[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr3:10,617,048-13,608,348

Best TWAS P=4.1e-29 · Best GWAS P=2.96e-36 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	TIMP4	0.11	0.05	bslmm	508	0.06	6.8e-08	5.37	6.8	1.4e-11	0.13	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	MKRN2	0.13	0.04	enet	10	0.07	3.2e-06	-6.87	-6.2	7.1e-10	-0.20	0.88	0.01	FALSE
3	GTEx	Adipose Visceral Omentum	MKRN2	0.20	0.05	enet	11	0.09	1.7e-05	-4.97	-6.9	6.8e-12	-0.18	0.87	0.01	TRUE
4	GTEx	Artery Aorta	MKRN2	0.30	0.07	enet	15	0.15	1.2e-08	-8.03	-7.1	1.3e-12	-0.21	0.98	0.00	FALSE
5	GTEx	Artery Aorta	TSEN2	0.11	0.01	enet	22	0.02	1.7e-02	3.92	8.4	3.1e-17	0.14	0.40	0.05	FALSE
6	GTEx	Artery Tibial	MKRN2	0.27	0.09	enet	20	0.25	3.1e-19	-6.87	-9.0	2.8e-19	-0.26	1.00	0.00	FALSE
7	GTEx	Artery Tibial	TSEN2	0.14	0.10	lasso	6	0.07	5.3e-06	-7.48	7.8	8.8e-15	0.26	0.99	0.00	FALSE
8	GTEx	Artery Tibial	TIMP4	0.20	0.24	lasso	2	0.24	1.7e-18	6.43	6.4	1.3e-10	0.11	1.00	0.00	FALSE
9	GTEx	Artery Tibial	SYN2	0.30	0.32	lasso	2	0.31	1.0e-24	6.43	6.4	1.8e-10	0.11	1.00	0.00	FALSE
10	GTEx	Brain Hypothalamus	TIMP4	0.24	0.10	lasso	4	0.11	1.7e-03	6.03	6.9	6.6e-12	0.20	0.19	0.46	TRUE
11	GTEx	Breast Mammary Tissue	TIMP4	0.17	0.06	lasso	5	0.07	1.9e-04	5.35	5.3	8.9e-08	0.15	0.45	0.03	TRUE
12	GTEx	Breast Mammary Tissue (Male)	TIMP4	0.11	-0.01	enet	24	-0.01	4.4e-01	5.35	5.6	2.3e-08	0.20	0.05	0.06	FALSE
13	GTEx	Cells EBV-transformed lymphocytes	PPARG	0.23	0.09	lasso	12	0.07	2.1e-03	5.09	6.2	5.8e-10	0.24	0.45	0.03	FALSE
14	GTEx	Cells EBV-transformed lymphocytes	TSEN2	0.48	0.27	lasso	12	0.26	6.3e-09	3.92	5.7	1.5e-08	0.03	0.94	0.01	FALSE
15	GTEx	Cells Transformed fibroblasts	MKRN2	0.18	0.16	lasso	6	0.16	8.8e-12	-6.49	-8.1	7.0e-16	-0.15	1.00	0.00	TRUE
16	GTEx	Cells Transformed fibroblasts	CAND2	0.34	0.08	lasso	14	0.13	8.1e-10	-0.95	-6.4	2.1e-10	-0.31	0.94	0.00	TRUE
17	GTEx	Cells Transformed fibroblasts	TSEN2	0.34	0.21	lasso	8	0.23	1.5e-17	3.92	5.5	3.3e-08	0.07	1.00	0.00	FALSE
18	GTEx	Esophagus Gastroesophageal Junction	MKRN2	0.17	0.10	enet	13	0.07	1.9e-03	-7.66	-8.9	8.0e-19	-0.17	0.29	0.04	FALSE
19	GTEx	Esophagus Gastroesophageal Junction	SYN2	0.23	0.09	lasso	4	0.12	3.3e-05	4.61	5.7	1.3e-08	0.19	0.86	0.01	FALSE
20	GTEx	Esophagus Mucosa	ATG7	0.12	0.04	enet	10	0.05	2.2e-04	-3.16	6.4	2.1e-10	-0.02	0.29	0.53	FALSE
21	GTEx	Esophagus Muscularis	MKRN2	0.15	0.05	lasso	8	0.12	8.9e-08	6.85	-6.3	3.2e-10	-0.24	0.97	0.00	TRUE
