Hub : Genes

SHMT1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2160 0.0560 7.3e-14 0.143 0.150 0.168 0.156 0.163 4.7e-17 8.1e-18 5.4e-20 1.4e-18 2.3e-19
2 GTEx Adipose Subcutaneous 0.2000 0.0810 1.1e-04 0.069 NA 0.033 NA 0.045 2.7e-06 NA 9.8e-04 NA 1.4e-04
3 GTEx Adrenal Gland 0.5704 0.1004 2.4e-09 0.249 NA 0.334 NA 0.126 2.0e-09 NA 9.9e-13 NA 2.8e-05
4 GTEx Artery Aorta 0.3530 0.0780 4.2e-12 0.205 NA 0.311 NA 0.297 1.7e-11 NA 1.3e-17 NA 9.0e-17
5 GTEx Artery Tibial 0.4859 0.0576 0.0e+00 0.292 NA 0.429 NA 0.445 3.6e-23 NA 2.3e-36 NA 4.0e-38
6 GTEx Cells EBV-transformed lymphocytes 0.3770 0.1020 2.2e-07 0.259 NA 0.187 NA 0.237 5.2e-09 NA 1.0e-06 NA 2.7e-08
7 GTEx Cells Transformed fibroblasts 0.4190 0.0730 0.0e+00 0.274 NA 0.389 NA 0.394 1.2e-20 NA 8.7e-31 NA 2.7e-31
8 GTEx Colon Transverse 0.0830 0.0510 4.8e-03 0.012 NA 0.034 NA 0.024 8.4e-02 NA 9.6e-03 NA 2.5e-02
9 GTEx Esophagus Gastroesophageal Junction 0.1490 0.0730 2.6e-03 0.005 NA 0.001 NA 0.003 2.1e-01 NA 3.0e-01 NA 2.5e-01
10 GTEx Esophagus Mucosa 0.2550 0.0910 1.1e-05 0.033 NA 0.056 NA 0.048 2.7e-03 NA 1.2e-04 NA 3.7e-04
11 GTEx Esophagus Muscularis 0.2770 0.0620 5.1e-15 0.209 NA 0.263 NA 0.340 8.1e-13 NA 3.5e-16 NA 2.3e-21
12 GTEx Heart Atrial Appendage 0.1220 0.0580 7.3e-03 0.059 NA 0.053 NA 0.060 1.2e-03 NA 2.1e-03 NA 1.1e-03
13 GTEx Heart Left Ventricle 0.2734 0.0628 5.7e-11 0.202 NA 0.272 NA 0.189 5.5e-11 NA 8.4e-15 NA 2.4e-10
14 GTEx Liver 0.3570 0.1020 3.3e-04 0.221 NA 0.019 NA 0.197 8.3e-07 NA 9.4e-02 NA 3.5e-06
15 GTEx Lung 0.1487 0.0445 1.1e-08 0.127 NA 0.156 NA 0.161 5.7e-10 NA 5.2e-12 NA 2.4e-12
16 GTEx Muscle Skeletal 0.1623 0.0468 2.8e-09 0.084 NA 0.113 NA 0.130 1.3e-08 NA 3.4e-11 NA 1.0e-12
17 GTEx Nerve Tibial 0.3004 0.0667 5.6e-17 0.197 NA 0.282 NA 0.292 6.0e-14 NA 3.4e-20 NA 5.5e-21
18 GTEx Prostate 0.1850 0.1010 5.0e-03 0.185 NA 0.057 NA 0.153 2.1e-05 NA 1.5e-02 NA 1.1e-04
19 GTEx Spleen 0.5380 0.1060 7.8e-05 0.300 NA 0.235 NA 0.240 2.0e-08 NA 1.0e-06 NA 7.7e-07
20 GTEx Stomach 0.2130 0.0730 1.1e-05 0.052 NA 0.078 NA 0.055 1.6e-03 NA 1.3e-04 NA 1.3e-03
21 GTEx Testis 0.2780 0.1030 6.5e-03 0.048 NA 0.117 NA 0.078 3.5e-03 NA 7.6e-06 NA 2.5e-04
22 GTEx Thyroid 0.1410 0.0460 1.6e-07 0.143 NA 0.141 NA 0.150 4.4e-11 NA 6.4e-11 NA 1.4e-11
23 GTEx Vagina 0.3760 0.1480 2.6e-03 0.025 NA -0.013 NA -0.010 9.1e-02 NA 9.9e-01 NA 6.6e-01
24 GTEx Whole Blood 0.2830 0.0590 3.2e-15 0.112 NA 0.204 NA 0.206 1.6e-10 NA 1.3e-18 NA 9.8e-19
25 METSIM Adipose 0.1193 0.0528 3.7e-04 0.016 0.026 0.016 0.027 0.023 1.6e-03 8.2e-05 1.7e-03 5.4e-05 1.9e-04
26 NTR Blood 0.0271 0.0130 5.2e-04 0.014 0.012 0.011 0.012 0.011 2.3e-05 7.4e-05 1.0e-04 4.7e-05 1.0e-04
27 ROSMAP Brain Pre-frontal Cortex 0.2629 0.0700 2.0e-10 0.102 0.080 0.092 0.067 0.041 5.1e-13 1.8e-10 6.8e-12 5.4e-09 4.8e-06
28 YFS Blood 0.4639 0.0556 0.0e+00 0.275 0.392 0.399 0.406 0.390 2.2e-90 1.0e-138 7.6e-142 7.3e-145 6.8e-138
29 TCGA Bladder Urothelial Carcinoma 0.0650 0.0320 3.1e-05 0.072 0.051 0.055 NA 0.060 1.1e-06 3.5e-05 2.0e-05 NA 8.3e-06
30 TCGA Breast Invasive Carcinoma 0.0577 0.0247 2.9e-12 0.053 0.052 0.051 NA 0.049 3.9e-11 8.2e-11 9.9e-11 NA 2.8e-10
31 TCGA Cervical Squamous Cell Carcinoma 0.1070 0.0810 3.7e-03 0.049 0.041 0.037 NA 0.042 1.9e-03 4.4e-03 6.3e-03 NA 4.0e-03
32 TCGA Colon Adenocarcinoma 0.0810 0.0400 3.2e-05 0.059 0.062 0.063 NA 0.061 2.5e-04 1.9e-04 1.6e-04 NA 2.1e-04
33 TCGA Head and Neck Squamous Cell Carcinoma 0.1186 0.0521 3.6e-10 0.064 0.072 0.056 NA 0.068 9.5e-08 1.6e-08 6.0e-07 NA 4.3e-08
34 TCGA Kidney Renal Papillary Cell Carcinoma 0.0540 0.0340 9.6e-03 0.023 0.010 0.023 NA 0.003 1.7e-02 7.8e-02 1.7e-02 NA 2.2e-01
35 TCGA Brain Lower Grade Glioma 0.0626 0.0326 1.6e-05 0.024 0.044 0.034 NA 0.029 8.5e-04 9.4e-06 7.7e-05 NA 2.9e-04
36 TCGA Liver Hepatocellular Carcinoma 0.1960 0.0830 1.1e-07 0.183 0.138 0.156 NA 0.165 5.1e-09 5.2e-07 8.4e-08 NA 3.2e-08
37 TCGA Lung Adenocarcinoma 0.0450 0.0234 3.1e-05 0.046 0.035 0.024 NA 0.042 3.7e-06 5.0e-05 6.7e-04 NA 9.2e-06
38 TCGA Lung Squamous Cell Carcinoma 0.0676 0.0330 9.6e-08 0.031 0.049 0.049 NA 0.042 1.8e-04 2.5e-06 2.5e-06 NA 1.5e-05
39 TCGA Pancreatic Adenocarcinoma 0.1170 0.0640 8.7e-04 0.077 0.055 0.067 NA 0.061 3.9e-04 2.5e-03 8.8e-04 NA 1.4e-03
40 TCGA Pheochromocytoma and Paraganglioma 0.1900 0.0800 7.1e-06 0.126 0.113 0.082 NA 0.108 1.1e-05 3.1e-05 3.6e-04 NA 4.5e-05
41 TCGA Prostate Adenocarcinoma 0.0844 0.0469 1.2e-04 0.033 0.021 0.008 NA 0.022 2.0e-04 2.5e-03 3.9e-02 NA 1.9e-03
42 TCGA Rectum Adenocarcinoma 0.4880 0.2320 2.6e-03 0.157 0.099 0.085 NA 0.106 1.6e-04 2.6e-03 5.1e-03 NA 1.9e-03
43 TCGA Soft Tissue Sarcoma 0.0740 0.0380 3.6e-04 0.063 0.047 0.037 NA 0.051 1.3e-04 8.5e-04 2.9e-03 NA 5.5e-04
44 TCGA Stomach Adenocarcinoma 0.1730 0.0830 1.8e-06 0.096 0.051 0.077 NA 0.085 1.9e-07 1.4e-04 3.0e-06 NA 1.0e-06
45 TCGA Thyroid Carcinoma 0.0470 0.0350 1.7e-03 0.031 0.019 0.011 NA 0.027 5.2e-04 5.0e-03 2.5e-02 NA 1.1e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45
Bipolar Disorder (2018) 0.4 0.6 5.7 0.7 0.6 0.6 0.7 0.4 0.9 0.5 -0.4 2.4 -0.3 0.5 0.6 -0.5 -1.4 0.2 0.4 0.5 -0.1 -1.2 0.0 -0.2 0.2 -2.0 -0.6 0.2 -0.2 1.1 0.4 1.0 0.4 0.6 0.4 0.8 0.6 -0.5 0.7 0.3 0.5 0.9 1.3 0.5 0.4 1.0 1.0 0.4
Bipolar Disorder or Schizophrenia 0.4 1.0 15.9 0.6 0.8 -0.7 0.5 -0.2 0.2 -0.1 -4.0 1.3 -1.4 -0.1 0.3 -0.9 -1.6 -1.2 -0.1 -0.6 -1.1 -1.5 -0.4 -0.1 -0.9 -1.9 -1.2 -0.9 0.0 1.3 -0.3 1.0 0.3 -0.1 -0.7 0.8 -0.3 -0.8 0.5 0.1 0.0 0.2 1.4 -0.5 0.0 0.9 0.8 -0.7
Depressed Affect (Nagel 2018) 2.9 6.1 15.1 3.2 1.4 1.9 2.6 2.5 2.6 3.0 -0.3 3.9 1.2 2.5 2.1 1.4 -3.0 2.4 2.4 2.9 1.6 -3.0 2.2 -0.3 3.1 -3.5 -0.7 -0.7 1.9 1.0 1.6 2.1 2.1 3.2 3.4 2.6 3.8 0.2 2.1 1.3 2.4 3.1 2.8 3.3 1.1 2.4 2.8 3.9
Depression (Nagel 2018) 3.3 5.0 18.6 2.6 1.3 2.2 2.6 2.1 2.4 2.3 -1.2 4.3 1.1 2.2 2.0 1.0 -3.3 2.0 2.2 2.7 1.4 -3.3 1.8 -1.2 2.3 -3.5 -0.9 -0.3 1.5 1.2 1.2 2.2 2.0 2.5 2.6 2.6 2.8 -0.0 1.9 1.5 2.1 2.6 3.1 2.5 1.0 2.3 2.6 2.9
Intelligence (Savage-Jansen 2018) 1.6 4.9 13.6 2.7 1.3 2.0 2.5 2.7 2.4 2.5 3.6 3.7 2.3 2.6 2.3 0.6 -1.5 2.4 2.4 2.8 2.8 -1.3 2.0 -1.2 2.3 -2.9 0.8 1.7 1.5 1.6 1.6 1.5 2.2 2.4 2.4 2.3 2.2 0.9 1.7 2.0 2.4 2.3 2.4 2.4 2.2 1.7 1.9 2.6
Neuroticism (Nagel 2018) 4.7 10.9 22.1 3.9 3.8 3.2 3.8 3.1 4.4 3.7 -1.1 4.7 1.2 3.2 3.4 2.7 -1.2 3.3 3.5 3.7 1.2 -1.1 3.1 -1.9 2.8 -4.2 1.5 1.6 3.3 1.6 2.9 4.4 3.8 3.7 3.6 4.2 2.5 2.4 4.2 3.0 3.5 4.5 4.4 2.7 2.4 4.5 4.7 3.4
Schizophrenia (2018) 0.5 1.1 23.0 0.2 0.5 -1.3 0.1 -0.6 -0.6 -0.6 -4.8 -0.3 -1.6 -0.6 -0.1 -0.7 -0.9 -1.7 -0.4 -1.1 -1.2 -1.0 -0.5 -0.1 -1.3 -0.8 -1.1 -1.3 0.1 0.8 -0.7 0.5 0.1 -0.7 -1.2 0.4 -0.9 -0.6 0.1 0.1 -0.4 -0.4 0.7 -1.1 -0.3 0.4 0.2 -1.3
Schizophrenia vs Biploar Disorder 0.8 1.0 16.1 -0.0 0.6 -0.3 0.8 0.5 -0.3 0.3 -4.0 -1.9 -2.3 0.3 0.4 0.5 -0.8 -0.4 0.5 -0.1 1.6 -1.1 -0.2 -1.1 0.1 1.3 -0.6 -1.0 2.1 1.5 0.3 0.5 0.6 0.4 0.2 0.8 -0.0 0.0 0.4 0.5 0.4 0.1 0.9 0.3 -0.2 0.5 0.5 0.2
Worry (Nagel 2018) 1.7 3.5 10.0 1.7 3.0 1.9 1.7 0.9 2.8 1.6 -1.9 2.9 0.1 1.2 1.7 1.9 0.6 1.7 1.6 1.6 -0.8 0.7 1.5 -1.5 0.7 -2.4 1.5 1.7 1.9 0.3 1.9 3.2 2.1 1.6 1.4 2.3 -0.1 2.0 2.9 1.6 1.6 2.6 2.5 0.5 1.0 3.1 3.0 0.9
Alzheimer’s Disease (in mother) 1.1 1.3 10.9 -0.7 -0.6 -0.6 -0.1 -0.3 0.1 -0.0 3.3 1.6 2.1 -0.2 -0.6 -1.4 -2.6 -0.3 -0.5 0.2 -0.6 -2.5 -0.5 -1.6 0.2 -1.1 -2.2 0.0 -1.9 -0.4 -0.8 -0.6 -0.5 0.1 -0.0 0.0 1.1 -1.8 -0.7 -0.9 -0.5 -0.6 0.1 0.6 -1.5 -0.5 -0.4 0.5
Alzheimer’s Disease (in father) 0.2 0.2 1.2 -0.3 0.2 0.1 0.2 -0.3 0.2 -0.1 1.0 0.5 1.1 -0.3 -0.3 -0.4 -0.9 -0.1 -0.2 -0.0 -0.6 -0.8 -0.2 -0.9 -0.1 0.1 -0.5 0.3 -1.0 -0.3 -0.3 0.1 -0.1 -0.1 0.1 0.2 -0.3 -0.3 -0.1 -0.4 -0.3 -0.3 0.3 -0.0 -1.1 0.1 0.2 0.1
Alzheimer’s Disease (including proxy) 0.8 1.2 11.3 0.0 -0.2 0.2 0.5 0.1 0.4 0.3 3.4 2.1 2.2 0.1 -0.3 -0.8 -2.6 0.3 0.0 0.5 -0.3 -2.5 0.2 -1.5 0.7 -0.8 -1.7 0.5 -1.7 -0.6 -0.7 -0.0 -0.0 0.6 0.7 0.6 1.1 -1.2 -0.1 -0.8 -0.1 0.0 0.7 0.9 -1.5 0.1 0.3 1.1
Crohns Disease (2017) 0.3 0.6 4.8 -0.3 -0.0 2.2 0.0 -0.1 0.3 -0.0 -0.2 1.5 -1.7 -0.1 -0.2 1.2 1.3 1.0 -0.4 0.2 0.8 1.4 0.2 1.8 0.2 -0.5 1.1 0.6 0.7 -0.3 0.1 -0.1 -0.3 -0.1 0.5 -0.5 -0.1 0.9 0.2 -0.3 -0.1 0.4 -0.7 -0.2 0.2 -0.0 0.1 0.3
Irritable Bowel Disease (IBD) 0.9 2.2 11.7 0.2 1.7 2.8 0.5 0.5 1.2 0.5 -0.4 0.8 -0.5 0.6 1.0 2.3 3.3 1.8 0.7 0.4 0.2 3.4 0.7 0.3 0.2 0.4 3.3 2.5 1.9 0.6 1.3 1.5 1.1 0.3 0.8 0.7 -1.3 3.0 1.7 1.2 1.0 1.4 0.3 -0.5 1.4 1.4 1.4 0.1
Ulcerative Colitis (UC) 1.0 1.9 10.6 0.0 1.8 1.7 0.1 0.3 0.8 0.2 -0.3 -0.9 -0.1 0.3 1.0 1.4 3.2 0.9 0.7 -0.2 -0.7 3.3 0.3 -0.9 -0.4 1.4 3.0 2.4 1.6 1.0 1.2 1.5 1.1 -0.0 0.1 0.8 -2.1 2.8 1.6 1.4 0.8 0.9 0.5 -1.0 1.3 1.4 1.2 -0.6
Major Depression (MDD) 5.4 6.6 10.2 2.7 2.7 3.2 2.7 2.7 3.1 2.9 0.4 2.6 2.2 2.8 2.9 2.5 0.8 2.8 2.9 3.1 1.5 0.6 2.3 -1.1 2.5 -1.6 2.3 1.4 2.9 1.4 3.0 3.0 3.0 3.0 2.9 3.0 1.7 2.8 3.0 2.7 2.9 3.2 2.7 2.3 2.4 3.1 3.1 2.6
Reaction Time 0.3 0.5 8.0 0.4 0.4 -1.5 0.9 0.4 -0.0 0.2 -2.8 -0.6 0.3 0.4 0.5 -0.1 -0.7 -0.6 0.4 0.2 0.1 -0.9 -0.3 -1.6 -0.4 -0.4 -0.7 0.8 -0.6 1.1 0.3 0.3 0.5 -0.0 -0.7 0.7 -0.4 -0.4 -0.0 0.7 0.2 -0.5 0.7 -0.1 0.2 0.2 -0.0 -0.7
Verbal and Numeric Reasoning (VNR) 2.7 6.4 14.7 2.9 1.9 2.6 2.6 3.1 2.8 2.9 3.5 3.6 3.8 3.0 2.9 1.3 -0.6 3.0 2.9 3.1 1.8 -0.7 2.3 -1.4 2.5 -2.4 1.8 2.6 1.6 0.4 2.3 2.1 2.8 2.8 2.8 2.8 2.0 2.0 2.3 2.6 3.0 2.6 2.6 2.5 2.7 2.2 2.5 2.7
Breast Cancer 2.5 6.0 12.7 -2.7 -3.3 -2.0 -2.8 -2.4 -2.8 -2.7 3.3 -1.2 -1.1 -2.6 -3.0 -1.7 -0.0 -2.0 -2.8 -2.3 -0.2 0.1 -2.1 1.0 -1.8 1.6 -2.0 -0.4 -3.6 -1.6 -2.6 -3.1 -3.0 -2.7 -2.2 -3.2 -0.9 -2.4 -3.5 -2.8 -3.0 -3.4 -3.5 -1.7 -2.7 -3.1 -3.2 -1.8
Ovarian Cancer 2.2 2.9 7.7 -2.1 -1.6 -1.4 -1.6 -2.1 -1.9 -1.9 -1.6 -0.8 -1.9 -2.3 -2.3 -0.1 -0.8 -1.9 -2.2 -1.9 -0.0 -0.5 -2.0 1.1 -1.2 1.0 -2.0 -1.7 -1.4 -1.8 -2.2 -1.7 -2.0 -1.6 -1.2 -1.8 -0.1 -1.9 -1.7 -2.3 -2.3 -1.6 -2.1 -1.3 -2.8 -1.7 -1.7 -0.8
Prostate Cancer 0.3 0.4 5.2 0.1 0.6 0.5 0.5 0.4 0.3 0.3 -2.3 -0.2 -1.1 0.5 0.6 0.7 1.0 0.4 0.3 0.3 0.8 0.9 0.2 0.4 0.2 0.1 0.9 -0.2 1.0 0.5 0.6 0.6 0.5 0.3 0.2 0.4 -0.4 0.9 0.6 0.6 0.5 0.5 0.4 0.1 0.7 0.5 0.5 0.1
Age at First Birth 3.7 5.4 10.6 2.7 2.3 1.7 2.1 2.3 2.9 2.8 0.6 2.4 1.0 2.4 2.5 1.1 -1.9 1.7 2.4 2.8 2.0 -2.0 1.5 -1.1 2.4 -3.2 -0.2 0.0 2.5 1.2 2.1 2.7 2.5 3.0 2.6 2.9 3.2 0.9 2.7 2.1 2.4 3.3 3.0 2.6 1.5 2.8 2.9 2.8
Bipolar Disorder (2011) 0.4 0.4 3.3 0.7 0.1 -0.2 0.9 0.0 0.2 0.2 -0.8 1.5 -0.8 -0.1 -0.0 0.3 -1.4 -0.2 -0.1 0.1 0.0 -1.4 0.6 -0.2 0.0 -1.8 -1.0 0.1 -0.1 0.7 -0.3 0.4 0.2 0.2 0.2 0.4 0.8 -0.7 0.2 -0.1 -0.1 0.5 0.5 0.1 -0.2 0.4 0.4 0.4
Body Mass Index (BMI) (2010) 1.0 1.3 6.3 1.0 -0.9 1.5 1.2 1.4 0.2 1.3 2.1 1.5 1.5 1.3 0.6 1.1 -1.3 1.4 0.8 1.4 1.3 -1.4 1.3 0.3 2.1 0.4 -0.2 0.1 -0.4 -0.3 0.5 -0.6 0.4 1.4 1.8 0.3 2.5 -0.2 -0.5 0.2 0.9 0.3 -0.2 2.2 0.2 -0.4 -0.1 2.2
Coronary Artery Disease (CAD) 1.9 2.3 14.8 -1.5 -0.5 -1.7 -1.1 -1.7 -1.4 -1.4 -3.9 -1.6 -2.1 -1.7 -1.5 -1.0 -0.5 -2.3 -1.4 -1.7 -1.7 -0.7 -1.3 0.1 -1.5 0.4 -1.8 -1.9 -0.9 -0.1 -1.1 -1.1 -1.4 -1.3 -1.9 -1.0 -1.4 -1.7 -0.8 -1.7 -1.6 -1.6 -0.6 -1.4 -2.0 -1.2 -1.4 -1.8
Crohns Disease (2012) 0.3 0.4 4.1 -0.2 -0.3 2.0 0.3 0.1 0.2 0.3 -0.1 1.4 -0.2 0.2 -0.2 0.8 0.5 1.2 -0.1 0.5 0.3 0.6 0.3 2.0 0.8 -0.0 0.7 0.4 0.0 -1.1 0.2 -0.3 -0.3 0.4 0.9 -0.5 0.3 0.4 -0.0 -0.6 0.1 0.5 -0.4 0.6 0.0 -0.2 0.1 0.9
