[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr5:129,797,129-132,900,729

Best TWAS P=4.6e-31 · Best GWAS P=2.51e-29 conditioned to 0.154

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
56	GTEx	Skin Sun Exposed Lower leg	PDLIM4	0.09	0.08	lasso	8	0.09	1.0e-07	11.24	-11.6	4.6e-31	-0.92	0.02	0.98	TRUE
12	GTEx	Artery Tibial	P4HA2	0.12	0.15	lasso	6	0.14	3.2e-11	11.22	11.5	1.4e-30	0.96	0.01	0.99	FALSE
61	GTEx	Testis	P4HA2	0.14	0.13	lasso	5	0.11	1.4e-05	11.24	11.4	3.8e-30	0.98	0.01	0.99	FALSE
11	GTEx	Artery Aorta	P4HA2-AS1	0.08	0.03	lasso	3	0.01	6.6e-02	11.14	11.3	9.4e-30	0.96	0.02	0.96	FALSE
15	GTEx	Artery Tibial	P4HA2-AS1	0.10	0.09	lasso	4	0.11	1.0e-08	11.21	11.3	1.8e-29	0.93	0.01	0.99	FALSE
9	GTEx	Artery Aorta	P4HA2	0.12	0.14	lasso	2	0.11	1.2e-06	11.24	11.3	2.1e-29	1.00	0.01	0.99	FALSE
87	YFS	Blood	SLC22A5	0.38	0.36	bslmm	430	0.37	3.0e-128	10.84	-11.2	2.8e-29	-0.88	0.26	0.74	FALSE
57	GTEx	Skin Sun Exposed Lower leg	SLC22A5	0.25	0.21	lasso	3	0.20	1.4e-16	10.93	-11.0	6.1e-28	-0.90	0.14	0.86	FALSE
58	GTEx	Spleen	SLC22A5	0.26	0.28	lasso	4	0.28	6.6e-08	10.84	10.8	2.3e-27	0.88	0.10	0.75	FALSE
72	GTEx	Whole Blood	SLC22A5	0.09	0.12	lasso	2	0.10	1.7e-09	10.84	-10.8	2.3e-27	-0.90	0.19	0.81	FALSE
78	METSIM	Adipose	SLC22A5	0.05	0.08	lasso	1	0.08	1.0e-11	10.84	-10.8	2.3e-27	-0.90	0.08	0.92	FALSE
37	GTEx	Esophagus Mucosa	P4HA2-AS1	0.09	0.06	lasso	6	0.08	5.4e-06	11.24	10.8	5.1e-27	0.97	0.01	0.99	FALSE
34	GTEx	Esophagus Mucosa	P4HA2	0.23	0.10	lasso	6	0.14	6.1e-10	11.24	10.8	5.3e-27	0.95	0.01	0.99	FALSE
47	GTEx	Nerve Tibial	P4HA2-AS1	0.14	0.05	lasso	8	0.08	3.8e-06	10.43	10.7	6.9e-27	0.88	0.02	0.98	FALSE
64	GTEx	Thyroid	P4HA2	0.08	0.07	enet	9	0.06	3.5e-05	11.22	10.7	8.8e-27	0.95	0.01	0.99	FALSE
115	The Cancer Genome Atlas	Thyroid Carcinoma	P4HA2	0.21	0.35	enet	10	0.35	4.7e-35	11.21	10.7	9.6e-27	0.95	0.00	1.00	FALSE
65	GTEx	Thyroid	PDLIM4	0.05	0.02	enet	5	0.01	3.1e-02	10.43	-10.6	4.9e-26	-0.88	0.05	0.90	FALSE
28	GTEx	Cells Transformed fibroblasts	SLC22A5	0.32	0.28	lasso	7	0.35	1.6e-27	-9.70	-10.5	5.2e-26	-0.84	0.55	0.45	FALSE
35	GTEx	Esophagus Mucosa	SLC22A5	0.16	0.16	enet	8	0.16	6.3e-11	10.84	-10.5	6.9e-26	-0.95	0.01	0.99	FALSE
