4	4.6	0.5	2.1
Medication: Atorvastatin	1.5	1.8	2.4	1.5	1.1
Leg fat mass (left)	1.5	5.7	6.5	2.5	2.2
Depression (Nagel 2018)	1.4	2.1	2.3	-1.5	-1.4
Qualifications: CSEs or equivalent	1.4	1.9	3.7	1.9	0.0
Nervous feelings	1.4	2.5	2.8	-1.5	-1.7
High cholesterol (Self-reported)	1.4	2.6	3.2	1.8	1.4
Major Depression (MDD)	1.3	1.6	2.6	-1.6	-0.8
Medication: Atenolol	1.3	1.7	1.9	-1.2	-1.4
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	2.0	-1.4	-1.4
Prospective memory result	1.3	1.6	1.8	-1.3	-1.2
Number of full brothers	1.3	1.6	1.8	1.2	1.3
Shortness of breath walking on level ground	1.3	1.5	2.4	0.8	1.5
Miserableness	1.3	2.3	2.7	-1.4	-1.6
Alzheimer’s Disease (including proxy)	1.2	1.8	2.4	-1.1	-1.6
Neuroticism	1.2	2.8	3.5	-1.5	-1.9
Supplements: Glucosamine	1.2	1.5	1.6	1.3	1.2
Body mass index (BMI)	1.2	5.0	5.2	2.3	2.2
Body fat percentage	1.2	4.8	5.2	2.1	2.3
Medication: Blood pressure	1.2	2.1	3.1	1.1	1.8
Whole body fat mass	1.2	4.9	5.4	2.3	2.1
Suffer from ‘nerves’	1.2	1.9	3.8	-0.3	-1.9
Leg pain on walking	1.2	1.5	1.9	1.4	1.0
Osteoporosis (self-reported)	1.2	1.5	1.8	-1.3	-1.1
Diastolic blood pressure, automated reading	1.2	3.8	5.1	1.6	2.3
Heart disease (siblings)	1.2	1.5	1.6	1.2	1.3
Fasting Glucose	1.1	1.3	2.1	0.7	1.4
Medication for hormone replacement therapy	1.1	1.2	2.2	-1.5	-0.4
Stomach or abdominal pain in last month	1.1	1.4	2.6	1.6	0.4
Gout (self-reported)	1.1	1.5	2.2	-1.5	-0.8
Chronic bronchitis/emphysema (mother)	1.1	1.3	1.7	0.9	1.3
Forced vital capacity (FVC), Best measure	1.1	4.0	6.1	-1.4	-2.5
Medication: Ibuprofen	1.1	1.3	1.8	0.9	1.3
Reaction Time	1.0	1.9	2.0	1.4	1.4
LDL Cholesterol	1.0	1.6	2.3	-1.5	-1.0
Had menopause	1.0	1.3	2.5	-1.6	0.0
Medication: Seretide 50 evohaler	1.0	1.2	1.5	0.9	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	1.5	-1.2	-1.0
Had major operations	1.0	1.2	1.8	0.7	1.3
Handedness (chirality/laterality): Left-handed	1.0	1.3	2.2	-0.6	-1.5
Arm fat mass (left)	1.0	4.2	5.0	2.2	1.8
Cholesterol lowering medication	1.0	1.4	2.0	1.0	1.4
Intelligence (Savage-Jansen 2018)	0.9	2.7	3.6	-1.3	-1.9
Lupus	0.9	1.4	1.8	-1.0	-1.4
Ulcerative Colitis	0.9	1.3	2.5	-1.6	-0.2
Average weekly spirits intake	0.9	1.1	1.6	-0.7	1.3
Ever had hysterectomy (womb removed)	0.9	1.1	2.1	0.2	1.4
Diabetes (father)	0.9	1.1	1.4	0.9	1.2
Serious illness, injury or assault to yourself	0.9	1.1	2.2	0.1	1.5
Trunk fat mass	0.9	3.7	4.2	2.0	1.8
Forced vital capacity (FVC)	0.9	3.3	5.9	-0.8	-2.4
Time employed in main current job	0.9	1.0	1.1	1.0	1.0
Worrier / anxious feelings	0.9	1.6	2.0	-1.1	-1.4
Arm fat mass (right)	0.9	3.8	4.7	2.2	1.7
Angina (self-reported)	0.9	1.2	2.0	0.7	1.4
