[Hub]/) : Traits : Arm predicted mass (left) :

chr5:129,797,129-132,839,137

Best TWAS P=5.04e-23 · Best GWAS P=9.41e-18 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PDLIM4 0.11 0.18 lasso 5 0.18 8.0e-21 -5.0 -5.3 1.3e-07 0.27 1.00 0.00 TRUE
2 GTEx Adipose Subcutaneous HINT1 0.10 0.07 enet 16 0.06 8.8e-06 -8.2 -9.9 5.0e-23 0.43 0.05 0.94 TRUE
3 GTEx Adipose Subcutaneous SLC22A5 0.05 0.04 lasso 4 0.04 4.2e-04 7.9 -6.2 4.4e-10 0.34 0.13 0.80 FALSE
4 GTEx Adipose Subcutaneous AC034220.3 0.11 0.11 lasso 10 0.09 4.8e-08 -6.5 6.5 6.3e-11 -0.36 0.99 0.01 FALSE
5 GTEx Adipose Visceral Omentum AC034220.3 0.10 0.09 lasso 7 0.08 7.3e-05 -6.5 6.5 7.9e-11 -0.36 0.55 0.10 FALSE
6 GTEx Adrenal Gland AC034220.3 0.12 0.11 lasso 16 0.08 7.7e-04 -6.5 6.5 7.2e-11 -0.34 0.72 0.06 FALSE
7 GTEx Artery Aorta P4HA2 0.12 0.14 lasso 2 0.11 1.2e-06 8.0 8.0 9.8e-16 -0.53 0.10 0.89 FALSE
8 GTEx Artery Aorta HINT1 0.07 0.07 enet 8 0.06 4.7e-04 -7.8 -8.8 1.2e-18 0.51 0.10 0.46 FALSE
9 GTEx Artery Aorta AC034220.3 0.08 0.06 lasso 3 0.05 1.1e-03 -6.6 7.5 8.4e-14 -0.29 0.58 0.11 FALSE
10 GTEx Artery Aorta P4HA2-AS1 0.08 0.03 lasso 3 0.01 6.6e-02 7.9 8.1 7.4e-16 -0.51 0.16 0.66 FALSE
11 GTEx Artery Tibial P4HA2 0.12 0.15 lasso 6 0.14 3.2e-11 8.1 8.6 1.1e-17 -0.54 0.07 0.93 FALSE
12 GTEx Artery Tibial HINT1 0.11 0.04 enet 18 0.06 1.0e-05 -7.8 -9.8 1.2e-22 0.73 0.07 0.89 FALSE
13 GTEx Artery Tibial LYRM7 0.10 0.03 lasso 3 0.04 3.1e-04 -5.7 5.2 1.8e-07 -0.43 0.51 0.09 FALSE
14 GTEx Artery Tibial SLC22A5 0.18 0.12 enet 8 0.12 2.5e-09 7.9 -7.0 3.0e-12 0.43 0.09 0.91 FALSE
15 GTEx Artery Tibial P4HA2-AS1 0.10 0.09 lasso 4 0.11 1.0e-08 8.2 7.9 3.0e-15 -0.46 0.09 0.91 FALSE
16 GTEx Brain Caudate basal ganglia AC034220.3 0.41 0.45 enet 19 0.46 8.8e-15 -6.5 6.9 6.2e-12 -0.36 0.99 0.01 FALSE
17 GTEx Brain Cortex AC034220.3 0.43 0.39 lasso 15 0.17 2.4e-05 -6.5 6.3 3.3e-10 -0.34 0.98 0.02 FALSE
18 GTEx Brain Frontal Cortex BA9 AC034220.3 0.31 0.20 lasso 14 0.21 3.3e-06 -6.8 5.3 9.4e-08 -0.38 0.64 0.22 FALSE
19 GTEx Brain Hippocampus AC034220.3 0.21 0.15 lasso 14 0.18 5.8e-05 -6.8 7.5 4.8e-14 -0.46 0.25 0.53 FALSE
20 GTEx Brain Nucleus accumbens basal ganglia SLC22A5 0.15 0.00 enet 24 0.05 1.4e-02 -6.7 5.2 1.5e-07 -0.60 0.05 0.58 FALSE
