TWAS hub - ZNF559

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.7780	0.0230	0.0e+00	0.555	0.451	0.549	0.540	0.553	2.2e-81	8.1e-61	3.9e-80	5.0e-78	5.0e-81
2	ROSMAP	Brain Pre-frontal Cortex	0.3485	0.0740	9.4e-11	0.191	0.087	0.200	0.209	0.211	6.2e-24	3.0e-11	3.5e-25	2.4e-26	1.2e-26
3	YFS	Blood	0.6254	0.0397	0.0e+00	0.004	0.106	0.169	0.052	0.068	1.2e-02	1.1e-32	5.5e-53	1.1e-16	2.3e-21
4	TCGA	Bladder Urothelial Carcinoma	0.3440	0.1130	6.1e-05	0.078	0.046	0.074	NA	0.067	3.8e-07	9.5e-05	7.8e-07	NA	2.5e-06
5	TCGA	Breast Invasive Carcinoma	0.1713	0.0610	1.7e-08	0.044	0.037	0.053	NA	0.048	1.9e-09	4.5e-08	4.5e-11	NA	3.2e-10
6	TCGA	Glioblastoma Multiforme	0.4490	0.1580	1.2e-03	0.016	0.015	0.071	NA	0.040	1.0e-01	1.1e-01	3.6e-03	NA	2.3e-02
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.1973	0.0879	7.8e-04	0.043	0.046	0.052	NA	0.052	1.3e-05	6.4e-06	1.5e-06	NA	1.7e-06
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.4094	0.1034	1.4e-07	0.097	0.079	0.078	NA	0.094	5.5e-11	3.1e-09	4.4e-09	NA	9.3e-11
9	TCGA	Kidney Renal Papillary Cell Carcinoma	0.3820	0.1380	4.3e-03	0.124	0.038	0.082	NA	0.114	1.4e-07	3.0e-03	1.9e-05	NA	4.6e-07
10	TCGA	Brain Lower Grade Glioma	0.3434	0.0917	1.6e-08	0.114	0.095	0.109	NA	0.111	6.9e-13	6.3e-11	2.5e-12	NA	1.6e-12
11	TCGA	Lung Adenocarcinoma	0.2734	0.0829	5.8e-09	0.087	0.092	0.112	NA	0.106	2.5e-10	6.5e-11	5.1e-13	NA	2.4e-12
12	TCGA	Lung Squamous Cell Carcinoma	0.0978	0.0521	1.7e-04	0.002	0.027	0.021	NA	0.014	1.8e-01	4.2e-04	1.7e-03	NA	8.3e-03
13	TCGA	Pancreatic Adenocarcinoma	0.6520	0.0930	1.4e-09	0.277	0.246	0.256	NA	0.270	4.7e-12	1.0e-10	3.7e-11	NA	9.1e-12
14	TCGA	Pheochromocytoma and Paraganglioma	0.5500	0.1250	8.4e-04	0.168	0.035	0.153	NA	0.159	3.4e-07	1.6e-02	1.2e-06	NA	7.2e-07
15	TCGA	Prostate Adenocarcinoma	0.5461	0.0815	0.0e+00	0.227	0.215	0.223	NA	0.227	2.0e-23	3.8e-22	5.6e-23	NA	2.1e-23
16	TCGA	Stomach Adenocarcinoma	0.3410	0.1370	5.8e-03	0.066	0.041	0.037	NA	0.057	1.7e-05	6.2e-04	1.1e-03	NA	5.7e-05
17	TCGA	Thyroid Carcinoma	0.5520	0.1100	2.8e-16	0.169	0.172	0.174	NA	0.198	3.0e-16	1.8e-16	1.0e-16	NA	6.1e-19

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Heart attack	8.7	11.1	14.4	-3.8	-3.5	-3.4	-2.7	-3.1	-2.5	-3.5	-3.6	-3.8	-3.7	-2.9	-1.4	-3.5	-3.6	-3.7	-3.8	-3.3
Heart attack/myocardial infarction (self-reported)	8.1	10.4	13.3	-3.6	-3.4	-3.3	-2.8	-3.0	-2.6	-3.4	-3.5	-3.6	-3.6	-2.8	-1.2	-3.4	-3.5	-3.6	-3.6	-3.2
Illnesses of mother	6.4	7.9	9.5	3.1	3.0	1.9	2.4	3.0	2.6	2.6	2.9	2.9	2.9	2.9	3.1	3.0	2.8	2.9	2.9	2.8
Heart disease (mother)	4.3	5.2	7.7	-2.3	-2.7	-1.5	-2.8	-2.4	-2.3	-1.5	-2.3	-2.3	-2.3	-2.5	-1.8	-2.5	-2.4	-2.4	-2.2	-2.4
Wears glasses or contact lenses	3.0	3.4	4.8	-2.0	-2.2	0.5	-1.0	-2.0	-1.4	-2.1	-1.9	-2.1	-2.0	-1.8	0.2	-2.0	-2.1	-2.1	-2.1	-2.2
Ulcerative Colitis (UC)	2.8	5.2	6.9	-2.4	-2.6	-1.2	-2.4	-2.6	-2.1	-1.8	-2.2	-2.3	-2.3	-2.2	-2.2	-2.3	-2.4	-2.4	-2.3	-2.5
Emphysema/chronic bronchitis	2.8	3.1	4.7	2.1	1.4	1.5	2.1	1.3	0.7	1.8	2.2	2.1	2.1	1.6	1.0	1.8	2.1	2.0	2.1	1.4
Medication: Lansoprazole	2.7	3.1	6.4	2.0	1.8	1.0	1.7	1.7	1.1	1.5	1.8	1.9	1.8	1.4	2.5	1.8	2.0	1.9	1.9	1.6
Number of treatments/medications taken	2.6	4.7	6.3	-2.4	-2.4	-0.9	-1.4	-2.3	-2.1	-2.5	-2.3	-2.4	-2.3	-2.2	-0.5	-2.3	-2.2	-2.4	-2.4	-2.5
Had major operations	2.5	2.9	5.3	-1.6	-2.0	-1.9	-1.1	-1.8	-2.3	-2.1	-1.5	-1.6	-1.6	-2.0	-0.6	-1.6	-1.3	-1.7	-1.6	-2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.7	4.3	-2.0	-2.0	-2.0	-1.7	-2.1	-1.9	-1.6	-2.0	-1.9	-2.0	-2.0	-1.6	-2.0	-1.7	-2.0	-1.9	-1.9
Medication: Amlodipine	2.4	3.4	6.5	-1.8	-2.4	0.7	-0.8	-2.2	-2.1	-2.5	-1.7	-1.8	-1.8	-2.0	0.3	-1.7	-1.8	-1.9	-1.9	-2.3
Medication: Omeprazole	2.4	2.9	4.0	-1.8	-1.9	-0.1	-2.0	-1.6	-1.7	-1.7	-1.8	-1.9	-1.8	-1.6	-0.2	-1.9	-1.8	-1.9	-1.9	-1.8
Time employed in main current job	2.3	2.6	3.6	-1.7	-1.8	-0.8	-1.3	-1.9	-1.5	-1.9	-1.8	-1.8	-1.8	-1.7	-0.6	-1.5	-1.7	-1.8	-1.8	-1.6
Lung cancer (father)	2.3	2.6	4.3	-1.8	-1.8	-0.1	-1.9	-1.6	-1.1	-0.9	-1.6	-1.9	-1.8	-1.3	-0.9	-2.1	-2.0	-1.9	-1.8	-1.7
Length of working week for main job	2.3	2.6	4.7	1.4	2.0	1.6	1.2	2.2	1.8	1.1	1.3	1.5	1.5	1.9	0.5	1.7	1.6	1.7	1.5	2.1
Tense / ‘highly strung’	2.3	3.8	7.1	-2.0	-1.9	-1.5	-2.7	-2.0	-1.3	-1.3	-2.0	-2.1	-2.1	-2.1	-0.4	-2.1	-2.2	-2.1	-2.1	-2.1
Medication: Simvastatin	2.2	3.2	7.2	-1.7	-2.2	-0.9	-0.3	-2.1	-2.2	-2.7	-1.6	-1.7	-1.7	-2.0	0.1	-1.7	-1.6	-1.8	-1.8	-2.4
Pulse wave reflection index	2.2	2.7	5.6	-1.8	-1.4	-2.2	-2.4	-1.1	-0.5	-0.2	-1.8	-1.8	-1.7	-1.3	-1.9	-2.1	-1.9	-1.7	-1.6	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	2.2	2.8	7.4	-1.4	-1.8	-1.8	-1.1	-2.0	-2.7	-2.1	-1.6	-1.4	-1.5	-2.1	-1.0	-1.3	-1.0	-1.5	-1.4	-1.7
Stomach or abdominal pain in last month	2.1	2.6	5.0	-1.9	-1.4	-1.0	-1.3	-1.1	-1.1	-2.2	-2.0	-1.9	-1.9	-1.4	-0.5	-1.6	-1.8	-1.8	-2.0	-1.4
High blood pressure (mother)	2.1	2.9	6.1	-1.9	-1.5	-2.5	-1.8	-1.4	-1.2	-1.7	-2.1	-1.7	-1.9	-1.9	-1.2	-1.6	-1.6	-1.6	-1.7	-1.2
Medication: Cholesterol lowering	2.1	3.2	5.2	-1.8	-2.2	-2.0	-0.2	-2.0	-1.4	-2.3	-1.6	-1.9	-1.8	-1.6	0.1	-1.7	-1.9	-1.9	-2.0	-2.3
Osteoarthritis (self-reported)	2.1	2.7	3.9	-1.7	-1.9	0.9	-1.3	-2.0	-1.6	-1.3	-1.7	-1.7	-1.7	-1.7	-1.0	-1.9	-1.7	-1.8	-1.7	-1.8
Medication: Lisinopril	2.1	2.7	6.0	-1.4	-2.2	0.6	-0.3	-2.5	-2.4	-1.8	-1.3	-1.4	-1.4	-1.9	-0.8	-1.5	-1.3	-1.6	-1.5	-2.0
