Hub : Genes

SMIM7

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Breast Mammary Tissue (Male) 0.255 0.1670 1.2e-01 -0.008 NA -0.011 NA 0.019 5.2e-01 NA 7.3e-01 NA 1.2e-01
2 GTEx Breast Mammary Tissue (Female) 0.157 0.0902 6.8e-02 0.003 NA -0.010 NA -0.002 2.6e-01 NA 9.3e-01 NA 3.8e-01
3 GTEx Cells Transformed fibroblasts 0.218 0.0520 3.2e-06 0.062 NA 0.062 NA 0.066 1.9e-05 NA 2.0e-05 NA 1.1e-05
4 GTEx Lung 0.122 0.0413 1.8e-03 0.102 NA 0.104 NA 0.098 3.3e-08 NA 2.6e-08 NA 6.3e-08
5 GTEx Muscle Skeletal 0.089 0.0347 4.0e-03 0.001 NA 0.034 NA 0.014 2.8e-01 NA 2.5e-04 NA 1.3e-02
6 GTEx Nerve Tibial 0.134 0.0446 2.0e-03 0.118 NA 0.093 NA 0.107 1.1e-08 NA 4.1e-07 NA 5.3e-08
7 METSIM Adipose 0.096 0.0289 4.6e-05 0.037 0.025 0.020 0.040 0.022 2.4e-06 1.1e-04 4.1e-04 1.1e-06 2.3e-04
8 ROSMAP Brain Pre-frontal Cortex 0.122 0.0296 5.8e-07 0.071 0.051 0.090 0.081 0.089 2.0e-09 3.1e-07 1.2e-11 1.4e-10 1.8e-11

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.5 0.8 1.8 -0.2 -0.2 -1.0 -1.3 -0.4 -1.1 1.0 1.0
Bipolar Disorder or Schizophrenia 0.1 0.2 0.5 -0.1 -0.2 -0.6 -0.7 -0.0 -0.5 0.2 0.3
Depressed Affect (Nagel 2018) 0.3 0.6 3.3 -1.8 0.3 -0.5 -0.9 -0.5 -0.4 0.3 -0.0
Depression (Nagel 2018) 0.2 0.2 0.6 -0.7 0.5 -0.2 -0.4 0.8 0.0 -0.0 -0.6
Intelligence (Savage-Jansen 2018) 1.3 3.9 9.2 3.0 1.5 2.1 1.8 1.1 2.1 -1.4 -2.2
Neuroticism (Nagel 2018) 0.3 0.6 2.9 -1.7 0.3 -0.7 -0.6 0.4 -0.5 0.6 0.4
Schizophrenia (2018) 0.0 0.1 0.4 0.1 -0.1 0.0 0.2 0.3 0.2 -0.6 -0.4
Schizophrenia vs Biploar Disorder 0.5 0.7 1.1 1.1 0.4 0.6 0.9 -0.7 0.8 -0.9 -1.0
Worry (Nagel 2018) 0.4 0.8 1.6 -1.3 -0.5 -0.9 -0.7 0.5 -0.9 0.7 1.0
Alzheimer’s Disease (in mother) 0.2 0.3 1.1 -1.1 0.0 -0.2 -0.6 -0.4 -0.3 0.7 0.2
Alzheimer’s Disease (in father) 0.3 0.3 1.6 -1.3 0.2 -0.7 0.2 0.3 0.0 0.3 -0.3
Alzheimer’s Disease (including proxy) 0.6 0.8 3.3 -1.8 -0.3 -1.1 -0.7 -0.4 -0.6 0.9 0.3
Crohns Disease (2017) 0.1 0.3 1.0 -0.7 0.3 0.5 0.2 1.0 0.6 0.3 -0.3
Irritable Bowel Disease (IBD) 0.3 0.6 2.1 -0.4 0.3 0.8 0.7 1.4 1.1 -0.6 -0.4
Ulcerative Colitis (UC) 0.1 0.2 0.4 -0.2 -0.0 0.3 0.5 0.6 0.6 -0.5 0.3
