[Hub]/) : Traits : Arm fat percentage (right) : ← →

chr12:120,955,578-125,270,773

Best TWAS P=7.63e-32 · Best GWAS P=1.54e-22 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Adipose Visceral Omentum	RP11-380L11.3	0.15	0.03	lasso	5	0.01	1.4e-01	7.4	11.7	7.6e-32	0.65	0.04	0.76	TRUE
5	GTEx	Adipose Visceral Omentum	CCDC92	0.19	0.02	lasso	8	0.09	3.3e-05	9.5	11.5	8.0e-31	0.63	0.04	0.95	TRUE
9	GTEx	Artery Tibial	RP11-380L11.4	0.14	0.12	lasso	4	0.12	2.2e-09	9.4	9.3	1.4e-20	0.95	0.04	0.96	TRUE
13	GTEx	Breast Mammary Tissue (Female)	CCDC92	0.05	-0.01	enet	2	-0.01	6.2e-01	8.4	8.4	3.8e-17	0.89	0.04	0.25	TRUE
27	GTEx	Lung	CCDC92	0.14	0.00	enet	10	0.01	1.1e-01	8.2	8.3	6.9e-17	0.18	0.18	0.11	TRUE
22	GTEx	Esophagus Mucosa	HIP1R	0.21	0.05	lasso	5	0.07	1.5e-05	4.0	7.3	3.5e-13	-0.05	0.47	0.26	TRUE
15	GTEx	Cells Transformed fibroblasts	BCL7A	0.06	0.01	lasso	4	0.01	3.1e-02	4.7	-7.3	3.7e-13	-0.04	0.09	0.05	TRUE
54	The Cancer Genome Atlas	Stomach Adenocarcinoma	MLXIP	0.06	0.02	blup	68	0.04	1.2e-03	5.5	6.9	3.9e-12	-0.03	0.03	0.81	TRUE
19	GTEx	Colon Transverse	SNRNP35	0.18	0.02	lasso	8	0.04	6.5e-03	-3.8	6.9	4.2e-12	0.15	0.08	0.07	TRUE
20	GTEx	Esophagus Mucosa	KDM2B	0.11	0.04	enet	22	0.10	4.1e-07	3.3	6.7	2.1e-11	0.04	0.86	0.07	TRUE
49	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DNAH10	0.10	0.01	blup	98	0.02	3.7e-03	9.5	5.5	3.1e-08	0.64	0.03	0.83	TRUE
7	GTEx	Artery Aorta	P2RX4	0.20	0.03	enet	28	0.05	1.6e-03	-3.6	-5.1	2.9e-07	0.04	0.03	0.90	TRUE
12	GTEx	Breast Mammary Tissue (Female)	KDM2B	0.13	0.00	lasso	3	0.01	1.2e-01	-4.0	5.1	2.9e-07	0.10	0.05	0.06	TRUE
3	GTEx	Adipose Subcutaneous	RP11-380L11.3	0.09	0.03	lasso	3	0.03	1.4e-03	9.4	11.7	1.5e-31	0.87	0.02	0.97	FALSE
2	GTEx	Adipose Subcutaneous	CCDC92	0.23	0.04	enet	27	0.16	6.9e-13	-6.3	10.6	1.9e-26	0.48	0.15	0.85	FALSE
41	METSIM	Adipose	CCDC92	0.10	0.01	bslmm	435	0.06	5.5e-10	-4.0	10.5	8.4e-26	0.62	0.17	0.83	FALSE
37	GTEx	Thyroid	CCDC92	0.06	0.03	lasso	3	0.02	1.1e-02	9.4	10.4	1.6e-25	0.89	0.03	0.94	FALSE
25	GTEx	Heart Atrial Appendage	RP11-380L11.4	0.18	0.11	lasso	7	0.12	6.5e-06	9.5	10.2	2.1e-24	0.92	0.03	0.96	FALSE