21 GTEx Brain Nucleus accumbens basal ganglia AC034220.3 0.24 0.24 enet 34 0.24 3.7e-07 -6.6 6.6 3.1e-11 -0.33 0.90 0.04 FALSE
22 GTEx Breast Mammary Tissue SLC22A5 0.10 0.02 enet 16 0.06 4.5e-04 8.2 -6.2 7.8e-10 0.61 0.23 0.67 TRUE
23 GTEx Breast Mammary Tissue (Female) SLC22A5 0.04 -0.01 lasso 3 0.01 1.3e-01 -4.2 -6.3 3.2e-10 0.46 0.05 0.20 FALSE
24 GTEx Cells EBV-transformed lymphocytes SLC22A5 0.37 0.05 lasso 13 0.10 2.8e-04 8.2 -7.3 2.6e-13 0.53 0.13 0.74 FALSE
25 GTEx Cells Transformed fibroblasts PDLIM4 0.08 0.09 lasso 1 0.07 6.4e-06 -5.1 -5.1 2.9e-07 0.27 0.83 0.02 FALSE
26 GTEx Cells Transformed fibroblasts HINT1 0.10 0.06 lasso 2 0.05 2.1e-04 -7.8 -8.5 1.8e-17 0.53 0.07 0.91 FALSE
27 GTEx Cells Transformed fibroblasts SLC22A5 0.32 0.28 lasso 7 0.35 1.6e-27 -6.4 -7.3 2.2e-13 0.34 0.44 0.56 FALSE
28 GTEx Colon Sigmoid AC034220.3 0.18 0.11 lasso 12 0.06 3.7e-03 -6.8 6.3 2.8e-10 -0.35 0.20 0.32 FALSE
29 GTEx Colon Transverse SLC22A5 0.12 0.07 enet 8 0.07 2.5e-04 8.2 -6.8 1.2e-11 0.32 0.15 0.73 FALSE
30 GTEx Colon Transverse AC034220.3 0.30 0.15 lasso 3 0.11 8.4e-06 -6.6 7.0 2.3e-12 -0.40 0.94 0.02 FALSE
31 GTEx Esophagus Gastroesophageal Junction SEPT8 0.22 0.08 lasso 12 0.10 2.2e-04 -5.8 6.4 1.3e-10 -0.24 0.32 0.52 TRUE
32 GTEx Esophagus Mucosa P4HA2 0.23 0.10 lasso 6 0.14 6.1e-10 8.0 7.8 4.3e-15 -0.45 0.12 0.88 FALSE
33 GTEx Esophagus Mucosa SLC22A5 0.16 0.16 enet 8 0.16 6.3e-11 8.2 -8.1 4.7e-16 0.51 0.06 0.94 FALSE
34 GTEx Esophagus Mucosa AC034220.3 0.08 0.03 lasso 3 0.05 4.7e-04 -6.8 6.7 2.9e-11 -0.35 0.96 0.02 FALSE
35 GTEx Esophagus Mucosa P4HA2-AS1 0.09 0.06 lasso 6 0.08 5.4e-06 8.0 7.6 2.8e-14 -0.50 0.18 0.80 FALSE
36 GTEx Esophagus Muscularis AC034220.3 0.12 0.08 enet 20 0.07 3.8e-05 -6.6 6.0 2.2e-09 -0.32 0.76 0.16 FALSE
37 GTEx Heart Atrial Appendage AC034220.3 0.16 0.09 enet 17 0.18 1.7e-08 -6.5 7.1 1.1e-12 -0.29 0.82 0.18 FALSE
38 GTEx Heart Left Ventricle AC034220.3 0.25 0.22 lasso 6 0.25 8.6e-14 -6.6 7.1 1.1e-12 -0.29 0.98 0.02 FALSE
39 GTEx Liver AC034220.3 0.30 0.16 lasso 6 0.16 3.9e-05 -6.5 5.2 1.7e-07 -0.25 0.59 0.04 FALSE
40 GTEx Lung SLC22A5 0.10 0.15 enet 11 0.13 3.4e-10 8.2 -7.8 6.3e-15 0.50 0.07 0.93 FALSE
