TWAS hub - FAM106A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.054	0.0240	3.4e-03	0.012	0.021	0.018	0.022	0.017	1.0e-02	1.3e-03	2.4e-03	8.7e-04	3.3e-03
2	METSIM	Adipose	0.197	0.0487	4.2e-14	0.127	0.119	0.151	0.143	0.142	1.8e-18	2.3e-17	5.8e-22	9.5e-21	1.2e-20

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Age at first live birth	6.5	11.5	19.4	-1.9	-4.4
Birth weight of first child	6.2	11.2	20.1	-4.5	-1.5
Tinnitus: Yes, but not now, but have in the past	5.7	6.1	9.8	-1.6	3.1
Comparative height size at age 10	5.1	27.9	49.8	2.5	7.1
Depression (Nagel 2018)	4.8	7.2	8.3	-2.9	-2.5
Qualifications: None of the above	4.7	10.1	15.2	2.3	3.9
Length of working week for main job	4.7	5.2	7.0	2.6	1.8
Had other major operations	4.6	5.6	10.7	3.3	0.7
Had major operations	4.5	5.3	8.2	-2.9	-1.6
Fasting Glucose	4.4	5.3	6.3	-2.5	-2.1
Medication: Simvastatin	4.2	6.1	11.2	-3.3	-1.0
Standing height	4.2	41.6	49.1	5.8	7.0
Height	3.9	75.4	81.4	8.3	9.0
Lupus	3.6	5.4	10.8	0.4	3.3
Cholesterol lowering medication	3.6	5.3	9.5	-3.1	-1.0
Alcohol drinker status: Never	3.4	4.1	6.6	1.3	2.6
Fractured/broken bones in last 5 years	3.4	4.4	4.6	2.1	2.1
Waist Hip Ratio (WHR)	3.3	15.0	29.5	0.7	5.4
Seen doctor (GP) for nerves, anxiety, tension or depression	3.3	5.0	6.5	-1.9	-2.5
Age at last live birth	3.3	4.8	7.2	-1.6	-2.7
Mouth/teeth dental problems: Loose teeth	3.2	3.8	5.1	-1.6	-2.3
Qualifications: College or University degree	3.0	9.4	18.7	0.1	-4.3
Basal cell carcinoma (self-reported)	3.0	3.5	4.9	-1.5	-2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	2.9	3.9	6.1	-1.3	-2.5
Supplements: Glucosamine	2.9	3.8	4.3	-1.8	-2.1
Exposure to tobacco smoke outside home	2.9	3.9	7.5	2.7	0.6
Alzheimer’s Disease (including proxy)	2.7	4.0	7.6	-2.8	-0.5
Verbal and Numeric Reasoning (VNR)	2.7	6.5	11.0	-1.4	-3.3
Type 2 Diabetes (T2D) (2012)	2.7	3.1	5.2	-1.0	2.3
Blood Red Count	2.7	26.3	27.0	5.2	5.0
Sitting height	2.7	19.3	37.7	6.1	1.0
Fluid intelligence score	2.7	5.6	8.6	-1.6	-2.9
Ovarian Cancer	2.6	3.5	6.9	0.3	2.6
Systolic Blood Pressure	2.6	12.9	21.2	4.6	-2.1
Neuroticism	2.6	6.3	11.6	-1.0	-3.4
Number of live births	2.6	3.7	5.7	-1.3	2.4
Number of full brothers	2.6	3.3	6.6	-2.6	0.2
Hearing aid user	2.6	2.9	3.2	-1.8	-1.6
Irritability	2.6	4.3	8.3	-0.6	-2.9
Neuroticism (Nagel 2018)	2.5	5.9	10.3	-1.2	-3.2
Medication: Lansoprazole	2.5	2.9	5.6	2.4	-0.4
Chronic bronchitis/emphysema (father)	2.4	2.8	5.4	-2.3	0.4
Trunk fat-free mass	2.4	13.6	14.3	3.8	3.6
Lung cancer (father)	2.4	2.9	4.0	1.3	2.0
Trunk predicted mass	2.4	13.5	14.1	3.8	3.6
Angina (self-reported)	2.4	3.2	5.8	-2.4	0.8
Back pain experienced in last month	2.4	3.5	6.6	0.6	-2.6
Alzheimer’s Disease (in mother)	2.3	2.6	5.3	-2.3	-0.1
Qualifications: CSEs or equivalent	2.3	3.1	6.1	-0.0	2.5
Pain all over the body in last month	2.3	2.5	3.8	1.9	1.1
Medication: Ramipril	2.3	3.0	6.0	0.1	-2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.3	2.7	5.2	-0.4	-2.3
