[Hub]/) : Traits : Forced vital capacity (FVC), Best measure : ← →

chr20:46,551,079-48,603,940

Best TWAS P=1.93e-19 · Best GWAS P=1.04e-22 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	METSIM	Adipose	ARFGEF2	0.04	0.03	lasso	12	0.02	9.8e-05	9.8	-9.0	1.9e-19	-0.98	0.02	0.98	TRUE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	ARFGEF2	0.05	0.04	lasso	5	0.05	3.2e-06	9.6	-9.0	3.3e-19	-0.94	0.00	1.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ARFGEF2	0.09	0.05	lasso	8	0.10	9.2e-13	9.6	-8.9	3.6e-19	-0.82	0.00	1.00	FALSE
19	NTR	Blood	SNORD12B	0.03	0.05	lasso	8	0.05	1.9e-14	8.1	-8.8	1.3e-18	-0.96	0.05	0.95	FALSE
16	GTEx	Testis	ARFGEF2	0.20	0.20	lasso	7	0.24	5.4e-11	6.4	-8.3	7.4e-17	-0.91	0.02	0.98	FALSE
27	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C20orf199	0.05	0.06	lasso	4	0.06	1.0e-04	8.1	8.1	5.9e-16	0.92	0.00	0.96	FALSE
4	GTEx	Cells Transformed fibroblasts	STAU1	0.08	0.03	lasso	6	0.02	2.3e-02	6.4	7.5	4.5e-14	0.85	0.03	0.93	FALSE
10	GTEx	Esophagus Mucosa	ZFAS1	0.15	0.01	enet	16	0.01	8.9e-02	8.1	7.5	8.7e-14	0.69	0.06	0.78	FALSE
8	GTEx	Colon Transverse	ARFGEF2	0.11	0.07	enet	12	0.09	2.9e-05	-3.4	-7.4	1.1e-13	-0.78	0.06	0.91	FALSE
7	GTEx	Colon Sigmoid	CSE1L	0.18	0.12	lasso	11	0.09	4.4e-04	7.3	-7.4	1.5e-13	-0.80	0.12	0.83	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	CSE1L	0.04	0.02	enet	16	0.02	2.8e-03	6.6	-7.3	2.8e-13	-0.72	0.14	0.85	FALSE
14	GTEx	Skin Sun Exposed Lower leg	CSE1L	0.08	0.03	lasso	2	0.03	9.5e-04	7.5	-7.2	4.4e-13	-0.81	0.40	0.29	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	ZFAS1	0.16	0.04	enet	19	0.07	1.0e-04	6.2	7.2	5.8e-13	0.69	0.03	0.92	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CSE1L	0.05	0.07	blup	50	0.07	3.2e-08	7.2	-7.1	1.6e-12	-0.80	0.39	0.61	FALSE
30	The Cancer Genome Atlas	Thyroid Carcinoma	DDX27	0.08	0.05	lasso	3	0.05	1.9e-05	8.1	7.0	2.5e-12	0.85	0.06	0.90	FALSE
15	GTEx	Skin Sun Exposed Lower leg	ZFAS1	0.07	0.03	enet	14	0.05	5.8e-05	8.1	6.8	7.2e-12	0.77	0.18	0.76	FALSE
9	GTEx	Esophagus Mucosa	CSE1L	0.09	0.06	lasso	4	0.06	6.9e-05	7.3	-6.8	1.2e-11	-0.80	0.24	0.70	FALSE
11	GTEx	Lung	CSE1L	0.10	0.09	lasso	5	0.08	6.6e-07	6.4	-6.8	1.5e-11	-0.73	0.51	0.48	FALSE
6	GTEx	Colon Sigmoid	ARFGEF2	0.15	0.12	lasso	1	0.07	2.3e-03	6.6	-6.6	4.6e-11	-0.60	0.05	0.61	FALSE
18	NTR	Blood	NCRNA00275	0.07	0.06	lasso	4	0.08	9.7e-25	-2.7	-6.5	7.3e-11	-0.53	1.00	0.00	FALSE
23	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CSE1L	0.03	0.05	lasso	1	0.03	9.3e-05	6.4	-6.4	1.7e-10	-0.75	0.30	0.61	FALSE
12	GTEx	Muscle Skeletal	PREX1	0.14	0.09	enet	23	0.13	2.5e-12	7.5	6.1	8.4e-10	0.51	0.81	0.19	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	STAU1	0.01	0.01	blup	54	0.01	6.1e-03	-5.2	-6.1	1.1e-09	-0.46	0.03	0.13	FALSE
3	GTEx	Artery Tibial	CSE1L	0.12	0.03	lasso	6	0.04	3.8e-04	-3.4	-6.1	1.3e-09	-0.68	0.22	0.77	FALSE
21	YFS	Blood	CSE1L	0.06	0.05	enet	21	0.06	2.0e-19	-3.5	-5.9	2.8e-09	-0.60	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CSE1L	0.08	0.07	bslmm	503	0.05	1.7e-06	-3.4	-5.8	8.4e-09	-0.58	0.88	0.12	FALSE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C20orf199	0.04	0.00	enet	8	0.02	6.4e-03	3.6	5.6	2.5e-08	0.62	0.01	0.51	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	ARFGEF2	0.06	0.01	blup	79	0.03	4.2e-04	-3.6	-5.5	4.8e-08	-0.42	0.75	0.05	FALSE
5	GTEx	Cells Transformed fibroblasts	ZFAS1	0.06	0.05	enet	5	0.03	2.6e-03	-5.2	5.2	2.1e-07	0.29	0.41	0.26	FALSE
28	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CSE1L	0.13	0.03	blup	50	0.07	1.4e-03	6.4	-5.2	2.4e-07	-0.60	0.03	0.26	FALSE