TWAS hub - SLC35E1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.1153	0.0332	5.5e-06	0.020	0.053	0.061	0.060	0.032	4.2e-04	1.8e-08	1.9e-09	2.6e-09	1.3e-05
2	YFS	Blood	0.0376	0.0123	1.0e-05	0.016	0.020	0.011	0.022	0.011	4.6e-06	3.5e-07	1.4e-04	8.2e-08	9.8e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood White Count	17.7	131.1	134.6	11.6	11.3
Asthma	7.4	14.7	17.6	-4.2	-3.4
Asthma (self-reported)	7.0	14.0	17.3	-4.2	-3.3
Allergy	5.4	12.4	15.8	4.0	3.0
Maternal smoking around birth	4.9	7.0	9.5	-3.1	-2.1
Tinnitus: Yes, but not now, but have in the past	4.5	4.8	9.0	-3.0	-0.7
Loneliness, isolation	4.1	5.7	7.5	-2.7	-2.0
Rheumatoid Arthritis	3.4	4.7	7.8	-1.3	-2.8
Past tobacco smoking	3.4	6.3	12.0	3.5	0.8
Heel bone mineral density (BMD) T-score, automated (left)	3.3	7.4	14.4	-3.8	-0.6
Allergy or Eczema	3.2	8.3	13.6	-3.7	-1.7
Frequency of depressed mood in last 2 weeks	3.2	4.5	4.8	-2.1	-2.2
Wheeze or whistling in the chest in last year	3.2	5.8	8.9	-3.0	-1.6
Medication: Amlodipine	3.1	4.3	8.0	-0.8	-2.8
Illnesses of father: None of the above (group 1)	3.1	3.8	4.4	1.8	2.1
Ever had prostate specific antigen (PSA) test	3.1	3.6	4.3	2.1	1.7
Respiratory disease	3.0	6.6	10.2	-3.2	-1.7
Smoking status: Previous	3.0	4.5	8.0	-2.8	-1.0
Father’s age at death	2.8	3.8	6.6	2.6	1.0
Diabetes (father)	2.7	3.4	5.4	1.2	2.3
Pulse wave Arterial Stiffness index	2.7	3.1	3.4	-1.8	-1.7
Pulse rate, automated reading	2.7	8.9	8.9	-3.0	-3.0
Depression (Nagel 2018)	2.6	3.9	5.1	-2.3	-1.6
Serious illness, injury or assault of a close relative in last 2 years	2.6	3.0	4.6	2.1	1.2
Pain type(s) experienced in last month: Hip pain	2.6	3.3	3.8	-1.7	-2.0
Fractured/broken bones in last 5 years	2.6	3.4	3.5	1.9	1.8
Fed-up feelings	2.5	4.6	4.7	-2.1	-2.2
Medication: Lansoprazole	2.5	2.8	4.0	-2.0	-1.3
Pulse wave peak to peak time	2.5	3.0	3.1	1.7	1.8
Tinnitus: Yes, now most or all of the time	2.5	3.0	5.1	2.3	0.9
Depressed Affect (Nagel 2018)	2.3	4.9	6.9	-2.6	-1.7
Cardiovascular Disease	2.3	7.7	10.9	-2.1	-3.3
Hayfever, allergic rhinitis or eczema	2.3	5.0	5.2	-2.3	-2.2
Mouth/teeth dental problems: Dentures	2.3	3.9	4.5	-1.8	-2.1
Pulse wave reflection index	2.3	2.8	3.5	-1.9	-1.5
Taking other prescription medications	2.2	3.4	4.4	-2.1	-1.5
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.5	5.4	-1.2	-2.3
Major Depression (MDD)	2.0	2.4	4.7	-2.2	-0.2
Eye problems/disorders: Glaucoma	2.0	2.4	4.8	-2.2	-0.1
Friendships satisfaction	1.9	2.3	3.9	0.8	2.0
Bipolar Disorder (2011)	1.8	1.8	3.6	0.0	1.9
Supplements: Zinc	1.8	1.9	2.6	-1.6	-1.1