Tinnitus: Yes, now most or all of the time	2.3	2.7	4.9	-0.8	-2.2
Deep venous thrombosis (DVT) (self-reported)	2.3	3.0	4.0	1.4	2.0
Sensitivity / hurt feelings	2.2	3.7	7.1	0.7	-2.7
Diabetes (mother)	2.1	2.7	3.8	-1.3	1.9
Alcohol intake frequency.	2.1	4.8	9.5	0.4	3.1
Alcohol drinker status: Previous	2.1	2.4	4.2	2.0	0.8
Hair/balding pattern: Pattern 4	2.0	4.8	8.5	2.9	1.1
Whole body fat-free mass	2.0	11.4	11.8	3.4	3.3
Osteoarthritis (self-reported)	2.0	2.6	3.9	-2.0	-1.1
Basal metabolic rate	2.0	11.2	11.7	3.3	3.4
Major Depression (MDD)	1.9	2.3	3.3	-1.1	-1.8
Angina	1.9	2.5	4.5	-2.1	0.8
Neuroticism score	1.9	3.9	7.5	0.6	-2.7
Tense / ‘highly strung’	1.9	3.1	5.7	0.7	-2.4
Arm fat-free mass (right)	1.9	9.6	10.2	3.2	3.0
Mean time to correctly identify matches	1.9	3.6	4.1	-2.0	-1.8
Family relationship satisfaction	1.9	2.4	2.7	-1.4	-1.6
Commuting to job workplace: Car/motor vehicle	1.9	2.2	4.2	2.1	-0.4
Mineral and other dietary supplements	1.9	2.6	5.1	2.3	0.2
Whole body water mass	1.9	10.9	11.0	3.3	3.3
Arm fat-free mass (left)	1.9	9.5	9.7	3.1	3.1
Depressed Affect (Nagel 2018)	1.8	3.7	5.4	-1.4	-2.3
Intelligence (Savage-Jansen 2018)	1.8	5.6	9.0	-1.5	-3.0
Blood Platelet Count	1.8	21.0	21.8	-4.7	-4.5
Financial difficulties in last 2 years	1.8	2.4	4.8	-2.2	0.2
Mouth/teeth dental problems	1.8	2.8	4.2	-2.1	-1.2
Depression (self-reported)	1.8	2.2	3.9	0.7	-2.0
Number of children fathered	1.8	2.1	3.5	1.9	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	1.8	3.7	6.5	1.0	2.5
Medication: Atorvastatin	1.8	2.3	3.3	1.8	-1.1
HDL Cholesterol	1.7	2.8	5.5	0.2	-2.3
Hair/balding pattern: Pattern 2	1.7	2.2	3.8	-0.8	-1.9
Arm predicted mass (right)	1.7	8.6	9.5	3.1	2.8
Illnesses of father: Heart disease	1.7	2.3	2.8	-1.4	-1.7
Bipolar Disorder (2018)	1.6	2.6	5.1	-2.3	-0.1
Reaction Time	1.6	3.1	4.8	-2.2	-1.2
Smoking Status	1.6	3.9	7.3	-2.7	0.6
Ever had hysterectomy (womb removed)	1.6	1.8	2.9	-0.9	1.7
Hypothyroidism/myxoedema (self-reported)	1.6	3.2	3.6	-1.9	-1.7
Breast cancer (self-reported)	1.6	1.9	2.7	1.6	1.1
Medication: Bendroflumethiazide	1.6	2.4	3.6	1.1	-1.9
Arm predicted mass (left)	1.6	8.1	8.6	2.8	2.9
HbA1C	1.5	1.6	3.2	0.2	1.8
Diverticular disease/diverticulitis (self-reported)	1.5	1.7	2.1	1.4	1.2
Weight	1.5	7.4	9.6	2.3	3.1
Alcohol intake versus 10 years previously	1.5	2.3	3.0	-1.7	1.2
Blood clot in the leg (DVT)	1.5	2.0	2.9	1.0	1.7
Ever had bowel cancer screening	1.5	1.7	2.9	-1.7	-0.8
Miserableness	1.5	2.6	5.0	-0.4	-2.2
Age at First Birth	1.4	2.0	2.6	-1.2	-1.6
Body Mass Index (BMI) (2010)	1.4	1.9	3.2	-1.8	-0.8
LDL Cholesterol	1.4	2.1	3.7	-0.7	-1.9
Leg fat-free mass (left)	1.4	7.5	8.0	2.6	2.8
Multivitamins +/- minerals	1.4	1.8	3.0	-1.7	-0.8
Leg predicted mass (left)	1.4	7.6	8.1	2.7	2.9
Hair/balding pattern: Pattern 3	1.4	2.0	3.4	-0.8	-1.9
Prospective memory result	1.4	1.8	3.2	0.6	1.8
Loud music exposure frequency	1.4	1.5	1.8	1.1	1.4
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	2.9	1.7	0.8