41 GTEx Muscle Skeletal AC034220.3 0.27 0.23 lasso 9 0.24 9.1e-24 -6.5 6.7 2.6e-11 -0.36 1.00 0.00 FALSE
42 GTEx Muscle Skeletal MIR3936 0.04 0.01 lasso 4 0.00 9.9e-02 -5.1 6.7 1.7e-11 -0.37 0.18 0.29 FALSE
43 GTEx Nerve Tibial P4HA2 0.19 0.12 enet 26 0.14 6.2e-10 -6.5 7.4 1.3e-13 -0.54 0.14 0.86 FALSE
44 GTEx Nerve Tibial LYRM7 0.05 0.02 enet 11 0.04 7.0e-04 -5.7 5.3 1.1e-07 -0.47 0.33 0.39 FALSE
45 GTEx Nerve Tibial AC034220.3 0.15 0.11 lasso 5 0.10 1.9e-07 -6.5 6.7 1.6e-11 -0.37 1.00 0.00 FALSE
46 GTEx Nerve Tibial P4HA2-AS1 0.14 0.05 lasso 8 0.08 3.8e-06 7.2 8.1 5.2e-16 -0.59 0.22 0.78 FALSE
47 GTEx Ovary AC004041.2 0.21 -0.01 lasso 2 -0.01 7.7e-01 -4.6 6.2 6.3e-10 -0.13 0.06 0.26 FALSE
48 GTEx Pancreas P4HA2 0.22 0.21 lasso 13 0.20 5.3e-09 -5.1 6.5 9.5e-11 -0.54 0.50 0.48 FALSE
49 GTEx Pancreas P4HA2-AS1 0.16 0.16 lasso 5 0.16 3.2e-07 -5.1 5.8 6.9e-09 -0.54 0.48 0.44 TRUE
50 GTEx Pituitary AC034220.3 0.25 0.22 lasso 12 0.18 3.1e-05 -5.5 6.2 4.6e-10 -0.26 0.71 0.03 FALSE
51 GTEx Prostate AC034220.3 0.38 0.37 lasso 5 0.37 3.0e-10 -6.6 6.1 1.1e-09 -0.35 0.95 0.04 FALSE
52 GTEx Skin Not Sun Exposed Suprapubic PDLIM4 0.13 0.08 lasso 2 0.06 2.6e-04 8.2 -7.5 6.5e-14 0.35 0.13 0.77 FALSE
53 GTEx Skin Not Sun Exposed Suprapubic SLC22A4 0.13 0.00 lasso 4 0.01 7.1e-02 -2.3 -5.2 2.5e-07 0.51 0.13 0.22 FALSE
54 GTEx Skin Not Sun Exposed Suprapubic SLC22A5 0.13 0.05 lasso 8 0.05 8.3e-04 -6.6 -7.3 3.9e-13 0.39 0.41 0.58 FALSE
55 GTEx Skin Sun Exposed Lower leg PDLIM4 0.09 0.08 lasso 8 0.09 1.0e-07 8.0 -8.1 6.4e-16 0.45 0.11 0.89 TRUE
56 GTEx Skin Sun Exposed Lower leg SLC22A5 0.25 0.21 lasso 3 0.20 1.4e-16 7.9 -8.0 1.3e-15 0.47 0.09 0.91 FALSE
57 GTEx Spleen SLC22A5 0.26 0.28 lasso 4 0.28 6.6e-08 8.2 8.3 7.9e-17 -0.48 0.06 0.84 FALSE
58 GTEx Stomach SLC22A5 0.09 0.04 lasso 4 0.01 9.0e-02 -6.0 -6.6 3.5e-11 0.23 0.13 0.24 FALSE
59 GTEx Stomach AC034220.3 0.17 0.15 enet 21 0.16 4.2e-08 -5.6 6.7 2.7e-11 -0.28 1.00 0.00 FALSE
60 GTEx Testis P4HA2 0.14 0.13 lasso 5 0.11 1.4e-05 8.0 8.2 2.3e-16 -0.54 0.14 0.85 FALSE
61 GTEx Testis PDLIM4 0.15 0.07 enet 8 0.05 2.5e-03 -6.8 7.2 6.0e-13 -0.45 0.25 0.13 FALSE