Medication for cholesterol, blood pressure or diabetes	2.0	3.3	5.3	1.9	2.3	2.2	0.3	1.9	1.0	2.3	1.9	2.0	1.9	1.6	0.2	1.7	1.9	1.9	2.1	2.0
Shortness of breath walking on level ground	2.0	2.4	3.6	1.5	1.2	1.9	1.7	1.3	1.8	1.6	1.5	1.4	1.5	1.8	1.6	1.5	1.3	1.5	1.4	1.6
Neck or shoulder pain in last month	2.0	2.8	4.2	1.8	1.7	-0.1	2.0	2.0	1.6	1.0	1.8	1.8	1.8	1.9	0.4	1.9	1.9	1.8	1.7	1.8
Average weekly red wine intake	2.0	2.9	5.6	-1.5	-1.8	0.5	-1.0	-2.4	-1.8	-1.9	-1.5	-1.6	-1.6	-2.1	0.4	-1.7	-1.8	-1.8	-1.7	-2.4
Impedance of leg (right)	1.9	9.1	45.4	1.4	3.9	1.1	1.3	3.9	6.7	4.2	1.4	1.4	1.7	4.5	-1.1	1.7	1.1	2.1	1.6	4.3
Hair/balding pattern: Pattern 2	1.9	2.4	8.2	-1.3	-1.5	-0.9	-2.2	-1.8	-1.6	-0.6	-1.3	-1.2	-1.3	-1.8	-2.9	-1.4	-1.2	-1.4	-1.1	-1.6
Number of live births	1.9	2.7	4.0	1.7	2.0	0.2	1.7	1.8	1.9	1.6	1.7	1.7	1.7	1.9	0.6	1.7	1.5	1.7	1.6	1.8
Commuting to job workplace: Car/motor vehicle	1.9	2.1	3.6	1.8	1.5	0.4	0.7	1.5	0.2	1.6	1.6	1.8	1.7	1.1	1.0	1.6	1.9	1.7	1.8	1.5
Hearing aid user	1.9	2.2	3.3	-1.5	-1.2	-1.5	-1.3	-1.6	-1.8	-1.8	-1.5	-1.4	-1.5	-1.7	-1.1	-1.3	-1.3	-1.4	-1.4	-1.5
Impedance of whole body	1.9	9.4	55.8	1.0	3.9	0.5	1.3	3.9	7.5	4.1	1.2	1.1	1.5	4.7	-1.6	1.4	0.7	1.8	1.3	4.2
Ovarian Cancer	1.8	2.4	8.8	1.2	1.8	0.5	1.4	1.8	3.0	1.7	1.2	1.2	1.3	2.1	0.4	1.4	1.0	1.4	1.2	1.8
Age at last live birth	1.8	2.5	3.9	1.7	1.7	0.7	1.1	1.7	1.9	2.0	1.8	1.7	1.8	1.7	0.0	1.6	1.5	1.7	1.8	1.6
Pain type(s) experienced in last month: Hip pain	1.8	2.2	6.1	1.7	1.2	-1.0	2.5	0.6	1.6	1.8	1.9	1.6	1.7	1.3	0.5	1.4	1.4	1.5	1.6	1.0
Medication: Paracetamol	1.8	2.7	4.7	-1.6	-1.9	-1.1	-1.3	-2.1	-1.8	-1.6	-1.4	-1.6	-1.6	-1.9	0.1	-1.7	-1.7	-1.8	-1.6	-2.2
Systolic blood pressure, automated reading	1.7	4.9	10.4	-2.1	-2.7	-0.7	-1.3	-3.2	-1.9	-1.5	-2.0	-2.2	-2.2	-2.7	0.2	-2.5	-2.4	-2.3	-2.2	-2.9
Impedance of leg (left)	1.7	8.4	42.1	1.2	3.8	1.3	1.0	3.7	6.5	4.2	1.2	1.2	1.5	4.3	-1.3	1.4	0.9	1.9	1.4	4.1
Migraine (self-reported)	1.7	2.1	2.7	1.5	1.6	0.8	1.6	1.4	1.5	1.5	1.5	1.4	1.5	1.6	1.0	1.5	1.4	1.5	1.5	1.5
Age started oral contraceptive pill	1.7	2.1	4.2	-1.6	-2.0	0.2	-0.9	-1.7	-1.0	-1.0	-1.2	-1.5	-1.4	-1.4	-1.1	-1.8	-1.7	-1.6	-1.5	-1.9
Medication for hormone replacement therapy	1.6	1.8	3.0	1.5	1.5	0.4	1.5	1.5	0.3	0.5	1.4	1.5	1.5	1.2	1.1	1.7	1.7	1.5	1.5	1.4
Chronic bronchitis/emphysema (father)	1.6	1.8	3.5	-1.3	-1.4	-1.9	-1.4	-1.3	-1.1	-0.7	-1.0	-1.2	-1.1	-1.1	-1.8	-1.5	-1.4	-1.4	-1.2	-1.6
High blood pressure (siblings)	1.6	2.4	5.9	-1.5	-1.6	-2.4	-1.5	-1.3	-1.0	-1.7	-1.9	-1.6	-1.7	-1.7	0.4	-1.4	-1.4	-1.5	-1.6	-1.1
Illness, injury, bereavement, stress in last 2 years	1.6	1.9	3.0	-1.5	-1.6	-0.7	-1.2	-1.7	-0.8	-0.7	-1.6	-1.5	-1.6	-1.6	-0.2	-1.7	-1.6	-1.5	-1.5	-1.4
Medication: Blood pressure	1.5	2.9	6.3	-1.6	-2.5	-0.0	-1.6	-2.1	-1.9	-1.0	-1.4	-1.6	-1.6	-2.0	-0.8	-2.0	-1.7	-1.8	-1.6	-2.3
Fluid intelligence score	1.4	2.9	3.8	-1.8	-1.8	-1.3	-1.5	-1.8	-1.6	-1.6	-1.7	-1.7	-1.8	-1.9	-1.2	-1.9	-1.8	-1.8	-1.7	-1.9
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	2.8	1.5	1.4	1.3	1.7	0.8	1.3	1.5	1.5	1.5	1.5	1.2	0.8	1.5	1.4	1.4	1.5	1.1
Breastfed as a baby	1.4	1.7	5.9	-0.3	-1.8	-0.1	0.6	-2.4	-2.4	-0.9	-0.4	-0.5	-0.6	-2.1	1.1	-0.9	-0.4	-0.8	-0.5	-2.1
Osteoporosis (self-reported)	1.4	1.8	3.4	1.5	1.2	1.1	1.8	1.0	0.7	0.6	1.5	1.4	1.5	1.4	1.4	1.6	1.4	1.4	1.4	1.1
Medication: Aspirin	1.4	1.9	3.6	-1.1	-1.7	-1.6	-0.5	-1.6	-1.9	-1.8	-1.1	-1.1	-1.2	-1.5	-0.4	-1.1	-1.1	-1.3	-1.2	-1.8
Vascular/heart problems diagnosed by doctor	1.4	3.7	6.3	2.1	2.5	1.0	1.8	2.0	1.1	1.6	1.9	2.1	2.0	1.9	1.1	2.1	2.2	2.1	2.1	2.2
Verbal and Numeric Reasoning (VNR)	1.3	3.0	4.9	-1.9	-1.6	-0.6	-1.6	-1.7	-1.8	-2.2	-2.0	-1.8	-1.9	-2.0	-1.5	-1.6	-1.7	-1.8	-1.8	-1.7
Fasting Glucose	1.3	1.5	5.4	0.0	-0.5	2.1	-0.7	-1.9	-1.4	-1.0	0.0	0.0	-1.4	-1.5	-2.3	-1.4	0.0	0.0	0.0	-1.6
Tinnitus: Yes, but not now, but have in the past	1.3	1.3	16.4	1.0	0.2	-0.1	1.1	0.2	-0.6	-0.7	0.6	0.7	0.5	-0.2	4.0	0.9	0.8	0.6	0.6	-0.1
Impedance of arm (left)	1.3	6.1	42.9	0.5	2.9	-0.3	1.0	3.0	6.5	3.3	0.8	0.5	0.9	3.9	-1.4	0.8	0.0	1.1	0.6	3.2
Breast cancer (self-reported)	1.3	1.6	2.4	-1.2	-1.1	-1.5	-0.8	-1.4	-1.2	-1.5	-1.5	-1.3	-1.4	-1.5	0.7	-1.1	-1.1	-1.3	-1.3	-1.2
Risk taking	1.3	1.8	3.0	1.5	1.6	1.2	0.6	1.7	0.8	1.3	1.5	1.4	1.5	1.4	1.7	1.3	1.3	1.4	1.4	1.2
Medication: Omeprazole (e.g. Zanprol)	1.3	1.5	3.6	-1.2	-1.4	0.8	-1.2	-1.2	-1.9	-1.6	-1.1	-1.2	-1.2	-1.2	0.2	-1.2	-1.1	-1.3	-1.2	-1.5
Alzheimer’s Disease (in father)	1.2	1.4	2.6	1.2	1.2	1.5	0.8	1.3	-0.1	1.2	1.0	1.2	1.1	0.9	-0.2	1.0	1.6	1.3	1.3	1.5
Pulse wave peak to peak time	1.2	1.4	3.0	1.2	1.1	0.5	1.5	1.3	0.5	-0.5	0.9	1.2	1.1	0.8	1.7	1.7	1.4	1.2	1.1	1.1
Alcohol drinker status: Never	1.2	1.4	3.2	-1.3	-1.1	-1.8	-0.3	-1.1	-0.8	-1.3	-1.4	-1.2	-1.3	-1.1	-1.6	-1.1	-0.9	-1.1	-1.2	-0.7
Diastolic blood pressure, automated reading	1.2	3.7	9.4	-1.7	-2.4	-1.1	-1.2	-3.1	-1.8	-1.0	-1.6	-1.8	-1.8	-2.6	-0.1	-2.1	-2.0	-2.0	-1.8	-2.6
Impedance of arm (right)	1.1	5.0	37.1	0.3	2.4	-0.3	0.9	2.4	6.1	3.3	0.7	0.3	0.8	3.5	-1.2	0.5	-0.2	0.9	0.5	2.7
Eye problems/disorders: None of the above	1.1	1.3	2.3	1.0	1.3	0.8	1.2	1.2	1.5	1.2	1.2	1.1	1.2	1.5	0.4	1.1	0.9	1.1	1.1	1.2
Knee pain experienced in last month	1.1	1.8	6.6	1.2	1.0	1.8	1.1	0.4	1.4	2.6	1.5	1.3	1.4	1.4	-0.4	0.9	1.0	1.2	1.4	1.1
Mean Putamen Volume	1.0	1.2	3.0	-0.8	-1.1	-1.1	-1.7	-1.0	-1.3	-1.4	0.0	0.0	-1.4	-1.7	0.5	-1.4	0.0	0.0	0.0	-1.5
Age when periods started (menarche)	1.0	2.4	13.9	0.4	1.8	-0.1	1.3	2.1	3.7	1.3	0.8	0.5	0.9	2.9	-1.1	1.0	0.2	0.8	0.5	1.9
