[Hub]/) : Traits : Arm fat percentage (left) :

chr8:8,092,025-12,751,157

Best TWAS P=9.49e-12 · Best GWAS P=2.41e-11 conditioned to 0.00134

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM86B1 0.02 0.02 lasso 3 0.01 1.3e-02 5.3 5.1 2.6e-07 0.52 0.02 0.93 FALSE
2 GTEx Adipose Subcutaneous ERI1 0.05 0.00 enet 10 0.00 5.5e-01 4.5 -5.8 6.6e-09 -0.59 0.11 0.67 FALSE
3 GTEx Adipose Subcutaneous AF131215.2 0.24 0.15 lasso 7 0.14 3.5e-11 -5.0 5.2 2.1e-07 0.49 0.76 0.24 FALSE
4 GTEx Adipose Subcutaneous FAM85A 0.06 0.06 enet 10 0.07 3.3e-06 -4.7 5.5 4.6e-08 0.39 0.13 0.82 FALSE
5 GTEx Adrenal Gland FAM86B3P 0.16 0.00 enet 18 0.03 2.2e-02 4.4 -5.3 1.3e-07 -0.31 0.06 0.17 FALSE
6 GTEx Adrenal Gland AF131215.2 0.20 0.16 enet 12 0.13 2.2e-05 4.8 5.2 1.5e-07 0.49 0.74 0.25 FALSE
7 GTEx Adrenal Gland AF131215.9 0.18 0.16 lasso 10 0.18 3.5e-07 4.8 5.3 1.2e-07 0.50 0.74 0.24 FALSE
8 GTEx Artery Aorta ERI1 0.11 0.08 lasso 5 0.10 5.1e-06 5.5 -5.1 2.9e-07 -0.49 0.21 0.78 FALSE
9 GTEx Artery Aorta AF131215.2 0.09 0.09 lasso 7 0.08 2.0e-05 -5.0 5.3 9.8e-08 0.51 0.57 0.39 FALSE
10 GTEx Artery Aorta AF131215.9 0.13 0.05 lasso 6 0.07 1.3e-04 5.2 5.2 1.7e-07 0.50 0.68 0.28 FALSE
11 GTEx Artery Coronary AF131215.2 0.11 0.02 enet 27 0.05 6.5e-03 -4.3 5.6 1.7e-08 0.43 0.08 0.65 FALSE
12 GTEx Artery Tibial ERI1 0.05 0.02 lasso 7 0.01 3.2e-02 4.9 -5.2 2.0e-07 -0.46 0.36 0.32 FALSE
13 GTEx Artery Tibial AF131215.2 0.07 0.03 enet 24 0.05 1.8e-04 -3.7 5.2 2.5e-07 0.42 0.08 0.91 FALSE
14 GTEx Artery Tibial FAM85A 0.09 0.06 enet 18 0.08 1.5e-06 -4.7 5.2 1.8e-07 0.41 0.11 0.85 FALSE
15 GTEx Brain Cortex FAM86B3P 0.14 0.05 enet 9 0.07 5.1e-03 4.4 -5.2 2.0e-07 -0.51 0.10 0.51 FALSE
16 GTEx Brain Frontal Cortex BA9 FAM86B3P 0.16 0.13 enet 27 0.10 1.1e-03 4.7 -5.3 1.1e-07 -0.47 0.04 0.87 FALSE
17 GTEx Breast Mammary Tissue AF131215.2 0.16 0.15 lasso 6 0.12 1.1e-06 -5.0 5.2 2.3e-07 0.53 0.71 0.24 FALSE
18 GTEx Cells Transformed fibroblasts ERI1 0.34 0.35 lasso 7 0.35 1.9e-27 5.5 -5.8 6.3e-09 -0.45 0.11 0.89 FALSE
19 GTEx Cells Transformed fibroblasts FAM86B3P 0.23 0.33 lasso 11 0.38 8.4e-30 4.7 5.1 2.8e-07 0.52 0.09 0.90 FALSE
20 GTEx Esophagus Gastroesophageal Junction MSRA 0.11 -0.01 enet 30 -0.01 8.0e-01 6.0 -5.7 1.2e-08 -0.49 0.15 0.21 FALSE
21 GTEx Esophagus Muscularis ERI1 0.12 0.09 enet 13 0.08 7.7e-06 4.3 -5.3 1.2e-07 -0.47 0.68 0.31 FALSE
22 GTEx Heart Atrial Appendage MFHAS1 0.34 0.23 enet 56 0.19 5.7e-09 -4.7 5.4 6.9e-08 0.32 0.29 0.70 FALSE
23 GTEx Heart Left Ventricle AF131215.2 0.05 0.01 enet 11 0.01 1.5e-01 4.8 5.1 2.8e-07 0.49 0.34 0.28 FALSE
24 GTEx Nerve Tibial ERI1 0.07 0.01 enet 16 0.01 4.2e-02 -3.8 -5.7 1.6e-08 -0.52 0.22 0.40 FALSE
25 GTEx Prostate AF131215.2 0.18 0.02 lasso 6 0.02 9.6e-02 3.0 5.2 2.0e-07 0.43 0.08 0.50 FALSE
26 GTEx Skin Sun Exposed Lower leg FAM85A 0.09 0.04 enet 28 0.04 1.4e-04 -4.7 5.9 2.9e-09 0.36 0.10 0.80 FALSE
27 GTEx Testis FAM86B3P 0.15 0.14 lasso 7 0.13 2.2e-06 4.4 -5.1 2.6e-07 -0.51 0.03 0.97 FALSE
28 GTEx Thyroid SGK223 0.19 0.35 enet 16 0.36 1.1e-28 4.8 -5.3 1.2e-07 -0.51 0.08 0.91 FALSE
29 NTR Blood MSRA 0.02 0.01 blup 833 0.01 2.3e-05 3.9 -6.8 9.5e-12 -0.61 0.54 0.45 TRUE
30 ROSMAP Brain Pre-frontal Cortex XKR6 0.11 0.10 enet 23 0.13 1.2e-16 -3.7 5.5 4.5e-08 0.52 0.88 0.11 FALSE
31 ROSMAP Brain Pre-frontal Cortex SGK223 0.07 0.02 blup 427 0.05 4.3e-07 3.1 5.2 1.7e-07 0.42 0.28 0.69 FALSE
32 ROSMAP Brain Pre-frontal Cortex RP11-481A20.11 0.06 0.04 blup 286 0.04 2.2e-06 4.1 5.6 2.5e-08 0.49 0.46 0.52 FALSE
33 The Cancer Genome Atlas Bladder Urothelial Carcinoma ERI1 0.05 0.01 blup 72 0.01 5.0e-02 5.5 -5.2 1.5e-07 -0.33 0.01 0.83 FALSE
34 The Cancer Genome Atlas Breast Invasive Carcinoma RP1L1 0.02 0.01 lasso 2 0.01 4.1e-03 4.5 5.2 2.3e-07 0.38 0.01 0.54 FALSE
35 The Cancer Genome Atlas Lung Adenocarcinoma ERI1 0.06 0.04 blup 72 0.04 1.5e-05 5.3 -5.4 8.1e-08 -0.40 0.01 0.99 FALSE