[Hub]/) : Traits : Basal metabolic rate :

chr17:27,200,734-30,884,028

Best TWAS P=4.16e-31 · Best GWAS P=1.68e-37 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NF1 0.06 0.01 blup 410 0.04 1.1e-05 7.54 6.7 2.5e-11 -0.20 0.95 0.00 FALSE
2 GTEx Adipose Visceral Omentum TEFM 0.12 0.02 lasso 14 0.05 1.0e-03 1.79 -6.5 7.8e-11 0.21 0.08 0.09 FALSE
3 GTEx Artery Aorta ABHD15 0.20 0.03 enet 36 0.06 2.9e-04 -5.32 -7.8 8.1e-15 0.08 0.03 0.56 TRUE
4 GTEx Artery Aorta TEFM 0.13 0.02 enet 34 0.03 5.8e-03 1.81 -7.3 2.7e-13 0.57 0.15 0.78 FALSE
5 GTEx Artery Aorta CRLF3 0.12 0.03 enet 33 0.06 3.8e-04 1.83 -8.1 4.1e-16 0.53 0.25 0.70 TRUE
6 GTEx Artery Tibial RP11-848P1.7 0.54 0.00 lasso 10 0.02 7.3e-03 -7.40 -11.6 4.2e-31 0.47 0.02 0.06 TRUE
7 GTEx Brain Cerebellar Hemisphere CRLF3 0.38 0.35 enet 26 0.35 6.0e-10 3.07 -6.5 7.9e-11 0.32 0.97 0.01 FALSE
8 GTEx Brain Cerebellum CRLF3 0.52 0.12 lasso 27 0.20 1.3e-06 -10.84 -9.9 4.0e-23 0.56 0.09 0.74 FALSE
9 GTEx Breast Mammary Tissue CRLF3 0.10 0.10 lasso 3 0.05 9.6e-04 3.69 -6.0 2.5e-09 0.31 0.09 0.62 FALSE
10 GTEx Cells EBV-transformed lymphocytes EVI2A 0.13 0.03 lasso 4 0.01 1.5e-01 7.54 -7.9 2.1e-15 0.17 0.16 0.04 FALSE
11 GTEx Cells Transformed fibroblasts OMG 0.06 0.02 lasso 2 0.01 2.5e-02 7.52 7.6 2.9e-14 -0.22 0.14 0.07 FALSE
12 GTEx Cells Transformed fibroblasts TEFM 0.15 0.09 lasso 16 0.09 6.1e-07 1.79 -5.1 3.1e-07 0.45 0.96 0.04 FALSE
13 GTEx Colon Transverse CRLF3 0.16 0.07 lasso 6 0.05 1.5e-03 1.83 -5.8 4.8e-09 0.42 0.15 0.64 FALSE
14 GTEx Esophagus Mucosa ABHD15 0.21 0.13 lasso 1 0.10 1.7e-07 -5.32 -5.3 1.0e-07 0.00 0.09 0.91 FALSE
15 GTEx Esophagus Muscularis BLMH 0.15 0.02 lasso 8 0.01 1.0e-01 -3.57 5.8 5.0e-09 -0.13 0.04 0.46 TRUE
16 GTEx Esophagus Muscularis CRLF3 0.17 0.12 lasso 6 0.18 5.1e-11 3.07 -7.9 2.3e-15 0.46 0.94 0.05 FALSE
17 GTEx Muscle Skeletal TP53I13 0.08 0.02 lasso 4 0.02 2.2e-03 -5.32 6.2 6.0e-10 -0.08 0.08 0.28 FALSE
18 GTEx Nerve Tibial TEFM 0.16 0.01 lasso 4 0.06 2.7e-05 1.83 -5.5 4.7e-08 0.43 0.26 0.59 FALSE
19 GTEx Nerve Tibial CRLF3 0.38 0.16 lasso 14 0.19 3.0e-13 3.20 -6.8 1.4e-11 0.38 1.00 0.00 FALSE
20 GTEx Nerve Tibial SUZ12P 0.25 0.34 enet 44 0.35 1.1e-25 3.20 -5.2 2.1e-07 0.29 1.00 0.00 FALSE
21 GTEx Ovary CRLF3 0.21 0.14 lasso 4 0.11 1.0e-03 3.07 -6.8 1.1e-11 0.40 0.06 0.58 FALSE
