[Hub]/) : Traits : Height :

chr7:814,788-3,778,937

Best TWAS P=1.34e-246 · Best GWAS P=1.45e-248 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AMZ1 0.19 0.12 enet 22 0.13 5.7e-16 17.06 18.2 3.5e-74 -0.44 1.00 0.00 TRUE
2 CommonMind Brain Pre-frontal Cortex GNA12 0.06 0.00 bslmm 603 0.02 3.7e-03 -0.64 11.2 4.1e-29 -0.44 0.12 0.10 TRUE
3 GTEx Adipose Subcutaneous GNA12 0.11 0.08 lasso 4 0.07 1.3e-06 -23.32 -24.3 3.9e-130 0.73 0.64 0.36 FALSE
4 GTEx Adipose Subcutaneous ELFN1 0.06 0.04 lasso 3 0.02 9.5e-03 8.24 8.0 1.6e-15 -0.06 0.01 0.94 FALSE
5 GTEx Adipose Visceral Omentum GNA12 0.28 0.06 enet 46 0.08 8.0e-05 14.99 -9.6 6.3e-22 0.38 0.11 0.74 FALSE
6 GTEx Adrenal Gland GNA12 0.33 -0.01 enet 41 0.10 1.6e-04 2.00 -8.2 2.4e-16 0.22 0.06 0.29 FALSE
7 GTEx Artery Tibial GNA12 0.24 0.13 enet 20 0.22 3.5e-17 -33.67 -30.8 9.1e-209 0.87 0.01 0.99 FALSE
8 GTEx Brain Cortex FTSJ2 0.17 0.01 enet 16 0.06 1.1e-02 -3.08 -5.3 1.1e-07 0.00 0.11 0.06 FALSE
9 GTEx Breast Mammary Tissue (Male) EIF3B 0.38 -0.01 enet 28 0.12 1.3e-03 20.00 -5.9 3.2e-09 0.06 0.04 0.07 FALSE
10 GTEx Breast Mammary Tissue (Female) GNA12 0.10 -0.01 enet 16 0.00 4.5e-01 -0.68 -5.2 2.2e-07 0.14 0.04 0.24 FALSE
11 GTEx Cells EBV-transformed lymphocytes GNA12 0.46 0.51 lasso 5 0.50 7.9e-19 -32.55 -32.6 1.6e-232 0.92 0.60 0.40 FALSE
12 GTEx Cells Transformed fibroblasts GNA12 0.21 0.11 lasso 11 0.15 1.7e-11 -33.58 -28.2 1.1e-174 0.89 0.02 0.98 FALSE
13 GTEx Colon Sigmoid GNA12 0.14 0.05 lasso 3 0.03 3.6e-02 -22.74 -29.4 3.5e-190 0.84 0.02 0.92 FALSE
14 GTEx Colon Transverse GNA12 0.19 0.08 lasso 4 0.10 2.3e-05 19.87 -22.3 3.0e-110 0.64 0.25 0.73 FALSE
15 GTEx Esophagus Gastroesophageal Junction GNA12 0.20 0.12 lasso 6 0.12 3.4e-05 -23.32 -29.1 3.3e-186 0.85 0.05 0.93 FALSE
16 GTEx Esophagus Mucosa GNA12 0.16 0.13 lasso 3 0.13 3.0e-09 -32.60 -31.1 1.1e-212 0.89 0.01 0.99 FALSE
17 GTEx Esophagus Muscularis MAD1L1 0.22 0.01 enet 40 0.05 5.6e-04 -1.97 -5.7 1.2e-08 -0.03 0.18 0.13 FALSE
18 GTEx Esophagus Muscularis GNA12 0.32 0.31 lasso 3 0.34 2.1e-21 -33.67 -32.9 2.2e-237 0.98 0.00 1.00 FALSE
19 GTEx Esophagus Muscularis AC004840.9 0.19 0.07 enet 34 0.10 1.2e-06 -2.75 5.6 1.8e-08 -0.23 0.47 0.06 TRUE
