TWAS hub - ZNF592

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0990	0.0490	7.0e-03	0.039	NA	0.021	NA	0.053	3.6e-04	NA	7.4e-03	NA	3.6e-05
2	GTEx	Artery Aorta	0.1070	0.0460	1.1e-03	0.050	NA	0.023	NA	0.021	9.7e-04	NA	1.9e-02	NA	2.5e-02
3	GTEx	Cells Transformed fibroblasts	0.0970	0.0350	1.8e-04	0.055	NA	0.035	NA	0.036	6.0e-05	NA	1.1e-03	NA	9.5e-04
4	GTEx	Lung	0.1297	0.0687	3.1e-03	0.179	NA	0.187	NA	0.180	1.1e-13	NA	2.7e-14	NA	9.5e-14
5	GTEx	Muscle Skeletal	0.0757	0.0322	6.5e-04	0.057	NA	0.021	NA	0.054	2.7e-06	NA	3.2e-03	NA	5.4e-06
6	GTEx	Thyroid	0.2900	0.0800	5.0e-04	0.203	NA	0.166	NA	0.186	1.9e-15	NA	1.0e-12	NA	3.3e-14
7	METSIM	Adipose	0.0537	0.0204	4.5e-05	0.046	0.032	0.052	0.039	0.055	1.6e-07	1.1e-05	2.4e-08	1.6e-06	1.2e-08
8	TCGA	Breast Invasive Carcinoma	0.0187	0.0124	7.9e-03	0.007	0.007	0.008	NA	0.008	1.3e-02	9.9e-03	6.8e-03	NA	8.4e-03
9	TCGA	Head and Neck Squamous Cell Carcinoma	0.0224	0.0120	1.4e-03	0.026	0.020	0.019	NA	0.019	5.4e-04	2.5e-03	2.7e-03	NA	3.2e-03
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0978	0.0452	1.5e-04	0.037	0.037	0.041	NA	0.042	4.7e-05	4.6e-05	1.7e-05	NA	1.6e-05
11	TCGA	Stomach Adenocarcinoma	0.0490	0.0260	4.0e-04	0.056	0.044	0.020	NA	0.041	6.6e-05	3.9e-04	1.2e-02	NA	5.9e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Bipolar Disorder or Schizophrenia	4.4	10.7	50.4	2.0	7.1	1.7	2.6	1.7	1.5	1.2	-2.2	-4.2	1.7	-4.6
Impedance of leg (right)	3.8	18.2	49.4	-5.5	-4.7	-3.4	-7.0	-3.3	-5.6	-1.2	2.6	2.3	-5.1	2.4
Bipolar Disorder (2011)	3.7	3.6	12.6	1.8	3.5	2.8	1.3	2.7	0.0	2.5	-0.3	-0.3	0.0	-0.5
Impedance of leg (left)	3.4	16.6	43.8	-5.2	-4.6	-3.7	-6.6	-3.7	-4.9	-1.6	2.3	1.8	-4.9	2.0
Migraine (self-reported)	3.4	4.2	7.1	-2.2	0.9	-2.2	-2.0	-2.1	-1.4	-1.7	-1.8	-2.6	-2.2	-2.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.3	3.9	6.9	-2.4	0.3	-2.3	-2.1	-1.8	-1.6	-1.5	-1.4	-2.3	-2.6	-2.4
Schizophrenia (2018)	3.2	6.7	26.5	2.0	5.2	1.8	2.5	1.8	1.6	1.3	-2.2	-2.8	1.9	-3.1
Supplements: Fish oil (including cod liver oil)	3.2	4.2	7.6	2.7	-1.1	1.9	2.5	1.6	2.5	1.6	0.0	2.0	2.8	2.2
Commuting to job workplace: Walk	3.1	3.3	7.6	2.8	2.0	1.6	2.6	1.4	2.5	0.6	-0.4	-0.4	2.6	-0.3
Bipolar Disorder (2018)	2.8	4.5	24.3	0.6	4.9	0.6	1.0	0.5	0.5	0.2	-0.9	-3.2	0.0	-3.4
Forced expiratory volume in 1-second (FEV1), predicted	2.8	5.7	18.5	-1.0	-4.3	0.2	-2.3	0.1	-1.7	0.5	1.5	4.0	-0.5	4.1
Tinnitus: Yes, now most or all of the time	2.8	3.3	6.5	1.8	2.5	2.5	1.0	2.5	0.5	2.3	1.1	0.5	2.4	0.4
Impedance of whole body	2.8	14.1	35.2	-4.4	-4.9	-2.9	-5.9	-3.0	-4.4	-0.7	2.8	2.7	-4.1	2.8
Schizophrenia (2014)	2.7	5.9	24.8	1.9	5.0	1.7	2.3	1.7	1.5	1.3	-1.7	-2.6	1.8	-2.9
Pain all over the body in last month	2.7	2.9	6.7	-1.6	-0.7	-2.6	-0.6	-2.4	-0.3	-1.7	-1.1	-1.8	-2.4	-1.8
Worry too long after embarrassment	2.4	4.0	10.8	-1.7	-3.3	-1.3	-2.0	-1.4	-1.6	-1.0	2.6	2.1	-1.7	2.2
Eye problems/disorders: None of the above	2.4	2.8	6.2	-1.9	-1.9	-2.5	-1.7	-2.2	-0.8	-1.9	-0.5	-0.9	-2.0	-0.8
Alcohol drinker status: Never	2.4	2.9	5.6	-2.4	-0.0	-1.8	-2.2	-1.6	-1.8	-0.9	-0.7	-1.6	-2.3	-1.7
Unable to work because of sickness or disability	2.4	3.1	7.5	-0.9	0.9	-2.2	0.1	-2.2	0.4	-1.4	-1.2	-2.7	-1.9	-2.7
Multivitamins +/- minerals	2.3	3.0	6.2	1.9	2.3	2.5	1.8	2.0	1.0	1.6	-0.9	0.0	2.4	-0.1
Number of full sisters	2.2	2.7	11.2	1.0	3.3	1.6	0.8	1.4	0.1	2.3	-1.3	-1.3	1.2	-1.5
Rheumatoid Arthritis	2.1	2.9	9.8	-1.7	-1.6	-0.4	-2.0	-0.5	-2.1	-0.1	3.1	1.8	-1.1	1.7
Lung FVC	2.1	10.8	24.1	-2.3	-0.8	-4.3	-0.8	-4.2	0.3	-4.9	-3.4	-3.7	-3.7	-3.7
Frequency of depressed mood in last 2 weeks	2.1	3.0	7.8	1.8	-1.1	1.4	1.5	1.1	1.2	0.5	2.0	2.6	1.6	2.8
Hand grip strength (left)	2.0	5.3	13.5	-0.9	1.7	-2.3	-0.3	-2.4	0.4	-2.0	-3.2	-3.7	-1.6	-3.7
Forced expiratory volume in 1-second (FEV1)	2.0	6.6	22.1	-1.9	-4.7	-3.0	-2.1	-3.3	-0.4	-3.4	-0.3	1.2	-2.5	1.7
Standing height	2.0	19.7	71.5	-2.3	-8.5	-1.6	-3.7	-2.4	-2.3	-2.1	3.5	6.5	-1.8	7.0
Comparative height size at age 10	2.0	10.8	45.8	-2.0	-6.8	-1.9	-3.1	-2.2	-1.6	-2.3	1.4	4.1	-2.1	4.5
Diastolic blood pressure, automated reading	2.0	6.3	18.1	1.6	-2.4	1.8	0.9	2.1	0.8	0.9	3.4	4.0	2.1	4.3