Mouth/teeth dental problems	1.0	1.5	3.9	1.3	0.9	0.9	0.6	0.8	1.0	2.0	1.4	1.5	1.4	0.9	-1.0	1.1	1.2	1.4	1.5	1.2
Pulse wave Arterial Stiffness index	1.0	1.2	3.1	-1.1	-1.0	-0.6	-1.4	-1.2	-0.2	0.6	-0.9	-1.1	-1.0	-0.7	-1.8	-1.6	-1.3	-1.2	-1.0	-0.9
Medication: Blood pressure	1.0	1.8	4.1	-1.5	-1.5	-1.7	0.2	-1.1	-0.3	-2.0	-1.5	-1.6	-1.5	-0.8	-0.1	-1.1	-1.4	-1.4	-1.7	-1.1
Medication: Ibuprofen	1.0	1.2	3.0	1.2	0.9	1.7	1.2	0.3	1.0	1.3	1.2	1.2	1.2	0.9	0.8	1.1	0.9	1.1	1.1	0.6
Suffer from ‘nerves’	1.0	1.6	3.7	-1.2	-1.2	-0.5	-1.9	-1.4	-1.0	-0.9	-1.2	-1.2	-1.2	-1.5	-1.2	-1.2	-1.3	-1.3	-1.2	-1.4
Medication: Bendroflumethiazide	1.0	1.5	3.4	-1.3	-1.8	0.7	-0.4	-1.5	-0.1	-0.5	-1.0	-1.3	-1.1	-0.8	-1.1	-1.5	-1.6	-1.4	-1.3	-1.5
Systolic Blood Pressure	0.9	4.3	9.4	-2.1	-2.3	-2.0	-0.5	-3.1	-1.7	-1.9	-2.2	-2.1	-2.2	-2.5	0.2	-2.1	-2.1	-2.1	-2.1	-2.4
Trunk fat percentage	0.9	3.5	14.2	1.2	1.6	1.7	2.1	1.8	3.8	2.5	1.9	1.3	1.7	2.9	-0.2	1.2	0.7	1.3	1.3	1.5
Forced vital capacity (FVC)	0.9	3.5	6.6	2.4	1.9	0.9	1.6	1.8	0.8	0.7	1.9	2.3	2.0	1.0	1.9	2.6	2.4	2.2	2.2	1.8
Financial difficulties in last 2 years	0.9	1.2	4.0	1.1	1.0	2.0	0.7	1.0	-0.4	0.1	1.2	1.2	1.2	0.8	-0.3	1.3	1.3	1.1	1.2	0.8
Illnesses of siblings	0.9	1.3	3.3	1.0	1.2	1.8	0.4	1.0	1.6	1.8	1.2	1.0	1.1	1.3	-0.0	0.8	0.7	0.9	1.0	0.8
Worrier / anxious feelings	0.9	1.7	5.8	-0.4	-1.9	0.1	-0.5	-2.4	-2.4	-0.8	-0.3	-0.5	-0.6	-2.0	-0.2	-0.9	-0.8	-1.0	-0.6	-2.3
Chronic bronchitis/emphysema (mother)	0.9	1.0	3.4	-1.0	-1.4	-0.6	-0.1	-1.9	-1.1	-0.6	-0.6	-0.8	-0.8	-1.1	-0.7	-1.0	-1.0	-1.0	-0.9	-1.5
Forced vital capacity (FVC), Best measure	0.9	3.4	6.4	2.3	2.0	0.7	1.6	2.0	0.9	0.5	1.7	2.2	1.9	1.2	1.9	2.5	2.4	2.2	2.1	1.9
Medication: Seretide 50 evohaler	0.9	1.0	3.1	1.1	0.9	0.0	1.8	0.4	0.5	0.9	1.2	1.2	1.2	0.8	-0.6	1.1	1.2	1.1	1.2	0.7
Illnesses of father: None of the above (group 1)	0.9	1.2	2.0	1.1	1.1	1.3	0.7	1.4	1.0	0.9	1.0	1.0	1.1	1.2	0.8	1.0	1.1	1.1	1.1	1.3
Ever smoked	0.9	1.6	4.1	-0.8	-1.5	1.0	0.0	-1.9	-2.0	-1.5	-0.5	-0.9	-0.8	-1.3	0.9	-1.0	-1.0	-1.1	-1.0	-2.0
Fractured/broken bones in last 5 years	0.9	1.1	2.4	-1.2	-0.6	-1.6	-1.2	-0.6	-1.1	-0.9	-1.3	-1.1	-1.2	-0.9	-1.4	-1.1	-0.7	-1.0	-1.0	-0.4
Hearing difficulty/problems: Yes	0.8	1.2	1.7	1.2	1.1	0.2	1.3	1.1	1.1	0.7	1.1	1.1	1.1	1.3	1.1	1.2	1.0	1.1	1.0	1.1
Standing height	0.8	8.1	18.2	2.5	2.8	2.9	3.3	2.6	4.3	3.0	2.9	2.5	2.8	3.8	-0.8	2.7	2.1	2.6	2.5	3.0
Gout (self-reported)	0.8	1.1	2.0	1.0	1.3	1.0	0.7	1.1	1.4	1.4	0.9	0.9	1.0	1.2	0.3	1.0	0.9	1.0	1.0	1.3
Comparative body size at age 10	0.8	2.2	11.6	-0.2	-1.8	-1.5	-1.1	-1.5	-3.4	-1.9	-0.5	-0.3	-0.6	-2.5	0.6	-0.7	-0.2	-0.7	-0.5	-2.0
Medication for pain relief, constipation, heartburn	0.8	1.3	3.0	1.1	1.4	0.5	0.5	1.5	1.1	1.2	0.9	1.2	1.1	1.1	-0.5	1.2	1.2	1.3	1.2	1.7
Handedness (chirality/laterality): Left-handed	0.8	0.9	2.2	1.0	1.1	-0.0	1.1	0.8	0.7	1.5	0.9	0.9	0.9	0.9	1.1	0.7	1.0	1.0	1.0	1.0
Friendships satisfaction	0.8	1.0	3.2	-1.1	-0.9	0.8	-0.6	-1.3	-0.6	-0.2	-0.9	-1.0	-0.9	-0.7	-1.8	-1.2	-1.0	-1.0	-0.9	-0.9
Ever taken oral contraceptive pill	0.8	0.9	2.0	-0.9	-1.3	1.2	-0.4	-1.4	-0.5	-0.3	-0.8	-1.0	-0.9	-0.7	-0.3	-0.9	-1.2	-1.1	-1.0	-1.1
Unable to work because of sickness or disability	0.8	1.0	2.0	1.1	1.0	0.8	1.3	0.7	0.1	0.7	1.4	1.1	1.3	1.4	0.5	1.1	1.1	0.9	1.1	0.6
Heart disease (siblings)	0.8	1.0	1.9	-1.1	-0.7	-1.2	-0.7	-1.0	-1.4	-1.4	-1.2	-1.0	-1.1	-1.0	-0.7	-0.8	-0.7	-0.9	-1.0	-0.7
Alzheimer’s Disease (in mother)	0.7	0.8	1.9	-0.9	-0.9	-0.1	-0.3	-0.6	-0.0	-1.4	-1.3	-1.1	-1.2	-0.8	0.7	-0.7	-1.0	-1.0	-1.2	-0.5
Age at First Birth	0.7	1.0	2.5	0.7	1.0	0.4	1.2	1.3	1.3	1.6	0.0	0.0	1.3	1.5	-0.7	1.2	0.0	0.0	0.0	1.3
Lupus	0.7	1.1	1.9	1.3	0.6	0.2	1.2	0.5	-0.3	0.6	1.4	1.4	1.3	0.4	1.1	1.2	1.3	1.2	1.3	0.5
Cardiovascular Disease	0.7	2.3	4.0	-1.5	-2.0	-0.1	-1.0	-1.7	-1.0	-1.8	-1.6	-1.6	-1.6	-1.7	-0.3	-1.5	-1.7	-1.6	-1.7	-1.8
Lung FEV1/FVC ratio	0.7	3.7	5.8	-2.4	-2.0	-1.7	-1.7	-1.6	-0.9	-1.7	-2.4	-2.4	-2.3	-1.4	-0.4	-2.2	-2.3	-2.2	-2.4	-1.6
Angina	0.7	0.9	4.2	-0.7	-1.3	-2.1	-0.8	-0.3	-0.8	-1.0	-0.6	-0.8	-0.7	-0.6	0.2	-0.8	-0.8	-0.9	-0.8	-1.2
Past tobacco smoking	0.7	1.3	4.4	0.6	1.6	-0.3	-0.5	1.8	2.1	1.3	0.3	0.7	0.6	1.1	-0.7	0.9	0.8	0.9	0.7	1.9
Exposure to tobacco smoke at home	0.7	0.8	2.0	-0.7	-0.9	-0.5	-0.4	-1.4	-1.3	-0.9	-0.7	-0.7	-0.8	-1.3	-0.4	-0.8	-0.8	-0.9	-0.8	-1.2
Body fat percentage	0.7	2.6	9.1	1.1	1.3	1.6	1.8	1.5	3.0	2.2	1.8	1.1	1.5	2.5	0.2	1.1	0.7	1.2	1.2	1.2
Alcohol intake frequency.	0.7	1.6	3.6	1.0	1.4	-0.8	1.2	1.8	1.6	0.8	0.8	1.1	1.0	1.5	0.7	1.4	1.3	1.3	1.1	1.9
Medication: Aspirin	0.7	0.9	3.3	-0.5	-1.2	-1.0	-0.2	-1.3	-1.8	-1.1	-0.5	-0.6	-0.6	-1.2	-0.3	-0.7	-0.5	-0.8	-0.6	-1.4
Hypertension (Self-reported)	0.7	1.9	3.2	-1.6	-1.8	0.1	-1.1	-1.5	-0.5	-1.4	-1.4	-1.5	-1.5	-1.2	-0.7	-1.4	-1.8	-1.5	-1.6	-1.5
Mood swings	0.7	1.3	2.6	-1.4	-1.2	-0.8	-0.7	-1.0	-0.6	-1.6	-1.4	-1.4	-1.4	-0.9	-0.3	-1.1	-1.3	-1.3	-1.4	-0.9
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.8	-0.9	-1.3	0.4	-0.3	-1.4	-0.9	-0.2	-0.6	-0.9	-0.8	-0.6	-0.0	-1.2	-1.0	-1.0	-0.9	-1.1
Average weekly beer plus cider intake	0.7	1.0	1.9	1.2	0.7	-0.5	1.4	0.6	0.4	1.0	1.4	1.2	1.3	0.9	0.3	0.9	1.1	1.1	1.2	0.6
Myopia	0.7	1.0	3.2	0.8	0.8	0.5	1.3	1.0	1.8	1.1	0.9	0.8	0.9	1.4	1.1	0.9	0.6	0.8	0.8	1.0
Schizophrenia (2018)	0.6	1.2	7.3	2.6	2.4	2.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.0	-0.4	0.0	0.0	0.0	0.0	-0.2