Major Depression (MDD) 0.3 0.4 1.1 -1.0 0.7 -0.5 -0.0 -0.9 -0.0 -0.1 0.7
Reaction Time 1.3 2.4 3.8 -0.3 1.9 1.4 1.8 1.7 1.9 -1.2 -1.3
Verbal and Numeric Reasoning (VNR) 0.9 2.2 4.9 1.5 0.9 1.3 1.1 0.9 1.8 -1.7 -2.2
Breast Cancer 0.3 0.7 3.1 0.9 0.9 -0.3 -0.3 0.2 -0.5 1.8 0.7
Ovarian Cancer 0.1 0.1 0.8 0.9 -0.1 0.1 0.1 0.0 0.2 0.5 -0.2
Prostate Cancer 0.9 1.3 3.3 1.0 -0.6 0.8 1.0 0.8 1.1 -1.5 -1.8
Age at First Birth 0.3 0.4 1.2 -0.7 0.6 0.3 -0.8 -0.2 -0.4 0.4 1.1
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.1 0.2 0.6 -0.3 -0.4 -0.0 -0.6 0.8 -0.3 0.1 0.1
Coronary Artery Disease (CAD) 0.9 1.0 5.5 0.9 0.7 1.1 -0.0 -2.3 0.2 -0.0 -0.2
Crohns Disease (2012) 0.3 0.4 2.5 -1.6 -0.3 0.6 -0.1 -0.7 0.3 0.1 -0.1
Mean Putamen Volume 1.2 1.3 5.0 -2.2 -0.7 -1.5 -0.6 0.2 -0.9 1.0 0.9
Fasting Glucose 0.3 0.4 2.4 1.6 0.2 -0.1 -0.5 -0.5 -0.3 0.1 0.2
HbA1C 1.2 1.3 4.1 -0.1 1.3 2.0 1.5 -0.1 1.1 -0.8 -0.8
HDL Cholesterol 0.1 0.1 0.4 -0.1 -0.1 -0.7 0.2 0.2 -0.2 0.1 0.3
LDL Cholesterol 0.2 0.3 0.9 -0.4 -0.1 -0.1 -0.9 -0.8 -0.6 -0.2 0.4
Lupus 1.7 2.5 5.5 -0.1 0.5 2.4 1.8 0.1 2.0 -2.0 -1.8
Neuroticism (2016) 1.6 2.4 4.7 -1.7 -0.6 -1.6 -1.7 -0.3 -1.7 2.2 1.4
Primary Biliary Cirrhosis 2.4 3.4 5.6 2.4 1.5 2.2 1.8 2.1 1.9 -0.5 -1.6
Rheumatoid Arthritis 0.3 0.4 1.9 -0.1 0.4 1.4 0.4 0.4 0.7 -0.5 0.2
Schizophrenia (2014) 0.0 0.0 0.1 0.2 0.1 -0.2 0.0 0.1 0.0 -0.2 -0.4
Triglycerides 0.3 0.5 1.5 1.1 0.7 -0.3 -0.3 1.2 0.1 -0.5 -0.4
Type 2 Diabetes (T2D) (2012) 0.1 0.2 0.5 -0.6 0.7 0.1 -0.2 -0.5 -0.1 0.1 0.3
Ulcerative Colitis 0.8 1.1 3.1 -0.4 0.4 1.1 0.9 1.8 1.2 -1.2 -0.9
Blood Eosinophil Count 0.6 4.3 21.5 1.6 2.0 1.4 0.0 -4.6 -0.1 -1.1 1.8
Blood Platelet Count 0.3 3.8 22.0 1.5 4.7 -0.5 0.1 0.1 -0.5 1.2 2.0
Blood Red Count 0.2 1.5 3.1 -1.8 -1.5 -0.1 -1.4 -1.7 -1.2 0.4 0.3
Blood White Count 0.9 6.4 42.0 0.1 0.8 -2.7 -0.2 6.5 -0.4 1.1 -0.1
Heel T-Score 0.2 1.5 2.8 -1.2 -0.5 -1.1 -1.2 -1.3 -1.2 1.3 1.7
BMI 0.0 0.1 0.3 0.4 0.0 0.5 -0.3 -0.2 0.3 -0.5 -0.0
Height 0.4 7.1 15.4 0.3 1.6 1.7 3.1 2.8 2.9 -3.9 -3.2