Hayfever/allergic rhinitis (self-reported)	1.8	2.4	3.0	-1.7	-1.3
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	3.4	1.8	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	1.7	3.8	7.5	-2.7	-0.4
Medication: Aspirin	1.7	2.3	3.0	-1.2	-1.7
Osteoporosis (self-reported)	1.7	2.1	3.8	1.9	0.6
Ever smoked	1.7	3.0	5.9	-2.4	-0.1
Heel T-Score	1.6	12.8	23.5	-4.8	-1.5
Average weekly spirits intake	1.6	1.9	1.9	-1.4	-1.4
Diabetes (mother)	1.6	2.0	2.5	-1.6	-1.3
Leg fat percentage (right)	1.6	5.7	6.8	-2.6	-2.1
Eye problems/disorders: Cataract	1.6	1.8	3.6	-0.1	1.9
Medication: Aspirin	1.6	2.0	2.7	-1.2	-1.6
Illnesses of father: High blood pressure	1.6	1.9	2.1	-1.3	-1.4
Vitamin and mineral supplements	1.5	2.1	3.1	-1.8	-1.0
Heart attack/myocardial infarction (self-reported)	1.5	1.9	3.5	0.5	-1.9
HbA1C	1.4	1.5	2.9	-0.4	-1.7
LDL Cholesterol	1.4	2.2	2.2	-1.5	-1.5
Smoking Status	1.4	3.3	6.5	-2.6	-0.4
Neuroticism	1.4	3.4	3.7	-1.7	-1.9
Chronic bronchitis/emphysema (father)	1.4	1.6	3.1	-0.4	-1.8
Heart attack	1.4	1.8	3.6	0.2	-1.9
Diabetes (self-reported)	1.4	2.2	2.6	-1.3	-1.6
Body fat percentage	1.4	5.6	6.1	-2.5	-2.3
Number of full sisters	1.4	1.7	1.9	-1.4	1.2
Mood swings	1.4	2.5	3.0	-1.7	-1.4
Miserableness	1.4	2.4	4.2	-2.0	-0.8
Blood Eosinophil Count	1.3	9.7	15.8	-1.9	-4.0
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	1.5	-1.2	-1.1
Number of live births	1.3	1.9	3.6	1.9	0.4
Heart disease (mother)	1.3	1.5	2.2	-0.9	-1.5
Average weekly red wine intake	1.3	1.9	3.3	1.8	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	3.1	1.8	1.5
Ulcerative Colitis (UC)	1.2	2.3	4.0	2.0	0.8
Lupus	1.2	1.9	2.3	1.5	1.2
Trunk fat percentage	1.2	4.9	5.3	-2.3	-2.1
Alcohol usually taken with meals	1.2	2.0	3.9	2.0	0.4
Arm fat percentage (right)	1.2	4.8	4.9	-2.2	-2.2
Length of working week for main job	1.2	1.3	2.6	-0.3	1.6
Medication: Ventolin 100micrograms inhaler	1.2	1.5	2.0	-1.4	-1.0
Average weekly champagne plus white wine intake	1.2	1.7	2.1	1.4	1.1
Neuroticism (Nagel 2018)	1.1	2.6	4.1	-1.1	-2.0
Coronary Artery Disease (CAD)	1.1	1.3	2.5	0.2	-1.6
Crohns Disease (2012)	1.1	1.8	3.5	-1.9	-0.2
Neuroticism (2016)	1.1	1.6	2.8	-1.7	0.6
Relative age voice broke	1.1	1.6	2.9	-0.6	1.7
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	1.7	-1.3	-1.3
Pain all over the body in last month	1.1	1.2	1.5	-1.2	-1.0
Neuroticism score	1.1	2.4	2.5	-1.6	-1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	1.7	-1.0	-1.3
Health satisfaction	1.1	1.4	2.7	-0.4	-1.6
Mouth/teeth dental problems: Loose teeth	1.1	1.3	1.5	-1.1	-1.2
