[Hub]/) : Traits : Whole body fat mass : ← →

chr11:64,915,042-68,077,666

Best TWAS P=5.71e-12 · Best GWAS P=2.64e-15 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
48	GTEx	Nerve Tibial	RAD9A	0.53	0.24	lasso	10	0.23	5.6e-16	-6.9	-6.9	5.7e-12	0.15	0.00	1.00	TRUE
1	CommonMind	Brain Pre-frontal Cortex	FIBP	0.08	0.11	enet	20	0.12	8.1e-14	4.6	6.4	1.5e-10	-0.34	1.00	0.00	TRUE
39	GTEx	Esophagus Muscularis	CTD-3074O7.5	0.22	0.02	enet	17	0.09	3.7e-06	-2.2	6.3	2.3e-10	-0.50	0.30	0.46	TRUE
94	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RPS6KB2	0.12	0.06	blup	35	0.05	5.4e-03	-5.3	6.1	9.0e-10	-0.27	0.01	0.80	TRUE
61	GTEx	Uterus	PACS1	0.21	-0.01	enet	21	0.05	3.6e-02	4.2	-6.1	1.2e-09	0.42	0.07	0.30	TRUE
78	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CNIH2	0.03	0.00	enet	4	0.02	6.4e-03	-4.8	5.7	1.0e-08	-0.58	0.06	0.12	TRUE
41	GTEx	Heart Atrial Appendage	RPS6KB2	0.16	0.09	lasso	9	0.07	3.5e-04	-5.1	5.3	1.2e-07	-0.27	0.52	0.07	TRUE
22	GTEx	Brain Hippocampus	PTPRCAP	0.16	0.13	lasso	4	0.18	6.2e-05	-5.3	5.2	1.5e-07	-0.25	0.15	0.06	TRUE
71	ROSMAP	Brain Pre-frontal Cortex	RAD9A	0.34	0.17	enet	21	0.20	1.1e-25	-6.9	-5.2	2.0e-07	0.09	0.00	1.00	TRUE
11	GTEx	Artery Tibial	RAD9A	0.39	0.26	lasso	2	0.24	3.5e-19	-6.9	-6.9	6.7e-12	0.16	0.00	1.00	FALSE
57	GTEx	Testis	RAD9A	0.72	0.50	lasso	4	0.49	1.1e-24	-6.9	-6.8	7.2e-12	0.15	0.00	1.00	FALSE
4	GTEx	Adipose Subcutaneous	RAD9A	0.43	0.22	lasso	6	0.23	7.1e-19	-6.9	-6.8	1.2e-11	0.15	0.00	1.00	FALSE
69	ROSMAP	Brain Pre-frontal Cortex	CDK2AP2	0.03	0.02	enet	11	0.03	1.6e-04	-4.7	6.7	2.0e-11	-0.21	0.27	0.60	FALSE
37	GTEx	Esophagus Muscularis	RAD9A	0.25	0.26	lasso	2	0.26	6.2e-16	-6.9	-6.6	5.1e-11	0.13	0.00	1.00	FALSE
93	The Cancer Genome Atlas	Stomach Adenocarcinoma	SNX32	0.12	0.13	blup	60	0.13	1.2e-09	4.6	6.2	7.7e-10	-0.16	0.91	0.09	FALSE
42	GTEx	Heart Atrial Appendage	PTPRCAP	0.14	0.11	lasso	10	0.09	5.1e-05	-5.1	6.0	2.0e-09	-0.27	0.65	0.05	FALSE
44	GTEx	Liver	CDK2AP2	0.30	-0.01	lasso	7	-0.01	4.9e-01	-3.7	-5.9	2.9e-09	0.23	0.02	0.47	FALSE
30	GTEx	Breast Mammary Tissue (Male)	GSTP1	0.11	-0.01	lasso	2	-0.01	7.7e-01	-4.7	5.9	3.2e-09	-0.19	0.02	0.42	FALSE
54	GTEx	Skin Not Sun Exposed Suprapubic	AP003419.16	0.15	0.08	lasso	5	0.08	6.2e-05	-5.3	5.8	5.0e-09	-0.26	0.48	0.06	FALSE
