[Hub]/) : Traits : Height :

chr1:31,188,089-34,592,020

Best TWAS P=1.75e-42 · Best GWAS P=2.83e-43 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MTMR9LP 0.11 0.11 lasso 23 0.11 6.5e-13 4.38 5.2 1.6e-07 0.34 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex PEF1 0.04 0.04 lasso 4 0.03 2.8e-04 -6.09 6.1 8.4e-10 0.04 0.84 0.04 FALSE
3 CommonMind Brain Pre-frontal Cortex TMEM54 0.05 0.00 blup 281 0.02 4.5e-03 -0.78 -5.5 4.7e-08 -0.07 0.10 0.30 FALSE
4 CommonMind Brain Pre-frontal Cortex TXLNA 0.04 0.04 bslmm 221 0.03 1.8e-04 8.48 -6.5 6.3e-11 -0.20 0.84 0.01 FALSE
5 CommonMind Brain Pre-frontal Cortex ZNF362 0.05 0.06 lasso 1 0.06 2.2e-07 -8.30 -8.3 1.1e-16 -0.09 0.00 1.00 TRUE
6 GTEx Artery Aorta PEF1 0.15 0.05 lasso 5 0.04 2.2e-03 -9.54 10.6 2.2e-26 0.10 0.51 0.02 TRUE
7 GTEx Artery Tibial PEF1 0.10 0.09 enet 16 0.09 9.0e-08 -6.10 6.7 2.4e-11 0.06 0.99 0.00 FALSE
8 GTEx Brain Caudate basal ganglia FAM167B 0.43 0.00 lasso 11 0.00 3.0e-01 -1.35 6.4 1.8e-10 0.34 0.02 0.21 FALSE
9 GTEx Brain Cerebellum RP11-415J8.3 0.25 0.06 lasso 3 0.07 4.2e-03 7.61 -7.4 1.1e-13 -0.11 0.13 0.14 FALSE
10 GTEx Breast Mammary Tissue SYNC 0.20 0.00 lasso 4 0.01 6.9e-02 -1.87 5.8 8.4e-09 0.15 0.14 0.24 FALSE
11 GTEx Cells EBV-transformed lymphocytes KPNA6 0.19 0.14 enet 18 0.10 4.9e-04 8.46 8.9 7.5e-19 0.36 0.22 0.05 FALSE
12 GTEx Cells EBV-transformed lymphocytes PHC2 0.58 0.34 lasso 7 0.28 7.3e-10 -7.89 7.3 2.1e-13 0.10 0.02 0.98 FALSE
13 GTEx Cells Transformed fibroblasts KPNA6 0.13 0.10 lasso 5 0.11 1.3e-08 8.44 8.4 3.0e-17 0.38 1.00 0.00 FALSE
14 GTEx Colon Sigmoid PEF1 0.16 0.09 lasso 3 0.09 4.3e-04 -7.19 8.7 3.3e-18 0.06 0.21 0.05 FALSE
15 GTEx Esophagus Mucosa MTMR9LP 0.07 0.09 lasso 3 0.05 1.5e-04 4.50 5.6 2.0e-08 0.35 0.73 0.10 TRUE
16 GTEx Nerve Tibial TXLNA 0.10 0.00 enet 5 0.00 6.8e-01 -2.71 -6.9 5.4e-12 -0.32 0.04 0.04 TRUE
17 GTEx Skin Not Sun Exposed Suprapubic EIF3I 0.12 0.06 lasso 1 0.03 7.2e-03 8.41 -8.4 4.1e-17 -0.38 0.09 0.04 FALSE
18 GTEx Skin Sun Exposed Lower leg PEF1 0.05 0.03 enet 9 0.02 4.6e-03 -9.54 8.0 1.5e-15 0.10 0.66 0.01 FALSE
19 GTEx Testis RP4-622L5.7 0.12 0.11 lasso 5 0.08 2.3e-04 8.48 8.5 1.8e-17 0.38 0.35 0.13 FALSE
20 GTEx Whole Blood SERINC2 0.34 0.14 enet 54 0.15 1.1e-13 -2.57 6.0 2.7e-09 0.12 1.00 0.00 TRUE
21 METSIM Adipose KPNA6 0.07 0.06 lasso 10 0.06 1.8e-09 8.50 8.8 8.8e-19 0.40 1.00 0.00 FALSE
