[Hub]/) : Traits : Arm predicted mass (right) : ←

chr22:38,787,166-43,226,599

Best TWAS P=1.99e-10 · Best GWAS P=1.39e-15 conditioned to 5.24e-08

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	WBP2NL	0.28	0.25	enet	16	0.35	1.3e-43	5.0	5.4	8.0e-08	-0.35	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	CYP2D6	0.26	0.10	enet	34	0.20	1.2e-16	-4.2	-6.3	2.7e-10	0.45	1.00	0.00	TRUE
3	GTEx	Adrenal Gland	CYP2D6	0.37	0.14	lasso	12	0.16	2.3e-06	-4.2	-5.3	1.2e-07	0.41	0.97	0.00	FALSE
4	GTEx	Artery Aorta	CYP2D6	0.24	0.14	lasso	5	0.24	1.6e-13	-4.3	-5.2	2.5e-07	0.40	1.00	0.00	FALSE
5	GTEx	Artery Aorta	APOBEC3G	0.40	0.40	lasso	3	0.39	6.3e-23	5.0	5.4	6.5e-08	0.07	0.04	0.96	FALSE
6	GTEx	Artery Tibial	CYP2D6	0.29	0.23	lasso	6	0.28	1.5e-22	4.5	-5.1	2.7e-07	0.37	1.00	0.00	FALSE
7	GTEx	Brain Cerebellar Hemisphere	CYP2D6	0.49	0.38	enet	16	0.49	1.6e-14	-4.2	-5.2	2.6e-07	0.40	1.00	0.00	FALSE
8	GTEx	Brain Cortex	CYP2D6	0.51	0.33	lasso	6	0.47	1.5e-14	-4.3	-5.2	2.1e-07	0.41	1.00	0.00	FALSE
9	GTEx	Brain Frontal Cortex BA9	CYP2D6	0.51	0.20	lasso	5	0.34	9.0e-10	4.5	-5.3	1.1e-07	0.39	0.92	0.05	FALSE
10	GTEx	Brain Frontal Cortex BA9	SLC25A17	0.11	-0.01	lasso	5	0.00	3.5e-01	-4.1	-5.4	8.4e-08	0.22	0.08	0.18	FALSE
11	GTEx	Breast Mammary Tissue (Male)	CYP2D6	0.34	-0.01	lasso	6	0.00	3.2e-01	4.9	-5.6	2.5e-08	0.36	0.11	0.10	FALSE
12	GTEx	Breast Mammary Tissue (Female)	POLR3H	0.09	-0.01	lasso	6	-0.01	6.4e-01	-5.6	5.6	1.7e-08	-0.46	0.04	0.06	FALSE
13	GTEx	Breast Mammary Tissue (Female)	DESI1	0.14	0.07	lasso	4	0.11	4.2e-04	-5.6	5.4	6.9e-08	-0.45	0.08	0.12	FALSE
14	GTEx	Cells Transformed fibroblasts	APOBEC3G	0.24	0.20	enet	11	0.24	9.4e-18	4.8	5.3	1.3e-07	0.05	0.07	0.92	FALSE
15	GTEx	Colon Sigmoid	DESI1	0.21	0.08	enet	6	0.11	1.2e-04	-5.6	5.4	6.4e-08	-0.47	0.40	0.05	FALSE
16	GTEx	Esophagus Muscularis	CYP2D6	0.33	0.18	lasso	5	0.29	5.6e-18	-3.5	-5.2	2.3e-07	0.44	1.00	0.00	FALSE
17	GTEx	Lung	RP5-821D11.7	0.08	0.02	enet	21	0.04	6.6e-04	3.8	6.3	3.3e-10	-0.40	0.53	0.04	FALSE
18	GTEx	Nerve Tibial	CYP2D6	0.32	0.21	lasso	6	0.24	2.8e-17	4.6	-5.4	5.9e-08	0.39	1.00	0.00	FALSE
19	GTEx	Nerve Tibial	SYNGR1	0.26	0.18	enet	27	0.21	3.6e-15	-4.4	-5.2	2.4e-07	0.05	0.18	0.81	FALSE
20	GTEx	Nerve Tibial	COX5BP7	0.44	0.25	enet	33	0.25	1.7e-17	3.8	-5.1	3.1e-07	0.01	0.70	0.24	FALSE
21	GTEx	Pituitary	OLA1P1	0.31	0.10	enet	9	0.08	5.0e-03	4.5	5.2	1.5e-07	-0.39	0.23	0.08	FALSE
22	GTEx	Pituitary	APOBEC3G	0.34	0.04	enet	11	0.11	1.2e-03	4.8	5.8	6.8e-09	0.03	0.02	0.83	TRUE
23	GTEx	Skin Sun Exposed Lower leg	APOBEC3G	0.10	0.09	lasso	3	0.06	7.5e-06	5.0	5.3	1.1e-07	0.07	0.04	0.95	FALSE
24	GTEx	Spleen	CCDC134	0.23	0.00	enet	14	0.09	2.7e-03	-5.6	5.8	6.7e-09	-0.40	0.07	0.07	FALSE
25	GTEx	Testis	SREBF2	0.25	0.03	lasso	12	0.04	4.6e-03	4.5	5.5	2.9e-08	-0.41	0.62	0.04	FALSE
26	GTEx	Uterus	NAGA	0.19	0.07	enet	8	0.06	2.6e-02	-4.1	5.2	1.8e-07	-0.34	0.08	0.06	FALSE