Supplements: Fish oil (including cod liver oil)	1.4	1.9	3.3	-1.8	-0.7
High cholesterol (Self-reported)	1.4	2.4	4.1	-2.0	-0.9
Pack years adult smoking proportion	1.3	2.0	3.4	-1.8	-0.7
Mouth/teeth dental problems: Dentures	1.3	2.2	3.5	1.9	0.9
Worry too long after embarrassment	1.3	2.2	3.8	-0.7	-2.0
Smoking status: Previous	1.3	2.0	3.7	-1.9	-0.6
Mood swings	1.3	2.4	4.6	0.3	-2.1
Wears glasses or contact lenses	1.3	1.5	2.4	-1.5	-0.8
Average weekly beer plus cider intake	1.3	1.9	2.9	1.0	-1.7
Rheumatoid Arthritis	1.2	1.7	1.8	1.4	1.3
Hypothyroidism (self reported)	1.2	2.9	5.0	-2.2	-0.8
Lung FVC	1.2	5.9	7.7	-2.0	-2.8
Systolic blood pressure, automated reading	1.2	3.5	7.0	2.6	-0.3
Relative age voice broke	1.2	1.9	3.2	1.8	0.7
High blood pressure (mother)	1.2	1.7	2.5	1.6	0.9
Waist circumference	1.2	4.2	8.1	0.6	2.8
Hearing difficulty/problems with background noise	1.2	1.9	2.4	-1.5	-1.1
Exposure to tobacco smoke at home	1.2	1.3	1.3	1.1	1.2
Emphysema/chronic bronchitis	1.2	1.3	2.0	-1.4	0.9
Leg pain on walking	1.2	1.5	3.0	-1.7	-0.1
Hair Pigment	1.1	30.7	43.4	-6.6	-4.2
Age when periods started (menarche)	1.1	2.6	3.0	1.7	1.5
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	1.7	1.3	1.0
Trunk fat mass	1.1	4.7	7.1	1.5	2.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	2.1	-1.5	-0.8
Wheeze or whistling in the chest in last year	1.1	2.0	2.1	-1.5	-1.4
Leg fat-free mass (right)	1.1	5.9	6.0	2.5	2.4
Leg predicted mass (right)	1.1	6.1	6.6	2.6	2.4
Breast Cancer	1.0	2.3	3.3	1.1	1.8
Primary Biliary Cirrhosis	1.0	1.4	2.6	-1.6	0.4
Lung FEV1/FVC ratio	1.0	5.1	10.0	0.3	3.2
Frequency of depressed mood in last 2 weeks	1.0	1.4	2.1	-1.4	-0.8
Medication: Co-codamol	1.0	1.2	2.2	0.4	1.5
Average weekly fortified wine intake	1.0	1.1	2.0	-1.4	-0.6
Heart attack	1.0	1.2	2.4	-0.1	1.6
Happiness	1.0	1.2	1.3	-1.1	-1.1
Birth weight	1.0	2.2	2.9	-1.7	1.2
Eye problems/disorders: Cataract	1.0	1.2	2.3	1.5	0.0
Heart attack/myocardial infarction (self-reported)	1.0	1.2	2.5	-0.2	1.6
Bipolar Disorder or Schizophrenia	0.9	2.1	4.2	-2.1	-0.2
Irritable Bowel Disease (IBD)	0.9	2.2	4.1	2.0	0.4
Neuroticism (2016)	0.9	1.4	1.8	-1.0	-1.3
Ulcerative Colitis	0.9	1.3	2.2	0.6	-1.5
Medication for hormone replacement therapy	0.9	1.0	1.2	1.1	-0.9
Hand grip strength (right)	0.9	2.4	4.0	0.9	-2.0
Medication: Levothyroxine sodium	0.9	1.6	1.8	-1.3	-1.1
Had menopause	0.9	1.2	2.3	-0.2	1.5
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.0	-1.4	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	1.6	-1.2	-1.3
Whole body fat mass	0.9	3.7	6.2	1.1	2.5
Pack years of smoking	0.9	1.4	2.6	-1.6	-0.4
Ulcerative Colitis (UC)	0.8	1.6	3.1	1.8	-0.2
Coronary Artery Disease (CAD)	0.8	0.9	1.2	-0.8	1.1
Mean Putamen Volume	0.8	1.0	1.4	1.2	-0.7
Vitamin and mineral supplements	0.8	1.1	1.2	1.1	1.0
Severe depression (siblings)	0.8	0.9	1.7	-1.3	-0.3
Current tobacco smoking	0.8	1.3	1.7	-1.3	0.9
Fed-up feelings	0.8	1.5	2.8	0.5	-1.7
Past tobacco smoking	0.8	1.4	2.7	1.6	0.4
