TWAS hub - MRPS11

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Stomach	0.3490	0.1090	0.00360	-0.005	NA	0.002	NA	0.009	0.700	NA	0.2500	NA	0.110
2	YFS	Blood	0.0338	0.0131	0.00094	0.002	0.009	0.006	0.011	0.004	0.075	0.00041	0.0028	9.6e-05	0.011

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Noisy workplace	5.8	7.1	9.5	3.1	2.2
Height	4.9	94.1	102.0	-9.3	-10.1
Medication: Bendroflumethiazide	4.5	6.8	13.5	-3.7	0.2
Standing height	4.3	42.2	45.5	-6.7	-6.2
Forced vital capacity (FVC)	4.1	15.9	16.9	-3.9	-4.1
Alcohol intake versus 10 years previously	4.0	6.0	11.5	3.4	-0.8
Comparative height size at age 10	3.5	19.3	28.2	-3.2	-5.3
Ever had stillbirth, spontaneous miscarriage or termination	3.4	3.6	6.8	0.7	2.6
Forced vital capacity (FVC), Best measure	3.2	11.7	11.9	-3.4	-3.4
Serious illness, injury or assault of a close relative in last 2 years	3.1	3.6	6.1	2.5	1.1
Depression (self-reported)	3.1	3.7	6.6	0.9	-2.6
Average weekly champagne plus white wine intake	3.0	4.1	6.3	-2.5	-1.4
Hearing difficulty/problems: Yes	2.9	4.4	7.5	1.2	2.7
Ever highly irritable/argumentative for 2 days	2.9	3.5	6.9	0.2	-2.6
Chronic bronchitis/emphysema (mother)	2.8	3.3	5.1	-2.3	-1.2
Tinnitus: Yes, now most or all of the time	2.8	3.2	6.2	-0.5	2.5
Forced expiratory volume in 1-second (FEV1)	2.5	8.5	9.6	-2.7	-3.1
Osteoporosis (self-reported)	2.5	3.1	5.7	2.4	-0.7
Ever had prostate specific antigen (PSA) test	2.5	2.9	4.9	2.2	0.9
Medication: Ramipril	2.4	3.1	4.0	-1.5	-2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	2.4	3.1	5.3	0.9	-2.3
Number of full sisters	2.2	2.7	3.7	1.3	1.9
Supplements: Zinc	2.1	2.3	2.9	1.7	1.3
Sitting height	2.1	15.0	19.4	-4.4	-3.2
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.8	7.3	-2.5	-2.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.1	2.5	4.1	-0.9	-2.0
LDL Cholesterol	2.0	3.2	5.8	-2.4	-0.8
Medication for hormone replacement therapy	2.0	2.2	4.2	2.0	0.6
Hair/balding pattern: Pattern 4	2.0	4.9	9.6	0.5	3.1
Worry too long after embarrassment	2.0	3.4	5.3	-2.3	-1.2
Medication: Blood pressure	2.0	3.7	6.8	-2.6	-0.8
Relative age voice broke	1.9	3.0	5.9	0.3	2.4
HbA1C	1.8	2.0	3.4	-1.9	0.8
Breastfed as a baby	1.8	2.3	3.1	-1.2	1.8
Financial situation satisfaction	1.8	2.3	3.8	0.9	-2.0
Number of operations (self-reported)	1.8	2.7	4.0	2.0	1.2
Bipolar Disorder or Schizophrenia	1.7	4.2	5.5	-1.7	-2.3
Schizophrenia vs Biploar Disorder	1.7	2.2	4.4	-2.1	-0.3
Lupus	1.7	2.5	4.9	0.3	2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	2.7	1.6	-1.4
