[Hub]/) : Traits : Arm predicted mass (right) :

chr17:27,200,734-30,884,028

Best TWAS P=8.52e-32 · Best GWAS P=9.24e-36 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NF1 0.06 0.01 blup 410 0.04 1.1e-05 7.48 6.5 6.1e-11 -0.20 0.95 0.00 FALSE
2 GTEx Adipose Visceral Omentum TEFM 0.12 0.02 lasso 14 0.05 1.0e-03 0.91 -6.0 1.6e-09 0.21 0.08 0.09 FALSE
3 GTEx Artery Aorta ABHD15 0.20 0.03 enet 36 0.06 2.9e-04 -4.96 -7.7 1.9e-14 0.08 0.03 0.55 TRUE
4 GTEx Artery Aorta TEFM 0.13 0.02 enet 34 0.03 5.8e-03 0.93 -6.6 4.9e-11 0.57 0.15 0.78 FALSE
5 GTEx Artery Aorta CRLF3 0.12 0.03 enet 33 0.06 3.8e-04 0.95 -7.4 1.4e-13 0.53 0.25 0.70 TRUE
6 GTEx Artery Tibial RP11-848P1.7 0.54 0.00 lasso 10 0.02 7.3e-03 -7.10 -11.7 8.5e-32 0.47 0.02 0.06 TRUE
7 GTEx Brain Cerebellar Hemisphere CRLF3 0.38 0.35 enet 26 0.35 6.0e-10 2.31 -5.7 1.4e-08 0.32 0.97 0.01 FALSE
8 GTEx Brain Cerebellum CRLF3 0.52 0.12 lasso 27 0.20 1.3e-06 -10.79 -9.4 3.5e-21 0.56 0.09 0.74 FALSE
9 GTEx Cells EBV-transformed lymphocytes EVI2A 0.13 0.03 lasso 4 0.01 1.5e-01 7.48 -8.1 8.4e-16 0.17 0.16 0.04 FALSE
10 GTEx Cells Transformed fibroblasts OMG 0.06 0.02 lasso 2 0.01 2.5e-02 7.50 7.5 7.2e-14 -0.22 0.14 0.07 FALSE
11 GTEx Esophagus Muscularis BLMH 0.15 0.02 lasso 8 0.01 1.0e-01 -3.39 5.7 1.0e-08 -0.13 0.04 0.46 TRUE
12 GTEx Esophagus Muscularis CRLF3 0.17 0.12 lasso 6 0.18 5.1e-11 2.26 -7.3 3.9e-13 0.46 0.94 0.05 FALSE
13 GTEx Muscle Skeletal TP53I13 0.08 0.02 lasso 4 0.02 2.2e-03 -4.96 5.8 7.5e-09 -0.08 0.08 0.30 TRUE
14 GTEx Nerve Tibial CRLF3 0.38 0.16 lasso 14 0.19 3.0e-13 2.35 -6.0 2.4e-09 0.38 1.00 0.00 FALSE
15 GTEx Ovary CRLF3 0.21 0.14 lasso 4 0.11 1.0e-03 2.26 -6.0 1.4e-09 0.40 0.06 0.58 FALSE
16 GTEx Pituitary SUZ12P 0.29 0.23 lasso 9 0.32 6.0e-09 2.31 -5.9 3.7e-09 0.40 0.86 0.07 TRUE
17 GTEx Spleen EVI2A 0.22 0.12 lasso 4 0.07 8.3e-03 7.75 -7.7 2.0e-14 0.17 0.11 0.05 FALSE
18 GTEx Spleen OMG 0.41 0.10 enet 26 0.08 4.5e-03 7.50 7.3 3.2e-13 -0.23 0.64 0.03 FALSE
19 GTEx Testis CRLF3 0.26 0.19 enet 23 0.17 3.8e-08 2.39 -5.4 8.0e-08 0.38 0.99 0.00 FALSE
20 GTEx Thyroid COPRS 0.17 0.00 enet 43 0.01 1.2e-01 1.09 -5.3 9.6e-08 0.13 0.04 0.23 FALSE
21 GTEx Thyroid CRLF3 0.10 0.04 enet 35 0.08 1.1e-06 2.35 -5.8 7.0e-09 0.38 0.91 0.05 FALSE
22 GTEx Whole Blood EVI2A 0.07 0.04 lasso 4 0.04 2.6e-04 7.75 -7.8 4.4e-15 0.14 0.89 0.00 FALSE
23 METSIM Adipose CTD-2349P21.5 0.02 0.00 bslmm 252 0.01 3.0e-03 -9.03 -7.0 2.8e-12 0.33 0.04 0.31 FALSE
24 METSIM Adipose NF1 0.04 0.00 blup 396 0.01 5.5e-03 8.43 7.9 2.9e-15 -0.30 0.80 0.02 FALSE
25 METSIM Adipose TEFM 0.08 0.06 blup 246 0.06 8.8e-10 -12.48 -7.6 3.3e-14 0.57 0.00 1.00 TRUE
26 YFS Blood EVI2A 0.03 0.05 lasso 4 0.04 1.0e-13 7.75 -7.8 7.8e-15 0.10 1.00 0.00 FALSE