44	METSIM	Adipose	RP11-214K3.24	0.05	0.03	bslmm	444	0.02	2.7e-04	8.6	10.1	8.1e-24	0.73	0.04	0.92	FALSE
26	GTEx	Heart Left Ventricle	CCDC92	0.26	0.19	lasso	4	0.21	1.9e-11	8.6	10.1	8.8e-24	0.87	0.09	0.91	FALSE
57	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF664	0.06	0.05	enet	9	0.05	2.8e-05	9.4	-9.7	4.4e-22	-0.92	0.03	0.97	FALSE
31	GTEx	Nerve Tibial	CCDC92	0.16	0.01	enet	6	0.04	6.7e-04	8.2	9.6	1.1e-21	0.68	0.07	0.64	FALSE
23	GTEx	Esophagus Muscularis	RP11-380L11.4	0.27	0.29	lasso	8	0.27	1.0e-16	9.4	9.4	4.3e-21	0.94	0.04	0.96	FALSE
17	GTEx	Colon Sigmoid	RP11-380L11.4	0.21	0.12	lasso	3	0.08	1.1e-03	9.4	9.4	7.1e-21	0.91	0.04	0.89	FALSE
28	GTEx	Lung	RP11-380L11.4	0.07	0.07	lasso	3	0.07	8.2e-06	9.5	9.4	7.7e-21	0.94	0.03	0.97	FALSE
51	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DNAH10	0.07	0.03	lasso	3	0.05	7.4e-06	9.5	9.2	3.7e-20	0.80	0.02	0.97	FALSE
38	GTEx	Thyroid	ZNF664	0.13	0.06	lasso	11	0.08	6.7e-07	8.4	-9.2	4.3e-20	-0.87	0.05	0.95	FALSE
11	GTEx	Breast Mammary Tissue (Male)	CCDC92	0.06	-0.01	lasso	3	0.00	4.3e-01	8.5	9.0	2.3e-19	0.85	0.04	0.14	FALSE
24	GTEx	Heart Atrial Appendage	CCDC92	0.12	0.11	enet	9	0.11	1.1e-05	6.7	8.9	6.6e-19	0.79	0.06	0.92	FALSE
48	The Cancer Genome Atlas	Glioblastoma Multiforme	CCDC92	0.07	0.02	blup	52	0.04	1.8e-02	8.4	8.9	7.2e-19	0.93	0.02	0.73	FALSE
46	The Cancer Genome Atlas	Breast Invasive Carcinoma	DNAH10	0.11	0.03	blup	99	0.05	8.2e-11	7.0	8.8	1.4e-18	0.71	0.04	0.96	FALSE
21	GTEx	Esophagus Mucosa	CCDC92	0.11	0.02	lasso	4	0.02	1.9e-02	8.6	8.7	2.5e-18	0.89	0.09	0.81	FALSE
55	The Cancer Genome Atlas	Thyroid Carcinoma	DNAH10	0.04	0.03	lasso	5	0.02	4.6e-03	8.2	8.6	7.0e-18	0.86	0.01	0.87	FALSE
36	GTEx	Skin Sun Exposed Lower leg	RP11-380L11.4	0.04	0.02	enet	15	0.02	1.9e-02	9.5	8.3	7.3e-17	0.83	0.02	0.96	FALSE
42	METSIM	Adipose	DNAH10	0.03	0.00	bslmm	475	0.01	3.2e-03	9.8	8.3	9.1e-17	0.66	0.01	0.92	FALSE
30	GTEx	Muscle Skeletal	RP11-380L11.4	0.14	0.03	lasso	8	0.03	4.0e-04	9.4	7.7	1.9e-14	0.90	0.02	0.97	FALSE
53	The Cancer Genome Atlas	Soft Tissue Sarcoma	CCDC92	0.05	0.03	blup	52	0.03	5.8e-03	4.0	7.4	1.4e-13	0.91	0.04	0.66	FALSE