Mean Putamen Volume 1.3 1.5 3.6 1.3 0.6 1.8 1.5 1.3 1.1 1.5 0.2 1.3 1.5 1.2 0.9 1.7 0.1 1.8 1.3 1.6 1.3 0.2 1.8 0.9 1.8 -0.4 1.0 0.2 0.8 -0.3 1.2 0.7 0.9 1.6 1.8 0.8 1.8 0.9 1.0 0.4 1.2 1.5 0.5 1.7 0.9 0.8 1.0 1.9
Fasting Glucose 2.3 2.7 8.6 2.2 1.6 1.8 1.8 1.7 2.0 1.6 0.9 2.8 0.8 1.9 2.1 1.3 -0.8 1.4 1.8 1.5 -0.3 0.0 1.9 -2.3 0.8 -2.9 1.1 1.6 1.0 1.2 1.3 1.7 2.0 1.3 1.0 2.1 1.1 1.0 1.5 2.5 1.9 1.5 1.9 1.0 1.9 1.7 1.6 0.9
HbA1C 3.7 4.1 9.5 -2.0 -1.4 -2.2 -2.4 -2.4 -2.2 -2.5 -3.1 -1.7 -2.9 -2.4 -2.0 -1.8 -0.8 -2.6 -2.2 -2.3 -1.8 -0.4 -2.3 0.7 -2.7 0.5 -1.9 -1.9 -0.9 0.3 -2.5 -1.7 -2.0 -2.6 -2.6 -1.8 -1.8 -2.1 -1.7 -1.3 -2.3 -2.3 -1.5 -2.5 -1.9 -1.7 -2.0 -2.0
HDL Cholesterol 1.4 2.4 6.0 1.7 2.1 1.2 1.3 1.5 2.0 1.4 2.0 1.6 2.5 1.5 1.8 0.8 0.3 1.4 1.8 1.5 0.6 0.1 1.3 -2.4 0.6 -2.1 1.2 2.0 0.9 0.9 1.5 1.5 2.1 1.1 0.8 2.2 -0.2 1.7 1.9 2.1 1.6 1.5 2.1 0.4 1.5 1.5 1.4 0.5
LDL Cholesterol 1.3 2.1 7.3 1.6 2.5 0.8 1.2 1.1 2.1 1.2 0.1 1.8 0.7 1.2 1.8 -0.0 -0.4 0.5 1.5 1.0 -0.0 -0.5 0.7 -2.5 0.0 -2.4 0.5 0.8 1.4 1.3 0.9 2.2 1.9 0.9 0.4 2.3 -0.7 1.2 2.2 1.9 1.4 1.6 2.7 -0.1 1.2 2.2 2.1 0.1
Lupus 4.5 6.8 12.5 -3.2 -2.7 -2.5 -3.1 -3.1 -2.8 -2.9 -2.0 -2.3 -2.1 -3.2 -3.3 -1.0 -0.7 -2.7 -3.3 -2.9 -0.6 -0.3 -2.8 3.1 -2.0 2.5 -2.6 -3.5 -1.6 -2.3 -3.3 -2.5 -3.2 -2.5 -2.0 -3.2 0.1 -2.9 -2.6 -3.1 -3.2 -2.0 -3.3 -2.0 -2.9 -2.5 -2.6 -1.6
Neuroticism (2016) 2.3 3.3 6.0 2.0 1.8 2.2 1.9 2.0 2.2 2.2 0.4 2.0 1.2 2.1 2.0 1.4 -0.7 2.3 2.1 2.0 0.6 -0.5 1.6 -0.6 1.9 -0.9 1.3 1.0 1.6 0.8 1.6 2.1 2.0 2.2 2.4 2.2 1.5 1.4 2.1 1.6 2.2 2.4 2.2 1.9 1.6 2.2 2.4 2.4
Primary Biliary Cirrhosis 0.7 1.0 2.5 -1.3 -0.4 -1.0 -1.1 -1.3 -0.7 -1.2 -0.4 0.1 -0.8 -1.2 -1.0 -1.6 -0.6 -1.3 -1.0 -1.2 -0.8 -0.6 -1.3 -0.1 -1.5 -0.7 -1.1 0.4 -0.9 0.2 -1.2 -0.3 -0.8 -1.3 -1.4 -0.6 -1.4 -0.9 -0.7 -0.7 -1.1 -1.0 -0.2 -1.4 -1.0 -0.4 -0.5 -1.4
Rheumatoid Arthritis 0.9 1.2 11.3 -0.7 1.0 1.1 -0.2 -0.7 0.7 -0.4 -0.1 0.4 0.8 -0.4 -0.1 1.3 3.2 0.7 -0.3 -0.1 0.0 3.4 0.3 1.0 -0.7 0.7 2.5 1.5 0.1 -1.3 0.7 0.8 0.2 -0.5 -0.2 -0.2 -1.9 2.0 0.8 0.3 -0.0 0.4 -0.4 -1.2 0.4 0.7 0.5 -0.8
Schizophrenia (2014) 0.8 1.8 23.6 1.2 1.8 -0.1 1.3 0.8 0.9 0.8 -4.9 0.2 -1.9 0.8 1.3 0.4 -0.4 -0.3 1.1 0.3 0.1 -0.4 0.6 -0.3 -0.1 -1.3 0.2 -0.3 1.8 2.1 1.1 2.0 1.4 0.7 0.1 1.7 -0.5 0.7 1.6 1.1 1.1 1.1 2.1 0.1 1.0 1.9 1.7 -0.2
Triglycerides 1.6 2.6 6.2 -1.1 -1.4 -2.4 -1.7 -1.4 -1.8 -1.9 -1.7 -1.9 -2.5 -1.4 -1.2 -1.6 -0.2 -2.3 -1.6 -1.9 -0.8 -0.2 -1.9 -0.4 -2.2 0.2 -1.3 -1.2 -1.1 0.8 -1.9 -1.3 -1.4 -2.1 -2.4 -1.5 -1.2 -1.6 -1.8 -0.8 -1.5 -2.1 -1.3 -2.0 -0.4 -1.5 -1.7 -2.3
Type 2 Diabetes (T2D) (2012) 2.8 3.2 6.8 -1.4 -1.5 -1.5 -2.0 -2.1 -2.1 -2.3 -0.4 -0.8 -2.6 -2.1 -1.9 -1.5 0.6 -2.1 -2.2 -2.3 -1.5 0.6 -1.5 0.8 -2.3 0.1 -0.9 -0.7 -2.1 -0.2 -1.7 -1.9 -2.0 -2.5 -2.4 -2.0 -1.9 -1.4 -1.8 -1.7 -2.1 -2.1 -1.8 -2.4 -1.3 -2.0 -2.1 -2.3
Ulcerative Colitis 2.7 3.9 14.3 1.5 2.7 2.6 1.6 1.3 2.1 1.4 0.4 1.2 0.9 1.5 2.0 1.9 2.5 2.2 1.7 1.2 -1.0 2.6 1.2 -1.3 0.7 -0.2 3.4 3.8 1.7 0.3 2.0 2.6 2.2 1.2 1.3 2.0 -1.3 3.4 2.7 2.1 1.9 2.3 1.9 0.2 2.1 2.6 2.5 0.6
Blood Eosinophil Count 1.1 8.3 24.4 1.6 4.1 3.1 3.0 1.9 3.3 2.4 -4.9 2.0 0.3 2.1 2.9 3.9 3.5 2.8 2.6 2.4 -0.3 3.4 2.5 -1.1 1.3 -0.7 4.3 2.7 4.0 0.5 3.6 4.0 3.1 2.2 2.0 2.9 -0.6 4.4 4.0 2.9 2.7 3.3 2.6 0.8 2.5 3.9 3.7 1.1
Blood Platelet Count 0.8 8.7 38.7 4.1 1.7 1.8 3.6 3.2 2.6 2.9 -1.4 5.7 1.0 3.2 3.1 0.5 -3.8 1.7 3.1 3.2 3.1 -4.1 3.1 -3.2 1.9 -6.2 -1.1 1.1 2.1 5.6 1.8 2.0 2.9 2.5 1.8 3.5 2.7 -0.2 1.7 2.9 2.9 2.0 4.0 2.5 2.4 2.1 2.2 2.1
Blood Red Count 0.8 7.8 39.6 -2.9 -1.6 0.2 -2.0 -2.5 -2.9 -2.3 -4.4 -4.8 -2.4 -2.5 -2.4 2.6 5.6 -0.5 -2.4 -2.8 -2.4 6.0 -1.1 4.4 -1.1 6.3 3.1 -0.8 -0.6 -3.1 -0.6 -1.9 -2.5 -2.0 -1.0 -3.6 -1.9 1.3 -1.3 -2.4 -2.1 -1.1 -4.6 -2.0 -0.9 -2.0 -2.0 -1.5
Blood White Count 0.7 5.0 57.8 -2.2 0.0 -1.6 -1.3 -2.5 -1.7 -2.5 -7.6 -2.1 -3.7 -2.4 -1.6 -0.5 1.6 -3.0 -2.0 -2.7 -1.5 1.6 -2.0 -0.6 -3.4 0.5 -0.3 -0.6 0.4 1.9 -1.4 -0.5 -1.3 -2.6 -3.2 -1.3 -2.8 -0.6 -0.5 -0.8 -2.0 -1.5 -1.1 -3.4 -1.0 -0.7 -1.3 -3.6
Heel T-Score 0.3 2.6 15.8 -0.4 2.4 0.4 0.0 0.1 1.8 0.0 2.4 0.7 4.0 0.3 1.1 0.4 2.6 0.6 0.7 0.5 -1.0 2.4 0.2 -2.9 -1.2 0.5 2.4 3.4 0.5 0.5 0.9 1.9 1.6 -0.4 -0.7 1.4 -2.3 2.6 1.7 1.9 0.7 0.6 1.1 -1.6 1.0 1.7 1.3 -1.3
BMI 0.2 1.3 6.4 1.1 0.4 2.2 1.1 1.0 1.1 1.1 2.1 2.1 2.5 0.9 0.7 1.4 0.5 1.5 0.9 1.4 1.5 0.3 1.6 -0.3 1.2 -1.1 1.0 0.4 0.7 -0.6 0.8 0.5 0.8 1.0 1.3 0.7 1.2 1.1 0.7 0.7 0.9 1.0 0.2 0.9 0.7 0.6 0.7 1.4
Height 2.8 53.2 95.5 -8.9 -7.2 -6.1 -8.6 -8.1 -9.1 -8.0 -5.7 -9.8 -7.8 -8.3 -8.6 -4.4 2.7 -7.0 -8.5 -8.7 -4.2 3.2 -7.8 7.7 -5.6 8.4 -3.3 -8.1 -4.7 -7.1 -7.0 -7.6 -8.7 -7.5 -6.2 -9.2 -5.0 -4.9 -7.4 -8.3 -8.3 -7.5 -9.0 -6.1 -7.3 -7.7 -7.8 -5.8
Waist Hip Ratio (WHR) 6.4 28.9 65.3 -5.9 -3.2 -5.7 -5.9 -6.5 -5.8 -6.8 -8.1 -6.8 -5.8 -6.5 -5.4 -4.0 2.4 -6.9 -6.2 -7.2 -4.6 2.7 -5.8 2.5 -7.2 4.1 -2.0 -5.0 -2.8 -1.1 -5.5 -3.8 -5.1 -7.0 -7.0 -5.3 -5.9 -3.1 -4.1 -4.0 -6.0 -5.1 -4.9 -7.3 -3.6 -4.2 -4.9 -7.2
Systolic Blood Pressure 3.6 18.2 40.1 3.0 5.1 5.3 4.4 3.9 4.5 4.5 -4.6 1.7 0.5 4.0 4.4 6.3 4.0 5.0 4.5 4.1 1.6 3.9 3.9 -1.1 3.8 0.5 5.8 3.5 6.3 0.3 5.4 5.0 4.6 4.5 4.6 4.2 1.3 6.1 5.4 4.0 4.6 5.3 3.5 3.1 3.9 5.0 5.2 3.6
Smoking Status 0.3 0.8 4.1 -0.3 -1.3 -0.1 0.3 -0.1 -0.5 -0.0 0.4 0.9 0.7 -0.2 -0.8 -0.7 -2.0 -0.3 -0.5 0.4 0.4 -1.9 0.2 1.2 0.6 -0.2 -1.7 -1.7 -0.6 -0.7 -0.7 -1.1 -0.7 0.1 0.2 -0.5 1.2 -1.6 -1.2 -1.0 -0.6 -0.8 -0.6 0.8 -1.2 -1.0 -0.8 0.7
Allergy or Eczema 0.3 0.9 12.4 0.9 0.6 0.4 0.9 0.4 0.2 0.7 -3.5 0.4 -1.8 0.4 0.4 -0.3 -1.7 -0.2 0.6 0.3 0.7 -1.4 0.0 0.7 0.6 -1.0 -0.9 -1.1 0.5 1.2 0.3 0.6 0.4 0.9 0.6 0.8 0.6 -0.6 0.7 0.1 0.4 0.7 1.2 0.9 -0.2 0.7 0.8 0.7
Cardiovascular Disease 2.3 7.6 16.1 2.4 3.6 2.7 3.5 2.4 3.5 2.9 -3.0 2.6 0.5 2.5 2.9 3.4 1.0 3.0 2.7 3.0 0.6 1.1 2.8 -1.7 2.2 -1.7 2.8 1.5 4.0 0.7 3.0 3.6 3.2 2.9 2.9 3.2 1.0 3.2 3.8 2.6 2.9 3.7 3.1 1.8 2.2 3.6 3.7 2.5
Hypothyroidism (self reported) 0.3 0.8 3.5 0.1 1.5 -0.7 0.5 0.1 0.9 0.0 -1.9 -0.1 1.2 0.2 0.8 -0.7 0.0 -0.2 0.5 0.2 -1.1 -0.0 0.3 -1.5 -1.0 -0.3 0.5 -0.5 1.1 0.9 0.4 1.2 1.1 -0.3 -0.7 1.3 -1.4 0.7 1.1 1.3 0.5 0.5 1.6 -1.0 0.7 1.1 0.9 -0.9
Respiratory disease 0.8 1.9 3.6 1.7 1.5 1.1 1.9 1.4 1.5 1.7 -0.4 0.7 0.5 1.5 1.4 1.5 0.2 1.4 1.6 1.6 0.3 0.2 1.7 -1.5 1.4 -1.4 1.0 1.1 1.7 1.2 1.9 1.3 1.6 1.6 1.4 1.6 0.7 1.3 1.5 1.4 1.5 1.4 1.4 1.4 1.0 1.4 1.4 1.3
Type 2 Diabetes (T2D) (2018) 0.6 1.2 9.3 -0.4 0.5 -1.9 -1.0 -0.9 -0.3 -1.0 -3.1 -0.9 -2.3 -0.9 -0.3 -1.4 0.5 -1.1 -0.7 -1.0 -0.2 0.4 -1.5 -1.2 -1.7 -1.0 -0.2 0.2 0.9 1.2 -0.7 0.2 -0.1 -1.2 -1.4 -0.1 -1.8 0.1 0.2 0.2 -0.6 -0.3 0.2 -1.8 0.0 0.1 -0.2 -1.7
Lung FEV1/FVC ratio 3.2 16.3 44.2 -4.7 -1.1 -5.5 -5.1 -5.2 -3.5 -5.3 -4.3 -4.4 -1.0 -5.2 -3.8 -2.7 1.9 -5.9 -4.5 -5.5 -3.9 2.1 -5.2 -0.0 -6.4 1.8 -1.7 -2.8 -2.4 -0.5 -4.5 -1.8 -3.1 -5.7 -5.9 -3.0 -5.1 -1.8 -2.2 -2.3 -4.6 -3.9 -3.0 -6.7 -3.2 -2.2 -3.0 -6.3
Lung FVC 1.1 5.7 18.1 2.3 2.0 1.8 2.4 2.8 2.9 2.7 4.2 3.5 3.5 2.7 2.7 0.5 -0.9 2.5 2.7 3.0 2.5 -1.4 1.9 -1.7 2.1 -2.0 0.8 1.9 1.2 1.4 2.0 2.1 2.8 2.5 2.3 2.8 1.6 1.6 2.1 2.6 2.6 2.4 2.9 2.2 2.3 2.2 2.4 2.4
Neuroticism 4.1 9.9 15.8 4.0 3.2 3.6 3.6 3.3 3.8 3.7 -1.4 3.9 0.4 3.4 3.4 3.2 -1.2 3.2 3.6 3.6 1.6 -1.3 3.2 -1.9 3.1 -3.6 1.3 1.3 3.5 1.4 3.0 3.5 3.6 3.6 3.5 3.9 3.0 2.2 3.5 3.1 3.5 3.9 3.9 3.0 2.6 3.6 3.9 3.4
Chronotype (morning person) 0.7 1.7 7.8 -1.0 -0.3 -1.0 -1.5 -1.5 -0.8 -1.8 -0.4 -0.5 -1.2 -1.4 -1.0 -0.8 1.9 -1.5 -1.3 -1.5 -0.9 1.8 -0.3 -0.1 -2.3 -0.3 0.4 0.1 -0.5 1.2 -0.8 -0.5 -1.0 -2.0 -2.4 -1.3 -2.0 -0.1 -0.8 -0.4 -1.3 -1.4 -1.3 -2.4 -0.0 -0.7 -1.1 -2.8
Hair Pigment 0.3 7.2 49.0 3.1 1.0 0.6 1.7 2.0 1.9 1.8 2.3 4.4 1.2 1.9 1.9 -2.7 -5.9 0.2 2.0 1.9 2.8 -6.4 1.1 -3.9 0.9 -7.0 -3.6 -0.3 0.8 4.7 0.1 1.3 2.0 1.7 0.9 3.1 2.2 -2.0 1.1 1.8 1.6 1.2 4.0 1.8 0.7 1.4 1.5 1.6
Tanning 0.1 1.3 7.9 -0.9 -1.4 0.7 -0.5 -0.1 -1.3 -0.2 1.6 -1.6 -1.1 -0.1 -0.7 1.4 1.6 0.8 -0.3 -0.3 -0.9 1.8 0.4 1.6 0.9 2.8 1.2 0.7 -1.0 -2.7 -0.1 -1.6 -1.0 -0.0 0.5 -1.5 0.1 0.5 -1.1 -0.9 -0.3 -0.9 -1.9 0.6 -0.3 -1.5 -1.2 0.5
Hand grip strength (left) 1.8 4.7 11.0 1.7 2.5 1.7 2.3 2.4 2.5 2.4 -0.0 1.1 1.3 2.3 2.6 1.6 0.4 2.3 2.6 2.1 2.6 0.4 1.5 -0.5 1.8 -1.1 2.1 1.3 3.3 1.7 2.2 2.7 2.6 2.3 2.3 2.6 0.7 2.5 2.8 2.4 2.6 2.9 2.7 1.6 2.5 2.7 2.9 2.0
Number of treatments/medications taken 0.6 1.0 4.9 0.5 0.2 1.4 1.9 0.6 0.7 1.1 -1.8 1.8 -0.2 0.6 0.2 1.6 -0.7 1.3 0.5 1.4 -0.0 -0.5 2.2 -0.3 1.6 -0.5 -0.0 -1.0 0.7 -0.4 0.9 0.2 0.2 1.3 1.5 0.4 1.1 0.1 0.4 -0.4 0.5 0.6 0.4 1.6 -0.8 0.3 0.6 1.7
Average weekly spirits intake 0.7 0.8 6.1 -0.9 -0.4 -0.5 -0.6 -1.0 -0.9 -1.0 -1.7 -1.0 -1.2 -0.9 -0.8 -0.7 -0.4 -0.8 -1.0 -0.8 -2.5 -0.3 -0.6 -0.6 -1.1 0.8 -0.6 -1.1 -0.5 -1.1 -1.2 -0.6 -0.6 -1.0 -0.8 -0.5 -1.2 -0.6 -0.6 -0.5 -0.8 -0.8 -0.3 -1.0 -0.8 -0.6 -0.6 -0.7
Sensitivity / hurt feelings 5.5 9.3 17.7 3.4 3.1 3.3 4.2 3.4 3.3 3.6 -2.0 2.3 0.7 3.4 3.4 4.0 0.8 3.7 3.4 3.5 1.3 0.9 3.5 -1.0 3.2 -1.0 3.1 2.4 3.2 0.9 3.4 3.3 3.5 3.5 3.6 3.3 1.9 3.3 3.4 3.1 3.5 3.7 3.0 2.9 3.1 3.4 3.6 3.2
Frequency of depressed mood in last 2 weeks 0.7 1.0 6.9 1.1 0.3 0.4 0.8 0.6 0.8 0.8 -1.0 2.6 0.6 0.7 0.5 -0.1 -2.0 0.5 0.7 1.1 0.6 -2.0 0.7 0.4 0.8 -2.3 -1.0 -1.1 0.1 -0.0 0.1 0.6 0.5 1.0 0.9 0.8 1.4 -0.8 0.6 0.2 0.6 1.0 1.2 1.1 0.2 0.7 0.9 1.2
Hearing difficulty/problems: Yes 0.5 0.8 7.1 0.8 1.0 1.0 0.5 0.5 1.0 0.8 -2.7 1.6 -0.5 0.6 0.7 -0.2 -0.7 0.7 0.4 0.8 -0.6 -0.7 -0.1 0.0 0.5 -1.2 -0.1 0.1 1.3 -0.3 0.6 1.2 0.8 0.8 0.8 1.1 0.2 0.4 1.0 0.5 0.7 1.0 1.4 0.5 0.1 1.2 1.3 0.8
Relative age of first facial hair 0.3 0.5 2.2 -0.3 -1.0 -0.7 -0.8 -0.4 -1.0 -0.7 0.6 -0.0 0.4 -0.4 -0.6 -0.4 0.5 -0.6 -0.6 -0.7 -0.3 0.4 -0.5 1.0 -0.5 -0.1 -0.0 -0.6 -1.0 -1.5 -0.5 -1.2 -0.7 -0.8 -0.7 -0.9 -0.7 -0.3 -1.1 -0.4 -0.6 -1.2 -1.0 -0.5 -0.2 -1.2 -1.1 -0.7
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 1.4 1.1 0.0 1.1 0.9 0.8 0.4 0.8 1.2 -0.0 -0.9 0.6 0.5 0.3 -0.5 0.6 0.6 0.5 1.1 -0.5 1.0 0.9 1.0 0.1 0.2 -0.6 0.3 0.6 0.3 0.4 0.5 0.7 0.9 0.4 1.2 0.2 0.3 0.5 0.6 0.8 0.5 0.8 0.8 0.4 0.6 0.9
Ever used hormone-replacement therapy (HRT) 1.6 2.0 5.9 0.7 0.8 2.0 1.4 1.2 1.4 1.5 2.1 2.4 1.9 1.1 0.7 1.4 -1.5 2.0 1.2 1.8 1.8 -1.4 1.9 -0.9 2.0 -1.2 -0.3 1.6 0.4 -0.8 0.9 0.7 0.8 1.9 2.1 1.2 1.9 0.2 1.1 0.0 1.0 1.2 0.9 2.1 -0.6 0.9 1.2 2.4
Ever had hysterectomy (womb removed) 1.0 1.2 5.7 -1.4 -0.7 0.5 -1.1 -1.5 -0.8 -0.9 -0.5 0.5 -1.9 -1.6 -1.6 -0.5 -1.2 -0.6 -1.5 -1.1 -0.5 -0.8 -1.5 0.2 -0.3 -0.2 -1.6 -0.2 -1.3 -1.2 -1.2 -0.5 -1.4 -0.5 -0.2 -1.0 0.5 -1.5 -0.5 -2.0 -1.4 -0.3 -0.9 -0.4 -2.4 -0.5 -0.4 0.1
Systolic blood pressure, automated reading 1.5 4.4 14.9 0.9 2.3 3.1 2.0 1.8 1.9 2.1 -3.3 0.7 -0.5 1.7 1.8 3.4 2.0 2.7 1.9 2.0 1.8 2.0 2.0 0.0 2.2 0.6 2.7 1.6 3.9 0.2 2.5 2.2 1.9 2.3 2.5 1.7 0.9 2.9 2.6 1.4 2.0 2.6 1.3 1.7 1.3 2.3 2.4 2.1
Eye problems/disorders: Diabetes related eye disease 0.5 0.5 3.2 -0.4 -0.4 -1.8 -0.2 -0.3 -0.8 -0.6 -0.5 -1.8 0.5 -0.4 -0.4 -1.4 -0.5 -1.0 -0.4 -0.8 -0.4 -0.5 -1.1 -0.7 -0.6 0.9 -0.6 -0.1 -0.6 1.3 -0.6 -0.6 -0.4 -0.5 -0.8 -0.4 -0.8 -0.7 -0.5 -0.2 -0.4 -0.8 -0.2 -0.4 -0.3 -0.6 -0.7 -0.8
Angina 2.3 3.0 6.4 -1.3 -1.6 -2.5 -0.9 -1.6 -2.0 -1.9 -1.3 -1.2 -0.5 -1.7 -1.6 -1.7 -1.7 -2.5 -1.8 -1.8 -0.8 -1.7 -1.9 -0.7 -1.9 0.4 -2.3 -1.8 -2.0 1.2 -2.4 -1.9 -1.4 -2.1 -2.2 -1.2 -0.8 -2.2 -2.0 -1.1 -1.8 -2.3 -1.2 -1.7 -1.6 -1.9 -2.1 -1.8
