TWAS hub - OLA1P1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Liver	0.367	0.099	3.0e-06	0.395	NA	0.293	NA	0.346	4.2e-12	NA	7.6e-09	NA	1.7e-10
2	GTEx	Pituitary	0.306	0.114	9.8e-04	0.103	NA	0.079	NA	0.034	1.5e-03	NA	5.0e-03	NA	4.8e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Verbal and Numeric Reasoning (VNR)	11.0	26.4	28.8	-5.4	-4.9
Bipolar Disorder or Schizophrenia	9.0	21.8	28.6	5.3	3.9
Intelligence (Savage-Jansen 2018)	8.9	27.2	27.4	-5.2	-5.2
Schizophrenia (2018)	7.8	16.2	23.3	4.8	3.0
Chronotype (morning person)	7.6	17.5	21.7	3.7	4.7
Schizophrenia (2014)	7.2	15.9	21.9	4.7	3.2
Hand grip strength (left)	7.2	19.1	21.7	4.1	4.7
Ever smoked	7.2	12.6	16.7	-2.9	-4.1
Birth weight of first child	6.1	11.1	13.9	2.9	3.7
Osteoporosis (self-reported)	5.8	7.2	9.3	2.3	3.0
Fluid intelligence score	5.7	11.9	13.2	-3.6	-3.3
Diastolic blood pressure, automated reading	5.5	17.0	17.2	4.1	4.2
Past tobacco smoking	5.3	9.7	13.3	2.5	3.6
Had other major operations	5.3	6.5	6.5	-2.5	-2.5
Qualifications: College or University degree	5.2	16.4	16.7	-4.0	-4.1
Myopia	5.1	7.3	10.2	-2.1	-3.2
Hair/balding pattern: Pattern 2	5.0	6.3	7.6	2.8	2.3
Body Mass Index (BMI) (2010)	4.9	6.7	8.3	2.3	2.9
Hand grip strength (right)	4.7	12.8	12.9	3.6	3.6
Mean time to correctly identify matches	4.7	9.0	10.4	-2.8	-3.2
Arm predicted mass (right)	4.7	24.0	27.5	4.5	5.2
Friendships satisfaction	4.7	5.8	7.1	2.7	2.1
Illnesses of father: None of the above (group 1)	4.7	5.8	6.3	-2.5	-2.3
Average weekly fortified wine intake	4.6	5.4	5.8	-2.2	-2.4
Chronic bronchitis/emphysema (father)	4.6	5.4	5.7	2.2	2.4
Happiness	4.6	5.6	7.0	2.6	2.1
Qualifications: A levels/AS levels or equivalent	4.6	10.1	11.5	-3.0	-3.4
Supplements: Glucosamine	4.5	5.8	6.1	-2.5	-2.4
Frequency of tiredness / lethargy in last 2 weeks	4.5	7.3	8.9	2.4	3.0
Comparative body size at age 10	4.5	12.4	13.1	3.6	3.4
Breast cancer (self-reported)	4.5	5.3	6.5	-2.6	-2.0
Smoking Status	4.2	9.9	14.9	-2.2	-3.9
Trunk fat-free mass	4.2	24.1	25.8	4.7	5.1
Trunk predicted mass	4.2	24.2	25.9	4.7	5.1
Arm fat-free mass (right)	4.1	20.9	25.1	4.1	5.0
Arm fat-free mass (left)	4.1	20.6	23.0	4.3	4.8
Medication: Paracetamol	4.0	6.2	6.7	2.4	2.6
Bipolar Disorder (2018)	3.9	6.2	6.4	2.5	2.5
High blood pressure (mother)	3.9	5.5	6.2	2.5	2.2
Mood swings	3.9	7.1	7.3	2.6	2.7
Arm predicted mass (left)	3.9	20.0	22.1	4.2	4.7
Medication: Paracetamol	3.8	6.3	6.4	2.5	2.5
Whole body fat-free mass	3.7	21.0	24.3	4.2	4.9
Depression (Nagel 2018)	3.6	5.4	7.2	2.7	1.9