Schizophrenia vs Biploar Disorder	0.6	0.8	5.5	1.9	2.0	2.3	0.0	0.0	-0.4	0.0	0.0	0.0	0.0	-0.4	-0.7	0.0	0.0	0.0	0.0	-0.6
HbA1C	0.6	0.6	2.5	1.6	1.6	1.0	0.9	1.0	1.0	0.2	0.0	0.0	0.4	0.6	0.4	0.7	0.0	0.0	0.0	0.8
Ulcerative Colitis	0.6	0.9	3.6	-1.4	-1.7	-1.0	0.0	0.0	-1.4	0.0	0.0	0.0	0.0	-1.2	-1.5	0.0	0.0	0.0	0.0	-1.9
BMI	0.6	3.6	8.3	-1.3	-2.7	-0.4	-0.9	-2.4	-2.8	-2.2	-1.1	-1.4	-1.4	-2.4	1.5	-1.6	-1.5	-1.8	-1.5	-2.9
Hypothyroidism (self reported)	0.6	1.5	2.7	1.0	1.0	1.4	1.2	1.5	1.6	1.1	1.1	1.0	1.1	1.5	1.4	1.1	0.9	1.1	1.0	1.3
Relative age voice broke	0.6	0.9	4.9	-1.0	-0.7	-0.4	-0.7	-0.7	-0.6	-0.8	-1.0	-0.9	-0.9	-0.7	-2.2	-0.9	-0.8	-0.8	-0.9	-0.5
High blood pressure	0.6	1.8	3.2	-1.5	-1.8	-0.1	-1.2	-1.4	-0.4	-1.0	-1.4	-1.5	-1.4	-1.3	-0.8	-1.4	-1.7	-1.5	-1.5	-1.5
Trunk fat mass	0.6	2.6	7.1	1.3	1.1	1.9	2.2	1.3	2.7	1.9	1.9	1.3	1.7	2.4	0.2	1.3	0.8	1.3	1.3	1.0
Nervous feelings	0.6	1.2	2.5	-0.9	-1.0	-0.5	-0.6	-1.6	-0.9	-1.2	-1.1	-1.0	-1.1	-1.6	0.4	-1.1	-1.2	-1.1	-1.1	-1.5
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.4	0.7	1.1	0.9	0.9	1.0	1.0	0.7	0.7	0.7	0.8	1.2	-0.2	0.8	0.7	0.8	0.7	1.1
Medication: Paracetamol	0.6	1.0	1.9	-0.8	-1.2	-1.4	-0.5	-1.2	-1.0	-1.1	-0.8	-0.9	-0.9	-1.2	0.8	-0.9	-0.9	-1.0	-0.9	-1.3
Pulse rate, automated reading	0.6	1.8	3.8	-1.2	-1.8	-1.4	-0.2	-2.0	-1.6	-0.9	-1.0	-1.3	-1.2	-1.5	-0.2	-1.7	-1.2	-1.4	-1.3	-1.9
Loneliness, isolation	0.6	0.8	3.3	-0.8	-0.8	0.3	-0.0	-1.0	-1.8	-1.8	-0.8	-0.7	-0.7	-0.8	-0.5	-0.4	-0.3	-0.7	-0.7	-0.6
Ever had bowel cancer screening	0.6	0.6	5.8	0.5	-0.0	2.4	1.2	-0.4	0.3	1.0	0.8	0.6	0.6	0.3	-0.4	0.2	0.4	0.5	0.6	0.0
Back pain experienced in last month	0.6	0.9	2.2	-0.8	-1.2	-1.3	0.5	-1.5	-0.7	-0.6	-0.6	-0.9	-0.8	-0.7	0.5	-1.1	-0.9	-1.0	-0.9	-1.2
Mother’s age at death	0.6	0.8	1.5	0.9	0.6	-0.0	0.3	1.2	1.2	1.1	1.0	0.9	0.9	0.9	-1.1	0.7	0.6	0.9	0.9	0.9
High cholesterol (Self-reported)	0.6	1.1	3.1	-0.6	-1.3	1.0	-0.4	-1.2	-1.8	-1.2	-0.7	-0.7	-0.8	-1.5	0.5	-0.9	-0.7	-0.9	-0.8	-1.5
Irritable Bowel Disease (IBD)	0.5	1.3	2.1	-1.3	-1.4	-0.7	-0.9	-1.5	-0.8	-0.7	-1.1	-1.2	-1.1	-0.8	-1.3	-1.2	-1.3	-1.3	-1.2	-1.1
Sensitivity / hurt feelings	0.5	0.9	2.1	-0.8	-0.7	-0.4	-0.3	-1.1	-1.0	-1.1	-1.0	-1.0	-1.0	-1.0	1.4	-0.8	-0.8	-1.0	-1.0	-0.9
Vitamin and mineral supplements	0.5	0.7	1.7	1.0	0.7	0.8	1.2	0.1	1.0	1.3	0.9	0.9	0.9	0.6	0.4	0.7	0.8	0.8	0.9	0.5
Supplements: Zinc	0.5	0.5	1.7	-0.6	-0.3	1.3	-0.3	-0.3	-0.7	-1.2	-0.6	-0.6	-0.6	-0.6	1.3	-0.4	-0.6	-0.6	-0.7	-0.6
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	1.1	-0.7	-0.7	0.7	-0.8	-0.5	-0.8	-1.1	-0.7	-0.7	-0.7	-0.9	-0.4	-0.7	-0.6	-0.7	-0.7	-0.8
Sitting height	0.5	3.2	5.8	1.7	1.7	1.9	2.0	1.6	2.4	1.8	1.9	1.8	1.9	2.1	-0.6	1.8	1.5	1.8	1.7	1.8
Diabetes (self-reported)	0.5	0.8	2.0	-0.8	-1.2	1.1	0.0	-1.4	-0.8	-0.4	-0.5	-0.9	-0.7	-0.7	0.4	-1.1	-1.0	-1.0	-0.9	-1.3
Hair/balding pattern: Pattern 3	0.5	0.7	1.7	0.7	0.8	0.5	1.2	1.3	1.0	0.3	0.7	0.6	0.7	1.2	0.9	0.8	0.8	0.8	0.6	1.1
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	3.5	1.6	1.3	0.1	0.9	1.2	0.3	0.2	1.1	1.6	1.3	0.4	1.3	1.9	1.7	1.5	1.5	1.2
Exposure to tobacco smoke outside home	0.5	0.7	2.9	0.9	0.1	1.3	1.4	-0.1	-0.9	-0.6	0.7	0.8	0.7	-0.2	1.7	0.8	0.8	0.6	0.6	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.4	-0.8	-0.7	1.2	-0.7	-0.5	-0.2	-0.7	-0.8	-0.8	-0.8	-0.6	0.9	-0.8	-0.8	-0.8	-0.8	-0.7
Smoking status: Previous	0.5	0.8	2.6	-0.2	-1.2	0.6	0.9	-1.4	-1.6	-0.9	0.1	-0.3	-0.2	-0.8	0.8	-0.6	-0.4	-0.5	-0.4	-1.6
Commuting to job workplace: Walk	0.5	0.5	1.1	-0.7	-0.8	0.8	-0.7	-0.9	-0.7	-0.4	-0.4	-0.6	-0.6	-0.6	-0.5	-0.7	-0.8	-0.8	-0.6	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.1	-1.0	-0.6	-0.6	-0.4	-0.4	0.0	-1.0	-1.1	-1.0	-1.0	-0.2	0.2	-0.7	-0.9	-0.9	-1.1	-0.4
Financial situation satisfaction	0.5	0.6	7.2	-0.5	-0.4	0.3	-0.8	-0.5	-0.1	0.8	-0.2	-0.3	-0.2	-0.1	-2.7	-0.6	-0.4	-0.4	-0.2	-0.2
Illnesses of father: High blood pressure	0.5	0.6	6.0	0.5	0.4	-2.4	0.9	0.4	0.5	0.4	0.5	0.5	0.5	0.5	0.2	0.6	0.6	0.5	0.5	0.5
Number of operations (self-reported)	0.5	0.7	2.2	-0.3	-1.2	0.1	0.1	-1.1	-1.4	-1.0	-0.3	-0.4	-0.4	-1.0	1.5	-0.5	-0.4	-0.6	-0.5	-1.2
Breast Cancer	0.4	0.9	1.6	1.0	1.0	0.5	0.4	1.3	0.3	0.4	1.1	1.0	1.1	1.3	1.1	1.1	1.0	1.0	1.0	1.0
Waist Hip Ratio (WHR)	0.4	1.6	5.5	0.8	1.4	2.4	1.5	0.9	2.0	1.3	0.9	0.8	0.9	1.7	-0.3	0.9	0.7	1.0	0.8	1.4
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	3.3	0.7	0.2	1.8	0.6	0.0	-0.9	0.1	0.8	0.7	0.7	0.1	0.3	0.5	0.7	0.5	0.7	-0.1
Taking other prescription medications	0.4	0.6	1.3	-0.9	-1.0	-0.0	0.1	-0.7	0.0	-1.1	-0.8	-0.9	-0.8	-0.5	0.1	-0.7	-0.9	-0.9	-1.0	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	6.5	-0.3	-0.6	-0.8	-0.3	-1.3	-2.5	-1.2	-0.5	-0.2	-0.5	-1.7	-0.9	-0.4	0.2	-0.4	-0.3	-1.0
Multivitamins +/- minerals	0.4	0.5	1.7	-1.0	-0.3	-0.3	-1.1	0.1	-0.6	-1.3	-1.0	-0.8	-0.9	-0.5	-0.1	-0.5	-0.7	-0.7	-0.9	-0.2
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	2.3	0.8	0.2	0.9	1.2	-0.3	-0.5	-0.0	0.7	0.7	0.6	-0.1	1.5	0.5	0.6	0.5	0.6	-0.2
Medication: Atenolol	0.4	0.5	1.1	-0.9	-1.0	-0.9	-0.1	-0.6	-0.5	-0.8	-0.7	-0.8	-0.7	-0.4	-0.7	-0.7	-0.8	-0.8	-0.8	-0.8
Allergy	0.4	0.9	1.9	-1.0	-1.0	-0.6	-1.3	-1.0	-1.4	-0.7	-1.0	-0.9	-1.0	-1.0	-0.7	-0.9	-0.9	-1.0	-0.9	-0.8
Pain all over the body in last month	0.4	0.4	0.7	0.8	0.5	0.8	-0.3	0.7	0.1	0.6	0.7	0.8	0.7	0.5	-0.1	0.7	0.8	0.7	0.8	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	2.6	1.3	1.2	-0.1	0.9	1.1	0.5	-0.0	0.9	1.3	1.0	0.5	1.3	1.6	1.5	1.3	1.2	1.1