Waist Hip Ratio (WHR) 0.4 1.7 4.8 0.4 2.2 1.3 -1.4 -1.7 -0.6 1.4 0.6
Systolic Blood Pressure 1.7 8.6 26.0 2.6 5.1 3.6 3.0 1.1 2.7 -2.0 -1.4
Smoking Status 0.1 0.2 0.6 0.0 0.6 0.5 -0.3 -0.1 0.5 -0.8 -0.4
Allergy or Eczema 0.7 1.7 2.8 1.7 1.3 1.3 1.1 -1.0 1.2 -1.4 -1.5
Cardiovascular Disease 0.7 2.3 12.0 0.6 3.5 2.1 0.3 0.2 0.7 0.1 1.2
Hypothyroidism (self reported) 0.4 1.0 3.4 -0.5 0.5 0.4 -0.2 -1.7 -0.6 0.6 1.8
Respiratory disease 0.6 1.3 6.4 -0.0 0.4 -0.1 -0.6 -2.5 -1.1 0.9 1.1
Type 2 Diabetes (T2D) (2018) 0.1 0.2 0.8 -0.1 0.9 0.5 -0.4 0.1 -0.1 0.0 0.6
Lung FEV1/FVC ratio 0.2 0.8 2.4 -0.6 0.5 0.2 0.9 1.5 0.8 -0.2 -1.4
Lung FVC 0.8 4.3 10.9 -2.0 -2.6 -3.3 -1.7 -0.6 -2.2 1.2 1.6
Neuroticism 0.4 1.1 1.8 -1.3 -0.6 -1.1 -1.3 -0.8 -1.1 0.9 0.8
Chronotype (morning person) 0.2 0.5 1.8 -0.3 1.3 0.5 0.1 0.6 0.5 -0.8 -0.7
Hair Pigment 0.0 0.8 4.0 -0.1 -2.0 -0.6 -0.8 -0.2 -0.6 1.0 -0.0
Tanning 0.0 0.2 0.8 -0.4 0.1 -0.3 -0.1 0.1 0.2 -0.9 -0.4
Hand grip strength (left) 0.1 0.3 1.6 -0.5 -0.3 -0.2 0.1 -1.3 -0.0 -0.6 -0.4
Number of treatments/medications taken 0.6 1.0 6.1 -0.1 2.5 1.1 0.3 0.4 0.5 0.0 -0.4
Average weekly spirits intake 1.4 1.7 3.2 0.6 1.8 1.7 1.7 -0.1 1.4 -1.1 -1.2
Sensitivity / hurt feelings 0.6 1.0 2.4 -1.6 -0.2 -1.2 -1.1 -0.1 -1.1 1.0 0.8
Frequency of depressed mood in last 2 weeks 0.2 0.2 0.8 -0.9 -0.2 -0.2 -0.8 -0.1 -0.3 0.1 -0.4
Hearing difficulty/problems: Yes 1.4 2.2 3.3 -1.1 -1.8 -1.0 -1.5 -1.8 -1.7 1.5 1.1
Relative age of first facial hair 0.2 0.5 1.3 -0.1 -0.1 -0.6 -0.6 0.8 -0.1 1.2 -1.1
Other serious medical condition/disability diagnosed by doctor 0.1 0.1 0.5 0.7 0.0 -0.3 0.2 -0.2 -0.3 -0.2 0.6
Ever used hormone-replacement therapy (HRT) 0.2 0.2 0.6 0.8 0.6 0.2 -0.2 0.4 0.0 0.3 -0.8
Ever had hysterectomy (womb removed) 2.5 2.8 4.5 0.6 2.1 1.6 2.0 0.7 1.8 -1.9 -2.0
Systolic blood pressure, automated reading 1.0 3.0 12.2 1.6 3.5 2.0 1.5 0.7 1.4 -0.3 -0.8
Eye problems/disorders: Diabetes related eye disease 0.6 0.6 3.1 -0.4 0.5 0.8 -0.1 1.8 0.5 -0.3 -0.4
Angina 0.3 0.4 2.7 -0.1 1.6 0.8 0.0 -0.3 0.2 0.1 -0.2