Medication: Lisinopril	0.9	1.2	1.9	1.4	0.6
Medication: Co-codamol	0.8	0.9	1.2	1.1	0.8
High blood pressure	0.8	2.3	2.5	1.5	1.6
Weight	0.8	3.7	5.5	2.3	1.4
Mouth/teeth dental problems: Dentures	0.8	1.3	1.6	1.3	1.0
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	2.2	-0.6	-1.5
High blood pressure (siblings)	0.8	1.2	1.8	-1.3	-0.7
Number of full sisters	0.8	1.0	1.3	-0.8	-1.2
Medication: Aspirin	0.8	1.0	2.0	0.2	1.4
Hypertension (Self-reported)	0.8	2.1	2.7	1.2	1.6
Eye problems/disorders: Cataract	0.8	0.9	0.9	-1.0	-0.9
Osteoarthritis (self-reported)	0.8	1.0	2.0	-0.3	1.4
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.1	-1.0	-0.7
BMI	0.7	4.3	4.7	2.0	2.2
Vitamin and mineral supplements	0.7	1.0	1.5	-0.7	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	2.0	1.0	1.4
Diabetes (self-reported)	0.7	1.0	1.3	0.9	1.1
Arm fat percentage (right)	0.7	2.8	2.9	1.7	1.6
Eye problems/disorders: None of the above	0.7	0.8	1.0	-0.8	-1.0
Age at last live birth	0.7	0.9	1.4	-0.7	-1.2
Arm fat percentage (left)	0.7	2.9	3.2	1.8	1.6
Wears glasses or contact lenses	0.7	0.8	1.2	-0.7	1.1
Supplements: Fish oil (including cod liver oil)	0.7	0.9	0.9	0.9	1.0
Medication: Bendroflumethiazide	0.7	1.1	1.8	0.7	1.4
Myopia	0.7	1.1	1.4	1.2	0.8
Pain experienced in last month	0.7	1.2	1.8	-0.7	-1.4
Arm predicted mass (left)	0.7	3.4	5.2	2.3	1.3
HbA1C	0.6	0.7	0.9	0.7	0.9
Lung FVC	0.6	2.9	3.3	-1.6	-1.8
Hearing difficulty/problems: Yes	0.6	1.0	1.9	-0.0	1.4
Angina	0.6	0.7	1.4	0.2	1.2
Medication: Metformin	0.6	0.9	0.9	0.9	1.0
Trunk fat percentage	0.6	2.4	2.6	1.5	1.6
Age when periods started (menarche)	0.6	1.5	2.3	-1.5	-0.9
Medication: Levothyroxine sodium	0.6	1.0	1.4	-0.7	-1.2
Neuroticism score	0.6	1.2	1.6	-0.9	-1.3
Hip circumference	0.6	2.5	3.2	1.8	1.3
Impedance of arm (left)	0.6	2.8	3.3	-1.8	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	1.7	-1.3	-0.5
Peak expiratory flow (PEF)	0.6	1.5	2.6	-0.6	-1.6
Pulse wave reflection index	0.6	0.7	1.3	-1.1	-0.4
Headache pain in last month	0.6	1.0	1.6	0.6	1.3
Exposure to tobacco smoke outside home	0.6	0.8	1.1	1.1	0.7
Worry too long after embarrassment	0.6	1.0	1.2	-0.9	-1.1
Mean time to correctly identify matches	0.6	1.1	1.8	0.6	1.3
Diabetes diagnosed by doctor	0.6	1.1	1.5	0.8	1.2
Medication: Aspirin	0.6	0.8	1.5	0.2	1.2
Ever taken oral contraceptive pill	0.6	0.7	1.2	1.1	0.3
Age started oral contraceptive pill	0.6	0.8	1.6	-1.3	-0.0
Ever depressed for a whole week	0.6	0.8	1.1	-1.1	-0.7
Vascular/heart problems diagnosed by doctor	0.6	1.7	2.7	-0.9	-1.6
Bipolar Disorder (2018)	0.5	0.8	0.9	-0.9	-0.9
Ulcerative Colitis (UC)	0.5	0.9	1.8	-1.3	-0.3
Ovarian Cancer	0.5	0.7	0.9	-1.0	-0.7
