[Hub]/) : Traits : Blood White Count :

chr6:33,662,667-36,121,375

Best TWAS P=7.95e-22 · Best GWAS P=2.9e-21 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Coronary ANKS1A 0.23 0.09 lasso 17 0.09 5.8e-04 -1.744 5.5 3.7e-08 -0.24 0.06 0.08 FALSE
2 GTEx Cells EBV-transformed lymphocytes C6orf106 0.20 0.00 lasso 5 0.00 2.7e-01 -6.071 -5.9 4.1e-09 0.15 0.07 0.06 FALSE
3 GTEx Cells Transformed fibroblasts NUDT3 0.11 0.03 lasso 3 0.02 9.2e-03 -6.099 5.9 4.7e-09 -0.19 0.08 0.69 FALSE
4 GTEx Muscle Skeletal C6orf106 0.08 0.06 lasso 4 0.06 7.1e-07 -5.396 6.2 4.7e-10 -0.14 0.98 0.00 FALSE
5 GTEx Nerve Tibial DEF6 0.15 0.00 lasso 8 0.00 1.6e-01 -9.427 5.8 5.8e-09 -0.81 0.02 0.87 FALSE
6 GTEx Pancreas C6orf106 0.14 0.11 enet 11 0.13 2.8e-06 -5.517 -5.1 2.7e-07 0.03 0.86 0.01 TRUE
7 GTEx Testis ZNF76 0.15 0.14 enet 8 0.12 4.4e-06 -5.716 6.0 2.4e-09 -0.78 0.85 0.10 FALSE
8 GTEx Whole Blood DEF6 0.14 0.05 lasso 4 0.03 9.9e-04 -9.384 6.6 3.4e-11 -0.84 0.02 0.98 FALSE
9 METSIM Adipose ZNF76 0.11 0.07 blup 405 0.06 6.3e-10 -9.075 9.6 8.0e-22 -0.81 0.08 0.92 TRUE
10 NTR Blood DEF6 0.03 0.02 bslmm 420 0.02 7.2e-07 -9.441 8.6 8.8e-18 -0.84 0.02 0.98 FALSE
11 NTR Blood ZNF76 0.01 0.00 blup 424 0.00 3.8e-02 -9.210 8.0 9.6e-16 -0.81 0.05 0.79 FALSE
12 ROSMAP Brain Pre-frontal Cortex DEF6 0.04 0.02 bslmm 421 0.02 1.8e-03 -5.677 7.0 2.4e-12 -0.88 0.03 0.96 FALSE
13 ROSMAP Brain Pre-frontal Cortex ZNF76 0.04 0.00 blup 424 0.02 2.1e-03 -9.459 8.9 5.6e-19 -0.82 0.02 0.96 TRUE
14 ROSMAP Brain Pre-frontal Cortex PACSIN1 0.09 0.00 blup 359 0.02 4.5e-04 -5.002 -5.8 8.6e-09 0.07 0.10 0.51 FALSE
15 ROSMAP Brain Pre-frontal Cortex RPS10 0.11 0.01 blup 356 0.04 5.0e-06 -6.713 -5.6 1.7e-08 0.33 0.00 0.99 TRUE
16 ROSMAP Brain Pre-frontal Cortex RPL10A 0.30 0.18 bslmm 409 0.19 2.6e-24 -3.840 -5.2 1.7e-07 0.31 1.00 0.00 FALSE
17 YFS Blood ANKS1A 0.04 0.00 bslmm 451 0.02 6.8e-07 0.025 -6.7 1.9e-11 0.38 0.74 0.11 FALSE
18 YFS Blood RPS10 0.05 0.05 bslmm 353 0.05 2.2e-16 -6.713 -6.5 9.6e-11 0.28 0.01 0.99 FALSE
19 YFS Blood ZNF76 0.05 0.08 lasso 4 0.07 6.7e-23 -9.433 9.4 3.4e-21 -1.00 0.02 0.98 TRUE
20 The Cancer Genome Atlas Breast Invasive Carcinoma RPL10A 0.03 0.00 blup 55 0.01 1.4e-03 -3.791 -6.1 9.1e-10 0.51 0.03 0.42 FALSE
21 The Cancer Genome Atlas Breast Invasive Carcinoma RPS10 0.01 0.01 enet 1 0.01 1.2e-02 -6.713 -6.7 1.9e-11 0.26 0.00 0.99 TRUE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C6orf106 0.04 0.01 blup 68 0.01 2.4e-02 -5.479 -5.8 6.7e-09 0.12 0.01 0.68 FALSE
23 The Cancer Genome Atlas Brain Lower Grade Glioma C6orf106 0.04 0.05 lasso 4 0.03 8.1e-05 -5.543 -5.2 2.3e-07 0.11 0.01 0.99 TRUE
24 The Cancer Genome Atlas Brain Lower Grade Glioma DEF6 0.04 0.01 blup 50 0.03 6.2e-04 -9.410 8.2 3.1e-16 -0.88 0.01 0.95 FALSE
25 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ZNF76 0.08 0.05 lasso 10 0.07 4.9e-04 -8.023 -8.6 9.5e-18 0.85 0.04 0.51 TRUE
26 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma FKBP5 0.19 0.01 blup 84 0.05 4.0e-03 -0.641 5.1 3.0e-07 0.02 0.01 0.09 TRUE
27 The Cancer Genome Atlas Prostate Adenocarcinoma RPL10A 0.09 0.03 enet 19 0.07 1.1e-07 -3.791 -5.2 2.2e-07 0.38 0.83 0.12 FALSE
28 The Cancer Genome Atlas Prostate Adenocarcinoma ZNF76 0.03 0.02 lasso 3 0.02 3.5e-03 -5.204 7.7 1.0e-14 -0.86 0.04 0.86 FALSE
29 The Cancer Genome Atlas Testicular Germ Cell Tumors PPARD 0.12 0.10 lasso 5 0.05 5.3e-03 -5.765 6.5 6.7e-11 -0.52 0.34 0.08 FALSE
30 The Cancer Genome Atlas Thyroid Carcinoma SCUBE3 0.03 0.01 blup 62 0.03 8.9e-04 -8.017 9.4 5.6e-21 -0.92 0.03 0.79 FALSE