Medication for hormone replacement therapy 0.4 0.5 1.0 0.7 0.7 0.2 0.5 1.0 0.7 -0.6 -0.7
Vitamin and mineral supplements 0.9 1.2 2.9 -1.7 -0.6 -0.4 -1.0 -0.3 -1.1 1.1 1.6
Supplements: Zinc 0.3 0.3 1.7 0.1 -0.3 0.3 0.4 -1.3 0.1 -0.4 -0.3
Medication: Co-codamol 0.1 0.2 0.6 0.1 0.3 0.6 -0.8 -0.2 -0.0 -0.4 0.3
Medication: Metformin 0.5 0.7 1.2 -1.1 -0.3 -0.2 -0.9 -0.9 -0.8 1.1 0.8
Diabetes (father) 0.5 0.6 1.1 -0.9 -0.6 -1.0 -0.7 0.6 -0.6 0.7 1.1
Diabetes (mother) 0.0 0.1 0.3 0.0 0.2 -0.1 0.1 0.3 -0.1 -0.1 0.5
Severe depression (siblings) 2.1 2.4 4.4 2.0 0.9 1.1 2.1 0.5 1.7 -2.0 -1.2
Pack years adult smoking proportion 0.4 0.6 1.3 -0.4 -1.1 -1.0 -1.2 -0.4 -0.9 0.1 0.4
Impedance of leg (right) 1.3 6.3 21.0 0.5 4.6 3.8 2.4 0.6 2.5 -0.6 -1.6
Leg fat-free mass (left) 0.2 1.0 4.0 0.5 -2.0 -1.1 -0.5 -0.2 -0.2 -1.4 -0.0
Trunk fat percentage 0.6 2.3 6.9 1.5 2.6 2.3 0.9 0.1 1.4 -0.7 -0.7
Hand grip strength (right) 0.3 0.7 2.2 0.3 -1.5 -1.0 -0.6 -1.1 -0.7 0.7 0.1
Townsend deprivation index at recruitment 1.4 2.0 4.0 -1.3 -1.1 -1.5 -1.7 0.4 -1.5 2.0 1.2
Current tobacco smoking 0.3 0.4 1.4 0.4 0.3 0.6 0.4 -0.4 0.7 -1.2 -0.8
Average weekly fortified wine intake 0.2 0.2 0.8 -0.2 0.8 0.9 0.4 0.1 0.2 -0.0 0.2
Maternal smoking around birth 0.2 0.3 0.9 -0.9 0.9 0.6 -0.6 -0.3 0.0 0.3 -0.1
Fed-up feelings 0.2 0.3 1.8 -1.4 0.4 0.2 -0.2 -0.4 0.0 -0.1 -0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 1.5 -0.6 -0.4 -0.7 -0.7 1.2 -0.1 0.2 -0.1
Relative age voice broke 0.6 0.9 3.0 -0.0 1.4 0.7 0.6 0.5 1.0 0.2 -1.7
Taking other prescription medications 0.5 0.8 3.1 0.3 1.8 1.4 0.2 -0.6 0.6 -0.3 -0.3
Age when periods started (menarche) 1.5 3.5 9.2 2.2 0.9 0.8 1.8 3.0 1.5 -1.5 -2.3
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 1.2 1.1 1.0 0.5 1.0 -0.3 0.5 -0.3 -0.8
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.5 3.1 -1.8 -0.9 -1.4 -1.5 -0.1 -1.3 1.1 1.0
Tinnitus: Yes, but not now, but have in the past 0.1 0.1 0.2 -0.3 -0.2 0.1 -0.4 0.2 -0.2 -0.3 0.2
Qualifications: CSEs or equivalent 0.6 0.8 2.8 0.7 -1.1 -1.7 -1.0 -0.3 -0.8 -0.1 0.6
