TWAS hub - SNAPC2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.0542	0.0184	0.0008	0.001	0.004	0.010	0.01	0.006	0.11	0.0110	0.00016	0.00017	0.0026
2	TCGA	Brain Lower Grade Glioma	0.0308	0.0151	0.0012	-0.002	0.014	-0.001	NA	-0.001	0.75	0.0093	0.38000	NA	0.5100

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Type 2 Diabetes (T2D) (2018)	5.3	9.9	17.1	1.7	4.1
Diabetes (self-reported)	5.2	8.0	14.1	1.4	3.8
Diabetes diagnosed by doctor	4.5	7.4	13.1	1.4	3.6
Diabetes (father)	4.3	5.4	10.7	-0.1	3.3
Falls in the last year	4.0	5.4	10.8	3.3	-0.2
Ever had hysterectomy (womb removed)	3.9	4.4	7.3	1.2	2.7
Chronic bronchitis/emphysema (mother)	3.8	4.5	6.9	-2.6	-1.4
Triglycerides	3.7	6.1	10.1	-1.4	3.2
Ever highly irritable/argumentative for 2 days	3.4	4.1	5.5	1.6	2.3
Impedance of arm (right)	3.2	15.0	29.8	-0.5	-5.5
Severe depression (siblings)	3.0	3.4	3.6	-1.9	-1.8
Impedance of arm (left)	3.0	13.9	27.6	-0.4	-5.3
Worry (Nagel 2018)	2.7	5.7	8.0	2.8	-1.9
Medication: Metformin	2.7	3.8	6.5	1.1	2.6
Illnesses of father: None of the above (group 1)	2.6	3.2	4.2	-2.0	-1.5
Eye problems/disorders: Glaucoma	2.6	3.1	4.6	-2.1	1.3
Nervous feelings	2.5	4.7	6.2	2.5	-1.8
Length of working week for main job	2.5	2.7	4.4	2.1	-1.0
Suffer from ‘nerves’	2.5	3.9	5.9	2.4	-1.4
Neuroticism (Nagel 2018)	2.4	5.5	7.6	2.8	-1.9
HDL Cholesterol	2.4	4.0	6.4	1.3	-2.5
Peak expiratory flow (PEF)	2.4	5.5	9.5	3.1	1.2
Hand grip strength (right)	2.3	6.3	10.8	3.3	1.4
Glaucoma (self-reported)	2.3	2.7	3.0	-1.7	1.6
Neuroticism	2.2	5.3	7.4	2.7	-1.8
Medication: Lisinopril	2.2	2.9	4.5	-1.1	2.1
Hearing difficulty/problems: Yes	2.1	3.3	6.0	2.4	0.7
Diverticular disease/diverticulitis (self-reported)	2.1	2.5	5.0	0.2	2.2
Medication: Aspirin	2.0	2.6	4.9	-0.5	2.2
Fed-up feelings	1.9	3.5	3.9	2.0	-1.8
Number of children fathered	1.9	2.2	4.3	2.1	-0.2
Mouth/teeth dental problems: Loose teeth	1.9	2.2	3.7	-1.9	0.8
Depression (Nagel 2018)	1.8	2.7	5.2	2.3	-0.4
Neuroticism (2016)	1.8	2.6	5.2	2.3	0.0
Ever depressed for a whole week	1.8	2.2	2.9	-1.2	-1.7
Impedance of whole body	1.8	8.9	17.6	-0.5	-4.2
Medication: Amlodipine	1.7	2.3	2.9	1.7	1.3
Mouth/teeth dental problems: Bleeding gums	1.6	2.0	2.1	1.4	1.5
Medication: Aspirin	1.6	2.1	3.9	-0.6	2.0
Type 2 Diabetes (T2D) (2012)	1.5	1.7	2.1	-1.4	1.2
Diabetes (mother)	1.5	1.9	3.7	1.9	0.4
Neuroticism score	1.5	3.1	3.4	1.8	-1.7
Alcohol intake versus 10 years previously	1.5	2.2	4.1	-2.0	0.6
Arm fat-free mass (right)	1.5	7.5	14.4	0.7	3.8
Worry too long after embarrassment	1.5	2.5	4.1	0.9	-2.0
Medication: Ibuprofen	1.5	1.8	3.6	-0.3	-1.9
Wears glasses or contact lenses	1.5	1.7	3.4	1.8	-0.1
Mother’s age at death	1.5	1.9	3.8	1.9	-0.3
Arm fat-free mass (left)	1.5	7.4	14.0	0.9	3.7
Number of operations (self-reported)	1.5	2.3	3.9	-0.8	2.0
Eye problems/disorders: Diabetes related eye disease	1.4	1.6	3.2	-0.1	1.8
Trunk fat-free mass	1.4	8.3	14.3	1.5	3.8
Trunk predicted mass	1.4	8.2	14.4	1.5	3.8