20 GTEx Liver AC004840.9 0.27 0.01 enet 27 0.06 7.0e-03 1.82 17.1 9.5e-66 -0.37 0.07 0.19 FALSE
21 GTEx Lung SNX8 0.14 0.01 lasso 6 0.04 4.1e-04 -3.28 8.8 1.1e-18 -0.29 0.25 0.14 FALSE
22 GTEx Lung GNA12 0.16 0.08 enet 21 0.12 1.2e-09 -32.51 -27.8 4.2e-170 0.77 0.02 0.98 TRUE
23 GTEx Nerve Tibial GNA12 0.31 0.34 lasso 7 0.36 9.6e-27 -23.11 -28.8 4.9e-182 0.85 0.86 0.14 FALSE
24 GTEx Pituitary INTS1 0.29 0.33 enet 8 0.20 9.1e-06 5.82 5.2 1.6e-07 -0.09 0.44 0.33 FALSE
25 GTEx Prostate MAFK 0.43 -0.01 enet 22 0.01 1.8e-01 8.12 -8.1 6.0e-16 0.02 0.02 0.57 TRUE
26 GTEx Skin Not Sun Exposed Suprapubic GNA12 0.10 0.15 lasso 3 0.12 4.2e-07 14.99 -17.3 2.7e-67 0.53 0.34 0.64 FALSE
27 GTEx Skin Sun Exposed Lower leg GNA12 0.17 0.16 lasso 3 0.18 1.3e-14 -22.48 -28.8 6.5e-182 0.88 0.07 0.93 FALSE
28 GTEx Skin Sun Exposed Lower leg AC004840.9 0.18 0.01 enet 36 0.02 3.7e-03 6.17 -9.8 7.8e-23 0.13 0.20 0.13 TRUE
29 GTEx Small Intestine Terminal Ileum GNA12 0.34 0.20 lasso 5 0.16 2.4e-04 -22.78 -23.5 2.0e-122 0.73 0.07 0.77 FALSE
30 GTEx Stomach GNA12 0.18 0.16 lasso 2 0.13 6.6e-07 -22.74 -22.8 4.0e-115 0.68 0.76 0.23 FALSE
31 GTEx Testis IQCE 0.47 0.00 enet 19 0.14 8.9e-07 -4.31 -5.3 9.3e-08 0.16 0.15 0.18 TRUE
32 GTEx Thyroid AC004840.9 0.11 0.10 enet 25 0.13 4.3e-10 -2.75 -5.7 1.4e-08 0.07 0.89 0.00 FALSE
33 GTEx Uterus INTS1 0.47 0.07 enet 22 0.05 4.1e-02 5.75 6.8 1.2e-11 -0.08 0.03 0.62 FALSE
34 GTEx Whole Blood GNA12 0.09 0.01 enet 4 0.00 3.3e-01 -32.17 -32.4 2.4e-230 0.95 0.02 0.91 FALSE
35 METSIM Adipose CARD11 0.05 0.01 blup 642 0.03 2.0e-05 1.57 5.4 8.4e-08 -0.19 0.40 0.03 FALSE
36 METSIM Adipose GNA12 0.07 0.05 lasso 3 0.05 3.3e-08 -22.78 -23.2 4.8e-119 0.74 0.28 0.72 FALSE
37 NTR Blood GNA12 0.07 0.03 bslmm 597 0.06 1.3e-17 -22.64 -20.6 3.5e-94 0.63 0.91 0.09 FALSE
38 ROSMAP Brain Pre-frontal Cortex SNX8 0.09 0.04 blup 452 0.05 1.2e-06 2.91 -6.7 1.8e-11 0.10 0.93 0.00 TRUE
39 ROSMAP Brain Pre-frontal Cortex GNA12 0.13 0.08 bslmm 585 0.08 5.3e-11 10.23 -5.8 6.8e-09 0.11 1.00 0.00 FALSE
40 ROSMAP Brain Pre-frontal Cortex AMZ1 0.09 0.05 lasso 6 0.04 2.4e-06 -33.67 33.5 1.3e-246 -0.95 0.00 1.00 TRUE
41 YFS Blood CHST12 0.04 0.00 enet 25 0.02 1.0e-06 -1.64 7.5 4.9e-14 -0.15 0.04 0.04 TRUE