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	3.0	0.4	0.6	1.1	0.6	1.1	1.7	0.9	0.4	0.3	0.4	1.0	1.6	0.5	0.2	0.5	0.4	0.9
Leg fat percentage (right)	0.4	1.6	4.0	1.0	1.1	1.2	1.5	1.1	2.0	1.8	1.5	1.0	1.3	1.9	0.4	0.9	0.7	1.0	1.1	0.9
Whole body fat mass	0.4	1.6	3.7	1.1	0.7	1.7	1.9	0.8	1.8	1.5	1.7	1.1	1.4	1.8	0.4	0.9	0.7	1.0	1.0	0.5
Leg fat mass (right)	0.4	1.6	3.2	1.3	0.8	1.5	1.8	0.8	1.3	1.4	1.8	1.3	1.5	1.6	0.7	1.1	1.0	1.1	1.2	0.6
Chest pain or discomfort	0.4	0.5	4.3	-0.6	-0.7	-2.1	-0.2	-0.3	-0.3	-0.6	-0.5	-0.6	-0.5	-0.2	-0.3	-0.6	-0.6	-0.6	-0.7	-0.6
Medication for cholesterol	0.4	0.5	1.4	0.5	1.1	-0.6	0.9	0.5	1.2	0.6	0.5	0.6	0.6	0.9	-0.6	0.8	0.6	0.7	0.5	1.0
Average weekly champagne plus white wine intake	0.4	0.6	4.8	0.3	-0.4	2.2	0.9	-0.8	-1.2	-0.2	0.6	0.4	0.5	-0.2	0.4	0.2	0.3	0.2	0.4	-0.6
Commuting to job workplace: Public transport	0.4	0.5	1.3	-0.4	-0.6	-0.7	-0.5	-1.2	-1.0	-0.4	-0.5	-0.4	-0.5	-1.1	-1.1	-0.6	-0.4	-0.5	-0.4	-0.8
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.2	0.8	0.8	0.5	0.1	1.1	0.1	0.1	0.6	0.8	0.7	0.5	0.3	0.9	0.9	0.8	0.8	0.8
Leg fat mass (left)	0.4	1.5	2.9	1.2	0.7	1.6	1.7	0.8	1.0	1.3	1.7	1.2	1.4	1.5	0.7	1.0	0.9	1.1	1.2	0.5
Intelligence (Savage-Jansen 2018)	0.3	0.9	2.9	-0.7	-1.0	0.9	-0.8	-1.2	-1.7	-1.2	-0.4	-0.6	-0.6	-1.1	-0.7	-0.6	-0.7	-0.8	-0.6	-1.4
Neuroticism (Nagel 2018)	0.3	0.6	2.1	-0.5	-1.1	0.8	-0.2	-1.5	-1.1	-0.9	-0.4	-0.5	-0.5	-0.9	0.3	-0.5	-0.6	-0.7	-0.6	-1.2
Worry (Nagel 2018)	0.3	0.7	2.8	-0.5	-1.2	0.5	-0.3	-1.7	-1.0	-0.5	-0.2	-0.6	-0.5	-0.9	0.3	-0.7	-0.9	-0.8	-0.6	-1.5
Body Mass Index (BMI) (2010)	0.3	0.4	1.6	1.1	0.8	1.1	0.7	0.0	-0.6	0.0	0.0	0.0	0.0	-0.2	1.3	0.7	0.0	0.0	0.0	0.1
HDL Cholesterol	0.3	0.4	2.0	-1.0	-1.3	0.2	0.0	0.0	-1.2	0.0	0.0	0.0	0.0	-1.1	-0.3	0.0	0.0	0.0	0.0	-1.4
Blood White Count	0.3	2.1	7.9	0.9	1.8	-0.2	1.6	1.7	2.8	1.3	0.5	0.7	0.7	1.9	1.7	1.2	0.9	1.1	0.8	2.2
Height	0.3	6.7	17.1	2.1	2.4	2.6	3.5	2.3	4.1	2.1	2.6	2.3	2.5	3.5	-0.6	2.7	1.8	2.4	2.1	2.5
Smoking Status	0.3	0.8	2.6	0.9	0.6	1.6	1.4	0.1	-0.9	0.0	1.1	0.9	1.0	0.7	0.4	0.9	1.0	0.7	0.9	0.3
Chronotype (morning person)	0.3	0.7	2.5	-0.3	-1.1	0.5	-1.3	-1.1	-1.4	-0.4	-0.4	-0.3	-0.5	-1.6	-0.1	-0.6	-0.5	-0.6	-0.3	-1.2
Average weekly spirits intake	0.3	0.3	1.1	0.6	0.5	0.9	-0.3	0.2	-1.1	0.2	0.5	0.6	0.5	-0.4	0.5	0.4	0.8	0.5	0.7	0.2
Medication: Co-codamol	0.3	0.3	2.0	-0.5	-0.3	0.3	0.2	0.2	1.4	0.0	-0.4	-0.6	-0.4	0.6	0.1	-0.5	-0.7	-0.5	-0.6	0.0
Average weekly fortified wine intake	0.3	0.4	1.1	0.8	0.4	1.0	0.2	0.3	0.1	1.0	0.6	0.7	0.7	0.3	0.4	0.5	0.8	0.7	0.8	0.7
Supplements: Glucosamine	0.3	0.4	2.9	0.6	-0.0	1.7	0.3	-0.3	-0.0	1.1	0.8	0.5	0.6	0.3	-0.2	0.3	0.4	0.4	0.6	-0.0
Number of incorrect matches in round	0.3	0.4	1.0	0.8	0.6	0.7	0.5	0.7	0.5	1.0	0.7	0.7	0.7	0.5	0.5	0.5	0.7	0.7	0.8	0.6
Alcohol usually taken with meals	0.3	0.6	3.0	-0.4	-0.8	1.7	-0.1	-1.0	-0.5	-0.2	-0.3	-0.5	-0.5	-0.8	0.6	-0.8	-0.7	-0.6	-0.5	-1.0
Had menopause	0.3	0.4	0.9	-0.5	-0.8	0.7	-0.5	-0.9	-0.6	0.3	-0.4	-0.5	-0.5	-0.8	0.4	-0.8	-0.6	-0.6	-0.4	-0.7
Qualifications: None of the above	0.3	0.7	5.1	-0.7	0.3	0.3	-0.2	0.7	2.3	0.8	-0.5	-0.8	-0.5	1.3	0.4	-0.5	-0.9	-0.4	-0.7	0.7
Neuroticism score	0.3	0.5	1.6	-0.5	-0.8	0.5	-0.2	-1.3	-0.8	-0.7	-0.5	-0.6	-0.6	-0.9	0.9	-0.5	-0.6	-0.7	-0.6	-1.0
Noisy workplace	0.3	0.4	1.1	0.7	0.2	1.1	0.6	0.3	-0.8	-0.5	0.5	0.7	0.5	0.1	0.8	0.9	0.9	0.6	0.6	0.4
Mouth/teeth dental problems: Dentures	0.3	0.4	2.7	-0.5	-0.6	-1.6	-0.5	-0.2	-0.6	-0.7	-0.8	-0.6	-0.7	-0.6	0.2	-0.5	-0.4	-0.6	-0.6	-0.2
Peak expiratory flow (PEF)	0.3	0.6	1.2	1.1	0.7	-0.3	0.6	0.7	0.4	0.5	0.9	1.0	0.9	0.3	0.8	1.1	1.0	1.0	1.0	0.6
Loud music exposure frequency	0.3	0.4	3.6	0.1	0.5	-0.6	0.2	0.6	-0.0	-1.0	-0.2	0.0	-0.1	0.1	1.9	0.5	0.2	0.1	-0.1	0.3
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	0.9	0.9	0.8	0.6	0.4	0.9	-0.0	0.1	0.5	0.8	0.6	0.2	0.8	0.8	0.9	0.8	0.8	0.8
Headache pain in last month	0.3	0.6	1.3	0.7	1.0	0.5	1.2	0.7	0.9	0.8	0.7	0.6	0.7	0.9	0.6	0.5	0.7	0.7	0.6	0.8
Medication: Ventolin 100micrograms inhaler	0.3	0.3	0.9	0.5	0.9	0.1	0.5	1.0	-0.1	0.1	0.4	0.5	0.5	0.7	0.1	0.6	0.7	0.6	0.5	0.8
Arm fat-free mass (right)	0.3	1.3	4.8	1.2	-0.3	2.2	1.6	-0.2	-1.6	-0.5	1.4	1.3	1.2	-0.1	0.6	1.2	1.3	0.9	1.1	-0.4
Angina (self-reported)	0.3	0.4	2.3	-0.4	-0.9	-1.5	-0.6	0.0	-0.6	-0.7	-0.2	-0.4	-0.3	-0.3	0.5	-0.5	-0.5	-0.5	-0.4	-0.8
Mean time to correctly identify matches	0.3	0.5	1.7	-0.7	-0.7	0.6	0.0	-1.3	0.7	0.8	-0.4	-0.7	-0.5	-0.3	-1.1	-0.9	-1.0	-0.7	-0.6	-0.7
Family relationship satisfaction	0.3	0.4	2.4	-0.8	-0.5	-0.1	-0.8	-0.5	-0.2	0.1	-0.5	-0.6	-0.5	-0.2	-1.6	-0.7	-0.7	-0.6	-0.5	-0.4
Leg pain on walking	0.3	0.3	2.1	0.5	0.3	1.5	1.3	-0.1	0.0	0.1	0.5	0.4	0.5	0.4	0.3	0.5	0.5	0.4	0.4	0.3
Supplements: Vitamin C	0.3	0.4	1.2	0.5	0.6	-0.3	1.1	0.4	0.6	0.4	0.7	0.6	0.7	0.7	-0.4	0.7	0.5	0.6	0.6	0.5
Diabetes diagnosed by doctor	0.3	0.5	3.0	0.7	0.3	1.7	1.1	0.2	0.1	0.8	0.9	0.6	0.7	0.7	0.7	0.4	0.5	0.5	0.6	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.5	0.3	0.6	-0.6	0.1	0.7	1.2	0.3	-0.0	0.1	0.1	0.5	1.2	0.3	0.2	0.3	0.1	0.7
Medication: Gliclazide	0.3	0.4	0.8	-0.9	-0.6	-0.3	-0.1	-0.4	0.2	-0.5	-0.7	-0.8	-0.7	-0.1	-0.7	-0.7	-0.7	-0.7	-0.8	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	1.8	1.1	0.4	0.1	0.8	0.4	-0.8	0.4	0.9	1.1	1.0	0.1	0.6	0.9	1.3	1.0	1.1	0.5
Irritability	0.3	0.6	1.3	-0.4	-0.8	0.9	-0.5	-1.1	-0.9	-0.8	-0.4	-0.5	-0.5	-1.0	0.7	-0.5	-0.6	-0.7	-0.6	-1.1