Ever depressed for a whole week	1.7	2.1	2.3	1.4	1.5
Heart disease (siblings)	1.7	2.1	4.2	2.0	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.5	4.0	2.0	1.8
Medication: Simvastatin	1.6	2.3	4.0	-2.0	0.8
Birth weight of first child	1.6	2.9	5.7	-0.3	-2.4
Qualifications: nursing, teaching	1.6	2.4	4.2	-2.1	-0.8
Had other major operations	1.5	1.8	2.4	1.6	-1.1
Illnesses of mother	1.5	1.8	3.7	0.0	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.1	5.6	-2.4	-0.8
Smoking Status	1.4	3.4	5.4	1.2	-2.3
Medication: Amlodipine	1.4	1.9	2.9	-1.0	1.7
Number of children fathered	1.4	1.5	2.0	1.4	1.0
Medication: Omeprazole	1.4	1.7	1.8	1.3	1.3
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	2.0	1.4	1.1
Commuting to job workplace: Walk	1.4	1.5	2.9	-1.7	0.1
Schizophrenia (2018)	1.3	2.7	3.3	-1.4	-1.8
Major Depression (MDD)	1.3	1.5	2.2	0.9	-1.5
Angina	1.3	1.7	3.3	0.3	1.8
Falls in the last year	1.3	1.8	2.7	0.9	1.6
Leg fat percentage (right)	1.3	4.7	9.0	3.0	0.6
Long-standing illness, disability or infirmity	1.3	2.0	3.9	0.2	2.0
Medication: Aspirin	1.3	1.7	3.3	0.3	1.8
Ever taken oral contraceptive pill	1.3	1.5	1.5	-1.2	1.2
Commuting to job workplace: Cycle	1.3	1.6	3.1	0.1	1.8
Pain experienced in last month	1.3	2.2	2.6	-1.6	-1.3
Frequency of depressed mood in last 2 weeks	1.2	1.6	3.3	0.0	-1.8
Pulse wave peak to peak time	1.2	1.4	2.7	-0.3	-1.6
Mouth/teeth dental problems: Mouth ulcers	1.2	1.9	3.7	-0.0	1.9
Illnesses of father: None of the above (group 1)	1.2	1.5	2.7	-1.7	-0.5
Smoking status: Current	1.2	1.9	2.0	1.4	-1.3
Leg fat percentage (left)	1.2	4.5	8.8	3.0	0.5
Basal cell carcinoma (self-reported)	1.2	1.4	2.2	-0.8	-1.5
Alcohol drinker status: Previous	1.2	1.4	1.8	-1.0	1.3
Bipolar Disorder (2018)	1.1	1.8	2.8	-0.9	-1.7
Schizophrenia (2014)	1.1	2.3	3.3	-1.8	-1.2
Serious illness, injury or assault to yourself	1.1	1.3	2.2	-1.5	-0.7
Supplements: Glucosamine	1.1	1.5	2.9	-0.1	-1.7
Leg predicted mass (left)	1.1	5.6	6.6	-2.6	-2.1
Trunk fat-free mass	1.1	6.1	8.6	-2.9	-1.9
Medication: Lansoprazole	1.1	1.3	2.1	-1.5	-0.7
Trunk predicted mass	1.1	6.3	8.9	-3.0	-1.9
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	3.4	-1.9	-0.3
Medication: Ventolin 100micrograms inhaler	1.1	1.4	2.5	1.6	0.5
Medication for pain relief, constipation, heartburn	1.1	1.8	3.4	-0.5	-1.8
Heart disease (mother)	1.1	1.3	2.4	0.5	1.6
Illness, injury, bereavement, stress in last 2 years	1.1	1.4	2.7	-1.6	0.2
Supplements: Vitamin C	1.1	1.3	2.4	1.6	-0.3
Leg fat-free mass (right)	1.1	5.9	7.5	-2.7	-2.1
Leg predicted mass (right)	1.1	6.0	7.5	-2.7	-2.1