Hypothyroidism (self reported)	1.8	4.2	11.8	0.9	-1.9	1.7	0.3	1.5	-0.1	1.7	2.8	3.4	1.5	3.4
Chronotype (morning person)	1.8	4.2	16.0	1.1	-2.7	0.3	0.9	0.1	1.2	0.3	4.0	2.9	0.7	3.1
Hearing difficulty/problems: Yes	1.8	2.8	8.8	-0.7	2.5	-1.5	-0.3	-1.8	0.1	-0.7	-0.2	-3.0	-1.0	-2.9
Other serious medical condition/disability diagnosed by doctor	1.8	2.3	4.2	-1.7	-0.3	-2.0	-1.5	-2.0	-0.8	-1.3	-1.0	-1.6	-2.0	-1.6
Falls in the last year	1.8	2.4	7.8	-1.8	-2.8	-1.6	-1.5	-1.4	-1.2	-1.3	-1.2	0.4	-1.9	0.4
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.0	7.7	2.0	0.6	-0.2	2.7	-0.6	2.8	-0.8	0.7	-0.8	0.9	-0.7
Breast cancer (self-reported)	1.8	2.2	5.9	0.6	0.1	2.0	0.4	2.4	-0.6	2.4	0.9	1.8	1.1	1.6
Medication: Blood pressure	1.8	3.4	7.9	2.8	-0.3	1.3	2.6	1.2	2.8	0.2	1.5	1.3	2.4	1.6
Impedance of arm (left)	1.7	7.8	17.8	-3.0	-4.2	-1.9	-4.2	-2.1	-3.0	-0.1	2.0	2.6	-2.7	2.6
Exposure to tobacco smoke at home	1.7	1.9	3.7	1.2	0.1	1.9	0.5	1.9	0.2	1.7	1.2	1.8	1.2	1.6
Medication: Gliclazide	1.7	1.9	4.9	-2.2	0.0	-1.3	-1.9	-1.0	-2.0	-0.5	-0.1	-1.0	-1.7	-1.1
Height	1.6	30.8	112.4	-1.0	-10.6	-1.1	-3.4	-2.4	-1.2	-1.8	5.1	9.0	-0.8	9.8
Trunk fat percentage	1.6	6.5	14.3	-2.0	-3.8	-2.2	-2.9	-2.5	-1.3	-2.5	3.0	2.3	-1.9	2.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.2	18.8	-1.8	-4.3	-2.4	-2.1	-2.6	-0.7	-2.9	-0.6	1.5	-2.0	1.9
Pulse wave Arterial Stiffness index	1.6	1.9	5.8	1.1	-1.2	1.5	0.3	1.4	0.2	0.8	0.9	2.4	1.1	2.4
Medication: Ibuprofen	1.6	2.0	4.8	-1.5	-0.9	-2.0	-1.4	-2.2	-0.6	-1.7	0.3	-0.7	-1.8	-0.7
Family relationship satisfaction	1.6	2.0	4.9	1.7	2.1	0.2	1.9	-0.2	2.2	0.6	-0.0	-1.5	1.4	-1.4
Leg pain on walking	1.6	2.0	7.0	-1.7	0.8	-0.0	-2.5	0.0	-2.7	0.7	-1.6	-0.5	-1.2	-0.7
Illnesses of father: High blood pressure	1.6	2.0	10.0	-0.7	-1.8	-0.9	-1.0	-0.8	-0.6	0.2	3.2	1.5	-0.9	1.5
Mean Putamen Volume	1.5	1.7	3.5	1.1	1.9	-0.4	1.6	-0.7	1.8	-1.1	-0.7	-1.8	0.1	-1.7
Ever used hormone-replacement therapy (HRT)	1.5	1.8	5.8	1.5	2.4	1.5	1.6	1.2	1.1	1.3	0.5	-0.5	1.5	-0.6
Hand grip strength (right)	1.5	4.2	8.6	-1.1	0.7	-2.3	-0.5	-2.6	0.2	-1.8	-2.9	-2.9	-1.8	-2.9
Fluid intelligence score	1.5	3.0	11.9	1.3	-1.5	0.8	0.7	0.6	0.8	1.0	3.4	2.5	1.0	2.7
Mineral and other dietary supplements	1.5	2.0	3.7	-1.9	1.0	-1.3	-1.6	-1.0	-1.7	-0.8	0.4	-1.5	-1.9	-1.6
Irritability	1.5	2.5	6.0	0.8	-1.2	1.8	0.1	1.7	-0.4	2.1	1.3	2.4	1.3	2.4
Lung FEV1/FVC ratio	1.4	7.3	19.1	-1.3	-4.1	-0.8	-2.6	-0.8	-1.6	-1.0	3.6	4.1	-1.2	4.4
Vitamin and mineral supplements	1.4	2.0	3.6	-1.5	-1.8	-1.9	-1.6	-1.6	-0.9	-1.3	1.1	0.2	-1.8	0.3
Severe depression (siblings)	1.4	1.5	4.2	2.0	1.6	0.8	1.5	0.5	2.0	-0.1	0.5	-0.4	1.6	-0.3
Trunk fat mass	1.4	6.1	15.4	-1.5	-3.9	-1.9	-2.3	-2.3	-0.9	-2.6	3.0	2.6	-1.5	3.1
Had menopause	1.4	1.8	11.3	-0.2	3.4	0.7	-0.1	0.6	-0.8	0.6	-0.4	-1.6	0.1	-1.9
Impedance of arm (right)	1.4	6.5	14.7	-2.6	-3.8	-1.4	-3.8	-1.6	-2.8	0.3	2.0	2.6	-2.4	2.6
Breastfed as a baby	1.4	1.8	3.6	-1.6	1.5	-0.9	-1.4	-0.9	-1.5	-0.6	0.4	-1.7	-1.5	-1.9
Age started oral contraceptive pill	1.4	1.8	5.6	1.4	2.4	0.9	1.7	0.9	1.4	0.3	0.5	-1.2	1.2	-1.3
Depressed Affect (Nagel 2018)	1.3	2.8	5.4	-2.3	-1.9	-1.6	-1.8	-1.8	-2.0	-1.2	1.0	0.4	-2.3	0.4
Irritable Bowel Disease (IBD)	1.3	3.0	8.1	-1.3	1.2	-1.8	-0.2	-2.0	-0.4	-0.9	-1.6	-2.6	-2.0	-2.8
Supplements: Zinc	1.3	1.4	3.7	1.7	0.1	1.0	1.9	0.7	1.7	0.8	-0.6	0.6	1.5	0.7
Diabetes (father)	1.3	1.6	4.9	-0.7	-2.1	-1.8	0.0	-1.8	0.6	-2.2	1.0	0.1	-0.8	0.4
Medication: Atenolol	1.3	1.6	4.4	0.8	1.1	1.5	0.4	2.1	-0.2	1.9	1.6	0.9	1.0	1.0
Sitting height	1.3	9.5	28.0	-0.8	-5.3	-0.6	-1.7	-1.0	-1.1	-1.0	4.3	4.9	-0.9	5.2
Chronic bronchitis/emphysema (father)	1.3	1.5	5.5	0.1	2.3	2.0	-0.2	1.9	-1.3	1.2	-0.0	0.0	0.8	-0.2
Time employed in main current job	1.3	1.5	5.5	-1.7	0.6	-0.1	-2.1	0.3	-2.3	0.8	0.8	-0.1	-1.2	-0.4
Medication: Cholesterol lowering	1.3	2.1	5.6	-2.2	0.4	-1.2	-2.4	-0.9	-2.2	-0.1	0.5	-0.7	-1.9	-0.9
Eye problems/disorders: Cataract	1.3	1.5	2.9	1.3	0.1	1.7	0.9	1.4	0.6	1.2	0.5	1.4	1.6	1.5
Commuting to job workplace: Public transport	1.3	1.5	6.6	1.6	0.6	-0.5	2.0	-0.6	2.6	-0.7	0.8	-0.8	0.8	-0.6
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	5.1	-0.6	1.1	-1.1	0.0	-1.5	-0.0	-0.9	-1.5	-2.2	-1.1	-2.3
