[Hub]/) : Traits : Arm fat percentage (right) :

chr12:120,955,578-125,270,773

Best TWAS P=7.63e-32 · Best GWAS P=1.54e-22 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HIP1R 0.06 0.02 lasso 6 0.04 1.9e-05 -5.6 -5.5 4.2e-08 0.01 0.18 0.02 FALSE
2 GTEx Adipose Subcutaneous CCDC92 0.23 0.04 enet 27 0.16 6.9e-13 -6.3 10.6 1.9e-26 0.48 0.15 0.85 FALSE
3 GTEx Adipose Subcutaneous RP11-380L11.3 0.09 0.03 lasso 3 0.03 1.4e-03 9.4 11.7 1.5e-31 0.87 0.02 0.97 FALSE
4 GTEx Adipose Subcutaneous RP11-380L11.4 0.08 0.06 lasso 4 0.04 1.9e-04 5.8 5.2 1.8e-07 0.58 0.14 0.84 FALSE
5 GTEx Adipose Visceral Omentum CCDC92 0.19 0.02 lasso 8 0.09 3.3e-05 9.5 11.5 8.0e-31 0.63 0.04 0.95 TRUE
6 GTEx Adipose Visceral Omentum RP11-380L11.3 0.15 0.03 lasso 5 0.01 1.4e-01 7.4 11.7 7.6e-32 0.65 0.04 0.76 TRUE
7 GTEx Artery Aorta P2RX4 0.20 0.03 enet 28 0.05 1.6e-03 -3.6 -5.1 2.9e-07 0.04 0.03 0.90 TRUE
8 GTEx Artery Tibial PITPNM2 0.11 0.05 lasso 4 0.04 2.7e-04 -5.5 6.1 1.3e-09 0.06 0.70 0.02 FALSE
9 GTEx Artery Tibial RP11-380L11.4 0.14 0.12 lasso 4 0.12 2.2e-09 9.4 9.3 1.4e-20 0.95 0.04 0.96 TRUE
10 GTEx Brain Putamen basal ganglia WDR66 0.25 0.01 enet 16 -0.01 5.6e-01 5.3 -5.4 8.6e-08 0.01 0.06 0.25 FALSE
11 GTEx Breast Mammary Tissue (Male) CCDC92 0.06 -0.01 lasso 3 0.00 4.3e-01 8.5 9.0 2.3e-19 0.85 0.04 0.14 FALSE
12 GTEx Breast Mammary Tissue (Female) KDM2B 0.13 0.00 lasso 3 0.01 1.2e-01 -4.0 5.1 2.9e-07 0.10 0.05 0.06 TRUE
13 GTEx Breast Mammary Tissue (Female) CCDC92 0.05 -0.01 enet 2 -0.01 6.2e-01 8.4 8.4 3.8e-17 0.89 0.04 0.25 TRUE
14 GTEx Breast Mammary Tissue (Female) C12orf65 0.06 0.00 enet 13 -0.01 6.5e-01 -3.8 -5.3 1.3e-07 -0.08 0.04 0.22 FALSE
15 GTEx Cells Transformed fibroblasts BCL7A 0.06 0.01 lasso 4 0.01 3.1e-02 4.7 -7.3 3.7e-13 -0.04 0.09 0.05 TRUE
16 GTEx Cells Transformed fibroblasts CCDC92 0.09 0.00 enet 28 0.01 3.8e-02 7.6 6.2 4.8e-10 0.40 0.07 0.25 FALSE
17 GTEx Colon Sigmoid RP11-380L11.4 0.21 0.12 lasso 3 0.08 1.1e-03 9.4 9.4 7.1e-21 0.91 0.04 0.89 FALSE
18 GTEx Colon Transverse MLXIP 0.20 0.18 enet 23 0.14 5.8e-07 5.6 5.3 9.7e-08 -0.08 1.00 0.00 FALSE