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.4	-1.2	-0.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.2	-1.1	-0.2
Systolic blood pressure, automated reading	0.5	1.5	1.7	1.1	1.3
Supplements: Zinc	0.5	0.5	1.0	-0.1	1.0
Hand grip strength (right)	0.5	1.4	2.2	-0.8	-1.5
Townsend deprivation index at recruitment	0.5	0.7	1.2	1.1	0.5
Average weekly fortified wine intake	0.5	0.5	0.7	-0.8	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	0.9	-0.6	-1.0
Chronic bronchitis/emphysema (father)	0.5	0.5	0.9	0.5	0.9
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.2	0.0	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.9	1.3	0.7	1.1
Noisy workplace	0.5	0.6	1.2	0.3	1.1
Length of working week for main job	0.5	0.6	0.6	0.8	-0.7
Qualifications: College or University degree	0.5	1.5	2.7	-1.7	-0.4
Migraine (self-reported)	0.5	0.6	1.0	-0.5	1.0
Mood swings	0.5	0.9	1.6	-0.4	-1.3
Breast cancer (self-reported)	0.5	0.5	0.6	0.8	0.7
Commuting to job workplace: Public transport	0.5	0.6	0.8	0.9	0.7
Medication: Blood pressure	0.5	1.0	1.1	-0.9	-1.1
Arm fat-free mass (left)	0.5	2.5	4.2	2.1	0.8
Fractured/broken bones in last 5 years	0.5	0.6	1.0	-1.0	-0.4
Pack years of smoking	0.5	0.8	1.3	-0.5	1.1
Blood White Count	0.4	2.9	3.1	1.8	1.7
Tanning	0.4	4.6	7.8	2.8	1.2
Maternal smoking around birth	0.4	0.6	1.2	1.1	0.0
Impedance of arm (right)	0.4	1.8	2.2	-1.5	-1.2
Falls in the last year	0.4	0.5	1.0	-0.2	1.0
Number of live births	0.4	0.6	1.1	-1.1	-0.2
Happiness	0.4	0.5	0.7	-0.6	-0.8
Illnesses of mother	0.4	0.5	0.5	0.6	-0.7
Exposure to tobacco smoke at home	0.4	0.4	0.7	0.3	0.8
Breastfed as a baby	0.4	0.5	0.8	-0.9	-0.4
Blood clot in the leg (DVT)	0.4	0.5	1.0	-1.0	-0.2
Arm fat-free mass (right)	0.4	1.9	3.4	1.8	0.6
Medication: Omeprazole	0.4	0.5	0.8	-0.3	0.9
Heart disease (mother)	0.4	0.5	1.1	-0.1	1.0
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.9	-0.1	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	1.5	-0.5	-1.2
Commuting to job workplace: Walk	0.4	0.4	0.5	0.7	0.6
Medication: Gliclazide	0.4	0.5	0.6	-0.7	-0.7
Illnesses of father: High blood pressure	0.4	0.5	0.8	-0.9	0.5
Basal metabolic rate	0.4	2.0	3.7	1.9	0.5
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	0.8	-0.5	0.9
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.0	-1.0	-0.1
Alzheimer’s Disease (in father)	0.3	0.3	0.5	-0.2	-0.7
Breast Cancer	0.3	0.7	1.2	-1.1	-0.6
Bipolar Disorder (2011)	0.3	0.2	0.5	-0.1	-0.7
Mean Putamen Volume	0.3	0.4	0.8	0.9	0.2
Height	0.3	5.6	9.6	-1.3	-3.1
Smoking Status	0.3	0.8	1.2	-0.6	-1.1
Chronotype (morning person)	0.3	0.7	1.4	-0.3	1.2
Hand grip strength (left)	0.3	0.8	1.0	-0.8	-1.0