Number of incorrect matches in round	3.6	6.0	7.3	2.2	2.7
Medication for pain relief, constipation, heartburn	3.6	6.1	7.1	-2.2	-2.7
Age started oral contraceptive pill	3.6	4.6	5.0	-2.2	-2.0
Average weekly spirits intake	3.5	4.4	4.8	-2.2	-2.0
Systolic blood pressure, automated reading	3.5	10.1	11.8	3.4	2.9
Stomach or abdominal pain in last month	3.5	4.3	5.9	2.4	1.7
Smoking status: Previous	3.5	5.2	6.5	-2.0	-2.5
Whole body water mass	3.5	20.1	23.2	4.1	4.8
Basal metabolic rate	3.5	19.6	22.9	4.0	4.8
Bipolar Disorder (2011)	3.3	3.2	3.4	1.7	1.9
Hearing difficulty/problems: Yes	3.2	4.9	5.3	-2.1	-2.3
Eye problems/disorders: Diabetes related eye disease	3.2	3.5	5.0	1.4	2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	3.1	4.1	5.4	2.3	1.7
Heart disease (mother)	3.1	3.8	6.0	1.3	2.4
Lung FVC	3.0	15.1	17.4	-3.6	-4.2
Headache pain in last month	3.0	5.2	6.5	2.0	2.6
Hair/balding pattern: Pattern 4	2.9	7.0	8.1	-2.8	-2.4
Birth weight	2.9	6.2	7.6	2.2	2.8
Overall health rating	2.9	6.3	6.9	2.6	2.4
Age at First Birth	2.8	4.0	5.2	-2.3	-1.7
Noisy workplace	2.8	3.4	3.9	1.7	2.0
Irritability	2.8	4.7	5.7	2.0	2.4
Unable to work because of sickness or disability	2.8	3.6	5.2	2.3	1.4
Illnesses of mother	2.7	3.3	4.8	-1.3	-2.2
Mother’s age at death	2.7	3.4	5.1	-2.3	-1.3
Impedance of arm (right)	2.6	12.2	13.0	-3.4	-3.6
Worrier / anxious feelings	2.6	4.8	5.0	2.2	2.2
Pulse wave Arterial Stiffness index	2.6	3.0	4.3	1.3	2.1
Impedance of arm (left)	2.6	12.1	13.1	-3.6	-3.3
Leg fat-free mass (right)	2.6	13.9	17.2	3.2	4.2
Leg predicted mass (right)	2.6	14.0	17.5	3.2	4.2
Heel T-Score	2.5	20.2	24.5	-4.0	-5.0
Diabetes (father)	2.5	3.2	3.3	1.7	1.8
Body mass index (BMI)	2.5	10.5	12.8	2.8	3.6
Mouth/teeth dental problems: Bleeding gums	2.5	3.2	3.9	1.6	2.0
High blood pressure (siblings)	2.5	3.6	3.7	1.9	1.9
Family relationship satisfaction	2.5	3.0	3.5	1.9	1.6
Eye problems/disorders: Cataract	2.5	2.9	3.6	-1.9	-1.5
Number of self-reported non-cancer illnesses	2.5	4.3	5.6	1.7	2.4
BMI	2.4	14.0	17.7	3.2	4.2
Weight	2.4	11.9	15.0	3.0	3.9
Medication: Cholesterol lowering	2.4	3.7	4.6	1.7	2.1
Vascular/heart problems diagnosed by doctor	2.4	6.5	6.6	-2.6	-2.6
Qualifications: CSEs or equivalent	2.3	3.0	3.3	1.7	1.8
Breastfed as a baby	2.3	2.8	3.3	-1.8	-1.6
Pulse wave peak to peak time	2.3	2.7	3.9	-1.3	-2.0
Leg fat-free mass (left)	2.2	11.8	15.0	2.9	3.9
Heel bone mineral density (BMD) T-score, automated (left)	2.2	5.0	5.3	-2.2	-2.3
Leg predicted mass (left)	2.2	11.8	15.1	2.9	3.9
Alcohol intake frequency.	2.2	5.1	7.4	1.6	2.7