19 GTEx Colon Transverse SNRNP35 0.18 0.02 lasso 8 0.04 6.5e-03 -3.8 6.9 4.2e-12 0.15 0.08 0.07 TRUE
20 GTEx Esophagus Mucosa KDM2B 0.11 0.04 enet 22 0.10 4.1e-07 3.3 6.7 2.1e-11 0.04 0.86 0.07 TRUE
21 GTEx Esophagus Mucosa CCDC92 0.11 0.02 lasso 4 0.02 1.9e-02 8.6 8.7 2.5e-18 0.89 0.09 0.81 FALSE
22 GTEx Esophagus Mucosa HIP1R 0.21 0.05 lasso 5 0.07 1.5e-05 4.0 7.3 3.5e-13 -0.05 0.47 0.26 TRUE
23 GTEx Esophagus Muscularis RP11-380L11.4 0.27 0.29 lasso 8 0.27 1.0e-16 9.4 9.4 4.3e-21 0.94 0.04 0.96 FALSE
24 GTEx Heart Atrial Appendage CCDC92 0.12 0.11 enet 9 0.11 1.1e-05 6.7 8.9 6.6e-19 0.79 0.06 0.92 FALSE
25 GTEx Heart Atrial Appendage RP11-380L11.4 0.18 0.11 lasso 7 0.12 6.5e-06 9.5 10.2 2.1e-24 0.92 0.03 0.96 FALSE
26 GTEx Heart Left Ventricle CCDC92 0.26 0.19 lasso 4 0.21 1.9e-11 8.6 10.1 8.8e-24 0.87 0.09 0.91 FALSE
27 GTEx Lung CCDC92 0.14 0.00 enet 10 0.01 1.1e-01 8.2 8.3 6.9e-17 0.18 0.18 0.11 TRUE
28 GTEx Lung RP11-380L11.4 0.07 0.07 lasso 3 0.07 8.2e-06 9.5 9.4 7.7e-21 0.94 0.03 0.97 FALSE
29 GTEx Muscle Skeletal RSRC2 0.06 0.03 enet 7 0.04 9.6e-05 -2.4 -5.2 1.7e-07 -0.03 0.25 0.48 FALSE
30 GTEx Muscle Skeletal RP11-380L11.4 0.14 0.03 lasso 8 0.03 4.0e-04 9.4 7.7 1.9e-14 0.90 0.02 0.97 FALSE
31 GTEx Nerve Tibial CCDC92 0.16 0.01 enet 6 0.04 6.7e-04 8.2 9.6 1.1e-21 0.68 0.07 0.64 FALSE
32 GTEx Nerve Tibial KNTC1 0.12 0.05 lasso 5 0.05 1.9e-04 -5.8 -6.2 5.3e-10 0.02 0.53 0.03 FALSE
33 GTEx Prostate CCDC92 0.31 0.10 enet 42 0.11 9.0e-04 8.4 7.0 2.6e-12 0.48 0.06 0.75 FALSE
34 GTEx Skin Sun Exposed Lower leg DDX55 0.13 0.05 enet 13 0.10 1.6e-08 -3.4 5.1 2.9e-07 0.07 1.00 0.00 FALSE
35 GTEx Skin Sun Exposed Lower leg CCDC92 0.11 0.00 enet 15 0.01 1.0e-01 7.6 6.8 1.0e-11 0.50 0.07 0.47 FALSE
36 GTEx Skin Sun Exposed Lower leg RP11-380L11.4 0.04 0.02 enet 15 0.02 1.9e-02 9.5 8.3 7.3e-17 0.83 0.02 0.96 FALSE
37 GTEx Thyroid CCDC92 0.06 0.03 lasso 3 0.02 1.1e-02 9.4 10.4 1.6e-25 0.89 0.03 0.94 FALSE
38 GTEx Thyroid ZNF664 0.13 0.06 lasso 11 0.08 6.7e-07 8.4 -9.2 4.3e-20 -0.87 0.05 0.95 FALSE
39 GTEx Whole Blood DDX55 0.13 0.04 enet 13 0.06 3.3e-06 -3.3 5.4 5.5e-08 0.05 0.34 0.02 FALSE
