[Hub]/) : Traits : Hand grip strength (left) :

chr11:46,622,392-48,485,877

Best TWAS P=1.1e-13 · Best GWAS P=1.29e-12 conditioned to 0.146

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM180B 0.07 0.08 lasso 3 0.08 9.1e-10 -6.8 -6.5 8.3e-11 -0.48 0.44 0.56 FALSE
2 CommonMind Brain Pre-frontal Cortex MTCH2 0.03 0.00 bslmm 299 0.00 1.1e-01 1.6 -6.7 2.5e-11 -0.33 0.08 0.46 FALSE
3 GTEx Adipose Subcutaneous C1QTNF4 0.16 0.22 lasso 4 0.22 2.5e-18 -6.8 6.6 3.0e-11 0.50 0.11 0.89 FALSE
4 GTEx Artery Aorta C1QTNF4 0.09 0.10 lasso 1 0.08 3.2e-05 -6.8 6.8 1.4e-11 0.49 0.15 0.76 FALSE
5 GTEx Brain Cortex MTCH2 0.21 0.19 lasso 6 0.16 4.0e-05 -6.4 -5.5 3.5e-08 -0.31 0.35 0.19 FALSE
6 GTEx Brain Cortex C1QTNF4 0.26 0.04 lasso 8 0.02 1.2e-01 6.8 6.8 8.3e-12 0.70 0.04 0.26 FALSE
7 GTEx Breast Mammary Tissue C1QTNF4 0.10 0.06 lasso 2 0.03 8.5e-03 -5.6 5.4 6.4e-08 0.38 0.27 0.16 FALSE
8 GTEx Breast Mammary Tissue (Female) MADD 0.13 0.04 lasso 3 0.05 1.3e-02 -5.6 -5.7 9.1e-09 -0.47 0.07 0.08 FALSE
9 GTEx Cells Transformed fibroblasts FNBP4 0.11 0.05 lasso 8 0.08 1.6e-06 6.9 -6.9 4.5e-12 -0.65 0.04 0.96 FALSE
10 GTEx Cells Transformed fibroblasts NDUFS3 0.08 0.01 lasso 2 0.01 3.3e-02 -6.8 6.7 2.4e-11 0.41 0.08 0.61 FALSE
11 GTEx Colon Transverse C1QTNF4 0.07 0.02 lasso 6 0.03 2.0e-02 -6.8 6.7 2.2e-11 0.48 0.18 0.43 FALSE
12 GTEx Esophagus Mucosa C1QTNF4 0.10 0.11 lasso 1 0.10 5.0e-07 -6.8 6.8 1.4e-11 0.49 0.10 0.89 FALSE
13 GTEx Esophagus Muscularis MTCH2 0.09 0.04 lasso 6 0.02 1.8e-02 -6.2 -6.0 1.9e-09 -0.64 0.40 0.30 FALSE
14 GTEx Esophagus Muscularis C1QTNF4 0.10 0.05 enet 23 0.06 1.4e-04 -6.8 7.1 1.7e-12 0.42 0.14 0.84 FALSE
15 GTEx Heart Atrial Appendage C1QTNF4 0.26 0.14 lasso 9 0.17 3.9e-08 -6.8 6.8 1.4e-11 0.53 0.34 0.65 FALSE
16 GTEx Heart Left Ventricle C1QTNF4 0.10 0.11 lasso 1 0.09 1.1e-05 -6.8 6.8 1.4e-11 0.49 0.11 0.69 FALSE
17 GTEx Liver PSMC3 0.15 0.09 lasso 4 0.07 5.9e-03 -4.8 -5.6 2.7e-08 -0.34 0.08 0.18 FALSE
18 GTEx Liver C1QTNF4 0.25 0.14 enet 16 0.20 2.3e-06 -6.8 6.6 4.9e-11 0.76 0.19 0.66 FALSE
19 GTEx Lung C1QTNF4 0.18 0.15 lasso 6 0.13 3.2e-10 -5.5 6.2 6.3e-10 0.45 0.73 0.27 FALSE
20 GTEx Muscle Skeletal MTCH2 0.05 0.03 enet 15 0.04 1.5e-04 -6.1 -5.7 9.0e-09 -0.36 0.58 0.32 FALSE
21 GTEx Muscle Skeletal C1QTNF4 0.09 0.14 lasso 3 0.13 9.9e-13 -6.8 6.9 7.0e-12 0.49 0.12 0.88 FALSE
22 GTEx Nerve Tibial CELF1 0.08 0.02 enet 15 0.06 4.3e-05 6.7 -5.1 2.8e-07 -0.76 0.07 0.70 FALSE
23 GTEx Nerve Tibial C1QTNF4 0.20 0.23 enet 12 0.23 1.7e-16 -6.8 6.2 5.8e-10 0.40 0.10 0.90 FALSE
24 GTEx Pituitary MADD 0.42 0.32 lasso 6 0.39 8.9e-11 3.0 -5.4 8.3e-08 -0.76 0.27 0.60 FALSE
25 GTEx Skin Not Sun Exposed Suprapubic C1QTNF4 0.32 0.18 enet 33 0.20 5.2e-11 -6.8 6.6 3.9e-11 0.46 0.12 0.88 FALSE
26 GTEx Skin Sun Exposed Lower leg C1QTNF4 0.25 0.22 lasso 12 0.23 4.2e-19 -6.8 7.2 7.1e-13 0.58 0.14 0.86 FALSE
27 GTEx Spleen C1QTNF4 0.31 0.28 enet 29 0.34 1.8e-09 -6.4 7.3 2.5e-13 0.58 0.22 0.77 FALSE
28 GTEx Testis MTCH2 0.17 0.16 lasso 3 0.16 1.0e-07 -5.6 -5.6 2.4e-08 -0.41 0.90 0.09 FALSE
29 GTEx Testis C1QTNF4 0.14 0.12 lasso 4 0.11 1.6e-05 7.0 6.6 3.4e-11 0.72 0.04 0.96 FALSE
