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chr19:15,771,809-20,387,532

Best TWAS P=7.76e-46 · Best GWAS P=1.06e-61 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Artery Tibial	EPS15L1	0.09	0.01	lasso	8	0.04	4.4e-04	15.56	14.2	1.4e-45	0.64	0.08	0.16	TRUE
29	GTEx	Ovary	C19orf44	0.26	0.17	lasso	3	0.21	8.8e-06	10.48	-14.0	2.0e-44	-0.63	0.24	0.13	TRUE
37	ROSMAP	Brain Pre-frontal Cortex	C19orf44	0.18	0.14	enet	18	0.15	1.1e-18	10.97	-13.5	2.2e-41	-0.65	1.00	0.00	TRUE
35	METSIM	Adipose	SLC35E1	0.12	0.02	enet	38	0.06	1.9e-09	15.54	11.6	3.4e-31	0.47	0.69	0.01	TRUE
40	YFS	Blood	SLC35E1	0.04	0.02	bslmm	349	0.02	8.2e-08	9.39	11.3	8.2e-30	0.39	0.93	0.00	TRUE
64	The Cancer Genome Atlas	Thyroid Carcinoma	CHERP	0.03	0.00	blup	51	0.01	2.8e-02	10.19	10.8	3.5e-27	0.31	0.02	0.34	TRUE
39	YFS	Blood	LRRC25	0.35	0.19	enet	24	0.32	9.5e-108	6.52	-7.6	3.6e-14	-0.04	0.00	1.00	TRUE
15	GTEx	Cells Transformed fibroblasts	HAUS8	0.12	0.05	enet	19	0.05	1.0e-04	4.11	-5.7	1.3e-08	-0.04	0.75	0.01	TRUE
26	GTEx	Muscle Skeletal	CTC-429P9.1	0.09	0.00	enet	18	0.02	3.8e-03	-0.46	5.3	1.4e-07	0.25	0.19	0.04	TRUE
14	GTEx	Cells Transformed fibroblasts	MAP1S	0.24	0.18	enet	24	0.14	4.9e-11	-4.40	-5.2	1.5e-07	0.00	0.24	0.74	TRUE
38	ROSMAP	Brain Pre-frontal Cortex	ATP13A1	0.10	0.07	lasso	5	0.06	1.3e-08	5.45	-5.2	1.8e-07	0.00	0.00	1.00	TRUE
54	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C19orf44	0.10	0.05	blup	44	0.07	1.7e-05	15.56	-14.2	7.8e-46	-0.63	0.02	0.92	FALSE
33	METSIM	Adipose	EPS15L1	0.04	0.02	lasso	4	0.02	2.8e-04	15.54	14.0	1.3e-44	0.60	0.43	0.02	FALSE
56	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C19orf44	0.09	0.03	enet	5	0.03	1.5e-02	15.54	-13.4	9.5e-41	-0.60	0.02	0.33	FALSE
20	GTEx	Esophagus Muscularis	EPS15L1	0.10	0.02	enet	18	0.04	1.6e-03	9.78	13.3	2.8e-40	0.43	0.20	0.34	FALSE
1	CommonMind	Brain Pre-frontal Cortex	C19orf44	0.12	0.09	bslmm	400	0.13	2.1e-15	11.10	-13.0	2.1e-38	-0.58	0.99	0.01	FALSE
60	The Cancer Genome Atlas	Skin Cutaneous Melanoma	C19orf44	0.12	0.01	blup	45	0.09	2.3e-03	10.19	-12.6	1.4e-36	-0.49	0.01	0.46	FALSE
61	The Cancer Genome Atlas	Stomach Adenocarcinoma	C19orf44	0.07	0.02	lasso	2	0.01	2.7e-02	9.92	-11.8	6.6e-32	-0.48	0.11	0.10	FALSE
32	METSIM	Adipose	C19orf44	0.12	0.15	enet	18	0.15	5.0e-22	11.10	-11.6	4.6e-31	-0.56	1.00	0.00	FALSE
58	The Cancer Genome Atlas	Prostate Adenocarcinoma	C19orf44	0.23	0.27	lasso	4	0.27	3.1e-28	11.10	-11.5	2.2e-30	-0.56	1.00	0.00	FALSE
27	GTEx	Nerve Tibial	C19orf44	0.28	0.24	enet	11	0.25	4.5e-18	10.48	-11.3	2.3e-29	-0.54	1.00	0.00	FALSE
