[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr15:88,317,958-92,120,170

Best TWAS P=2.11e-23 · Best GWAS P=5.19e-58 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
36	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	MFGE8	0.18	0.01	lasso	4	0.04	9.9e-03	7.32	-10.0	2.1e-23	-0.01	0.04	0.04	TRUE
26	The Cancer Genome Atlas	Colon Adenocarcinoma	HAPLN3	0.14	0.04	lasso	4	0.08	1.7e-05	0.79	-9.9	5.5e-23	0.43	0.05	0.58	TRUE
5	GTEx	Brain Cortex	HAPLN3	0.40	-0.01	lasso	5	-0.01	6.0e-01	-3.33	-7.0	3.7e-12	-0.04	0.04	0.15	TRUE
11	GTEx	Skin Sun Exposed Lower leg	CRTC3	0.10	0.08	lasso	3	0.05	7.5e-05	6.58	-6.9	4.0e-12	-0.07	0.02	0.98	TRUE
27	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IQGAP1	0.15	0.05	enet	10	0.08	2.5e-09	5.87	6.9	7.0e-12	0.07	0.03	0.97	TRUE
21	YFS	Blood	IQGAP1	0.18	0.17	enet	46	0.20	5.8e-65	5.66	6.8	8.6e-12	0.06	0.86	0.14	TRUE
34	The Cancer Genome Atlas	Lung Adenocarcinoma	IQGAP1	0.06	0.04	blup	94	0.03	5.8e-05	5.51	6.6	3.2e-11	0.07	0.08	0.91	TRUE
18	NTR	Blood	IQGAP1	0.03	0.04	enet	10	0.04	1.5e-12	6.61	6.6	3.7e-11	0.06	0.02	0.98	TRUE
7	GTEx	Esophagus Gastroesophageal Junction	ZNF774	0.16	0.16	lasso	2	0.11	7.8e-05	6.35	6.5	6.1e-11	0.05	0.02	0.96	TRUE
17	METSIM	Adipose	POLG	0.04	0.02	blup	469	0.03	4.9e-05	-3.44	-6.2	5.7e-10	-0.08	0.96	0.00	TRUE
20	YFS	Blood	FURIN	0.11	0.03	enet	37	0.06	8.3e-19	3.63	5.8	5.5e-09	0.08	1.00	0.00	TRUE
3	GTEx	Artery Aorta	MFGE8	0.34	0.07	lasso	8	0.11	1.7e-06	-1.73	5.8	5.6e-09	-0.05	0.85	0.08	TRUE
24	The Cancer Genome Atlas	Breast Invasive Carcinoma	IQGAP1	0.03	0.02	blup	94	0.02	6.5e-05	5.44	5.8	6.6e-09	0.03	0.10	0.88	TRUE
10	GTEx	Lung	ZNF774	0.06	0.09	enet	6	0.03	1.5e-03	6.35	5.8	8.9e-09	0.04	0.04	0.96	TRUE
2	CommonMind	Brain Pre-frontal Cortex	ZNF774	0.20	0.08	lasso	7	0.14	1.8e-16	5.37	-5.2	2.6e-07	-0.01	0.49	0.51	TRUE
16	METSIM	Adipose	IQGAP1	0.11	0.08	enet	32	0.12	3.9e-17	6.65	6.6	5.0e-11	0.04	0.02	0.98	FALSE
38	The Cancer Genome Atlas	Stomach Adenocarcinoma	IQGAP1	0.12	0.07	lasso	4	0.07	1.4e-05	6.65	6.5	1.1e-10	0.04	0.01	0.99	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF774	0.06	0.06	lasso	3	0.04	1.2e-05	6.35	-6.3	2.2e-10	-0.05	0.00	1.00	FALSE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	IQGAP1	0.11	0.03	enet	8	0.06	1.4e-06	5.87	6.3	2.2e-10	0.10	0.07	0.92	FALSE
6	GTEx	Cells Transformed fibroblasts	IQGAP1	0.13	0.06	enet	19	0.11	9.2e-09	4.88	6.3	2.3e-10	0.05	0.04	0.94	FALSE