Risk taking	1.1	1.6	1.9	1.1	-1.4
Myopia	1.1	1.6	2.4	-0.9	-1.6
Alzheimer’s Disease (in father)	1.0	1.1	2.1	0.3	1.5
Crohns Disease (2012)	1.0	1.5	3.0	-0.3	-1.7
BMI	1.0	5.6	6.6	2.6	2.2
Severe depression (siblings)	1.0	1.2	1.9	1.4	0.7
Leg fat-free mass (left)	1.0	5.5	6.4	-2.5	-2.2
Number of incorrect matches in round	1.0	1.6	1.8	-1.3	1.2
Alcohol usually taken with meals	1.0	1.6	2.1	-1.4	1.0
Allergy	1.0	2.4	2.5	-1.6	-1.5
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	2.3	-0.6	1.5
Father’s age at death	1.0	1.3	2.7	0.2	1.6
Medication: Cholesterol lowering	1.0	1.5	2.8	0.5	1.7
Angina (self-reported)	1.0	1.3	2.5	0.2	1.6
Medication: Aspirin	1.0	1.3	2.6	-0.0	1.6
Illnesses of father: Heart disease	1.0	1.3	2.5	1.6	-0.4
Whole body fat-free mass	1.0	5.7	7.2	-2.7	-2.1
Mood swings	1.0	1.7	2.6	-0.9	-1.6
Whole body water mass	1.0	5.9	7.9	-2.8	-2.0
Bipolar Disorder (2011)	0.9	0.9	0.9	0.9	-0.9
Ever had hysterectomy (womb removed)	0.9	1.0	1.9	1.4	-0.4
Taking other prescription medications	0.9	1.3	1.7	1.3	-0.9
Multivitamins +/- minerals	0.9	1.1	1.4	-1.2	0.9
Medication: Atenolol	0.9	1.1	1.1	-1.1	1.0
Pulse wave Arterial Stiffness index	0.9	1.0	2.1	0.0	1.4
Glaucoma (self-reported)	0.9	1.1	1.4	-0.9	1.2
Birth weight	0.9	1.9	3.7	0.0	-1.9
High blood pressure (siblings)	0.9	1.4	2.0	-1.4	0.9
Wheeze or whistling in the chest in last year	0.9	1.7	2.3	1.5	1.0
Leg pain on walking	0.9	1.1	2.0	-1.4	0.3
Medication: Lisinopril	0.9	1.2	2.1	-1.4	-0.5
Depressed Affect (Nagel 2018)	0.8	1.6	3.0	-0.5	-1.7
Neuroticism (Nagel 2018)	0.8	1.8	3.5	0.5	-1.9
Verbal and Numeric Reasoning (VNR)	0.8	1.9	3.8	-1.9	-0.3
Triglycerides	0.8	1.2	2.5	-0.1	-1.6
Hand grip strength (left)	0.8	2.1	4.2	-0.3	-2.0
Medication: Co-codamol	0.8	0.9	1.6	1.3	0.4
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	1.4	1.2	0.7
Hayfever, allergic rhinitis or eczema	0.8	1.8	2.1	1.2	1.4
Stomach or abdominal pain in last month	0.8	1.0	1.3	1.1	-0.8
Qualifications: None of the above	0.8	1.6	3.1	1.8	0.4
Neuroticism score	0.8	1.6	2.3	-0.9	-1.5
Happiness	0.8	0.9	1.7	-0.4	-1.3
Lung cancer (father)	0.8	0.9	1.8	-1.3	-0.0
Impedance of arm (left)	0.8	3.6	5.8	-1.2	-2.4
Arm fat-free mass (right)	0.8	4.0	4.2	-2.0	-2.1
Qualifications: College or University degree	0.8	2.6	3.0	-1.7	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	1.9	0.3	-1.4
Arm predicted mass (right)	0.8	4.2	5.2	-1.8	-2.3
Age at last live birth	0.8	1.2	1.8	-1.3	-0.8
Commuting to job workplace: Car/motor vehicle	0.8	0.9	1.5	0.5	-1.2