Arm predicted mass (right)	1.4	7.0	13.6	0.7	3.7
Medication: Gliclazide	1.4	1.6	2.3	1.5	1.0
Commuting to job workplace: Public transport	1.4	1.7	2.0	1.2	-1.4
Cholesterol lowering medication	1.4	2.1	3.5	0.9	1.9
Fasting Glucose	1.3	1.5	2.2	-1.5	1.0
Hand grip strength (left)	1.3	3.4	6.8	2.6	-0.4
Average weekly spirits intake	1.3	1.6	1.9	1.1	-1.4
Forced expiratory volume in 1-second (FEV1)	1.3	4.4	4.7	2.2	2.0
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	3.4	-1.9	-0.9
Illnesses of father: High blood pressure	1.3	1.6	2.4	1.6	0.8
Irritability	1.3	2.2	2.3	1.5	-1.5
Ovarian Cancer	1.2	1.6	2.5	-1.6	0.8
Body Mass Index (BMI) (2010)	1.2	1.7	2.1	-1.1	1.4
Forced vital capacity (FVC)	1.2	4.6	4.6	2.1	2.1
Number of live births	1.2	1.7	3.0	-0.6	1.7
Qualifications: A levels/AS levels or equivalent	1.2	2.7	3.8	1.3	-2.0
Family relationship satisfaction	1.2	1.4	2.7	1.7	-0.3
Whole body fat-free mass	1.2	7.0	12.6	1.2	3.5
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	2.5	1.6	-0.3
Whole body water mass	1.2	6.8	12.3	1.2	3.5
Basal metabolic rate	1.2	6.4	11.3	1.2	3.4
Myopia	1.2	1.8	3.5	1.9	-0.3
Arm predicted mass (left)	1.2	6.0	11.5	0.8	3.4
Crohns Disease (2012)	1.1	1.7	3.3	-0.3	-1.8
LDL Cholesterol	1.1	1.7	2.4	1.6	-1.0
Pack years adult smoking proportion	1.1	1.6	2.0	1.4	-1.1
Serious illness, injury or assault to yourself	1.1	1.3	2.6	0.2	1.6
Heart attack	1.1	1.4	2.8	-1.7	0.1
Medication: Simvastatin	1.1	1.6	3.1	-0.1	1.8
Hair/balding pattern: Pattern 3	1.1	1.6	3.2	1.8	-0.0
Medication: Cholesterol lowering	1.1	1.7	3.4	-0.1	1.9
Birth weight of first child	1.1	2.1	3.7	0.6	1.9
Health satisfaction	1.1	1.4	2.6	1.6	0.5
Mean time to correctly identify matches	1.1	2.1	2.9	-1.2	1.7
Leg pain on walking	1.1	1.4	2.8	1.7	0.1
Supplements: Vitamin C	1.1	1.3	1.8	0.9	-1.3
Leg fat-free mass (right)	1.1	5.6	9.7	1.2	3.1
Ever had bowel cancer screening	1.1	1.3	1.3	-1.1	1.1
Supplements: Fish oil (including cod liver oil)	1.1	1.5	1.6	-1.2	-1.2
Ever had prostate specific antigen (PSA) test	1.1	1.3	1.9	0.8	1.4
Age at First Birth	1.0	1.4	2.4	-1.5	-0.6
Schizophrenia (2014)	1.0	2.2	4.2	0.4	-2.0
BMI	1.0	5.6	11.2	0.1	3.4
Other serious medical condition/disability diagnosed by doctor	1.0	1.4	2.7	0.1	1.6
Maternal smoking around birth	1.0	1.4	2.0	-0.9	1.4
Gout (self-reported)	1.0	1.3	2.4	-0.5	1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.4	1.5	1.1	-1.2
Shortness of breath walking on level ground	1.0	1.2	2.4	0.2	-1.6
Illnesses of siblings: Diabetes	1.0	1.3	2.5	-0.2	1.6
Handedness (chirality/laterality): Left-handed	1.0	1.2	2.1	-0.6	-1.5
Leg predicted mass (right)	1.0	5.3	9.2	1.2	3.0
Risk taking	1.0	1.4	2.5	0.5	-1.6
Commuting to job workplace: Cycle	1.0	1.2	1.4	1.2	1.0
Cardiovascular Disease	0.9	3.0	5.8	0.4	2.4
Angina	0.9	1.1	2.3	-0.0	1.5
Medication for hormone replacement therapy	0.9	1.0	2.1	-1.4	0.0