73	GTEx	Whole Blood	AC034220.3	0.08	0.05	enet	31	0.06	4.0e-06	10.98	-10.5	8.0e-26	-0.79	0.06	0.93	FALSE
55	GTEx	Skin Not Sun Exposed Suprapubic	SLC22A5	0.13	0.05	lasso	8	0.05	8.3e-04	-9.29	-10.5	9.2e-26	-0.82	0.16	0.83	FALSE
44	GTEx	Muscle Skeletal	MIR3936	0.04	0.01	lasso	4	0.00	9.9e-02	-8.93	10.5	9.3e-26	0.82	0.10	0.61	FALSE
76	METSIM	Adipose	PDLIM4	0.05	0.04	lasso	4	0.02	2.8e-04	10.49	-10.5	1.0e-25	-0.83	0.76	0.19	FALSE
42	GTEx	Lung	SLC22A5	0.10	0.15	enet	11	0.13	3.4e-10	10.84	-10.4	3.4e-25	-0.93	0.07	0.93	FALSE
59	GTEx	Stomach	SLC22A5	0.09	0.04	lasso	4	0.01	9.0e-02	-9.73	-10.3	4.4e-25	-0.71	0.08	0.55	FALSE
114	The Cancer Genome Atlas	Thyroid Carcinoma	IRF1	0.05	0.02	blup	83	0.03	1.5e-03	9.39	10.3	5.3e-25	0.80	0.01	0.82	FALSE
45	GTEx	Nerve Tibial	P4HA2	0.19	0.12	enet	26	0.14	6.2e-10	-9.30	10.3	5.5e-25	0.85	0.01	0.99	FALSE
69	GTEx	Thyroid	P4HA2-AS1	0.08	0.06	enet	14	0.05	1.6e-04	11.22	10.3	6.7e-25	0.89	0.01	0.99	FALSE
96	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC22A5	0.06	0.05	blup	93	0.08	1.2e-09	-9.32	-10.3	8.2e-25	-0.76	0.14	0.86	FALSE
75	METSIM	Adipose	P4HA2	0.09	0.08	lasso	12	0.09	2.4e-13	11.21	10.3	1.1e-24	0.86	0.01	0.99	FALSE
94	The Cancer Genome Atlas	Colon Adenocarcinoma	SLC22A5	0.08	0.04	blup	92	0.07	1.2e-04	-9.70	-10.2	2.5e-24	-0.76	0.03	0.91	FALSE
43	GTEx	Muscle Skeletal	AC034220.3	0.27	0.23	lasso	9	0.24	9.1e-24	-9.43	10.2	3.2e-24	0.77	1.00	0.00	FALSE
106	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SLC22A5	0.05	0.03	blup	93	0.05	1.9e-06	-8.72	-10.0	9.7e-24	-0.74	0.04	0.96	FALSE
84	ROSMAP	Brain Pre-frontal Cortex	SLC22A4	0.03	0.05	lasso	2	0.04	1.2e-05	-10.25	-10.0	1.2e-23	-0.72	0.58	0.33	FALSE
39	GTEx	Heart Atrial Appendage	AC034220.3	0.16	0.09	enet	17	0.18	1.7e-08	-9.30	10.0	1.3e-23	0.77	0.59	0.41	FALSE
109	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC22A4	0.09	0.07	blup	108	0.09	3.0e-09	-9.30	-10.0	1.4e-23	-0.79	0.10	0.90	FALSE
10	GTEx	Artery Aorta	AC034220.3	0.08	0.06	lasso	3	0.05	1.1e-03	-9.34	10.0	1.5e-23	0.74	0.42	0.36	FALSE
103	The Cancer Genome Atlas	Lung Adenocarcinoma	SLC22A5	0.06	0.03	lasso	4	0.02	9.3e-04	-9.70	-9.8	6.9e-23	-0.69	0.05	0.79	FALSE
71	GTEx	Whole Blood	SLC22A4	0.07	0.05	enet	16	0.05	4.6e-05	-9.70	-9.8	1.2e-22	-0.72	0.11	0.81	FALSE