15	GTEx	Brain Cerebellar Hemisphere	GSTP1	0.25	0.15	enet	16	0.20	8.7e-06	-4.4	5.8	6.5e-09	-0.22	0.52	0.34	FALSE
77	The Cancer Genome Atlas	Glioblastoma Multiforme	CTSW	0.16	0.18	enet	16	0.19	2.3e-06	4.9	-5.8	6.5e-09	0.23	0.31	0.34	FALSE
18	GTEx	Brain Cerebellum	NDUFV1	0.19	0.01	enet	29	0.05	1.7e-02	4.1	-5.7	1.1e-08	0.18	0.07	0.06	FALSE
86	The Cancer Genome Atlas	Lung Adenocarcinoma	SNX32	0.14	0.09	blup	60	0.13	8.8e-15	5.5	5.7	1.1e-08	-0.16	0.63	0.37	FALSE
88	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SNX32	0.08	0.10	blup	60	0.11	6.0e-08	5.5	5.6	2.7e-08	-0.19	0.68	0.31	FALSE
81	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PTPRCAP	0.05	0.04	enet	3	0.03	1.2e-02	-5.4	5.5	2.9e-08	-0.26	0.01	0.81	FALSE
89	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SNX32	0.30	0.19	lasso	1	0.14	3.9e-06	5.5	5.5	3.3e-08	-0.12	0.31	0.65	FALSE
38	GTEx	Esophagus Muscularis	YIF1A	0.11	0.05	enet	11	0.04	2.4e-03	4.5	-5.5	3.4e-08	0.57	0.83	0.15	FALSE
62	GTEx	Uterus	PTPRCAP	0.28	0.15	lasso	5	0.15	5.5e-04	-5.4	5.5	3.7e-08	-0.29	0.14	0.08	FALSE
9	GTEx	Adrenal Gland	CTSW	0.13	0.08	lasso	12	0.06	3.0e-03	4.9	-5.5	3.8e-08	0.22	0.31	0.18	FALSE
84	The Cancer Genome Atlas	Lung Adenocarcinoma	FIBP	0.02	0.01	blup	45	0.02	1.3e-03	4.9	5.5	4.0e-08	-0.25	0.04	0.62	FALSE
83	The Cancer Genome Atlas	Brain Lower Grade Glioma	FIBP	0.04	0.04	lasso	3	0.04	1.2e-05	5.5	5.5	4.3e-08	-0.13	0.15	0.84	FALSE
68	METSIM	Adipose	PTPRCAP	0.03	0.02	lasso	4	0.02	1.7e-04	-5.4	5.5	4.5e-08	-0.29	0.72	0.04	FALSE
21	GTEx	Brain Frontal Cortex BA9	PTPRCAP	0.21	0.11	enet	15	0.15	9.6e-05	-5.1	5.5	4.8e-08	-0.29	0.53	0.06	FALSE
51	GTEx	Pancreas	AP003419.16	0.11	0.05	enet	14	0.07	8.4e-04	-5.1	5.4	5.2e-08	-0.28	0.52	0.05	FALSE
63	GTEx	Vagina	PTPRCAP	0.33	0.05	enet	8	0.06	2.0e-02	-5.1	5.5	5.2e-08	-0.29	0.09	0.06	FALSE
6	GTEx	Adipose Visceral Omentum	RPS6KB2	0.08	0.03	lasso	8	0.04	2.9e-03	-5.2	5.4	5.5e-08	-0.26	0.51	0.06	FALSE
53	GTEx	Skin Not Sun Exposed Suprapubic	PTPRCAP	0.22	0.14	enet	19	0.15	1.8e-08	-5.0	5.4	6.0e-08	-0.28	0.96	0.04	FALSE
60	GTEx	Thyroid	PACS1	0.09	0.04	enet	16	0.09	2.8e-07	-7.8	-5.4	6.2e-08	0.79	0.02	0.98	FALSE
