[Hub]/) : Traits : Sitting height :

chr19:41,165,252-43,237,764

Best TWAS P=1.09e-18 · Best GWAS P=7.51e-19 conditioned to 0.025

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ATP5SL 0.34 0.48 bslmm 365 0.48 1.5e-65 8.6 -8.5 2.1e-17 -0.94 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex BCKDHA 0.12 0.08 lasso 6 0.10 8.9e-13 8.7 -7.5 7.8e-14 -0.91 0.02 0.98 FALSE
3 GTEx Artery Aorta ATP5SL 0.14 0.00 lasso 2 0.01 1.6e-01 8.5 -8.5 2.8e-17 -0.93 0.03 0.49 FALSE
4 GTEx Artery Aorta B3GNT8 0.14 0.09 lasso 2 0.08 2.6e-05 8.6 7.9 3.9e-15 0.92 0.03 0.97 FALSE
5 GTEx Artery Aorta CTC-435M10.6 0.16 0.14 lasso 3 0.13 1.3e-07 8.7 8.6 6.5e-18 0.95 0.03 0.97 FALSE
6 GTEx Brain Cerebellar Hemisphere B3GNT8 0.38 0.30 lasso 5 0.23 1.1e-06 8.6 8.6 5.2e-18 0.93 0.02 0.98 FALSE
7 GTEx Brain Cerebellar Hemisphere CTC-435M10.6 0.29 0.20 lasso 4 0.18 2.6e-05 8.6 8.7 2.3e-18 0.96 0.02 0.96 FALSE
8 GTEx Brain Cerebellum B3GNT8 0.28 0.23 lasso 5 0.21 9.2e-07 8.6 8.6 7.5e-18 0.95 0.03 0.97 FALSE
9 GTEx Brain Cerebellum CTC-435M10.6 0.18 0.01 lasso 4 0.03 5.1e-02 8.6 8.6 9.4e-18 0.84 0.03 0.80 FALSE
10 GTEx Brain Frontal Cortex BA9 ATP5SL 0.28 0.15 lasso 3 0.10 1.0e-03 8.5 -8.4 3.7e-17 -0.94 0.03 0.92 FALSE
11 GTEx Cells Transformed fibroblasts TMEM91 0.08 0.00 enet 31 0.01 7.4e-02 3.3 5.4 6.3e-08 0.52 0.04 0.73 FALSE
12 GTEx Cells Transformed fibroblasts B3GNT8 0.10 0.02 lasso 2 0.03 2.0e-03 8.5 8.4 4.8e-17 0.93 0.05 0.95 FALSE
13 GTEx Cells Transformed fibroblasts CTC-435M10.6 0.18 0.16 lasso 2 0.15 4.2e-11 8.5 8.3 1.4e-16 0.91 0.03 0.97 FALSE
14 GTEx Colon Transverse B3GNT8 0.21 0.17 lasso 4 0.18 6.7e-09 8.5 8.3 8.0e-17 0.93 0.05 0.95 FALSE
15 GTEx Colon Transverse CTC-435M10.6 0.26 0.19 enet 19 0.22 5.8e-11 8.4 7.9 1.9e-15 0.86 0.04 0.96 FALSE
16 GTEx Esophagus Gastroesophageal Junction CTC-435M10.6 0.23 0.10 enet 17 0.10 1.7e-04 8.6 6.8 1.1e-11 0.84 0.03 0.93 FALSE
17 GTEx Esophagus Muscularis B3GNT8 0.14 0.10 lasso 2 0.16 7.5e-10 -4.4 6.6 3.1e-11 0.85 0.04 0.96 FALSE
18 GTEx Esophagus Muscularis CTC-435M10.6 0.12 0.12 lasso 2 0.10 1.4e-06 8.3 8.2 1.7e-16 0.91 0.04 0.96 FALSE
19 GTEx Heart Atrial Appendage TMEM91 0.12 0.05 lasso 4 0.08 1.7e-04 5.7 5.6 1.6e-08 0.55 0.05 0.70 FALSE
20 GTEx Heart Left Ventricle CTC-435M10.6 0.18 0.02 lasso 4 0.06 4.8e-04 8.4 6.4 1.1e-10 0.80 0.02 0.97 FALSE
21 GTEx Lung CTC-435M10.6 0.13 0.11 lasso 3 0.10 3.3e-08 8.5 8.5 2.4e-17 0.93 0.04 0.96 FALSE
22 GTEx Muscle Skeletal EXOSC5 0.07 0.03 enet 6 0.03 4.1e-04 8.6 8.6 7.4e-18 0.95 0.01 0.99 FALSE
23 GTEx Nerve Tibial B9D2 0.13 0.08 lasso 4 0.06 2.9e-05 5.1 6.0 1.7e-09 0.68 0.08 0.82 FALSE
24 GTEx Nerve Tibial B3GNT8 0.22 0.17 enet 12 0.20 6.6e-14 8.3 7.6 3.3e-14 0.91 0.04 0.96 FALSE
25 GTEx Nerve Tibial CTC-435M10.6 0.18 0.15 lasso 6 0.14 5.5e-10 8.3 8.6 6.7e-18 0.94 0.02 0.98 FALSE
26 GTEx Skin Sun Exposed Lower leg B3GNT8 0.11 0.04 lasso 6 0.05 1.1e-04 -4.4 7.0 2.2e-12 0.87 0.03 0.97 FALSE
27 GTEx Stomach B3GNT8 0.22 0.14 lasso 7 0.12 1.4e-06 8.5 8.4 3.4e-17 0.93 0.02 0.98 FALSE