Average weekly red wine intake	0.8	1.2	2.3	-0.2	1.5
Basal metabolic rate	0.8	4.7	5.2	-2.3	-2.0
Coronary Artery Disease (CAD)	0.7	0.9	1.6	1.3	0.4
Neuroticism	0.7	1.8	3.5	0.2	-1.9
Diabetes (mother)	0.7	0.9	1.7	-1.3	-0.2
Current tobacco smoking	0.7	1.2	1.6	1.3	-0.9
Maternal smoking around birth	0.7	1.0	1.6	0.7	-1.3
Body mass index (BMI)	0.7	3.2	4.7	2.2	1.3
Hair/balding pattern: Pattern 2	0.7	0.9	1.3	-0.7	-1.2
Worrier / anxious feelings	0.7	1.4	1.6	-1.1	-1.3
Emphysema/chronic bronchitis	0.7	0.8	0.9	0.9	-0.8
Mean time to correctly identify matches	0.7	1.3	1.9	0.9	1.4
Illnesses of siblings: Diabetes	0.7	0.9	1.7	-0.3	-1.3
Eye problems/disorders: Cataract	0.7	0.8	0.9	1.0	-0.9
Arm fat-free mass (left)	0.7	3.4	4.0	-1.6	-2.0
Unable to work because of sickness or disability	0.7	0.9	1.0	0.9	1.0
Ulcerative Colitis (UC)	0.6	1.1	1.9	0.5	1.4
Prostate Cancer	0.6	0.8	1.6	0.2	1.2
HDL Cholesterol	0.6	1.0	2.0	-0.1	1.4
Allergy or Eczema	0.6	1.5	3.1	-0.1	1.8
Lung FEV1/FVC ratio	0.6	2.9	5.2	2.3	0.9
Sensitivity / hurt feelings	0.6	1.0	2.0	-1.4	-0.3
Ever used hormone-replacement therapy (HRT)	0.6	0.7	1.3	1.2	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	1.7	-0.5	-1.3
Diabetes (self-reported)	0.6	0.9	1.6	-0.5	1.3
Impedance of arm (right)	0.6	2.8	5.2	-0.6	-2.3
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.1	2.1	-1.4	0.2
Exposure to tobacco smoke at home	0.6	0.7	1.1	-0.6	1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	1.6	0.4	-1.3
Peak expiratory flow (PEF)	0.6	1.4	2.7	0.3	-1.7
Pulse wave reflection index	0.6	0.8	1.1	1.0	0.7
Alcohol intake frequency.	0.6	1.4	2.6	0.5	1.6
Osteoarthritis (self-reported)	0.6	0.8	1.2	-0.6	1.1
Guilty feelings	0.6	0.9	1.5	-0.5	-1.2
Hearing aid user	0.6	0.7	0.9	-0.9	0.7
Pain type(s) experienced in last month: Hip pain	0.6	0.8	1.3	0.6	1.1
Medication: Atorvastatin	0.6	0.8	0.9	0.8	0.9
Average weekly beer plus cider intake	0.6	0.9	1.6	1.3	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.0	1.0	0.6
Impedance of whole body	0.6	3.0	6.1	-0.1	-2.5
Intelligence (Savage-Jansen 2018)	0.5	1.4	2.6	-1.6	-0.6
Body Mass Index (BMI) (2010)	0.5	0.7	0.7	-0.8	-0.8
Heel T-Score	0.5	4.1	6.6	1.3	2.6
Impedance of leg (right)	0.5	2.3	3.4	1.1	-1.9
Age when periods started (menarche)	0.5	1.2	1.5	-1.0	-1.2
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	0.7	0.6	0.9
Impedance of leg (left)	0.5	2.5	3.8	1.0	-2.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.7	1.1	0.4	-1.1
Pain all over the body in last month	0.5	0.6	0.7	0.9	-0.6
Loud music exposure frequency	0.5	0.6	0.9	0.9	-0.5
