[Hub]/) : Traits : Mean time to correctly identify matches :

chr11:45,258,966-48,285,906

Best TWAS P=4.64e-13 · Best GWAS P=2.7e-11 conditioned to 0.0323

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LRP4 0.04 0.05 lasso 4 0.04 6.6e-06 5.4 5.6 1.9e-08 0.66 0.78 0.20 FALSE
2 GTEx Adipose Subcutaneous ARHGAP1 0.08 0.03 lasso 6 0.05 3.4e-05 5.4 -6.3 2.9e-10 -0.84 0.25 0.69 FALSE
3 GTEx Breast Mammary Tissue ARHGAP1 0.05 0.00 enet 14 0.01 1.3e-01 6.2 -5.4 6.3e-08 -0.79 0.08 0.46 FALSE
4 GTEx Cells EBV-transformed lymphocytes LRP4 0.68 0.00 lasso 10 0.00 5.0e-01 -3.4 -5.2 2.6e-07 -0.46 0.03 0.12 FALSE
5 GTEx Esophagus Mucosa ARFGAP2 0.05 0.06 lasso 4 0.05 4.4e-04 5.1 5.2 1.9e-07 0.72 0.30 0.11 FALSE
6 GTEx Esophagus Muscularis CKAP5 0.05 0.03 lasso 4 0.04 3.3e-03 5.1 6.0 2.2e-09 0.69 0.38 0.13 FALSE
7 GTEx Esophagus Muscularis ARHGAP1 0.07 0.08 lasso 3 0.07 6.1e-05 5.1 -5.5 3.2e-08 -0.79 0.39 0.56 FALSE
8 GTEx Esophagus Muscularis ATG13 0.12 0.08 enet 16 0.04 1.2e-03 6.3 -5.2 1.6e-07 -0.63 0.04 0.95 FALSE
9 GTEx Liver ZNF408 0.10 0.09 lasso 3 0.08 3.5e-03 6.4 -6.9 4.8e-12 -0.95 0.05 0.56 FALSE
10 GTEx Liver ARHGAP1 0.12 0.05 enet 4 0.05 1.5e-02 5.9 -7.2 4.6e-13 -0.71 0.05 0.46 TRUE
11 GTEx Muscle Skeletal ARHGAP1 0.03 0.05 lasso 2 0.04 1.2e-04 6.2 -6.2 7.4e-10 -0.93 0.04 0.93 FALSE
12 GTEx Nerve Tibial ARHGAP1 0.10 0.03 enet 14 0.05 9.7e-05 6.4 -5.9 2.8e-09 -0.88 0.09 0.90 FALSE
13 GTEx Nerve Tibial LRP4-AS1 0.23 0.16 enet 15 0.24 1.1e-16 -3.4 5.2 2.1e-07 0.60 0.98 0.02 FALSE
14 GTEx Ovary ARHGAP1 0.25 0.09 lasso 16 0.18 3.8e-05 6.1 -7.0 1.8e-12 -0.84 0.09 0.71 FALSE
15 GTEx Pancreas LRP4 0.11 0.10 enet 16 0.14 1.8e-06 5.1 -5.2 1.9e-07 -0.76 0.57 0.39 FALSE
16 GTEx Pancreas ARHGAP1 0.09 0.06 lasso 7 0.04 6.4e-03 6.2 -6.3 2.7e-10 -0.92 0.06 0.74 FALSE
17 GTEx Pancreas LRP4-AS1 0.10 0.08 lasso 6 0.12 1.4e-05 5.1 -5.4 7.8e-08 -0.76 0.40 0.49 FALSE
18 GTEx Prostate CELF1 0.17 0.16 lasso 2 0.12 6.2e-04 5.4 5.4 5.4e-08 0.60 0.03 0.84 FALSE
19 GTEx Prostate ZNF408 0.19 0.10 lasso 2 0.10 1.6e-03 5.3 -5.3 1.0e-07 -0.65 0.14 0.11 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic ARHGAP1 0.06 0.01 lasso 9 0.00 2.8e-01 5.3 -6.2 4.2e-10 -0.84 0.10 0.46 FALSE