Medication: Levothyroxine sodium	0.9	1.5	2.5	1.6	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	1.7	1.3	1.1
Hearing difficulty/problems with background noise	0.9	1.5	2.0	1.4	-0.9
Pain all over the body in last month	0.9	1.0	2.0	-0.0	-1.4
Time employed in main current job	0.9	1.0	1.6	-1.3	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	1.7	-1.1	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	2.2	0.5	-1.5
Medication: Allopurinol	0.9	1.2	2.5	-0.2	1.6
Mineral and other dietary supplements	0.9	1.2	1.4	1.2	1.0
Smoking status: Current	0.9	1.5	3.0	1.7	-0.0
Ever taken oral contraceptive pill	0.9	1.0	1.5	0.7	1.2
Tinnitus: Yes, now most or all of the time	0.9	1.1	1.7	1.3	-0.7
Supplements: Calcium	0.9	1.0	1.7	-1.3	-0.5
Depressed Affect (Nagel 2018)	0.8	1.7	2.8	1.7	-0.8
Schizophrenia (2018)	0.8	1.6	3.0	-0.5	-1.7
Mean Putamen Volume	0.8	0.9	1.4	0.6	-1.2
Leg fat-free mass (left)	0.8	4.4	7.7	1.1	2.8
Current tobacco smoking	0.8	1.3	2.5	1.6	0.3
Leg predicted mass (left)	0.8	4.5	8.0	1.0	2.8
Prospective memory result	0.8	1.0	1.1	1.0	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.5	2.6	1.5	1.6
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	2.0	0.7	-1.4
High blood pressure (siblings)	0.8	1.1	1.9	-1.4	0.5
Forced vital capacity (FVC), Best measure	0.8	3.0	3.9	2.0	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	1.6	1.3	-0.6
Long-standing illness, disability or infirmity	0.8	1.3	2.3	-0.5	1.5
Back pain experienced in last month	0.8	1.2	1.4	0.9	1.2
Pain type(s) experienced in last month: Hip pain	0.8	1.0	1.9	1.4	-0.4
Average weekly beer plus cider intake	0.8	1.2	2.1	0.6	-1.4
Heart attack/myocardial infarction (self-reported)	0.8	1.0	2.1	-1.4	0.1
Bipolar Disorder or Schizophrenia	0.7	1.6	2.6	-0.8	-1.6
Lung FVC	0.7	3.7	3.9	1.9	2.0
Impedance of leg (right)	0.7	3.5	6.5	-0.6	-2.6
Supplements: Glucosamine	0.7	0.9	1.7	-1.3	0.1
Comparative body size at age 10	0.7	1.9	3.3	0.7	1.8
Eye problems/disorders: Cataract	0.7	0.8	1.6	-1.2	-0.2
Financial situation satisfaction	0.7	0.9	1.0	1.0	-0.9
High cholesterol (Self-reported)	0.7	1.2	2.2	0.3	1.5
Fractured/broken bones in last 5 years	0.7	0.9	1.4	0.6	1.2
Pack years of smoking	0.7	1.1	1.4	0.8	-1.2
Blood White Count	0.6	4.2	4.8	2.2	-1.9
Medication: Atenolol	0.6	0.7	1.3	-1.2	0.2
Number of incorrect matches in round	0.6	1.0	1.4	1.2	-0.8
Medication: Ramipril	0.6	0.7	1.3	-0.3	1.2
Weight	0.6	3.0	4.7	1.1	2.2
Number of full brothers	0.6	0.8	1.5	0.0	1.2
Wheeze or whistling in the chest in last year	0.6	1.2	2.0	0.5	-1.4
Angina (self-reported)	0.6	0.8	1.6	0.1	1.2
Pulse rate, automated reading	0.6	2.1	3.9	2.0	-0.5
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.0	-1.0	0.7
Medication for cholesterol	0.6	0.9	1.4	0.7	-1.2
Ever smoked	0.6	1.1	1.9	1.4	-0.5
Heart disease (siblings)	0.6	0.7	1.1	-0.5	1.1
Crohns Disease (2017)	0.5	1.1	1.7	0.7	-1.3
Ulcerative Colitis (UC)	0.5	1.0	1.6	0.7	1.2
Reaction Time	0.5	1.0	1.3	-0.8	1.2
Smoking Status	0.5	1.2	2.5	1.6	-0.0