3	CommonMind	Brain Pre-frontal Cortex	SNX32	0.46	0.36	lasso	8	0.39	1.9e-50	5.5	5.4	6.3e-08	-0.16	1.00	0.00	FALSE
8	GTEx	Adipose Visceral Omentum	AP003419.16	0.09	0.05	enet	8	0.04	4.6e-03	-5.2	5.4	6.9e-08	-0.28	0.34	0.11	FALSE
96	The Cancer Genome Atlas	Thyroid Carcinoma	SNX32	0.23	0.26	lasso	7	0.25	6.4e-24	5.5	5.4	7.0e-08	-0.14	0.21	0.79	FALSE
65	METSIM	Adipose	GSTP1	0.05	0.05	lasso	6	0.04	9.3e-07	-5.3	5.4	7.1e-08	-0.22	0.96	0.04	FALSE
64	METSIM	Adipose	FIBP	0.05	0.02	blup	344	0.02	1.0e-03	4.6	5.4	7.2e-08	-0.39	0.96	0.01	FALSE
34	GTEx	Esophagus Mucosa	RPS6KB2	0.12	0.09	lasso	3	0.11	1.1e-07	-5.1	5.4	7.4e-08	-0.26	0.93	0.04	FALSE
85	The Cancer Genome Atlas	Lung Adenocarcinoma	RPS6KB2	0.05	0.07	lasso	4	0.06	6.2e-08	-5.3	5.4	7.6e-08	-0.28	0.01	0.99	FALSE
33	GTEx	Cells Transformed fibroblasts	AP003419.16	0.21	0.22	lasso	6	0.21	1.6e-15	-5.1	5.4	8.3e-08	-0.27	0.97	0.03	FALSE
35	GTEx	Esophagus Mucosa	AP003419.16	0.18	0.15	lasso	3	0.18	7.8e-12	-5.1	5.4	8.3e-08	-0.27	0.97	0.03	FALSE
14	GTEx	Brain Caudate basal ganglia	PTPRCAP	0.23	0.19	lasso	4	0.21	1.0e-06	-5.1	5.3	8.6e-08	-0.27	0.74	0.08	FALSE
75	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPS6KB2	0.05	0.06	lasso	3	0.06	1.1e-12	-5.3	5.3	8.6e-08	-0.28	0.00	0.99	FALSE
25	GTEx	Brain Nucleus accumbens basal ganglia	GSTP1	0.23	0.11	lasso	5	0.14	1.8e-04	-5.1	5.3	8.7e-08	-0.22	0.47	0.06	FALSE
58	GTEx	Testis	RPS6KB2	0.20	0.16	lasso	11	0.16	8.3e-08	-5.1	5.3	8.7e-08	-0.28	0.95	0.05	FALSE
16	GTEx	Brain Cerebellar Hemisphere	PTPRCAP	0.39	0.43	lasso	8	0.47	7.7e-14	-5.3	5.3	9.4e-08	-0.28	0.94	0.05	FALSE
17	GTEx	Brain Cerebellar Hemisphere	AP003419.16	0.20	0.01	lasso	4	0.05	1.7e-02	-5.4	5.3	1.0e-07	-0.20	0.04	0.17	FALSE
74	The Cancer Genome Atlas	Breast Invasive Carcinoma	PACS1	0.02	0.02	blup	77	0.02	8.5e-05	4.8	-5.3	1.0e-07	0.52	0.50	0.11	FALSE
29	GTEx	Breast Mammary Tissue	AP003419.16	0.19	0.06	lasso	5	0.05	2.3e-03	-5.4	5.3	1.1e-07	-0.29	0.16	0.19	FALSE
76	The Cancer Genome Atlas	Breast Invasive Carcinoma	SNX32	0.15	0.17	blup	60	0.17	2.9e-34	5.5	5.3	1.1e-07	-0.16	0.24	0.76	FALSE
40	GTEx	Heart Atrial Appendage	KLC2	0.10	0.04	lasso	8	0.09	1.1e-04	4.8	-5.3	1.2e-07	0.56	0.27	0.42	FALSE