Serious illness, injury or assault to yourself 0.6 0.7 1.4 0.1 -0.6 -0.6 -0.7 -1.1 -1.1 1.2 1.0
High blood pressure 1.4 4.0 17.1 1.0 4.1 2.8 1.2 1.1 1.7 -0.7 -0.3
Hayfever, allergic rhinitis or eczema 1.3 2.9 5.2 1.7 1.7 1.6 1.6 -0.7 1.7 -2.3 -1.9
Multivitamins +/- minerals 0.4 0.4 1.8 1.4 -0.3 -0.5 0.5 0.4 0.3 -0.4 -0.9
Stomach or abdominal pain in last month 0.1 0.1 0.3 0.2 0.3 -0.2 -0.3 0.6 -0.1 -0.1 0.5
Supplements: Glucosamine 2.4 3.2 5.8 -1.3 -2.1 -1.8 -2.4 -1.5 -2.0 1.0 1.6
Diverticular disease/diverticulitis (self-reported) 0.8 0.9 2.4 -0.1 -0.0 1.5 0.9 -0.9 0.9 -1.5 -0.7
Medication: Atenolol 0.6 0.8 4.3 0.4 2.1 0.8 0.3 0.9 0.4 -0.2 -0.1
Medication: Levothyroxine sodium 0.3 0.4 1.8 -0.3 0.5 0.5 -0.3 -1.4 -0.2 0.5 0.9
Sitting height 0.1 0.4 1.0 -0.6 -1.0 -0.5 -0.4 -0.9 -0.6 0.1 0.6
Chronic bronchitis/emphysema (father) 1.3 1.6 3.4 0.2 1.5 1.9 1.5 -0.7 1.5 -1.1 -0.8
High blood pressure (mother) 0.7 1.0 4.5 -1.5 0.1 -0.1 -0.2 -2.1 -0.5 0.7 0.6
Body mass index (BMI) 0.1 0.4 1.1 0.1 -0.6 -0.5 -1.0 -0.8 -0.6 0.2 0.8
Impedance of leg (left) 1.3 6.1 21.4 0.7 4.6 3.5 2.3 1.0 2.4 -0.3 -1.8
Leg predicted mass (left) 0.2 1.0 3.8 0.6 -2.0 -1.0 -0.4 -0.2 -0.1 -1.5 -0.1
Trunk fat mass 0.4 1.6 3.4 1.3 1.8 1.9 0.9 0.1 1.3 -1.1 -0.9
Waist circumference 0.1 0.4 1.0 0.8 0.5 0.5 -0.9 -1.0 -0.3 -0.1 0.5
Number of incorrect matches in round 0.4 0.6 1.6 0.4 0.1 -0.3 -1.0 1.1 -0.9 0.5 1.3
Past tobacco smoking 0.2 0.4 1.3 -0.7 -1.1 -0.9 0.2 -0.1 -0.6 0.3 0.4
Alcohol usually taken with meals 0.4 0.6 1.1 0.5 1.0 0.9 1.1 0.2 0.6 -1.0 -0.0
Nervous feelings 0.2 0.3 1.4 -0.3 0.5 -0.2 -0.3 -0.3 -0.3 1.2 0.5
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 1.2 -0.2 -0.6 -0.7 -1.1 0.5 -0.7 0.9 0.7
Hearing difficulty/problems with background noise 2.0 3.2 5.3 -1.8 -1.7 -2.3 -1.6 -1.1 -2.1 2.3 1.2
Hair/balding pattern: Pattern 2 1.9 2.4 3.3 -1.3 -1.5 -1.7 -1.8 -1.5 -1.6 1.6 1.5
Had menopause 0.1 0.1 0.4 0.6 0.6 0.3 0.3 0.0 0.0 -0.4 -0.3
Had other major operations 1.9 2.3 5.5 1.7 1.4 0.7 1.0 1.5 1.4 -2.3 -1.5
Forced vital capacity (FVC) 0.5 1.9 4.3 -1.7 -2.1 -1.8 -1.6 -0.1 -1.2 0.7 0.9
