[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr9:125,006,622-129,422,783

Best TWAS P=1.58e-13 · Best GWAS P=5.2e-13 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	PPP6C	0.06	0.10	lasso	3	0.07	3.2e-06	6.2	-5.7	1.2e-08	0.25	0.89	0.10	TRUE
2	GTEx	Adipose Subcutaneous	PSMB7	0.08	0.04	lasso	6	0.04	3.4e-04	-6.3	6.1	9.0e-10	-0.06	0.07	0.92	FALSE
3	GTEx	Artery Tibial	PSMB7	0.07	0.04	enet	7	0.03	4.1e-03	-6.3	7.2	8.3e-13	-0.06	0.02	0.96	TRUE
4	GTEx	Artery Tibial	GAPVD1	0.11	0.16	enet	19	0.16	6.4e-13	-5.7	-6.3	2.5e-10	0.50	0.98	0.02	FALSE
5	GTEx	Artery Tibial	PBX3	0.11	0.07	lasso	2	0.06	8.1e-06	4.5	5.5	5.2e-08	-0.63	0.60	0.08	FALSE
6	GTEx	Artery Tibial	PRPS1P2	0.06	0.06	enet	6	0.05	9.2e-05	5.6	5.6	2.2e-08	-0.21	0.91	0.05	FALSE
7	GTEx	Breast Mammary Tissue (Male)	PPP6C	0.12	0.03	enet	12	0.03	6.5e-02	5.6	-5.4	7.9e-08	0.17	0.07	0.08	TRUE
8	GTEx	Breast Mammary Tissue (Female)	PPP6C	0.14	0.04	lasso	4	0.04	3.1e-02	5.5	-5.5	2.9e-08	0.25	0.36	0.06	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	GOLGA1	0.13	0.00	enet	8	0.06	3.8e-03	5.9	5.3	1.4e-07	-0.25	0.40	0.08	TRUE
10	GTEx	Cells Transformed fibroblasts	MAPKAP1	0.04	0.03	lasso	3	0.02	6.5e-03	-7.1	-7.0	1.8e-12	0.92	0.04	0.92	FALSE
11	GTEx	Cells Transformed fibroblasts	PBX3	0.05	0.02	enet	7	0.00	1.4e-01	-5.8	6.0	1.6e-09	-0.86	0.14	0.65	FALSE
12	GTEx	Cells Transformed fibroblasts	PRPS1P2	0.09	0.11	enet	8	0.13	9.6e-10	5.9	5.7	1.5e-08	-0.18	0.94	0.06	FALSE
13	GTEx	Colon Sigmoid	PSMB7	0.15	0.10	lasso	3	0.09	3.3e-04	-6.6	6.5	6.3e-11	-0.04	0.02	0.96	FALSE
14	GTEx	Colon Transverse	PRPS1P2	0.11	0.10	lasso	1	0.08	1.8e-04	5.9	5.9	3.3e-09	-0.25	0.50	0.25	FALSE
15	GTEx	Esophagus Mucosa	PPP6C	0.07	0.07	enet	21	0.08	7.1e-06	5.8	-5.4	6.1e-08	0.19	0.96	0.04	TRUE
16	GTEx	Esophagus Mucosa	PRPS1P2	0.07	0.08	lasso	3	0.07	1.5e-05	5.6	5.6	2.7e-08	-0.23	0.76	0.12	FALSE
17	GTEx	Esophagus Muscularis	RABGAP1	0.10	0.01	lasso	5	0.03	3.7e-03	-4.8	5.5	3.7e-08	0.02	0.12	0.73	FALSE
18	GTEx	Esophagus Muscularis	PBX3	0.12	0.08	lasso	7	0.09	4.2e-06	4.5	5.7	9.7e-09	-0.65	0.70	0.29	FALSE
19	GTEx	Heart Atrial Appendage	PBX3	0.10	0.08	lasso	6	0.04	9.0e-03	4.7	5.2	2.5e-07	-0.57	0.27	0.16	TRUE
20	GTEx	Muscle Skeletal	GAPVD1	0.13	0.10	lasso	3	0.09	4.7e-09	-5.7	5.7	1.2e-08	-0.52	0.98	0.02	TRUE
21	GTEx	Nerve Tibial	GAPVD1	0.17	0.08	lasso	10	0.10	9.3e-08	5.8	-6.5	1.0e-10	0.35	0.96	0.04	FALSE
22	GTEx	Pancreas	PBX3	0.13	0.02	enet	26	0.00	3.2e-01	-5.9	6.4	1.3e-10	-0.66	0.05	0.81	TRUE
23	GTEx	Pancreas	OLFML2A	0.15	0.03	lasso	5	0.09	1.2e-04	7.1	7.0	2.0e-12	-0.06	0.01	0.92	TRUE
24	GTEx	Pancreas	PRPS1P2	0.16	0.13	lasso	6	0.12	8.7e-06	5.6	5.7	9.7e-09	-0.22	0.91	0.05	FALSE
25	GTEx	Testis	PBX3	0.19	0.22	lasso	3	0.20	4.7e-09	4.7	5.2	1.5e-07	-0.55	0.78	0.21	FALSE
26	GTEx	Thyroid	NEK6	0.20	0.21	lasso	4	0.20	1.3e-15	-6.6	6.0	2.7e-09	-0.05	0.00	1.00	FALSE