Chest pain or discomfort	2.2	3.2	3.4	1.8	1.7
Qualifications: NVQ or HND or HNC or equivalent	2.2	2.6	2.7	1.6	1.6
Illness, injury, bereavement, stress in last 2 years	2.2	2.7	2.8	-1.7	-1.6
Irritable Bowel Disease (IBD)	2.1	4.9	5.1	2.2	2.3
Angina (self-reported)	2.1	2.8	2.9	1.6	1.7
Long-standing illness, disability or infirmity	2.1	3.2	3.4	1.7	1.9
Qualifications: nursing, teaching	2.1	3.3	4.5	-2.1	-1.4
Guilty feelings	2.1	3.2	3.6	1.9	1.7
Crohns Disease (2012)	2.0	3.3	4.4	1.5	2.1
Neuroticism score	2.0	4.1	4.4	2.1	2.0
Health satisfaction	2.0	2.6	3.8	1.9	1.2
Arm fat mass (left)	2.0	8.1	10.6	2.4	3.3
Systolic Blood Pressure	1.9	9.3	11.3	3.4	2.7
Respiratory disease	1.9	4.2	6.4	1.4	2.5
High blood pressure	1.9	5.4	5.7	2.4	2.2
Impedance of whole body	1.9	9.9	10.3	-3.1	-3.2
Neuroticism (Nagel 2018)	1.8	4.3	4.5	2.0	2.1
Worry (Nagel 2018)	1.8	3.8	3.9	2.0	1.9
Mean Putamen Volume	1.8	2.1	2.1	-1.4	-1.5
Lung FEV1/FVC ratio	1.8	9.0	9.1	3.0	3.0
Number of treatments/medications taken	1.8	3.3	4.7	1.4	2.2
Angina	1.8	2.4	2.5	1.5	1.6
Had menopause	1.8	2.3	3.4	-1.9	-1.1
Arm fat mass (right)	1.8	7.4	9.6	2.3	3.1
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	2.3	1.5	1.5
Allergy	1.7	3.9	6.1	-1.3	-2.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	2.8	1.7	1.1
Leg fat mass (left)	1.7	6.6	8.4	2.2	2.9
Townsend deprivation index at recruitment	1.6	2.3	2.9	-1.3	-1.7
Leg fat mass (right)	1.6	6.0	8.1	2.0	2.8
Commuting to job workplace: Car/motor vehicle	1.6	1.9	2.2	1.2	1.5
Hypertension (Self-reported)	1.6	4.5	4.8	2.2	2.1
Alzheimer’s Disease (in mother)	1.5	1.8	3.1	-0.7	-1.8
Frequency of depressed mood in last 2 weeks	1.5	2.1	2.6	1.6	1.3
Depressed Affect (Nagel 2018)	1.4	3.0	4.0	1.4	2.0
Blood White Count	1.4	10.5	14.1	3.8	2.6
Neuroticism	1.4	3.3	3.4	1.9	1.8
Medication: Ramipril	1.4	1.9	2.3	1.2	1.5
Alcohol intake versus 10 years previously	1.4	2.1	2.5	1.3	1.6
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	2.4	-1.4	-1.6
Age at first live birth	1.4	2.5	2.5	-1.6	-1.5
Age at last live birth	1.4	2.0	2.1	-1.4	-1.4
Tinnitus: Yes, now most or all of the time	1.4	1.6	1.6	-1.3	-1.3
Heart attack/myocardial infarction (self-reported)	1.4	1.8	2.2	1.2	1.5
Ulcerative Colitis (UC)	1.3	2.4	3.1	1.8	1.3
Reaction Time	1.3	2.5	3.7	-1.1	-1.9
Rheumatoid Arthritis	1.3	1.8	2.7	-1.0	-1.6
Ever used hormone-replacement therapy (HRT)	1.3	1.6	2.5	0.9	1.6
Severe depression (siblings)	1.3	1.4	2.1	1.4	0.9
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	2.1	1.5	1.0