40 METSIM Adipose ABCB9 0.04 0.03 enet 19 0.03 7.7e-05 -5.6 -7.1 1.1e-12 0.12 0.08 0.65 FALSE
41 METSIM Adipose CCDC92 0.10 0.01 bslmm 435 0.06 5.5e-10 -4.0 10.5 8.4e-26 0.62 0.17 0.83 FALSE
42 METSIM Adipose DNAH10 0.03 0.00 bslmm 475 0.01 3.2e-03 9.8 8.3 9.1e-17 0.66 0.01 0.92 FALSE
43 METSIM Adipose MORN3 0.06 0.02 lasso 10 0.04 8.7e-07 5.1 6.2 7.5e-10 0.01 0.75 0.21 FALSE
44 METSIM Adipose RP11-214K3.24 0.05 0.03 bslmm 444 0.02 2.7e-04 8.6 10.1 8.1e-24 0.73 0.04 0.92 FALSE
45 NTR Blood ZNF664 0.02 0.00 bslmm 447 0.01 6.3e-04 -4.6 -5.7 1.5e-08 -0.57 0.03 0.84 FALSE
46 The Cancer Genome Atlas Breast Invasive Carcinoma DNAH10 0.11 0.03 blup 99 0.05 8.2e-11 7.0 8.8 1.4e-18 0.71 0.04 0.96 FALSE
47 The Cancer Genome Atlas Colon Adenocarcinoma MLXIP 0.06 0.04 lasso 7 0.02 2.7e-02 5.4 5.5 2.9e-08 -0.07 0.03 0.90 FALSE
48 The Cancer Genome Atlas Glioblastoma Multiforme CCDC92 0.07 0.02 blup 52 0.04 1.8e-02 8.4 8.9 7.2e-19 0.93 0.02 0.73 FALSE
49 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DNAH10 0.10 0.01 blup 98 0.02 3.7e-03 9.5 5.5 3.1e-08 0.64 0.03 0.83 TRUE
50 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC92 0.06 0.04 enet 8 0.05 1.7e-06 8.6 6.4 2.1e-10 0.75 0.06 0.91 FALSE
51 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DNAH10 0.07 0.03 lasso 3 0.05 7.4e-06 9.5 9.2 3.7e-20 0.80 0.02 0.97 FALSE
52 The Cancer Genome Atlas Rectum Adenocarcinoma MLXIP 0.18 0.14 lasso 4 0.13 5.1e-04 4.8 5.2 2.2e-07 -0.08 0.03 0.84 FALSE
53 The Cancer Genome Atlas Soft Tissue Sarcoma CCDC92 0.05 0.03 blup 52 0.03 5.8e-03 4.0 7.4 1.4e-13 0.91 0.04 0.66 FALSE
54 The Cancer Genome Atlas Stomach Adenocarcinoma MLXIP 0.06 0.02 blup 68 0.04 1.2e-03 5.5 6.9 3.9e-12 -0.03 0.03 0.81 TRUE
55 The Cancer Genome Atlas Thyroid Carcinoma DNAH10 0.04 0.03 lasso 5 0.02 4.6e-03 8.2 8.6 7.0e-18 0.86 0.01 0.87 FALSE
56 The Cancer Genome Atlas Thyroid Carcinoma VPS33A 0.06 0.00 enet 8 0.03 9.6e-04 4.8 -5.7 1.1e-08 0.02 0.12 0.86 FALSE
57 The Cancer Genome Atlas Thyroid Carcinoma ZNF664 0.06 0.05 enet 9 0.05 2.8e-05 9.4 -9.7 4.4e-22 -0.92 0.03 0.97 FALSE