22 GTEx Pituitary SUZ12P 0.29 0.23 lasso 9 0.32 6.0e-09 3.06 -6.7 2.6e-11 0.40 0.86 0.07 FALSE
23 GTEx Spleen EVI2A 0.22 0.12 lasso 4 0.07 8.3e-03 7.59 -7.4 1.4e-13 0.17 0.11 0.05 FALSE
24 GTEx Spleen OMG 0.41 0.10 enet 26 0.08 4.5e-03 7.52 6.9 5.4e-12 -0.23 0.64 0.03 FALSE
25 GTEx Testis CRLF3 0.26 0.19 enet 23 0.17 3.8e-08 3.24 -6.1 9.8e-10 0.38 0.99 0.00 FALSE
26 GTEx Thyroid COPRS 0.17 0.00 enet 43 0.01 1.2e-01 0.53 -5.2 1.8e-07 0.13 0.04 0.19 FALSE
27 GTEx Thyroid CRLF3 0.10 0.04 enet 35 0.08 1.1e-06 3.20 -6.5 7.2e-11 0.38 0.91 0.05 FALSE
28 GTEx Whole Blood EVI2A 0.07 0.04 lasso 4 0.04 2.6e-04 7.47 -7.7 1.3e-14 0.14 0.89 0.00 FALSE
29 METSIM Adipose CTD-2349P21.5 0.02 0.00 bslmm 252 0.01 3.0e-03 -9.06 -7.5 7.0e-14 0.33 0.04 0.31 FALSE
30 METSIM Adipose NF1 0.04 0.00 blup 396 0.01 5.5e-03 7.93 7.9 2.6e-15 -0.30 0.80 0.02 FALSE
31 METSIM Adipose TEFM 0.08 0.06 blup 246 0.06 8.8e-10 -12.80 -8.6 9.9e-18 0.57 0.00 1.00 TRUE
32 YFS Blood CPD 0.18 0.13 enet 38 0.14 8.5e-42 3.36 -5.2 2.2e-07 0.27 1.00 0.00 FALSE
33 YFS Blood EVI2A 0.03 0.05 lasso 4 0.04 1.0e-13 7.59 -7.6 3.2e-14 0.10 1.00 0.00 FALSE
34 YFS Blood EVI2B 0.01 0.00 blup 339 0.00 6.4e-02 -0.25 7.1 1.0e-12 -0.26 0.07 0.02 FALSE
35 The Cancer Genome Atlas Bladder Urothelial Carcinoma EVI2A 0.03 0.03 blup 37 0.03 2.3e-03 7.48 -7.4 1.2e-13 0.10 0.03 0.66 FALSE
36 The Cancer Genome Atlas Bladder Urothelial Carcinoma OMG 0.02 0.02 blup 31 0.02 3.2e-03 7.47 -7.9 2.1e-15 0.15 0.03 0.79 FALSE
37 The Cancer Genome Atlas Breast Invasive Carcinoma ABHD15 0.04 0.03 lasso 2 0.02 1.4e-05 -5.32 -5.3 1.1e-07 -0.01 0.09 0.81 TRUE
38 The Cancer Genome Atlas Breast Invasive Carcinoma EVI2A 0.03 0.03 blup 38 0.03 6.9e-07 7.41 -7.8 9.3e-15 0.12 0.05 0.95 FALSE
39 The Cancer Genome Atlas Breast Invasive Carcinoma GOSR1 0.02 0.01 enet 4 0.01 1.7e-02 -7.44 7.5 4.6e-14 -0.27 0.01 0.83 FALSE
40 The Cancer Genome Atlas Breast Invasive Carcinoma OMG 0.03 0.04 lasso 1 0.04 1.1e-08 7.64 -7.6 2.2e-14 0.23 0.01 0.99 FALSE
41 The Cancer Genome Atlas Colon Adenocarcinoma LRRC37B2 0.09 0.00 enet 11 0.03 7.3e-03 4.22 -6.9 4.5e-12 0.47 0.01 0.26 FALSE
42 The Cancer Genome Atlas Esophageal Carcinoma OMG 0.09 0.09 blup 31 0.11 2.0e-04 7.71 -8.0 1.1e-15 0.18 0.02 0.92 FALSE