21 GTEx Skin Not Sun Exposed Suprapubic ATG13 0.12 0.07 lasso 5 0.06 3.3e-04 5.8 -6.0 1.5e-09 -0.64 0.06 0.94 FALSE
22 GTEx Skin Sun Exposed Lower leg DDB2 0.08 0.10 lasso 4 0.10 5.8e-09 5.1 5.7 1.0e-08 0.70 0.28 0.72 FALSE
23 GTEx Skin Sun Exposed Lower leg ARHGAP1 0.08 0.01 lasso 5 0.02 1.4e-02 6.2 -5.8 6.5e-09 -0.87 0.13 0.55 FALSE
24 GTEx Skin Sun Exposed Lower leg ATG13 0.08 0.05 lasso 4 0.05 5.1e-05 6.4 -5.6 1.6e-08 -0.66 0.05 0.95 FALSE
25 GTEx Spleen LRP4 0.15 0.14 lasso 5 0.12 6.5e-04 6.0 -6.0 2.5e-09 -0.46 0.12 0.32 FALSE
26 GTEx Thyroid C11orf49 0.09 0.05 lasso 3 0.04 3.0e-04 6.0 -5.9 2.8e-09 -0.46 0.33 0.63 FALSE
27 GTEx Uterus C11orf49 0.24 0.24 lasso 13 0.24 1.3e-05 5.8 -5.8 5.2e-09 -0.47 0.11 0.23 FALSE
28 METSIM Adipose DDB2 0.03 0.03 lasso 2 0.02 1.9e-04 5.4 -5.4 5.7e-08 -0.55 0.19 0.77 FALSE
29 ROSMAP Brain Pre-frontal Cortex C11orf49 0.02 0.02 blup 322 0.02 3.3e-04 5.2 5.3 1.4e-07 0.73 0.82 0.11 FALSE
30 ROSMAP Brain Pre-frontal Cortex PACSIN3 0.11 0.00 bslmm 292 0.04 1.8e-06 -3.6 6.5 5.9e-11 0.46 0.08 0.55 FALSE
31 YFS Blood PHF21A 0.01 0.01 bslmm 385 0.00 1.9e-02 4.2 5.5 4.6e-08 0.33 0.60 0.13 FALSE
32 The Cancer Genome Atlas Breast Invasive Carcinoma ARHGAP1 0.02 0.01 blup 26 0.02 2.7e-04 6.2 -6.8 1.3e-11 -0.88 0.01 0.82 FALSE
33 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MDK 0.03 0.02 lasso 3 0.02 2.3e-03 6.3 -5.5 3.4e-08 -0.61 0.01 0.97 FALSE
34 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CKAP5 0.09 0.01 blup 58 0.04 2.9e-03 5.2 6.6 4.2e-11 0.63 0.04 0.78 FALSE
35 The Cancer Genome Atlas Pancreatic Adenocarcinoma ARHGAP1 0.11 0.01 blup 26 0.03 2.7e-02 5.3 -6.1 1.4e-09 -0.85 0.01 0.54 FALSE
36 The Cancer Genome Atlas Prostate Adenocarcinoma ZNF408 0.02 0.00 blup 27 0.02 4.3e-03 5.0 -5.8 8.2e-09 -0.87 0.01 0.60 FALSE
37 The Cancer Genome Atlas Stomach Adenocarcinoma HARBI1 0.05 0.02 blup 12 0.02 1.5e-02 5.9 5.8 5.7e-09 0.68 0.01 0.75 FALSE
38 The Cancer Genome Atlas Thyroid Carcinoma PACSIN3 0.09 0.01 enet 5 0.03 3.1e-04 5.5 5.3 1.5e-07 0.54 0.02 0.82 FALSE