Medication for hormone replacement therapy 0.5 0.5 3.1 0.2 0.0 0.8 0.7 0.6 0.2 0.7 0.7 -0.2 1.8 0.6 0.3 1.2 -0.8 0.7 0.7 0.7 -0.2 -0.8 1.4 -1.4 1.0 0.3 -0.2 -0.9 0.5 -0.4 0.3 -0.1 0.3 0.8 0.9 0.3 1.4 -0.1 0.3 0.1 0.5 0.4 0.1 1.0 -0.0 0.0 0.2 1.2
Vitamin and mineral supplements 0.5 0.6 4.3 -0.5 0.1 -0.5 -0.7 -0.6 -0.3 -0.6 -0.7 -0.5 -1.3 -0.5 -0.3 0.4 2.1 -0.3 -0.5 -0.8 -0.7 2.1 -0.9 1.2 -0.7 1.1 1.1 0.9 -0.8 -0.7 0.0 0.1 -0.3 -0.7 -0.6 -0.6 -1.1 0.7 -0.0 -0.1 -0.4 -0.2 -0.8 -1.0 0.2 0.0 -0.2 -0.9
Supplements: Zinc 0.2 0.2 1.9 -0.0 0.1 -0.5 0.2 -0.0 0.0 -0.3 1.1 0.0 0.6 -0.1 0.1 0.3 -0.2 -0.4 0.0 -0.4 0.4 -0.2 0.4 -1.4 -0.7 -0.5 -0.1 0.3 0.1 0.6 -0.3 0.1 0.2 -0.5 -0.6 0.2 -0.2 -0.1 -0.2 0.5 -0.1 -0.5 0.1 -0.6 0.2 0.0 -0.1 -0.6
Medication: Co-codamol 0.6 0.6 2.3 -0.8 -0.8 -0.5 -0.3 -1.0 -0.8 -0.7 0.3 -0.7 0.3 -1.0 -1.1 0.7 0.5 -0.6 -0.8 -0.7 -0.5 0.7 0.2 1.1 -0.1 0.9 -0.2 -0.4 -1.5 -1.5 -0.7 -0.9 -1.1 -0.5 -0.3 -1.2 0.2 -0.5 -0.6 -1.3 -1.0 -0.4 -1.4 -0.3 -1.2 -0.9 -0.8 -0.2
Medication: Metformin 0.8 1.1 4.0 -0.7 0.2 -1.5 -1.0 -1.2 -0.4 -1.0 -1.7 -0.7 -1.8 -1.1 -0.7 -2.0 -0.9 -1.3 -1.0 -1.2 -1.0 -0.9 -1.6 -1.5 -1.5 -1.4 -1.3 0.4 -0.1 0.9 -1.0 0.0 -0.5 -1.0 -1.2 -0.1 -1.4 -1.0 -0.2 -0.6 -0.9 -0.6 0.4 -1.3 -1.1 -0.1 -0.2 -1.2
Diabetes (father) 0.6 0.8 2.9 -1.1 0.2 -1.7 -0.8 -1.0 -0.4 -1.1 -0.4 -0.8 0.9 -1.1 -0.6 -0.2 0.6 -1.1 -0.9 -1.0 -0.6 0.5 -1.2 -0.8 -1.6 0.9 -0.2 0.5 -0.5 -0.5 -1.0 -0.1 -0.2 -1.3 -1.3 -0.2 -1.6 0.2 -0.3 -0.1 -0.9 -0.8 -0.4 -1.7 -0.7 -0.2 -0.4 -1.4
Diabetes (mother) 1.3 1.6 5.4 -1.0 -1.3 -1.5 -1.1 -1.3 -1.1 -0.9 -1.4 0.2 -1.3 -1.4 -1.5 -1.8 -1.7 -1.4 -1.3 -1.4 0.9 -1.5 -1.0 1.6 -0.4 -0.7 -2.1 -2.3 -0.9 0.6 -1.2 -0.8 -1.6 -0.6 -0.4 -1.2 0.5 -2.2 -1.0 -2.1 -1.4 -0.5 -0.6 -0.1 -1.9 -0.7 -0.6 -0.1
Severe depression (siblings) 1.5 1.6 4.2 1.4 0.7 1.6 1.3 1.4 1.3 1.6 0.3 1.8 1.0 1.4 1.2 1.1 -0.6 1.7 1.3 1.6 0.8 -0.5 1.8 0.6 1.8 -0.5 0.6 0.3 1.1 -0.1 1.0 1.1 1.1 1.7 1.9 1.1 1.8 0.7 1.2 0.7 1.4 1.8 1.1 1.7 1.1 1.2 1.4 2.0
Pack years adult smoking proportion 0.4 0.5 2.0 1.0 -0.1 0.5 1.3 1.0 0.2 0.9 -0.7 0.3 0.5 1.0 0.6 0.7 -0.8 0.5 1.0 0.9 0.7 -0.9 1.4 1.0 1.1 0.0 -0.1 -0.7 0.2 0.0 0.8 0.1 0.4 1.0 0.9 0.4 1.1 -0.1 0.1 0.3 0.8 0.4 0.6 1.3 0.6 0.1 0.3 1.0
Impedance of leg (right) 1.8 8.7 20.4 -2.8 -1.1 -3.5 -3.1 -3.5 -2.7 -3.7 -4.4 -4.1 -4.2 -3.3 -2.5 -2.4 0.7 -4.2 -3.2 -4.0 -3.3 0.7 -3.6 0.0 -4.5 2.1 -1.7 -1.8 -1.9 0.8 -3.0 -1.5 -2.3 -3.9 -4.3 -2.1 -3.6 -1.8 -1.9 -1.5 -3.0 -2.8 -1.7 -4.4 -1.8 -1.8 -2.3 -4.5
Leg fat-free mass (left) 0.9 4.6 15.1 -2.8 -2.9 -1.0 -2.4 -2.0 -2.6 -1.9 1.4 -1.9 0.7 -2.1 -2.7 -1.0 0.9 -1.0 -2.2 -1.7 -0.4 1.1 -1.3 3.0 -0.4 2.9 -0.6 -2.8 -1.6 -3.9 -1.7 -2.9 -2.9 -1.6 -0.8 -3.2 -0.4 -1.4 -2.6 -3.0 -2.3 -2.3 -3.5 -0.7 -2.4 -2.8 -2.6 -0.5
Trunk fat percentage 1.3 5.1 12.2 -2.6 -2.6 -1.2 -2.3 -2.5 -2.6 -2.6 0.1 -2.7 -1.2 -2.6 -2.8 -1.2 0.7 -1.8 -2.7 -2.3 -1.4 0.8 -1.1 1.1 -1.8 3.5 -1.0 -1.6 -2.3 -2.2 -2.1 -2.8 -2.8 -2.6 -2.1 -3.0 -1.4 -1.7 -2.9 -2.6 -2.7 -3.0 -3.2 -2.0 -2.5 -2.8 -2.8 -1.9
Hand grip strength (right) 2.1 5.6 9.4 2.3 2.2 2.1 2.7 2.8 2.4 2.9 0.8 0.7 1.0 2.7 2.7 2.2 0.5 2.7 3.0 2.4 2.7 0.4 2.4 -0.6 2.8 -0.5 2.2 1.4 3.1 1.3 2.8 2.5 2.6 2.9 3.0 2.5 1.5 2.5 2.6 2.4 2.8 3.0 2.5 2.5 2.5 2.6 2.8 2.7
Townsend deprivation index at recruitment 0.5 0.7 3.6 -0.8 -0.4 -0.2 -0.4 -0.7 -0.3 -0.7 1.8 0.0 0.9 -0.5 -0.6 0.2 1.1 -0.0 -0.6 -0.4 -1.9 1.0 0.1 -1.3 -0.6 0.6 0.5 1.0 -1.3 -1.4 0.0 -0.6 -0.6 -0.8 -0.8 -0.7 -0.9 0.1 -0.7 -0.5 -0.6 -1.1 -1.0 -0.7 -0.5 -0.7 -0.8 -0.9
Current tobacco smoking 1.6 2.6 4.8 -1.6 -1.4 -2.1 -1.0 -1.9 -1.7 -1.7 -1.3 -1.2 -0.3 -1.8 -1.9 -1.6 -1.3 -2.1 -1.8 -1.6 -2.1 -1.2 -1.0 0.1 -1.5 0.8 -2.1 -1.9 -2.0 -0.9 -1.8 -1.4 -1.7 -1.6 -1.7 -1.4 -1.1 -2.1 -1.8 -1.7 -1.9 -2.0 -1.1 -1.3 -2.2 -1.5 -1.6 -1.5
Average weekly fortified wine intake 1.3 1.5 5.0 0.9 0.6 1.2 1.3 1.4 1.1 1.7 -0.3 1.7 1.5 1.4 1.0 0.9 -1.2 1.7 1.3 1.6 0.5 -1.0 0.7 -0.7 2.0 -0.7 0.1 0.8 1.1 -0.4 1.1 0.7 1.0 1.9 2.0 1.1 1.7 0.3 0.9 0.5 1.3 1.2 1.0 2.1 0.3 0.9 1.1 2.2
Maternal smoking around birth 0.3 0.5 12.8 -0.2 0.0 -0.0 -0.5 -0.3 0.2 -0.4 3.6 0.4 0.3 -0.1 -0.1 -0.2 0.3 0.2 -0.1 -0.1 -0.8 0.5 0.9 -0.4 -0.6 -0.2 0.4 1.1 -0.8 -1.1 -0.3 -0.1 -0.1 -0.5 -0.5 -0.2 -0.9 0.2 -0.2 0.1 -0.2 -0.6 -0.1 -0.6 0.1 -0.1 -0.1 -0.6
Fed-up feelings 1.3 2.4 7.5 2.4 0.8 1.4 1.8 1.7 1.3 2.0 -0.7 1.6 0.5 1.7 1.4 1.8 -1.9 1.5 1.7 1.6 0.8 -1.8 1.8 -0.1 2.2 -1.4 -0.3 -0.6 0.7 -0.1 1.0 1.2 1.4 2.2 2.3 1.6 2.7 0.2 1.2 0.8 1.6 1.9 1.6 2.3 0.7 1.4 1.6 2.6
Frequency of unenthusiasm / disinterest in last 2 weeks 2.0 2.7 8.5 2.3 1.7 0.9 1.8 1.4 1.9 1.6 -1.7 2.7 1.7 1.5 1.7 0.8 -1.3 1.2 1.8 1.8 0.5 -1.3 2.4 -1.0 0.9 -2.9 0.2 0.0 1.6 0.9 1.1 2.0 1.8 1.5 1.3 2.1 1.0 0.7 1.9 1.7 1.6 2.1 2.3 1.0 1.6 2.0 2.0 1.3
Relative age voice broke 0.5 0.8 5.9 -0.0 -1.0 0.4 -0.1 0.4 -0.4 0.3 1.6 -0.2 0.5 0.2 -0.2 1.2 0.5 0.6 0.2 0.2 1.6 0.7 0.3 2.4 1.2 1.0 0.5 -1.2 -0.0 -2.3 0.3 -0.8 -0.5 0.6 1.0 -0.8 1.4 0.1 -0.5 -0.6 0.1 0.2 -1.1 1.0 0.2 -0.7 -0.4 1.1
Taking other prescription medications 0.5 0.7 4.1 0.5 0.8 1.3 0.8 0.1 0.9 0.4 -0.6 1.4 -0.0 0.2 0.3 1.9 1.4 1.2 0.4 0.8 -0.4 1.4 2.0 -0.6 0.4 -0.4 1.3 0.7 0.9 -1.1 0.7 0.7 0.4 0.3 0.6 0.3 -0.2 1.2 0.8 0.3 0.3 0.8 -0.0 0.0 0.2 0.7 0.7 0.4
Age when periods started (menarche) 0.9 2.3 9.8 -1.7 0.4 -1.5 -1.9 -1.7 -1.0 -1.7 -0.6 -3.1 -2.0 -1.7 -1.0 -0.4 1.9 -1.7 -1.5 -2.4 -1.7 1.8 -2.5 -0.6 -2.3 1.4 0.3 0.9 -0.8 -0.4 -0.9 0.1 -0.6 -1.9 -2.0 -0.6 -2.6 0.4 -0.2 -0.4 -1.3 -1.0 -0.7 -2.6 -0.9 -0.1 -0.5 -2.3
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 2.7 -0.1 -0.6 1.4 0.4 0.1 -0.2 0.6 0.1 1.3 -1.1 0.0 -0.5 1.1 -0.1 1.4 -0.1 0.5 0.8 0.3 0.4 1.3 1.6 0.6 0.1 1.1 -0.5 -1.6 0.3 -0.5 -0.6 1.0 1.4 -0.6 1.4 -0.1 -0.1 -1.1 -0.1 0.4 -0.8 1.4 -1.0 -0.3 -0.0 1.6
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.6 3.6 -0.8 0.2 -1.1 -0.8 -0.7 -0.2 -0.9 0.7 -1.9 0.5 -0.8 -0.3 -0.5 1.0 -1.0 -0.5 -1.0 0.3 0.8 -0.2 -0.9 -1.5 1.0 0.2 0.1 -0.0 1.3 -0.5 0.2 -0.2 -1.2 -1.2 -0.2 -1.3 0.2 -0.1 0.1 -0.6 -0.3 -0.3 -1.6 0.2 0.1 -0.2 -1.4
Tinnitus: Yes, but not now, but have in the past 7.1 7.5 13.6 -2.9 -3.6 -2.0 -2.6 -2.8 -3.2 -2.8 1.1 -0.8 -2.1 -2.9 -3.4 -2.9 -1.7 -2.6 -3.1 -2.6 -0.6 -1.3 -1.9 3.2 -1.6 1.1 -3.0 -3.3 -3.7 -1.9 -3.1 -3.5 -3.6 -2.5 -2.2 -3.5 -0.4 -3.7 -3.5 -3.5 -3.2 -3.0 -3.0 -1.4 -3.1 -3.5 -3.4 -1.6
Qualifications: CSEs or equivalent 3.6 4.8 9.3 -2.6 -2.2 -1.5 -2.5 -2.6 -2.7 -2.7 -0.6 -2.0 -2.3 -2.7 -2.6 -0.8 0.8 -2.2 -2.7 -2.9 -1.0 1.0 -2.1 1.3 -2.3 1.9 -1.0 -0.7 -2.2 -1.8 -2.6 -2.3 -2.6 -2.7 -2.5 -2.8 -1.2 -1.6 -2.2 -2.2 -2.7 -2.3 -3.0 -2.5 -1.8 -2.4 -2.6 -2.4
Serious illness, injury or assault to yourself 0.4 0.4 2.2 -0.1 -0.1 -0.0 -0.3 -0.6 0.1 -0.1 -1.0 0.7 -1.3 -0.6 -0.6 -1.2 -1.2 -0.3 -0.4 -0.1 -0.0 -1.0 0.2 1.4 0.1 -1.0 -1.1 -1.5 0.0 -0.0 -0.4 0.2 -0.6 0.1 0.2 -0.2 -0.0 -0.9 0.1 -1.1 -0.5 0.3 0.3 0.2 -1.0 0.2 0.4 0.2
High blood pressure 3.0 8.3 21.0 2.1 3.0 4.0 3.6 2.6 3.1 3.2 -2.7 1.4 0.6 2.6 2.6 4.6 1.9 3.8 2.7 3.1 0.9 2.1 3.4 -0.6 3.2 0.7 3.5 1.8 4.2 -0.1 3.4 3.0 2.8 3.4 3.7 2.6 2.1 3.6 3.5 2.2 2.9 3.8 2.0 2.7 2.1 3.2 3.4 3.3
Hayfever, allergic rhinitis or eczema 0.3 0.6 4.8 0.9 -0.1 0.1 0.9 0.4 -0.3 0.7 -2.2 0.2 -1.1 0.4 0.1 -0.0 -1.6 0.0 0.5 0.2 0.6 -1.4 0.4 0.9 1.0 -0.4 -0.9 -1.2 -0.0 0.5 0.3 -0.0 0.0 0.9 0.8 0.3 1.1 -0.7 0.2 -0.2 0.3 0.6 0.6 1.2 -0.2 0.1 0.3 1.1
Multivitamins +/- minerals 0.4 0.5 2.8 0.6 0.0 0.6 0.7 0.7 0.5 0.6 0.4 1.2 1.7 0.7 0.5 -0.3 -1.4 0.6 0.5 1.0 0.5 -1.4 0.8 -0.8 0.6 -1.0 -0.5 -0.5 1.0 0.8 0.1 -0.1 0.5 0.6 0.6 0.6 0.9 -0.3 0.2 0.5 0.6 0.4 0.6 0.8 0.4 0.0 0.2 0.8
Stomach or abdominal pain in last month 0.8 1.0 4.0 0.7 1.1 0.1 0.8 0.3 0.7 -0.0 -0.3 0.7 2.0 0.4 0.9 1.2 1.6 0.1 0.6 0.3 -0.4 1.5 1.2 -1.6 -0.9 -1.5 1.5 1.3 0.8 1.6 0.5 0.7 1.0 -0.4 -0.8 0.7 -1.4 1.4 0.7 1.5 0.5 0.0 0.4 -1.0 1.3 0.6 0.3 -1.1
Supplements: Glucosamine 2.9 3.8 12.6 2.3 0.2 1.8 2.2 2.3 1.6 2.3 2.2 3.6 1.6 2.3 1.6 0.5 -2.4 1.9 2.1 2.7 1.8 -2.4 3.2 -0.2 2.6 -3.5 -0.5 -0.8 1.1 1.1 1.7 0.6 1.3 2.4 2.2 1.5 2.6 -0.3 0.7 1.0 1.9 1.4 1.9 2.9 1.4 0.7 1.1 2.5
Diverticular disease/diverticulitis (self-reported) 0.5 0.5 2.4 -0.6 0.3 -0.7 -0.7 -1.1 -0.3 -0.9 -0.9 0.1 -0.5 -1.0 -0.6 0.6 1.4 -0.8 -0.7 -0.9 -0.7 1.6 0.3 -0.4 -1.2 -0.2 0.4 -0.3 -0.1 -0.4 -0.2 0.1 -0.5 -0.9 -1.0 -0.5 -1.0 0.3 0.1 -0.4 -0.8 -0.4 -0.7 -1.4 -0.7 -0.0 -0.3 -1.3
Medication: Atenolol 0.6 0.7 10.8 -1.0 0.7 -0.1 0.0 -0.6 -0.1 -0.5 -3.3 -1.2 -1.6 -0.6 -0.2 0.9 0.9 -0.6 -0.6 -0.7 -0.7 0.9 -1.1 -1.4 -0.9 1.1 0.2 0.8 0.6 0.4 0.2 0.4 0.1 -0.6 -0.8 0.1 -0.8 0.3 0.3 0.0 -0.4 -0.3 -0.2 -1.0 -0.5 0.3 0.1 -0.9
Medication: Levothyroxine sodium 0.4 0.7 3.4 0.2 1.5 -0.6 0.2 -0.1 0.8 -0.2 -1.3 -0.0 0.3 0.0 0.6 -0.6 0.2 -0.5 0.4 -0.0 -1.1 0.1 0.3 -1.8 -1.2 -0.8 0.3 -0.1 0.7 0.8 0.1 1.2 0.8 -0.4 -0.9 1.0 -1.8 0.6 1.0 1.1 0.3 0.2 1.5 -1.1 0.5 1.1 0.8 -1.3
Sitting height 0.3 2.1 21.1 -0.9 -0.4 -0.3 -0.5 0.1 -1.3 -0.1 -3.2 -4.6 -1.7 -0.1 -0.2 1.6 2.8 0.0 0.1 -0.7 0.4 3.0 -0.4 1.5 0.4 3.9 2.0 -1.5 2.1 -0.7 0.7 -0.7 -0.4 -0.1 0.2 -1.0 -0.5 1.3 -0.3 -0.2 0.0 -0.4 -1.5 0.1 0.5 -0.7 -0.6 -0.1
Chronic bronchitis/emphysema (father) 0.8 1.0 4.6 -0.8 -0.7 -0.7 -0.7 -0.8 -0.4 -0.7 0.2 0.8 0.0 -0.9 -1.0 -1.6 -1.9 -1.1 -0.9 -0.6 0.6 -1.8 -1.1 1.7 -0.6 -1.1 -1.9 -2.1 -0.6 -0.4 -1.2 -0.5 -0.9 -0.5 -0.5 -0.5 0.3 -1.7 -0.6 -1.1 -0.9 -0.4 -0.2 -0.3 -1.2 -0.5 -0.4 -0.2
High blood pressure (mother) 0.6 0.8 3.9 0.3 0.2 1.6 0.7 0.4 0.5 0.9 -0.2 1.1 -0.4 0.4 0.2 1.2 -0.3 1.4 0.4 0.6 0.7 -0.1 0.6 1.5 1.5 -0.1 0.3 -0.1 -0.0 -2.0 0.6 0.5 0.1 1.2 1.8 0.2 1.4 0.3 0.7 -0.5 0.5 1.5 0.3 1.3 -0.2 0.7 1.0 1.9
Body mass index (BMI) 0.1 0.5 3.9 -0.1 -0.4 1.1 0.3 0.2 0.3 0.3 1.8 0.6 2.0 0.1 -0.2 0.8 0.7 1.1 0.1 0.7 1.1 0.7 1.4 0.7 0.9 0.5 0.8 -0.3 0.2 -1.4 0.4 -0.3 -0.2 0.4 0.9 -0.5 0.7 0.5 -0.1 -0.4 0.0 0.2 -0.8 0.6 -0.2 -0.2 -0.0 0.9
Impedance of leg (left) 1.3 6.3 23.0 -2.2 -0.4 -3.1 -2.4 -2.8 -2.1 -3.0 -4.8 -3.7 -4.0 -2.7 -1.8 -1.9 0.8 -3.5 -2.5 -3.4 -3.0 0.9 -2.8 -0.5 -4.0 1.9 -1.1 -0.9 -1.4 1.4 -2.1 -0.8 -1.6 -3.2 -3.8 -1.4 -3.5 -1.2 -1.2 -1.0 -2.4 -2.3 -1.0 -3.8 -1.4 -1.1 -1.7 -4.0
Leg predicted mass (left) 0.9 4.7 15.5 -2.9 -2.9 -1.0 -2.4 -2.0 -2.6 -1.9 1.5 -1.9 0.6 -2.1 -2.7 -1.0 0.9 -1.0 -2.2 -1.7 -0.3 1.2 -1.3 2.9 -0.4 2.9 -0.5 -2.7 -1.6 -3.9 -1.7 -2.9 -2.9 -1.6 -0.8 -3.3 -0.5 -1.4 -2.6 -3.0 -2.3 -2.3 -3.5 -0.7 -2.4 -2.8 -2.6 -0.6
Trunk fat mass 1.6 6.9 15.1 -3.2 -3.1 -1.4 -2.8 -2.9 -3.2 -2.9 0.0 -3.1 -1.1 -3.0 -3.3 -1.4 0.9 -2.1 -3.1 -2.7 -1.2 1.0 -1.5 2.0 -1.8 3.9 -1.1 -2.6 -2.4 -2.9 -2.5 -3.3 -3.4 -2.8 -2.1 -3.6 -1.4 -1.9 -3.3 -3.2 -3.1 -3.2 -3.8 -2.0 -3.0 -3.3 -3.2 -1.8
Waist circumference 1.6 5.8 10.5 -2.8 -2.6 -1.7 -2.6 -2.8 -2.9 -2.8 -0.9 -2.4 -0.8 -3.0 -3.1 -1.6 0.7 -2.2 -2.9 -2.7 -1.0 0.9 -1.5 2.3 -1.9 2.5 -1.1 -2.9 -1.8 -2.7 -2.6 -2.7 -3.0 -2.7 -2.1 -3.2 -1.6 -1.8 -2.7 -2.9 -3.0 -2.7 -3.2 -2.2 -2.7 -2.7 -2.7 -1.9
Number of incorrect matches in round 0.4 0.7 3.4 -0.9 -1.1 0.0 -0.3 -0.6 -0.6 -0.3 1.4 0.4 -0.9 -0.7 -1.1 -0.3 -1.4 -0.2 -0.7 -0.4 0.5 -1.4 -0.5 0.5 0.4 -0.0 -1.6 0.1 -1.1 0.4 -0.8 -1.0 -1.0 -0.0 0.3 -0.8 0.8 -1.4 -0.9 -1.4 -0.9 -0.6 -0.8 0.5 -1.9 -0.9 -0.7 0.7