Commuting to job workplace: Walk	1.1	1.2	2.3	1.5	0.4
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	2.8	0.9	1.7
Back pain experienced in last month	1.1	1.6	2.6	-0.8	-1.6
Supplements: Fish oil (including cod liver oil)	1.1	1.4	1.7	1.1	1.3
Leg fat percentage (left)	1.1	4.0	5.4	-2.3	-1.6
Lung FEV1/FVC ratio	1.0	5.2	8.5	1.4	2.9
Chronotype (morning person)	1.0	2.3	2.9	1.7	1.3
High blood pressure	1.0	2.9	3.6	-1.5	-1.9
Medication: Levothyroxine sodium	1.0	1.6	3.3	1.8	0.0
Waist circumference	1.0	3.7	4.9	-2.2	-1.6
Had menopause	1.0	1.2	1.9	-0.7	-1.4
Pulse rate	1.0	1.7	2.8	-1.7	-0.8
Number of children fathered	1.0	1.1	1.7	-0.8	1.3
Illnesses of father: Heart disease	1.0	1.4	2.6	-1.6	-0.6
Arm fat percentage (left)	1.0	4.1	4.7	-2.2	-1.9
Ever had bowel cancer screening	1.0	1.2	1.7	0.9	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	2.2	-1.5	-0.3
Mineral and other dietary supplements	1.0	1.3	1.7	-0.9	-1.3
Mother’s age at death	1.0	1.2	2.4	0.1	-1.6
Medication: Bendroflumethiazide	1.0	1.5	2.5	-0.7	-1.6
Irritability	1.0	1.7	2.7	-0.9	-1.6
Risk taking	1.0	1.5	2.8	1.7	0.4
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	2.5	-1.6	0.2
Pain experienced in last month	1.0	1.7	1.7	1.3	1.3
Hypothyroidism (self reported)	0.9	2.0	2.1	1.5	-1.4
Lung FVC	0.9	4.3	6.6	2.6	1.5
Hand grip strength (left)	0.9	2.3	2.5	-1.6	-1.5
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	1.3	1.1	1.0
Medication for hormone replacement therapy	0.9	1.0	1.4	1.2	0.7
Pack years adult smoking proportion	0.9	1.4	1.8	-1.4	-1.0
Trunk fat mass	0.9	3.7	4.7	-2.2	-1.7
Financial difficulties in last 2 years	0.9	1.3	1.6	1.0	1.3
Prospective memory result	0.9	1.1	2.0	0.3	1.4
Illnesses of mother	0.9	1.1	1.5	0.8	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	2.6	-1.6	-0.0
Glaucoma (self-reported)	0.9	1.1	2.1	-1.5	-0.0
Eye problems/disorders: None of the above	0.9	1.1	2.1	1.5	-0.2
Medication: Ibuprofen	0.9	1.1	1.1	1.0	1.0
Leg fat mass (right)	0.9	3.5	5.2	-2.3	-1.3
Chest pain or discomfort	0.9	1.2	2.2	-1.5	-0.6
Cholesterol lowering medication	0.9	1.4	1.7	-1.0	-1.3
Heart disease (siblings)	0.9	1.1	1.7	1.3	0.8
Fasting Glucose	0.8	0.9	1.5	-0.6	-1.2
Primary Biliary Cirrhosis	0.8	1.2	2.1	1.5	-0.5
Blood Platelet Count	0.8	9.0	17.5	4.2	0.7
Waist Hip Ratio (WHR)	0.8	3.6	5.1	-1.5	-2.3
Impedance of leg (right)	0.8	4.1	5.5	-1.6	-2.3
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	1.3	0.7	1.1
Impedance of arm (right)	0.8	3.8	6.9	-0.9	-2.6
Worrier / anxious feelings	0.8	1.5	2.1	-0.9	-1.4
Medication: Blood pressure	0.8	1.4	1.5	-1.1	-1.2