Heel bone mineral density (BMD) T-score, automated (right) 0.4 1.0 2.0 -1.4 -0.2 -1.4 -1.4 0.5 -1.0 0.6 0.7
Ever unenthusiastic/disinterested for a whole week 0.4 0.4 0.8 0.8 -0.8 -0.9 -0.4 -0.3 -0.7 0.1 0.8
Qualifications: None of the above 0.7 1.5 2.9 -1.6 -0.6 -1.4 -1.6 -0.1 -1.3 1.7 0.8
Financial difficulties in last 2 years 3.2 4.4 7.2 -1.4 -1.7 -2.7 -2.4 -1.4 -2.5 2.3 1.9
Mouth/teeth dental problems 0.8 1.2 2.2 -0.7 -1.2 -1.3 -0.7 -0.2 -1.2 1.5 1.4
Heart attack 1.7 2.2 4.6 0.6 2.1 1.8 1.4 1.5 1.4 -1.5 -1.1
Allergy 0.4 0.9 4.7 -0.5 -1.1 -0.7 0.3 2.2 -0.1 0.3 0.2
Pain all over the body in last month 2.7 2.9 5.8 -1.7 -1.2 -1.6 -1.8 -2.4 -1.5 1.7 1.6
Diabetes (self-reported) 0.3 0.4 1.5 0.4 0.9 1.2 -0.1 0.1 -0.2 0.6 0.7
Hayfever/allergic rhinitis (self-reported) 2.1 2.8 4.4 2.1 1.8 1.5 2.1 0.1 1.8 -1.3 -1.9
Medication: Ramipril 0.7 0.9 2.8 -1.7 1.2 0.9 0.5 1.1 0.7 -0.3 -0.4
Medication: Simvastatin 0.7 1.0 2.0 -0.0 -0.1 -0.2 -1.3 -1.3 -1.0 1.4 1.3
Fluid intelligence score 0.3 0.6 1.5 0.9 0.4 0.8 0.8 -0.4 1.0 -0.5 -1.2
Illnesses of siblings 0.3 0.4 2.5 0.1 -1.6 -0.4 -0.1 -0.2 -0.3 -0.1 0.1
Neuroticism score 0.3 0.7 1.5 -0.8 -0.3 -0.8 -1.2 -0.5 -0.9 1.0 0.7
Weight 0.1 0.4 1.4 1.0 -0.2 0.3 0.1 -0.1 0.5 -1.2 -0.4
Impedance of arm (right) 1.5 6.8 18.3 1.8 4.3 4.0 2.5 0.5 2.5 -1.4 -1.4
Arm fat percentage (right) 0.3 1.0 3.1 0.8 1.7 1.8 0.5 -0.4 0.9 -0.6 -0.2
Trunk fat-free mass 0.2 1.1 3.7 0.6 -1.6 -0.7 0.3 0.2 0.5 -1.9 -1.1
Hip circumference 0.1 0.4 1.5 1.0 -0.4 -0.1 0.2 0.2 0.4 -1.2 -0.2
Time employed in main current job 1.4 1.7 3.4 1.0 1.0 1.5 1.8 1.2 1.5 -0.9 -1.0
Alcohol intake versus 10 years previously 2.3 3.4 8.0 -1.5 -1.3 -1.9 -2.0 -0.9 -2.0 2.8 1.7
Father’s age at death 3.3 4.4 7.1 1.4 1.7 1.6 2.5 2.1 2.3 -2.7 -2.2
Worrier / anxious feelings 0.5 0.9 2.2 -1.2 -0.6 -0.8 -1.1 -0.2 -1.2 0.6 1.5
Frequency of tiredness / lethargy in last 2 weeks 0.6 0.9 2.2 1.5 0.7 1.3 0.5 0.1 1.0 -1.1 -0.9
Falls in the last year 1.5 2.0 3.3 -1.2 -1.7 -1.0 -1.8 -0.8 -1.6 1.5 1.3
Hair/balding pattern: Pattern 3 0.7 1.1 2.9 -1.6 -0.2 -0.7 -0.4 -1.1 -0.9 1.7 0.8