50	The Cancer Genome Atlas	Brain Lower Grade Glioma	C19orf44	0.10	0.09	lasso	2	0.09	6.3e-10	11.10	-11.2	3.7e-29	-0.55	1.00	0.00	FALSE
47	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C19orf44	0.07	0.06	lasso	3	0.06	1.7e-07	11.10	-11.2	4.7e-29	-0.55	0.92	0.02	FALSE
8	GTEx	Brain Frontal Cortex BA9	C19orf44	0.27	0.22	lasso	1	0.19	1.0e-05	11.10	-11.1	1.3e-28	-0.55	0.22	0.16	FALSE
10	GTEx	Breast Mammary Tissue (Male)	C19orf44	0.12	0.02	lasso	1	0.01	2.2e-01	11.10	-11.1	1.3e-28	-0.55	0.03	0.27	FALSE
31	GTEx	Thyroid	C19orf44	0.16	0.13	lasso	1	0.13	5.1e-10	11.10	-11.1	1.3e-28	-0.55	1.00	0.00	FALSE
42	The Cancer Genome Atlas	Breast Invasive Carcinoma	C19orf44	0.05	0.06	lasso	1	0.06	1.1e-12	11.10	-11.1	1.3e-28	-0.55	1.00	0.00	FALSE
11	GTEx	Breast Mammary Tissue (Female)	C19orf44	0.21	0.02	lasso	2	0.06	6.7e-03	11.10	-11.1	2.1e-28	-0.55	0.12	0.08	FALSE
23	GTEx	Muscle Skeletal	C19orf44	0.12	0.13	lasso	2	0.12	4.0e-12	11.10	-11.1	2.1e-28	-0.55	1.00	0.00	FALSE
63	The Cancer Genome Atlas	Thyroid Carcinoma	C19orf44	0.18	0.19	lasso	2	0.18	2.2e-17	11.10	-10.9	8.8e-28	-0.54	1.00	0.00	FALSE
53	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C19orf44	0.10	0.07	lasso	3	0.06	8.2e-08	10.97	-10.9	1.2e-27	-0.55	0.98	0.02	FALSE
3	GTEx	Adipose Visceral Omentum	C19orf44	0.17	0.17	enet	4	0.17	5.6e-09	11.10	-10.7	9.6e-27	-0.54	1.00	0.00	FALSE
5	GTEx	Artery Tibial	C19orf44	0.27	0.25	lasso	3	0.26	5.6e-20	10.48	-10.6	2.2e-26	-0.53	1.00	0.00	FALSE
4	GTEx	Artery Aorta	C19orf44	0.33	0.35	lasso	1	0.35	6.0e-20	10.48	-10.5	1.1e-25	-0.53	1.00	0.00	FALSE
17	GTEx	Esophagus Gastroesophageal Junction	C19orf44	0.27	0.30	lasso	1	0.27	3.9e-10	10.48	-10.5	1.1e-25	-0.53	0.98	0.01	FALSE
41	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C19orf44	0.05	0.02	enet	3	0.01	8.4e-02	10.97	-10.4	1.8e-25	-0.53	0.14	0.19	FALSE
13	GTEx	Cells Transformed fibroblasts	C19orf44	0.29	0.27	lasso	5	0.26	6.8e-20	10.48	-10.3	5.6e-25	-0.53	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	C19orf44	0.19	0.17	lasso	2	0.16	1.0e-12	10.48	-10.2	2.5e-24	-0.53	1.00	0.00	FALSE
16	GTEx	Colon Transverse	C19orf44	0.13	0.10	enet	15	0.08	1.7e-04	11.10	-10.1	6.7e-24	-0.48	0.30	0.08	FALSE
30	GTEx	Skin Sun Exposed Lower leg	C19orf44	0.15	0.11	enet	8	0.11	1.5e-09	11.10	-9.9	2.6e-23	-0.52	1.00	0.00	FALSE
49	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C19orf44	0.13	0.05	blup	44	0.07	5.3e-05	10.97	-9.8	1.8e-22	-0.52	0.60	0.09	FALSE
45	The Cancer Genome Atlas	Colon Adenocarcinoma	C19orf44	0.16	0.12	enet	6	0.12	3.2e-07	10.97	-9.7	4.2e-22	-0.49	0.98	0.00	FALSE
9	GTEx	Breast Mammary Tissue	C19orf44	0.17	0.20	enet	6	0.21	2.8e-11	10.97	-9.6	5.9e-22	-0.50	1.00	0.00	FALSE