Medication: Allopurinol	0.8	1.1	2.2	-1.5	-0.3
Medication: Seretide 50 evohaler	0.8	0.9	1.0	-1.0	-0.9
Whole body fat mass	0.8	3.4	4.5	-2.1	-1.5
Leg pain on walking	0.8	1.0	1.7	-0.5	-1.3
Hypertension (Self-reported)	0.8	2.3	2.8	-1.3	-1.7
Medication: Blood pressure	0.8	1.4	2.0	-1.4	-1.0
Supplements: Calcium	0.8	0.9	1.6	1.3	0.4
Pack years of smoking	0.8	1.1	1.2	-1.0	-1.1
Alzheimer’s Disease (including proxy)	0.7	1.1	1.2	-1.1	1.0
Number of treatments/medications taken	0.7	1.3	2.7	-1.6	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	1.5	-1.2	-0.7
Medication: Atenolol	0.7	0.9	1.7	-1.3	0.2
Medication: Ramipril	0.7	0.9	1.7	-0.2	-1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	2.9	1.7	1.3
Arm fat mass (right)	0.7	2.7	3.4	-1.9	-1.4
Birth weight of first child	0.7	1.2	1.3	1.1	-1.1
Birth weight	0.7	1.5	1.8	1.1	1.4
Number of full brothers	0.7	0.8	1.7	-1.3	-0.0
Emphysema/chronic bronchitis	0.7	0.8	0.8	-0.9	-0.8
Overall health rating	0.7	1.6	2.0	-1.4	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	1.3	-0.6	-1.1
Arm fat mass (left)	0.7	2.9	3.6	-1.9	-1.5
Average weekly beer plus cider intake	0.7	1.0	1.9	-1.4	-0.3
Vascular/heart problems diagnosed by doctor	0.7	1.9	2.2	1.3	1.5
Basal cell carcinoma (self-reported)	0.7	0.8	1.0	0.8	1.0
Impedance of whole body	0.7	3.4	6.0	-0.9	-2.5
Leg fat mass (left)	0.7	2.9	4.5	-2.1	-1.1
Prostate Cancer	0.6	0.8	1.3	1.2	-0.5
HDL Cholesterol	0.6	1.0	1.5	0.7	1.2
Ulcerative Colitis	0.6	0.8	1.0	0.8	1.0
Blood Red Count	0.6	5.4	7.6	-1.8	-2.8
Type 2 Diabetes (T2D) (2018)	0.6	1.2	1.9	-0.7	-1.4
Multivitamins +/- minerals	0.6	0.8	1.2	0.7	1.1
Impedance of leg (left)	0.6	2.7	3.9	-1.2	-2.0
Number of incorrect matches in round	0.6	1.0	2.0	1.4	0.3
Mouth/teeth dental problems	0.6	0.9	1.3	1.1	0.8
Impedance of arm (left)	0.6	2.8	5.3	-0.5	-2.3
Ever taken oral contraceptive pill	0.6	0.7	1.4	-1.2	-0.0
Schizophrenia vs Biploar Disorder	0.5	0.6	1.1	-0.4	-1.1
Alzheimer’s Disease (in father)	0.5	0.5	0.8	-0.9	0.5
Crohns Disease (2017)	0.5	1.2	2.1	-1.4	0.5
Medication: Co-codamol	0.5	0.6	1.0	-0.5	-1.0
Severe depression (siblings)	0.5	0.6	0.9	1.0	0.5
Hand grip strength (right)	0.5	1.4	2.0	-1.4	-0.8
Age when periods started (menarche)	0.5	1.2	1.4	1.2	1.0
Had other major operations	0.5	0.7	0.8	-0.7	-0.9
Time employed in main current job	0.5	0.5	1.1	1.0	0.1
Medication for pain relief, constipation, heartburn	0.5	0.9	1.2	1.1	0.8
Neck or shoulder pain in last month	0.5	0.6	1.0	-1.0	-0.6
Angina (self-reported)	0.5	0.6	1.2	-0.3	-1.1
Medication: Omeprazole	0.5	0.7	1.1	-1.1	0.4