Past tobacco smoking 0.5 0.9 5.7 -0.4 1.0 -0.5 -0.8 -1.0 -0.1 -0.8 -1.8 -1.4 -0.2 -0.8 -0.2 -0.0 1.6 -0.7 -0.5 -1.2 -2.4 1.8 -0.4 -0.7 -1.3 0.8 0.9 0.1 0.0 0.2 -0.1 0.8 -0.0 -0.8 -0.8 -0.0 -1.8 0.8 0.8 0.0 -0.4 0.3 0.2 -1.5 -0.0 0.7 0.5 -1.3
Alcohol usually taken with meals 0.3 0.5 4.2 -0.6 -1.1 -0.3 0.1 -0.4 -0.8 -0.3 -1.1 -0.2 0.8 -0.4 -0.7 0.0 -1.1 -0.4 -0.4 -0.2 -0.3 -1.0 0.4 1.3 0.3 0.2 -1.0 -2.0 -0.7 -0.2 -0.6 -0.7 -0.9 -0.1 0.1 -0.8 0.7 -1.2 -0.9 -1.1 -0.6 -0.4 -0.6 0.4 -0.6 -0.7 -0.5 0.4
Nervous feelings 0.4 0.7 7.7 1.3 1.0 -0.5 0.2 -0.2 0.6 0.1 -1.8 0.5 -2.8 -0.0 0.4 -0.3 -0.5 -0.4 0.1 -0.1 -1.2 -0.6 -0.2 -0.8 -0.5 -2.0 -0.6 0.3 0.1 1.7 0.2 1.1 0.6 0.1 -0.3 0.9 -0.4 -0.0 0.9 0.5 0.2 0.6 1.2 -0.4 0.2 1.0 0.9 -0.5
Frequency of tenseness / restlessness in last 2 weeks 2.7 4.2 8.7 2.0 2.6 2.5 2.1 1.6 2.8 2.2 -2.4 2.9 -0.5 1.7 1.9 1.8 -0.6 2.1 2.0 2.3 0.3 -0.5 1.8 -1.3 1.6 -2.4 0.8 0.8 2.6 0.1 1.9 2.8 2.2 2.3 2.2 2.5 1.4 1.4 2.9 1.7 2.0 3.0 2.7 1.6 1.2 2.9 2.9 2.1
Hearing difficulty/problems with background noise 1.3 2.1 7.2 1.6 0.2 1.8 1.5 1.6 1.1 1.7 -2.1 2.7 -0.7 1.6 1.1 0.3 -2.1 1.4 1.2 1.9 1.7 -2.0 0.9 0.8 2.0 -1.6 -0.7 -0.6 1.3 1.0 0.8 0.7 0.9 1.9 2.0 1.2 2.2 -0.3 0.6 0.5 1.3 1.2 1.4 2.3 0.5 0.9 1.1 2.3
Hair/balding pattern: Pattern 2 1.8 2.3 5.5 2.2 2.1 0.5 1.6 1.6 1.8 1.4 -1.3 0.8 1.2 1.6 2.0 1.4 0.7 0.8 1.7 1.4 0.2 0.6 1.5 -2.1 0.3 -1.6 1.4 1.7 1.7 1.8 1.5 2.0 2.1 1.1 0.4 2.1 0.1 1.7 1.8 2.3 1.7 1.3 1.7 0.4 1.9 1.9 1.6 0.0
Had menopause 1.9 2.3 7.4 -1.6 -2.0 -0.7 -1.1 -1.2 -1.5 -0.9 -0.2 0.2 -1.3 -1.4 -2.0 -0.8 -2.1 -1.0 -1.6 -0.8 1.7 -2.0 -0.8 1.8 0.2 -0.1 -2.7 -2.5 -0.6 -0.4 -1.7 -1.8 -2.0 -0.5 -0.1 -1.6 1.5 -2.6 -1.7 -2.5 -1.6 -1.2 -1.6 0.3 -2.7 -1.7 -1.4 0.5
Had other major operations 0.5 0.6 2.3 -0.0 -1.1 1.3 -0.2 0.2 -0.9 0.2 1.0 -0.6 -1.0 0.2 -0.4 0.4 1.0 0.9 -0.1 0.1 -0.2 1.3 0.6 1.0 1.2 1.5 0.9 0.1 -0.3 -0.4 0.5 -1.2 -0.8 0.4 0.7 -1.1 0.2 0.3 -0.7 -0.8 -0.0 -0.5 -1.2 1.0 -0.2 -1.1 -0.8 0.7
Forced vital capacity (FVC) 0.3 1.1 9.4 -1.2 -0.6 -1.7 -1.5 -0.6 -0.9 -0.9 3.1 -0.5 1.1 -0.7 -0.6 -2.1 -0.4 -1.1 -0.5 -0.9 0.6 -0.5 -1.8 -0.6 -0.9 0.7 -1.0 -0.4 -1.4 -0.3 -0.8 -0.9 -0.6 -0.9 -1.0 -0.5 -1.2 -0.8 -0.9 -0.5 -0.7 -1.3 -0.2 -0.7 -1.0 -1.0 -1.0 -0.8
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.6 3.5 -0.9 0.4 -0.6 -0.6 -0.6 0.2 -0.6 1.4 -1.2 1.1 -0.6 -0.2 -0.0 1.9 -0.4 -0.4 -0.4 -0.4 1.7 -0.1 -0.7 -1.0 0.8 1.0 0.9 -0.1 0.8 0.0 0.3 -0.1 -0.8 -0.8 -0.3 -1.2 0.8 0.1 0.1 -0.4 -0.1 -0.5 -1.2 0.2 0.2 -0.0 -1.1
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 1.3 -0.4 0.0 -0.8 -0.3 -0.7 -0.1 -0.6 0.8 0.1 0.0 -0.7 -0.5 -1.1 -0.1 -0.4 -0.5 -0.6 -0.3 -0.1 -0.1 -0.1 -0.8 -1.0 -0.4 0.2 -0.9 -0.6 -0.1 -0.1 -0.5 -0.5 -0.7 -0.3 -0.8 -0.5 0.0 -0.5 -0.6 -0.1 0.1 -0.7 -0.5 -0.1 -0.2 -0.7
Qualifications: None of the above 3.2 6.9 12.9 -3.2 -1.6 -2.1 -3.0 -3.3 -2.6 -3.1 -1.6 -2.8 -1.6 -3.1 -2.9 -1.2 3.1 -2.3 -3.2 -3.1 -3.6 3.2 -2.3 2.2 -2.7 3.2 0.3 -0.9 -2.8 -2.6 -1.6 -2.1 -2.8 -3.0 -2.8 -3.1 -3.2 -0.6 -2.0 -2.6 -2.9 -2.7 -3.2 -3.1 -2.4 -2.3 -2.6 -3.0
Financial difficulties in last 2 years 0.4 0.6 1.5 -0.2 -0.8 -1.2 -0.8 -0.6 -0.9 -0.7 1.0 -0.6 0.6 -0.7 -0.6 -1.1 -1.0 -1.1 -0.6 -0.8 -0.8 -1.0 -0.6 0.2 -0.6 0.2 -1.1 -0.9 -1.1 -0.8 -1.2 -0.8 -0.5 -0.7 -0.7 -0.5 0.0 -1.0 -0.7 -0.3 -0.7 -0.7 -0.4 -0.5 -0.5 -0.8 -0.8 -0.5
Mouth/teeth dental problems 1.7 2.6 5.9 1.7 1.2 1.0 1.9 1.8 1.5 2.0 -0.1 1.6 0.9 1.8 1.6 0.2 -2.4 1.2 1.8 1.8 1.5 -2.3 1.1 -0.8 1.9 -2.3 -0.6 0.2 1.3 1.5 1.4 1.5 1.5 2.2 1.9 2.0 1.9 -0.1 1.4 1.0 1.7 1.7 2.3 2.3 0.7 1.6 1.8 2.1
Heart attack 1.4 1.7 11.8 -1.3 -0.7 -1.0 -0.8 -1.6 -1.4 -1.4 -3.4 -1.2 -2.8 -1.6 -1.4 -1.2 -0.5 -1.6 -1.5 -1.4 -1.1 -0.3 -1.0 0.7 -1.4 -0.1 -1.2 -1.6 -0.8 -0.2 -1.3 -0.8 -1.3 -1.3 -1.4 -1.1 -1.1 -1.3 -0.8 -1.2 -1.5 -1.0 -0.6 -1.4 -1.4 -0.9 -1.0 -1.3
Allergy 0.4 1.0 2.5 -1.4 -0.6 -0.9 -1.4 -0.9 -0.6 -1.3 1.6 -0.9 0.7 -0.9 -0.7 -0.6 0.9 -0.9 -1.1 -0.9 -0.8 0.8 -1.4 0.0 -1.4 1.5 -0.0 0.1 -0.9 -0.6 -1.0 -0.7 -0.7 -1.4 -1.4 -0.9 -1.1 -0.2 -0.9 -0.4 -0.9 -1.2 -1.1 -1.5 -0.3 -0.8 -1.0 -1.5
Pain all over the body in last month 1.0 1.0 5.4 -0.9 -0.5 -0.1 -1.1 -1.2 -0.8 -1.1 -2.3 -1.6 -1.1 -1.2 -1.0 0.6 1.9 -0.5 -1.0 -1.2 -1.0 2.0 -0.2 0.9 -0.9 1.1 0.8 -0.9 0.5 -1.3 -0.5 -0.4 -1.0 -1.0 -0.6 -1.3 -0.8 0.3 -0.3 -0.9 -1.0 -0.1 -1.4 -1.2 -0.2 -0.4 -0.5 -0.9
Diabetes (self-reported) 0.4 0.7 4.3 1.1 1.2 -0.6 0.5 0.4 0.7 0.4 -2.1 0.2 -0.9 0.5 0.8 -0.4 -0.3 -0.1 0.6 0.4 -0.0 -0.4 -0.1 -1.6 -0.2 -1.6 -0.0 1.0 1.0 1.1 0.4 1.0 0.9 0.3 -0.1 1.2 -0.5 0.4 1.0 1.0 0.6 0.6 1.4 -0.2 0.5 1.0 0.8 -0.2
Hayfever/allergic rhinitis (self-reported) 0.1 0.2 2.0 0.1 -0.3 0.6 0.4 -0.1 -0.1 0.1 -1.1 1.4 -1.4 0.0 -0.2 0.2 -0.3 0.3 0.1 0.1 0.2 -0.1 0.5 0.6 0.3 -0.8 -0.1 -0.0 -0.2 0.0 0.2 -0.2 -0.3 0.2 0.2 -0.3 0.1 -0.4 -0.1 -0.4 -0.1 0.1 0.1 0.3 -0.1 -0.2 -0.1 0.3
Medication: Ramipril 4.0 5.1 9.8 2.3 3.0 2.2 2.7 2.1 2.6 2.5 -2.3 1.0 1.3 2.1 2.4 2.8 -0.0 2.0 2.6 2.3 0.8 -0.1 2.5 -1.8 1.8 -0.4 1.5 0.8 2.9 1.1 2.1 3.0 2.8 2.4 2.3 3.0 1.5 2.3 3.1 2.5 2.4 3.1 2.8 1.6 1.8 3.1 3.1 2.1
Medication: Simvastatin 0.6 0.8 6.2 0.8 0.2 0.3 0.4 0.3 0.5 0.4 -0.1 2.1 -0.5 0.4 0.4 -1.5 -2.2 0.1 0.0 0.5 -0.7 -2.5 -0.2 -1.8 0.1 -2.2 -1.5 0.1 -0.2 -0.1 -0.3 0.4 0.5 0.3 0.3 1.0 0.2 -0.7 0.1 0.4 0.3 0.2 1.6 0.4 -0.3 0.4 0.5 0.7
Fluid intelligence score 2.7 5.6 14.9 2.4 2.1 2.4 2.7 2.7 2.9 2.7 2.1 2.9 3.9 2.8 2.7 1.0 -0.5 2.7 2.7 3.0 1.5 -0.7 2.0 -1.3 2.3 -1.8 1.5 2.0 1.9 1.2 2.6 2.3 2.6 2.7 2.5 2.7 1.7 1.8 2.4 2.3 2.7 2.6 2.8 2.4 2.2 2.4 2.5 2.5
Illnesses of siblings 0.4 0.5 3.5 0.2 -0.4 -1.4 -0.3 -0.1 -0.5 -0.5 1.9 -0.6 1.2 -0.3 -0.3 -0.2 -1.1 -0.9 -0.1 -0.6 1.3 -1.3 -0.6 -0.4 -0.8 -0.6 -1.1 0.2 -0.8 -0.4 -1.2 -0.5 -0.1 -0.8 -0.7 0.0 -0.3 -0.6 -0.7 0.2 -0.4 -0.8 -0.0 -0.7 -0.2 -0.5 -0.5 -0.6
Neuroticism score 3.7 7.7 13.3 3.4 3.1 3.0 3.2 2.8 3.4 3.2 -1.4 2.9 0.4 2.9 3.0 3.3 -0.2 3.0 3.1 3.1 0.9 -0.3 3.0 -1.7 2.6 -2.6 1.7 1.4 3.1 0.9 2.9 3.3 3.2 3.2 3.1 3.3 2.3 2.4 3.4 2.7 3.1 3.7 3.2 2.5 2.3 3.4 3.5 3.0
Weight 1.2 6.0 14.6 -3.1 -3.1 -1.3 -2.6 -2.5 -3.0 -2.4 0.3 -2.7 -0.4 -2.7 -3.2 -1.2 0.9 -1.6 -2.8 -2.2 -0.4 1.1 -1.5 3.0 -1.0 3.5 -0.8 -3.3 -1.8 -3.4 -2.2 -3.2 -3.3 -2.2 -1.3 -3.6 -0.9 -1.7 -3.0 -3.3 -2.8 -2.7 -3.8 -1.3 -2.9 -3.1 -2.9 -1.1
Impedance of arm (right) 2.2 10.5 16.8 -3.1 -3.1 -3.4 -3.4 -3.5 -3.7 -3.7 -1.2 -3.2 -4.0 -3.4 -3.4 -3.4 -1.4 -4.1 -3.7 -3.8 -2.9 -1.2 -3.9 0.1 -3.4 2.6 -3.5 -1.9 -3.9 -0.8 -3.7 -3.2 -3.4 -3.7 -3.8 -3.1 -2.0 -3.7 -3.6 -3.0 -3.6 -4.1 -2.7 -3.0 -3.3 -3.3 -3.6 -3.4
Arm fat percentage (right) 0.5 2.1 5.4 -1.4 -2.3 -0.0 -1.2 -1.3 -1.6 -1.3 1.6 -0.6 0.1 -1.5 -1.9 -0.7 -0.4 -0.7 -1.6 -0.9 0.2 -0.4 -0.1 1.2 -0.3 1.7 -1.1 -1.5 -1.8 -2.1 -1.4 -2.1 -2.0 -1.2 -0.6 -2.1 0.4 -1.6 -2.2 -2.1 -1.7 -1.7 -2.3 -0.3 -1.9 -2.0 -1.9 -0.2
Trunk fat-free mass 1.1 6.3 15.0 -3.3 -3.0 -1.5 -2.9 -2.5 -3.2 -2.4 -0.9 -2.9 -0.7 -2.7 -3.2 -1.3 1.1 -1.6 -2.7 -2.4 -0.2 1.4 -2.2 3.8 -0.9 3.1 -0.8 -3.9 -1.0 -3.7 -2.3 -3.1 -3.3 -2.1 -1.2 -3.6 -1.1 -1.5 -2.7 -3.4 -2.8 -2.4 -3.7 -1.3 -2.8 -3.0 -2.8 -1.0
Hip circumference 0.3 1.3 9.6 -0.5 -1.7 1.0 -0.3 0.0 -0.6 0.0 3.1 0.5 1.6 -0.1 -0.9 0.3 0.1 1.0 -0.3 0.5 1.4 0.2 0.9 1.8 1.3 1.3 0.1 -0.7 -0.6 -2.3 -0.2 -1.6 -1.1 0.2 1.0 -1.4 1.0 -0.4 -1.3 -1.4 -0.4 -0.8 -1.7 1.1 -1.1 -1.4 -1.0 1.3
Time employed in main current job 0.6 0.7 7.6 -0.4 -1.2 0.3 0.1 -0.4 -0.9 -0.3 -2.8 0.3 -1.4 -0.5 -0.9 0.7 -0.7 -0.1 -0.8 -0.1 0.5 -0.7 -0.1 1.4 0.3 0.3 -1.0 -0.8 -0.1 0.3 -0.6 -0.9 -0.9 -0.3 0.1 -0.8 0.9 -1.0 -1.1 -1.0 -0.7 -0.6 -1.1 0.2 -0.9 -0.9 -0.7 0.4
Alcohol intake versus 10 years previously 2.3 3.5 9.7 -1.4 -0.7 -1.9 -2.2 -2.0 -1.9 -2.3 -1.5 -2.2 -3.1 -2.1 -1.6 -2.5 -0.1 -2.9 -1.9 -2.7 -0.6 -0.3 -2.2 -0.9 -2.8 0.3 -1.6 0.1 -1.4 1.4 -1.9 -0.9 -1.4 -2.5 -2.9 -1.2 -2.4 -1.5 -1.4 -1.0 -2.0 -2.2 -0.7 -2.7 -1.6 -1.1 -1.5 -2.9
Father’s age at death 0.3 0.4 2.7 -0.4 -0.8 -0.5 -0.7 -0.4 -0.7 -0.2 -0.0 -0.5 -0.4 -0.4 -0.7 -0.6 -0.7 -0.5 -0.6 -0.3 -0.7 -0.7 -0.6 1.6 0.2 0.9 -0.9 -1.1 -0.8 -1.1 -0.8 -0.8 -0.7 -0.2 0.1 -0.6 0.4 -0.8 -0.7 -0.8 -0.5 -0.4 -0.6 0.2 -0.7 -0.7 -0.6 0.3
Worrier / anxious feelings 1.6 3.0 7.9 2.1 1.9 1.8 1.8 1.4 2.3 1.9 -0.9 2.1 -0.0 1.6 1.7 1.2 -0.1 2.0 1.6 1.8 -0.1 -0.1 1.8 0.1 1.7 -1.6 1.2 0.5 1.8 0.2 1.8 2.4 1.7 2.1 2.3 1.9 1.2 1.5 2.3 1.2 1.8 2.8 2.1 1.6 1.2 2.5 2.6 2.2
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 3.9 1.6 0.5 0.6 1.1 1.0 0.9 1.2 -0.4 0.9 0.3 1.0 0.8 0.1 -1.9 0.5 1.0 1.0 0.6 -1.9 1.0 -0.1 1.2 -1.6 -0.8 -0.9 0.4 0.7 0.4 0.9 0.8 1.3 1.3 1.1 2.0 -0.4 0.9 0.5 0.9 1.4 1.3 1.4 0.6 1.0 1.1 1.5
Falls in the last year 0.8 1.1 4.1 -1.3 -0.9 -0.1 -1.5 -1.3 -0.7 -1.0 2.0 -0.2 -0.4 -1.5 -1.5 -0.6 -0.8 -0.7 -1.0 -1.1 1.4 -0.5 -0.6 1.3 -0.5 -0.1 -1.2 -0.9 -1.0 -1.0 -1.7 -0.6 -1.4 -0.8 -0.3 -1.2 0.3 -1.2 -0.6 -1.7 -1.4 -0.2 -1.1 -0.7 -1.6 -0.6 -0.5 -0.0
Hair/balding pattern: Pattern 3 2.4 3.6 6.2 2.0 1.4 2.3 2.5 2.3 1.9 2.3 0.6 2.0 -0.4 2.3 2.1 1.6 -0.4 2.5 2.3 2.1 2.1 -0.5 2.3 -1.6 2.2 -1.2 1.2 1.8 1.7 1.0 2.2 1.6 1.9 2.3 2.4 2.0 1.5 1.4 1.7 1.6 2.2 2.1 2.1 2.3 1.7 1.8 2.0 2.3
Number of live births 6.0 8.5 13.5 -3.4 -2.1 -3.6 -3.6 -3.5 -3.0 -3.7 1.0 -2.9 -1.3 -3.5 -3.2 -3.5 -0.0 -3.5 -3.4 -3.5 -2.6 -0.2 -3.4 0.9 -3.5 1.2 -2.3 -1.5 -2.8 -1.4 -3.5 -2.7 -3.0 -3.6 -3.6 -2.8 -3.0 -2.4 -2.6 -2.6 -3.4 -3.4 -2.6 -3.5 -3.2 -2.8 -3.1 -3.4
Forced expiratory volume in 1-second (FEV1) 0.6 2.2 7.0 -1.8 -0.0 -2.6 -2.2 -1.5 -1.0 -1.7 1.7 -1.4 1.2 -1.5 -0.9 -2.4 0.2 -2.2 -1.1 -1.8 -0.5 0.1 -2.6 -1.0 -2.3 0.7 -0.9 -0.7 -1.4 0.1 -1.4 -0.4 -0.7 -1.9 -2.1 -0.5 -2.6 -0.6 -0.6 -0.4 -1.3 -1.5 -0.1 -2.2 -1.2 -0.6 -0.9 -2.2
Pulse rate 0.6 1.0 16.4 0.7 -0.5 -0.3 0.7 0.6 -0.7 0.2 -4.0 -1.7 -1.7 0.5 0.4 0.8 -0.3 -0.4 0.3 -0.2 1.5 -0.3 0.2 1.7 0.3 1.0 -0.1 -2.3 1.4 1.8 0.3 -0.3 -0.0 0.3 0.1 -0.2 1.4 -0.5 -0.2 0.2 0.4 0.3 -0.2 0.5 1.2 -0.3 -0.3 0.2
Happiness 0.7 0.9 3.3 1.3 0.7 0.3 1.4 1.1 0.7 1.1 -1.3 0.6 0.8 1.0 1.0 0.8 -0.5 0.7 1.2 1.0 1.8 -0.5 1.6 0.1 0.9 -0.8 0.3 0.2 1.1 0.9 0.9 0.8 0.9 1.1 0.8 1.0 0.7 0.4 0.9 0.9 1.0 1.0 1.1 1.0 0.9 0.8 0.9 0.8
Noisy workplace 0.5 0.6 4.7 -0.2 -0.1 0.9 -0.1 -0.4 -0.0 -0.2 -1.5 0.5 -2.1 -0.4 -0.4 1.4 1.4 0.5 -0.3 -0.2 0.7 1.5 0.6 2.2 0.2 0.3 0.9 0.2 0.8 -0.9 0.3 0.1 -0.4 0.0 0.4 -0.7 0.2 0.5 0.2 -0.6 -0.3 0.6 -0.9 -0.1 -0.0 0.1 0.1 0.2
Qualifications: A levels/AS levels or equivalent 0.5 1.0 2.5 1.0 1.2 0.9 0.5 1.0 1.2 1.1 0.5 1.3 1.3 1.0 1.1 0.6 -0.6 0.9 1.2 0.9 1.3 -0.5 0.5 -0.0 0.8 -0.5 0.4 0.6 1.2 -0.0 0.5 1.4 1.2 1.1 1.2 1.3 1.0 0.7 1.3 0.9 1.1 1.6 1.3 0.8 0.9 1.4 1.5 1.2
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.4 2.9 -0.5 0.9 -1.0 -0.3 -0.6 0.4 -0.3 -1.7 -0.2 0.7 -0.6 -0.1 -0.6 0.5 -0.8 -0.1 -0.4 -0.1 0.5 0.1 0.7 -0.8 -0.5 0.1 -1.4 0.7 -0.8 0.2 0.9 0.0 -0.3 -0.5 0.2 -0.8 0.1 0.7 -0.0 -0.3 0.6 0.5 -0.9 -0.1 0.8 0.6 -0.8
Mouth/teeth dental problems: Dentures 0.7 1.2 5.7 -0.7 -0.8 -0.3 -0.6 -0.9 -1.2 -1.0 -2.1 -1.9 -0.7 -0.9 -0.9 0.5 1.6 -0.7 -1.1 -1.0 -2.4 1.4 -0.5 0.8 -0.7 2.2 0.5 -0.8 -0.9 -1.5 -0.6 -1.0 -0.8 -1.1 -0.8 -1.2 -0.7 0.2 -0.8 -0.5 -0.9 -0.8 -1.5 -1.0 -0.3 -1.0 -1.1 -0.9
Asthma 1.3 2.5 5.7 1.7 2.1 1.3 2.0 1.3 2.0 1.7 -0.3 1.3 0.3 1.4 1.5 2.1 1.1 1.8 1.7 1.6 0.5 1.2 2.4 -1.5 1.2 -1.7 1.8 1.6 1.9 0.5 2.1 2.0 1.7 1.6 1.4 1.7 0.1 2.0 2.1 1.5 1.6 1.8 1.6 1.0 1.1 2.0 1.9 1.0