Sensitivity / hurt feelings	0.3	0.6	0.7	-0.8	-0.7
Pack years adult smoking proportion	0.3	0.4	0.5	-0.6	0.7
Fed-up feelings	0.3	0.5	0.8	-0.5	-0.9
Sitting height	0.3	2.1	4.0	-0.5	-2.0
Number of incorrect matches in round	0.3	0.5	0.7	0.6	-0.8
Hearing difficulty/problems with background noise	0.3	0.4	0.7	-0.8	0.4
Qualifications: None of the above	0.3	0.7	1.0	-1.0	-0.6
Medication: Simvastatin	0.3	0.4	0.7	-0.9	-0.3
Illnesses of siblings	0.3	0.4	0.6	0.8	0.5
Trunk fat-free mass	0.3	1.8	3.7	1.9	0.1
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.1	-0.5	-1.0
Medication: Cholesterol lowering	0.3	0.5	0.6	0.6	0.7
Trunk predicted mass	0.3	2.0	3.9	2.0	0.2
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.6	0.8	-0.2
Emphysema/chronic bronchitis	0.3	0.3	0.5	0.7	-0.4
Arm predicted mass (right)	0.3	1.4	2.8	1.7	0.3
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.7	0.8	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	0.7	-0.9	-0.4
Schizophrenia vs Biploar Disorder	0.2	0.3	0.3	-0.5	-0.5
Crohns Disease (2012)	0.2	0.3	0.6	-0.8	-0.0
Primary Biliary Cirrhosis	0.2	0.2	0.5	0.2	0.7
Blood Platelet Count	0.2	1.9	3.8	0.1	1.9
Heel T-Score	0.2	1.3	1.6	1.0	1.2
Hypothyroidism (self reported)	0.2	0.4	0.7	0.4	0.8
Type 2 Diabetes (T2D) (2018)	0.2	0.4	0.7	0.8	0.4
Relative age of first facial hair	0.2	0.5	0.8	0.4	-0.9
Leg fat-free mass (left)	0.2	1.0	1.8	1.4	0.3
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.5	0.7	0.1
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	-0.6	0.3
High blood pressure (mother)	0.2	0.2	0.3	0.4	0.6
Leg predicted mass (left)	0.2	0.9	1.8	1.3	0.2
Alcohol usually taken with meals	0.2	0.4	0.7	0.1	0.8
Mouth/teeth dental problems	0.2	0.3	0.4	-0.3	-0.7
Pain all over the body in last month	0.2	0.2	0.2	-0.5	-0.3
Medication: Ramipril	0.2	0.2	0.2	-0.4	-0.5
Alcohol intake versus 10 years previously	0.2	0.3	0.3	0.5	-0.5
Hair/balding pattern: Pattern 3	0.2	0.3	0.4	-0.4	-0.6
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.5	0.2	0.7
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	0.6	0.4	-0.7
Age at first live birth	0.2	0.3	0.4	-0.5	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.3	0.5	-0.4
Illnesses of father: Heart disease	0.2	0.2	0.4	-0.3	-0.6
Whole body fat-free mass	0.2	1.4	2.8	1.7	0.2
Ever had bowel cancer screening	0.2	0.3	0.5	-0.7	-0.3
Medication for cholesterol	0.2	0.2	0.3	-0.3	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.5	-0.5	-0.7
Whole body water mass	0.2	1.4	2.8	1.7	0.2
Hearing aid user	0.2	0.2	0.4	-0.2	0.6
Average weekly beer plus cider intake	0.2	0.3	0.4	-0.3	-0.7