Diabetes diagnosed by doctor	0.5	0.8	1.4	-0.5	-1.2
Number of self-reported non-cancer illnesses	0.5	0.8	1.5	-1.2	-0.4
Commuting to job workplace: Public transport	0.5	0.6	0.7	0.9	0.7
Medication: Paracetamol	0.5	0.7	1.0	-1.0	0.7
Medication: Lisinopril	0.5	0.7	1.3	-0.2	1.1
Diastolic blood pressure, automated reading	0.5	1.4	1.9	-1.0	-1.4
Worry (Nagel 2018)	0.4	0.9	1.8	0.0	-1.3
Breast Cancer	0.4	1.1	1.2	1.1	1.0
Current tobacco smoking	0.4	0.6	1.2	-1.1	-0.3
Body mass index (BMI)	0.4	1.6	2.6	-1.6	-0.8
Nervous feelings	0.4	0.8	1.2	0.6	-1.1
Weight	0.4	1.9	3.1	-1.8	-0.8
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	1.3	1.1	1.1
Qualifications: A levels/AS levels or equivalent	0.4	1.0	1.6	0.5	-1.3
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	1.1	0.5	-1.1
High blood pressure (siblings)	0.4	0.6	0.9	-1.0	0.6
Forced vital capacity (FVC), Best measure	0.4	1.4	2.7	1.6	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	0.7	-0.8	0.6
Mean time to correctly identify matches	0.4	0.8	1.5	1.2	-0.4
Alcohol intake frequency.	0.4	0.8	1.6	0.1	-1.3
Comparative height size at age 10	0.4	2.5	2.9	1.7	1.4
Had major operations	0.4	0.5	0.9	0.9	-0.2
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.6	-0.8	-0.5
Handedness (chirality/laterality): Left-handed	0.4	0.4	0.8	-0.2	-0.9
Smoking status: Current	0.4	0.6	1.1	-1.1	-0.1
Hearing aid user	0.4	0.5	0.7	-0.4	-0.9
Ever depressed for a whole week	0.4	0.5	0.8	0.5	0.9
Bipolar Disorder (2018)	0.3	0.4	0.9	0.1	0.9
Age at First Birth	0.3	0.4	0.5	0.7	0.6
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.4	-0.4	-0.6
Relative age of first facial hair	0.3	0.5	0.6	-0.8	0.7
Angina	0.3	0.4	0.8	-0.2	-0.9
Medication: Metformin	0.3	0.5	0.9	-0.1	1.0
Townsend deprivation index at recruitment	0.3	0.5	0.6	-0.8	-0.6
High blood pressure (mother)	0.3	0.4	0.4	-0.7	-0.6
Hearing difficulty/problems with background noise	0.3	0.4	0.7	-0.4	0.8
Qualifications: None of the above	0.3	0.7	1.3	-1.1	-0.0
Hip circumference	0.3	1.4	2.7	-1.6	-0.3
Medication: Paracetamol	0.3	0.5	0.8	-0.9	0.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	0.7	0.5	0.9
Qualifications: College or University degree	0.3	1.1	1.1	1.1	1.0
Age at last live birth	0.3	0.4	0.8	-0.0	-0.9
Breast cancer (self-reported)	0.3	0.3	0.6	0.8	-0.0
Osteoarthritis (self-reported)	0.3	0.4	0.5	-0.7	0.5
Guilty feelings	0.3	0.5	0.8	-0.9	-0.5
Number of operations (self-reported)	0.3	0.5	0.9	-1.0	0.1
Age started oral contraceptive pill	0.3	0.4	0.6	0.5	0.7
Unable to work because of sickness or disability	0.3	0.4	0.7	-0.9	0.4