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 3.8 -0.0 0.8 -0.1 0.3 0.3 1.0 0.7 -0.7 0.6 1.9 0.4 0.4 0.7 0.0 0.2 0.5 0.7 0.1 0.2 0.4 0.2 0.5 -1.0 0.2 -0.5 1.0 0.2 0.7 1.0 0.5 0.7 0.6 0.7 0.7 0.4 0.7 0.2 0.4 0.7 0.5 0.5 -0.0 1.0 0.9 0.5
Medication: Cholesterol lowering 0.5 0.8 6.9 0.6 0.5 0.1 0.6 0.0 0.6 0.3 -2.0 1.6 -0.3 0.2 0.3 -1.0 -1.6 -0.1 0.1 0.6 -1.1 -1.9 0.3 -1.9 0.0 -2.6 -1.2 -0.4 0.4 0.3 -0.0 0.6 0.5 0.3 0.2 1.0 -0.2 -0.4 0.4 0.3 0.2 0.4 1.5 0.2 -0.5 0.6 0.6 0.4
Depression (self-reported) 5.0 6.0 11.7 3.0 1.9 2.2 2.9 2.8 3.0 3.1 0.9 3.1 2.8 2.9 2.5 1.7 -0.5 3.1 2.8 3.4 1.0 -0.7 2.8 -0.1 3.1 -1.8 1.3 1.0 1.8 0.7 3.0 2.2 2.5 3.3 3.2 2.6 2.5 1.7 2.4 1.9 2.8 2.8 2.5 3.2 1.8 2.4 2.6 3.2
Medication: Lansoprazole 2.5 2.8 17.9 0.0 2.3 1.9 0.9 0.5 1.5 0.8 0.3 -0.3 1.4 0.7 1.2 2.4 3.2 1.9 1.1 0.6 -1.7 3.2 1.1 -2.7 0.3 0.9 3.2 4.2 1.0 -0.6 1.8 1.8 1.4 0.7 0.7 1.2 -1.3 3.1 2.0 1.4 1.1 1.2 0.5 -0.3 0.8 1.7 1.5 0.0
Prospective memory result 1.4 1.7 5.2 -1.4 -1.2 -1.0 -1.1 -1.7 -1.5 -1.4 -0.1 -0.9 -1.2 -1.7 -1.9 -1.2 -0.6 -1.2 -1.7 -1.6 -0.9 -0.5 -1.4 1.5 -0.8 1.1 -1.4 -0.8 -2.0 -1.3 -1.6 -1.3 -1.7 -1.0 -0.8 -1.5 -0.8 -1.4 -1.1 -2.0 -1.7 -1.1 -1.3 -0.8 -2.3 -1.3 -1.2 -0.6
Lung cancer (father) 2.2 2.6 6.2 -1.6 -1.8 -0.5 -1.5 -1.7 -2.2 -1.8 -0.5 -1.7 -2.4 -1.7 -1.8 -0.1 1.1 -1.0 -1.9 -2.0 -1.1 1.2 -1.3 1.0 -1.3 2.5 -0.2 0.2 -1.9 -1.4 -1.5 -2.0 -1.9 -1.9 -1.4 -2.1 -1.3 -0.8 -1.9 -1.6 -1.8 -2.0 -2.2 -1.5 -1.4 -2.0 -2.0 -1.4
Illnesses of mother 0.6 0.7 3.6 -0.1 0.6 -0.8 -0.8 -0.2 -0.1 -0.7 0.6 -0.5 0.9 -0.3 0.2 -0.8 0.9 -1.0 -0.1 -0.5 0.3 0.7 -0.9 -1.5 -1.5 0.3 0.3 1.3 -0.1 0.7 -0.4 0.0 0.5 -1.1 -1.5 0.3 -1.9 0.7 0.1 1.0 -0.2 -0.9 0.2 -1.5 0.4 -0.1 -0.4 -1.8
Forced expiratory volume in 1-second (FEV1), Best measure 1.3 4.1 14.3 -2.5 -1.0 -3.1 -2.8 -2.2 -1.8 -2.5 0.7 -1.8 0.1 -2.3 -1.8 -3.1 -0.4 -3.0 -2.0 -2.7 -0.4 -0.4 -3.8 -0.3 -3.0 0.6 -1.8 -1.8 -1.8 0.4 -2.5 -1.2 -1.6 -2.7 -2.8 -1.4 -2.4 -1.7 -1.5 -1.1 -2.1 -2.1 -0.9 -2.8 -1.6 -1.3 -1.6 -2.7
Pulse wave Arterial Stiffness index 0.2 0.3 1.2 -0.6 -0.8 0.1 -0.6 -0.3 -0.7 -0.4 0.7 -0.4 -0.5 -0.3 -0.5 -0.3 -0.2 0.1 -0.5 -0.4 -0.3 -0.1 -0.4 -0.1 -0.0 1.1 -0.3 0.2 -0.7 -0.2 -0.5 -0.9 -0.6 -0.3 -0.2 -0.6 -0.1 -0.5 -0.8 -0.6 -0.4 -0.8 -0.7 0.0 -0.6 -0.8 -0.8 0.0
Impedance of arm (left) 1.5 6.9 13.2 -2.3 -2.4 -2.8 -2.7 -2.7 -2.9 -2.9 -0.4 -2.8 -3.1 -2.6 -2.6 -2.5 -0.7 -3.3 -2.9 -3.1 -3.0 -0.7 -2.9 -0.2 -2.9 2.6 -2.5 -1.1 -3.6 -0.8 -2.8 -2.6 -2.6 -3.1 -3.3 -2.5 -1.8 -2.8 -3.1 -2.1 -2.8 -3.5 -2.2 -2.6 -2.3 -2.8 -3.1 -3.0
Arm fat mass (right) 0.8 3.3 8.8 -2.2 -2.5 -0.4 -1.8 -1.8 -2.1 -1.8 1.0 -1.4 -0.0 -2.0 -2.5 -0.8 0.4 -1.0 -2.1 -1.4 -0.1 0.5 -0.7 1.9 -0.6 2.5 -0.8 -2.1 -1.7 -2.8 -1.7 -2.5 -2.5 -1.6 -0.9 -2.7 -0.3 -1.4 -2.4 -2.5 -2.2 -2.1 -3.0 -0.9 -2.3 -2.4 -2.2 -0.6
Trunk predicted mass 1.1 6.2 14.7 -3.3 -3.0 -1.5 -2.9 -2.5 -3.2 -2.4 -0.8 -2.8 -0.6 -2.7 -3.2 -1.2 1.1 -1.6 -2.7 -2.4 -0.3 1.4 -2.2 3.8 -0.9 3.1 -0.7 -3.8 -1.0 -3.8 -2.3 -3.1 -3.3 -2.1 -1.2 -3.6 -1.1 -1.5 -2.7 -3.3 -2.8 -2.4 -3.7 -1.3 -2.8 -3.0 -2.8 -1.0
Standing height 3.8 37.4 59.4 -7.4 -6.4 -5.6 -7.2 -6.7 -7.7 -6.7 -3.5 -7.6 -5.6 -6.9 -7.2 -4.6 0.8 -6.2 -7.0 -7.1 -3.4 1.4 -6.6 5.7 -4.7 6.8 -3.8 -7.1 -4.6 -5.0 -6.2 -6.8 -7.4 -6.2 -5.3 -7.6 -3.9 -5.0 -6.7 -7.0 -7.0 -6.8 -7.3 -4.8 -6.5 -6.8 -6.9 -4.7
Length of working week for main job 1.4 1.6 7.7 -1.3 -0.5 -0.3 -1.1 -1.0 -1.0 -1.0 -2.3 -2.8 -1.1 -1.0 -0.9 0.9 2.5 -0.4 -0.8 -1.1 -0.2 2.6 -0.4 2.6 -0.8 2.4 1.4 -1.5 0.8 -0.6 -0.3 -0.6 -1.0 -1.0 -0.7 -1.5 -0.7 0.6 -0.3 -0.7 -0.8 -0.2 -1.8 -1.2 0.3 -0.7 -0.7 -0.9
Exposure to tobacco smoke at home 0.8 0.9 2.8 -0.9 -0.8 -1.0 -0.7 -1.2 -1.0 -1.0 -1.5 -0.8 -1.4 -1.2 -1.2 -0.3 0.2 -1.2 -1.0 -1.1 -0.7 0.1 -1.0 1.7 -0.8 0.6 -0.7 -1.4 -0.6 -0.4 -0.9 -0.8 -1.1 -0.9 -0.9 -1.1 -0.5 -0.8 -0.7 -1.1 -1.1 -0.7 -1.0 -0.9 -0.9 -0.8 -0.8 -0.9
Breastfed as a baby 0.5 0.6 1.7 -1.3 -0.8 -1.0 -0.5 -0.9 -0.7 -0.8 0.3 -0.6 -0.3 -1.0 -1.1 -0.2 -0.5 -0.8 -0.9 -0.7 0.9 -0.3 -0.6 0.7 -0.4 0.4 -1.0 -0.7 -0.9 0.3 -0.9 -0.7 -1.1 -0.6 -0.5 -0.9 -0.0 -1.0 -0.8 -1.2 -1.0 -0.8 -0.9 -0.4 -1.3 -0.7 -0.7 -0.5
Tense / ‘highly strung’ 3.8 6.3 14.4 2.5 3.8 2.4 2.4 2.1 3.4 2.3 -1.4 2.6 0.8 2.3 2.9 2.8 1.0 2.5 2.7 2.3 0.1 1.0 2.4 -2.7 1.0 -2.3 2.5 2.4 3.2 1.1 2.5 3.6 3.2 2.1 1.7 3.3 -0.0 3.1 3.7 3.0 2.7 3.0 3.2 0.8 2.5 3.5 3.4 1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 3.3 5.0 9.3 2.6 2.5 2.0 2.4 2.2 3.0 2.5 1.1 2.8 2.4 2.3 2.4 1.7 -0.9 2.2 2.5 2.6 0.8 -0.9 2.5 -1.3 1.8 -2.9 1.0 1.1 2.0 0.9 2.0 2.8 2.6 2.5 2.3 2.9 2.0 1.5 2.8 2.2 2.4 2.9 2.8 1.9 1.9 2.9 2.9 2.2
Hair/balding pattern: Pattern 4 0.5 1.2 4.9 -0.9 -1.2 -0.5 -1.4 -1.0 -1.2 -1.0 1.6 -1.1 0.5 -1.1 -1.2 0.7 1.6 -0.4 -1.1 -0.9 -1.2 1.6 -0.6 0.8 -0.5 1.8 0.3 -0.4 -1.4 -1.4 -0.8 -1.4 -1.2 -1.0 -0.7 -1.6 0.0 -0.1 -1.1 -1.0 -1.1 -1.0 -2.2 -0.8 -0.7 -1.4 -1.4 -0.7
Birth weight of first child 0.9 1.5 10.5 1.3 0.6 -0.6 0.2 0.3 0.9 0.3 1.3 2.5 0.6 0.4 0.5 -2.7 -2.9 -0.6 0.5 0.5 0.2 -2.8 0.3 -1.5 -0.4 -3.2 -1.9 -0.1 -0.5 2.0 -0.4 0.8 0.7 0.4 -0.3 1.3 0.4 -1.4 0.6 0.6 0.3 0.3 1.9 0.2 -0.0 0.8 0.7 -0.1
Peak expiratory flow (PEF) 1.8 4.3 9.5 -2.4 -1.3 -3.1 -2.9 -2.2 -2.0 -2.6 1.5 -2.0 -0.2 -2.3 -1.8 -2.4 0.2 -3.0 -1.9 -2.6 -0.3 0.3 -2.8 0.2 -3.0 0.9 -1.4 -1.8 -2.1 0.1 -2.5 -1.6 -1.8 -2.8 -3.0 -1.8 -2.5 -1.5 -1.8 -1.2 -2.2 -2.4 -1.4 -2.9 -1.3 -1.8 -2.1 -3.0
Pulse wave reflection index 0.4 0.5 7.5 -0.2 0.4 0.8 0.0 0.4 0.7 0.4 2.7 1.0 1.2 0.4 0.3 -0.1 -0.2 0.8 0.3 0.6 0.2 -0.1 -0.2 -1.7 0.4 -0.6 0.3 1.8 -0.4 0.2 0.2 0.3 0.4 0.4 0.5 0.5 -0.1 0.5 0.3 0.3 0.4 0.0 0.4 0.4 -0.1 0.3 0.4 0.5
Ever highly irritable/argumentative for 2 days 0.3 0.3 2.0 0.6 -0.7 -1.0 0.2 0.2 -0.6 -0.3 -0.1 -0.9 -0.2 0.2 0.1 -0.3 -0.2 -0.5 0.1 -0.1 0.8 -0.4 0.5 0.9 -0.5 -0.3 -0.3 -0.9 -0.3 1.4 -0.4 -0.7 -0.2 -0.5 -0.8 -0.3 0.1 -0.5 -0.8 0.3 -0.1 -0.6 -0.3 -0.3 0.9 -0.8 -0.8 -0.7
Loud music exposure frequency 1.5 1.6 5.0 -1.6 -1.4 -0.7 -1.5 -1.3 -1.4 -1.5 -0.0 -0.4 -0.3 -1.2 -1.4 -0.2 0.8 -0.5 -1.5 -1.1 -1.6 0.8 -1.1 0.3 -1.1 1.3 -0.2 0.5 -1.7 -2.2 -1.4 -1.6 -1.5 -1.6 -1.1 -1.7 -1.3 -0.6 -1.6 -1.2 -1.4 -1.7 -1.9 -1.2 -1.0 -1.7 -1.6 -1.1
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 5.3 0.6 -0.6 0.2 0.2 0.6 -0.0 0.5 1.6 1.3 -0.0 0.4 0.1 -0.1 -1.8 0.3 0.5 0.5 2.3 -1.6 0.4 0.5 0.9 -0.9 -1.0 -0.1 0.2 0.7 -0.3 -0.3 0.0 0.6 0.8 0.2 1.2 -0.8 -0.4 -0.2 0.2 0.2 0.2 1.1 -0.1 -0.2 -0.0 1.1
Mouth/teeth dental problems: Bleeding gums 1.9 2.4 10.5 -2.0 0.4 -0.9 -1.9 -1.9 -0.3 -1.8 0.7 -1.1 -0.1 -1.6 -1.0 -0.8 3.0 -0.9 -1.2 -1.6 -2.8 3.0 -1.3 -1.3 -2.3 1.2 1.4 1.6 -1.0 -1.3 -0.6 -0.1 -0.8 -1.9 -2.0 -1.0 -3.2 0.9 -0.1 -0.5 -1.2 -1.1 -1.1 -2.7 -0.7 -0.3 -0.7 -2.5
Blood clot in the leg (DVT) 0.6 0.8 2.0 -1.4 -0.4 -0.8 -1.2 -1.4 -0.5 -1.0 -0.7 0.7 -0.6 -1.3 -1.2 -0.7 0.5 -0.6 -1.2 -0.9 -0.3 0.6 -0.9 1.2 -0.8 -1.1 -0.4 -0.7 -0.1 -1.4 -0.8 -0.4 -1.1 -0.9 -0.5 -1.0 -1.1 -0.5 -0.4 -1.3 -1.2 -0.4 -0.8 -1.0 -1.3 -0.4 -0.4 -0.5
Medication: Paracetamol 0.1 0.1 1.4 -0.5 0.2 0.0 0.1 -0.2 0.1 0.0 -0.9 -0.5 -0.1 -0.2 -0.2 0.4 0.1 -0.2 0.1 -0.1 0.7 0.4 0.4 0.7 0.1 -0.3 0.1 -1.2 0.5 0.2 0.4 0.2 -0.2 0.2 0.1 -0.1 0.1 -0.1 0.2 -0.5 -0.1 0.1 -0.1 0.2 -0.5 0.2 0.2 0.1
Headache pain in last month 0.7 1.2 5.5 0.9 1.5 -1.1 0.6 0.5 0.8 0.3 -2.3 -0.9 0.8 0.5 1.1 1.1 1.5 -0.5 0.8 0.1 0.3 1.5 0.8 -0.5 -0.8 -1.3 1.3 -0.4 1.9 1.9 0.9 1.4 1.2 -0.0 -0.5 1.0 -0.5 1.3 1.2 1.6 0.7 0.9 0.6 -0.8 1.8 1.2 0.9 -0.9
Medication for cholesterol, blood pressure or diabetes 1.3 2.2 4.5 -1.1 -1.7 -2.0 -2.1 -1.1 -1.9 -1.6 1.9 -2.0 -0.5 -1.3 -1.4 -1.4 -0.4 -1.9 -1.3 -1.9 0.7 -0.1 -1.9 1.7 -1.4 1.2 -1.1 -1.2 -1.5 -0.2 -1.7 -1.7 -1.5 -1.6 -1.7 -1.7 -0.4 -1.6 -1.7 -1.1 -1.4 -1.9 -1.7 -1.2 -0.7 -1.8 -1.9 -1.6
Glaucoma (self-reported) 0.2 0.3 2.4 -0.1 -0.0 -0.2 -0.3 -0.3 -0.1 -0.5 -1.5 0.6 -0.9 -0.4 -0.1 -0.3 0.1 -0.4 -0.4 -0.3 0.2 0.1 -0.3 -0.6 -0.9 -0.8 -0.1 -0.0 0.8 0.6 -0.4 -0.1 -0.0 -0.8 -0.8 -0.1 -0.6 -0.0 -0.1 0.3 -0.3 -0.3 -0.1 -1.0 0.4 -0.2 -0.3 -0.9
Gout (self-reported) 0.9 1.2 8.0 -1.0 1.1 0.7 0.0 -0.4 0.5 -0.2 -0.1 0.1 1.2 -0.2 0.2 0.6 2.8 0.5 -0.1 0.0 -1.7 2.6 -0.2 -1.7 -0.6 1.6 2.0 2.7 -0.6 -1.4 0.8 0.6 0.3 -0.4 -0.4 0.1 -2.2 1.8 0.7 0.4 0.1 -0.2 -0.0 -0.9 -0.1 0.5 0.3 -0.9
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 4.4 0.6 1.9 -0.2 0.6 0.4 1.4 0.3 -0.5 0.3 1.5 0.6 1.3 -0.7 0.3 0.2 0.9 0.6 -1.2 0.3 0.7 -2.1 -0.8 -0.7 1.0 0.3 1.2 0.9 0.5 1.7 1.5 0.0 -0.4 1.6 -1.7 1.2 1.5 1.8 0.9 0.8 1.9 -0.8 1.3 1.5 1.3 -0.8
Medication: Amlodipine 1.1 1.6 4.0 1.4 1.5 0.9 1.4 1.1 1.4 1.3 -0.7 -0.1 0.6 1.2 1.4 1.5 1.5 1.3 1.2 1.3 -1.2 1.5 1.7 -0.8 0.9 0.1 2.0 1.1 1.5 1.0 1.7 1.4 1.5 1.1 0.9 1.2 0.2 2.0 1.5 1.6 1.4 1.3 0.8 0.6 1.5 1.4 1.3 0.5
Medication: Ventolin 100micrograms inhaler 0.2 0.3 2.5 0.3 0.3 -0.7 -0.3 -0.3 -0.0 -0.4 0.5 0.3 -0.5 -0.2 0.0 -0.7 0.2 -0.5 -0.1 -0.3 -0.4 0.2 0.1 -0.7 -0.8 -1.6 -0.1 0.5 -0.1 1.1 0.1 0.1 0.1 -0.5 -0.8 0.2 -1.3 0.1 -0.0 0.3 -0.1 -0.6 0.4 -0.7 -0.1 -0.0 -0.2 -1.0
Birth weight 0.5 1.1 4.2 -0.8 -0.8 -0.0 -1.4 -1.2 -0.8 -1.0 -0.6 1.2 -1.3 -1.2 -1.3 -1.9 -1.3 -0.7 -1.2 -0.9 -0.2 -1.1 -1.3 1.3 -0.6 -0.9 -1.4 -1.2 -0.9 -2.0 -1.6 -0.7 -1.2 -0.8 -0.4 -0.9 -0.6 -1.3 -0.6 -1.4 -1.1 -0.5 -0.4 -0.6 -1.4 -0.7 -0.5 -0.2
Chronic bronchitis/emphysema (mother) 0.3 0.4 2.1 -0.0 0.7 0.6 0.4 -0.1 0.8 0.4 0.2 0.8 -1.5 -0.0 0.0 0.5 0.2 0.6 0.2 0.3 0.5 0.4 0.5 0.4 0.5 -1.2 0.3 0.4 0.8 -0.4 0.6 0.9 0.1 0.7 0.7 0.3 0.3 0.3 1.0 -0.3 0.2 1.1 0.5 0.4 -0.2 0.9 1.0 0.6
High blood pressure (siblings) 0.9 1.3 3.8 0.3 1.1 1.9 1.1 1.0 1.2 1.3 -0.8 0.7 -0.0 1.1 1.1 0.9 1.1 1.9 1.0 1.2 -0.2 1.2 0.4 -0.7 1.5 0.6 1.8 1.2 1.4 -0.1 1.7 1.1 1.0 1.5 1.6 0.8 0.4 1.5 1.4 0.6 1.3 1.5 0.8 1.3 0.8 1.2 1.3 1.4
Forced vital capacity (FVC), Best measure 0.7 2.6 7.8 -1.9 -1.7 -2.2 -2.1 -1.4 -1.8 -1.7 1.6 -1.0 -0.1 -1.6 -1.6 -2.6 -1.1 -2.0 -1.6 -1.7 0.4 -1.1 -2.8 0.4 -1.5 0.7 -2.0 -1.9 -1.6 -0.4 -1.9 -1.7 -1.6 -1.7 -1.6 -1.5 -1.0 -1.9 -1.8 -1.4 -1.7 -1.9 -1.1 -1.3 -1.6 -1.7 -1.7 -1.2
Body fat percentage 0.8 3.0 7.5 -2.0 -2.0 -0.7 -1.7 -1.9 -2.0 -2.0 0.2 -2.0 -0.7 -2.0 -2.2 -0.8 0.6 -1.3 -2.1 -1.7 -0.9 0.6 -0.6 0.7 -1.4 2.7 -0.7 -1.2 -1.8 -1.7 -1.6 -2.1 -2.2 -2.0 -1.6 -2.3 -1.0 -1.3 -2.2 -2.1 -2.1 -2.2 -2.5 -1.5 -2.0 -2.1 -2.2 -1.4
Leg fat percentage (right) 0.3 0.9 2.2 -1.1 -0.8 -0.2 -0.8 -1.2 -0.9 -1.2 -0.5 -1.5 -0.6 -1.2 -1.1 -0.3 1.1 -0.8 -1.2 -1.0 -0.5 0.9 -0.2 0.3 -1.1 1.4 0.1 -0.9 -0.6 -0.7 -0.8 -0.8 -1.1 -1.3 -1.1 -1.2 -1.0 -0.2 -0.9 -0.8 -1.2 -1.0 -1.4 -1.4 -0.7 -0.9 -1.0 -1.2
Arm fat-free mass (right) 0.8 4.2 10.8 -2.9 -2.4 -1.0 -2.3 -2.0 -2.5 -1.9 -0.4 -2.7 0.3 -2.2 -2.6 -0.6 1.5 -1.1 -2.1 -1.9 -0.0 1.7 -1.2 3.3 -0.7 3.0 -0.0 -3.2 -0.6 -3.2 -1.6 -2.5 -2.6 -1.7 -0.9 -3.0 -1.1 -0.8 -2.1 -2.7 -2.2 -1.9 -3.2 -1.1 -2.2 -2.5 -2.3 -0.8
Exposure to tobacco smoke outside home 0.7 0.9 5.2 0.6 0.7 1.3 0.3 0.1 0.3 0.3 -0.9 -0.0 -1.4 0.0 0.2 2.3 2.0 0.9 0.2 0.1 -0.8 2.2 0.8 0.9 0.4 0.5 1.8 1.1 0.4 -2.0 0.8 0.5 0.5 0.3 0.7 0.1 -0.2 1.7 0.9 0.4 0.3 1.0 -0.2 -0.1 0.6 0.6 0.6 0.4
Comparative body size at age 10 1.1 2.9 12.6 0.1 -2.2 1.5 0.0 0.1 -0.3 0.6 3.2 2.5 2.4 0.0 -1.0 -0.3 -2.3 0.9 -0.3 1.0 0.2 -2.1 1.5 3.6 2.2 -0.6 -1.5 -3.2 -1.9 -2.6 -0.5 -1.5 -1.3 1.1 1.9 -1.3 3.2 -1.9 -1.2 -2.1 -0.4 0.3 -1.1 2.3 -1.1 -1.2 -0.6 2.5