62 GTEx Testis RAPGEF6 0.50 0.35 lasso 4 0.32 6.5e-15 -7.5 -7.8 5.9e-15 0.54 0.96 0.04 FALSE
63 GTEx Testis AC034220.3 0.15 0.12 lasso 9 0.12 4.4e-06 -6.5 6.5 8.6e-11 -0.36 0.84 0.07 FALSE
64 GTEx Thyroid P4HA2 0.08 0.07 enet 9 0.06 3.5e-05 8.1 7.2 5.8e-13 -0.47 0.08 0.90 FALSE
65 GTEx Thyroid PDLIM4 0.05 0.02 enet 5 0.01 3.1e-02 7.2 -7.1 1.0e-12 0.49 0.19 0.60 FALSE
66 GTEx Thyroid P4HA2-AS1 0.08 0.06 enet 14 0.05 1.6e-04 8.1 7.3 3.7e-13 -0.42 0.09 0.88 FALSE
67 GTEx Whole Blood SLC22A4 0.07 0.05 enet 16 0.05 4.6e-05 -6.4 -7.1 1.4e-12 0.26 0.27 0.55 FALSE
68 GTEx Whole Blood SLC22A5 0.09 0.12 lasso 2 0.10 1.7e-09 8.2 -8.2 3.6e-16 0.47 0.04 0.96 FALSE
69 GTEx Whole Blood AC034220.3 0.08 0.05 enet 31 0.06 4.0e-06 7.9 -7.5 4.7e-14 0.30 0.18 0.81 FALSE
70 GTEx Whole Blood AC116366.6 0.05 0.04 lasso 17 0.03 5.7e-04 -4.1 5.4 6.1e-08 -0.48 0.46 0.19 FALSE
71 METSIM Adipose P4HA2 0.09 0.08 lasso 12 0.09 2.4e-13 8.2 8.1 4.9e-16 -0.60 0.09 0.91 FALSE
72 METSIM Adipose PDLIM4 0.05 0.04 lasso 4 0.02 2.8e-04 7.3 -7.2 8.5e-13 0.45 0.85 0.08 FALSE
73 METSIM Adipose SLC22A5 0.05 0.08 lasso 1 0.08 1.0e-11 8.2 -8.2 3.5e-16 0.47 0.07 0.93 FALSE
74 NTR Blood SLC22A4 0.02 0.00 blup 423 0.01 5.2e-04 4.0 -6.9 6.3e-12 0.39 0.30 0.64 FALSE
75 ROSMAP Brain Pre-frontal Cortex PDLIM4 0.25 0.27 lasso 4 0.26 2.7e-33 -5.1 -5.8 7.8e-09 0.32 1.00 0.00 FALSE
76 ROSMAP Brain Pre-frontal Cortex SLC22A4 0.03 0.05 lasso 2 0.04 1.2e-05 -7.7 -8.0 1.1e-15 0.36 0.56 0.35 FALSE
77 YFS Blood CDC42SE2 0.14 0.05 lasso 9 0.07 3.1e-22 -7.5 5.5 4.6e-08 -0.32 0.88 0.12 FALSE
78 YFS Blood SLC22A4 0.10 0.12 enet 47 0.14 5.1e-42 -6.5 -5.3 1.3e-07 0.32 1.00 0.00 FALSE
79 YFS Blood SLC22A5 0.38 0.36 bslmm 430 0.37 3.0e-128 8.2 -9.0 2.0e-19 0.47 0.04 0.96 FALSE
80 The Cancer Genome Atlas Breast Invasive Carcinoma P4HA2 0.03 0.02 blup 47 0.03 3.1e-06 8.2 7.8 8.9e-15 -0.59 0.00 1.00 FALSE
81 The Cancer Genome Atlas Breast Invasive Carcinoma SLC22A4 0.05 0.01 enet 7 0.02 1.6e-05 8.2 -6.2 5.5e-10 0.30 0.01 0.98 FALSE
82 The Cancer Genome Atlas Breast Invasive Carcinoma SLC22A5 0.05 0.07 enet 11 0.09 5.3e-17 -5.6 -6.8 1.4e-11 0.25 1.00 0.00 FALSE
83 The Cancer Genome Atlas Colon Adenocarcinoma SLC22A5 0.08 0.04 blup 92 0.07 1.2e-04 -6.4 -6.7 1.7e-11 0.34 0.03 0.91 FALSE