Medication for hormone replacement therapy	1.2	1.4	3.0	-1.1	0.9	-1.4	-0.5	-1.3	-0.3	-0.9	-0.9	-1.7	-1.3	-1.7
Medication: Co-codamol	1.2	1.4	4.0	-0.7	-2.0	-0.3	-1.2	-0.3	-0.7	-0.5	1.5	1.7	-0.6	1.7
Fed-up feelings	1.2	2.2	8.0	-0.3	-2.8	-0.3	-0.6	-0.4	-0.3	-0.5	1.6	2.4	-0.3	2.6
Forced vital capacity (FVC)	1.2	4.5	12.6	-1.6	-3.5	-2.6	-1.4	-3.0	-0.2	-3.1	-1.2	0.4	-2.2	0.7
Mouth/teeth dental problems: Dentures	1.2	2.0	4.6	1.8	1.6	1.3	2.1	1.2	1.7	1.0	-1.2	-0.5	1.7	-0.5
Illnesses of mother	1.2	1.5	2.8	1.3	-1.5	0.9	1.3	0.8	1.2	0.8	0.3	1.6	1.2	1.7
Ever highly irritable/argumentative for 2 days	1.2	1.4	3.5	1.0	-0.3	1.2	0.5	1.1	0.3	1.5	1.9	1.6	0.9	1.5
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	6.8	0.3	-1.7	1.4	-0.2	1.1	-0.6	1.5	1.4	2.6	1.0	2.6
Body fat percentage	1.2	4.7	8.0	-1.9	-2.8	-2.3	-2.5	-2.5	-1.1	-2.6	2.4	1.4	-2.0	1.8
Comparative body size at age 10	1.2	3.2	7.0	-1.4	0.4	-1.9	-0.3	-1.8	-0.2	-2.7	-1.6	-2.5	-2.0	-2.5
Number of full brothers	1.2	1.5	2.9	-1.7	0.1	-1.4	-1.2	-1.0	-1.2	-1.1	-0.9	-1.3	-1.6	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	4.1	1.3	1.5	0.5	2.0	-0.0	1.6	0.6	-1.4	-1.3	1.0	-1.4
Emphysema/chronic bronchitis	1.2	1.4	5.0	1.0	2.2	1.0	1.1	0.8	0.7	1.0	-1.0	-1.1	1.1	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.5	4.0	-1.3	-1.2	-2.0	-0.6	-1.7	-0.1	-1.3	-0.2	-1.0	-1.5	-1.0
Crohns Disease (2017)	1.1	2.5	6.9	-0.1	1.4	-1.3	1.0	-1.6	1.0	-0.9	-2.1	-2.6	-0.6	-2.6
Ulcerative Colitis (UC)	1.1	2.0	5.4	-1.6	0.2	-1.7	-0.9	-1.7	-1.0	-0.9	-0.3	-1.5	-2.3	-1.7
Average weekly spirits intake	1.1	1.3	4.8	1.9	-0.1	0.4	1.9	0.2	2.2	-0.5	0.7	0.4	1.0	0.5
Pack years adult smoking proportion	1.1	1.7	4.1	0.4	-0.4	1.7	-0.3	1.6	-0.6	1.4	0.9	2.0	1.1	1.9
Hair/balding pattern: Pattern 3	1.1	1.7	4.7	0.8	1.7	1.8	0.7	2.0	-0.3	2.2	-1.1	-0.2	0.9	-0.4
Number of live births	1.1	1.5	5.9	0.7	2.4	0.5	1.3	0.3	0.7	0.2	-1.1	-1.7	0.5	-1.8
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	2.9	-1.2	-1.3	-1.7	-1.3	-1.7	-0.3	-1.5	0.3	-0.2	-1.4	-0.1
Birth weight of first child	1.1	2.0	3.6	-1.6	-0.2	-1.8	-1.7	-1.8	-0.7	-1.9	-0.2	-1.2	-1.8	-1.1
Peak expiratory flow (PEF)	1.1	2.5	9.6	-1.1	-3.1	-2.2	-0.9	-2.2	0.1	-1.8	-0.5	0.4	-1.5	0.6
Glaucoma (self-reported)	1.1	1.3	2.8	1.0	0.8	1.3	0.6	1.3	0.4	1.3	1.7	1.0	1.3	1.1
Health satisfaction	1.1	1.4	3.3	-1.7	0.2	-1.1	-1.7	-0.9	-1.7	-0.7	-0.1	-0.7	-1.8	-0.7
Shortness of breath walking on level ground	1.1	1.3	3.0	-1.3	-0.5	-1.2	-1.0	-1.2	-0.9	-0.9	-1.7	-0.9	-1.4	-0.9
Pulse rate, automated reading	1.1	3.4	15.9	-1.2	4.0	1.1	-1.5	1.5	-2.3	1.0	-1.1	-1.6	-0.5	-2.0
Neuroticism (Nagel 2018)	1.0	2.3	4.5	-1.8	-2.1	-1.5	-1.7	-1.5	-1.5	-0.9	1.4	0.7	-2.1	0.7
Fasting Glucose	1.0	1.2	4.0	1.4	-0.8	0.2	1.7	0.1	2.0	-0.2	0.3	0.7	1.3	0.9
Blood Platelet Count	1.0	11.3	37.3	-1.8	4.1	-2.5	0.3	-2.5	-0.1	-1.6	-3.6	-5.9	-2.1	-6.1
Systolic blood pressure, automated reading	1.0	3.0	6.8	2.4	0.8	1.8	2.2	1.8	2.0	1.1	0.7	1.1	2.6	1.3
Diabetes (mother)	1.0	1.3	3.8	0.7	-0.7	-1.4	1.5	-1.5	1.9	-1.2	-0.6	-0.8	-0.1	-0.6
Hearing difficulty/problems with background noise	1.0	1.7	8.5	1.1	2.9	0.4	1.1	-0.0	0.9	0.8	0.2	-1.6	0.7	-1.6
Mouth/teeth dental problems	1.0	1.5	5.5	-1.8	-0.1	-0.4	-2.1	-0.4	-2.4	0.3	0.2	-0.1	-1.4	-0.4
Qualifications: O levels/GCSEs or equivalent	1.0	1.5	4.5	0.3	-1.9	0.7	-0.2	1.0	-0.1	1.1	1.1	2.1	0.6	2.1
Medication: Ventolin 100micrograms inhaler	1.0	1.3	5.1	0.3	2.2	0.4	0.1	0.4	0.2	-0.2	-1.5	-1.7	0.6	-1.8
Pulse wave peak to peak time	1.0	1.2	2.8	-1.1	0.6	-1.4	-0.5	-1.3	-0.3	-0.7	-0.4	-1.6	-1.0	-1.7
Whole body fat mass	1.0	4.2	9.3	-1.3	-3.1	-1.6	-1.9	-1.9	-0.8	-2.3	2.6	2.1	-1.2	2.6
Guilty feelings	1.0	1.4	4.1	-0.5	-2.0	-1.4	-0.3	-1.8	0.2	-1.6	1.2	0.5	-1.1	0.7
Pack years of smoking	1.0	1.4	3.5	0.4	-0.3	1.6	-0.2	1.4	-0.5	1.3	1.1	1.9	1.1	1.8
Blood Eosinophil Count	0.9	6.9	23.3	-0.7	4.8	-1.6	0.5	-2.2	0.5	-1.0	1.1	-4.5	-0.9	-4.6
Age when periods started (menarche)	0.9	2.2	9.2	0.1	3.0	-0.3	1.0	-0.8	0.4	0.5	-0.5	-2.5	0.0	-2.5
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	4.9	-1.0	0.6	1.4	-1.2	1.6	-2.2	1.6	2.1	1.5	0.0	1.3
Hip circumference	0.9	4.0	8.4	-1.6	-2.6	-1.9	-2.1	-2.1	-1.0	-2.9	2.2	1.4	-1.6	1.9
