[Hub]/) : Traits : Allergy :

chr15:40,778,506-42,749,023

Best TWAS P=1.69e-12 · Best GWAS P=2.71e-13 conditioned to 0.00149

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex EXD1 0.04 0.04 lasso 3 0.04 8.1e-06 -6.2 5.9 3.9e-09 0.64 0.65 0.31 FALSE
2 GTEx Artery Aorta OIP5-AS1 0.16 0.21 enet 26 0.23 5.2e-13 -4.5 -5.5 2.9e-08 -0.69 0.99 0.01 FALSE
3 GTEx Brain Cerebellum OIP5 0.16 0.09 lasso 4 0.16 1.8e-05 -3.9 -5.2 2.0e-07 -0.74 0.18 0.41 FALSE
4 GTEx Brain Cerebellum NDUFAF1 0.24 0.26 lasso 8 0.20 1.1e-06 -4.0 5.3 1.2e-07 0.59 0.64 0.34 FALSE
5 GTEx Brain Frontal Cortex BA9 OIP5 0.13 0.00 enet 16 0.01 2.1e-01 -1.9 -5.6 2.3e-08 -0.41 0.04 0.46 FALSE
6 GTEx Brain Frontal Cortex BA9 NUSAP1 0.39 0.42 enet 22 0.42 2.0e-12 -3.9 -5.2 1.7e-07 -0.68 0.90 0.10 FALSE
7 GTEx Brain Hippocampus NUSAP1 0.30 0.25 enet 14 0.26 1.0e-06 -3.9 -5.1 2.9e-07 -0.68 0.18 0.62 FALSE
8 GTEx Brain Hypothalamus NUSAP1 0.26 0.36 lasso 4 0.27 5.6e-07 -5.7 -5.4 6.7e-08 -0.64 0.41 0.51 FALSE
9 GTEx Brain Hypothalamus NDUFAF1 0.24 0.12 lasso 5 0.13 5.9e-04 -5.5 5.3 1.2e-07 0.61 0.08 0.69 FALSE
10 GTEx Brain Nucleus accumbens basal ganglia NDUFAF1 0.12 0.11 lasso 6 0.10 9.7e-04 -4.7 5.1 2.7e-07 0.60 0.32 0.16 FALSE
11 GTEx Breast Mammary Tissue OIP5-AS1 0.20 0.24 lasso 7 0.22 1.8e-11 -4.7 -5.4 5.5e-08 -0.71 0.92 0.08 FALSE
12 GTEx Breast Mammary Tissue (Male) OIP5-AS1 0.26 0.10 enet 20 0.22 7.3e-06 -4.5 -5.4 8.7e-08 -0.63 0.22 0.44 FALSE
13 GTEx Breast Mammary Tissue (Female) OIP5-AS1 0.28 0.31 lasso 3 0.29 3.0e-09 -4.7 -5.5 3.4e-08 -0.75 0.15 0.84 FALSE
14 GTEx Cells EBV-transformed lymphocytes NDUFAF1 0.35 0.46 enet 14 0.51 3.1e-19 -4.1 5.4 6.0e-08 0.63 1.00 0.00 FALSE
15 GTEx Cells Transformed fibroblasts NDUFAF1 0.26 0.15 lasso 8 0.20 2.8e-15 -5.5 5.5 3.8e-08 0.61 1.00 0.00 FALSE
16 GTEx Colon Sigmoid NDUFAF1 0.15 0.06 lasso 4 0.06 5.2e-03 -6.3 7.1 1.7e-12 0.73 0.12 0.71 TRUE
17 GTEx Esophagus Mucosa NDUFAF1 0.25 0.18 enet 26 0.24 4.3e-16 -6.3 5.9 3.7e-09 0.63 0.71 0.29 FALSE
18 GTEx Esophagus Mucosa CHP1 0.19 0.10 lasso 7 0.09 1.4e-06 -5.7 6.0 2.1e-09 0.75 0.54 0.46 FALSE
19 GTEx Lung OIP5-AS1 0.09 0.08 enet 14 0.12 2.8e-09 -6.3 -6.3 3.0e-10 -0.74 0.30 0.70 FALSE
20 GTEx Nerve Tibial NUSAP1 0.15 0.09 enet 10 0.15 9.8e-11 -3.8 -5.4 5.1e-08 -0.67 0.95 0.05 FALSE
21 GTEx Skin Not Sun Exposed Suprapubic NDUFAF1 0.16 0.06 lasso 3 0.07 1.7e-04 -6.3 5.5 3.6e-08 0.55 0.05 0.54 FALSE
22 GTEx Skin Sun Exposed Lower leg CHP1 0.06 0.04 enet 9 0.04 3.1e-04 -6.3 6.3 3.5e-10 0.69 0.31 0.42 FALSE
23 GTEx Thyroid RTF1 0.28 0.27 lasso 3 0.26 8.4e-20 6.4 6.6 5.7e-11 0.91 0.03 0.97 FALSE
24 NTR Blood RTF1 0.04 0.02 blup 338 0.03 6.9e-09 5.8 -5.9 4.0e-09 -0.68 0.19 0.81 FALSE
25 YFS Blood MGA 0.01 0.00 blup 454 0.00 7.1e-02 -4.8 -5.7 9.0e-09 -0.58 0.10 0.27 FALSE
26 The Cancer Genome Atlas Breast Invasive Carcinoma CHP 0.01 0.01 blup 54 0.01 1.4e-02 -6.4 6.3 2.5e-10 0.75 0.01 0.90 FALSE
27 The Cancer Genome Atlas Breast Invasive Carcinoma LOC729082 0.02 0.01 blup 44 0.02 2.9e-04 -4.9 5.1 2.8e-07 0.69 0.20 0.66 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma RTF1 0.04 0.02 lasso 3 0.02 4.0e-03 6.4 6.7 2.9e-11 0.91 0.00 0.98 FALSE