Time employed in main current job	0.8	0.9	1.3	1.1	0.7
Breastfed as a baby	0.8	1.0	1.8	-0.5	1.4
Medication: Blood pressure	0.8	1.5	2.2	0.9	-1.5
Handedness (chirality/laterality): Left-handed	0.8	1.0	1.1	0.9	1.1
Friendships satisfaction	0.8	1.0	1.1	1.1	-0.9
Commuting to job workplace: Walk	0.8	0.9	1.7	-0.2	1.3
Illnesses of father: None of the above (group 1)	0.8	1.0	1.1	0.9	1.0
Mother’s age at death	0.8	1.0	1.8	-1.3	-0.4
Myopia	0.8	1.2	2.2	-0.3	-1.5
Alzheimer’s Disease (in father)	0.7	0.7	1.4	-1.2	-0.3
Crohns Disease (2017)	0.7	1.6	2.2	1.0	1.5
Crohns Disease (2012)	0.7	1.1	1.7	0.6	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.2	2.3	-0.2	-1.5
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	1.5	-1.2	0.5
Illnesses of mother	0.7	0.8	1.1	-0.8	-1.0
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.2	-0.6	1.1
Guilty feelings	0.7	1.0	1.9	-0.3	-1.4
Diastolic blood pressure, automated reading	0.7	2.1	3.4	1.9	-0.9
Commuting to job workplace: Cycle	0.7	0.8	1.3	-0.6	-1.1
Hand grip strength (left)	0.6	1.5	2.9	-0.3	-1.7
Noisy workplace	0.6	0.7	1.4	0.2	1.2
Medication: Cholesterol lowering	0.6	0.9	1.5	-1.2	-0.5
Arm fat mass (right)	0.6	2.4	4.1	0.8	2.0
High blood pressure (siblings)	0.6	0.9	1.8	1.4	0.1
Shortness of breath walking on level ground	0.6	0.7	1.3	-1.1	-0.4
Suffer from ‘nerves’	0.6	1.0	1.1	0.9	-1.1
Supplements: Vitamin C	0.6	0.8	1.4	1.2	0.3
Medication for cholesterol	0.6	0.9	1.7	0.0	1.3
Smoking status: Current	0.6	1.0	1.5	-1.2	0.7
Commuting to job workplace: Public transport	0.6	0.7	0.8	-0.8	0.9
Medication: Blood pressure	0.6	1.1	2.0	0.5	-1.4
Ever smoked	0.6	1.1	2.0	-1.4	-0.4
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.1	1.0	-0.6
Age started oral contraceptive pill	0.6	0.7	1.5	0.2	1.2
Unable to work because of sickness or disability	0.6	0.8	1.0	0.8	1.0
Schizophrenia vs Biploar Disorder	0.5	0.7	1.1	0.6	-1.0
Worry (Nagel 2018)	0.5	1.0	1.9	0.3	-1.4
Bipolar Disorder (2011)	0.5	0.4	0.9	-0.9	0.0
Blood White Count	0.5	3.4	5.0	-1.3	2.2
Tanning	0.5	6.1	9.9	3.1	1.5
Average weekly spirits intake	0.5	0.7	1.1	1.0	0.5
Medication: Metformin	0.5	0.7	1.4	-1.2	0.2
Impedance of leg (right)	0.5	2.3	4.1	0.7	2.0
Trunk fat percentage	0.5	2.1	3.6	0.8	1.9
Stomach or abdominal pain in last month	0.5	0.7	1.0	0.5	-1.0
Illnesses of siblings	0.5	0.7	1.1	-0.4	-1.1
Medication: Amlodipine	0.5	0.7	0.7	0.8	-0.8
Chest pain or discomfort	0.5	0.7	1.0	-1.0	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.1	0.3	-1.0
Osteoporosis (self-reported)	0.5	0.7	1.1	-0.5	1.1
Arm fat mass (left)	0.5	2.0	3.1	0.9	1.8
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.0	-1.0	0.4
Ever depressed for a whole week	0.5	0.6	1.0	-1.0	0.4
Heart disease (siblings)	0.5	0.6	0.8	-0.9	-0.7
Schizophrenia (2014)	0.4	0.8	1.7	-0.0	-1.3
Relative age of first facial hair	0.4	0.9	0.9	0.9	0.9
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.9	-0.9	-0.4
Supplements: Zinc	0.4	0.4	0.8	-0.2	-0.9