Blood clot in the leg (DVT)	0.5	0.6	1.1	-0.2	1.1
Age at first live birth	0.5	0.9	1.2	-0.8	1.1
Medication: Blood pressure	0.5	0.9	1.1	-1.0	0.8
Number of self-reported non-cancer illnesses	0.5	0.8	1.4	0.5	1.2
Commuting to job workplace: Public transport	0.5	0.6	1.0	-0.4	1.0
High cholesterol (Self-reported)	0.5	0.9	1.3	-1.2	0.6
Age started oral contraceptive pill	0.5	0.6	0.9	0.5	0.9
Supplements: Calcium	0.5	0.5	0.7	0.9	0.5
Arm predicted mass (left)	0.5	2.5	2.7	-1.5	-1.6
Age at First Birth	0.4	0.6	0.7	-0.8	0.7
Mean Putamen Volume	0.4	0.4	0.8	0.9	-0.3
Neuroticism (2016)	0.4	0.5	0.7	-0.8	-0.6
Type 2 Diabetes (T2D) (2012)	0.4	0.5	0.9	-0.2	-1.0
Systolic Blood Pressure	0.4	1.9	2.9	-1.7	1.0
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	0.9	-0.2	1.0
Medication: Metformin	0.4	0.5	1.0	0.3	1.0
Hand grip strength (right)	0.4	1.0	1.4	-1.2	-0.7
Townsend deprivation index at recruitment	0.4	0.6	1.2	0.1	1.1
Qualifications: CSEs or equivalent	0.4	0.5	0.9	-0.4	-0.9
Chronic bronchitis/emphysema (father)	0.4	0.4	0.7	0.8	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	1.0	1.0	0.9
Heart attack	0.4	0.5	0.7	-0.5	0.8
Arm fat percentage (right)	0.4	1.6	3.0	1.7	0.4
Hair/balding pattern: Pattern 3	0.4	0.5	0.7	0.8	0.6
Gout (self-reported)	0.4	0.5	0.7	-0.9	-0.5
Shortness of breath walking on level ground	0.4	0.4	0.9	0.9	0.1
Neck or shoulder pain in last month	0.4	0.6	1.1	0.3	1.1
Had major operations	0.4	0.4	0.6	0.7	0.6
Hypertension (Self-reported)	0.4	1.0	1.7	-1.3	0.5
Smoking status: Previous	0.4	0.6	1.2	0.2	1.1
Friendships satisfaction	0.4	0.5	0.6	-0.6	-0.8
Medication for cholesterol	0.4	0.6	1.1	1.0	-0.4
Breast cancer (self-reported)	0.4	0.4	0.5	0.6	0.7
Asthma (self-reported)	0.4	0.8	1.5	1.2	-0.1
Mother’s age at death	0.4	0.5	0.8	0.5	0.9
Fractured/broken bones in last 5 years	0.4	0.5	0.6	-0.6	-0.8
Cholesterol lowering medication	0.4	0.5	0.9	-1.0	-0.4
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.6	-0.6	0.8
Depression (Nagel 2018)	0.3	0.4	0.8	0.2	-0.9
Reaction Time	0.3	0.6	0.7	0.6	0.9
Ovarian Cancer	0.3	0.4	0.6	0.8	0.3
Rheumatoid Arthritis	0.3	0.5	0.6	0.8	-0.6
Chronotype (morning person)	0.3	0.6	1.1	1.0	0.4
Tanning	0.3	4.0	4.9	1.8	2.2
Average weekly spirits intake	0.3	0.4	0.7	0.9	-0.2
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	0.4	0.5	0.6
Systolic blood pressure, automated reading	0.3	1.0	1.9	0.2	1.4
Average weekly fortified wine intake	0.3	0.4	0.7	-0.3	-0.8
High blood pressure	0.3	1.0	1.8	-1.4	0.3
Hearing difficulty/problems with background noise	0.3	0.5	0.9	-0.4	1.0