27 YFS Blood EVI2B 0.01 0.00 blup 339 0.00 6.4e-02 -0.19 7.0 3.7e-12 -0.26 0.07 0.02 FALSE
28 The Cancer Genome Atlas Bladder Urothelial Carcinoma EVI2A 0.03 0.03 blup 37 0.03 2.3e-03 7.76 -7.7 9.9e-15 0.10 0.02 0.78 FALSE
29 The Cancer Genome Atlas Bladder Urothelial Carcinoma OMG 0.02 0.02 blup 31 0.02 3.2e-03 7.77 -8.1 4.9e-16 0.15 0.02 0.84 FALSE
30 The Cancer Genome Atlas Breast Invasive Carcinoma EVI2A 0.03 0.03 blup 38 0.03 6.9e-07 7.68 -7.9 2.6e-15 0.12 0.02 0.98 FALSE
31 The Cancer Genome Atlas Breast Invasive Carcinoma GOSR1 0.02 0.01 enet 4 0.01 1.7e-02 -7.15 7.2 5.0e-13 -0.27 0.01 0.83 FALSE
32 The Cancer Genome Atlas Breast Invasive Carcinoma OMG 0.03 0.04 lasso 1 0.04 1.1e-08 7.64 -7.6 2.2e-14 0.23 0.03 0.97 FALSE
33 The Cancer Genome Atlas Colon Adenocarcinoma LRRC37B2 0.09 0.00 enet 11 0.03 7.3e-03 3.25 -6.2 6.4e-10 0.47 0.01 0.26 TRUE
34 The Cancer Genome Atlas Esophageal Carcinoma OMG 0.09 0.09 blup 31 0.11 2.0e-04 7.73 -8.1 3.9e-16 0.18 0.02 0.91 FALSE
35 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EVI2A 0.04 0.00 blup 37 0.01 1.1e-02 7.71 -6.2 5.0e-10 0.00 0.01 0.52 FALSE
36 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma OMG 0.02 0.02 blup 31 0.03 6.9e-04 7.70 -8.1 5.9e-16 0.17 0.02 0.89 FALSE
37 The Cancer Genome Atlas Brain Lower Grade Glioma EVI2A 0.03 0.03 blup 38 0.04 3.0e-05 7.72 -8.1 4.7e-16 0.16 0.04 0.96 FALSE
38 The Cancer Genome Atlas Liver Hepatocellular Carcinoma NF1 0.04 0.03 blup 111 0.03 1.3e-02 7.71 7.9 2.2e-15 -0.19 0.08 0.47 FALSE
39 The Cancer Genome Atlas Lung Adenocarcinoma EVI2A 0.04 0.06 blup 38 0.06 3.0e-07 7.65 -8.1 6.5e-16 0.15 0.07 0.93 FALSE
40 The Cancer Genome Atlas Lung Adenocarcinoma OMG 0.05 0.03 lasso 5 0.04 3.6e-05 7.64 -6.7 1.8e-11 0.10 0.02 0.94 FALSE
41 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EVI2A 0.03 0.03 lasso 1 0.02 2.4e-03 7.51 -7.5 5.7e-14 0.10 0.02 0.67 FALSE
42 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma GOSR1 0.15 0.00 blup 56 0.04 1.1e-03 -3.06 6.2 5.9e-10 -0.35 0.04 0.19 FALSE
43 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma OMG 0.05 0.03 blup 32 0.03 5.6e-03 7.50 -7.1 1.0e-12 0.25 0.02 0.63 FALSE
44 The Cancer Genome Atlas Prostate Adenocarcinoma EVI2A 0.08 0.12 lasso 3 0.12 1.3e-12 8.43 -8.2 2.0e-16 0.12 0.01 0.99 FALSE
45 The Cancer Genome Atlas Stomach Adenocarcinoma EVI2A 0.05 0.03 enet 7 0.04 4.8e-04 4.16 -6.7 2.0e-11 0.13 0.04 0.60 FALSE
46 The Cancer Genome Atlas Stomach Adenocarcinoma SUZ12P 0.05 0.05 blup 29 0.04 5.1e-04 2.83 -5.3 1.0e-07 0.32 0.16 0.16 TRUE
47 The Cancer Genome Atlas Thyroid Carcinoma OMG 0.02 0.01 blup 32 0.02 4.8e-03 7.50 -8.1 5.1e-16 0.18 0.02 0.85 FALSE