[Hub]/) : Traits : Height :

chr10:27,265,641-33,021,290

Best TWAS P=1.32e-32 · Best GWAS P=4.95e-29 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous WAC-AS1 0.39 0.46 lasso 5 0.45 1.1e-40 9.7 9.0 1.6e-19 0.91 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum WAC-AS1 0.21 0.17 enet 16 0.18 2.0e-09 9.6 8.8 1.7e-18 0.88 0.04 0.96 FALSE
3 GTEx Adrenal Gland WAC-AS1 0.28 0.19 lasso 4 0.14 7.2e-06 9.7 9.5 1.8e-21 0.91 0.07 0.91 FALSE
4 GTEx Artery Aorta ARHGAP12 0.14 0.03 lasso 5 0.05 1.2e-03 -3.5 -5.7 1.0e-08 0.00 0.02 0.79 FALSE
5 GTEx Artery Aorta WAC-AS1 0.39 0.38 lasso 6 0.38 3.1e-22 9.7 8.8 1.4e-18 0.90 0.98 0.02 FALSE
6 GTEx Artery Coronary WAC-AS1 0.41 0.21 lasso 6 0.19 4.0e-07 9.7 9.8 1.0e-22 0.90 0.15 0.84 FALSE
7 GTEx Artery Tibial WAC 0.10 0.00 enet 32 0.00 5.6e-01 -7.9 -5.3 9.0e-08 -0.37 0.08 0.15 FALSE
8 GTEx Artery Tibial WAC-AS1 0.44 0.43 lasso 4 0.44 4.0e-37 9.7 8.9 3.6e-19 0.90 1.00 0.00 FALSE
9 GTEx Brain Hippocampus WAC-AS1 0.29 0.01 enet 10 -0.01 8.5e-01 9.8 9.6 1.1e-21 0.81 0.04 0.56 FALSE
10 GTEx Brain Nucleus accumbens basal ganglia WAC-AS1 0.38 0.07 enet 11 0.08 4.3e-03 9.7 6.1 9.4e-10 0.74 0.05 0.71 FALSE
11 GTEx Breast Mammary Tissue WAC-AS1 0.29 0.32 lasso 2 0.31 2.1e-16 9.7 9.7 2.8e-22 0.91 0.40 0.60 FALSE
12 GTEx Breast Mammary Tissue (Female) WAC-AS1 0.30 0.30 enet 13 0.33 1.7e-10 9.7 8.6 6.4e-18 0.91 0.18 0.82 FALSE
13 GTEx Cells EBV-transformed lymphocytes KIF5B 0.17 0.10 lasso 6 0.05 1.0e-02 -5.9 -6.3 2.9e-10 -0.04 0.07 0.44 TRUE
14 GTEx Cells EBV-transformed lymphocytes WAC-AS1 0.45 0.36 enet 12 0.41 1.1e-14 9.7 8.4 6.4e-17 0.85 0.07 0.93 FALSE
15 GTEx Cells Transformed fibroblasts KIAA1462 0.36 0.26 lasso 6 0.25 1.6e-18 -6.7 -6.7 2.9e-11 -0.01 0.02 0.98 TRUE
16 GTEx Cells Transformed fibroblasts WAC-AS1 0.58 0.62 lasso 12 0.64 9.7e-62 9.7 9.5 2.8e-21 0.92 0.97 0.03 FALSE
17 GTEx Colon Sigmoid WAC-AS1 0.36 0.23 lasso 9 0.22 2.6e-08 9.7 9.1 7.0e-20 0.88 0.39 0.60 FALSE
18 GTEx Colon Transverse WAC-AS1 0.36 0.17 enet 16 0.31 3.6e-15 6.6 7.2 5.9e-13 0.76 0.20 0.80 FALSE
19 GTEx Esophagus Gastroesophageal Junction WAC-AS1 0.37 0.16 lasso 6 0.20 9.1e-08 11.2 9.6 5.2e-22 0.91 0.02 0.98 FALSE
20 GTEx Esophagus Mucosa WAC-AS1 0.52 0.44 lasso 16 0.51 1.2e-38 9.7 7.9 2.4e-15 0.86 0.72 0.28 FALSE
21 GTEx Esophagus Muscularis WAC-AS1 0.37 0.29 enet 32 0.38 5.5e-24 9.7 7.6 2.7e-14 0.80 0.09 0.91 FALSE
22 GTEx Heart Atrial Appendage WAC-AS1 0.18 0.12 enet 6 0.15 2.5e-07 9.7 9.2 2.5e-20 0.85 0.20 0.79 FALSE
23 GTEx Heart Left Ventricle WAC-AS1 0.39 0.08 lasso 8 0.20 1.3e-10 6.6 5.9 3.4e-09 0.67 0.12 0.88 FALSE
24 GTEx Liver WAC-AS1 0.37 0.34 lasso 3 0.34 3.1e-10 9.7 9.7 2.7e-22 0.90 0.08 0.92 FALSE
25 GTEx Lung WAC-AS1 0.32 0.13 enet 26 0.24 4.7e-18 9.7 8.6 1.2e-17 0.86 0.03 0.97 FALSE
