[Hub]/) : Traits : Diastolic blood pressure, automated reading : ← →

chr17:6,397,773-8,484,683

Best TWAS P=1.51e-10 · Best GWAS P=3.66e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	SLC2A4	0.08	0.06	lasso	2	0.08	1.2e-09	-4.0	5.3	1.2e-07	0.04	0.32	0.66	FALSE
2	GTEx	Artery Aorta	ACADVL	0.10	0.09	lasso	3	0.10	2.4e-06	-5.3	-5.1	2.7e-07	-0.05	0.08	0.92	FALSE
3	GTEx	Artery Tibial	ACADVL	0.12	0.10	enet	3	0.10	2.7e-08	-5.1	-5.2	1.6e-07	-0.04	0.08	0.92	FALSE
4	GTEx	Colon Transverse	LSMD1	0.28	0.12	lasso	5	0.19	3.3e-09	6.3	5.6	1.6e-08	0.89	0.00	1.00	FALSE
5	GTEx	Muscle Skeletal	DLG4	0.12	0.05	lasso	4	0.05	2.3e-05	-5.3	5.6	2.2e-08	0.03	0.06	0.94	FALSE
6	GTEx	Skin Sun Exposed Lower leg	DVL2	0.10	0.03	lasso	2	0.02	1.5e-02	-5.3	-5.6	2.6e-08	-0.05	0.02	0.98	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	YBX2	0.11	0.10	bslmm	442	0.10	2.5e-12	-4.8	-5.3	1.3e-07	-0.10	0.47	0.52	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	KDM6B	0.07	0.05	lasso	4	0.04	2.7e-06	6.2	-5.4	8.4e-08	-0.95	0.00	1.00	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	SLC2A4	0.08	0.08	enet	9	0.08	5.5e-11	-5.6	5.3	1.5e-07	0.02	0.02	0.98	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	CLDN7	0.07	0.06	lasso	4	0.05	3.9e-07	-5.4	-5.3	1.3e-07	-0.04	0.07	0.93	FALSE
11	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	EIF5A	0.05	0.04	blup	52	0.03	1.5e-03	3.7	-5.2	2.0e-07	-0.10	0.04	0.05	TRUE
12	The Cancer Genome Atlas	Colon Adenocarcinoma	CYB5D1	0.14	0.12	lasso	1	0.10	1.7e-06	6.3	-6.3	3.7e-10	-1.00	0.00	1.00	TRUE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DULLARD	0.03	0.03	blup	42	0.03	9.3e-05	-5.4	5.2	1.6e-07	0.06	0.06	0.91	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	C17orf81	0.04	0.05	enet	8	0.04	1.2e-05	-5.6	-6.4	1.5e-10	-0.09	0.00	1.00	TRUE
15	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	DULLARD	0.07	0.02	blup	42	0.06	2.3e-03	6.0	5.3	1.4e-07	0.07	0.00	0.95	FALSE