42 YFS Blood GNA12 0.23 0.15 bslmm 570 0.25 4.5e-82 11.40 -18.1 2.1e-73 0.51 1.00 0.00 FALSE
43 YFS Blood SNX8 0.03 0.00 blup 442 0.02 6.6e-06 1.68 -5.5 2.9e-08 0.14 0.44 0.02 TRUE
44 YFS Blood TTYH3 0.02 0.01 lasso 4 0.01 2.6e-04 3.54 5.6 2.4e-08 -0.17 0.61 0.01 FALSE
45 The Cancer Genome Atlas Bladder Urothelial Carcinoma TMEM184A 0.03 0.01 lasso 2 0.02 1.5e-02 8.15 8.0 1.9e-15 -0.05 0.01 0.73 FALSE
46 The Cancer Genome Atlas Breast Invasive Carcinoma TMEM184A 0.02 0.03 lasso 2 0.02 1.7e-05 6.35 7.2 8.9e-13 -0.05 0.02 0.98 FALSE
47 The Cancer Genome Atlas Colon Adenocarcinoma GNA12 0.09 0.00 blup 103 0.03 9.3e-03 -23.11 -14.7 4.5e-49 0.51 0.04 0.12 FALSE
48 The Cancer Genome Atlas Colon Adenocarcinoma TMEM184A 0.12 0.16 lasso 4 0.15 4.8e-09 7.79 7.8 9.5e-15 -0.05 0.03 0.97 FALSE
49 The Cancer Genome Atlas Esophageal Carcinoma AMZ1 0.18 0.05 blup 69 0.05 1.4e-02 18.79 -27.1 3.5e-161 0.74 0.01 0.71 FALSE
50 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GNA12 0.03 0.04 lasso 1 0.04 3.0e-05 -23.32 -23.3 3.1e-120 0.70 0.08 0.76 FALSE
51 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma AMZ1 0.33 0.20 lasso 3 0.19 4.5e-11 6.85 6.6 3.5e-11 -0.26 1.00 0.00 FALSE
52 The Cancer Genome Atlas Brain Lower Grade Glioma AMZ1 0.04 0.04 lasso 3 0.02 1.3e-03 18.79 22.2 7.0e-109 -0.64 0.03 0.91 FALSE
53 The Cancer Genome Atlas Lung Adenocarcinoma GNA12 0.03 0.01 enet 7 0.02 1.5e-03 16.70 -28.0 9.3e-173 0.78 0.07 0.69 FALSE
54 The Cancer Genome Atlas Lung Squamous Cell Carcinoma AMZ1 0.14 0.06 enet 15 0.06 7.4e-08 6.85 12.6 4.0e-36 -0.33 0.84 0.04 FALSE
55 The Cancer Genome Atlas Pancreatic Adenocarcinoma AMZ1 0.17 0.11 enet 9 0.10 5.0e-05 6.85 14.9 2.1e-50 -0.47 0.05 0.46 FALSE
56 The Cancer Genome Atlas Pancreatic Adenocarcinoma INTS1 0.07 0.00 blup 46 0.01 1.8e-01 5.75 5.3 1.5e-07 -0.05 0.02 0.36 FALSE
57 The Cancer Genome Atlas Prostate Adenocarcinoma AMZ1 0.08 0.01 blup 71 0.05 1.3e-05 -23.32 19.2 2.7e-82 -0.64 0.06 0.71 FALSE
58 The Cancer Genome Atlas Prostate Adenocarcinoma TMEM184A 0.06 0.10 lasso 4 0.10 3.1e-10 8.15 7.8 5.0e-15 -0.04 0.01 0.99 FALSE
59 The Cancer Genome Atlas Thyroid Carcinoma AMZ1 0.32 0.04 enet 19 0.20 3.3e-19 -22.64 17.6 1.5e-69 -0.56 0.19 0.81 TRUE