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	4.9	-1.3	-0.6	0.4	-2.0	0.7	-2.2	1.0	0.4	1.3	-0.7	1.2
Pulse rate	0.9	1.6	3.6	-0.5	1.6	1.6	-1.5	1.8	-1.9	1.3	0.8	0.7	-0.0	0.4
Blood clot in the leg (DVT)	0.9	1.2	4.1	-0.4	1.2	-0.8	0.1	-1.2	0.0	-0.5	-1.0	-1.9	-0.8	-2.0
Birth weight	0.9	2.0	5.7	0.7	2.4	2.1	0.4	1.8	-0.1	2.0	-1.0	-0.2	1.6	-0.4
Forced vital capacity (FVC), Best measure	0.9	3.4	11.4	-1.3	-3.4	-2.0	-1.3	-2.4	-0.2	-2.5	-1.4	0.8	-1.7	1.0
Leg fat percentage (right)	0.9	3.1	6.1	-1.9	-1.3	-2.1	-2.2	-2.1	-1.3	-2.5	1.7	0.3	-2.0	0.7
Wheeze or whistling in the chest in last year	0.9	1.6	4.4	-1.3	2.1	-0.0	-1.4	-0.0	-1.7	0.2	-1.1	-1.4	-0.6	-1.6
Average weekly red wine intake	0.9	1.3	4.2	1.5	-0.2	0.2	1.7	-0.3	2.1	-0.3	1.6	0.5	1.1	0.6
Ever taken oral contraceptive pill	0.9	1.0	3.5	0.7	0.0	0.7	0.4	0.7	0.4	1.4	1.9	1.2	0.9	1.2
Eye problems/disorders: Glaucoma	0.9	1.0	2.8	0.5	1.1	1.4	0.1	1.3	-0.3	1.1	1.7	0.9	0.8	0.8
Myopia	0.9	1.3	3.5	1.6	0.8	0.4	1.6	-0.0	1.9	-0.3	1.4	0.0	1.6	0.2
Cholesterol lowering medication	0.9	1.3	2.4	1.5	1.0	1.5	1.5	1.4	1.0	1.0	0.5	0.6	1.5	0.5
Heart disease (siblings)	0.9	1.1	4.4	-0.9	-0.6	-1.1	-0.2	-0.8	-0.2	-1.1	-2.1	-1.1	-1.1	-1.1
Alzheimer’s Disease (in mother)	0.8	0.9	3.5	-0.9	0.5	0.9	-1.1	1.1	-1.9	1.5	-0.2	0.4	-0.2	0.1
HDL Cholesterol	0.8	1.3	3.2	-1.2	0.7	-1.3	-0.8	-1.1	-0.7	-0.2	-0.8	-1.7	-1.3	-1.8
Lupus	0.8	1.2	2.8	-0.4	1.0	-1.2	0.0	-1.3	0.1	-1.0	-0.9	-1.7	-1.1	-1.7
Cardiovascular Disease	0.8	2.6	8.5	1.1	-2.2	0.5	0.3	0.7	0.9	-0.1	2.1	2.6	1.1	2.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	3.1	0.1	-0.6	0.8	-0.3	0.8	-0.5	0.8	1.6	1.7	0.3	1.8
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.9	5.2	-0.3	1.0	1.6	-0.6	1.9	-1.4	1.4	2.3	1.4	0.6	1.3
Medication: Levothyroxine sodium	0.8	1.3	3.4	-0.4	-1.4	0.7	-0.8	0.7	-1.0	1.0	1.3	1.9	0.4	1.8
Financial difficulties in last 2 years	0.8	1.1	2.6	1.1	0.6	1.6	0.8	1.4	0.2	1.4	0.2	1.0	1.1	0.9
Pulse wave reflection index	0.8	1.0	2.6	0.9	-1.4	0.3	0.7	0.3	0.7	-0.4	1.4	1.4	0.6	1.6
Gout (self-reported)	0.8	1.1	3.8	-1.0	-2.0	-0.6	-1.4	-0.4	-0.9	-0.5	-0.1	1.1	-0.7	1.2
Exposure to tobacco smoke outside home	0.8	1.0	1.9	0.9	-0.6	1.3	0.7	1.4	0.3	1.1	0.3	1.4	1.0	1.3
Medication for pain relief, constipation, heartburn	0.8	1.4	4.3	1.0	2.1	1.5	1.1	1.3	0.2	1.7	0.1	-0.4	1.3	-0.5
Medication: Allopurinol	0.8	1.0	2.5	-1.4	-1.3	-0.7	-1.6	-0.4	-1.4	-0.5	-1.0	0.5	-0.8	0.4
Mean time to correctly identify matches	0.8	1.5	5.1	1.0	2.2	0.6	1.4	0.3	1.0	0.1	-1.2	-1.6	0.6	-1.6
Alcohol intake frequency.	0.8	1.8	5.4	-1.2	2.3	0.2	-1.5	0.2	-1.7	0.7	-1.6	-1.4	-0.6	-1.6
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	2.1	0.9	1.3	1.5	1.1	1.3	0.2	1.0	-0.5	-0.0	1.3	-0.1
Illnesses of siblings: Diabetes	0.8	1.0	2.6	-0.1	-1.6	-1.4	0.7	-1.5	1.0	-1.3	-0.7	-0.5	-0.6	-0.4
Pain type(s) experienced in last month: Hip pain	0.8	0.9	2.5	1.1	-1.4	0.4	0.8	0.3	1.1	-0.3	0.3	1.3	1.0	1.6
Medication: Atorvastatin	0.8	1.0	3.3	-0.2	1.4	-0.6	0.3	-0.5	0.2	-0.4	-1.1	-1.7	-0.8	-1.8
Leg fat percentage (left)	0.8	2.9	7.5	-1.6	-1.2	-2.3	-1.8	-2.4	-0.8	-2.7	1.4	-0.1	-1.9	0.3
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.3	-1.4	-1.1	-1.1	-1.5	-0.5	-1.0	-1.2	-0.6	-0.1	-1.2	-0.1
Basal cell carcinoma (self-reported)	0.8	1.0	1.9	-1.0	0.4	-1.0	-1.1	-1.1	-0.7	0.1	-1.3	-1.3	-0.8	-1.4
Heel T-Score	0.7	5.8	19.5	1.7	4.4	3.2	2.0	2.9	0.6	2.5	1.9	-0.1	2.9	-0.3
Respiratory disease	0.7	1.5	4.5	-0.6	1.7	-0.1	-0.2	0.0	-0.6	0.3	-2.0	-1.9	-0.4	-2.1
Medication: Metformin	0.7	1.0	2.4	-1.5	-0.9	-0.7	-1.5	-0.7	-1.5	-0.5	-0.7	0.1	-1.3	0.0
Alcohol usually taken with meals	0.7	1.1	2.0	1.2	1.0	1.2	1.4	1.2	0.9	1.3	0.7	0.4	1.3	0.3
Allergy	0.7	1.5	4.2	-0.3	-1.9	-0.3	-0.5	-0.2	-0.1	-0.9	2.0	1.9	-0.4	2.0
Weight	0.7	3.6	11.2	-0.5	-3.3	-1.2	-0.9	-1.6	0.1	-2.6	1.9	2.3	-0.5	2.8
Depression (self-reported)	0.7	0.8	2.4	1.0	0.9	1.0	0.9	0.6	0.5	1.5	1.0	0.6	0.8	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	4.6	0.9	2.1	1.0	1.1	0.4	0.4	1.6	0.3	-0.8	0.8	-0.8
Chronic bronchitis/emphysema (mother)	0.7	0.8	2.1	-0.7	1.5	-0.0	-1.3	0.0	-1.0	1.1	0.4	-0.9	-0.5	-1.2