43 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EVI2A 0.04 0.00 blup 37 0.01 1.1e-02 7.41 -5.7 9.4e-09 0.00 0.02 0.34 FALSE
44 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma OMG 0.02 0.02 blup 31 0.03 6.9e-04 7.68 -8.0 1.8e-15 0.17 0.02 0.89 FALSE
45 The Cancer Genome Atlas Brain Lower Grade Glioma CRLF3 0.07 0.06 blup 37 0.08 2.8e-09 3.22 -5.3 1.1e-07 0.37 1.00 0.00 FALSE
46 The Cancer Genome Atlas Brain Lower Grade Glioma EVI2A 0.03 0.03 blup 38 0.04 3.0e-05 7.43 -7.9 2.1e-15 0.16 0.04 0.96 FALSE
47 The Cancer Genome Atlas Liver Hepatocellular Carcinoma NF1 0.04 0.03 blup 111 0.03 1.3e-02 7.71 7.8 4.2e-15 -0.19 0.05 0.65 FALSE
48 The Cancer Genome Atlas Lung Adenocarcinoma C17orf42 0.04 0.02 enet 5 0.04 5.4e-05 -1.28 -5.5 2.8e-08 0.46 0.17 0.46 FALSE
49 The Cancer Genome Atlas Lung Adenocarcinoma EVI2A 0.04 0.06 blup 38 0.06 3.0e-07 7.36 -7.8 4.3e-15 0.15 0.07 0.93 FALSE
50 The Cancer Genome Atlas Lung Adenocarcinoma OMG 0.05 0.03 lasso 5 0.04 3.6e-05 7.40 -6.8 1.3e-11 0.10 0.05 0.88 FALSE
51 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EVI2A 0.03 0.03 lasso 1 0.02 2.4e-03 7.28 -7.3 3.4e-13 0.10 0.03 0.51 FALSE
52 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma GOSR1 0.15 0.00 blup 56 0.04 1.1e-03 -3.87 7.0 2.0e-12 -0.35 0.04 0.19 FALSE
53 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma OMG 0.05 0.03 blup 32 0.03 5.6e-03 7.52 -7.3 2.4e-13 0.25 0.01 0.76 FALSE
54 The Cancer Genome Atlas Pancreatic Adenocarcinoma CRLF3 0.07 0.06 blup 40 0.06 2.0e-03 3.22 -5.2 1.8e-07 0.32 0.09 0.20 FALSE
55 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CRLF3 0.28 0.13 blup 40 0.11 3.1e-05 2.73 -5.6 2.3e-08 0.28 0.33 0.06 FALSE
56 The Cancer Genome Atlas Prostate Adenocarcinoma ATAD5 0.14 0.08 enet 11 0.09 4.1e-10 1.78 5.4 7.1e-08 -0.41 0.99 0.01 FALSE
57 The Cancer Genome Atlas Prostate Adenocarcinoma EVI2A 0.08 0.12 lasso 3 0.12 1.3e-12 7.93 -7.9 3.6e-15 0.12 0.03 0.97 FALSE
58 The Cancer Genome Atlas Stomach Adenocarcinoma EVI2A 0.05 0.03 enet 7 0.04 4.8e-04 3.55 -6.1 1.0e-09 0.13 0.04 0.65 FALSE
59 The Cancer Genome Atlas Stomach Adenocarcinoma SUZ12P 0.05 0.05 blup 29 0.04 5.1e-04 3.69 -6.2 6.8e-10 0.32 0.16 0.16 TRUE
60 The Cancer Genome Atlas Thyroid Carcinoma OMG 0.02 0.01 blup 32 0.02 4.8e-03 7.52 -8.0 1.7e-15 0.18 0.02 0.86 FALSE