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.5	-0.6	-0.2	-1.2	0.2	0.1	1.1	0.1	-0.7	-0.6	-0.6	0.4	-0.5	-0.4	-0.6	-0.4	-0.6	0.3
Cholesterol lowering medication	0.3	0.4	1.9	-0.2	-0.4	1.4	-0.9	-0.2	-1.4	-0.8	-0.4	-0.2	-0.3	-1.0	0.1	-0.4	-0.1	-0.3	-0.2	-0.6
Alcohol drinker status: Previous	0.3	0.3	0.9	0.3	0.6	0.2	-0.1	0.9	0.3	0.8	0.4	0.4	0.5	0.9	0.2	0.4	0.5	0.5	0.5	0.9
Pack years of smoking	0.3	0.4	0.8	-0.8	-0.5	-0.6	-0.5	-0.3	0.7	0.4	-0.6	-0.8	-0.6	0.3	-0.3	-0.9	-0.9	-0.7	-0.7	-0.3
Bipolar Disorder (2018)	0.2	0.4	3.1	-1.8	-1.6	-0.3	0.0	0.0	-0.3	0.0	0.0	0.0	0.0	-0.4	-0.1	0.0	0.0	0.0	0.0	-0.5
Depressed Affect (Nagel 2018)	0.2	0.3	0.9	-0.4	-0.8	0.2	-0.1	-0.9	-0.8	-1.0	-0.5	-0.4	-0.5	-0.7	-0.1	-0.2	-0.3	-0.5	-0.5	-0.6
Depression (Nagel 2018)	0.2	0.3	1.2	-0.5	-0.4	1.1	-0.7	-0.6	-0.3	0.1	-0.5	-0.5	-0.5	-0.3	-0.2	-0.4	-0.5	-0.5	-0.4	-0.2
Reaction Time	0.2	0.4	1.5	-0.2	-0.1	1.2	0.5	-0.9	0.8	1.1	0.1	-0.2	-0.0	0.3	-1.2	-0.3	-0.5	-0.2	-0.1	-0.2
Prostate Cancer	0.2	0.3	1.0	-0.3	-0.6	-1.0	0.5	-0.9	-0.4	-0.5	-0.2	-0.3	-0.3	-0.4	-0.4	-0.3	-0.4	-0.4	-0.4	-0.6
Neuroticism (2016)	0.2	0.2	1.6	0.3	0.4	0.0	0.3	0.5	1.3	0.3	0.2	0.1	0.2	0.8	0.8	0.5	0.1	0.2	0.1	0.5
Primary Biliary Cirrhosis	0.2	0.2	1.3	0.8	1.0	1.1	0.4	0.0	0.4	0.0	0.0	0.0	0.0	0.5	-0.3	0.0	0.0	0.0	0.0	0.7
Schizophrenia (2014)	0.2	0.5	4.8	1.3	1.1	2.2	0.0	0.0	-0.2	0.0	0.0	0.0	0.0	-0.3	-0.8	0.0	0.0	0.0	0.0	-0.6
Blood Eosinophil Count	0.2	1.4	2.7	1.5	0.7	-0.0	1.4	0.4	0.4	1.6	1.6	1.5	1.5	0.9	-0.4	1.1	1.4	1.3	1.5	0.8
Blood Red Count	0.2	1.5	2.3	-1.2	-1.2	-0.2	-0.9	-1.2	-0.8	-1.5	-1.3	-1.3	-1.3	-1.3	1.0	-1.2	-1.4	-1.3	-1.4	-1.5
Lung FVC	0.2	1.2	3.0	1.6	0.8	-0.1	0.1	0.7	-1.3	0.2	1.0	1.5	1.1	-0.4	1.5	1.3	1.7	1.3	1.4	0.6
Neuroticism	0.2	0.5	1.7	-0.3	-1.0	-0.6	-0.0	-1.3	-1.0	-0.7	-0.4	-0.5	-0.5	-0.9	1.0	-0.5	-0.5	-0.7	-0.5	-1.0
Relative age of first facial hair	0.2	0.5	3.0	-0.1	0.4	1.4	0.1	0.4	1.7	1.2	0.0	-0.1	0.0	0.9	-0.4	-0.1	-0.3	0.0	-0.0	0.6
Medication: Metformin	0.2	0.3	3.0	0.2	0.1	1.7	1.1	0.1	0.2	0.2	0.3	0.1	0.2	0.5	1.0	0.0	0.1	0.1	0.1	0.1
Severe depression (siblings)	0.2	0.2	0.4	0.4	0.5	-0.5	0.1	0.1	-0.6	0.3	0.3	0.4	0.4	-0.0	0.6	0.3	0.6	0.4	0.5	0.2
Pack years adult smoking proportion	0.2	0.3	1.2	-0.6	-0.1	-0.6	-0.4	0.0	1.1	0.8	-0.4	-0.6	-0.4	0.6	-0.5	-0.6	-0.7	-0.5	-0.5	0.1
Leg fat-free mass (left)	0.2	1.0	2.6	1.1	-0.4	1.3	1.6	-0.3	-1.2	-0.5	1.4	1.1	1.2	0.0	0.6	1.0	1.0	0.7	1.0	-0.6
Hand grip strength (right)	0.2	0.4	1.3	-0.5	-0.3	0.8	-1.0	-0.8	-1.1	-0.7	-0.7	-0.4	-0.6	-1.1	0.1	-0.3	-0.3	-0.5	-0.4	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.7	-0.5	-0.0	1.3	-0.6	-0.1	-0.1	-0.3	-0.4	-0.4	-0.4	0.2	-0.6	-0.2	-0.4	-0.4	-0.4	0.1
Qualifications: CSEs or equivalent	0.2	0.2	0.9	-0.1	0.7	-0.9	-0.1	0.7	0.8	0.3	-0.1	0.0	0.0	0.6	-0.7	0.2	0.1	0.2	0.1	0.8
Serious illness, injury or assault to yourself	0.2	0.3	1.5	0.5	0.1	-1.2	0.4	0.1	-0.5	0.5	0.7	0.5	0.6	0.4	-0.2	0.4	0.6	0.4	0.6	0.1
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.4	0.7	0.6	0.7	0.7	0.8	1.2	0.6	0.8	0.6	0.7	0.8	0.7	0.5	0.5	0.6	0.6	0.4
Body mass index (BMI)	0.2	0.9	4.2	-0.2	-1.4	0.4	0.2	-1.3	-2.0	-1.0	0.1	-0.2	-0.2	-1.1	0.9	-0.5	-0.3	-0.6	-0.3	-1.7
Leg predicted mass (left)	0.2	1.0	2.7	1.1	-0.4	1.3	1.6	-0.3	-1.2	-0.4	1.5	1.2	1.2	0.0	0.6	1.1	1.0	0.8	1.0	-0.6
Waist circumference	0.2	0.7	3.0	0.8	-0.1	1.6	1.7	-0.2	0.1	0.4	1.2	0.7	0.9	0.6	0.8	0.5	0.5	0.5	0.6	-0.4
Hearing difficulty/problems with background noise	0.2	0.3	1.2	0.3	0.7	-0.0	0.2	0.8	0.5	-0.5	-0.0	0.3	0.2	0.2	1.1	0.7	0.4	0.4	0.2	0.6
Had other major operations	0.2	0.3	2.9	0.3	-0.5	-0.5	0.7	-0.5	-0.1	0.1	0.2	0.1	0.1	-0.3	1.7	0.0	0.0	0.0	0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.8	0.3	-0.1	-1.0	-0.2	-0.8	-1.7	-0.1	0.1	0.3	0.1	-1.1	-1.5	0.0	0.6	0.1	0.3	-0.4
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.1	0.2	0.2	0.5	1.0	0.4	1.1	-0.1	0.4	0.2	0.3	0.7	0.1	0.3	-0.0	0.2	0.1	0.1
Weight	0.2	0.9	3.0	1.0	0.1	1.7	1.7	0.1	0.1	0.5	1.5	1.1	1.2	0.8	0.5	0.9	0.8	0.8	1.0	-0.1
Trunk fat-free mass	0.2	1.2	5.2	0.9	-0.9	1.7	1.4	-0.8	-2.3	-0.9	1.1	0.9	0.9	-0.7	1.2	0.8	0.9	0.5	0.8	-1.0
Alcohol intake versus 10 years previously	0.2	0.4	2.5	-0.1	0.5	-0.9	0.6	0.7	1.6	0.2	-0.0	-0.1	0.0	1.1	0.1	0.3	-0.1	0.1	-0.1	0.7
Father’s age at death	0.2	0.3	2.1	-0.0	-0.3	0.8	0.8	-0.8	0.1	0.5	0.2	-0.0	0.1	-0.0	-1.4	-0.3	-0.1	-0.1	0.0	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.0	0.3	0.4	0.5	0.9	0.6	0.0	-0.3	0.6	0.4	0.5	1.0	-0.1	0.6	0.5	0.4	0.3	0.4
Pulse rate	0.2	0.3	0.8	-0.4	-0.9	-0.1	0.2	-0.6	-0.2	-0.6	-0.3	-0.5	-0.4	-0.4	0.6	-0.6	-0.6	-0.5	-0.5	-0.7
Happiness	0.2	0.2	0.8	-0.4	-0.5	0.1	-0.4	-0.6	0.1	0.7	-0.4	-0.4	-0.4	-0.1	-0.9	-0.7	-0.5	-0.4	-0.3	-0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.5	-0.4	-0.7	-0.3	-0.4	-0.7	-0.9	-1.2	-0.5	-0.5	-0.5	-1.2	0.3	-0.6	-0.5	-0.6	-0.6	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.7	0.5	-0.1	-0.7	0.8	-0.2	0.1	-0.1	0.3	0.4	0.3	-0.2	0.8	0.5	0.3	0.4	0.3	-0.1
Depression (self-reported)	0.2	0.3	1.5	0.5	0.2	1.2	-0.4	0.2	-0.9	-0.0	0.5	0.6	0.5	-0.1	-0.4	0.6	0.6	0.4	0.6	0.3
Prospective memory result	0.2	0.2	1.3	0.1	0.5	0.2	-0.9	1.1	-0.0	0.3	-0.2	0.1	0.0	0.3	0.4	0.1	0.5	0.3	0.2	0.9
Arm fat mass (right)	0.2	0.7	2.9	0.8	-0.1	1.3	1.7	-0.0	0.4	0.7	1.3	0.8	1.0	0.8	0.7	0.5	0.5	0.5	0.7	-0.3
Trunk predicted mass	0.2	1.2	5.6	0.8	-1.0	1.6	1.3	-0.9	-2.4	-1.1	1.0	0.8	0.7	-0.8	1.1	0.6	0.8	0.4	0.6	-1.1