Age at first live birth	0.7	1.3	4.3	-0.4	-1.4	-0.0	-0.7	0.0	-0.8	1.3	2.1	1.5	-0.2	1.5
Medication: Seretide 50 evohaler	0.7	0.8	2.0	0.8	1.2	0.0	1.2	-0.1	1.4	-0.4	-0.7	-1.2	0.7	-1.1
Leg fat mass (right)	0.7	2.9	5.2	-1.3	-2.1	-1.6	-1.7	-1.7	-0.9	-2.3	2.2	1.4	-1.3	1.7
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	3.1	-0.6	0.8	0.0	-0.2	0.2	-0.8	0.4	-1.8	-1.0	-0.6	-1.3
Qualifications: nursing, teaching	0.7	1.1	2.0	-1.4	-1.2	-0.9	-1.3	-1.0	-1.2	-1.3	-0.3	0.1	-1.1	0.1
Medication for cholesterol	0.7	1.1	3.0	-1.6	-0.7	-0.8	-1.7	-0.5	-1.6	-0.1	-0.6	-0.1	-1.4	-0.3
Asthma (self-reported)	0.7	1.5	4.5	-0.9	1.3	-0.6	-0.4	-0.5	-0.6	-0.3	-2.0	-2.0	-0.5	-2.1
Osteoarthritis (self-reported)	0.7	0.9	2.3	-0.5	-1.3	-1.4	0.1	-1.5	0.4	-1.4	-0.9	-0.5	-0.7	-0.2
Average weekly champagne plus white wine intake	0.7	1.0	2.4	0.8	-1.6	-0.1	0.6	0.0	1.1	-0.2	1.4	1.3	0.4	1.4
Wears glasses or contact lenses	0.7	0.8	2.0	1.0	0.2	1.0	0.9	0.6	0.5	0.9	1.4	1.1	0.9	1.1
Leg fat mass (left)	0.7	2.7	5.9	-1.2	-2.0	-1.7	-1.6	-1.9	-0.6	-2.4	1.9	1.1	-1.3	1.5
Major Depression (MDD)	0.6	0.8	4.6	0.0	2.2	0.3	0.2	-0.0	-0.1	0.4	-0.2	-1.3	0.2	-1.4
Age at First Birth	0.6	0.9	2.0	-1.3	0.1	-0.6	-1.4	-0.7	-1.4	-0.4	-0.0	-0.8	-1.2	-1.0
HbA1C	0.6	0.7	1.3	0.8	-1.0	0.0	0.8	-0.3	1.0	-0.5	1.1	0.9	0.5	1.1
Blood White Count	0.6	4.5	9.4	-2.0	2.4	-2.0	-1.3	-2.0	-1.0	-2.3	-1.4	-3.1	-1.7	-3.1
Systolic Blood Pressure	0.6	3.1	6.0	2.3	-1.3	0.8	1.8	0.8	2.4	0.2	1.5	2.0	2.2	2.3
Allergy or Eczema	0.6	1.5	7.4	0.0	2.7	0.9	-0.0	1.1	-0.6	1.5	-0.4	-1.3	0.4	-1.5
Relative age of first facial hair	0.6	1.2	4.9	-0.0	-2.2	0.1	0.2	-0.2	0.1	-1.1	-0.1	1.8	-0.0	1.9
Townsend deprivation index at recruitment	0.6	0.9	1.5	1.1	-0.8	0.7	1.1	0.8	1.0	0.8	0.4	1.1	1.0	1.2
Supplements: Glucosamine	0.6	0.8	4.4	0.1	-2.1	-0.8	0.2	-1.1	0.7	-1.2	-0.6	0.5	-0.1	0.7
Number of incorrect matches in round	0.6	1.0	4.2	0.3	2.0	0.5	0.5	0.3	0.3	1.2	-0.7	-1.3	0.1	-1.4
Hair/balding pattern: Pattern 2	0.6	0.7	1.6	-1.0	-0.5	-1.0	-0.5	-0.9	-0.5	-1.2	0.1	-0.7	-1.3	-0.8
Medication: Simvastatin	0.6	0.9	2.4	0.3	1.0	1.1	-0.3	1.0	-0.4	1.5	1.5	0.8	0.8	0.8
Worrier / anxious feelings	0.6	1.1	3.3	-0.4	-1.2	-1.6	-0.1	-1.8	0.4	-1.3	1.3	-0.1	-1.1	0.1
Asthma	0.6	1.2	4.2	-0.5	1.2	-0.3	-0.1	-0.3	-0.3	-0.2	-2.1	-1.8	-0.2	-1.9
Medication: Lansoprazole	0.6	0.6	1.3	-0.9	-0.4	-1.1	-0.5	-1.2	-0.4	-1.0	0.3	-0.6	-1.1	-0.6
Loud music exposure frequency	0.6	0.6	1.6	0.4	0.2	-0.6	1.2	-0.6	1.3	-0.8	-0.7	-1.0	0.1	-0.9
Headache pain in last month	0.6	1.0	2.3	-1.4	0.1	-0.7	-1.5	-0.4	-1.5	-0.6	-1.2	-0.7	-1.0	-0.7
Number of children fathered	0.6	0.7	3.3	0.3	1.8	0.6	0.6	0.4	-0.1	0.7	-0.5	-1.0	0.2	-1.2
Medication: Omeprazole	0.6	0.8	2.5	-1.3	-0.0	-0.9	-1.6	-0.4	-1.2	-0.6	-0.2	-0.4	-1.1	-0.5
Age at last live birth	0.6	0.8	2.1	-1.1	0.9	-0.5	-1.3	-0.2	-1.4	0.5	1.4	-0.3	-0.8	-0.4
Commuting to job workplace: Car/motor vehicle	0.6	0.6	3.2	-0.8	-1.8	-0.5	-0.5	-0.6	-0.4	-0.5	-1.0	0.3	-0.6	0.4
Medication: Aspirin	0.6	0.8	4.2	-0.7	0.1	-0.4	-0.9	-0.1	-0.6	-0.1	-2.1	-0.9	-0.8	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.2	-1.1	0.6	-0.7	-0.9	-0.5	-0.9	-1.0	-0.2	-0.8	-1.0	-0.9
Back pain experienced in last month	0.6	0.9	2.6	0.2	-1.3	-1.2	0.7	-1.6	1.2	-1.3	0.6	0.0	-0.5	0.2
Medication: Paracetamol	0.6	0.9	1.8	-1.1	-1.1	-0.7	-1.4	-0.9	-1.2	-0.1	0.6	0.6	-1.2	0.5
Ever depressed for a whole week	0.6	0.7	3.6	0.4	1.9	0.4	0.2	0.3	0.1	0.9	0.1	-1.1	0.4	-1.2
Pain experienced in last month	0.6	1.0	2.8	0.7	-0.1	1.5	0.1	1.7	-0.3	1.6	0.4	1.0	0.8	0.9
Alcohol drinker status: Previous	0.6	0.7	1.3	-0.9	1.0	-0.3	-1.0	-0.5	-0.7	-0.2	-1.1	-1.1	-0.5	-1.1
Alzheimer’s Disease (including proxy)	0.5	0.7	2.2	-0.6	1.3	0.9	-0.5	1.1	-1.5	1.3	-0.1	0.1	-0.1	-0.2
Triglycerides	0.5	0.8	1.7	0.5	0.4	1.3	-0.3	1.3	-0.4	1.0	1.1	1.1	0.6	1.1
Blood Red Count	0.5	4.4	11.0	-1.1	-2.5	0.8	-2.3	0.6	-2.4	1.2	2.6	3.3	-0.4	3.1
Neuroticism	0.5	1.2	3.2	-1.1	-1.8	-1.0	-1.0	-1.1	-0.9	-0.7	1.2	0.7	-1.3	0.8
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.3	-0.8	-0.4	-0.8	-0.7	-0.7	-0.5	-0.8	-0.8	-0.5	-1.2	-0.5
Leg fat-free mass (left)	0.5	2.4	7.7	1.2	-2.0	0.8	1.1	0.4	1.1	-0.8	1.1	2.5	1.4	2.8