22	GTEx	Esophagus Muscularis	TSEN2	0.12	0.03	enet	36	0.05	5.6e-04	-7.33	9.6	7.2e-22	0.35	0.11	0.10	FALSE
23	GTEx	Heart Atrial Appendage	MKRN2	0.14	0.09	lasso	3	0.08	1.5e-04	-6.54	-7.3	3.8e-13	-0.10	0.75	0.01	FALSE
24	GTEx	Heart Left Ventricle	MKRN2	0.21	0.05	enet	15	0.14	1.1e-07	-4.97	-11.2	4.1e-29	-0.27	0.94	0.01	TRUE
25	GTEx	Heart Left Ventricle	SYN2	0.15	0.14	lasso	7	0.11	3.0e-06	0.71	5.1	3.1e-07	0.41	0.74	0.22	FALSE
26	GTEx	Lung	MKRN2	0.11	0.06	lasso	7	0.06	1.7e-05	-6.87	-7.7	1.1e-14	-0.17	0.86	0.00	FALSE
27	GTEx	Lung	SYN2	0.19	0.12	lasso	6	0.12	2.1e-09	4.79	5.4	5.3e-08	0.17	1.00	0.00	FALSE
28	GTEx	Muscle Skeletal	MKRN2	0.38	0.33	enet	14	0.39	1.7e-40	-6.49	-7.6	4.1e-14	-0.18	1.00	0.00	FALSE
29	GTEx	Muscle Skeletal	CAND2	0.34	0.29	lasso	5	0.31	1.0e-30	5.75	-6.0	2.7e-09	-0.12	1.00	0.00	TRUE
30	GTEx	Nerve Tibial	CAND2	0.12	0.01	enet	8	0.03	4.9e-03	5.74	6.5	7.6e-11	0.13	0.29	0.10	FALSE
31	GTEx	Nerve Tibial	SYN2	0.11	0.11	lasso	2	0.08	1.5e-06	5.56	6.0	2.0e-09	0.11	1.00	0.00	FALSE
32	GTEx	Spleen	SYN2	0.34	0.20	lasso	3	0.21	5.4e-06	5.37	5.5	2.8e-08	0.10	0.24	0.21	FALSE
33	GTEx	Testis	SYN2	0.26	0.16	lasso	7	0.17	4.2e-08	4.76	5.2	1.6e-07	0.13	0.94	0.02	FALSE
34	GTEx	Thyroid	MKRN2	0.11	0.04	enet	14	0.05	6.3e-05	-7.43	-9.6	9.5e-22	-0.26	0.77	0.13	FALSE
35	GTEx	Thyroid	CAND2	0.23	0.07	lasso	4	0.09	1.2e-07	5.78	5.9	3.4e-09	0.09	1.00	0.00	FALSE
36	GTEx	Thyroid	ATG7	0.11	0.02	lasso	3	0.02	1.1e-02	-3.16	5.2	2.1e-07	-0.05	0.09	0.59	FALSE
37	METSIM	Adipose	TSEN2	0.06	0.02	enet	30	0.06	9.3e-10	-7.74	11.0	3.6e-28	0.42	0.93	0.06	FALSE
38	NTR	Blood	TSEN2	0.02	0.00	bslmm	481	0.01	1.4e-03	-6.87	7.7	1.2e-14	0.14	0.30	0.01	FALSE
39	ROSMAP	Brain Pre-frontal Cortex	MKRN2	0.16	0.05	lasso	10	0.08	1.8e-10	-5.87	-8.2	1.9e-16	-0.31	1.00	0.00	FALSE
40	ROSMAP	Brain Pre-frontal Cortex	VGLL4	0.05	0.03	blup	422	0.04	3.7e-06	5.44	5.9	3.3e-09	-0.01	0.95	0.00	TRUE
41	ROSMAP	Brain Pre-frontal Cortex	TIMP4	0.07	0.05	lasso	7	0.06	5.5e-08	4.65	6.5	6.0e-11	0.17	1.00	0.00	FALSE
42	YFS	Blood	MKRN2	0.25	0.16	enet	16	0.18	7.2e-57	-6.49	-8.6	9.4e-18	-0.26	1.00	0.00	FALSE
43	YFS	Blood	RAF1	0.02	0.03	lasso	2	0.03	2.1e-10	-7.44	-7.7	1.3e-14	-0.10	1.00	0.00	FALSE
44	YFS	Blood	TSEN2	0.14	0.10	enet	34	0.14	2.7e-44	3.92	7.6	2.7e-14	0.07	1.00	0.00	FALSE
45	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	TSEN2	0.08	0.02	blup	78	0.05	2.3e-03	3.99	7.2	8.9e-13	0.17	0.04	0.05	FALSE