26 GTEx Muscle Skeletal WAC-AS1 0.29 0.15 enet 26 0.22 8.7e-21 6.6 5.4 5.8e-08 0.70 0.59 0.41 FALSE
27 GTEx Nerve Tibial WAC-AS1 0.45 0.55 lasso 5 0.56 1.4e-46 9.7 9.4 3.5e-21 0.92 1.00 0.00 FALSE
28 GTEx Pancreas WAC-AS1 0.45 0.33 lasso 8 0.34 6.4e-15 9.6 9.3 1.7e-20 0.92 0.08 0.92 FALSE
29 GTEx Skin Not Sun Exposed Suprapubic KIF5B 0.15 0.03 enet 12 0.05 6.5e-04 -3.2 -5.3 1.5e-07 0.08 0.28 0.04 FALSE
30 GTEx Skin Not Sun Exposed Suprapubic WAC-AS1 0.48 0.48 enet 37 0.56 6.1e-37 9.7 7.9 3.2e-15 0.86 0.44 0.56 FALSE
31 GTEx Skin Sun Exposed Lower leg WAC-AS1 0.34 0.39 enet 21 0.45 7.7e-41 9.7 7.5 9.0e-14 0.86 1.00 0.00 FALSE
32 GTEx Stomach WAC-AS1 0.39 0.31 lasso 8 0.33 1.1e-16 9.7 8.7 2.8e-18 0.89 0.06 0.94 FALSE
33 GTEx Testis WAC 0.23 0.05 enet 11 0.09 1.3e-04 -4.4 -6.5 1.1e-10 -0.30 0.60 0.02 FALSE
34 GTEx Testis WAC-AS1 0.45 0.47 lasso 3 0.48 4.3e-24 9.7 9.7 2.2e-22 0.91 0.98 0.02 FALSE
35 GTEx Thyroid WAC-AS1 0.21 0.13 enet 12 0.20 1.6e-15 9.7 7.0 2.9e-12 0.86 0.32 0.68 FALSE
36 GTEx Vagina WAC-AS1 0.55 0.25 lasso 5 0.22 1.0e-05 9.7 10.7 1.0e-26 0.85 0.05 0.92 FALSE
37 METSIM Adipose ARHGAP12 0.04 0.03 lasso 2 0.02 2.6e-04 5.5 -5.4 5.3e-08 0.04 0.31 0.06 FALSE
38 METSIM Adipose MKX 0.08 0.10 lasso 5 0.09 2.4e-13 6.9 -7.0 3.6e-12 -0.04 1.00 0.00 TRUE
39 ROSMAP Brain Pre-frontal Cortex BAMBI 0.07 0.05 lasso 3 0.04 2.8e-06 5.7 6.2 5.2e-10 0.54 0.93 0.04 FALSE
40 ROSMAP Brain Pre-frontal Cortex WAC 0.21 0.29 lasso 5 0.29 5.9e-37 11.1 11.4 5.1e-30 0.99 0.01 0.99 FALSE
41 ROSMAP Brain Pre-frontal Cortex KIF5B 0.06 0.02 lasso 2 0.03 5.6e-05 -3.9 5.2 2.5e-07 0.00 0.21 0.22 FALSE
42 ROSMAP Brain Pre-frontal Cortex WAC-AS1 0.39 0.35 bslmm 570 0.49 1.8e-72 6.6 5.9 3.6e-09 0.68 1.00 0.00 FALSE
43 YFS Blood WAC 0.06 0.08 bslmm 649 0.08 2.2e-24 11.0 -10.9 1.5e-27 -0.99 0.01 0.99 FALSE
44 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ZNF438 0.10 0.04 lasso 5 0.04 5.9e-05 3.1 5.1 3.1e-07 0.01 0.25 0.28 FALSE
45 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ZNF438 0.04 0.02 lasso 5 0.03 6.8e-04 -6.5 6.6 5.3e-11 -0.01 0.07 0.60 TRUE
46 The Cancer Genome Atlas Brain Lower Grade Glioma ZNF438 0.09 0.03 enet 10 0.03 7.1e-05 2.0 5.2 2.0e-07 -0.01 0.52 0.06 FALSE
47 The Cancer Genome Atlas Lung Adenocarcinoma ZNF438 0.07 0.03 lasso 5 0.04 1.9e-05 4.1 6.3 2.1e-10 0.01 0.01 0.99 FALSE
48 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma WAC 0.11 0.04 blup 83 0.07 1.3e-03 11.2 8.8 1.1e-18 0.91 0.01 0.87 FALSE
49 The Cancer Genome Atlas Prostate Adenocarcinoma WAC 0.07 0.02 blup 83 0.06 8.7e-07 1.5 7.8 8.1e-15 0.76 0.04 0.95 FALSE
50 The Cancer Genome Atlas Thyroid Carcinoma WAC 0.06 0.04 lasso 3 0.03 4.2e-04 11.1 11.9 1.3e-32 0.98 0.01 0.94 TRUE