Respiratory disease	0.5	1.0	1.8	-0.5	-1.3
Multivitamins +/- minerals	0.5	0.6	0.8	-0.9	0.7
Impedance of leg (left)	0.5	2.4	4.4	-0.6	-2.1
Past tobacco smoking	0.5	0.9	1.5	-1.2	0.5
Mouth/teeth dental problems	0.5	0.8	1.5	-0.3	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.0	-1.0	0.5
Depression (self-reported)	0.5	0.5	1.0	1.0	0.2
Lung cancer (father)	0.5	0.6	1.3	0.1	1.1
Pulse wave Arterial Stiffness index	0.5	0.6	1.1	-0.1	-1.0
Breastfed as a baby	0.5	0.6	1.0	0.4	1.0
Tense / ‘highly strung’	0.5	0.8	1.2	1.1	-0.7
Leg fat mass (right)	0.5	1.9	3.7	0.4	1.9
Number of full sisters	0.5	0.6	1.1	-0.0	1.1
Had major operations	0.5	0.6	1.1	0.4	1.1
Friendships satisfaction	0.5	0.6	1.1	1.0	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	1.9	0.2	1.4
Average weekly champagne plus white wine intake	0.5	0.7	1.0	1.0	-0.6
Miserableness	0.5	0.9	1.6	1.3	0.5
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.1	-0.3	1.1
Leg fat mass (left)	0.5	2.0	3.9	0.3	2.0
Alzheimer’s Disease (in father)	0.4	0.4	0.8	0.9	0.2
Prostate Cancer	0.4	0.5	1.0	-1.0	-0.1
Rheumatoid Arthritis	0.4	0.6	1.2	1.1	0.1
Hypothyroidism (self reported)	0.4	0.9	1.1	1.1	-0.8
Lung FEV1/FVC ratio	0.4	1.9	2.5	1.1	1.6
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.1	1.1	0.3
Relative age of first facial hair	0.4	0.8	0.8	0.9	0.9
Townsend deprivation index at recruitment	0.4	0.5	1.0	1.0	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	1.1	1.1	-0.0
Sitting height	0.4	2.5	3.5	1.9	1.2
High blood pressure (mother)	0.4	0.6	0.9	0.5	1.0
Qualifications: None of the above	0.4	0.8	1.4	-1.2	0.4
Allergy	0.4	0.9	1.8	-1.4	0.0
Illnesses of siblings	0.4	0.6	0.8	0.9	-0.6
Exposure to tobacco smoke at home	0.4	0.5	0.8	-0.4	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.5	1.1	-0.2	1.0
Pulse wave peak to peak time	0.4	0.5	1.0	0.1	1.0
Medication: Blood pressure	0.4	0.7	1.1	-0.7	1.0
Age at last live birth	0.4	0.5	0.9	-0.3	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.0	0.1	1.0
Alzheimer’s Disease (including proxy)	0.3	0.5	1.0	1.0	-0.2
Heel T-Score	0.3	2.5	4.4	-0.8	-2.1
Tanning	0.3	4.0	6.1	-2.5	-1.4
Ever used hormone-replacement therapy (HRT)	0.3	0.3	0.4	-0.6	0.6
Stomach or abdominal pain in last month	0.3	0.4	0.4	-0.6	0.7
Body mass index (BMI)	0.3	1.3	2.5	0.4	1.6
Hair/balding pattern: Pattern 2	0.3	0.4	0.7	-0.8	0.2
Fluid intelligence score	0.3	0.6	1.2	0.0	-1.1
Hip circumference	0.3	1.5	1.7	1.3	1.1
Worrier / anxious feelings	0.3	0.6	1.0	1.0	-0.5
Pulse rate	0.3	0.5	0.5	0.7	-0.7
Illnesses of mother	0.3	0.3	0.6	0.0	0.8
Standing height	0.3	2.9	3.2	1.8	1.6
Hair/balding pattern: Pattern 4	0.3	0.8	1.4	-0.4	-1.2
Headache pain in last month	0.3	0.4	0.7	0.8	-0.4
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	1.3	1.1	0.2
Birth weight	0.3	0.7	1.3	1.1	0.3
Age at first live birth	0.3	0.6	0.8	-0.6	-0.9
Medication: Omeprazole	0.3	0.4	0.8	-0.0	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	0.4	-0.6	0.5