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.6	-0.7	0.1	0.8	0.5	-0.2	0.7	-0.6	-0.5	-0.6	-0.5	0.4	-0.1	-0.3	-0.6	-0.5	-0.7	-0.1
Birth weight	0.2	0.4	1.6	0.1	0.6	0.6	0.5	1.0	1.3	0.4	0.3	0.2	0.3	1.1	0.1	0.3	0.1	0.3	0.2	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.1	0.3	0.5	1.1	0.3	-0.0	-0.2	0.3	0.3	0.4	0.3	0.1	-0.9	0.3	0.4	0.3	0.4	0.3
Health satisfaction	0.2	0.3	1.2	0.4	0.3	1.1	0.9	-0.0	-0.2	0.4	0.7	0.5	0.6	0.8	-0.6	0.4	0.4	0.4	0.5	0.2
Medication: Allopurinol	0.2	0.3	1.5	-0.5	-0.4	-0.8	-0.4	-0.1	0.5	-0.3	-0.6	-0.6	-0.6	-0.3	1.2	-0.3	-0.6	-0.5	-0.6	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.3	-0.5	0.0	-0.6	0.7	0.0	0.8	-0.3	-0.3	-0.4	-0.3	0.5	-1.1	-0.3	-0.5	-0.3	-0.5	0.1
Arm predicted mass (right)	0.2	1.1	3.8	1.0	-0.5	1.9	1.3	-0.4	-1.8	-0.7	1.2	1.1	1.0	-0.3	0.7	0.9	1.0	0.7	0.9	-0.7
Comparative height size at age 10	0.2	1.3	2.3	0.9	0.7	0.8	1.5	0.8	1.4	1.5	1.2	1.0	1.2	1.5	-1.0	0.9	1.0	1.0	1.1	1.1
Number of full sisters	0.2	0.2	0.8	-0.6	-0.2	-0.9	-0.0	0.1	0.4	-0.6	-0.4	-0.6	-0.4	0.3	-0.0	-0.3	-0.6	-0.5	-0.6	-0.1
Overall health rating	0.2	0.4	1.5	0.0	-0.2	1.2	1.2	-0.2	0.0	0.0	0.7	0.2	0.5	0.8	-1.2	0.1	0.1	0.0	0.1	-0.3
Illnesses of father: Heart disease	0.2	0.3	0.9	-0.6	-0.4	-0.6	-0.2	0.1	0.9	-0.4	-0.7	-0.6	-0.6	-0.1	0.5	-0.3	-0.7	-0.5	-0.7	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.5	0.6	0.6	0.2	0.2	0.6	1.2	1.0	0.6	0.6	0.6	0.7	-0.8	0.6	0.4	0.6	0.6	0.6
Whole body fat-free mass	0.2	1.2	4.0	1.0	-0.7	1.6	1.5	-0.7	-2.0	-0.8	1.3	1.0	1.0	-0.5	0.9	0.9	1.0	0.6	0.9	-0.9
Leg fat-free mass (right)	0.2	0.9	2.8	0.9	-0.6	1.3	1.4	-0.6	-1.7	-0.8	1.2	1.0	0.9	-0.4	0.5	0.8	0.9	0.5	0.8	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	1.6	-0.2	-0.5	-0.4	-0.6	-0.5	-1.2	-0.9	-0.2	-0.3	-0.3	-0.8	1.0	-0.4	-0.3	-0.4	-0.3	-1.0
Mineral and other dietary supplements	0.2	0.3	1.0	-0.5	-0.5	-1.0	-0.1	-0.6	-0.3	-0.1	-0.4	-0.5	-0.5	-0.2	0.1	-0.6	-0.5	-0.5	-0.5	-0.6
Smoking status: Current	0.2	0.3	2.2	-0.5	0.1	0.4	-1.0	-0.3	-0.8	-0.2	-0.5	-0.4	-0.4	-0.0	-1.5	-0.2	-0.2	-0.4	-0.3	0.1
Whole body water mass	0.2	1.2	4.5	1.0	-0.8	1.7	1.5	-0.8	-2.1	-0.8	1.3	1.0	1.0	-0.5	0.8	0.8	1.0	0.6	0.8	-1.0
Leg predicted mass (right)	0.2	0.9	2.9	0.9	-0.7	1.2	1.4	-0.6	-1.7	-0.8	1.2	0.9	0.9	-0.4	0.5	0.8	0.8	0.5	0.8	-0.9
Number of self-reported non-cancer illnesses	0.2	0.4	1.6	-0.6	-0.5	1.3	-0.0	-0.9	0.1	0.2	-0.3	-0.5	-0.4	-0.1	-1.2	-0.6	-0.7	-0.6	-0.5	-0.5
Eye problems/disorders: Glaucoma	0.2	0.2	0.7	-0.3	-0.4	0.8	0.1	-0.5	-0.8	-0.5	-0.4	-0.3	-0.4	-0.5	0.4	-0.3	-0.1	-0.3	-0.3	-0.3
Basal metabolic rate	0.2	1.3	3.4	1.3	-0.3	1.8	1.8	-0.3	-1.3	-0.3	1.6	1.3	1.3	0.1	0.9	1.1	1.2	0.9	1.1	-0.5
Leg fat percentage (left)	0.2	0.9	2.0	0.7	0.7	1.3	1.1	0.8	1.4	1.3	1.1	0.7	0.9	1.4	0.5	0.5	0.4	0.7	0.7	0.5
Arm fat-free mass (left)	0.2	1.1	3.7	0.9	-0.7	1.8	1.4	-0.7	-1.9	-0.7	1.2	1.0	0.9	-0.5	0.7	0.8	0.9	0.5	0.8	-0.8
Basal cell carcinoma (self-reported)	0.2	0.2	0.7	-0.5	0.3	-0.6	-0.9	0.8	0.0	-0.5	-0.5	-0.4	-0.4	0.1	-0.3	-0.3	-0.2	-0.2	-0.3	0.3
Arm predicted mass (left)	0.2	1.1	4.4	0.9	-0.7	2.1	1.4	-0.6	-1.9	-0.6	1.2	1.0	0.9	-0.4	0.5	0.8	0.9	0.6	0.8	-0.8
Bipolar Disorder or Schizophrenia	0.1	0.2	2.1	0.6	0.6	1.4	-0.5	0.0	-0.1	0.0	0.0	0.0	0.0	-0.3	-0.5	0.0	0.0	0.0	0.0	-0.4
Alzheimer’s Disease (including proxy)	0.1	0.1	0.6	-0.1	-0.1	0.1	0.3	0.1	-0.3	-0.8	-0.5	-0.2	-0.3	-0.4	0.8	0.0	0.1	-0.1	-0.2	0.1
Crohns Disease (2017)	0.1	0.3	0.8	0.4	0.3	-0.2	0.8	0.5	0.6	0.5	0.5	0.4	0.5	0.9	0.2	0.5	0.4	0.4	0.4	0.6
Major Depression (MDD)	0.1	0.1	0.7	0.2	-0.6	0.2	0.4	-0.5	0.1	0.8	0.4	0.1	0.3	0.1	-0.0	-0.2	-0.1	0.0	0.2	-0.4
Bipolar Disorder (2011)	0.1	0.1	1.0	-1.0	-0.9	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.3	0.1	0.0	0.0	0.0	0.0	0.4
Coronary Artery Disease (CAD)	0.1	0.1	1.2	-0.9	-0.6	-1.1	0.0	0.0	-0.0	0.0	0.0	0.0	0.0	-0.1	-0.2	0.0	0.0	0.0	0.0	-0.2
LDL Cholesterol	0.1	0.1	0.8	-0.3	-0.6	0.4	0.0	0.0	-0.5	0.0	0.0	0.0	0.0	-0.3	-0.9	0.0	0.0	0.0	0.0	-0.6
Rheumatoid Arthritis	0.1	0.1	0.5	-0.7	-0.5	-0.0	-0.2	0.0	-0.1	0.0	0.0	0.0	0.0	-0.1	-0.7	0.0	0.0	0.0	0.0	-0.0
Triglycerides	0.1	0.2	0.9	-0.2	0.1	-0.9	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.7	-0.1	0.0	0.0	0.0	0.0	0.9
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.3	-0.3	-0.1	-0.5	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.4	-0.1	0.0	0.0	0.0	0.0	0.6
Blood Platelet Count	0.1	0.8	2.1	1.0	0.8	0.0	1.5	0.5	0.9	1.4	0.8	0.9	0.8	0.8	0.6	0.7	1.0	1.0	0.9	1.1
Heel T-Score	0.1	0.7	2.9	0.9	0.5	-0.3	-0.5	0.7	-1.7	-0.2	0.5	0.9	0.6	-0.7	1.3	0.7	1.2	0.8	0.9	0.2
Allergy or Eczema	0.1	0.2	0.7	-0.6	-0.4	-0.2	-0.3	0.0	0.8	-0.3	-0.5	-0.6	-0.5	-0.1	0.0	-0.6	-0.7	-0.5	-0.6	-0.4
Respiratory disease	0.1	0.2	1.1	-0.5	-0.2	0.2	0.3	-0.3	-0.5	-1.1	-0.7	-0.5	-0.5	-0.4	-0.5	-0.2	-0.2	-0.4	-0.5	-0.1
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.5	-0.1	-0.2	0.6	0.7	-0.3	0.3	0.5	0.1	-0.2	0.0	0.4	0.7	-0.2	-0.2	-0.1	-0.1	-0.1
Tanning	0.1	0.7	4.7	0.8	0.7	1.2	0.7	0.7	-0.2	-0.1	0.5	0.7	0.6	0.2	2.2	0.8	0.8	0.7	0.7	0.6
Hand grip strength (left)	0.1	0.2	2.5	0.4	0.4	1.6	-0.3	-0.1	-0.4	0.2	0.2	0.4	0.3	-0.3	0.3	0.4	0.4	0.3	0.4	0.1
Frequency of depressed mood in last 2 weeks	0.1	0.1	1.3	-0.4	0.2	1.1	-0.1	-0.0	0.1	-0.0	-0.4	-0.4	-0.3	0.5	-0.0	-0.1	-0.2	-0.3	-0.3	0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.9	0.0	0.2	-0.5	0.9	-0.1	0.0	-0.6	-0.1	0.1	0.0	0.0	-0.5	0.3	0.3	0.1	0.0	0.1