Commuting to job workplace: Cycle	0.3	0.3	0.6	0.3	0.8
Schizophrenia (2018)	0.2	0.3	0.6	-0.8	-0.2
Irritable Bowel Disease (IBD)	0.2	0.4	0.7	0.4	0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.4	0.8	-0.9	-0.1
Ovarian Cancer	0.2	0.3	0.6	0.8	0.1
Body Mass Index (BMI) (2010)	0.2	0.3	0.6	0.8	-0.0
BMI	0.2	1.2	1.7	-0.8	-1.3
Sensitivity / hurt feelings	0.2	0.4	0.6	-0.4	-0.8
Average weekly fortified wine intake	0.2	0.2	0.5	0.1	-0.7
Qualifications: CSEs or equivalent	0.2	0.3	0.3	0.6	-0.5
Stomach or abdominal pain in last month	0.2	0.3	0.4	-0.6	-0.4
Supplements: Glucosamine	0.2	0.2	0.3	0.4	0.5
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.5	-0.7	-0.2
Falls in the last year	0.2	0.2	0.5	-0.7	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.5	0.3	0.7
Lung cancer (father)	0.2	0.3	0.5	-0.1	-0.7
Exposure to tobacco smoke at home	0.2	0.2	0.3	-0.4	-0.5
Breastfed as a baby	0.2	0.2	0.3	-0.6	-0.3
Tense / ‘highly strung’	0.2	0.4	0.6	-0.5	-0.7
Loud music exposure frequency	0.2	0.2	0.4	0.1	-0.6
Blood clot in the leg (DVT)	0.2	0.2	0.3	0.6	0.3
Gout (self-reported)	0.2	0.3	0.6	-0.8	-0.1
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.2	-0.5	-0.5
Arm fat-free mass (right)	0.2	0.9	1.7	0.2	1.3
Age at first live birth	0.2	0.4	0.5	0.5	0.7
Shortness of breath walking on level ground	0.2	0.2	0.3	0.5	0.5
Suffer from ‘nerves’	0.2	0.4	0.8	0.1	0.9
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.5	-0.3	-0.7
Supplements: Vitamin C	0.2	0.3	0.6	0.8	0.0
Medication for cholesterol	0.2	0.3	0.3	0.6	0.5
Alcohol drinker status: Never	0.2	0.2	0.3	0.5	-0.4
Alcohol drinker status: Previous	0.2	0.3	0.4	0.7	-0.3
Bipolar Disorder or Schizophrenia	0.1	0.3	0.5	-0.7	0.3
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	-0.4	0.3
Reaction Time	0.1	0.2	0.3	0.5	-0.5
Mean Putamen Volume	0.1	0.1	0.1	-0.3	0.3
Schizophrenia (2014)	0.1	0.2	0.4	-0.1	0.6
Height	0.1	1.3	2.4	-1.6	-0.3
Systolic Blood Pressure	0.1	0.5	0.8	-0.9	-0.5
Ever had hysterectomy (womb removed)	0.1	0.1	0.2	-0.4	-0.0
Systolic blood pressure, automated reading	0.1	0.3	0.5	-0.4	-0.7
Sitting height	0.1	0.5	0.6	-0.6	0.8
Hair/balding pattern: Pattern 2	0.1	0.1	0.3	-0.5	0.1
Forced vital capacity (FVC)	0.1	0.4	0.7	0.8	0.3
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.1	-0.4	-0.2
Medication: Simvastatin	0.1	0.2	0.3	-0.6	-0.2
Trunk fat-free mass	0.1	0.4	0.8	0.1	0.9
Alcohol intake versus 10 years previously	0.1	0.2	0.3	-0.5	-0.1
Happiness	0.1	0.1	0.3	0.5	0.0
Medication: Cholesterol lowering	0.1	0.1	0.2	-0.2	-0.5