40	METSIM	Adipose	ABCB9	0.04	0.03	enet	19	0.03	7.7e-05	-5.6	-7.1	1.1e-12	0.12	0.08	0.65	FALSE
33	GTEx	Prostate	CCDC92	0.31	0.10	enet	42	0.11	9.0e-04	8.4	7.0	2.6e-12	0.48	0.06	0.75	FALSE
35	GTEx	Skin Sun Exposed Lower leg	CCDC92	0.11	0.00	enet	15	0.01	1.0e-01	7.6	6.8	1.0e-11	0.50	0.07	0.47	FALSE
50	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CCDC92	0.06	0.04	enet	8	0.05	1.7e-06	8.6	6.4	2.1e-10	0.75	0.06	0.91	FALSE
16	GTEx	Cells Transformed fibroblasts	CCDC92	0.09	0.00	enet	28	0.01	3.8e-02	7.6	6.2	4.8e-10	0.40	0.07	0.25	FALSE
32	GTEx	Nerve Tibial	KNTC1	0.12	0.05	lasso	5	0.05	1.9e-04	-5.8	-6.2	5.3e-10	0.02	0.53	0.03	FALSE
43	METSIM	Adipose	MORN3	0.06	0.02	lasso	10	0.04	8.7e-07	5.1	6.2	7.5e-10	0.01	0.75	0.21	FALSE
8	GTEx	Artery Tibial	PITPNM2	0.11	0.05	lasso	4	0.04	2.7e-04	-5.5	6.1	1.3e-09	0.06	0.70	0.02	FALSE
56	The Cancer Genome Atlas	Thyroid Carcinoma	VPS33A	0.06	0.00	enet	8	0.03	9.6e-04	4.8	-5.7	1.1e-08	0.02	0.12	0.86	FALSE
45	NTR	Blood	ZNF664	0.02	0.00	bslmm	447	0.01	6.3e-04	-4.6	-5.7	1.5e-08	-0.57	0.03	0.84	FALSE
47	The Cancer Genome Atlas	Colon Adenocarcinoma	MLXIP	0.06	0.04	lasso	7	0.02	2.7e-02	5.4	5.5	2.9e-08	-0.07	0.03	0.90	FALSE
1	CommonMind	Brain Pre-frontal Cortex	HIP1R	0.06	0.02	lasso	6	0.04	1.9e-05	-5.6	-5.5	4.2e-08	0.01	0.18	0.02	FALSE
39	GTEx	Whole Blood	DDX55	0.13	0.04	enet	13	0.06	3.3e-06	-3.3	5.4	5.5e-08	0.05	0.34	0.02	FALSE
10	GTEx	Brain Putamen basal ganglia	WDR66	0.25	0.01	enet	16	-0.01	5.6e-01	5.3	-5.4	8.6e-08	0.01	0.06	0.25	FALSE
18	GTEx	Colon Transverse	MLXIP	0.20	0.18	enet	23	0.14	5.8e-07	5.6	5.3	9.7e-08	-0.08	1.00	0.00	FALSE
14	GTEx	Breast Mammary Tissue (Female)	C12orf65	0.06	0.00	enet	13	-0.01	6.5e-01	-3.8	-5.3	1.3e-07	-0.08	0.04	0.22	FALSE
29	GTEx	Muscle Skeletal	RSRC2	0.06	0.03	enet	7	0.04	9.6e-05	-2.4	-5.2	1.7e-07	-0.03	0.25	0.48	FALSE
4	GTEx	Adipose Subcutaneous	RP11-380L11.4	0.08	0.06	lasso	4	0.04	1.9e-04	5.8	5.2	1.8e-07	0.58	0.14	0.84	FALSE
52	The Cancer Genome Atlas	Rectum Adenocarcinoma	MLXIP	0.18	0.14	lasso	4	0.13	5.1e-04	4.8	5.2	2.2e-07	-0.08	0.03	0.84	FALSE
34	GTEx	Skin Sun Exposed Lower leg	DDX55	0.13	0.05	enet	13	0.10	1.6e-08	-3.4	5.1	2.9e-07	0.07	1.00	0.00	FALSE