46	The Cancer Genome Atlas	Colon Adenocarcinoma	MKRN2	0.10	0.07	lasso	1	0.06	1.9e-04	-6.87	-6.9	6.2e-12	-0.15	0.05	0.31	FALSE
47	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MKRN2	0.07	0.04	lasso	2	0.03	3.4e-04	-6.87	-6.9	6.8e-12	-0.14	0.08	0.63	FALSE
48	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RAF1	0.03	0.02	blup	59	0.02	1.6e-03	-5.68	6.8	8.4e-12	0.33	0.21	0.28	FALSE
49	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MKRN2	0.14	0.09	lasso	4	0.14	1.9e-15	-6.87	-6.2	5.1e-10	-0.19	0.13	0.87	FALSE
50	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SYN2	0.06	0.09	lasso	1	0.09	4.8e-10	5.57	5.6	2.6e-08	0.10	1.00	0.00	FALSE
51	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	MKRN2	0.18	0.20	blup	48	0.19	7.5e-11	-2.13	-5.7	1.5e-08	-0.19	0.85	0.15	FALSE
52	The Cancer Genome Atlas	Brain Lower Grade Glioma	TIMP4	0.04	0.01	enet	4	0.03	2.2e-04	5.40	6.4	1.4e-10	0.15	0.12	0.08	FALSE
53	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MKRN2	0.18	0.03	enet	9	0.05	1.8e-03	-6.87	-6.0	1.7e-09	-0.17	0.02	0.60	FALSE
54	The Cancer Genome Atlas	Lung Adenocarcinoma	MKRN2	0.17	0.10	lasso	3	0.09	3.6e-10	-6.87	-6.9	6.3e-12	-0.19	0.96	0.04	FALSE
55	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TSEN2	0.06	0.00	enet	18	0.03	6.2e-03	-7.48	5.5	5.1e-08	0.18	0.03	0.05	FALSE
56	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CAND2	0.10	0.00	blup	65	0.01	1.8e-01	-0.97	-5.4	6.7e-08	-0.17	0.03	0.21	FALSE
57	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	MKRN2	0.20	0.13	lasso	3	0.12	8.8e-06	-6.87	-7.9	2.4e-15	-0.24	0.03	0.84	FALSE
58	The Cancer Genome Atlas	Prostate Adenocarcinoma	MKRN2	0.04	0.01	blup	51	0.02	5.3e-03	-6.87	-6.2	7.5e-10	-0.23	0.06	0.46	FALSE
59	The Cancer Genome Atlas	Prostate Adenocarcinoma	SYN2	0.11	0.12	lasso	6	0.11	1.0e-11	4.66	5.2	2.3e-07	0.15	1.00	0.00	FALSE
60	The Cancer Genome Atlas	Testicular Germ Cell Tumors	ATG7	0.42	0.08	lasso	4	0.05	6.0e-03	-6.49	-6.7	2.8e-11	0.00	0.00	0.82	TRUE
61	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RAF1	0.31	0.16	lasso	4	0.16	3.8e-06	7.01	7.0	1.9e-12	0.29	0.48	0.14	FALSE
62	The Cancer Genome Atlas	Thyroid Carcinoma	MKRN2	0.22	0.14	lasso	4	0.14	1.5e-13	-6.87	-8.0	1.5e-15	-0.18	0.96	0.04	FALSE
63	The Cancer Genome Atlas	Thyroid Carcinoma	RAF1	0.08	0.05	blup	59	0.07	9.6e-08	-8.03	5.9	4.8e-09	0.27	0.01	0.99	FALSE