23	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	IQGAP1	0.04	0.03	lasso	4	0.02	6.5e-03	6.61	6.3	2.4e-10	0.06	0.01	0.89	FALSE
8	GTEx	Esophagus Mucosa	CRTC3	0.08	0.07	enet	7	0.04	6.1e-04	6.15	-6.2	6.3e-10	-0.04	0.04	0.96	FALSE
19	YFS	Blood	CRTC3	0.02	0.01	blup	503	0.01	4.2e-05	6.72	-6.0	1.7e-09	-0.06	0.02	0.98	FALSE
25	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	IQGAP1	0.15	0.09	lasso	4	0.12	1.9e-06	6.42	6.0	2.1e-09	0.07	0.01	0.98	FALSE
29	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IQGAP1	0.07	0.06	blup	94	0.07	9.5e-09	6.62	6.0	2.1e-09	0.04	0.02	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	IQGAP1	0.19	0.21	lasso	5	0.20	1.7e-24	5.87	5.8	5.8e-09	0.03	0.73	0.27	FALSE
14	GTEx	Testis	ZNF774	0.13	0.09	lasso	4	0.08	1.5e-04	5.36	-5.8	8.7e-09	-0.03	0.23	0.47	FALSE
13	GTEx	Testis	FANCI	0.19	0.04	enet	21	0.09	1.3e-04	-3.39	-5.6	2.0e-08	-0.08	0.20	0.05	FALSE
12	GTEx	Stomach	IQGAP1	0.21	0.14	enet	17	0.18	8.3e-09	5.36	5.6	2.1e-08	0.04	0.07	0.93	FALSE
15	GTEx	Whole Blood	MFGE8	0.12	0.14	lasso	4	0.13	9.3e-12	-5.54	-5.6	2.1e-08	-0.01	1.00	0.00	FALSE
40	The Cancer Genome Atlas	Thyroid Carcinoma	IQGAP1	0.06	0.04	blup	95	0.08	3.0e-08	5.36	5.5	2.8e-08	0.04	0.04	0.96	FALSE
30	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZNF774	0.04	0.00	enet	7	0.01	5.1e-02	6.35	5.5	3.4e-08	0.06	0.01	0.90	FALSE
31	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	IQGAP1	0.06	0.05	blup	94	0.04	2.6e-03	3.96	5.5	3.6e-08	0.03	0.10	0.63	FALSE
4	GTEx	Artery Aorta	ZNF774	0.22	0.24	enet	16	0.23	7.6e-13	5.37	5.5	4.5e-08	0.06	0.22	0.78	FALSE
22	YFS	Blood	MRPS11	0.03	0.00	bslmm	436	0.01	9.6e-05	0.35	-5.3	1.1e-07	0.07	0.13	0.05	FALSE
28	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ZNF774	0.04	0.02	blup	57	0.02	1.2e-03	3.76	-5.3	1.2e-07	-0.04	0.03	0.82	FALSE
32	The Cancer Genome Atlas	Brain Lower Grade Glioma	CRTC3	0.03	0.01	blup	78	0.01	4.2e-02	3.81	-5.2	1.8e-07	-0.04	0.02	0.59	FALSE
35	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IQGAP1	0.02	0.02	blup	94	0.02	6.2e-03	5.61	5.2	2.0e-07	0.03	0.08	0.38	FALSE
9	GTEx	Esophagus Muscularis	ZNF774	0.18	0.19	lasso	5	0.18	4.1e-11	5.24	-5.2	2.1e-07	-0.06	0.49	0.51	FALSE
39	The Cancer Genome Atlas	Testicular Germ Cell Tumors	IQGAP1	0.14	0.07	lasso	2	0.08	8.5e-04	4.78	5.2	2.3e-07	0.05	0.03	0.79	FALSE