Medication for cholesterol, blood pressure or diabetes	1.3	2.2	3.1	-1.1	-1.8
Commuting to job workplace: Public transport	1.3	1.6	2.2	-1.0	-1.5
Supplements: Calcium	1.3	1.4	2.3	0.7	1.5
Crohns Disease (2017)	1.2	2.7	3.5	1.4	1.9
Current tobacco smoking	1.2	2.0	3.5	-0.7	-1.9
Hip circumference	1.2	5.4	7.4	1.8	2.7
Whole body fat mass	1.2	5.0	6.8	1.8	2.6
Number of operations (self-reported)	1.2	1.8	2.0	-1.4	-1.3
Fed-up feelings	1.1	2.1	2.7	1.2	1.6
Trunk fat mass	1.1	4.6	6.6	1.6	2.6
Pulse wave reflection index	1.1	1.3	2.3	0.5	1.5
Blood clot in the leg (DVT)	1.1	1.4	1.5	1.1	1.2
Smoking status: Current	1.1	1.8	3.1	-0.7	-1.8
Financial situation satisfaction	1.1	1.4	1.7	1.3	1.0
Supplements: Fish oil (including cod liver oil)	1.1	1.4	1.8	1.3	1.0
Heart disease (siblings)	1.1	1.3	1.5	1.1	1.2
Cardiovascular Disease	1.0	3.3	3.4	1.8	1.8
Impedance of leg (right)	1.0	4.7	6.0	-1.9	-2.4
Maternal smoking around birth	1.0	1.5	2.0	1.4	0.9
Hearing difficulty/problems with background noise	1.0	1.6	1.9	-1.1	-1.4
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	1.8	0.9	1.4
Migraine (self-reported)	1.0	1.2	2.4	0.3	1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	1.1	-1.0	-1.1
Alcohol drinker status: Never	1.0	1.2	2.0	0.6	1.4
Ovarian Cancer	0.9	1.2	2.1	-1.5	-0.5
Coronary Artery Disease (CAD)	0.9	1.1	1.7	-1.3	-0.7
Waist circumference	0.9	3.3	4.3	1.5	2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	2.4	-1.3	-1.6
Heart attack	0.9	1.2	1.4	1.0	1.2
Medication: Simvastatin	0.9	1.4	2.0	0.9	1.4
Depression (self-reported)	0.9	1.1	1.2	1.1	1.0
Medication: Lansoprazole	0.9	1.1	1.2	1.0	1.1
Lung cancer (father)	0.9	1.1	1.2	-1.0	-1.1
Exposure to tobacco smoke outside home	0.9	1.1	1.7	-0.7	-1.3
Number of children fathered	0.9	1.0	1.7	1.3	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	1.1	1.0	1.0
Osteoarthritis (self-reported)	0.9	1.1	1.4	-1.2	-0.9
Risk taking	0.9	1.4	1.6	-1.1	-1.2
Breast Cancer	0.8	1.9	2.1	1.5	1.3
Primary Biliary Cirrhosis	0.8	1.2	1.7	1.3	0.8
Hayfever, allergic rhinitis or eczema	0.8	1.7	3.1	0.5	1.8
Illnesses of siblings	0.8	1.1	1.4	-0.9	-1.2
Peak expiratory flow (PEF)	0.8	1.7	2.4	1.1	1.5
Ever had bowel cancer screening	0.8	0.9	1.2	1.1	0.8
Medication: Gliclazide	0.8	0.9	1.3	1.2	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.6	2.2	-1.5	-1.0
Leg fat percentage (left)	0.8	3.0	4.1	1.4	2.0
Schizophrenia vs Biploar Disorder	0.7	1.0	1.7	1.3	0.4
Type 2 Diabetes (T2D) (2018)	0.7	1.3	1.8	0.9	1.3
Medication: Atenolol	0.7	0.9	1.0	1.0	0.9
Alcohol usually taken with meals	0.7	1.1	1.7	0.7	1.3