Whole body fat mass	0.3	1.1	2.0	0.4	1.4
Alcohol intake frequency.	0.3	0.7	0.8	-0.8	0.9
Chest pain or discomfort	0.3	0.4	0.4	0.7	-0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.5	-0.4	-0.7
Average weekly red wine intake	0.3	0.5	0.9	0.9	0.4
Commuting to job workplace: Walk	0.3	0.3	0.5	-0.7	0.3
Osteoporosis (self-reported)	0.3	0.3	0.3	-0.6	0.6
Osteoarthritis (self-reported)	0.3	0.4	0.6	0.8	0.5
Number of self-reported non-cancer illnesses	0.3	0.4	0.5	0.7	0.7
Guilty feelings	0.3	0.5	0.8	-0.5	-0.9
Hearing aid user	0.3	0.3	0.4	0.6	0.5
Bipolar Disorder (2018)	0.2	0.4	0.6	-0.8	-0.4
Irritable Bowel Disease (IBD)	0.2	0.4	0.6	0.8	0.4
Verbal and Numeric Reasoning (VNR)	0.2	0.5	0.8	0.5	-0.9
Blood Eosinophil Count	0.2	1.4	2.9	1.7	0.0
Blood Red Count	0.2	1.8	2.9	1.7	0.8
Height	0.2	3.2	3.3	1.8	1.8
Allergy or Eczema	0.2	0.6	0.9	0.5	-1.0
Number of treatments/medications taken	0.2	0.4	0.6	-0.7	0.4
Sensitivity / hurt feelings	0.2	0.4	0.6	0.8	-0.5
Average weekly fortified wine intake	0.2	0.2	0.3	-0.6	-0.3
Taking other prescription medications	0.2	0.4	0.5	0.7	0.4
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	0.2	0.6
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.7	0.9	-0.3
Waist circumference	0.2	0.8	1.3	0.5	1.1
Had menopause	0.2	0.3	0.4	-0.7	0.3
Medication: Lansoprazole	0.2	0.2	0.3	0.6	-0.1
Arm fat mass (right)	0.2	0.7	1.2	0.4	1.1
Pulse wave reflection index	0.2	0.3	0.3	0.5	0.5
Loud music exposure frequency	0.2	0.2	0.3	-0.6	0.3
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.5	0.7	-0.4
Blood clot in the leg (DVT)	0.2	0.2	0.4	-0.1	0.6
Eye problems/disorders: None of the above	0.2	0.3	0.4	0.7	-0.3
Emphysema/chronic bronchitis	0.2	0.2	0.3	0.3	-0.5
Medication for pain relief, constipation, heartburn	0.2	0.3	0.6	0.0	-0.8
Migraine (self-reported)	0.2	0.2	0.4	-0.7	-0.0
Knee pain experienced in last month	0.2	0.3	0.6	0.8	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.5	0.7	0.0
Illnesses of father: Heart disease	0.2	0.2	0.4	-0.2	-0.7
Loneliness, isolation	0.2	0.3	0.4	0.6	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.4	-0.3	0.6
Arm fat mass (left)	0.2	0.7	1.2	0.4	1.1
Medication: Atorvastatin	0.2	0.3	0.4	0.7	0.3
Vascular/heart problems diagnosed by doctor	0.2	0.4	0.8	-0.2	-0.9
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.4	0.5	-0.6
Schizophrenia vs Biploar Disorder	0.1	0.1	0.3	0.0	-0.5
Breast Cancer	0.1	0.1	0.1	-0.3	0.4
HbA1C	0.1	0.1	0.1	0.3	-0.0
Lupus	0.1	0.2	0.3	0.6	-0.2
Primary Biliary Cirrhosis	0.1	0.1	0.2	-0.4	-0.2
Blood Platelet Count	0.1	0.7	1.1	0.5	-1.0
Chronotype (morning person)	0.1	0.3	0.4	0.7	0.4
Hair Pigment	0.1	3.7	7.2	2.7	-0.4
Vitamin and mineral supplements	0.1	0.1	0.2	0.5	0.2
Medication: Co-codamol	0.1	0.1	0.1	0.3	0.3
Age when periods started (menarche)	0.1	0.3	0.4	0.5	0.6
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.2	-0.5	0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.1	0.2	0.2	-0.5