Relative age voice broke	0.5	0.7	1.7	-1.1	0.0	-0.8	-1.2	-0.6	-1.0	-1.0	-0.4	-0.4	-1.3	-0.3
High blood pressure (mother)	0.5	0.7	1.5	-0.5	-0.1	-1.2	-0.3	-1.2	0.1	-1.2	0.9	-0.7	-0.9	-0.6
Waist circumference	0.5	1.9	4.0	-0.6	-2.0	-1.2	-1.2	-1.5	-0.1	-2.0	1.7	1.3	-0.5	1.7
Illnesses of siblings	0.5	0.7	1.4	0.6	0.2	1.1	0.3	0.8	-0.0	0.9	1.1	1.2	0.8	1.1
Noisy workplace	0.5	0.6	2.7	-0.0	1.6	0.3	-0.5	0.4	-0.3	1.2	-0.6	-0.9	0.2	-1.0
Tense / ‘highly strung’	0.5	0.9	2.2	0.9	1.5	0.6	1.1	0.5	0.7	0.5	-1.0	-1.0	0.9	-1.1
Hair/balding pattern: Pattern 4	0.5	1.2	3.7	0.1	-0.2	-1.6	0.5	-1.9	1.2	-1.9	1.0	-0.8	-0.5	-0.6
Medication: Paracetamol	0.5	0.9	1.6	-1.0	-1.2	-0.7	-1.2	-0.6	-1.1	-0.4	0.9	0.9	-1.1	0.8
Neck or shoulder pain in last month	0.5	0.7	2.5	-0.3	1.6	-0.4	-0.1	-0.6	-0.2	-0.6	-0.7	-1.3	-0.5	-1.3
Chest pain or discomfort	0.5	0.8	2.2	-0.7	1.0	0.8	-1.1	0.8	-1.5	1.2	-0.8	-0.1	0.1	-0.3
Illnesses of father: Heart disease	0.5	0.7	1.3	-0.9	-0.4	-1.2	-0.8	-1.1	-0.6	-0.6	-0.7	-0.7	-1.1	-0.8
Leg fat-free mass (right)	0.5	2.7	6.0	1.8	-1.7	0.9	1.8	0.4	1.9	-0.8	0.7	2.2	1.8	2.5
Leg predicted mass (right)	0.5	2.6	6.0	1.8	-1.6	0.9	1.8	0.4	1.9	-0.8	0.7	2.2	1.8	2.4
Miserableness	0.5	0.9	3.2	-1.4	-0.2	-0.4	-1.4	-0.6	-1.8	0.6	0.6	0.2	-1.3	0.2
Average weekly beer plus cider intake	0.5	0.7	2.0	-0.1	-1.4	0.1	-0.3	0.2	-0.4	1.0	0.8	1.4	0.1	1.3
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.7	-0.6	-1.2	-0.5	-0.8	-0.4	-0.6	-0.7	1.6	0.9	-1.0	1.0
Ovarian Cancer	0.4	0.5	2.3	-1.1	-0.0	-0.1	-1.2	0.2	-1.5	0.1	0.2	0.2	-0.9	0.0
LDL Cholesterol	0.4	0.6	2.3	-0.2	1.5	-0.3	0.3	-0.4	0.2	-0.1	0.7	-1.3	-0.2	-1.3
Neuroticism (2016)	0.4	0.6	1.6	0.2	0.6	1.0	-0.5	1.1	-0.5	1.0	1.3	0.7	0.0	0.6
Primary Biliary Cirrhosis	0.4	0.5	1.7	0.2	-0.1	0.8	0.1	0.8	-0.3	0.7	1.3	1.1	0.4	0.9
Type 2 Diabetes (T2D) (2012)	0.4	0.5	2.8	-0.8	-0.4	-0.5	-0.7	-0.7	-0.7	-0.2	1.7	0.3	0.0	0.3
BMI	0.4	2.1	7.8	-1.1	-2.0	-1.8	-1.0	-1.6	-0.1	-2.8	1.3	0.5	-1.3	0.7
Average weekly fortified wine intake	0.4	0.5	1.3	0.5	-0.9	0.7	0.6	0.8	0.1	0.5	0.3	1.1	0.4	1.1
High blood pressure	0.4	1.1	3.8	-0.0	-1.0	0.4	-0.8	0.7	-0.5	0.1	1.4	1.8	0.4	1.9
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	1.7	-0.8	-1.3	-0.7	-0.4	-0.4	-0.5	-0.8	-0.1	0.3	-0.8	0.4
Leg predicted mass (left)	0.4	2.4	7.5	1.2	-1.9	0.8	1.1	0.4	1.2	-0.8	1.1	2.5	1.4	2.7
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.8	1.0	0.7	0.6	1.4	0.3	0.9	0.9	-0.4	0.1	1.0	0.1
Medication: Ramipril	0.4	0.5	1.7	0.8	0.2	-0.4	0.6	-0.5	1.3	-1.3	0.4	-0.3	0.3	-0.1
Neuroticism score	0.4	0.8	1.6	-0.8	-1.2	-0.7	-0.7	-1.0	-0.9	-0.4	1.3	0.7	-1.1	0.7
Alcohol intake versus 10 years previously	0.4	0.6	1.5	-1.2	-0.9	-0.7	-1.2	-0.6	-1.0	-0.6	-0.0	0.3	-0.9	0.3
Father’s age at death	0.4	0.5	1.8	0.4	0.8	0.1	0.4	0.0	0.5	0.0	-1.3	-1.0	0.4	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.1	-0.4	-0.5	-1.1	-0.6	-1.1	0.3	-0.8	-0.2	-0.5	-0.4	-0.4
Arm fat mass (right)	0.4	1.5	3.6	-0.2	-1.7	-0.9	-0.4	-1.1	0.3	-1.9	1.8	1.3	-0.2	1.7
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.6	-0.0	-1.6	-0.9	0.1	-0.6	0.6	-0.8	0.0	0.4	-0.5	0.5
Qualifications: College or University degree	0.4	1.4	3.7	-1.5	-0.8	-1.2	-1.4	-1.1	-1.1	-1.9	-0.4	-0.5	-1.5	-0.5
Mouth/teeth dental problems: Loose teeth	0.4	0.4	2.1	0.0	1.4	0.6	-0.3	0.6	-0.4	0.5	-0.8	-0.7	0.3	-0.7
Whole body fat-free mass	0.4	2.1	6.7	1.0	-2.1	0.5	0.9	0.1	1.0	-1.2	0.8	2.3	1.1	2.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.8	0.4	-0.6	-0.4	1.0	-0.4	1.0	-0.8	-1.3	-0.4	0.3	-0.3
Illnesses of father: None of the above (group 1)	0.4	0.5	1.2	0.3	0.3	1.1	0.4	1.1	-0.2	0.8	-1.0	0.4	0.7	0.3
Arm fat mass (left)	0.4	1.7	3.9	-0.3	-1.8	-0.8	-0.6	-1.1	0.2	-1.8	2.0	1.5	-0.2	1.9
Hearing aid user	0.4	0.5	1.9	-0.6	-0.4	-0.7	-0.2	-0.9	-0.2	-1.4	0.9	-0.0	-0.6	0.0
Basal metabolic rate	0.4	2.5	8.2	0.6	-2.6	0.0	0.3	-0.4	0.7	-1.6	1.3	2.5	0.6	2.9
Risk taking	0.4	0.5	2.1	0.1	1.4	0.7	0.1	0.7	-0.5	0.7	-0.9	-0.7	0.4	-0.9
Commuting to job workplace: Cycle	0.4	0.5	1.7	0.7	-0.1	-0.8	0.9	-1.0	1.3	0.1	-0.0	-0.7	-0.2	-0.8
Vascular/heart problems diagnosed by doctor	0.4	1.2	4.0	0.1	1.2	-0.5	0.9	-0.9	0.7	-0.3	-1.4	-1.9	-0.2	-2.0