Number of full brothers 1.4 1.7 7.5 -0.7 0.9 -1.6 -1.6 -1.4 -0.1 -1.6 0.6 -0.3 -0.3 -1.2 -0.3 -2.4 0.5 -1.8 -0.7 -1.6 -0.9 0.4 -1.0 -1.6 -2.7 -1.5 -0.3 0.8 -0.6 1.8 -0.7 0.6 -0.2 -1.7 -2.3 0.1 -2.7 -0.2 0.3 0.2 -0.8 -0.7 0.7 -2.6 -0.2 0.3 -0.1 -2.7
Worry too long after embarrassment 3.1 5.2 9.0 2.7 2.9 1.9 2.6 2.3 2.9 2.5 -1.0 2.4 1.1 2.4 2.7 2.1 0.4 2.2 2.5 2.6 0.8 0.4 2.0 -1.0 1.6 -2.3 2.0 1.8 3.0 1.1 2.3 2.8 2.9 2.2 2.1 2.9 0.9 2.5 3.0 2.8 2.6 2.9 2.7 1.4 2.5 2.9 2.9 1.7
Seen a psychiatrist for nerves, anxiety, tension or depression 1.2 1.5 3.8 1.6 1.8 1.2 1.3 0.9 1.9 1.1 -0.1 1.3 1.0 1.0 1.3 0.6 -0.1 1.1 1.1 1.1 -0.1 -0.1 1.4 -0.6 0.4 -1.9 0.9 0.6 1.4 0.2 0.9 1.9 1.5 1.0 1.0 1.7 0.4 1.1 1.8 1.3 1.2 1.9 1.8 0.4 1.2 1.9 1.9 0.8
Wheeze or whistling in the chest in last year 1.0 1.8 6.5 1.7 1.3 0.2 1.8 1.6 1.5 1.5 -0.3 1.1 0.8 1.6 1.6 0.7 -0.3 1.0 1.7 1.7 1.4 -0.3 1.9 -1.1 1.0 -2.2 0.6 0.3 1.8 2.5 1.7 1.4 1.6 1.4 0.9 1.6 0.7 0.8 1.2 1.5 1.5 1.1 1.6 1.2 1.4 1.3 1.2 0.7
Number of children fathered 3.1 3.5 9.6 1.2 2.0 1.5 2.4 2.0 1.8 1.9 -0.9 -0.7 -0.2 2.0 2.0 1.9 2.4 2.2 2.0 1.8 1.5 2.4 1.5 -0.2 1.8 1.0 3.1 1.9 2.4 1.9 2.9 1.9 1.8 2.0 1.8 1.4 -0.2 2.8 2.1 1.6 2.2 1.9 1.4 1.5 2.1 1.9 2.0 1.2
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 1.8 0.3 0.8 0.8 0.8 0.3 0.9 0.6 1.1 0.3 -0.1 0.4 0.5 0.3 1.0 1.0 0.5 0.4 -0.3 0.9 0.8 0.1 0.5 0.2 1.2 1.4 0.2 -0.1 0.9 0.9 0.6 0.6 0.7 0.5 -0.3 1.1 0.9 0.4 0.6 1.0 0.6 0.3 0.7 0.9 0.9 0.4
Age at first live birth 7.2 12.8 27.0 4.6 3.8 3.3 4.0 4.3 4.1 4.2 -1.5 3.0 1.0 4.4 4.7 1.3 -1.0 3.3 4.3 4.1 1.6 -1.2 2.9 -2.7 2.9 -2.8 2.1 2.0 4.0 4.0 3.5 4.1 4.7 3.8 3.2 4.8 1.6 3.0 3.9 4.7 4.5 4.0 5.2 3.0 4.3 4.2 4.3 2.9
Pulse wave peak to peak time 0.1 0.1 0.7 0.0 0.2 -0.6 0.0 -0.3 0.0 -0.2 -0.8 -0.2 0.2 -0.3 -0.1 -0.2 0.2 -0.7 -0.1 -0.2 0.0 0.1 -0.2 0.3 -0.4 -0.6 -0.1 -0.6 0.2 -0.1 -0.1 0.3 -0.0 -0.3 -0.4 0.0 -0.3 0.0 0.2 -0.0 -0.2 0.1 0.1 -0.5 -0.0 0.2 0.1 -0.5
Health satisfaction 1.0 1.3 3.6 1.1 1.4 0.4 1.8 1.1 1.3 1.0 -1.7 1.2 0.7 1.2 1.3 1.1 0.7 1.0 1.4 1.4 1.2 0.6 1.9 -0.3 0.6 -1.1 1.2 0.8 1.4 1.0 1.6 1.2 1.2 1.1 0.6 1.2 -0.4 1.2 1.3 1.1 1.2 0.9 1.3 0.7 0.9 1.1 1.1 0.3
Shortness of breath walking on level ground 0.2 0.3 3.1 0.5 -0.1 -0.2 0.3 0.3 0.2 0.3 0.2 0.7 1.1 0.3 0.2 -0.7 -1.2 -0.4 0.3 0.4 0.4 -1.2 0.2 0.7 0.2 -1.0 -0.8 -1.8 -0.3 -0.1 -0.2 -0.1 0.1 0.3 0.0 0.2 0.5 -0.7 -0.0 0.2 0.2 0.0 0.5 0.4 0.2 -0.1 -0.1 0.2
Qualifications: College or University degree 3.9 12.2 19.6 3.8 2.9 3.2 4.1 4.3 3.9 4.1 2.0 3.3 2.1 4.2 4.0 2.2 -1.1 4.0 4.4 4.3 4.4 -1.2 3.7 -2.0 3.6 -3.1 2.0 2.1 4.4 3.8 3.6 3.2 3.8 4.0 3.8 3.9 2.7 2.4 3.3 3.5 4.1 3.9 4.1 3.7 3.7 3.4 3.6 3.7
Eye problems/disorders: None of the above 0.4 0.5 3.6 -0.7 -1.0 -0.2 0.2 -0.4 -0.5 -0.2 1.9 0.4 0.7 -0.4 -0.7 0.5 -0.3 0.1 -0.4 0.0 0.1 -0.4 0.8 0.5 0.4 0.6 -0.6 -0.2 -1.5 -0.5 -0.1 -1.0 -0.8 -0.0 0.1 -0.8 0.6 -0.8 -1.0 -1.1 -0.6 -0.7 -0.9 0.5 -1.2 -0.9 -0.8 0.4
Mouth/teeth dental problems: Loose teeth 0.8 1.0 4.5 1.6 1.0 -0.1 0.9 1.2 0.9 0.8 0.5 0.4 0.1 1.3 1.4 -0.1 -0.9 0.0 1.3 0.8 -0.0 -1.0 0.9 -2.1 0.0 -1.5 -0.0 0.5 0.6 2.1 0.7 0.9 1.5 0.5 0.1 1.6 0.3 0.3 0.7 1.7 1.2 0.3 1.6 0.3 1.4 0.8 0.7 0.1
Emphysema/chronic bronchitis 0.2 0.2 2.8 -0.1 0.5 -0.3 -0.3 -0.5 0.4 -0.3 -0.1 0.5 0.9 -0.4 -0.1 -0.6 0.0 -0.7 -0.3 -0.4 -1.0 -0.0 -0.6 0.2 -0.7 -1.7 -0.1 -0.2 -0.0 0.4 -0.4 0.6 0.0 -0.3 -0.4 0.2 -0.1 -0.1 0.5 -0.0 -0.2 0.5 0.2 -0.7 0.0 0.6 0.5 -0.5
Medication for pain relief, constipation, heartburn 0.5 0.9 5.9 1.3 0.9 0.8 0.3 0.9 0.8 0.5 1.3 0.1 -0.0 1.0 1.3 0.1 1.3 0.9 0.8 0.4 -0.5 1.2 -0.0 -1.0 -0.1 0.5 1.7 2.4 0.2 0.5 0.6 0.9 1.1 0.2 0.1 0.8 -0.7 1.6 0.8 1.6 1.1 0.7 0.7 -0.2 2.1 0.8 0.7 -0.2
Neck or shoulder pain in last month 0.2 0.3 2.0 0.7 -0.6 -0.0 0.2 0.4 -0.3 0.1 0.1 1.0 -0.4 0.2 0.1 0.4 -1.0 -0.4 0.1 0.1 1.1 -1.0 0.8 -0.2 0.0 -1.4 -0.8 -0.5 -0.1 1.0 -0.5 -0.4 0.2 -0.1 -0.1 0.2 0.9 -0.6 -0.6 0.3 0.0 -0.4 -0.0 0.2 0.2 -0.4 -0.4 0.2
Medication: Blood pressure 4.4 7.7 14.2 2.3 3.0 3.7 3.4 2.5 3.4 3.1 -1.4 2.7 1.6 2.6 2.7 3.8 1.4 3.7 2.7 3.3 0.2 1.1 3.6 -1.9 2.8 -0.8 2.8 2.3 3.1 -0.0 3.2 3.0 3.0 3.1 3.3 2.9 1.5 3.4 3.3 2.5 2.9 3.6 2.5 2.3 2.1 3.2 3.3 3.0
Angina (self-reported) 2.4 3.2 6.5 -1.4 -1.8 -2.5 -0.9 -1.6 -2.1 -1.9 -1.3 -1.2 -0.9 -1.7 -1.7 -1.9 -1.7 -2.5 -1.9 -1.9 -0.7 -1.8 -1.9 -0.7 -1.9 0.4 -2.4 -1.8 -2.1 1.4 -2.5 -2.0 -1.5 -2.1 -2.2 -1.3 -0.7 -2.3 -2.1 -1.2 -1.9 -2.4 -1.3 -1.6 -1.7 -2.1 -2.2 -1.8
Migraine (self-reported) 0.7 0.9 4.6 0.3 1.6 0.6 0.6 0.3 1.1 0.5 -1.7 -0.2 0.7 0.5 0.8 0.9 1.1 0.5 0.5 0.7 -1.8 1.1 0.4 -2.1 -0.1 0.4 1.2 0.8 1.5 -0.2 0.7 1.1 1.1 0.3 0.1 1.1 -0.7 1.4 1.2 1.1 0.7 0.6 0.8 -0.3 0.6 1.1 0.9 -0.2
Medication: Ibuprofen 1.0 1.2 2.6 0.6 1.4 0.8 0.9 1.0 1.5 1.3 -0.5 0.7 1.5 1.0 1.1 1.6 0.4 0.9 1.1 1.2 0.1 0.5 0.9 0.2 1.1 -0.4 0.9 -0.2 1.5 0.2 1.2 1.5 1.2 1.3 1.3 1.3 0.8 1.2 1.3 0.9 1.1 1.3 1.0 1.0 0.6 1.5 1.5 1.1
Medication: Allopurinol 0.9 1.1 7.9 0.1 1.1 1.1 0.8 0.5 0.7 0.5 -0.5 0.3 1.4 0.7 0.9 1.4 2.1 1.2 0.6 0.8 -1.5 2.0 0.6 -1.6 0.2 1.0 2.0 2.8 0.2 -0.8 1.1 0.6 1.0 0.3 0.1 0.7 -1.2 1.9 0.8 1.2 0.8 0.1 0.3 -0.1 0.7 0.6 0.4 -0.3
Medication: Omeprazole 1.0 1.2 4.2 -0.6 -1.4 -0.8 -0.8 -1.0 -1.2 -1.1 2.0 -0.1 0.4 -1.1 -1.3 -0.8 -0.9 -0.9 -0.9 -0.7 0.3 -0.9 0.4 0.4 -0.7 -0.7 -1.2 -1.6 -1.3 -0.7 -1.6 -1.6 -1.2 -1.1 -0.9 -1.2 -0.3 -1.3 -1.4 -1.1 -1.2 -1.3 -1.1 -0.7 -1.2 -1.5 -1.5 -0.6
Medication: Seretide 50 evohaler 0.3 0.3 1.4 0.6 0.1 0.7 0.6 0.5 0.4 0.4 1.2 1.2 1.2 0.5 0.4 1.1 0.6 0.7 0.5 0.7 -0.2 0.5 0.9 -0.1 0.5 -0.4 0.7 0.5 0.1 -0.6 0.5 -0.0 0.4 0.4 0.4 0.2 0.2 0.6 0.2 0.5 0.5 0.1 0.0 0.4 0.5 0.0 0.1 0.3
Mean time to correctly identify matches 0.5 1.0 9.1 0.8 0.8 -0.2 1.7 1.1 0.5 0.9 -3.0 0.1 -0.4 1.0 1.0 0.4 -1.0 0.1 0.9 0.9 1.5 -1.2 0.3 -1.9 0.4 -1.1 -0.5 1.2 0.6 2.1 0.9 0.7 1.1 0.8 0.1 1.3 0.3 -0.0 0.5 1.1 0.8 0.1 1.4 0.7 0.4 0.7 0.6 0.1
Heart disease (mother) 0.4 0.5 3.1 0.1 -1.1 1.0 0.6 0.4 -0.7 0.2 -1.8 -1.0 -1.5 0.3 -0.1 0.7 -0.0 0.5 0.0 0.3 0.2 0.0 0.8 0.8 0.8 1.3 0.3 -1.3 0.6 0.7 0.1 -0.8 -0.4 0.3 0.6 -0.7 1.0 -0.3 -0.8 -0.4 0.1 -0.3 -0.7 0.8 0.3 -0.7 -0.5 0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.2 0.7 0.0 -0.2 0.1 -0.3 -0.3 -0.3 -0.5 0.4 0.3 -0.8 -0.1 -0.1 0.1 0.6 -0.4 -0.1 -0.2 -0.7 0.5 0.2 0.3 -0.7 -0.7 0.2 0.0 -0.4 -0.1 -0.5 -0.4 -0.2 -0.6 -0.7 -0.3 -0.6 0.1 -0.2 0.2 -0.2 -0.5 -0.3 -0.7 0.3 -0.4 -0.5 -0.8
Whole body fat mass 1.2 5.1 11.5 -2.8 -2.7 -1.1 -2.3 -2.5 -2.7 -2.5 0.2 -2.3 -0.5 -2.6 -3.0 -1.0 0.8 -1.7 -2.7 -2.2 -0.9 0.9 -1.1 1.9 -1.4 3.2 -0.9 -2.3 -2.1 -2.8 -2.1 -2.8 -2.9 -2.3 -1.6 -3.2 -1.0 -1.7 -2.8 -2.9 -2.8 -2.6 -3.4 -1.6 -2.7 -2.8 -2.7 -1.4
Leg fat mass (right) 0.6 2.3 5.8 -1.9 -1.8 -0.5 -1.6 -1.7 -1.7 -1.7 0.2 -1.8 -0.2 -1.8 -2.0 -0.7 0.9 -1.1 -1.8 -1.4 -0.3 0.9 -0.6 1.3 -1.0 2.2 -0.3 -1.8 -1.1 -1.7 -1.4 -1.9 -2.0 -1.6 -1.1 -2.2 -0.8 -0.9 -1.8 -1.9 -1.8 -1.7 -2.4 -1.2 -1.6 -1.8 -1.8 -1.0
Arm predicted mass (right) 0.8 4.0 9.9 -2.8 -2.3 -0.9 -2.2 -2.0 -2.5 -2.0 -0.3 -2.4 0.1 -2.2 -2.5 -0.6 1.4 -1.1 -2.1 -1.9 0.1 1.6 -1.2 3.0 -0.9 2.8 -0.1 -3.0 -0.7 -3.1 -1.7 -2.5 -2.6 -1.8 -1.0 -2.9 -1.2 -0.8 -2.1 -2.6 -2.2 -2.0 -3.1 -1.2 -2.1 -2.5 -2.3 -0.9
Pulse rate, automated reading 0.5 1.5 16.2 1.4 0.5 0.2 1.9 1.2 0.2 1.2 -4.0 -0.5 -0.5 1.1 1.1 1.9 -0.9 0.2 1.2 0.6 1.7 -1.0 1.5 -0.2 1.1 -0.4 -0.1 -1.3 1.8 1.8 1.2 0.6 0.9 1.3 1.0 1.0 1.9 -0.1 0.6 0.7 1.1 0.9 0.8 1.4 0.9 0.7 0.7 1.2
Alcohol intake frequency. 6.6 15.4 32.9 -3.6 -2.2 -4.9 -4.8 -4.9 -4.0 -5.1 -1.4 -5.3 -2.2 -4.8 -4.0 -3.2 1.6 -5.2 -4.4 -5.5 -4.3 1.5 -3.8 0.5 -5.5 3.0 -1.9 -2.2 -4.2 -1.2 -4.1 -2.8 -3.8 -5.2 -5.5 -3.9 -4.4 -2.5 -3.0 -3.0 -4.5 -4.1 -3.5 -5.5 -2.9 -3.1 -3.7 -5.7
Comparative height size at age 10 6.2 34.3 63.0 -6.9 -7.1 -4.7 -6.3 -6.3 -7.3 -6.0 -2.9 -4.4 -4.8 -6.6 -7.4 -4.1 -1.9 -5.7 -6.9 -6.1 -2.2 -1.2 -5.6 6.6 -3.5 4.5 -5.5 -7.9 -5.2 -5.5 -6.8 -6.9 -7.6 -5.4 -4.1 -7.5 -1.2 -6.6 -6.9 -7.8 -6.9 -6.1 -7.1 -3.4 -7.0 -6.8 -6.6 -3.1
Number of full sisters 3.6 4.4 14.7 -2.3 -0.8 -2.7 -2.2 -2.3 -2.1 -2.7 -0.6 -3.8 -0.8 -2.3 -1.6 -2.1 1.5 -2.6 -2.0 -3.0 -1.9 1.2 -2.0 -0.9 -3.3 1.8 -0.2 -0.2 -1.1 0.3 -2.0 -1.2 -1.4 -3.0 -3.2 -1.6 -3.5 -0.6 -1.5 -0.7 -2.0 -2.3 -1.5 -3.4 -0.8 -1.5 -1.8 -3.4
Suffer from ‘nerves’ 1.1 1.7 3.7 1.4 1.9 1.4 1.4 1.0 1.5 1.2 -1.7 0.9 -0.3 1.1 1.3 1.7 1.1 1.2 1.4 1.1 -0.2 1.1 1.4 -1.1 0.8 -0.8 1.5 1.1 1.6 0.6 1.8 1.8 1.5 1.3 1.1 1.5 0.2 1.7 1.9 1.3 1.3 1.6 1.4 0.7 0.9 1.8 1.7 0.7
Overall health rating 0.3 0.7 14.1 1.0 0.6 -0.7 0.8 0.3 0.3 0.3 -3.8 -0.3 -0.3 0.3 0.5 0.5 -0.3 -0.6 0.4 0.3 0.0 -0.5 0.8 -0.8 -0.3 -1.1 -0.4 -1.6 1.3 1.3 0.6 0.6 0.6 0.2 -0.3 0.7 0.5 -0.1 0.4 0.7 0.3 0.4 0.7 -0.1 0.5 0.6 0.4 -0.4
Chest pain or discomfort 0.3 0.4 3.0 0.6 0.0 -0.7 0.2 0.3 -0.1 0.1 1.1 0.3 1.4 0.2 0.2 -0.5 -1.3 -0.5 0.3 0.1 0.5 -1.3 0.5 -1.7 -0.1 -1.1 -0.9 -0.4 -0.2 1.0 -0.3 -0.1 0.4 0.0 -0.2 0.6 0.4 -0.5 -0.1 0.5 0.1 -0.3 0.4 0.1 -0.1 -0.1 -0.2 -0.0
Had major operations 2.1 2.4 11.8 2.2 1.0 1.5 1.9 1.6 1.8 1.6 1.5 3.4 1.3 1.6 1.5 0.6 -1.3 1.5 1.5 1.9 1.5 -1.3 2.1 -1.3 1.3 -2.9 0.2 1.1 0.9 1.0 1.1 1.3 1.6 1.5 1.5 1.8 1.5 0.5 1.2 1.3 1.5 1.4 1.8 1.4 1.1 1.4 1.5 1.6
Age at last live birth 3.3 4.8 10.8 2.6 2.7 2.1 2.4 2.4 2.6 2.4 -1.0 1.5 1.2 2.5 2.9 0.9 -0.1 1.9 2.6 2.2 0.2 -0.3 1.5 -1.5 1.4 -1.6 1.7 1.5 2.6 2.2 2.1 2.9 2.9 2.2 1.9 3.0 0.5 2.2 2.8 3.0 2.7 2.7 3.3 1.4 2.7 2.9 2.9 1.5
Family relationship satisfaction 1.1 1.4 3.8 1.6 1.4 0.7 1.2 1.1 1.2 1.1 -0.3 0.4 -0.3 1.1 1.3 -0.0 -1.0 0.7 1.5 0.7 1.4 -0.9 0.9 -0.8 0.7 -1.5 0.3 0.5 1.9 1.5 0.8 1.6 1.3 1.3 1.0 1.5 0.5 0.6 1.6 1.2 1.3 1.6 2.0 0.8 1.2 1.6 1.7 0.9
Leg pain on walking 0.3 0.4 1.3 0.1 -0.5 -0.6 -0.1 -0.3 -0.6 -0.6 -0.1 0.3 -0.3 -0.3 -0.2 -1.1 -0.9 -0.9 -0.4 -0.4 0.0 -1.0 -0.3 -0.0 -0.9 -1.0 -0.9 -0.6 -0.8 0.5 -1.1 -0.8 -0.2 -0.8 -1.0 -0.2 -0.4 -0.8 -0.5 0.2 -0.4 -0.8 -0.1 -0.7 0.1 -0.8 -0.8 -0.8
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 3.4 -1.0 -1.1 -1.6 -0.8 -1.1 -1.4 -1.3 -1.1 -1.3 -1.4 -1.0 -1.1 -1.2 -0.6 -1.2 -1.2 -1.3 -1.0 -0.5 -0.9 -0.2 -1.2 0.3 -1.0 0.1 -1.8 -0.1 -1.1 -1.3 -1.2 -1.2 -1.4 -1.1 -1.0 -1.3 -1.3 -1.0 -1.1 -1.4 -0.9 -1.0 -0.8 -1.3 -1.4 -1.3
Commuting to job workplace: Car/motor vehicle 0.8 0.9 2.1 0.5 0.5 1.3 1.1 1.0 0.6 1.1 -1.2 -0.7 -0.0 1.1 0.8 1.4 0.3 1.5 0.9 1.1 -0.2 0.6 1.4 0.1 1.4 1.3 1.2 0.0 1.1 0.3 1.4 0.5 0.7 1.2 1.3 0.5 0.9 0.9 0.7 0.5 1.0 0.8 0.4 1.3 0.8 0.6 0.7 1.3
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 2.2 0.7 -0.7 1.2 0.9 0.8 -0.2 0.6 0.6 0.4 0.2 0.7 0.2 1.5 -0.5 1.0 0.4 0.6 0.8 -0.5 0.6 -0.0 1.1 0.5 0.0 0.3 -0.2 0.6 0.2 -0.7 0.0 0.6 1.0 -0.1 1.5 -0.1 -0.5 -0.1 0.5 -0.1 -0.4 1.2 0.2 -0.5 -0.3 1.3
Medication: Aspirin 0.1 0.2 2.8 -0.3 -0.0 -0.2 0.7 0.0 -0.1 0.2 -1.7 0.1 -0.4 -0.1 -0.1 -0.0 -0.7 -0.2 -0.0 0.2 0.5 -0.8 -0.0 -0.7 0.2 -0.6 -0.6 -0.8 0.7 0.5 -0.0 -0.1 0.0 0.1 0.2 0.2 0.3 -0.4 -0.1 -0.1 -0.1 -0.0 0.3 0.3 -0.7 -0.1 -0.1 0.4
Supplements: Vitamin C 0.3 0.4 2.4 -0.5 -0.8 -0.2 -0.2 -0.5 -0.8 -0.4 -1.2 -0.5 -0.2 -0.6 -0.7 0.9 -0.4 -0.3 -0.5 -0.4 0.3 -0.4 0.5 0.7 -0.1 0.1 -0.7 -1.5 0.4 -0.3 -0.6 -0.7 -0.7 -0.4 -0.1 -0.7 0.6 -0.7 -0.7 -0.8 -0.6 -0.4 -0.9 -0.1 -0.6 -0.7 -0.6 0.0
Knee pain experienced in last month 0.6 0.9 4.5 0.8 0.5 1.2 1.1 0.7 0.6 1.0 -2.1 1.6 -0.1 0.7 0.5 1.6 -0.0 0.7 0.7 0.9 1.0 0.1 1.3 0.9 1.1 -1.2 0.3 -1.4 1.2 0.8 0.9 0.6 0.5 1.1 1.1 0.5 1.4 0.3 0.8 0.2 0.7 1.1 0.4 1.1 0.4 0.7 0.8 1.1