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.5	-0.2	-0.7
Alcohol drinker status: Previous	0.2	0.3	0.5	-0.2	0.7
Impedance of whole body	0.2	1.2	1.7	-1.3	-0.8
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	-0.3	-0.4
Body Mass Index (BMI) (2010)	0.1	0.2	0.2	-0.5	0.4
Coronary Artery Disease (CAD)	0.1	0.1	0.2	-0.3	-0.4
Rheumatoid Arthritis	0.1	0.1	0.3	-0.1	-0.5
Blood Red Count	0.1	0.6	1.2	-1.1	-0.1
Systolic Blood Pressure	0.1	0.5	0.9	0.3	0.9
Current tobacco smoking	0.1	0.2	0.3	0.5	0.3
Relative age voice broke	0.1	0.1	0.2	0.3	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.5	0.3	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.2	-0.4	0.3
Depression (self-reported)	0.1	0.2	0.2	0.5	0.4
Standing height	0.1	1.2	2.2	0.4	-1.5
Tense / ‘highly strung’	0.1	0.1	0.3	0.5	-0.0
Loud music exposure frequency	0.1	0.1	0.1	-0.3	0.1
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.1	-0.1	-0.4
Comparative body size at age 10	0.1	0.2	0.2	0.5	-0.3
Number of children fathered	0.1	0.1	0.2	-0.5	-0.2
Neck or shoulder pain in last month	0.1	0.2	0.3	-0.5	0.3
Comparative height size at age 10	0.1	0.5	0.9	1.0	0.4
Family relationship satisfaction	0.1	0.2	0.3	-0.1	-0.6
Supplements: Vitamin C	0.1	0.1	0.1	0.2	0.4
Leg fat-free mass (right)	0.1	0.4	0.6	0.8	-0.3
Loneliness, isolation	0.1	0.2	0.2	0.2	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.2	0.5	0.1
Leg predicted mass (right)	0.1	0.4	0.7	0.9	-0.3
Average weekly champagne plus white wine intake	0.1	0.1	0.1	-0.0	-0.4
Risk taking	0.1	0.2	0.3	-0.6	-0.0
Prostate Cancer	0.0	0.1	0.1	0.2	0.3
Neuroticism (2016)	0.0	0.1	0.1	-0.3	0.2
Hair Pigment	0.0	1.3	2.2	-0.6	1.5
Impedance of leg (right)	0.0	0.2	0.3	0.4	0.5
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.0	0.2	0.1
Impedance of leg (left)	0.0	0.1	0.1	-0.3	-0.2
Financial difficulties in last 2 years	0.0	0.0	0.0	-0.1	-0.2
Hair/balding pattern: Pattern 4	0.0	0.1	0.1	-0.4	0.1
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.0	-0.1	-0.1
Medication: Amlodipine	0.0	0.1	0.1	0.1	0.3
Qualifications: nursing, teaching	0.0	0.1	0.1	-0.3	-0.3
Back pain experienced in last month	0.0	0.1	0.1	-0.2	0.3
Mineral and other dietary supplements	0.0	0.1	0.1	-0.3	-0.2
Illnesses of father: None of the above (group 1)	0.0	0.0	0.0	0.1	0.0
Smoking status: Current	0.0	0.0	0.1	0.3	-0.0
Financial situation satisfaction	0.0	0.0	0.1	0.2	0.1
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.1	-0.3	0.1
Irritability	0.0	0.1	0.1	0.4	-0.1
Unable to work because of sickness or disability	0.0	0.0	0.0	-0.2	0.1
Basal cell carcinoma (self-reported)	0.0	0.0	0.0	0.2	0.2

Hub : Genes

SLC9A2

Models

Trait associations