Coronary Artery Disease (CAD)	0.3	0.3	0.7	0.1	0.1	-0.6	0.7	-0.8	0.7	-0.5	-0.1	-0.8	0.0	-0.8
Crohns Disease (2012)	0.3	0.6	1.5	-0.6	0.6	-0.7	0.1	-0.7	-0.2	-0.6	-1.1	-1.2	0.0	-1.2
Ulcerative Colitis	0.3	0.4	1.2	-0.6	0.6	-0.3	-0.1	-0.2	-0.7	0.4	-0.4	-0.8	-1.1	-1.1
Waist Hip Ratio (WHR)	0.3	1.2	4.0	0.9	-1.7	0.5	0.0	-0.1	0.7	0.7	0.4	1.8	1.0	2.0
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.4	-0.8	-1.5	-0.6	-0.6	-0.7	-0.5	-0.9	-0.3	0.7	-0.7	0.7
Sensitivity / hurt feelings	0.3	0.5	2.0	-0.7	0.2	-0.7	-0.5	-0.9	-0.6	-0.1	1.4	-0.4	-0.9	-0.4
Trunk fat-free mass	0.3	1.9	6.2	0.7	-2.2	0.3	0.7	-0.1	0.8	-1.4	0.7	2.2	0.8	2.5
Happiness	0.3	0.4	1.2	-0.5	-0.2	0.1	-0.8	0.1	-0.8	0.4	1.1	0.6	-0.4	0.6
Qualifications: A levels/AS levels or equivalent	0.3	0.8	2.9	-0.4	-1.7	-0.0	-0.9	0.3	-0.7	-0.3	0.7	1.2	-0.4	1.2
Lung cancer (father)	0.3	0.4	1.0	0.2	-0.5	0.6	0.0	0.6	-0.3	0.9	0.4	1.0	0.2	0.9
Trunk predicted mass	0.3	1.9	6.3	0.8	-2.2	0.4	0.7	-0.1	0.8	-1.3	0.7	2.2	0.9	2.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.9	1.0	-0.3	0.3	1.4	-0.0	1.3	-0.5	-0.2	0.1	0.7	0.1
Medication: Amlodipine	0.3	0.4	0.8	0.8	0.9	0.5	0.8	0.7	0.6	-0.4	-0.6	-0.4	0.8	-0.2
Arm fat-free mass (right)	0.3	1.5	4.1	-0.1	-2.0	-0.4	-0.2	-0.8	0.2	-1.8	1.1	1.7	0.0	2.0
Medication: Blood pressure	0.3	0.5	1.9	-1.0	-0.3	-0.5	-1.4	-0.1	-1.1	-0.0	0.4	0.2	-0.9	0.3
Arm predicted mass (right)	0.3	1.6	5.2	-0.2	-1.9	-0.0	-0.5	-0.4	-0.2	-1.4	1.2	2.1	0.1	2.3
Had major operations	0.3	0.3	1.3	0.5	-0.5	-0.4	0.6	-0.5	1.1	-0.7	-0.6	-0.4	0.2	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.0	0.3	-0.9	-0.4	0.7	-0.6	0.8	-0.5	-1.0	0.1	0.2	0.2
Hypertension (Self-reported)	0.3	0.7	2.5	0.1	-0.7	0.3	-0.6	0.6	-0.3	0.1	1.6	1.4	0.3	1.5
Arm fat percentage (left)	0.3	1.1	2.5	-0.7	-1.3	-1.1	-1.0	-1.2	-0.2	-1.6	1.5	0.8	-0.6	1.1
Friendships satisfaction	0.3	0.3	0.8	0.8	0.7	0.4	0.8	0.2	0.7	0.3	0.5	-0.2	0.9	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	3.2	-0.1	-0.5	-1.1	-0.1	-1.0	0.8	-1.8	-0.0	-0.4	-0.4	-0.2
Whole body water mass	0.3	1.9	6.3	0.9	-2.0	0.4	0.8	0.0	1.0	-1.2	0.8	2.2	1.0	2.5
Medication: Bendroflumethiazide	0.3	0.4	1.4	0.6	0.7	0.9	0.3	0.8	0.0	1.2	-0.5	0.2	0.7	0.2
Ever smoked	0.3	0.5	1.2	0.9	-0.4	0.5	1.1	0.4	0.9	0.1	0.5	0.5	0.8	0.6
Arm fat-free mass (left)	0.3	1.6	4.6	0.1	-2.0	-0.2	0.0	-0.6	0.3	-1.8	1.1	1.9	0.2	2.1
Number of operations (self-reported)	0.3	0.5	1.1	0.1	-0.3	0.9	-0.2	0.9	-0.5	0.7	0.8	1.1	0.3	1.0
Fractured/broken bones in last 5 years	0.3	0.3	0.8	-0.4	-0.0	-0.7	-0.4	-0.8	-0.1	-0.9	0.2	-0.5	-0.8	-0.5
Supplements: Calcium	0.3	0.3	0.9	0.2	0.9	0.4	0.1	0.1	0.0	0.8	-0.9	-0.5	0.4	-0.5
Arm predicted mass (left)	0.3	1.4	4.3	0.1	-1.8	-0.2	-0.1	-0.6	0.2	-1.6	1.3	1.8	0.2	2.1
Schizophrenia vs Biploar Disorder	0.2	0.3	1.1	-0.6	-0.2	0.3	-0.9	0.5	-1.0	0.7	-0.2	0.4	0.0	0.3
Worry (Nagel 2018)	0.2	0.3	1.0	-0.5	-1.0	-0.5	-0.6	-0.5	-0.4	-0.3	0.8	0.4	-0.5	0.4
Alzheimer’s Disease (in father)	0.2	0.2	0.9	-0.2	0.5	-0.4	0.1	-0.0	-0.0	-0.3	-0.5	-0.9	-0.2	-0.9
Reaction Time	0.2	0.5	1.1	0.8	0.8	0.3	1.1	0.1	1.0	-0.0	-0.7	-0.7	0.5	-0.6
Breast Cancer	0.2	0.5	1.2	1.1	-0.1	0.6	0.7	0.4	0.7	0.6	0.5	0.8	0.8	0.8
Prostate Cancer	0.2	0.2	0.5	-0.2	-0.7	0.1	-0.2	0.3	-0.6	0.6	-0.1	0.7	-0.3	0.6
Body Mass Index (BMI) (2010)	0.2	0.2	0.6	0.1	0.1	-0.3	0.6	-0.3	0.4	-0.8	-0.3	-0.6	-0.5	-0.6
Smoking Status	0.2	0.5	2.2	0.2	0.3	0.8	0.4	0.8	-0.2	0.5	1.5	0.9	0.4	0.7
Ever had hysterectomy (womb removed)	0.2	0.2	1.5	0.2	-0.1	0.4	0.1	0.2	-0.1	0.1	1.2	0.6	-0.2	0.6
Current tobacco smoking	0.2	0.3	1.2	0.2	1.0	0.4	0.2	0.3	0.2	-0.1	-1.1	-0.7	0.3	-0.7
Maternal smoking around birth	0.2	0.3	0.8	-0.7	0.6	0.1	-0.8	0.1	-0.9	0.4	-0.9	-0.3	0.0	-0.4
Taking other prescription medications	0.2	0.3	0.8	-0.6	0.1	-0.6	-0.4	-0.7	-0.3	-0.0	-0.9	-0.6	-0.6	-0.7
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.7	-0.2	1.1	-0.1	0.1	0.1	-0.2	0.8	-1.0	-1.1	-0.1	-1.3
Stomach or abdominal pain in last month	0.2	0.2	0.7	-0.4	0.3	0.5	-0.7	0.5	-0.8	0.2	-0.6	0.1	0.2	0.1
Body mass index (BMI)	0.2	0.6	3.2	0.4	0.5	-0.6	0.8	-0.6	1.1	-1.8	0.2	-0.7	0.2	-0.5
Past tobacco smoking	0.2	0.3	1.2	-0.7	-0.0	-0.0	-1.1	0.1	-1.0	0.4	-0.6	0.0	-0.6	-0.0