Had menopause	0.3	0.4	0.4	-0.7	0.6
Mouth/teeth dental problems	0.3	0.5	1.0	-1.0	0.1
Weight	0.3	1.5	2.3	-0.9	-1.5
Number of live births	0.3	0.4	0.4	-0.6	-0.6
Asthma	0.3	0.7	1.4	1.2	0.0
Length of working week for main job	0.3	0.3	0.6	-0.3	0.8
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.8	0.3	-0.9
Body fat percentage	0.3	1.3	2.5	1.6	-0.4
Health satisfaction	0.3	0.4	0.5	0.7	-0.5
Eye problems/disorders: None of the above	0.3	0.4	0.8	-0.9	0.1
Medication: Allopurinol	0.3	0.4	0.6	-0.8	-0.3
Leg fat mass (right)	0.3	1.2	2.2	1.5	-0.3
Pulse rate, automated reading	0.3	0.9	1.7	-1.3	0.2
Overall health rating	0.3	0.6	1.2	1.1	0.3
Arm fat percentage (left)	0.3	1.1	2.2	1.5	0.3
Mineral and other dietary supplements	0.3	0.4	0.5	-0.5	0.7
Miserableness	0.3	0.6	1.2	-0.1	-1.1
Diastolic blood pressure, automated reading	0.3	0.8	0.9	-0.8	0.9
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	0.6	-0.1	0.8
Pack years of smoking	0.3	0.5	0.6	0.5	0.8
Leg fat mass (left)	0.3	1.0	2.0	1.4	-0.3
Alzheimer’s Disease (in mother)	0.2	0.2	0.4	-0.3	0.6
Alzheimer’s Disease (including proxy)	0.2	0.3	0.6	-0.0	0.7
Blood Red Count	0.2	2.1	3.6	1.9	0.7
Waist Hip Ratio (WHR)	0.2	0.9	1.8	-0.0	-1.3
Hypothyroidism (self reported)	0.2	0.4	0.6	-0.3	-0.8
Type 2 Diabetes (T2D) (2018)	0.2	0.4	0.8	-0.9	0.3
Relative age of first facial hair	0.2	0.5	0.9	-0.9	-0.3
Trunk fat percentage	0.2	0.9	1.2	0.8	-1.1
Fed-up feelings	0.2	0.4	0.8	0.1	-0.9
Trunk fat mass	0.2	1.1	2.1	0.0	-1.4
Nervous feelings	0.2	0.4	0.6	-0.6	-0.8
Financial difficulties in last 2 years	0.2	0.2	0.3	0.4	0.5
Fluid intelligence score	0.2	0.4	0.6	-0.5	-0.8
Hip circumference	0.2	0.9	1.3	-1.2	-0.7
Pulse rate	0.2	0.4	0.7	-0.1	0.8
Prospective memory result	0.2	0.2	0.3	0.4	0.6
Medication: Paracetamol	0.2	0.3	0.6	0.7	-0.1
Comparative body size at age 10	0.2	0.5	1.1	1.0	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.3	-0.5	-0.5
Medication: Seretide 50 evohaler	0.2	0.2	0.2	0.4	-0.5
Family relationship satisfaction	0.2	0.2	0.4	0.6	0.2
Knee pain experienced in last month	0.2	0.4	0.8	0.9	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.3	-0.4	0.6
Loneliness, isolation	0.2	0.2	0.5	-0.7	-0.2
Ever had bowel cancer screening	0.2	0.2	0.3	0.5	0.4
Diabetes diagnosed by doctor	0.2	0.4	0.5	-0.5	0.7
Wears glasses or contact lenses	0.2	0.2	0.4	-0.0	0.6
Eye problems/disorders: Glaucoma	0.2	0.2	0.3	-0.5	0.4
Medication: Paracetamol	0.2	0.4	0.8	-0.0	-0.9
Vascular/heart problems diagnosed by doctor	0.2	0.7	1.1	1.0	-0.5