30 GTEx Whole Blood C1QTNF4 0.09 0.05 lasso 3 0.03 1.4e-03 -6.4 6.4 1.7e-10 0.42 0.47 0.27 FALSE
31 METSIM Adipose C1QTNF4 0.24 0.31 lasso 7 0.31 1.2e-46 -6.2 6.1 1.3e-09 0.41 0.82 0.18 FALSE
32 NTR Blood MTCH2 0.02 0.04 lasso 1 0.04 1.3e-11 -6.2 6.2 5.1e-10 0.44 0.76 0.24 FALSE
33 ROSMAP Brain Pre-frontal Cortex MTCH2 0.35 0.40 enet 9 0.40 4.7e-56 -6.2 -6.4 1.6e-10 -0.45 0.82 0.18 FALSE
34 ROSMAP Brain Pre-frontal Cortex FNBP4 0.04 0.04 lasso 3 0.04 8.2e-06 7.0 -7.4 1.1e-13 -0.85 0.04 0.96 TRUE
35 ROSMAP Brain Pre-frontal Cortex PSMC3 0.15 0.08 bslmm 285 0.10 5.1e-13 2.4 -5.4 5.9e-08 -0.06 0.98 0.02 FALSE
36 ROSMAP Brain Pre-frontal Cortex C1QTNF4 0.05 0.06 blup 281 0.06 1.7e-08 -5.6 6.1 1.4e-09 0.18 0.73 0.27 FALSE
37 YFS Blood PSMC3 0.02 0.01 blup 289 0.01 2.8e-05 -6.8 -6.3 2.4e-10 -0.17 0.20 0.71 FALSE
38 YFS Blood PTPMT1 0.03 0.01 lasso 5 0.01 3.2e-04 6.9 5.4 5.3e-08 0.39 0.05 0.93 FALSE
39 The Cancer Genome Atlas Bladder Urothelial Carcinoma C1QTNF4 0.06 0.07 lasso 2 0.06 4.9e-06 -6.2 6.5 5.8e-11 0.46 0.02 0.97 FALSE
40 The Cancer Genome Atlas Colon Adenocarcinoma C1QTNF4 0.12 0.12 lasso 1 0.12 1.6e-07 -6.8 6.8 1.4e-11 0.49 0.00 1.00 FALSE
41 The Cancer Genome Atlas Colon Adenocarcinoma NUP160 0.05 0.05 blup 44 0.05 7.7e-04 7.0 -7.2 4.4e-13 -0.65 0.02 0.84 FALSE
42 The Cancer Genome Atlas Colon Adenocarcinoma PSMC3 0.09 0.05 blup 39 0.05 1.0e-03 3.3 -5.3 1.2e-07 -0.64 0.04 0.54 FALSE
43 The Cancer Genome Atlas Esophageal Carcinoma C1QTNF4 0.39 0.33 blup 15 0.35 6.1e-12 -6.8 6.6 2.9e-11 0.44 0.01 0.99 FALSE
44 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C1QTNF4 0.06 0.08 lasso 3 0.08 7.5e-09 -6.2 6.2 4.6e-10 0.44 0.08 0.92 FALSE
45 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C1QTNF4 0.12 0.14 enet 4 0.16 6.5e-18 -6.2 6.6 3.5e-11 0.47 0.08 0.92 FALSE
46 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C1QTNF4 0.13 0.16 lasso 1 0.16 3.1e-09 -6.2 6.2 5.1e-10 0.44 0.11 0.89 FALSE
47 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PSMC3 0.07 0.07 enet 7 0.06 1.4e-04 -5.6 -5.6 2.0e-08 -0.42 0.26 0.36 FALSE
48 The Cancer Genome Atlas Brain Lower Grade Glioma MTCH2 0.11 0.11 lasso 2 0.10 6.4e-12 -6.2 -6.2 5.1e-10 -0.43 0.45 0.55 FALSE
49 The Cancer Genome Atlas Brain Lower Grade Glioma PSMC3 0.10 0.05 blup 39 0.08 3.7e-09 -5.6 -6.0 2.0e-09 -0.16 0.96 0.03 FALSE
50 The Cancer Genome Atlas Liver Hepatocellular Carcinoma C1QTNF4 0.19 0.19 lasso 3 0.19 3.2e-09 -6.2 6.2 5.1e-10 0.43 0.10 0.90 FALSE
51 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PSMC3 0.09 0.07 blup 39 0.06 8.7e-04 -5.6 -5.3 1.2e-07 -0.33 0.56 0.08 FALSE
52 The Cancer Genome Atlas Lung Adenocarcinoma C1QTNF4 0.03 0.02 blup 15 0.02 1.3e-03 -6.8 7.1 1.2e-12 0.59 0.01 0.90 FALSE
53 The Cancer Genome Atlas Prostate Adenocarcinoma NUP160 0.03 0.02 enet 7 0.02 6.3e-03 -6.1 -6.7 1.9e-11 -0.61 0.06 0.40 FALSE
54 The Cancer Genome Atlas Stomach Adenocarcinoma C1QTNF4 0.06 0.04 lasso 4 0.03 4.3e-03 -6.2 6.5 9.8e-11 0.45 0.02 0.76 FALSE
55 The Cancer Genome Atlas Thyroid Carcinoma C1QTNF4 0.04 0.01 blup 15 0.03 7.9e-04 -6.8 5.9 3.6e-09 0.52 0.01 0.81 FALSE