91	The Cancer Genome Atlas	Breast Invasive Carcinoma	SLC22A4	0.05	0.01	enet	7	0.02	1.6e-05	10.84	-9.8	1.2e-22	-0.82	0.01	0.98	FALSE
60	GTEx	Stomach	AC034220.3	0.17	0.15	enet	21	0.16	4.2e-08	-8.73	9.8	1.4e-22	0.68	1.00	0.00	FALSE
31	GTEx	Colon Transverse	AC034220.3	0.30	0.15	lasso	3	0.11	8.4e-06	-9.34	9.7	2.4e-22	0.73	0.92	0.04	FALSE
116	The Cancer Genome Atlas	Thyroid Carcinoma	SLC22A5	0.03	0.02	lasso	1	0.01	2.6e-02	-9.70	-9.7	3.0e-22	-0.72	0.02	0.68	FALSE
14	GTEx	Artery Tibial	SLC22A5	0.18	0.12	enet	8	0.12	2.5e-09	10.93	-9.7	3.1e-22	-0.83	0.12	0.88	FALSE
40	GTEx	Heart Left Ventricle	AC034220.3	0.25	0.22	lasso	6	0.25	8.6e-14	-9.34	9.7	3.3e-22	0.70	1.00	0.00	FALSE
92	The Cancer Genome Atlas	Breast Invasive Carcinoma	SLC22A5	0.05	0.07	enet	11	0.09	5.3e-17	-8.73	-9.6	5.5e-22	-0.68	1.00	0.00	FALSE
16	GTEx	Brain Caudate basal ganglia	AC034220.3	0.41	0.45	enet	19	0.46	8.8e-15	-9.43	9.6	7.6e-22	0.73	0.99	0.01	FALSE
19	GTEx	Brain Hippocampus	AC034220.3	0.21	0.15	lasso	14	0.18	5.8e-05	-9.38	9.6	7.9e-22	0.84	0.07	0.86	FALSE
83	ROSMAP	Brain Pre-frontal Cortex	PDLIM4	0.25	0.27	lasso	4	0.26	2.7e-33	-8.93	-9.6	9.3e-22	-0.73	1.00	0.00	FALSE
8	GTEx	Adrenal Gland	AC034220.3	0.12	0.11	lasso	16	0.08	7.7e-04	-9.29	9.6	1.1e-21	0.71	0.66	0.14	FALSE
32	GTEx	Esophagus Gastroesophageal Junction	SEPT8	0.22	0.08	lasso	12	0.10	2.2e-04	-8.94	9.6	1.1e-21	0.61	0.38	0.44	FALSE
36	GTEx	Esophagus Mucosa	AC034220.3	0.08	0.03	lasso	3	0.05	4.7e-04	-9.38	9.5	1.8e-21	0.71	0.95	0.03	FALSE
22	GTEx	Brain Nucleus accumbens basal ganglia	AC034220.3	0.24	0.24	enet	34	0.24	3.7e-07	-9.29	9.5	2.0e-21	0.71	0.88	0.06	FALSE
62	GTEx	Testis	PDLIM4	0.15	0.07	enet	8	0.05	2.5e-03	-9.38	9.5	2.0e-21	0.71	0.24	0.15	FALSE
108	The Cancer Genome Atlas	Prostate Adenocarcinoma	PDLIM4	0.32	0.36	enet	13	0.37	3.8e-40	-8.32	-9.5	2.5e-21	-0.74	1.00	0.00	FALSE
51	GTEx	Pituitary	AC034220.3	0.25	0.22	lasso	12	0.18	3.1e-05	-8.74	9.5	2.6e-21	0.66	0.66	0.10	FALSE
89	The Cancer Genome Atlas	Breast Invasive Carcinoma	P4HA2	0.03	0.02	blup	47	0.03	3.1e-06	11.21	9.4	4.0e-21	0.85	0.00	1.00	FALSE
7	GTEx	Adipose Visceral Omentum	AC034220.3	0.10	0.09	lasso	7	0.08	7.3e-05	-9.43	9.4	4.2e-21	0.71	0.40	0.34	FALSE