Number of live births 0.8 1.1 4.4 2.0 0.3 -0.2 0.4 2.1 0.2 -0.4 0.1
Forced expiratory volume in 1-second (FEV1) 0.4 1.4 2.7 -1.6 -1.6 -1.5 -1.3 -0.3 -0.9 0.6 0.7
Pulse rate 0.5 0.8 2.0 0.4 1.2 1.4 0.8 -0.2 1.0 -0.4 -1.1
Happiness 0.8 1.0 2.4 0.1 -1.4 -1.6 -0.6 -0.9 -1.1 0.4 0.9
Noisy workplace 0.3 0.4 1.5 -0.1 0.0 -0.5 -0.8 0.5 -0.5 1.2 -0.3
Qualifications: A levels/AS levels or equivalent 0.1 0.3 1.2 1.1 -0.2 0.4 0.2 0.4 0.4 -0.5 0.0
Serious illness, injury or assault of a close relative in last 2 years 1.1 1.2 3.4 1.8 0.7 1.0 1.4 0.0 1.2 -0.3 -1.2
Mouth/teeth dental problems: Dentures 0.3 0.5 1.5 0.0 1.0 1.2 -0.1 0.8 0.4 -0.4 -0.8
Asthma 0.5 0.9 3.7 0.7 1.2 0.8 -0.4 -1.9 -0.6 0.5 0.7
Medication: Ibuprofen (e.g. Nurofen) 3.2 4.0 7.0 -1.8 -1.3 -2.6 -2.6 0.0 -2.4 2.0 1.9
Medication: Cholesterol lowering 2.0 3.2 5.7 2.3 2.4 2.4 1.3 1.0 1.8 -1.2 -1.3
Depression (self-reported) 1.6 1.9 3.5 -0.7 -1.3 -1.5 -1.4 -0.9 -1.6 1.4 1.9
Medication: Lansoprazole 0.9 1.0 1.5 -0.7 -0.9 -1.2 -1.2 -0.5 -1.1 0.9 1.2
Prospective memory result 0.7 0.8 2.2 -0.8 -0.7 -0.4 -1.5 -0.1 -0.9 1.3 0.9
Lung cancer (father) 0.3 0.3 1.0 0.6 -0.4 -0.6 0.1 -1.0 -0.4 0.3 -0.7
Illnesses of mother 0.9 1.1 2.7 0.4 -1.6 -1.3 -1.4 0.5 -0.9 0.8 0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.4 1.0 -0.9 -1.0 -1.0 -0.2 0.1 -0.1 -0.0 -0.2
Pulse wave Arterial Stiffness index 0.8 1.0 3.7 1.1 0.9 1.1 0.0 -1.9 0.4 -0.9 -0.4
Impedance of arm (left) 1.2 5.6 14.9 1.9 3.9 3.4 2.3 1.3 2.3 -1.0 -1.2
Arm fat mass (right) 0.1 0.3 0.8 0.7 0.6 0.9 0.0 -0.5 0.4 -0.7 -0.1
Trunk predicted mass 0.2 1.1 3.6 0.6 -1.7 -0.7 0.3 0.2 0.5 -1.9 -1.1
Standing height 0.4 4.1 8.9 1.8 0.8 1.4 2.1 1.4 2.2 -3.0 -2.5
Length of working week for main job 0.5 0.6 3.6 -0.5 -0.4 -0.4 -0.3 1.9 -0.0 0.7 -0.2
Exposure to tobacco smoke at home 0.3 0.3 1.8 0.1 -0.5 0.0 -0.6 1.3 0.1 -0.2 -0.5
Breastfed as a baby 0.2 0.3 1.9 -0.2 -0.6 -0.1 0.1 1.4 0.2 -0.2 -0.0
Tense / ‘highly strung’ 0.5 0.8 2.0 -1.4 -0.5 -0.9 -0.8 1.1 -0.7 0.9 0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 1.2 1.8 3.3 -0.2 -1.6 -1.5 -1.8 0.2 -1.7 1.2 1.4