56	GTEx	Testis	AIP	0.11	0.14	lasso	2	0.11	1.5e-05	-5.2	5.3	1.2e-07	-0.26	0.83	0.04	FALSE
70	ROSMAP	Brain Pre-frontal Cortex	CTSW	0.06	0.03	bslmm	328	0.03	3.6e-05	4.9	-5.3	1.2e-07	0.12	0.60	0.02	FALSE
24	GTEx	Brain Hypothalamus	PTPRCAP	0.17	0.21	lasso	4	0.19	3.1e-05	-5.1	5.3	1.3e-07	-0.28	0.31	0.10	FALSE
23	GTEx	Brain Hypothalamus	GSTP1	0.29	0.28	lasso	3	0.26	9.3e-07	-5.3	5.3	1.4e-07	-0.20	0.51	0.07	FALSE
31	GTEx	Cells EBV-transformed lymphocytes	FIBP	0.40	0.21	enet	26	0.29	4.3e-10	4.6	5.3	1.4e-07	-0.17	0.99	0.00	FALSE
55	GTEx	Stomach	AP003419.16	0.12	0.11	lasso	4	0.08	1.4e-04	-5.2	5.3	1.4e-07	-0.28	0.40	0.05	FALSE
19	GTEx	Brain Cerebellum	PTPRCAP	0.39	0.48	lasso	7	0.46	3.8e-15	-5.2	5.3	1.5e-07	-0.28	0.94	0.06	FALSE
28	GTEx	Breast Mammary Tissue	PTPRCAP	0.18	0.26	lasso	3	0.24	2.0e-12	-5.2	5.2	1.5e-07	-0.27	0.98	0.02	FALSE
52	GTEx	Pituitary	PTPRCAP	0.24	0.33	lasso	6	0.26	4.0e-07	-5.1	5.2	1.5e-07	-0.28	0.86	0.05	FALSE
97	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	CTSW	0.24	0.21	enet	21	0.24	2.9e-07	4.6	-5.2	1.5e-07	0.17	0.62	0.34	FALSE
7	GTEx	Adipose Visceral Omentum	PTPRCAP	0.10	0.08	enet	7	0.06	4.8e-04	-5.0	5.2	1.6e-07	-0.29	0.64	0.03	FALSE
67	METSIM	Adipose	PACS1	0.15	0.17	enet	24	0.17	1.2e-24	4.8	-5.2	1.6e-07	0.44	1.00	0.00	FALSE
92	The Cancer Genome Atlas	Soft Tissue Sarcoma	SNX32	0.08	0.08	lasso	2	0.10	1.5e-06	4.6	5.2	1.6e-07	-0.21	0.81	0.10	FALSE
20	GTEx	Brain Cortex	PACS1	0.19	0.11	lasso	9	0.08	2.9e-03	4.7	-5.2	1.7e-07	0.60	0.26	0.30	FALSE
59	GTEx	Testis	AP003419.16	0.22	0.18	lasso	8	0.18	1.3e-08	-5.1	5.2	1.7e-07	-0.28	0.95	0.04	FALSE
45	GTEx	Muscle Skeletal	GSTP1	0.07	0.08	lasso	9	0.07	1.0e-07	-4.9	5.2	1.8e-07	-0.23	0.96	0.03	FALSE
50	GTEx	Ovary	PTPRCAP	0.35	0.28	enet	13	0.26	5.3e-07	-5.1	5.2	1.8e-07	-0.28	0.76	0.04	FALSE
32	GTEx	Cells Transformed fibroblasts	RPS6KB2	0.19	0.28	lasso	3	0.27	1.7e-20	-5.1	5.2	1.9e-07	-0.28	0.97	0.03	FALSE
66	METSIM	Adipose	KLC2	0.06	0.06	blup	323	0.05	1.2e-08	4.8	-5.2	1.9e-07	0.53	1.00	0.00	FALSE
80	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	GSTP1	0.04	0.05	lasso	5	0.04	1.7e-03	-5.1	5.2	1.9e-07	-0.18	0.01	0.92	FALSE
13	GTEx	Artery Tibial	AP003419.16	0.11	0.13	lasso	2	0.12	2.2e-09	-5.2	5.2	2.1e-07	-0.28	0.96	0.04	FALSE