Nervous feelings	0.2	0.3	0.8	0.6	0.9	0.7	0.3	0.7	0.1	0.9	0.2	0.2	0.6	0.1
Had other major operations	0.2	0.3	0.7	-0.4	-0.8	-0.6	0.1	-0.7	0.1	-0.8	-0.6	-0.2	-0.5	-0.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.6	-0.5	0.7	-0.5	-0.6	-0.2	-0.3	0.1	0.4	-0.7	-0.6	-0.8
Heart attack	0.2	0.3	0.8	-0.6	-0.9	-0.4	-0.5	-0.3	-0.4	-0.5	0.6	0.5	-0.8	0.4
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.9	-0.2	-0.9	-0.6	-0.5	-0.5	-0.1	-0.7	0.3	0.1	-0.6	0.1
Arm fat percentage (right)	0.2	0.9	2.3	-0.4	-1.1	-1.0	-0.6	-1.0	0.1	-1.5	1.5	0.7	-0.5	1.0
Prospective memory result	0.2	0.3	0.9	-0.3	0.9	0.5	-0.4	0.7	-0.7	0.2	-0.6	-0.2	-0.2	-0.5
Length of working week for main job	0.2	0.2	1.2	-0.7	-0.1	0.2	-0.6	0.2	-1.1	-0.1	-0.3	0.2	-0.5	-0.1
Suffer from ‘nerves’	0.2	0.3	1.0	0.3	-1.0	-0.1	0.4	-0.2	0.3	-0.4	0.3	0.7	0.1	0.8
Supplements: Vitamin C	0.2	0.2	1.7	0.1	-0.1	-0.2	0.4	-0.2	0.3	-0.3	-1.3	-0.4	-0.2	-0.4
Smoking status: Previous	0.2	0.3	1.7	0.1	-0.6	-0.4	0.4	-0.5	0.4	-0.8	1.3	0.3	-0.0	0.4
Mood swings	0.2	0.4	2.7	-0.2	0.7	-0.1	0.0	-0.5	-0.4	0.3	1.6	0.1	-0.5	0.1
Loneliness, isolation	0.2	0.2	0.6	-0.3	-0.0	-0.6	0.3	-0.8	-0.1	-0.7	0.0	-0.5	-0.6	-0.4
Ever had bowel cancer screening	0.2	0.2	0.5	-0.1	0.0	-0.5	0.5	-0.5	0.3	-0.6	-0.1	-0.7	-0.4	-0.7
Diabetes diagnosed by doctor	0.2	0.4	1.0	-0.5	-0.7	0.0	-0.5	0.1	-0.6	0.2	0.8	1.0	-0.2	0.9
Osteoporosis (self-reported)	0.2	0.3	1.5	-0.5	-0.4	0.2	-1.2	0.2	-0.9	0.2	-0.2	0.2	-0.4	0.1
Medication: Aspirin	0.2	0.2	1.2	-0.4	-0.1	-0.0	-0.6	0.3	-0.5	0.4	-1.1	-0.2	-0.3	-0.3
Smoking status: Current	0.2	0.3	0.9	0.3	0.9	0.5	0.3	0.4	0.2	0.1	-1.0	-0.4	0.4	-0.5
Financial situation satisfaction	0.2	0.3	2.4	0.2	0.1	0.2	0.4	0.2	0.1	0.3	-1.5	-0.4	-0.0	-0.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.8	-0.2	-0.4	-0.3	0.3	-0.6	-0.0	-0.8	-0.9	-0.2	-0.3	-0.2
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.8	-0.5	-0.9	-0.5	-0.4	-0.4	-0.3	-0.6	0.5	0.4	-0.7	0.4
Depression (Nagel 2018)	0.1	0.2	0.7	0.1	-0.1	0.2	0.2	0.2	-0.0	-0.0	0.8	0.7	0.1	0.8
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.2	-0.1	-0.6	0.5	-0.2	0.5	-0.7	-0.0	0.4	1.1	-0.2	1.1
Number of treatments/medications taken	0.1	0.1	0.4	-0.2	-0.2	0.0	-0.3	0.1	-0.4	0.6	0.5	0.4	-0.1	0.4
Angina	0.1	0.1	0.3	0.3	-0.3	-0.1	0.3	0.0	0.6	-0.0	-0.3	-0.1	-0.0	-0.1
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	1.1	0.2	0.4	0.3	0.3	0.2	0.0	0.3	1.1	0.2	0.1	0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.4	-0.1	-0.3	-0.2	-0.1	-0.4	0.3	-0.5	-0.6	-0.1	0.1	-0.1
Qualifications: CSEs or equivalent	0.1	0.1	0.4	0.4	0.1	0.3	0.3	0.3	0.3	0.6	-0.5	0.1	0.3	0.1
Serious illness, injury or assault to yourself	0.1	0.2	0.7	-0.1	-0.4	-0.5	-0.2	-0.2	0.2	-0.6	-0.9	-0.0	-0.5	0.0
Qualifications: None of the above	0.1	0.2	0.6	-0.6	0.2	-0.3	-0.8	-0.2	-0.7	-0.0	0.4	-0.1	-0.5	-0.1
Diabetes (self-reported)	0.1	0.2	0.6	-0.8	-0.5	-0.4	-0.3	-0.3	-0.6	-0.4	0.0	0.3	-0.6	0.2
High blood pressure (siblings)	0.1	0.1	0.4	-0.3	0.0	-0.3	-0.5	0.0	-0.3	-0.4	-0.6	-0.4	-0.1	-0.3
Angina (self-reported)	0.1	0.1	0.2	0.2	-0.1	-0.2	0.2	-0.1	0.5	-0.2	-0.4	-0.4	-0.2	-0.4
Heart disease (mother)	0.1	0.1	0.9	0.1	0.9	0.3	-0.2	0.2	-0.2	0.3	-0.2	-0.4	0.2	-0.3
Knee pain experienced in last month	0.1	0.2	1.3	0.1	1.2	0.4	0.1	0.2	-0.1	0.2	-0.4	-0.3	0.2	-0.3
Long-standing illness, disability or infirmity	0.1	0.2	1.0	0.0	0.7	0.5	-0.1	0.4	-0.3	1.0	-0.6	-0.1	0.1	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.6	0.6	-0.0	-0.1	0.6	-0.0	0.8	0.1	0.1	0.1	0.5	0.2
Mother’s age at death	0.1	0.1	0.2	-0.0	0.4	-0.2	0.1	-0.4	0.1	-0.4	0.2	-0.5	-0.1	-0.5
High cholesterol (Self-reported)	0.1	0.1	0.4	-0.4	0.6	0.1	-0.2	0.1	-0.6	0.3	-0.1	-0.3	-0.3	-0.4
Medication: Lisinopril	0.1	0.1	0.6	0.3	0.1	-0.1	0.3	-0.2	0.5	-0.4	0.8	0.2	0.2	0.4
Hair Pigment	0.0	0.4	2.0	-0.3	-1.4	-0.7	-0.1	-0.9	0.2	-0.2	-0.2	0.3	-0.4	0.5
Tanning	0.0	0.3	2.3	-0.2	0.3	0.1	0.1	0.0	0.0	0.0	1.5	0.5	-0.2	0.4
Overall health rating	0.0	0.1	0.2	-0.1	0.5	-0.1	0.1	-0.1	-0.1	-0.0	-0.4	-0.3	-0.0	-0.2
Number of self-reported non-cancer illnesses	0.0	0.1	0.2	-0.4	-0.2	-0.4	-0.2	-0.4	-0.2	-0.1	-0.4	-0.2	-0.3	-0.2

Hub : Genes

ZNF592

Models

Trait associations