28 GTEx Stomach CTC-435M10.6 0.23 0.14 lasso 11 0.13 1.0e-06 8.3 7.7 1.1e-14 0.91 0.02 0.98 FALSE
29 GTEx Testis EXOSC5 0.31 0.33 enet 10 0.33 1.8e-15 8.4 8.5 1.2e-17 0.95 0.04 0.96 FALSE
30 GTEx Testis GRIK5 0.41 0.24 lasso 10 0.24 7.9e-11 -5.8 6.0 1.6e-09 0.02 0.01 0.99 TRUE
31 GTEx Thyroid EXOSC5 0.14 0.08 lasso 5 0.05 8.4e-05 8.6 8.4 6.3e-17 0.92 0.04 0.94 FALSE
32 GTEx Thyroid B3GNT8 0.09 0.04 enet 17 0.03 1.4e-03 8.6 6.8 1.1e-11 0.82 0.01 0.97 FALSE
33 GTEx Thyroid CTC-435M10.6 0.07 0.03 lasso 2 0.04 7.9e-04 8.6 6.8 7.8e-12 0.83 0.02 0.97 FALSE
34 YFS Blood ATP5SL 0.06 0.02 lasso 12 0.03 1.1e-09 8.9 8.3 1.3e-16 0.85 0.01 0.99 FALSE
35 YFS Blood BCKDHA 0.08 0.05 enet 27 0.06 1.9e-18 8.7 -7.4 1.4e-13 -0.84 0.02 0.98 FALSE
36 The Cancer Genome Atlas Bladder Urothelial Carcinoma B3GNT8 0.03 0.04 blup 20 0.04 3.2e-04 8.5 8.4 3.8e-17 0.94 0.01 0.96 FALSE
37 The Cancer Genome Atlas Bladder Urothelial Carcinoma BCKDHA 0.02 0.02 lasso 2 0.02 1.5e-02 8.6 -8.6 7.7e-18 -0.94 0.01 0.83 FALSE
38 The Cancer Genome Atlas Breast Invasive Carcinoma B3GNT8 0.04 0.07 blup 20 0.07 1.2e-13 8.4 8.3 1.6e-16 0.94 0.03 0.97 FALSE
39 The Cancer Genome Atlas Colon Adenocarcinoma B3GNT8 0.09 0.13 blup 20 0.11 5.2e-07 8.3 8.1 7.2e-16 0.93 0.02 0.98 FALSE
40 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BCKDHA 0.03 0.03 enet 4 0.03 1.8e-04 -4.4 -5.4 8.5e-08 -0.72 0.03 0.78 FALSE
41 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DEDD2 0.02 0.02 lasso 1 0.01 3.1e-02 -5.8 5.8 8.1e-09 0.01 0.01 0.95 FALSE
42 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ATP5SL 0.04 0.03 enet 12 0.03 1.6e-04 8.8 -7.9 2.1e-15 -0.88 0.00 0.99 FALSE
43 The Cancer Genome Atlas Brain Lower Grade Glioma ATP5SL 0.02 0.03 enet 4 0.02 7.0e-04 8.6 -8.6 1.0e-17 -0.94 0.02 0.90 FALSE
44 The Cancer Genome Atlas Brain Lower Grade Glioma EXOSC5 0.04 0.03 lasso 2 0.02 5.8e-03 8.6 8.1 3.7e-16 0.91 0.01 0.70 FALSE
45 The Cancer Genome Atlas Brain Lower Grade Glioma RABAC1 0.01 0.01 enet 2 0.01 1.8e-02 -4.8 5.3 9.5e-08 0.03 0.00 0.44 FALSE
46 The Cancer Genome Atlas Pancreatic Adenocarcinoma B3GNT8 0.15 0.12 blup 20 0.12 1.3e-05 -4.4 6.7 2.5e-11 0.86 0.03 0.93 FALSE
47 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ATP5SL 0.23 0.05 blup 18 0.05 4.5e-03 8.8 -8.8 1.1e-18 -0.86 0.01 0.86 TRUE
48 The Cancer Genome Atlas Prostate Adenocarcinoma ATP5SL 0.03 0.03 blup 18 0.03 4.1e-04 8.8 -8.7 3.8e-18 -0.94 0.01 0.94 FALSE
49 The Cancer Genome Atlas Rectum Adenocarcinoma B3GNT8 0.39 0.08 blup 20 0.07 1.1e-02 8.6 7.9 2.1e-15 0.81 0.00 0.30 FALSE
50 The Cancer Genome Atlas Rectum Adenocarcinoma GSK3A 0.15 0.10 lasso 7 0.09 4.0e-03 -5.7 -5.7 9.3e-09 -0.01 0.00 0.55 FALSE
51 The Cancer Genome Atlas Thyroid Carcinoma ATP5SL 0.02 0.02 blup 18 0.02 3.5e-03 8.8 -8.4 3.1e-17 -0.94 0.01 0.82 FALSE
52 The Cancer Genome Atlas Thyroid Carcinoma B3GNT8 0.10 0.12 lasso 3 0.11 1.3e-10 8.6 7.8 4.6e-15 0.92 0.02 0.98 FALSE
53 The Cancer Genome Atlas Thyroid Carcinoma EXOSC5 0.02 0.01 blup 31 0.03 4.5e-04 8.5 7.7 1.1e-14 0.92 0.01 0.94 FALSE