27	GTEx	Vagina	APOBEC3G	0.23	0.07	lasso	5	0.06	1.8e-02	4.9	5.4	6.0e-08	0.05	0.06	0.49	FALSE
28	NTR	Blood	SYNGR1	0.03	0.03	enet	6	0.03	1.0e-10	5.0	5.3	9.7e-08	0.08	0.04	0.96	TRUE
29	The Cancer Genome Atlas	Breast Invasive Carcinoma	TNRC6B	0.02	0.01	blup	92	0.01	2.7e-03	-5.0	-5.6	2.4e-08	0.12	0.02	0.78	FALSE
30	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CYP2D6	0.14	0.09	enet	2	0.14	1.3e-07	4.5	-5.2	1.7e-07	0.38	0.00	0.91	FALSE
31	The Cancer Genome Atlas	Colon Adenocarcinoma	CYP2D6	0.12	0.11	enet	2	0.13	7.7e-08	4.5	-5.2	1.9e-07	0.38	0.00	0.95	FALSE
32	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	WBP2NL	0.06	0.04	blup	140	0.03	9.6e-05	-5.6	6.3	3.1e-10	-0.53	0.58	0.24	FALSE
33	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADSL	0.04	0.03	enet	6	0.03	1.6e-04	-6.5	-5.6	2.6e-08	0.02	0.00	0.94	FALSE
34	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CYP2D6	0.14	0.15	enet	2	0.17	1.4e-18	4.5	-5.1	2.8e-07	0.36	0.00	0.97	FALSE
35	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	WBP2NL	0.10	0.04	blup	140	0.05	1.8e-06	-4.0	6.0	1.5e-09	-0.40	0.98	0.00	FALSE
36	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CYP2D6	0.15	0.07	blup	2	0.15	4.0e-09	4.5	-5.2	1.7e-07	0.39	0.00	0.96	FALSE
37	The Cancer Genome Atlas	Brain Lower Grade Glioma	CYP2D6	0.19	0.17	enet	2	0.26	3.6e-29	-4.3	-5.2	1.8e-07	0.40	0.00	0.93	FALSE
38	The Cancer Genome Atlas	Lung Adenocarcinoma	ADSL	0.03	0.00	blup	33	0.01	8.9e-03	-6.2	-5.7	1.4e-08	0.06	0.01	0.60	FALSE
39	The Cancer Genome Atlas	Lung Adenocarcinoma	CYP2D6	0.12	0.13	enet	2	0.15	7.4e-17	4.5	-5.2	2.1e-07	0.37	0.00	0.97	FALSE
40	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CYP2D6	0.20	0.23	enet	2	0.25	3.4e-28	4.5	-5.2	2.5e-07	0.37	0.00	0.97	FALSE
41	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ADSL	0.06	0.02	lasso	2	0.03	6.6e-03	-6.3	-6.3	2.7e-10	0.05	0.00	0.80	FALSE
42	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ADSL	0.09	0.03	lasso	3	0.01	7.7e-02	-6.5	-6.4	2.0e-10	0.11	0.00	0.76	TRUE
43	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CSDC2	0.25	0.01	enet	11	0.06	2.3e-03	-3.1	-5.5	3.7e-08	0.21	0.00	0.00	TRUE
44	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CYP2D6	0.19	0.13	enet	2	0.14	1.6e-06	4.5	-5.1	2.7e-07	0.36	0.00	0.82	FALSE
45	The Cancer Genome Atlas	Prostate Adenocarcinoma	WBP2NL	0.04	0.03	lasso	8	0.03	5.6e-04	5.0	5.4	6.5e-08	-0.34	0.56	0.03	FALSE
46	The Cancer Genome Atlas	Soft Tissue Sarcoma	CYP2D6	0.11	0.09	blup	2	0.10	1.4e-06	4.5	-5.2	2.3e-07	0.37	0.00	0.94	FALSE
47	The Cancer Genome Atlas	Skin Cutaneous Melanoma	CYP2D6	0.11	0.00	blup	2	0.00	2.7e-01	-4.3	-5.2	2.1e-07	0.40	0.00	0.02	FALSE
48	The Cancer Genome Atlas	Stomach Adenocarcinoma	CYP2D6	0.12	0.10	blup	2	0.10	6.5e-08	4.5	-5.2	2.6e-07	0.36	0.00	0.97	FALSE
49	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	CYP2D6	0.19	0.06	blup	2	0.10	9.6e-04	4.5	-5.2	1.7e-07	0.39	0.00	0.16	FALSE