63	GTEx	Testis	AC034220.3	0.15	0.12	lasso	9	0.12	4.4e-06	-9.43	9.4	4.7e-21	0.71	0.87	0.04	FALSE
46	GTEx	Nerve Tibial	AC034220.3	0.15	0.11	lasso	5	0.10	1.9e-07	-9.29	9.3	1.2e-20	0.71	1.00	0.00	FALSE
5	GTEx	Adipose Subcutaneous	SLC22A5	0.05	0.04	lasso	4	0.04	4.2e-04	10.93	-9.3	1.3e-20	-0.83	0.05	0.93	FALSE
29	GTEx	Colon Sigmoid	AC034220.3	0.18	0.11	lasso	12	0.06	3.7e-03	-9.33	9.3	1.4e-20	0.70	0.25	0.13	FALSE
6	GTEx	Adipose Subcutaneous	AC034220.3	0.11	0.11	lasso	10	0.09	4.8e-08	-9.29	9.3	1.5e-20	0.71	1.00	0.00	FALSE
98	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC22A4	0.03	0.03	lasso	1	0.02	3.5e-03	-9.29	-9.3	1.5e-20	-0.71	0.36	0.24	FALSE
30	GTEx	Colon Transverse	SLC22A5	0.12	0.07	enet	8	0.07	2.5e-04	10.84	-9.3	2.0e-20	-0.81	0.13	0.77	FALSE
97	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PDLIM4	0.09	0.02	lasso	6	0.05	4.5e-06	-8.32	-9.2	2.7e-20	-0.67	0.12	0.77	FALSE
17	GTEx	Brain Cortex	AC034220.3	0.43	0.39	lasso	15	0.17	2.4e-05	-9.43	9.2	3.8e-20	0.70	0.93	0.07	FALSE
52	GTEx	Prostate	AC034220.3	0.38	0.37	lasso	5	0.37	3.0e-10	-9.34	9.1	7.4e-20	0.69	0.94	0.06	FALSE
3	CommonMind	Brain Pre-frontal Cortex	PDLIM4	0.11	0.18	lasso	5	0.18	8.0e-21	-8.85	-9.1	9.8e-20	-0.67	1.00	0.00	FALSE
53	GTEx	Skin Not Sun Exposed Suprapubic	PDLIM4	0.13	0.08	lasso	2	0.06	2.6e-04	10.84	-9.1	1.0e-19	-0.83	0.07	0.88	FALSE
26	GTEx	Cells EBV-transformed lymphocytes	SLC22A5	0.37	0.05	lasso	13	0.10	2.8e-04	10.84	-9.1	1.4e-19	-0.78	0.06	0.87	FALSE
99	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SLC22A4	0.04	0.03	blup	108	0.01	7.1e-02	-8.72	-9.0	2.0e-19	-0.62	0.12	0.13	FALSE
86	YFS	Blood	SLC22A4	0.10	0.12	enet	47	0.14	5.1e-42	-9.29	-9.0	2.8e-19	-0.71	1.00	0.00	FALSE
95	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC22A4	0.02	0.02	lasso	1	0.02	3.0e-03	-8.94	-8.9	3.9e-19	-0.58	0.12	0.53	FALSE
27	GTEx	Cells Transformed fibroblasts	PDLIM4	0.08	0.09	lasso	1	0.07	6.4e-06	-8.93	-8.9	4.3e-19	-0.67	0.81	0.05	FALSE
90	The Cancer Genome Atlas	Breast Invasive Carcinoma	PDLIM4	0.05	0.05	lasso	4	0.05	9.0e-11	-8.93	-8.8	8.6e-19	-0.69	0.99	0.01	FALSE
23	GTEx	Breast Mammary Tissue	SLC22A5	0.10	0.02	enet	16	0.06	4.5e-04	10.84	-8.7	3.4e-18	-0.71	0.20	0.71	FALSE