Taking other prescription medications	0.4	0.7	1.2	1.1	0.4
High blood pressure	0.4	1.0	1.5	1.2	-0.8
Nervous feelings	0.4	0.8	1.1	-1.0	-0.7
Diabetes (self-reported)	0.4	0.6	1.1	-0.3	-1.0
Impedance of arm (right)	0.4	2.1	4.2	-0.1	2.0
Falls in the last year	0.4	0.5	0.8	0.4	0.9
Ever highly irritable/argumentative for 2 days	0.4	0.5	0.7	-0.8	-0.6
Medication: Paracetamol	0.4	0.7	1.1	1.1	0.5
Glaucoma (self-reported)	0.4	0.5	1.0	-1.0	-0.0
Comparative body size at age 10	0.4	1.1	1.6	-0.8	1.3
Eye problems/disorders: None of the above	0.4	0.5	1.0	-0.1	1.0
Leg fat mass (right)	0.4	1.7	2.9	0.7	1.7
Pulse rate, automated reading	0.4	1.3	2.0	-1.4	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	0.6	0.8	0.4
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.3	-0.1	1.1
Medication: Gliclazide	0.4	0.4	0.5	0.5	-0.7
Financial situation satisfaction	0.4	0.6	0.9	-0.5	-0.9
Medication: Paracetamol	0.4	0.6	0.8	0.6	0.9
Medication: Lisinopril	0.4	0.5	0.8	0.9	0.5
Supplements: Calcium	0.4	0.4	0.7	0.8	0.4
Leg fat mass (left)	0.4	1.5	2.7	0.6	1.6
Allergy or Eczema	0.3	0.8	1.5	-1.2	-0.3
Cardiovascular Disease	0.3	1.0	1.5	-0.7	-1.2
Chronotype (morning person)	0.3	0.6	0.9	0.6	1.0
Ever used hormone-replacement therapy (HRT)	0.3	0.4	0.7	0.2	-0.8
Impedance of leg (left)	0.3	1.2	2.3	0.4	1.5
Worrier / anxious feelings	0.3	0.5	0.6	0.7	-0.8
Pulse wave Arterial Stiffness index	0.3	0.4	0.6	0.4	0.8
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	0.5	-0.6	-0.7
Medication: Ventolin 100micrograms inhaler	0.3	0.3	0.5	-0.7	0.4
Body fat percentage	0.3	1.1	2.2	0.3	1.5
Medication for pain relief, constipation, heartburn	0.3	0.6	1.1	-0.1	-1.1
Heart disease (mother)	0.3	0.3	0.6	0.8	0.2
Overall health rating	0.3	0.6	1.3	0.1	-1.1
Medication: Aspirin	0.3	0.4	0.8	-0.9	-0.1
Hypertension (Self-reported)	0.3	0.9	1.3	1.1	-0.7
Average weekly red wine intake	0.3	0.5	1.0	0.1	-1.0
Loneliness, isolation	0.3	0.5	0.6	-0.6	-0.8
Illnesses of father: High blood pressure	0.3	0.3	0.5	-0.7	-0.4
Number of operations (self-reported)	0.3	0.4	0.8	-0.1	0.9
Schizophrenia (2018)	0.2	0.3	0.5	-0.7	-0.4
Townsend deprivation index at recruitment	0.2	0.2	0.3	-0.4	0.6
Serious illness, injury or assault to yourself	0.2	0.2	0.3	-0.3	0.5
Alcohol usually taken with meals	0.2	0.3	0.6	0.0	0.8
Forced vital capacity (FVC)	0.2	0.7	1.4	1.2	0.1
Arm fat percentage (right)	0.2	0.8	1.5	-0.4	1.2
Father’s age at death	0.2	0.3	0.7	0.1	0.8
Pulse rate	0.2	0.4	0.7	-0.8	-0.2
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.1	-0.1	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	-0.2	0.7
Asthma	0.2	0.4	0.7	0.3	-0.8
Impedance of arm (left)	0.2	0.8	1.5	0.3	1.2
Peak expiratory flow (PEF)	0.2	0.5	0.8	0.4	0.9
Health satisfaction	0.2	0.3	0.5	-0.2	-0.7
Neck or shoulder pain in last month	0.2	0.3	0.4	-0.6	-0.4
Migraine (self-reported)	0.2	0.2	0.2	-0.4	-0.5
Medication: Seretide 50 evohaler	0.2	0.2	0.4	0.6	-0.1
Number of full sisters	0.2	0.2	0.4	0.1	0.7
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.2	0.5	-0.5