Worry (Nagel 2018)	0.1	0.3	0.3	0.5	-0.5
Crohns Disease (2017)	0.1	0.1	0.2	0.1	-0.5
Irritable Bowel Disease (IBD)	0.1	0.3	0.4	0.6	0.5
Breast Cancer	0.1	0.2	0.3	0.2	0.5
Blood Platelet Count	0.1	0.6	1.3	1.1	0.0
Respiratory disease	0.1	0.3	0.6	0.8	-0.2
Lung FVC	0.1	0.3	0.4	0.6	-0.3
Hair Pigment	0.1	1.6	3.1	1.8	-0.5
Number of treatments/medications taken	0.1	0.2	0.5	-0.7	-0.1
Vitamin and mineral supplements	0.1	0.2	0.3	-0.2	-0.5
Diabetes (father)	0.1	0.1	0.1	-0.2	-0.4
Pack years adult smoking proportion	0.1	0.1	0.1	0.3	0.3
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	-0.5	-0.0
Medication: Levothyroxine sodium	0.1	0.2	0.2	0.4	0.5
High blood pressure (mother)	0.1	0.2	0.4	0.0	0.6
Waist circumference	0.1	0.4	0.6	0.8	0.3
Past tobacco smoking	0.1	0.1	0.2	-0.4	-0.2
Illnesses of siblings	0.1	0.1	0.1	0.1	-0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.3	0.1	0.6
Mouth/teeth dental problems: Dentures	0.1	0.2	0.4	-0.0	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.2	0.4	0.3
Arm fat mass (right)	0.1	0.3	0.4	0.6	-0.4
Tense / ‘highly strung’	0.1	0.1	0.1	0.4	-0.4
Headache pain in last month	0.1	0.1	0.2	0.1	0.5
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.5	0.1	-0.7
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.3	-0.6	0.3
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.2	-0.0	0.5
Migraine (self-reported)	0.1	0.1	0.1	-0.4	0.2
Medication: Ibuprofen	0.1	0.1	0.3	0.5	-0.1
Whole body fat mass	0.1	0.6	0.6	0.8	-0.8
Chest pain or discomfort	0.1	0.1	0.2	0.2	0.4
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.3	-0.5	-0.3
Back pain experienced in last month	0.1	0.1	0.2	0.3	0.5
Medication: Gliclazide	0.1	0.1	0.3	-0.5	0.1
Arm fat mass (left)	0.1	0.5	0.5	0.7	-0.7
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.1	0.4	-0.1
Alcohol drinker status: Never	0.1	0.1	0.2	0.5	0.0
Ever smoked	0.1	0.2	0.5	-0.0	0.7
Fasting Glucose	0.0	0.0	0.0	-0.1	0.2
Primary Biliary Cirrhosis	0.0	0.1	0.1	0.3	0.1
Ulcerative Colitis	0.0	0.0	0.0	-0.1	0.1
Blood Eosinophil Count	0.0	0.3	0.5	0.2	0.7
Blood White Count	0.0	0.2	0.3	-0.5	-0.1
Cardiovascular Disease	0.0	0.1	0.1	-0.4	0.2
Time employed in main current job	0.0	0.0	0.1	-0.3	-0.0
Exposure to tobacco smoke outside home	0.0	0.0	0.1	-0.1	0.2
Number of full brothers	0.0	0.1	0.1	-0.2	0.2
Suffer from ‘nerves’	0.0	0.1	0.1	0.3	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.1	0.1	0.4	-0.2
Illnesses of father: High blood pressure	0.0	0.0	0.0	-0.1	0.1
Irritability	0.0	0.0	0.0	0.0	0.0

Hub : Genes

MRPS11

Models

Trait associations