113	The Cancer Genome Atlas	Thyroid Carcinoma	C5orf56	0.06	0.04	blup	98	0.03	1.3e-03	-5.36	8.7	4.3e-18	0.54	0.79	0.11	FALSE
18	GTEx	Brain Frontal Cortex BA9	AC034220.3	0.31	0.20	lasso	14	0.21	3.3e-06	-9.38	8.6	9.9e-18	0.64	0.63	0.23	FALSE
48	GTEx	Ovary	AC004041.2	0.21	-0.01	lasso	2	-0.01	7.7e-01	-8.32	8.5	1.4e-17	0.62	0.06	0.26	FALSE
105	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SLC22A4	0.04	0.01	blup	111	0.03	3.0e-04	-4.92	-8.4	2.9e-17	-0.64	0.06	0.73	FALSE
38	GTEx	Esophagus Muscularis	AC034220.3	0.12	0.08	enet	20	0.07	3.8e-05	-9.34	8.3	6.8e-17	0.63	0.86	0.05	FALSE
101	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PDLIM4	0.08	0.03	blup	67	0.05	2.4e-03	-8.75	-8.2	2.3e-16	-0.61	0.04	0.36	FALSE
41	GTEx	Liver	AC034220.3	0.30	0.16	lasso	6	0.16	3.9e-05	-9.30	8.1	6.6e-16	0.56	0.59	0.05	FALSE
68	GTEx	Thyroid	AC034220.3	0.29	0.29	lasso	5	0.31	4.8e-24	-8.76	7.8	4.4e-15	0.46	1.00	0.00	FALSE
112	The Cancer Genome Atlas	Stomach Adenocarcinoma	SLC22A5	0.05	0.01	blup	92	0.02	1.1e-02	-6.10	-7.8	5.6e-15	-0.51	0.09	0.14	FALSE
54	GTEx	Skin Not Sun Exposed Suprapubic	SLC22A4	0.13	0.00	lasso	4	0.01	7.1e-02	-3.80	-7.8	9.4e-15	-0.65	0.15	0.08	FALSE
85	ROSMAP	Brain Pre-frontal Cortex	AC034220.3	0.04	0.02	blup	415	0.04	1.3e-05	-5.24	7.6	3.4e-14	0.62	0.94	0.03	FALSE
77	METSIM	Adipose	SLC22A4	0.05	0.02	lasso	3	0.03	8.4e-06	7.35	-7.5	4.7e-14	-0.50	0.94	0.02	FALSE
82	NTR	Blood	SLC22A4	0.02	0.00	blup	423	0.01	5.2e-04	7.35	-7.5	5.2e-14	-0.67	0.19	0.77	FALSE
110	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC22A5	0.12	0.05	lasso	4	0.08	1.8e-08	-4.96	-7.5	5.3e-14	-0.45	0.96	0.01	FALSE
88	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PDLIM4	0.05	0.01	enet	4	0.02	1.2e-02	-8.32	-7.4	1.4e-13	-0.53	0.08	0.07	FALSE
74	GTEx	Whole Blood	AC116366.6	0.05	0.04	lasso	17	0.03	5.7e-04	-5.08	7.0	1.9e-12	0.49	0.34	0.40	FALSE
13	GTEx	Artery Tibial	HINT1	0.11	0.04	enet	18	0.06	1.0e-05	-4.07	-7.0	3.3e-12	-0.58	0.10	0.83	FALSE
107	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC22A5	0.12	0.04	blup	92	0.07	2.2e-05	-9.70	-6.9	6.6e-12	-0.46	0.08	0.71	FALSE
93	The Cancer Genome Atlas	Colon Adenocarcinoma	PDLIM4	0.14	0.04	enet	9	0.09	6.8e-06	-8.52	-6.8	7.6e-12	-0.63	0.45	0.25	FALSE