22 METSIM Adipose PEF1 0.03 0.02 enet 17 0.02 7.9e-04 -6.39 5.2 2.4e-07 0.17 0.42 0.03 FALSE
23 ROSMAP Brain Pre-frontal Cortex KPNA6 0.03 0.04 lasso 4 0.02 8.1e-04 8.34 8.7 2.4e-18 0.42 0.61 0.20 TRUE
24 ROSMAP Brain Pre-frontal Cortex PHC2 0.11 0.07 lasso 3 0.05 2.2e-07 -7.89 -7.5 9.7e-14 -0.09 0.01 0.99 FALSE
25 ROSMAP Brain Pre-frontal Cortex PEF1 0.04 0.04 lasso 3 0.02 4.2e-04 -6.53 6.1 1.2e-09 0.06 0.82 0.01 FALSE
26 YFS Blood KPNA6 0.03 0.03 bslmm 236 0.04 1.1e-11 8.62 9.5 1.7e-21 0.40 1.00 0.00 FALSE
27 YFS Blood PEF1 0.05 0.02 blup 346 0.03 2.8e-11 -7.19 5.2 1.7e-07 0.06 1.00 0.00 FALSE
28 The Cancer Genome Atlas Breast Invasive Carcinoma ZNF362 0.03 0.01 blup 49 0.01 1.3e-03 2.72 -5.3 1.3e-07 -0.05 0.01 0.31 FALSE
29 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM39B 0.04 0.03 blup 16 0.03 5.0e-04 8.50 -8.2 2.5e-16 -0.31 0.01 0.94 FALSE
30 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MTMR9L 0.03 0.03 blup 28 0.01 1.6e-02 4.65 7.6 2.1e-14 0.39 0.04 0.55 FALSE
31 The Cancer Genome Atlas Brain Lower Grade Glioma KPNA6 0.02 0.02 blup 29 0.02 1.9e-03 8.49 8.4 3.0e-17 0.36 0.02 0.83 FALSE
32 The Cancer Genome Atlas Brain Lower Grade Glioma MTMR9L 0.04 0.04 blup 29 0.02 1.0e-03 4.50 7.0 2.3e-12 0.40 0.20 0.45 TRUE
33 The Cancer Genome Atlas Lung Adenocarcinoma MTMR9L 0.03 0.00 blup 30 0.01 1.0e-02 4.38 7.4 1.2e-13 0.32 0.01 0.60 FALSE
34 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TMEM39B 0.05 0.04 enet 9 0.05 1.7e-04 8.49 -6.6 4.0e-11 -0.22 0.01 0.82 FALSE
35 The Cancer Genome Atlas Skin Cutaneous Melanoma MTMR9L 0.15 0.02 blup 29 0.09 2.8e-03 4.77 7.4 1.8e-13 0.35 0.01 0.38 FALSE
36 The Cancer Genome Atlas Testicular Germ Cell Tumors PTP4A2 0.09 -0.01 blup 26 0.00 4.1e-01 10.66 13.7 1.8e-42 0.80 0.01 0.56 TRUE
37 The Cancer Genome Atlas Thyroid Carcinoma FAM167B 0.03 0.01 blup 26 0.02 2.4e-03 4.65 -6.7 1.7e-11 -0.37 0.02 0.74 FALSE
38 The Cancer Genome Atlas Thyroid Carcinoma KPNA6 0.03 0.03 blup 28 0.03 5.3e-04 8.62 8.5 1.4e-17 0.34 0.02 0.88 TRUE
39 The Cancer Genome Atlas Thyroid Carcinoma MTMR9L 0.03 0.04 blup 28 0.03 3.3e-04 4.38 7.6 3.7e-14 0.38 0.03 0.92 TRUE
40 The Cancer Genome Atlas Thyroid Carcinoma SPOCD1 0.04 0.02 blup 38 0.02 3.0e-03 -4.85 5.9 3.6e-09 0.34 0.04 0.11 FALSE
41 The Cancer Genome Atlas Thyroid Carcinoma TINAGL1 0.05 0.03 enet 5 0.03 1.2e-03 -6.53 -5.5 3.2e-08 -0.08 0.01 0.23 FALSE