27	GTEx	Thyroid	PSMB7	0.06	0.04	lasso	2	0.06	4.1e-05	-6.3	6.6	5.4e-11	-0.07	0.02	0.97	FALSE
28	GTEx	Thyroid	GAPVD1	0.05	0.05	enet	13	0.01	6.6e-02	-5.8	-6.1	1.2e-09	0.50	0.86	0.03	FALSE
29	GTEx	Thyroid	PBX3	0.07	0.00	lasso	6	0.01	4.7e-02	4.8	6.1	1.3e-09	-0.34	0.24	0.46	FALSE
30	METSIM	Adipose	RABGAP1	0.04	0.03	lasso	9	0.05	1.2e-08	-5.0	5.2	1.9e-07	0.00	0.07	0.93	FALSE
31	NTR	Blood	MAPKAP1	0.03	0.01	blup	441	0.02	2.3e-07	-6.1	-7.4	1.6e-13	0.80	0.30	0.69	TRUE
32	NTR	Blood	RABGAP1	0.03	0.01	blup	460	0.02	4.3e-06	3.4	-5.5	2.8e-08	-0.02	0.19	0.81	FALSE
33	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC100129034	0.12	0.00	lasso	4	0.04	1.7e-03	-6.1	-5.7	1.2e-08	-0.04	0.01	0.50	FALSE
34	The Cancer Genome Atlas	Esophageal Carcinoma	PPP6C	0.17	0.04	blup	46	0.08	1.7e-03	7.0	-6.5	6.1e-11	0.18	0.02	0.63	TRUE
35	The Cancer Genome Atlas	Glioblastoma Multiforme	RABGAP1	0.17	0.17	lasso	7	0.21	5.6e-07	-4.8	-5.5	3.5e-08	-0.01	0.03	0.96	FALSE
36	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RABGAP1	0.02	0.01	blup	56	0.01	7.4e-03	-5.6	-5.4	8.2e-08	0.01	0.02	0.84	FALSE
37	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPP6C	0.07	0.08	lasso	3	0.09	5.4e-10	5.5	-5.2	2.3e-07	0.21	0.91	0.09	FALSE
38	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RABGAP1	0.04	0.04	lasso	4	0.04	2.9e-03	-5.1	-5.2	1.7e-07	0.00	0.03	0.60	FALSE
39	The Cancer Genome Atlas	Brain Lower Grade Glioma	PPP6C	0.02	0.02	lasso	2	0.01	1.5e-02	5.9	-5.9	4.4e-09	0.24	0.06	0.05	FALSE
40	The Cancer Genome Atlas	Lung Adenocarcinoma	PPP6C	0.02	0.02	lasso	4	0.02	7.6e-04	5.6	-5.7	1.3e-08	0.22	0.60	0.11	FALSE
41	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	NEK6	0.14	0.02	blup	87	0.05	2.8e-03	2.8	-5.2	2.0e-07	0.05	0.02	0.69	FALSE
42	The Cancer Genome Atlas	Prostate Adenocarcinoma	GAPVD1	0.02	0.04	enet	4	0.01	9.8e-03	-5.5	5.9	3.4e-09	-0.51	0.17	0.18	TRUE
43	The Cancer Genome Atlas	Prostate Adenocarcinoma	PBX3	0.03	0.03	blup	65	0.04	5.4e-05	4.6	5.3	9.7e-08	-0.56	0.48	0.48	FALSE
44	The Cancer Genome Atlas	Prostate Adenocarcinoma	PPP6C	0.06	0.08	lasso	7	0.07	1.8e-07	5.9	-5.9	4.1e-09	0.21	0.85	0.15	TRUE
45	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMB7	0.03	0.04	lasso	4	0.04	1.2e-04	-6.0	6.3	3.3e-10	-0.03	0.05	0.90	FALSE
46	The Cancer Genome Atlas	Stomach Adenocarcinoma	PPP6C	0.05	0.04	blup	46	0.03	3.8e-03	5.6	-5.8	5.6e-09	0.23	0.49	0.16	FALSE
47	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RABGAP1	0.12	0.05	blup	58	0.06	4.2e-03	-5.2	-5.8	8.0e-09	0.00	0.03	0.95	TRUE
48	The Cancer Genome Atlas	Thyroid Carcinoma	PPP6C	0.08	0.13	enet	9	0.13	5.5e-13	5.9	-5.4	6.4e-08	0.23	0.83	0.17	FALSE
49	The Cancer Genome Atlas	Thyroid Carcinoma	PSMB7	0.06	0.06	lasso	4	0.04	3.7e-05	-5.6	5.6	2.6e-08	-0.04	0.28	0.71	FALSE