High blood pressure	0.1	0.3	0.4	0.3	0.6
Chronic bronchitis/emphysema (father)	0.1	0.1	0.1	0.3	-0.4
Trunk fat mass	0.1	0.5	0.9	0.3	0.9
Had other major operations	0.1	0.1	0.1	-0.3	0.3
Financial difficulties in last 2 years	0.1	0.2	0.3	0.6	-0.2
Father’s age at death	0.1	0.2	0.3	-0.3	0.6
Happiness	0.1	0.2	0.2	0.4	-0.4
Noisy workplace	0.1	0.1	0.2	-0.3	0.4
Asthma	0.1	0.1	0.2	0.2	-0.4
Leg fat percentage (right)	0.1	0.2	0.4	0.1	0.6
Exposure to tobacco smoke outside home	0.1	0.2	0.3	-0.5	-0.3
Qualifications: College or University degree	0.1	0.3	0.4	0.7	-0.3
Neck or shoulder pain in last month	0.1	0.1	0.3	-0.5	0.1
Medication: Seretide 50 evohaler	0.1	0.1	0.1	-0.1	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	-0.4	0.2
Hypertension (Self-reported)	0.1	0.2	0.3	0.3	0.5
Mood swings	0.1	0.2	0.2	0.5	-0.4
Qualifications: nursing, teaching	0.1	0.1	0.1	0.3	0.3
Breast cancer (self-reported)	0.1	0.1	0.1	0.3	-0.3
Asthma (self-reported)	0.1	0.3	0.6	0.2	-0.7
Medication: Bendroflumethiazide	0.1	0.1	0.1	-0.4	0.2
Alcohol drinker status: Never	0.1	0.1	0.2	0.3	-0.4
Leg fat percentage (left)	0.1	0.5	1.0	0.2	1.0
Age started oral contraceptive pill	0.1	0.1	0.2	-0.2	-0.4
Diastolic blood pressure, automated reading	0.1	0.2	0.2	0.5	0.4
Alcohol drinker status: Previous	0.1	0.1	0.2	-0.0	0.5
Alzheimer’s Disease (in mother)	0.0	0.1	0.1	0.3	-0.2
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	-0.0	0.0
Waist Hip Ratio (WHR)	0.0	0.2	0.3	-0.6	0.1
Systolic Blood Pressure	0.0	0.2	0.3	0.5	0.1
Systolic blood pressure, automated reading	0.0	0.1	0.1	-0.4	0.0
Supplements: Zinc	0.0	0.0	0.1	0.3	-0.0
Trunk fat percentage	0.0	0.0	0.0	-0.2	-0.2
Relative age voice broke	0.0	0.1	0.1	-0.3	0.2
Qualifications: CSEs or equivalent	0.0	0.0	0.0	-0.2	-0.2
Alcohol usually taken with meals	0.0	0.1	0.1	-0.3	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.1	-0.3	-0.2
Ever unenthusiastic/disinterested for a whole week	0.0	0.0	0.0	0.2	-0.2
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.1	-0.2	0.2
Arm fat percentage (right)	0.0	0.1	0.2	-0.1	-0.4
Mouth/teeth dental problems: Dentures	0.0	0.0	0.1	0.2	0.1
Medication: Paracetamol	0.0	0.1	0.1	0.0	0.4
Medication: Ventolin 100micrograms inhaler	0.0	0.0	0.0	0.1	-0.2
Body fat percentage	0.0	0.0	0.1	-0.1	0.2
Heart disease (mother)	0.0	0.0	0.1	-0.3	-0.1
Comparative height size at age 10	0.0	0.3	0.4	0.7	0.3
Overall health rating	0.0	0.0	0.0	-0.1	-0.0
Smoking status: Previous	0.0	0.0	0.0	-0.0	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.1	0.1	0.1	-0.3
Arm fat percentage (left)	0.0	0.1	0.1	0.1	-0.4
Medication: Blood pressure	0.0	0.0	0.0	-0.0	-0.0
Medication: Paracetamol	0.0	0.0	0.1	-0.1	-0.3
Unable to work because of sickness or disability	0.0	0.0	0.0	0.1	0.0
Pain experienced in last month	0.0	0.0	0.1	-0.1	-0.3
Basal cell carcinoma (self-reported)	0.0	0.0	0.0	0.1	0.1

Hub : Genes

SNAPC2

Models

Trait associations