Arm fat percentage (right)	0.7	2.7	3.8	1.3	1.9
Father’s age at death	0.7	0.9	1.0	-0.9	-1.0
Exposure to tobacco smoke at home	0.7	0.8	1.0	1.0	0.8
Number of full brothers	0.7	0.8	0.9	-0.9	-0.9
Back pain experienced in last month	0.7	1.1	1.4	0.9	1.2
Allergy or Eczema	0.6	1.5	2.7	0.5	1.6
Forced vital capacity (FVC)	0.6	2.4	2.4	-1.5	-1.5
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	0.9	0.8	1.0
Tense / ‘highly strung’	0.6	1.0	1.8	0.4	1.4
Forced vital capacity (FVC), Best measure	0.6	2.2	2.5	-1.4	-1.6
Body fat percentage	0.6	2.2	3.3	1.0	1.8
Leg fat percentage (right)	0.6	2.2	3.2	1.1	1.8
Medication: Ibuprofen	0.6	0.7	0.9	0.7	1.0
Number of full sisters	0.6	0.7	1.1	1.0	0.5
Suffer from ‘nerves’	0.6	0.9	1.0	1.0	0.9
Knee pain experienced in last month	0.6	0.9	1.0	0.9	1.0
Illnesses of father: Heart disease	0.6	0.8	0.9	0.9	0.9
Arm fat percentage (left)	0.6	2.6	3.9	1.1	2.0
Asthma (self-reported)	0.6	1.1	1.8	0.7	1.3
Average weekly champagne plus white wine intake	0.6	0.8	0.8	0.9	0.9
Miserableness	0.6	1.1	1.2	1.1	1.0
Ever had prostate specific antigen (PSA) test	0.6	0.7	0.8	0.8	0.9
Alzheimer’s Disease (in father)	0.5	0.5	0.5	0.7	-0.7
LDL Cholesterol	0.5	0.8	1.0	1.0	0.8
Blood Eosinophil Count	0.5	3.9	6.0	2.5	1.3
Medication for hormone replacement therapy	0.5	0.6	0.9	0.6	0.9
Taking other prescription medications	0.5	0.7	1.2	0.5	1.1
Age when periods started (menarche)	0.5	1.3	2.5	-0.3	-1.6
Serious illness, injury or assault to yourself	0.5	0.6	0.9	0.4	1.0
Impedance of leg (left)	0.5	2.4	3.3	-1.2	-1.8
Gout (self-reported)	0.5	0.7	0.9	0.7	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	0.8	0.9	0.7
Medication: Blood pressure	0.5	0.9	1.1	0.8	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	1.4	0.8	1.2
Average weekly red wine intake	0.5	0.8	1.0	-1.0	-0.7
Commuting to job workplace: Walk	0.5	0.5	0.6	-0.6	-0.8
Pain experienced in last month	0.5	0.9	1.0	-0.9	-1.0
Prostate Cancer	0.4	0.6	0.7	-0.7	-0.8
HbA1C	0.4	0.4	0.8	0.0	0.9
Neuroticism (2016)	0.4	0.6	0.6	0.8	0.7
Type 2 Diabetes (T2D) (2012)	0.4	0.4	0.5	-0.5	-0.7
Waist Hip Ratio (WHR)	0.4	1.6	2.1	-1.1	-1.4
Trunk fat percentage	0.4	1.8	2.9	0.8	1.7
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	0.8	0.9	0.4
Asthma	0.4	0.8	1.2	0.6	1.1
Prospective memory result	0.4	0.5	0.7	0.8	0.7
Ever highly irritable/argumentative for 2 days	0.4	0.4	0.5	0.7	0.6
Loud music exposure frequency	0.4	0.4	0.7	-0.1	-0.9
Eye problems/disorders: None of the above	0.4	0.5	0.9	1.0	0.2