43	GTEx	Heart Atrial Appendage	RP11-867G23.1	0.19	0.13	lasso	5	0.11	1.6e-05	-5.5	-5.2	2.1e-07	0.66	0.11	0.81	FALSE
79	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SNX32	0.15	0.11	blup	60	0.15	6.0e-17	5.5	5.2	2.1e-07	-0.14	0.23	0.77	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PTPRCAP	0.05	0.07	enet	12	0.07	6.0e-09	-5.0	5.2	2.2e-07	-0.28	0.97	0.03	FALSE
10	GTEx	Artery Aorta	GSTP1	0.10	0.07	enet	14	0.10	5.4e-06	-5.3	5.2	2.2e-07	-0.20	0.70	0.05	FALSE
90	The Cancer Genome Atlas	Prostate Adenocarcinoma	RPS6KB2	0.09	0.13	lasso	6	0.13	7.1e-14	-5.1	5.2	2.2e-07	-0.27	0.02	0.98	FALSE
47	GTEx	Muscle Skeletal	AP003419.16	0.19	0.21	lasso	2	0.20	1.4e-19	-5.2	5.2	2.3e-07	-0.28	0.97	0.03	FALSE
72	ROSMAP	Brain Pre-frontal Cortex	SNX32	0.50	0.53	lasso	13	0.54	1.1e-81	5.5	5.2	2.3e-07	-0.13	1.00	0.00	FALSE
82	The Cancer Genome Atlas	Brain Lower Grade Glioma	EFEMP2	0.01	0.00	blup	45	0.01	3.0e-02	3.6	5.2	2.3e-07	-0.23	0.04	0.11	FALSE
49	GTEx	Nerve Tibial	PTPRCAP	0.33	0.38	enet	14	0.47	2.1e-37	-5.0	5.2	2.4e-07	-0.28	0.98	0.02	FALSE
12	GTEx	Artery Tibial	RPS6KB2	0.10	0.10	lasso	1	0.10	5.9e-08	-5.2	5.2	2.5e-07	-0.28	0.96	0.04	FALSE
46	GTEx	Muscle Skeletal	PTPRCAP	0.09	0.08	lasso	6	0.09	2.6e-09	-5.1	5.2	2.5e-07	-0.26	0.98	0.02	FALSE
87	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RPS6KB2	0.05	0.05	lasso	6	0.04	1.2e-05	-5.1	5.2	2.5e-07	-0.28	0.02	0.98	FALSE
26	GTEx	Brain Nucleus accumbens basal ganglia	PTPRCAP	0.35	0.36	lasso	7	0.38	2.7e-11	-5.1	5.2	2.6e-07	-0.28	0.96	0.03	FALSE
27	GTEx	Brain Putamen basal ganglia	PTPRCAP	0.24	0.26	lasso	4	0.22	6.2e-06	-5.1	5.1	2.7e-07	-0.28	0.61	0.04	FALSE
95	The Cancer Genome Atlas	Thyroid Carcinoma	NDUFV1	0.03	0.00	blup	43	0.01	6.7e-02	-4.6	-5.2	2.7e-07	0.20	0.01	0.84	FALSE
73	ROSMAP	Brain Pre-frontal Cortex	PTPRCAP	0.31	0.47	enet	14	0.47	2.7e-68	-5.1	5.1	2.8e-07	-0.28	0.98	0.02	FALSE
36	GTEx	Esophagus Muscularis	GSTP1	0.16	0.18	lasso	3	0.16	9.1e-10	-4.9	5.1	2.9e-07	-0.19	0.99	0.01	FALSE
5	GTEx	Adipose Subcutaneous	AP003419.16	0.05	0.08	lasso	1	0.07	1.7e-06	-5.1	5.1	3.0e-07	-0.28	0.84	0.03	FALSE
91	The Cancer Genome Atlas	Soft Tissue Sarcoma	RPS6KB2	0.05	0.04	lasso	2	0.04	2.1e-03	-5.1	5.1	3.0e-07	-0.28	0.02	0.93	FALSE