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.4	-0.4	-0.3	-0.2	-0.5	-0.0	-0.2	-0.6	-0.6	-0.4	-0.5	-0.6	0.5	-0.3	-0.2	-0.3	-0.4	-0.2
Ever had hysterectomy (womb removed)	0.1	0.1	0.3	-0.1	0.3	0.2	-0.1	0.6	0.3	0.2	0.1	0.1	0.1	0.3	-0.2	-0.0	0.1	0.1	0.1	0.5
Diabetes (father)	0.1	0.1	1.0	-0.3	0.3	-0.1	-0.1	-0.1	0.7	-0.0	-0.3	-0.2	-0.2	0.1	-1.0	-0.0	-0.2	-0.1	-0.2	0.2
Diabetes (mother)	0.1	0.1	0.7	0.1	0.5	-0.8	0.4	0.4	0.2	-0.3	0.0	0.2	0.1	0.1	0.4	0.3	0.3	0.3	0.2	0.3
Townsend deprivation index at recruitment	0.1	0.1	0.5	-0.4	0.1	-0.0	0.4	0.3	0.5	-0.7	-0.4	-0.3	-0.3	0.4	-0.2	0.1	-0.1	-0.1	-0.4	0.4
Current tobacco smoking	0.1	0.2	1.5	-0.1	0.7	0.7	-0.7	0.4	0.1	0.3	-0.1	-0.0	0.0	0.6	-1.2	0.3	0.1	0.1	0.1	0.7
Maternal smoking around birth	0.1	0.2	1.1	-0.1	0.2	1.0	-0.2	0.6	0.4	0.2	0.1	-0.1	0.1	0.7	-1.1	0.0	-0.1	-0.0	-0.0	0.4
Fed-up feelings	0.1	0.2	0.5	-0.6	-0.2	-0.3	-0.0	-0.3	-0.1	-0.7	-0.6	-0.6	-0.6	-0.1	-0.2	-0.3	-0.4	-0.5	-0.6	-0.2
Medication: Levothyroxine sodium	0.1	0.2	1.2	-0.0	0.0	0.3	0.5	0.3	1.1	0.5	0.1	-0.0	0.1	0.6	0.8	0.0	-0.1	0.1	0.0	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.7	0.3	0.2	0.0	-0.1	0.0	-0.8	-0.4	0.2	0.3	0.2	-0.1	0.1	0.4	0.4	0.2	0.3	0.2
Medication: Ramipril	0.1	0.1	0.5	-0.1	0.3	0.1	0.2	0.4	0.4	-0.1	0.2	-0.1	0.1	0.6	-0.7	-0.1	-0.1	-0.1	-0.1	-0.1
Arm fat percentage (right)	0.1	0.3	1.1	0.2	-0.2	0.7	1.1	-0.2	0.7	0.7	0.8	0.2	0.5	0.8	0.6	-0.0	-0.2	0.0	0.2	-0.5
Hip circumference	0.1	0.4	2.4	0.6	-0.3	0.7	1.5	-0.2	-0.0	0.2	1.0	0.6	0.7	0.4	0.9	0.4	0.3	0.3	0.5	-0.5
Falls in the last year	0.1	0.2	0.9	-0.4	-0.5	0.3	-0.1	-0.6	-0.6	-0.1	-0.1	-0.3	-0.2	-0.2	-0.9	-0.5	-0.3	-0.4	-0.3	-0.5
Asthma	0.1	0.1	0.4	0.1	0.6	0.3	0.7	0.4	0.4	-0.5	-0.1	0.0	0.0	0.4	0.3	0.4	0.3	0.2	-0.0	0.4
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.3	0.3	-0.1	-0.5	-0.1	0.0	-0.2	0.3	0.2	0.3	0.2	-0.1	-0.4	0.2	0.4	0.3	0.3	0.2
Glaucoma (self-reported)	0.1	0.1	0.8	0.1	0.3	0.9	0.2	-0.0	0.4	0.3	-0.1	0.1	-0.0	-0.0	0.6	0.2	0.1	0.1	0.1	0.2
Number of full brothers	0.1	0.1	1.1	0.1	0.2	-0.8	-0.4	0.1	-1.0	-0.5	0.1	0.1	0.1	-0.3	-0.3	0.1	0.3	0.1	0.1	-0.1
Worry too long after embarrassment	0.1	0.2	0.9	0.4	0.5	1.0	0.5	-0.2	-0.2	0.1	0.4	0.4	0.4	-0.1	0.0	0.3	0.4	0.3	0.4	0.1
Wheeze or whistling in the chest in last year	0.1	0.1	0.9	-0.0	0.2	0.9	0.5	0.3	0.6	0.3	0.0	-0.1	0.0	0.7	-0.2	0.0	0.0	0.0	-0.0	0.4
Number of children fathered	0.1	0.1	0.3	0.2	0.5	-0.3	-0.0	0.5	0.2	0.0	-0.2	0.1	-0.0	-0.2	0.4	0.2	0.3	0.3	0.2	0.6
Age at first live birth	0.1	0.2	0.5	0.5	0.5	-0.2	-0.2	0.5	0.2	0.7	0.5	0.6	0.5	0.3	-0.1	0.5	0.5	0.5	0.6	0.5
Qualifications: College or University degree	0.1	0.3	1.9	0.1	-0.5	1.4	0.5	-0.6	-0.7	-0.7	0.1	0.1	-0.0	-0.7	0.7	-0.1	-0.1	-0.1	-0.0	-0.8
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.9	-0.2	0.4	0.1	-0.0	0.5	0.7	-0.2	-0.2	-0.2	-0.1	0.5	0.9	-0.0	-0.3	-0.1	-0.2	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.3	0.2	0.1	0.4	0.4	0.5	0.4	-0.4	0.2	0.2	0.2	0.5	0.4	0.4	0.2	0.2	0.1	0.1
Illnesses of siblings: Diabetes	0.1	0.2	0.7	0.3	0.0	0.8	0.7	-0.4	-0.9	-0.5	0.3	0.3	0.2	-0.3	0.1	0.3	0.4	0.2	0.2	-0.2
Arm fat percentage (left)	0.1	0.5	1.5	0.5	0.1	0.7	1.2	0.2	1.0	0.9	1.1	0.5	0.8	1.0	0.6	0.3	0.1	0.3	0.4	-0.2
Long-standing illness, disability or infirmity	0.1	0.2	2.5	0.1	0.2	-0.3	1.6	-0.1	0.2	-0.3	0.2	0.1	0.2	0.6	0.0	0.4	0.4	0.2	0.1	0.2
Qualifications: nursing, teaching	0.1	0.1	0.7	0.3	-0.0	-0.5	-0.2	0.2	-0.9	-0.4	0.1	0.4	0.2	-0.5	-0.1	0.4	0.5	0.3	0.4	0.0
Eye problems/disorders: Cataract	0.1	0.1	0.5	0.1	-0.5	-0.4	-0.1	-0.7	-0.3	0.2	0.0	0.0	-0.0	-0.7	0.3	-0.2	-0.1	-0.1	0.0	-0.7
Asthma (self-reported)	0.1	0.1	0.4	0.1	0.7	0.0	0.6	0.4	0.4	-0.5	-0.1	0.0	0.0	0.3	0.1	0.3	0.3	0.2	-0.0	0.4
Arm fat mass (left)	0.1	0.5	2.4	0.6	-0.2	1.0	1.5	-0.2	0.2	0.5	1.2	0.6	0.8	0.6	0.7	0.4	0.3	0.4	0.6	-0.4
Miserableness	0.1	0.2	0.8	0.5	0.3	0.4	0.6	0.4	-0.2	-0.3	0.5	0.5	0.5	0.5	0.9	0.7	0.6	0.4	0.4	0.3
Medication: Atorvastatin	0.1	0.2	0.9	-0.3	-0.4	-0.4	-0.6	-0.3	-0.9	-0.1	-0.3	-0.2	-0.3	-0.4	-0.5	-0.3	-0.1	-0.3	-0.2	-0.3
Ever depressed for a whole week	0.1	0.1	0.4	-0.2	-0.2	0.6	0.4	-0.6	0.2	0.4	0.0	-0.2	-0.0	0.2	-0.4	-0.2	-0.3	-0.2	-0.1	-0.2
Commuting to job workplace: Cycle	0.1	0.1	0.5	-0.4	-0.2	-0.3	-0.2	0.2	0.7	-0.1	-0.4	-0.4	-0.3	0.2	-0.4	-0.4	-0.4	-0.3	-0.4	0.1
Pain experienced in last month	0.1	0.2	1.2	-0.1	0.2	0.7	-0.3	0.6	-0.1	-1.1	-0.4	-0.1	-0.2	-0.3	0.6	0.3	0.1	0.1	-0.1	0.2
Supplements: Calcium	0.1	0.1	0.6	0.1	0.2	-0.6	0.3	-0.2	0.0	0.3	0.1	0.1	0.1	-0.1	-0.8	-0.1	0.2	0.1	0.1	0.0
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.6	0.2	0.2	-0.6	0.0	-0.1	-0.6	-0.4	0.1	0.1	0.1	-0.4	0.8	0.2	0.2	0.1	0.1	-0.2
Crohns Disease (2012)	0.0	0.0	0.2	0.4	0.3	-0.2	-0.3	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.1
Hair Pigment	0.0	0.6	3.8	0.3	-0.6	1.9	0.5	-1.0	-0.9	-0.0	0.6	0.4	0.4	-0.5	-1.0	0.1	0.1	0.0	0.3	-1.1
Hair/balding pattern: Pattern 4	0.0	0.1	0.3	-0.0	-0.2	0.6	-0.2	-0.3	-0.6	-0.4	-0.1	-0.0	-0.1	-0.5	0.5	0.0	-0.1	-0.1	-0.0	-0.3
Birth weight of first child	0.0	0.1	0.3	-0.2	-0.1	-0.6	-0.1	-0.0	-0.5	-0.4	-0.2	-0.2	-0.2	-0.0	-0.1	-0.1	-0.1	-0.2	-0.2	-0.1
Blood clot in the leg (DVT)	0.0	0.1	0.3	0.2	0.3	-0.5	0.0	0.0	0.0	-0.0	0.1	0.1	0.1	-0.1	0.6	0.2	0.1	0.1	0.1	-0.0
Guilty feelings	0.0	0.1	0.3	0.2	-0.2	-0.6	0.3	-0.1	-0.3	-0.4	0.2	0.2	0.2	-0.0	0.5	0.4	0.2	0.1	0.1	-0.1

Hub : Genes

ZNF559

Models

Trait associations