[Hub]/) : Traits : Trunk fat-free mass : ← →

chr12:110,233,500-113,517,494

Best TWAS P=2.42e-16 · Best GWAS P=8.05e-24 conditioned to 0.134

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Artery Tibial	HECTD4	0.05	0.02	lasso	3	0.01	3.1e-02	-8.6	-8.2	2.4e-16	0.78	0.01	0.92	TRUE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	CUX2	0.08	0.01	blup	95	0.02	1.3e-03	4.8	6.6	4.1e-11	-0.15	0.08	0.57	TRUE
5	GTEx	Breast Mammary Tissue (Female)	VPS29	0.10	-0.01	lasso	2	0.02	1.0e-01	-4.7	5.8	8.3e-09	-0.34	0.03	0.15	TRUE
13	YFS	Blood	SH2B3	0.05	0.01	enet	22	0.02	3.3e-07	3.9	-6.6	4.7e-11	0.64	0.67	0.33	FALSE
2	GTEx	Adipose Subcutaneous	HECTD4	0.06	0.00	enet	15	0.02	1.0e-02	3.8	-6.6	5.3e-11	0.65	0.06	0.84	FALSE
6	GTEx	Colon Transverse	FAM109A	0.21	0.00	lasso	4	0.01	1.3e-01	5.6	-6.5	8.7e-11	0.41	0.06	0.06	FALSE
9	GTEx	Skin Sun Exposed Lower leg	ALDH2	0.10	0.09	enet	13	0.13	6.7e-11	3.6	-6.5	1.0e-10	0.62	0.98	0.02	FALSE
7	GTEx	Nerve Tibial	HECTD4	0.05	0.01	enet	6	0.01	3.6e-02	5.8	-6.0	2.3e-09	0.41	0.23	0.45	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	ACAD10	0.02	0.02	lasso	3	0.01	7.0e-03	5.9	5.9	3.3e-09	-0.50	0.01	0.91	FALSE
12	NTR	Blood	ALDH2	0.06	0.01	blup	222	0.02	4.3e-08	3.6	5.9	4.0e-09	-0.43	0.99	0.00	FALSE
10	GTEx	Thyroid	BRAP	0.07	0.02	lasso	7	0.03	1.1e-03	3.9	5.7	9.0e-09	-0.54	0.38	0.38	FALSE
17	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ERP29	0.11	0.03	blup	25	0.05	5.0e-03	3.7	5.7	1.5e-08	-0.60	0.01	0.75	FALSE
3	GTEx	Adrenal Gland	PPTC7	0.13	-0.01	lasso	6	0.00	3.4e-01	4.2	5.5	4.0e-08	-0.26	0.04	0.13	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	ALDH2	0.07	0.03	lasso	4	0.06	3.9e-04	3.1	-5.3	1.1e-07	0.44	0.02	0.90	FALSE
11	GTEx	Thyroid	VPS29	0.07	0.01	lasso	5	0.01	8.9e-02	4.6	5.2	1.6e-07	-0.11	0.09	0.16	FALSE
14	YFS	Blood	TRAFD1	0.04	0.02	lasso	2	0.01	2.9e-05	-4.0	-5.2	1.7e-07	0.55	0.09	0.85	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ATXN2	0.02	0.03	enet	8	0.02	4.8e-04	4.9	-5.2	1.8e-07	0.56	0.27	0.63	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	MAPKAPK5-AS1	0.04	0.00	enet	30	0.00	7.0e-01	3.8	5.2	2.4e-07	-0.53	0.21	0.17	FALSE