22	GTEx	Heart Left Ventricle	C19orf44	0.14	0.04	enet	11	0.04	2.6e-03	10.97	-9.2	2.5e-20	-0.45	0.12	0.22	FALSE
19	GTEx	Esophagus Muscularis	C19orf44	0.34	0.22	enet	12	0.23	4.6e-14	10.48	-9.1	1.1e-19	-0.44	1.00	0.00	FALSE
21	GTEx	Heart Atrial Appendage	C19orf44	0.21	0.14	lasso	5	0.13	1.7e-06	11.10	-9.1	1.4e-19	-0.45	0.62	0.04	FALSE
48	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C19orf44	0.22	0.19	blup	44	0.20	9.4e-22	10.97	-8.8	1.4e-18	-0.48	1.00	0.00	FALSE
18	GTEx	Esophagus Mucosa	C19orf44	0.12	0.09	enet	2	0.09	7.1e-07	4.88	-7.4	1.1e-13	-0.44	0.84	0.13	FALSE
24	GTEx	Muscle Skeletal	SMIM7	0.09	0.00	enet	25	0.03	2.5e-04	-0.31	6.5	9.4e-11	0.35	0.14	0.07	FALSE
51	The Cancer Genome Atlas	Brain Lower Grade Glioma	SSBP4	0.03	0.03	lasso	1	0.03	9.7e-05	6.37	-6.4	1.9e-10	-0.08	0.00	1.00	FALSE
65	The Cancer Genome Atlas	Thyroid Carcinoma	LRRC25	0.05	0.08	lasso	3	0.07	5.4e-07	6.52	-6.3	3.1e-10	-0.07	0.00	1.00	FALSE
55	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SSBP4	0.06	0.02	blup	37	0.05	4.3e-04	4.32	-6.1	1.0e-09	-0.05	0.11	0.22	FALSE
28	GTEx	Nerve Tibial	CTC-429P9.3	0.13	0.02	enet	15	0.03	3.6e-03	8.90	-5.9	2.8e-09	-0.32	0.08	0.18	FALSE
36	NTR	Blood	LRRC25	0.03	0.01	lasso	4	0.01	2.9e-04	6.52	-5.9	3.7e-09	-0.07	0.00	0.99	FALSE
25	GTEx	Muscle Skeletal	CTC-429P9.5	0.09	0.01	enet	22	0.01	4.7e-02	-0.31	5.7	1.1e-08	0.19	0.08	0.12	FALSE
62	The Cancer Genome Atlas	Stomach Adenocarcinoma	PGPEP1	0.04	0.01	blup	56	0.03	3.1e-03	-1.55	5.6	1.7e-08	0.02	0.06	0.06	FALSE
12	GTEx	Breast Mammary Tissue (Female)	CTC-429P9.1	0.24	0.00	enet	32	0.02	8.9e-02	4.94	5.6	2.7e-08	0.34	0.04	0.25	FALSE
52	The Cancer Genome Atlas	Lung Adenocarcinoma	PGPEP1	0.03	0.01	blup	55	0.02	1.1e-03	4.50	5.6	2.7e-08	0.03	0.05	0.03	FALSE
46	The Cancer Genome Atlas	Colon Adenocarcinoma	LRRC25	0.06	0.05	blup	44	0.04	1.5e-03	4.26	-5.5	4.2e-08	-0.06	0.11	0.25	FALSE
7	GTEx	Artery Tibial	CTD-2538G9.5	0.09	0.00	enet	12	0.00	4.9e-01	9.44	5.5	4.5e-08	0.31	0.10	0.03	FALSE
59	The Cancer Genome Atlas	Prostate Adenocarcinoma	HAUS8	0.13	0.10	blup	55	0.11	7.8e-12	4.11	-5.3	9.2e-08	-0.03	0.25	0.62	FALSE
57	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C19orf44	0.23	0.06	enet	19	0.08	3.7e-04	4.88	-5.3	1.2e-07	-0.37	0.06	0.16	FALSE
44	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	LRRC25	0.14	0.07	enet	5	0.10	8.3e-06	6.52	-5.3	1.4e-07	-0.05	0.00	0.99	FALSE
34	METSIM	Adipose	FCHO1	0.05	0.03	lasso	3	0.04	2.1e-06	4.17	-5.2	2.5e-07	0.01	0.35	0.61	FALSE
43	The Cancer Genome Atlas	Breast Invasive Carcinoma	LRRC25	0.06	0.07	enet	13	0.06	5.9e-13	6.37	-5.1	3.1e-07	-0.03	0.00	1.00	FALSE