Mouth/teeth dental problems: Loose teeth	0.4	0.4	0.6	0.8	-0.5
Supplements: Vitamin C	0.4	0.5	0.6	-0.5	-0.8
Loneliness, isolation	0.4	0.5	1.0	0.1	1.0
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.2	-0.1	-1.1
Cholesterol lowering medication	0.4	0.6	0.9	1.0	0.5
Basal cell carcinoma (self-reported)	0.4	0.5	0.9	0.3	0.9
Pack years of smoking	0.4	0.6	1.3	0.0	-1.1
Alzheimer’s Disease (including proxy)	0.3	0.5	0.8	0.5	-0.9
Major Depression (MDD)	0.3	0.3	0.6	0.8	0.3
Ulcerative Colitis	0.3	0.5	0.5	0.7	0.7
Hypothyroidism (self reported)	0.3	0.6	1.1	-0.3	-1.1
Qualifications: None of the above	0.3	0.6	0.7	0.8	0.8
Financial difficulties in last 2 years	0.3	0.4	0.4	-0.6	-0.6
Mouth/teeth dental problems	0.3	0.5	0.7	-0.8	-0.6
Shortness of breath walking on level ground	0.3	0.3	0.5	0.7	0.4
Emphysema/chronic bronchitis	0.3	0.3	0.6	0.7	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	0.6	0.8	0.0
Leg pain on walking	0.3	0.4	0.7	0.9	0.3
Illnesses of siblings: Diabetes	0.3	0.4	0.6	0.4	0.8
Hearing aid user	0.3	0.4	0.7	0.1	0.8
High cholesterol (Self-reported)	0.3	0.5	0.6	0.7	0.6
Medication: Bendroflumethiazide	0.3	0.4	0.6	-0.8	-0.5
Fractured/broken bones in last 5 years	0.3	0.4	0.7	0.1	0.8
Commuting to job workplace: Cycle	0.3	0.3	0.5	0.5	0.7
Height	0.2	3.3	3.8	1.7	1.9
Ever had hysterectomy (womb removed)	0.2	0.2	0.2	0.5	0.4
Medication: Co-codamol	0.2	0.3	0.4	-0.4	-0.6
Diabetes (mother)	0.2	0.3	0.6	0.7	-0.1
Pack years adult smoking proportion	0.2	0.3	0.4	0.5	-0.7
Medication: Levothyroxine sodium	0.2	0.4	0.8	-0.2	-0.9
Nervous feelings	0.2	0.4	0.8	-0.0	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	0.0	-0.6
Standing height	0.2	1.8	2.2	1.1	1.5
Glaucoma (self-reported)	0.2	0.3	0.4	-0.3	-0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.6	-0.4	-0.8
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.6	-0.0	0.8
Worry too long after embarrassment	0.2	0.3	0.6	0.7	-0.3
Medication: Seretide 50 evohaler	0.2	0.2	0.3	0.6	0.4
Had major operations	0.2	0.2	0.2	-0.4	-0.5
Medication: Blood pressure	0.2	0.5	0.5	0.7	0.7
Illnesses of father: High blood pressure	0.2	0.3	0.4	0.4	0.7
Blood Platelet Count	0.1	1.4	2.6	0.5	-1.6
Blood Red Count	0.1	0.5	0.7	0.8	0.6
Hair Pigment	0.1	3.0	4.6	-1.2	-2.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.2	0.2	-0.5
Vitamin and mineral supplements	0.1	0.1	0.3	0.5	0.1
Relative age voice broke	0.1	0.2	0.2	0.5	0.2
Multivitamins +/- minerals	0.1	0.1	0.1	-0.3	0.3
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.2	0.5	0.3