Hypertension (Self-reported) 2.5 7.0 18.7 1.9 2.7 3.8 3.4 2.4 2.8 3.0 -2.8 1.3 0.3 2.4 2.4 4.3 1.6 3.4 2.4 2.9 1.0 1.7 3.2 -0.5 3.0 0.6 3.1 1.3 4.0 -0.1 3.0 2.7 2.6 3.1 3.4 2.4 2.1 3.2 3.2 2.0 2.6 3.6 1.8 2.5 1.9 2.9 3.1 3.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.6 3.1 15.5 1.3 2.5 1.1 1.7 1.4 2.1 1.2 0.3 1.0 1.7 1.6 2.1 1.6 1.1 1.5 1.8 1.6 -0.2 0.9 2.0 -3.9 0.1 -1.3 1.9 3.2 2.0 2.3 1.7 2.1 2.3 0.9 0.4 2.3 -0.7 2.2 1.9 2.5 1.8 1.1 1.9 0.1 1.8 2.0 1.7 0.1
Illnesses of father: Heart disease 1.1 1.5 5.2 1.2 1.8 1.2 1.3 0.7 1.6 0.9 -0.4 1.3 -0.4 0.8 1.3 0.3 0.3 0.9 1.2 0.8 -0.1 0.1 1.8 -2.3 0.2 -1.7 0.8 1.1 1.3 0.8 1.4 1.9 1.4 0.8 0.5 1.6 -0.9 1.2 1.7 1.3 1.1 1.4 2.1 0.1 0.9 1.8 1.7 0.1
Illnesses of siblings: Diabetes 0.4 0.5 8.0 0.5 -0.4 -0.2 0.4 0.3 -0.1 0.5 -2.8 0.3 -1.6 0.2 -0.1 -0.0 -0.9 -0.0 0.0 0.5 0.6 -0.8 0.8 -0.3 0.7 -1.0 -0.9 -0.8 0.6 1.6 0.6 -0.1 -0.2 0.5 0.3 -0.1 1.3 -0.8 -0.3 -0.4 0.0 -0.0 -0.0 0.9 -0.2 -0.1 -0.1 0.4
Smoking status: Previous 0.6 0.9 5.0 0.6 -0.6 0.6 0.9 1.2 0.4 0.9 2.1 1.6 0.4 1.0 0.5 -0.6 -1.5 0.8 0.7 1.3 2.2 -1.8 0.5 0.7 1.3 -1.1 -0.8 0.1 0.1 0.3 0.4 -0.4 0.3 1.0 0.9 0.3 1.6 -0.7 -0.3 0.2 0.7 0.1 0.4 1.6 0.3 -0.3 -0.1 1.2
Forced expiratory volume in 1-second (FEV1), predicted 4.8 9.9 21.9 -3.4 -3.0 -4.2 -3.8 -3.1 -3.9 -3.5 -1.1 -4.7 -3.4 -3.2 -3.2 -4.0 -0.0 -3.9 -3.3 -3.8 -1.5 0.1 -4.2 1.4 -3.0 2.9 -2.3 -2.5 -2.8 -0.7 -3.1 -3.2 -3.2 -3.5 -3.5 -3.3 -3.0 -2.7 -3.5 -2.8 -3.3 -4.0 -2.9 -2.8 -2.9 -3.3 -3.5 -3.2
Whole body fat-free mass 0.9 5.4 14.6 -3.1 -3.0 -1.2 -2.6 -2.3 -2.9 -2.1 -0.0 -2.5 -0.0 -2.5 -3.0 -1.0 1.1 -1.3 -2.5 -2.1 -0.2 1.3 -1.7 3.5 -0.6 3.1 -0.6 -3.4 -1.1 -3.8 -2.0 -3.0 -3.1 -1.8 -0.9 -3.5 -0.8 -1.4 -2.6 -3.2 -2.6 -2.3 -3.6 -1.0 -2.7 -2.9 -2.7 -0.7
Leg fat-free mass (right) 0.6 3.1 12.2 -2.3 -2.4 -0.7 -1.9 -1.5 -2.1 -1.4 1.2 -1.6 0.7 -1.6 -2.2 -0.6 1.0 -0.6 -1.6 -1.3 -0.0 1.2 -0.8 2.5 -0.0 2.5 -0.2 -2.2 -1.1 -3.5 -1.2 -2.5 -2.4 -1.1 -0.4 -2.7 -0.3 -1.0 -2.1 -2.5 -1.8 -1.9 -3.0 -0.3 -2.0 -2.4 -2.2 -0.2
Arm fat percentage (left) 0.5 1.8 5.3 -1.2 -2.2 0.1 -1.0 -1.1 -1.4 -1.2 1.8 -0.5 0.5 -1.3 -1.7 -0.4 0.0 -0.5 -1.5 -0.7 -0.2 -0.0 0.1 1.1 -0.3 1.8 -0.8 -1.2 -1.9 -2.2 -1.2 -2.1 -1.8 -1.2 -0.6 -2.0 0.3 -1.3 -2.1 -1.8 -1.5 -1.7 -2.3 -0.4 -1.6 -2.0 -1.9 -0.3
Average weekly red wine intake 0.6 0.9 2.7 1.0 -0.0 1.3 1.4 1.3 0.4 1.3 0.9 0.4 0.8 1.3 1.0 0.5 -0.6 1.4 1.1 1.1 0.0 -0.5 0.8 0.3 1.6 0.9 0.6 0.8 -0.3 -1.1 0.8 0.2 0.8 1.3 1.5 0.8 0.9 0.5 0.2 0.7 1.1 0.6 0.9 1.7 0.8 0.3 0.6 1.6
Handedness (chirality/laterality): Left-handed 1.2 1.5 7.3 -1.8 0.2 -1.4 -1.7 -1.7 -0.3 -1.6 -0.4 -0.7 -0.8 -1.7 -1.1 -1.4 1.1 -1.3 -1.3 -1.4 -0.5 1.3 -1.4 0.4 -2.1 0.3 0.1 -0.1 -0.4 -0.7 -1.3 0.0 -0.9 -1.7 -1.7 -0.8 -2.7 0.0 -0.1 -0.8 -1.3 -0.8 -0.4 -2.3 -1.1 -0.1 -0.3 -2.0
Mood swings 3.0 5.5 15.1 3.2 1.0 2.8 2.7 2.7 2.2 3.1 0.5 2.9 1.3 2.7 2.1 2.9 -1.4 2.8 2.6 3.0 1.4 -1.4 3.0 0.3 3.5 -1.5 0.6 0.3 1.4 0.1 2.2 1.5 2.0 3.3 3.4 2.0 3.9 0.9 1.7 1.4 2.5 2.6 1.8 3.6 1.5 1.7 2.1 3.7
Loneliness, isolation 1.2 1.6 6.5 1.4 1.6 1.1 1.2 0.8 1.8 1.2 -0.6 2.3 0.3 0.9 1.1 1.4 -0.3 1.1 1.2 1.1 0.3 -0.3 1.0 -0.8 0.8 -2.5 0.4 0.4 1.3 0.4 1.0 1.9 1.4 1.3 1.3 1.5 1.1 0.9 1.8 1.0 1.1 2.0 1.4 0.8 0.7 1.9 1.9 1.2
Long-standing illness, disability or infirmity 0.1 0.2 1.1 -0.2 -0.1 -0.3 0.1 -0.5 -0.2 -0.4 -0.5 0.1 -0.1 -0.5 -0.4 0.2 0.3 -0.3 -0.4 -0.3 -0.3 0.4 1.0 0.1 -0.4 -0.9 0.0 -0.7 0.0 -0.4 -0.2 0.0 -0.4 -0.4 -0.4 -0.4 -0.5 -0.1 -0.1 -0.3 -0.5 -0.2 -0.3 -0.5 -0.3 -0.0 -0.1 -0.5
Ever had bowel cancer screening 1.9 2.3 6.9 1.6 0.2 1.6 1.5 1.7 1.2 1.8 2.3 2.6 0.1 1.6 1.1 0.4 -1.9 1.5 1.3 2.0 2.4 -1.8 1.4 -0.2 2.2 -2.5 -0.5 0.9 0.6 1.2 1.1 0.6 0.9 2.0 1.9 1.1 2.5 -0.3 0.5 0.5 1.3 1.1 1.1 2.4 0.6 0.7 0.9 2.2
Diabetes diagnosed by doctor 0.3 0.6 5.4 0.1 0.2 -1.5 -0.4 -0.6 -0.2 -0.4 -2.3 -0.3 -1.4 -0.6 -0.4 -1.3 -1.0 -0.9 -0.5 -0.6 -0.1 -1.0 -1.1 -0.5 -0.7 -1.4 -1.1 -0.2 0.2 0.3 -0.7 0.2 -0.2 -0.4 -0.6 0.2 -0.4 -0.7 0.1 -0.3 -0.5 -0.0 0.5 -0.6 -0.6 0.1 0.1 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.3 4.6 0.2 1.2 1.0 1.0 1.0 1.0 1.1 -0.1 -0.6 1.2 0.9 0.9 1.4 1.8 1.3 1.1 0.9 1.1 1.9 0.8 0.9 1.3 1.4 2.1 0.7 1.8 0.3 1.7 1.0 0.9 1.4 1.4 0.6 0.4 1.8 1.5 0.6 1.1 1.4 0.2 1.0 0.8 1.0 1.0 1.1
Friendships satisfaction 1.5 1.9 5.3 1.0 1.4 1.4 1.3 1.3 1.3 1.2 -0.4 0.6 1.1 1.3 1.4 2.2 1.9 1.5 1.5 1.3 1.5 2.0 1.4 -0.7 1.0 0.2 2.3 1.9 2.1 1.4 1.9 1.3 1.4 1.2 1.0 1.1 0.2 2.1 1.4 1.3 1.4 1.1 0.6 0.8 1.5 1.2 1.2 0.6
Qualifications: nursing, teaching 0.2 0.4 1.5 0.7 -0.5 0.8 0.4 0.6 0.0 0.5 0.5 0.4 0.6 0.5 0.2 -0.4 -1.2 0.6 0.3 0.5 0.6 -1.2 0.8 0.7 0.9 0.4 -0.3 -1.2 0.5 -0.3 -0.4 -0.2 0.1 0.5 0.9 0.1 1.2 -0.3 -0.1 0.1 0.4 0.7 0.1 0.9 0.5 -0.1 0.2 1.2
Commuting to job workplace: Walk 1.0 1.1 3.2 -1.4 -0.5 -1.8 -1.6 -1.4 -0.9 -1.1 0.0 -0.6 0.5 -1.5 -1.3 -1.4 -0.4 -1.4 -1.3 -1.3 -0.6 -0.3 -1.8 0.8 -0.9 -0.2 -1.3 -0.8 -0.9 -0.8 -1.2 -0.6 -1.2 -0.8 -0.9 -1.0 -0.5 -1.2 -0.5 -1.4 -1.3 -0.6 -0.9 -0.9 -1.6 -0.7 -0.7 -0.7
Eye problems/disorders: Cataract 0.4 0.4 1.8 -0.3 -0.1 -0.1 -0.9 -0.6 -0.6 -0.8 -1.3 -1.4 -0.2 -0.6 -0.3 0.0 0.9 -0.4 -0.5 -1.0 -1.0 1.0 -1.1 0.1 -1.0 0.9 0.6 0.3 0.1 -0.7 -0.6 -0.2 -0.2 -0.9 -0.7 -0.4 -1.1 0.3 -0.1 0.1 -0.4 -0.4 -0.6 -1.1 0.2 -0.3 -0.3 -0.8
Mouth/teeth dental problems: Mouth ulcers 0.9 1.4 4.3 -0.9 -1.9 -0.8 -0.7 -0.6 -1.1 -0.5 2.1 1.2 0.4 -0.8 -1.4 -0.4 -1.3 -0.3 -0.9 -0.3 1.5 -1.1 -0.3 2.0 0.4 -0.0 -1.6 -1.1 -1.5 -1.4 -0.9 -1.8 -1.5 -0.3 0.0 -1.4 1.2 -1.8 -1.5 -1.8 -1.1 -1.0 -1.5 0.5 -1.5 -1.6 -1.4 0.5
Medication for cholesterol 1.0 1.5 3.6 -1.0 -1.2 -1.7 -1.7 -1.2 -1.2 -1.3 1.4 0.0 0.1 -1.2 -1.3 -1.9 -0.3 -1.5 -1.3 -1.2 0.1 -0.4 -1.5 1.6 -1.2 -0.4 -1.3 -0.3 -1.7 -0.1 -1.2 -1.2 -1.3 -1.3 -1.4 -1.3 -0.8 -1.4 -1.5 -1.2 -1.4 -1.6 -1.2 -1.0 -1.3 -1.3 -1.4 -1.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.4 3.0 0.2 0.3 1.0 0.3 0.1 0.4 0.1 1.6 1.7 1.2 0.1 0.1 0.4 -0.6 0.5 0.4 0.3 -0.3 -0.6 0.8 -1.0 -0.0 -1.4 -0.2 1.2 -0.2 -0.4 0.1 0.1 0.3 0.1 0.1 0.5 -0.1 0.0 0.2 0.2 0.1 -0.0 0.5 0.0 -0.4 0.1 0.1 0.2
Back pain experienced in last month 3.8 5.5 12.4 3.2 1.8 2.0 3.0 2.7 2.4 2.8 -0.9 2.8 0.9 2.7 2.4 3.0 -0.8 2.3 2.8 3.0 2.6 -0.7 3.5 -0.4 2.6 -2.8 0.9 0.1 2.7 1.9 2.5 2.1 2.4 2.9 2.6 2.5 2.9 1.3 2.2 2.0 2.6 2.5 2.2 2.7 2.0 2.2 2.3 2.6
Mineral and other dietary supplements 1.0 1.3 5.4 -1.1 0.8 -1.3 -1.3 -1.0 -0.2 -1.1 -0.7 -2.3 -0.7 -0.9 -0.2 0.4 2.2 -0.9 -0.6 -1.3 -0.8 2.0 -2.0 -0.9 -1.9 1.7 1.0 1.4 -0.3 -0.7 -0.5 0.5 0.1 -1.4 -1.4 -0.1 -1.9 1.1 0.4 0.4 -0.6 -0.3 -0.4 -2.1 0.2 0.3 -0.0 -1.8
Breast cancer (self-reported) 0.7 0.9 9.1 0.0 -1.5 0.3 0.5 0.4 -1.0 0.3 0.6 -0.1 -0.2 0.2 -0.4 1.2 0.3 0.6 0.0 0.2 0.9 0.3 0.4 3.0 1.3 1.5 0.3 -1.2 -1.0 -1.2 0.0 -1.4 -0.8 0.5 0.9 -1.1 1.3 -0.3 -1.0 -0.8 -0.0 -0.2 -1.4 1.2 0.0 -1.2 -0.9 1.1
Asthma (self-reported) 1.2 2.4 5.0 1.6 2.1 1.3 1.9 1.3 1.9 1.6 -0.4 1.4 0.0 1.4 1.5 2.0 1.1 1.7 1.6 1.6 0.8 1.3 2.2 -1.4 1.1 -1.7 1.8 1.7 1.9 0.8 2.0 1.9 1.7 1.5 1.2 1.6 -0.1 2.0 2.0 1.5 1.5 1.6 1.6 0.9 1.2 1.9 1.8 0.8
Osteoporosis (self-reported) 2.3 2.8 8.7 -0.6 -2.8 -0.5 -1.3 -1.0 -2.1 -1.2 2.7 -0.1 -0.5 -1.2 -1.8 -1.4 -1.6 -0.9 -1.6 -1.2 -0.1 -1.5 -0.7 2.0 -0.2 1.0 -2.0 -1.4 -2.9 -1.8 -2.1 -2.7 -2.0 -1.1 -0.7 -2.0 0.7 -2.2 -2.5 -1.9 -1.6 -2.0 -2.1 -0.0 -1.7 -2.6 -2.3 -0.1
Osteoarthritis (self-reported) 1.0 1.3 8.2 1.3 -0.6 1.2 1.3 1.2 0.6 1.2 0.9 2.9 1.1 1.1 0.5 0.8 -1.5 1.2 0.9 1.5 1.3 -1.4 1.6 0.8 1.8 -1.9 -0.4 -0.3 -0.4 -0.3 0.6 -0.2 0.3 1.3 1.5 0.3 2.2 -0.5 -0.1 0.1 0.8 0.6 0.3 1.9 0.5 -0.0 0.3 1.8
Medication: Aspirin 0.2 0.2 2.4 -0.0 0.1 0.2 1.1 0.3 0.1 0.5 -1.5 -0.0 -0.3 0.2 0.2 0.7 -0.3 0.2 0.2 0.4 0.8 -0.3 0.4 -0.7 0.6 -0.2 -0.0 -0.2 0.8 0.5 0.3 0.0 0.3 0.4 0.5 0.4 0.5 0.1 0.1 0.2 0.2 0.1 0.3 0.5 -0.3 0.1 0.1 0.6
Medication: Gliclazide 1.8 2.0 7.1 1.5 1.8 0.7 1.1 0.9 1.6 1.0 -0.3 0.9 2.7 1.1 1.4 2.2 2.0 1.1 1.2 1.0 -1.0 1.9 1.6 -1.1 0.3 -1.4 2.3 1.4 1.6 -0.0 1.5 1.9 1.6 0.7 0.6 1.4 -0.1 2.1 1.6 1.8 1.3 1.4 0.9 -0.1 1.9 1.8 1.6 0.2
Illnesses of father: None of the above (group 1) 0.4 0.5 1.8 -0.2 -1.4 -0.2 -0.5 0.0 -1.1 -0.1 0.7 -1.2 -0.1 -0.0 -0.4 -0.2 0.2 -0.1 -0.4 -0.3 -0.4 0.3 -0.5 1.1 0.5 1.4 0.1 -0.3 -1.0 -0.7 -0.3 -1.3 -0.7 -0.2 0.1 -1.0 0.6 -0.4 -1.2 -0.5 -0.3 -0.9 -1.2 0.5 -0.1 -1.3 -1.1 0.2
Smoking status: Current 1.2 1.9 3.9 -1.4 -1.1 -2.0 -0.9 -1.7 -1.4 -1.6 -1.2 -1.1 0.2 -1.6 -1.6 -1.2 -0.9 -1.9 -1.5 -1.4 -1.8 -0.8 -0.9 -0.1 -1.6 0.6 -1.6 -1.5 -1.5 -0.7 -1.5 -1.2 -1.3 -1.6 -1.7 -1.1 -1.2 -1.6 -1.4 -1.2 -1.7 -1.9 -1.0 -1.4 -1.8 -1.3 -1.4 -1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.8 5.2 0.0 1.3 0.4 0.1 0.4 1.0 0.3 0.5 1.1 2.3 0.3 0.8 0.3 1.0 0.3 0.7 0.3 0.6 1.0 -0.2 -1.7 -0.5 -0.6 1.2 0.8 0.7 0.8 0.3 1.3 1.0 -0.1 -0.0 1.0 -0.8 1.3 1.1 1.2 0.6 0.8 1.0 -0.7 0.9 1.2 1.0 -0.2
Whole body water mass 1.0 5.5 14.6 -3.2 -2.9 -1.3 -2.7 -2.3 -2.9 -2.2 0.0 -2.5 -0.1 -2.5 -3.0 -1.0 1.1 -1.4 -2.5 -2.2 -0.2 1.4 -1.7 3.4 -0.7 3.0 -0.6 -3.3 -1.2 -3.8 -2.0 -3.0 -3.1 -1.9 -1.0 -3.5 -0.9 -1.4 -2.6 -3.2 -2.6 -2.4 -3.6 -1.1 -2.7 -2.9 -2.7 -0.8
Leg predicted mass (right) 0.6 3.0 12.8 -2.3 -2.3 -0.6 -1.9 -1.5 -2.0 -1.4 1.4 -1.5 0.8 -1.6 -2.2 -0.6 1.0 -0.5 -1.6 -1.2 -0.0 1.3 -0.8 2.5 0.0 2.5 -0.1 -2.1 -1.1 -3.6 -1.1 -2.4 -2.3 -1.1 -0.3 -2.6 -0.3 -0.9 -2.0 -2.5 -1.7 -1.8 -2.9 -0.3 -2.0 -2.3 -2.0 -0.1
Arm fat mass (left) 0.7 3.0 8.4 -1.9 -2.5 -0.3 -1.6 -1.6 -2.0 -1.6 1.2 -1.4 0.3 -1.8 -2.3 -0.6 0.5 -0.8 -1.9 -1.3 -0.3 0.6 -0.5 1.9 -0.5 2.5 -0.6 -2.1 -1.7 -2.9 -1.6 -2.5 -2.3 -1.5 -0.8 -2.6 -0.2 -1.3 -2.4 -2.3 -2.0 -2.0 -2.9 -0.7 -1.9 -2.4 -2.2 -0.6
Number of self-reported non-cancer illnesses 2.0 3.5 11.0 2.0 1.9 2.6 2.4 1.3 2.0 1.9 -3.1 2.1 -0.3 1.4 1.5 3.3 1.0 2.3 1.6 1.9 -0.6 1.1 3.1 -0.5 1.7 -1.2 2.1 0.4 2.5 -1.0 1.9 1.9 1.7 1.8 2.1 1.6 1.3 2.0 2.2 1.4 1.6 2.5 1.3 1.3 1.5 2.0 2.1 1.9
Average weekly champagne plus white wine intake 0.3 0.4 2.7 -0.1 -0.3 0.6 0.4 0.4 0.2 0.5 0.2 0.9 1.3 0.2 -0.1 1.0 -0.7 0.5 0.2 0.7 1.4 -0.7 0.3 0.6 1.0 -0.6 -0.6 -0.9 0.8 -0.2 0.4 -0.3 -0.0 0.6 0.7 0.0 1.6 -0.4 -0.1 -0.3 0.0 0.4 -0.3 0.9 -0.5 -0.2 -0.1 1.0
Miserableness 3.2 5.6 10.7 3.0 1.9 2.2 2.4 2.7 2.7 3.1 1.1 2.5 2.0 2.8 2.5 2.1 -1.2 2.6 2.9 2.9 0.4 -1.2 2.7 -0.5 3.0 -2.2 0.8 0.7 1.5 0.3 2.5 2.3 2.4 3.3 3.2 2.5 3.0 1.2 2.4 1.8 2.8 2.9 2.6 3.2 1.9 2.5 2.7 3.3
Guilty feelings 2.3 3.5 6.5 2.0 1.7 1.9 2.1 2.0 2.4 2.2 1.3 2.5 1.3 2.0 1.9 2.5 0.2 2.3 2.1 2.4 1.5 0.3 2.3 -0.4 1.9 -2.0 1.5 1.6 1.8 0.5 2.0 1.9 1.9 2.1 2.1 1.9 1.8 1.6 2.0 1.7 2.0 2.3 1.6 1.8 1.7 2.0 2.1 2.0
Wears glasses or contact lenses 0.5 0.6 4.7 -0.3 0.4 -0.7 -0.4 -0.3 0.1 -0.5 -0.5 0.4 -1.1 -0.4 -0.0 -1.6 -0.8 -1.0 -0.1 -0.2 1.1 -0.9 -0.3 -0.7 -1.1 -2.0 -0.9 -0.1 0.9 2.2 -0.6 0.4 0.1 -0.6 -1.0 0.3 -1.0 -0.5 0.2 0.3 -0.3 -0.3 0.8 -0.9 -0.1 0.3 0.1 -1.0
Ever taken oral contraceptive pill 0.2 0.2 0.9 0.4 0.2 0.6 0.8 0.6 0.3 0.6 0.0 0.6 0.3 0.6 0.5 0.8 0.0 0.5 0.5 0.7 0.0 -0.1 0.5 -0.4 0.6 -0.2 0.2 0.5 0.2 0.9 0.6 -0.0 0.5 0.5 0.4 0.5 0.7 0.3 0.1 0.5 0.5 0.2 0.1 0.6 0.4 0.0 0.0 0.4
Hearing aid user 2.5 2.8 6.9 1.9 2.1 1.9 1.8 1.7 2.0 1.8 -1.0 1.3 -0.6 1.7 2.0 0.8 -0.9 1.2 1.8 1.6 0.5 -1.0 0.7 -2.0 1.0 -2.3 0.4 1.2 1.9 1.8 1.5 2.2 2.1 1.7 1.3 2.4 1.0 1.1 2.1 1.8 1.9 1.9 2.6 1.2 1.4 2.2 2.2 1.2