84 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SLC22A4 0.02 0.02 lasso 1 0.02 3.0e-03 -5.8 -5.8 6.8e-09 0.18 0.14 0.46 FALSE
85 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SLC22A5 0.06 0.05 blup 93 0.08 1.2e-09 -6.6 -6.8 1.1e-11 0.31 0.07 0.93 TRUE
86 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PDLIM4 0.09 0.02 lasso 6 0.05 4.5e-06 -4.6 -6.2 7.6e-10 0.32 0.22 0.59 FALSE
87 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC22A4 0.03 0.03 lasso 1 0.02 3.5e-03 -6.6 -6.6 3.3e-11 0.35 0.32 0.34 FALSE
88 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SLC22A4 0.04 0.03 blup 108 0.01 7.1e-02 -5.6 -5.6 2.2e-08 0.18 0.11 0.20 FALSE
89 The Cancer Genome Atlas Brain Lower Grade Glioma HINT1 0.06 0.03 enet 5 0.03 5.2e-04 -5.7 -6.7 1.7e-11 0.38 0.08 0.41 FALSE
90 The Cancer Genome Atlas Lung Adenocarcinoma LYRM7 0.03 0.01 enet 10 0.02 7.5e-04 -5.7 8.2 3.2e-16 -0.66 0.01 0.90 FALSE
91 The Cancer Genome Atlas Lung Adenocarcinoma SLC22A5 0.06 0.03 lasso 4 0.02 9.3e-04 -6.4 -6.8 1.3e-11 0.28 0.06 0.72 FALSE
92 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SLC22A5 0.05 0.03 blup 93 0.05 1.9e-06 -5.6 -6.7 1.6e-11 0.25 0.04 0.96 FALSE
93 The Cancer Genome Atlas Prostate Adenocarcinoma PDLIM4 0.32 0.36 enet 13 0.37 3.8e-40 -4.6 -5.8 4.8e-09 0.30 1.00 0.00 FALSE
94 The Cancer Genome Atlas Prostate Adenocarcinoma SLC22A4 0.09 0.07 blup 108 0.09 3.0e-09 -6.5 -7.1 9.3e-13 0.40 0.08 0.92 FALSE
95 The Cancer Genome Atlas Prostate Adenocarcinoma SLC22A5 0.12 0.05 lasso 4 0.08 1.8e-08 -4.2 -5.4 5.7e-08 0.18 0.96 0.00 FALSE
96 The Cancer Genome Atlas Thyroid Carcinoma C5orf56 0.06 0.04 blup 98 0.03 1.3e-03 -4.2 7.4 1.6e-13 -0.43 0.79 0.12 FALSE
97 The Cancer Genome Atlas Thyroid Carcinoma HINT1 0.07 0.04 lasso 2 0.01 1.8e-02 -7.3 -7.3 3.1e-13 0.50 0.00 0.98 FALSE
98 The Cancer Genome Atlas Thyroid Carcinoma IRF1 0.05 0.02 blup 83 0.03 1.5e-03 5.6 6.7 2.5e-11 -0.38 0.05 0.11 FALSE
99 The Cancer Genome Atlas Thyroid Carcinoma P4HA2 0.21 0.35 enet 10 0.35 4.7e-35 8.2 7.9 2.7e-15 -0.52 0.00 1.00 FALSE
100 The Cancer Genome Atlas Thyroid Carcinoma SLC22A5 0.03 0.02 lasso 1 0.01 2.6e-02 -6.4 -6.4 1.9e-10 0.27 0.02 0.71 FALSE