Sitting height	0.1	0.8	1.1	0.7	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.1	0.2	-0.4
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.2	0.4	0.2
Diabetes (self-reported)	0.1	0.2	0.3	0.3	0.5
Time employed in main current job	0.1	0.1	0.2	0.5	0.2
Falls in the last year	0.1	0.1	0.2	0.3	0.4
Hair/balding pattern: Pattern 3	0.1	0.1	0.3	0.1	-0.5
Pulse rate	0.1	0.2	0.2	0.5	0.3
Mouth/teeth dental problems: Dentures	0.1	0.1	0.3	0.5	0.1
Length of working week for main job	0.1	0.1	0.2	0.2	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.2	0.4	-0.0
Wheeze or whistling in the chest in last year	0.1	0.1	0.2	0.4	0.2
Medication: Omeprazole	0.1	0.1	0.2	0.5	0.0
Pulse rate, automated reading	0.1	0.3	0.5	0.7	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.3	-0.6	0.0
Diabetes diagnosed by doctor	0.1	0.1	0.2	0.2	0.5
Medication: Aspirin	0.1	0.2	0.2	0.4	0.4
Wears glasses or contact lenses	0.1	0.2	0.3	-0.6	0.1
Ever taken oral contraceptive pill	0.1	0.1	0.2	0.1	-0.4
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.3	0.5	0.2
Medication: Lisinopril	0.1	0.2	0.2	0.4	0.4
Average weekly beer plus cider intake	0.1	0.2	0.2	0.3	-0.5
Alcohol drinker status: Previous	0.1	0.1	0.2	0.5	0.2
Fasting Glucose	0.0	0.0	0.1	-0.3	0.0
HDL Cholesterol	0.0	0.0	0.0	-0.1	-0.1
Lupus	0.0	0.1	0.1	0.3	0.2
Triglycerides	0.0	0.0	0.1	0.2	-0.0
Tanning	0.0	0.3	0.6	-0.1	-0.8
Sensitivity / hurt feelings	0.0	0.0	0.1	0.2	-0.1
Relative age of first facial hair	0.0	0.0	0.1	-0.3	-0.0
Supplements: Zinc	0.0	0.0	0.0	0.1	0.2
Medication: Metformin	0.0	0.0	0.0	-0.2	-0.0
Pain all over the body in last month	0.0	0.0	0.0	0.2	-0.0
Number of live births	0.0	0.0	0.0	-0.2	-0.1
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.2	-0.4	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.1	-0.3	-0.3
Medication: Amlodipine	0.0	0.0	0.0	0.0	0.2
Medication: Ventolin 100micrograms inhaler	0.0	0.0	0.0	-0.1	0.0
Neck or shoulder pain in last month	0.0	0.0	0.1	-0.3	-0.0
Medication: Allopurinol	0.0	0.1	0.1	-0.1	0.3
Comparative height size at age 10	0.0	0.1	0.2	-0.4	-0.3
Medication: Aspirin	0.0	0.0	0.0	-0.1	0.1
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.1	0.3	0.0
Medication for cholesterol	0.0	0.0	0.0	0.1	0.1
Mineral and other dietary supplements	0.0	0.1	0.1	-0.0	0.3
Eye problems/disorders: Glaucoma	0.0	0.0	0.0	0.2	-0.1
Medication: Atorvastatin	0.0	0.0	0.0	-0.2	-0.1
Ever depressed for a whole week	0.0	0.1	0.1	0.3	0.1
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.0	-0.0	-0.2

Hub : Genes

OLA1P1

Models

Trait associations