[Hub]/) : Traits : Systolic blood pressure, automated reading :

chr10:74,714,177-77,160,682

Best TWAS P=5.91e-15 · Best GWAS P=1.55e-11 conditioned to 0.114

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex VCL 0.07 0.05 lasso 4 0.06 6.0e-08 -5.9 -6.1 9.6e-10 -0.10 0.52 0.48 FALSE
2 GTEx Adipose Visceral Omentum FUT11 0.11 0.06 lasso 6 0.11 1.9e-06 6.2 -7.8 5.9e-15 -0.72 0.05 0.85 TRUE
3 GTEx Colon Transverse ADK 0.25 0.14 lasso 9 0.12 1.6e-06 5.1 5.6 2.1e-08 0.08 0.84 0.15 FALSE
4 GTEx Heart Atrial Appendage MYOZ1 0.43 0.25 lasso 11 0.38 5.4e-18 6.2 6.7 1.6e-11 0.84 0.03 0.97 FALSE
5 GTEx Heart Atrial Appendage FUT11 0.13 0.02 enet 22 0.10 4.7e-05 5.2 -5.8 5.7e-09 -0.71 0.06 0.86 FALSE
6 GTEx Nerve Tibial AP3M1 0.06 0.02 lasso 2 0.02 2.6e-02 5.1 5.2 2.1e-07 0.04 0.19 0.04 FALSE
7 GTEx Pancreas AGAP5 0.13 0.05 lasso 5 0.06 1.8e-03 3.8 5.8 6.4e-09 0.28 0.12 0.16 FALSE
8 ROSMAP Brain Pre-frontal Cortex MYOZ1 0.04 0.01 blup 235 0.02 2.6e-03 6.3 -6.4 1.7e-10 -0.70 0.05 0.87 FALSE
9 ROSMAP Brain Pre-frontal Cortex AP3M1 0.02 0.01 blup 231 0.02 1.3e-03 -6.0 7.2 5.2e-13 0.36 0.08 0.25 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SEC24C 0.07 0.07 blup 29 0.07 9.4e-05 6.3 -6.2 6.6e-10 -0.85 0.01 0.96 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma SEC24C 0.02 0.01 enet 4 0.01 8.5e-03 6.2 -5.8 7.3e-09 -0.82 0.01 0.80 FALSE
12 The Cancer Genome Atlas Lung Squamous Cell Carcinoma BMS1P4 0.02 0.01 blup 23 0.01 8.6e-03 3.4 -5.6 2.2e-08 -0.73 0.01 0.47 FALSE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SYNPO2L 0.01 0.02 enet 4 0.02 4.3e-03 6.7 -6.9 6.3e-12 -0.91 0.00 0.74 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma NDST2 0.03 0.02 blup 37 0.02 3.3e-03 4.4 5.8 5.8e-09 0.82 0.01 0.96 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma BMS1P4 0.07 0.08 blup 23 0.10 8.3e-10 3.4 -5.8 5.6e-09 -0.73 0.22 0.78 FALSE