Depression (self-reported)	0.1	0.1	0.3	0.1	0.5
Trunk predicted mass	0.1	0.5	1.0	0.2	1.0
Hair/balding pattern: Pattern 4	0.1	0.2	0.3	-0.6	-0.1
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.2	-0.1	-0.4
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.1	0.3	0.2
Headache pain in last month	0.1	0.2	0.3	0.5	0.2
Exposure to tobacco smoke outside home	0.1	0.1	0.2	0.3	0.4
Worry too long after embarrassment	0.1	0.2	0.5	-0.1	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.3	-0.6	0.1
Arm predicted mass (right)	0.1	0.6	1.1	0.1	1.0
Knee pain experienced in last month	0.1	0.2	0.3	0.2	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.4	-0.6	-0.1
Whole body fat-free mass	0.1	0.5	1.0	0.1	1.0
Leg fat-free mass (right)	0.1	0.5	0.9	0.2	1.0
Long-standing illness, disability or infirmity	0.1	0.2	0.3	-0.5	-0.2
Whole body water mass	0.1	0.5	1.0	0.1	1.0
Leg predicted mass (right)	0.1	0.5	0.9	0.2	0.9
Wears glasses or contact lenses	0.1	0.1	0.1	0.3	-0.3
Financial situation satisfaction	0.1	0.1	0.1	0.4	0.3
Medication: Atorvastatin	0.1	0.2	0.3	-0.2	-0.5
Arm fat-free mass (left)	0.1	0.3	0.5	-0.4	0.7
Myopia	0.1	0.2	0.3	0.6	-0.2
Arm predicted mass (left)	0.1	0.5	0.7	-0.5	0.9
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.2	-0.4	0.3
Triglycerides	0.0	0.0	0.0	-0.1	0.2
Hair Pigment	0.0	0.1	0.2	-0.1	-0.4
Tanning	0.0	0.2	0.2	0.5	0.3
Hearing difficulty/problems: Yes	0.0	0.0	0.0	-0.2	0.1
Ever used hormone-replacement therapy (HRT)	0.0	0.0	0.0	0.1	-0.1
Leg fat-free mass (left)	0.0	0.2	0.3	-0.2	0.6
Serious illness, injury or assault to yourself	0.0	0.0	0.1	0.3	0.1
Leg predicted mass (left)	0.0	0.2	0.3	-0.2	0.5
Fluid intelligence score	0.0	0.1	0.1	-0.4	-0.2
Illnesses of siblings	0.0	0.1	0.1	-0.2	-0.3
Hair/balding pattern: Pattern 3	0.0	0.0	0.1	-0.2	0.1
Noisy workplace	0.0	0.0	0.1	-0.2	0.1
Standing height	0.0	0.0	0.1	-0.3	0.0
Peak expiratory flow (PEF)	0.0	0.1	0.1	-0.3	0.1
Comparative body size at age 10	0.0	0.1	0.1	-0.4	-0.2
Migraine (self-reported)	0.0	0.1	0.1	0.0	-0.3
Family relationship satisfaction	0.0	0.0	0.0	0.0	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	0.2	-0.1
Illnesses of siblings: Diabetes	0.0	0.0	0.0	0.1	0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.0	-0.2	0.2
Qualifications: nursing, teaching	0.0	0.1	0.1	0.4	-0.2
Medication: Gliclazide	0.0	0.0	0.1	0.1	-0.2
High cholesterol (Self-reported)	0.0	0.0	0.0	-0.0	-0.0
Basal metabolic rate	0.0	0.2	0.3	-0.4	0.5
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.0	0.2	0.0

Hub : Genes

SLC35E1

Models

Trait associations