67	GTEx	Thyroid	SLC22A5	0.17	0.07	lasso	5	0.13	4.8e-10	-0.47	-6.7	1.6e-11	-0.68	0.13	0.87	FALSE
25	GTEx	Breast Mammary Tissue (Female)	SLC22A5	0.04	-0.01	lasso	3	0.01	1.3e-01	-3.08	-6.6	3.2e-11	-0.55	0.05	0.14	FALSE
2	CommonMind	Brain Pre-frontal Cortex	LOC553103	0.05	0.02	bslmm	433	0.03	3.2e-04	-8.72	6.6	4.7e-11	0.42	0.81	0.01	FALSE
66	GTEx	Thyroid	SLC22A4	0.06	0.02	lasso	4	0.02	2.3e-02	-8.73	6.5	5.9e-11	0.44	0.38	0.10	FALSE
49	GTEx	Pancreas	P4HA2	0.22	0.21	lasso	13	0.20	5.3e-09	-4.63	6.5	6.9e-11	0.60	0.78	0.20	FALSE
111	The Cancer Genome Atlas	Rectum Adenocarcinoma	SLC22A5	0.27	0.21	lasso	12	0.24	2.0e-06	-8.74	-6.5	8.0e-11	-0.42	0.48	0.26	FALSE
21	GTEx	Brain Nucleus accumbens basal ganglia	SLC22A5	0.15	0.00	enet	24	0.05	1.4e-02	-9.49	6.4	1.6e-10	0.45	0.11	0.11	FALSE
81	NTR	Blood	IRF1	0.03	0.02	blup	424	0.01	5.7e-05	-5.08	6.0	1.4e-09	0.50	1.00	0.00	FALSE
104	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C5orf56	0.07	0.01	blup	98	0.03	3.2e-04	-5.28	6.0	1.7e-09	0.36	0.25	0.08	FALSE
20	GTEx	Brain Hypothalamus	AC034220.3	0.38	0.14	enet	33	0.28	3.2e-07	-5.73	6.0	2.1e-09	0.41	0.52	0.10	FALSE
102	The Cancer Genome Atlas	Lung Adenocarcinoma	LYRM7	0.03	0.01	enet	10	0.02	7.5e-04	-3.73	6.0	2.4e-09	0.40	0.01	0.91	FALSE
50	GTEx	Pancreas	P4HA2-AS1	0.16	0.16	lasso	5	0.16	3.2e-07	-4.63	5.9	3.5e-09	0.52	0.60	0.30	FALSE
80	NTR	Blood	C5orf56	0.01	0.01	blup	439	0.01	1.7e-03	-5.79	-5.9	4.0e-09	-0.45	0.20	0.28	FALSE
70	GTEx	Uterus	P4HA2	0.58	-0.01	lasso	5	0.02	1.6e-01	-5.05	5.9	4.3e-09	0.41	0.04	0.40	FALSE
79	NTR	Blood	ACSL6	0.01	0.00	bslmm	399	0.00	2.8e-02	-4.22	-5.8	6.7e-09	-0.50	0.19	0.24	FALSE
4	GTEx	Adipose Subcutaneous	HINT1	0.10	0.07	enet	16	0.06	8.8e-06	-4.40	-5.5	3.3e-08	-0.40	0.80	0.02	FALSE
33	GTEx	Esophagus Gastroesophageal Junction	UQCRQ	0.21	0.01	enet	30	0.04	2.0e-02	-5.80	-5.5	3.8e-08	-0.36	0.09	0.14	FALSE
100	The Cancer Genome Atlas	Brain Lower Grade Glioma	C5orf56	0.03	0.01	blup	98	0.02	4.2e-03	-5.27	5.5	3.9e-08	0.42	0.14	0.09	FALSE
1	CommonMind	Brain Pre-frontal Cortex	KIF3A	0.05	0.01	bslmm	433	0.01	1.3e-02	1.21	-5.4	7.0e-08	-0.31	0.08	0.07	FALSE
24	GTEx	Breast Mammary Tissue (Male)	SLC22A5	0.09	0.08	lasso	4	0.06	1.8e-02	-5.02	-5.3	1.5e-07	-0.38	0.05	0.21	FALSE