[Hub]/) : Traits : Trunk fat-free mass :

chr12:110,233,500-113,517,494

Best TWAS P=2.42e-16 · Best GWAS P=8.05e-24 conditioned to 0.134

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ATXN2 0.02 0.03 enet 8 0.02 4.8e-04 4.9 -5.2 1.8e-07 0.56 0.27 0.63 FALSE
2 GTEx Adipose Subcutaneous HECTD4 0.06 0.00 enet 15 0.02 1.0e-02 3.8 -6.6 5.3e-11 0.65 0.06 0.84 FALSE
3 GTEx Adrenal Gland PPTC7 0.13 -0.01 lasso 6 0.00 3.4e-01 4.2 5.5 4.0e-08 -0.26 0.04 0.13 FALSE
4 GTEx Artery Tibial HECTD4 0.05 0.02 lasso 3 0.01 3.1e-02 -8.6 -8.2 2.4e-16 0.78 0.01 0.92 TRUE
5 GTEx Breast Mammary Tissue (Female) VPS29 0.10 -0.01 lasso 2 0.02 1.0e-01 -4.7 5.8 8.3e-09 -0.34 0.03 0.15 TRUE
6 GTEx Colon Transverse FAM109A 0.21 0.00 lasso 4 0.01 1.3e-01 5.6 -6.5 8.7e-11 0.41 0.06 0.06 FALSE
7 GTEx Nerve Tibial HECTD4 0.05 0.01 enet 6 0.01 3.6e-02 5.8 -6.0 2.3e-09 0.41 0.23 0.45 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic MAPKAPK5-AS1 0.04 0.00 enet 30 0.00 7.0e-01 3.8 5.2 2.4e-07 -0.53 0.21 0.17 FALSE
9 GTEx Skin Sun Exposed Lower leg ALDH2 0.10 0.09 enet 13 0.13 6.7e-11 3.6 -6.5 1.0e-10 0.62 0.98 0.02 FALSE
10 GTEx Thyroid BRAP 0.07 0.02 lasso 7 0.03 1.1e-03 3.9 5.7 9.0e-09 -0.54 0.38 0.38 FALSE
11 GTEx Thyroid VPS29 0.07 0.01 lasso 5 0.01 8.9e-02 4.6 5.2 1.6e-07 -0.11 0.09 0.16 FALSE
12 NTR Blood ALDH2 0.06 0.01 blup 222 0.02 4.3e-08 3.6 5.9 4.0e-09 -0.43 0.99 0.00 FALSE
13 YFS Blood SH2B3 0.05 0.01 enet 22 0.02 3.3e-07 3.9 -6.6 4.7e-11 0.64 0.67 0.33 FALSE
14 YFS Blood TRAFD1 0.04 0.02 lasso 2 0.01 2.9e-05 -4.0 -5.2 1.7e-07 0.55 0.09 0.85 FALSE
15 The Cancer Genome Atlas Colon Adenocarcinoma ALDH2 0.07 0.03 lasso 4 0.06 3.9e-04 3.1 -5.3 1.1e-07 0.44 0.02 0.90 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma ACAD10 0.02 0.02 lasso 3 0.01 7.0e-03 5.9 5.9 3.3e-09 -0.50 0.01 0.91 FALSE
17 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ERP29 0.11 0.03 blup 25 0.05 5.0e-03 3.7 5.7 1.5e-08 -0.60 0.01 0.75 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma CUX2 0.08 0.01 blup 95 0.02 1.3e-03 4.8 6.6 4.1e-11 -0.15 0.08 0.57 TRUE