Mother’s age at death 0.5 0.7 3.2 -0.2 -1.3 -1.0 -0.4 0.0 -0.6 -0.2 1.0 0.5 1.8 -0.2 -0.4 -1.5 -1.5 -0.6 -0.2 -0.1 1.3 -1.7 -0.0 0.6 0.1 -0.8 -1.4 -1.5 -0.1 0.1 -0.7 -0.9 -0.6 -0.2 -0.1 -0.5 1.1 -1.4 -1.0 -0.5 -0.4 -0.5 -0.4 0.3 -0.2 -0.8 -0.7 0.3
Financial situation satisfaction 0.2 0.3 3.2 0.2 0.2 0.5 0.6 0.3 0.4 0.4 1.2 0.8 1.8 0.3 0.3 0.3 -0.6 0.3 0.6 0.4 0.2 -0.7 0.4 -0.5 0.5 -0.2 -0.2 0.3 -0.4 -0.8 0.1 0.2 0.3 0.6 0.5 0.4 0.5 -0.1 0.4 0.2 0.3 0.4 0.5 0.5 -0.1 0.2 0.3 0.6
Tinnitus: Yes, now most or all of the time 1.6 1.9 6.3 1.5 1.8 0.3 0.9 1.3 1.8 1.1 1.4 1.7 -0.1 1.5 1.7 -1.2 -0.4 0.8 1.4 1.4 -0.1 -0.5 0.7 -2.5 0.1 -2.2 0.5 1.9 0.8 1.7 1.2 1.7 1.8 0.9 0.2 2.0 -0.9 1.1 1.5 2.0 1.5 0.8 2.4 0.3 1.4 1.6 1.4 -0.1
Commuting to job workplace: Public transport 0.3 0.4 2.0 -0.9 -0.4 -0.8 -0.5 -0.9 -0.6 -0.6 0.1 0.1 0.8 -1.0 -0.9 -0.3 -0.4 -0.7 -0.8 -0.8 0.0 -0.5 -1.0 0.1 -0.4 0.4 -0.8 -0.0 -0.1 -0.9 -0.9 -0.4 -0.7 -0.5 -0.2 -0.5 -0.1 -0.7 -0.4 -0.9 -0.8 -0.4 -0.5 -0.4 -1.4 -0.4 -0.3 -0.0
Eye problems/disorders: Glaucoma 0.1 0.2 2.7 0.3 -0.1 0.4 0.0 0.0 -0.1 -0.1 -1.6 0.6 -1.1 -0.0 0.1 0.8 0.1 0.2 -0.1 0.0 -0.1 0.0 -0.2 -0.1 -0.2 -0.3 0.1 -0.3 1.0 -0.1 -0.3 -0.2 0.1 -0.3 -0.1 -0.0 0.2 0.2 -0.0 0.3 -0.0 0.1 -0.2 -0.4 0.5 -0.1 -0.1 -0.0
Medication: Blood pressure 1.7 3.2 9.6 1.8 1.8 2.3 2.2 1.8 1.8 2.0 -2.1 0.4 -0.7 1.8 1.9 2.2 0.2 2.1 1.8 1.8 1.2 0.4 2.1 -0.3 1.8 -0.3 1.7 0.0 3.1 0.3 1.7 2.0 1.9 2.0 2.1 1.9 1.3 1.8 2.2 1.7 2.0 2.4 1.9 1.6 1.8 2.1 2.2 1.9
Pain type(s) experienced in last month: Hip pain 0.8 1.0 10.1 0.6 -0.6 1.0 0.4 0.2 0.3 0.6 0.4 3.2 -0.0 0.2 -0.3 0.1 -1.7 0.6 0.1 0.9 1.4 -1.5 1.3 0.7 1.2 -2.5 -1.2 -0.7 0.1 -0.2 0.0 -0.2 -0.3 0.8 1.0 -0.1 1.6 -1.0 -0.3 -0.8 -0.0 0.2 -0.0 1.4 -0.9 -0.1 0.1 1.4
Supplements: Fish oil (including cod liver oil) 2.0 2.6 7.5 1.8 0.4 2.4 2.0 1.6 1.4 2.1 -0.3 2.5 0.9 1.6 1.1 0.9 -1.7 1.8 1.4 2.1 0.2 -1.6 2.0 0.1 2.6 -1.8 -0.1 -0.9 1.3 0.3 1.4 0.8 1.1 2.3 2.5 1.2 2.5 0.2 0.9 0.5 1.4 1.7 1.3 2.7 0.5 1.0 1.4 2.7
High cholesterol (Self-reported) 0.7 1.2 10.5 -0.2 1.3 -0.5 -0.0 -0.7 0.7 -0.4 -1.6 1.4 -0.8 -0.5 0.1 -0.9 -1.0 -0.8 -0.3 -0.4 -2.0 -1.2 -1.0 -3.2 -1.4 -1.9 -1.0 0.1 -0.0 -0.0 -0.7 1.2 0.6 -0.7 -0.9 1.2 -1.6 -0.2 0.9 0.5 -0.3 0.1 1.8 -1.4 -0.7 1.1 0.9 -0.9
Medication: Bendroflumethiazide 3.5 5.3 12.2 2.0 2.7 2.3 2.7 2.2 2.7 2.3 -2.3 1.5 1.0 2.2 2.6 3.1 1.8 2.5 2.4 2.5 0.6 1.7 2.6 -1.4 1.5 -1.1 3.0 1.8 3.5 0.1 2.6 2.7 2.7 2.0 1.9 2.4 0.6 3.0 2.8 2.8 2.5 2.8 2.1 1.1 2.8 2.7 2.6 1.4
Medication: Paracetamol 0.1 0.2 1.7 -0.6 0.0 0.2 0.1 -0.2 -0.1 0.0 -1.0 -0.7 -0.2 -0.2 -0.3 0.5 -0.0 -0.3 -0.1 -0.2 0.4 0.1 0.0 0.7 0.2 0.6 -0.1 -1.3 0.2 -0.2 0.1 0.0 -0.3 0.2 0.3 -0.1 0.3 -0.1 0.0 -0.6 -0.2 -0.0 -0.3 0.3 -0.8 0.0 0.1 0.3
Medication: Lisinopril 0.8 1.0 3.1 0.6 0.7 1.8 1.0 0.8 1.0 1.1 1.0 1.8 0.2 0.8 0.7 1.3 0.6 1.5 0.7 1.0 0.2 0.8 1.2 0.0 1.3 -0.8 1.2 1.1 0.8 -1.3 1.2 0.9 0.7 1.1 1.4 0.6 0.6 1.1 0.9 0.3 0.8 1.1 0.5 1.1 0.4 1.0 1.1 1.3
Medication: Atorvastatin 1.5 1.9 6.0 0.7 2.4 1.5 1.2 0.7 1.9 1.1 -2.1 0.1 -0.4 0.8 1.3 1.5 0.7 1.0 1.2 1.0 -0.6 0.8 0.5 -2.4 0.4 -0.6 1.3 0.7 2.3 0.3 1.4 2.3 1.6 1.0 0.9 1.9 -0.5 1.8 2.2 1.3 1.2 1.6 1.9 0.1 0.6 2.2 2.1 0.5
Illnesses of father: High blood pressure 0.2 0.3 2.0 0.0 0.6 -0.2 0.4 0.3 0.5 0.1 0.5 -0.1 -0.5 0.2 0.4 0.4 0.8 0.2 0.5 0.1 1.3 0.6 0.4 -1.0 -0.3 -0.2 0.7 1.4 0.5 1.2 0.5 0.4 0.4 -0.1 -0.2 0.4 -0.4 0.7 0.5 0.6 0.3 0.3 0.3 -0.4 0.6 0.4 0.3 -0.5
Alcohol drinker status: Never 6.4 7.6 18.6 -3.2 -1.1 -2.5 -3.4 -3.8 -2.5 -3.6 -0.4 -3.2 -3.0 -3.9 -3.1 -1.2 1.7 -3.4 -3.3 -4.2 -1.8 1.9 -2.8 0.3 -4.0 2.1 -0.9 -0.3 -2.5 -1.1 -3.0 -1.4 -2.7 -3.8 -3.8 -2.7 -3.4 -1.2 -1.7 -2.3 -3.4 -2.5 -2.6 -4.3 -2.5 -1.7 -2.2 -4.1
Ever smoked 0.5 0.9 4.5 0.6 -0.9 0.5 0.9 0.9 0.0 0.9 0.6 1.4 -0.2 0.7 0.1 0.2 -1.9 0.6 0.4 1.1 1.8 -2.1 0.3 0.8 1.5 -0.8 -1.3 -0.3 -0.1 0.1 0.2 -0.7 0.0 0.9 1.0 0.1 2.1 -1.1 -0.7 -0.2 0.3 -0.1 0.0 1.7 -0.4 -0.5 -0.2 1.5
Basal metabolic rate 1.1 6.0 15.4 -3.3 -3.0 -1.3 -2.8 -2.5 -3.0 -2.4 0.0 -2.7 -0.2 -2.7 -3.2 -1.1 1.2 -1.5 -2.6 -2.3 -0.3 1.5 -1.7 3.5 -0.9 3.3 -0.6 -3.4 -1.4 -3.9 -2.1 -3.1 -3.3 -2.1 -1.2 -3.6 -1.0 -1.5 -2.8 -3.3 -2.8 -2.5 -3.8 -1.2 -2.8 -3.0 -2.8 -1.0
Leg fat percentage (left) 0.1 0.5 2.4 -0.8 -0.4 0.1 -0.4 -0.8 -0.6 -0.9 -0.6 -1.3 -0.2 -0.9 -0.8 0.1 1.3 -0.3 -0.8 -0.7 -0.3 1.2 0.3 0.1 -0.8 1.5 0.6 -0.2 -0.4 -0.5 -0.3 -0.6 -0.7 -0.9 -0.7 -0.9 -1.0 0.2 -0.5 -0.6 -0.8 -0.7 -1.1 -1.0 -0.5 -0.6 -0.7 -0.9
Arm fat-free mass (left) 0.8 4.1 11.2 -2.9 -2.3 -0.8 -2.2 -2.1 -2.5 -1.9 -0.7 -2.6 -0.3 -2.2 -2.6 -0.6 1.3 -1.0 -2.1 -1.9 0.2 1.6 -1.3 3.2 -0.7 3.0 -0.2 -3.1 -0.5 -3.4 -1.7 -2.4 -2.6 -1.7 -0.8 -3.0 -1.1 -0.9 -2.0 -2.8 -2.2 -1.9 -3.1 -1.1 -2.3 -2.3 -2.1 -0.7
Number of operations (self-reported) 0.4 0.6 3.0 -0.1 -1.2 1.1 0.1 -0.1 -0.5 0.2 1.6 1.7 -0.8 -0.1 -0.7 0.1 -0.6 0.7 -0.3 0.3 0.2 -0.3 0.7 0.8 1.1 -0.5 -0.5 0.2 -1.2 -0.8 0.1 -1.1 -0.8 0.5 0.8 -0.8 0.8 -0.7 -0.8 -1.2 -0.3 -0.5 -0.8 1.1 -1.0 -0.9 -0.7 1.0
Average weekly beer plus cider intake 1.4 2.0 5.5 1.3 2.3 0.5 0.7 0.9 1.6 0.8 0.1 0.5 0.5 1.0 1.6 0.3 2.1 0.7 1.4 0.8 0.2 1.9 1.2 -1.4 -0.3 -1.6 2.2 2.1 1.6 0.9 1.8 1.9 1.7 0.4 -0.1 1.6 -1.7 2.3 1.9 2.0 1.3 1.1 1.8 -0.5 1.8 1.8 1.5 -0.7
Irritability 3.3 5.6 9.7 2.9 2.6 2.8 2.7 2.4 3.0 2.6 -0.1 2.8 0.8 2.4 2.6 2.5 -0.8 2.2 2.7 2.6 1.4 -1.0 2.2 -2.6 1.7 -3.1 1.0 1.2 2.3 1.6 1.8 2.9 2.9 2.3 2.2 3.1 2.0 1.7 2.8 2.6 2.5 3.0 3.1 1.6 2.2 3.0 3.0 2.2
Risk taking 0.6 0.9 6.6 0.9 -0.4 1.3 1.4 1.0 0.2 0.9 -0.6 0.7 2.6 0.9 0.5 1.7 -0.1 1.2 0.6 1.2 0.8 -0.1 1.4 1.6 1.3 1.0 0.7 -0.2 0.7 -0.6 0.3 -0.3 0.5 0.8 1.2 0.2 1.6 0.4 -0.0 0.5 0.7 0.6 -0.3 1.1 0.8 -0.1 0.1 1.4
Ever had prostate specific antigen (PSA) test 2.0 2.3 5.2 1.5 1.5 2.2 1.3 1.4 1.8 1.7 -0.4 1.6 0.0 1.5 1.6 1.4 0.4 2.1 1.5 1.6 0.5 0.5 1.3 0.5 1.6 -1.0 1.5 1.1 1.8 -0.7 1.6 1.8 1.5 1.8 2.1 1.5 0.7 1.7 1.8 1.1 1.7 2.3 1.6 1.5 1.4 1.9 2.1 1.9
Fractured/broken bones in last 5 years 1.0 1.3 7.5 -1.5 -0.8 -0.5 -1.6 -1.6 -0.8 -1.2 0.3 -0.8 -1.6 -1.5 -1.6 -0.8 0.3 -0.6 -1.3 -1.1 -0.4 0.6 -0.9 2.7 -0.6 0.4 -0.5 -1.9 -0.8 -2.1 -0.9 -0.7 -1.7 -0.9 -0.4 -1.6 -0.7 -0.8 -0.6 -2.0 -1.4 -0.4 -1.1 -0.8 -1.5 -0.6 -0.5 -0.5
Age started oral contraceptive pill 0.8 1.0 4.9 -0.8 -1.0 0.1 -0.5 -0.7 -0.9 -0.3 -2.2 -0.5 -1.8 -0.9 -1.1 -0.1 -1.5 -0.5 -0.9 -0.6 0.4 -1.4 -0.4 1.0 0.5 0.5 -1.7 -1.7 0.2 -0.8 -0.8 -0.6 -1.1 0.0 0.4 -0.7 1.2 -1.5 -0.7 -1.6 -0.9 -0.2 -0.6 0.5 -1.8 -0.5 -0.2 0.7
Diastolic blood pressure, automated reading 1.5 4.7 17.0 1.1 2.5 3.0 2.2 2.0 2.1 2.2 -2.7 0.2 -0.1 1.9 2.1 3.0 2.0 2.7 2.2 1.9 2.0 2.0 1.9 -0.2 2.0 0.7 3.0 1.4 4.1 0.9 2.8 2.3 2.1 2.3 2.4 1.9 0.8 3.0 2.8 1.8 2.3 2.8 1.5 1.6 1.9 2.4 2.5 2.0
Ever depressed for a whole week 0.3 0.4 4.1 0.2 0.2 -0.2 -0.7 -0.7 -0.2 -0.5 0.2 -0.4 -0.4 -0.6 -0.3 -0.3 0.7 -0.6 -0.6 -0.9 -2.0 0.8 -0.7 0.2 -0.8 0.2 0.3 -0.2 -0.9 -1.4 -0.5 0.3 -0.1 -0.6 -0.5 -0.1 -0.4 0.2 0.3 -0.0 -0.4 0.2 -0.2 -0.9 0.0 0.2 0.1 -0.6
Unable to work because of sickness or disability 1.2 1.6 3.8 -1.0 -1.6 -1.3 -1.1 -1.5 -1.7 -1.4 -0.8 -1.2 -0.3 -1.5 -1.6 -0.1 0.2 -1.3 -1.4 -1.6 -1.5 0.3 -0.2 0.3 -1.0 0.6 -0.9 -1.0 -1.7 -0.4 -1.2 -1.5 -1.7 -1.4 -1.2 -1.8 0.0 -1.4 -1.6 -1.6 -1.6 -1.4 -1.9 -1.0 -1.2 -1.5 -1.6 -1.0
Commuting to job workplace: Cycle 2.6 3.1 6.9 1.7 2.5 1.8 1.7 1.7 2.3 1.9 -0.1 1.7 1.1 1.8 2.1 0.9 0.3 1.7 2.0 1.7 0.7 0.2 0.9 -0.9 1.3 -2.0 1.4 1.9 1.6 1.1 2.1 2.5 2.2 1.9 1.6 2.4 0.3 1.9 2.5 1.9 2.0 2.3 2.6 1.2 1.4 2.5 2.5 1.2
Myopia 0.7 1.0 3.3 1.8 1.2 -0.4 0.9 0.9 0.8 0.8 -1.6 -0.5 0.7 0.8 1.2 0.3 -0.4 -0.1 1.2 0.6 0.5 -0.5 1.6 -0.6 0.1 -1.4 0.3 -0.6 1.6 1.5 0.6 1.4 1.4 0.6 0.3 1.5 0.1 0.7 1.1 1.5 1.0 1.1 1.6 0.1 1.3 1.3 1.2 0.1
Vascular/heart problems diagnosed by doctor 1.6 4.5 12.5 -1.5 -2.0 -3.2 -3.1 -1.7 -2.2 -2.3 3.3 -1.5 0.5 -1.7 -1.7 -3.5 -0.8 -2.6 -1.7 -2.3 -0.7 -0.9 -2.7 0.5 -2.4 -0.0 -2.0 -0.9 -3.2 -0.2 -2.1 -2.2 -2.0 -2.4 -2.7 -1.9 -1.9 -2.2 -2.5 -1.4 -1.9 -2.9 -1.5 -2.0 -1.2 -2.3 -2.5 -2.6
Cholesterol lowering medication 0.3 0.5 3.0 0.3 0.7 0.4 0.7 0.1 0.9 0.2 0.3 1.4 -0.8 0.2 0.3 -0.6 -1.7 0.1 0.2 0.3 -0.5 -1.6 -0.2 -1.7 -0.1 -1.2 -0.9 -0.2 -0.2 -0.0 -0.3 0.8 0.5 0.2 0.2 0.9 -0.1 -0.5 0.6 0.3 0.2 0.5 1.5 0.0 -0.2 0.8 0.8 0.3
Medication: Omeprazole (e.g. Zanprol) 0.6 0.7 3.0 -0.1 -1.2 -0.5 -0.3 -0.5 -1.0 -0.7 1.7 0.1 0.9 -0.6 -0.9 -0.4 -1.0 -0.5 -0.5 -0.3 0.4 -1.0 1.0 0.2 -0.3 -1.0 -1.0 -1.5 -0.7 -0.3 -1.1 -1.4 -0.9 -0.7 -0.6 -0.9 0.1 -1.1 -1.2 -0.7 -0.8 -1.0 -0.9 -0.3 -0.7 -1.3 -1.2 -0.3
Pain experienced in last month 0.5 0.8 7.6 -0.8 -0.4 -0.3 -0.6 -0.2 -0.4 -0.3 2.8 -0.9 0.8 -0.1 -0.2 -2.0 -0.9 -0.1 -0.4 -0.3 -1.1 -1.1 -1.8 -0.8 -0.1 2.1 -0.8 0.8 -1.7 -1.7 -0.6 -0.6 -0.3 -0.2 -0.2 -0.1 -0.8 -0.5 -0.5 -0.4 -0.2 -0.8 0.3 0.1 -0.8 -0.6 -0.5 0.0
Supplements: Calcium 0.9 1.0 3.4 -0.7 -1.6 -0.1 -0.8 -0.9 -1.4 -1.2 0.2 -0.7 -0.5 -1.0 -1.2 0.3 0.0 -0.5 -1.2 -0.9 -0.2 0.2 0.1 0.8 -0.7 1.1 -0.4 -0.9 -0.3 -0.5 -1.5 -1.6 -1.3 -1.3 -0.8 -1.5 -0.1 -0.9 -1.6 -1.0 -1.1 -1.4 -1.9 -0.8 -0.6 -1.6 -1.5 -0.7
Basal cell carcinoma (self-reported) 3.3 4.0 9.9 2.4 1.2 1.9 2.7 2.5 2.1 2.4 1.6 3.1 2.0 2.5 2.1 2.1 -0.5 2.5 2.4 2.9 1.4 -0.6 2.7 -1.2 2.4 -1.9 1.1 2.4 0.8 1.1 2.3 1.3 1.9 2.4 2.1 1.9 2.0 1.2 1.3 1.7 2.3 1.5 1.7 2.6 1.7 1.4 1.5 2.1
Heart attack/myocardial infarction (self-reported) 1.4 1.8 11.1 -1.4 -0.8 -1.0 -0.8 -1.6 -1.4 -1.4 -3.3 -1.3 -2.7 -1.6 -1.5 -1.3 -0.7 -1.6 -1.6 -1.5 -1.3 -0.6 -1.2 0.6 -1.3 -0.0 -1.4 -1.7 -0.9 -0.3 -1.5 -0.9 -1.3 -1.3 -1.2 -1.1 -0.9 -1.4 -0.9 -1.4 -1.6 -0.9 -0.6 -1.3 -1.6 -0.9 -0.9 -1.1
Deep venous thrombosis (DVT) (self-reported) 0.9 1.2 3.3 -1.8 -0.6 -0.9 -1.5 -1.7 -0.7 -1.3 -0.8 0.5 -0.6 -1.6 -1.6 -0.7 0.8 -0.7 -1.5 -1.2 -0.4 1.0 -1.2 1.3 -1.0 -0.8 -0.3 -0.7 -0.2 -1.6 -1.0 -0.6 -1.4 -1.1 -0.7 -1.4 -1.3 -0.5 -0.6 -1.6 -1.5 -0.6 -1.2 -1.2 -1.6 -0.6 -0.6 -0.8
Heart disease (siblings) 0.5 0.6 6.3 0.4 0.9 -0.3 0.3 0.1 0.3 -0.0 -2.5 -0.8 -1.0 0.2 0.6 0.2 0.9 -0.2 0.2 -0.0 -1.2 0.8 0.0 -0.7 -0.7 0.1 0.7 0.3 1.2 2.2 0.5 0.7 0.7 -0.1 -0.6 0.6 -0.6 0.7 0.8 1.0 0.4 0.3 0.5 -0.7 0.8 0.6 0.3 -0.9
Alcohol drinker status: Previous 1.0 1.2 7.2 -0.5 -1.0 -0.9 -1.5 -0.9 -0.9 -0.9 2.2 -1.2 2.3 -0.9 -1.0 -0.9 0.4 -0.5 -0.7 -1.0 -1.3 0.5 0.4 1.6 -0.4 0.7 -0.1 -1.5 -1.3 -2.7 -0.6 -1.0 -1.2 -0.7 -0.5 -1.3 -0.6 -0.5 -0.9 -1.2 -0.9 -0.7 -1.3 -0.5 -0.6 -1.0 -0.9 -0.5
Pack years of smoking 0.3 0.5 1.8 0.8 -0.3 0.6 1.1 0.8 -0.1 0.7 -1.1 0.0 0.1 0.8 0.4 0.7 -0.7 0.5 0.7 0.7 0.6 -0.8 1.2 1.3 1.1 0.5 -0.1 -0.9 0.2 -0.4 0.6 -0.2 0.2 0.8 0.9 0.2 1.1 -0.2 -0.1 0.0 0.6 0.2 0.3 1.3 0.4 -0.1 0.1 1.0
Impedance of whole body 1.3 6.5 14.2 -2.3 -1.3 -3.0 -2.6 -2.8 -2.5 -3.1 -2.5 -3.5 -3.8 -2.7 -2.1 -2.2 0.3 -3.5 -2.7 -3.3 -3.2 0.3 -2.9 -0.6 -3.7 2.4 -1.7 -0.8 -2.6 0.5 -2.5 -1.7 -2.0 -3.3 -3.7 -1.9 -2.9 -1.9 -2.1 -1.4 -2.6 -3.0 -1.6 -3.4 -1.7 -1.9 -2.4 -3.7
Leg fat mass (left) 0.5 1.9 4.9 -1.8 -1.6 -0.4 -1.4 -1.5 -1.5 -1.5 0.2 -1.6 0.0 -1.7 -1.8 -0.6 1.0 -0.9 -1.6 -1.3 -0.2 1.1 -0.4 1.2 -0.9 2.2 -0.1 -1.5 -1.1 -1.7 -1.2 -1.7 -1.8 -1.5 -1.0 -2.0 -0.9 -0.7 -1.6 -1.8 -1.7 -1.6 -2.2 -1.1 -1.6 -1.6 -1.6 -0.9
Arm predicted mass (left) 0.8 4.1 10.1 -3.0 -2.2 -0.9 -2.2 -2.1 -2.5 -2.0 -1.0 -2.7 -0.5 -2.3 -2.6 -0.7 1.2 -1.2 -2.2 -2.0 0.2 1.4 -1.5 3.0 -0.8 2.8 -0.3 -3.2 -0.3 -3.0 -1.8 -2.3 -2.6 -1.7 -0.9 -2.9 -1.2 -0.9 -2.0 -2.7 -2.3 -1.8 -3.0 -1.2 -2.4 -2.2 -2.1 -0.8