Knee pain experienced in last month	0.2	0.3	0.5	-0.7	0.3
Illnesses of siblings: Diabetes	0.2	0.2	0.4	-0.7	0.2
Long-standing illness, disability or infirmity	0.2	0.4	0.5	-0.5	0.7
Qualifications: nursing, teaching	0.2	0.2	0.5	0.0	-0.7
Medication: Aspirin	0.2	0.2	0.4	-0.7	-0.2
Number of self-reported non-cancer illnesses	0.2	0.4	0.5	-0.7	-0.5
Risk taking	0.2	0.3	0.5	-0.7	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.5	0.7	-0.1
Impedance of whole body	0.2	0.9	1.5	0.5	1.2
Prostate Cancer	0.1	0.1	0.1	0.3	0.3
Triglycerides	0.1	0.2	0.3	0.6	0.4
BMI	0.1	0.7	0.9	-1.0	-0.8
Respiratory disease	0.1	0.3	0.4	-0.3	-0.6
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.3	0.6	-0.0
Hearing difficulty/problems: Yes	0.1	0.1	0.2	-0.2	-0.4
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.4	-0.6	-0.1
Medication: Atenolol	0.1	0.1	0.1	-0.3	0.3
Number of incorrect matches in round	0.1	0.2	0.4	-0.3	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.4	0.3	0.6
Allergy	0.1	0.2	0.4	0.6	0.3
Hip circumference	0.1	0.5	0.5	0.7	0.7
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.5	0.7	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.7	0.2	0.9
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.4	-0.1	0.7
Gout (self-reported)	0.1	0.2	0.3	0.3	0.5
Forced vital capacity (FVC), Best measure	0.1	0.5	0.8	0.6	0.9
Leg fat percentage (right)	0.1	0.5	0.9	-0.3	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.1	0.2	0.4
Medication: Allopurinol	0.1	0.2	0.2	0.4	-0.4
Medication: Omeprazole	0.1	0.2	0.3	0.3	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	0.1	0.4
Arm fat percentage (left)	0.1	0.5	0.9	-0.3	0.9
Diabetes diagnosed by doctor	0.1	0.1	0.2	-0.5	0.1
Asthma (self-reported)	0.1	0.3	0.6	0.1	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.3	0.4	-0.5
Average weekly champagne plus white wine intake	0.1	0.1	0.2	0.1	-0.5
Eye problems/disorders: Glaucoma	0.1	0.1	0.2	-0.4	-0.0
Leg fat percentage (left)	0.1	0.3	0.6	-0.4	0.7
Blood Eosinophil Count	0.0	0.0	0.0	-0.0	-0.1
Heel T-Score	0.0	0.2	0.4	-0.1	-0.7
Number of treatments/medications taken	0.0	0.0	0.1	-0.1	0.3
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.1	-0.1	-0.3
Diabetes (father)	0.0	0.0	0.1	-0.0	0.3
Maternal smoking around birth	0.0	0.0	0.0	-0.2	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.0	0.0	0.0	-0.1
Body mass index (BMI)	0.0	0.0	0.0	-0.1	0.2
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.1	-0.3	-0.1
Pulse wave reflection index	0.0	0.0	0.1	0.0	-0.3
Headache pain in last month	0.0	0.1	0.1	-0.0	-0.4
Pulse wave peak to peak time	0.0	0.0	0.1	-0.0	-0.3
Medication: Ibuprofen	0.0	0.1	0.1	-0.2	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.1	0.2	0.2
Ever taken oral contraceptive pill	0.0	0.0	0.1	-0.0	-0.3
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.1	0.3	0.3
Pain experienced in last month	0.0	0.0	0.0	-0.1	0.1

Hub : Genes

FAM106A

Models

Trait associations