Hair/balding pattern: Pattern 4 1.1 2.6 3.7 1.5 1.9 1.2 1.7 1.3 1.9 -1.5 -1.7
Birth weight of first child 0.2 0.4 1.2 1.1 0.1 0.8 0.3 0.2 0.7 -0.6 -0.6
Peak expiratory flow (PEF) 0.7 1.5 2.4 -1.5 -1.5 -1.0 -1.5 -1.2 -1.2 0.6 1.2
Pulse wave reflection index 0.6 0.8 3.9 0.7 0.2 0.5 -0.6 -2.0 -0.6 0.2 0.9
Ever highly irritable/argumentative for 2 days 0.3 0.4 1.4 0.4 -1.2 -0.7 -0.4 -0.2 -0.6 0.6 0.2
Loud music exposure frequency 2.9 3.2 4.6 2.1 1.1 1.9 1.5 1.7 1.7 -1.9 -2.1
Qualifications: O levels/GCSEs or equivalent 0.9 1.4 6.0 2.4 0.6 1.2 0.6 0.7 1.1 -1.2 -0.3
Mouth/teeth dental problems: Bleeding gums 3.9 5.0 8.7 2.1 1.9 1.7 2.6 0.4 2.5 -3.0 -2.7
Blood clot in the leg (DVT) 1.0 1.3 3.2 0.3 -1.2 -0.8 -1.8 -0.6 -1.4 1.0 1.3
Medication: Paracetamol 0.5 0.9 2.2 -1.5 0.4 -1.0 -1.2 -0.1 -1.1 0.6 0.8
Headache pain in last month 0.4 0.7 1.3 1.0 1.2 0.2 0.8 1.1 0.7 -0.7 -0.9
Medication for cholesterol, blood pressure or diabetes 1.0 1.7 4.4 -1.7 -2.1 -2.0 -0.5 0.1 -1.2 0.5 0.2
Glaucoma (self-reported) 2.9 3.4 5.9 -0.6 2.4 2.4 1.6 1.5 2.1 -1.6 -1.8
Gout (self-reported) 0.4 0.6 2.7 -1.6 -0.4 -0.2 -0.6 0.6 -0.3 0.7 0.7
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 3.5 -1.0 -0.3 0.3 -0.7 -1.8 -0.9 0.8 1.9
Medication: Amlodipine 0.9 1.3 3.6 1.3 1.8 1.9 0.1 -0.6 0.7 -0.8 0.6
Medication: Ventolin 100micrograms inhaler 0.3 0.3 1.0 0.0 -0.3 -0.1 -0.9 -0.3 -0.6 1.0 0.5
Birth weight 0.4 0.9 2.6 -0.4 -1.5 -1.6 -0.9 0.3 -0.8 0.5 0.8
Chronic bronchitis/emphysema (mother) 1.7 2.0 4.2 1.2 1.5 2.0 1.5 0.7 1.6 -0.6 -1.6
High blood pressure (siblings) 1.1 1.5 5.7 0.6 2.4 1.3 1.0 0.1 1.3 -1.2 -0.5
Forced vital capacity (FVC), Best measure 0.1 0.2 0.8 -0.6 -0.9 -0.6 -0.2 0.2 -0.0 -0.4 -0.2
Body fat percentage 0.5 1.9 6.4 1.1 2.5 2.1 0.9 -0.0 1.3 -0.6 -0.5
Leg fat percentage (right) 0.2 0.7 3.0 0.1 1.7 1.5 0.3 -0.4 0.6 -0.0 0.2
Arm fat-free mass (right) 0.2 1.0 3.9 0.2 -2.0 -1.4 -0.3 0.5 -0.1 -1.1 -0.4
Exposure to tobacco smoke outside home 0.2 0.3 0.8 -0.5 -0.7 0.0 -0.3 0.9 0.4 -0.4 -0.5
Comparative body size at age 10 0.9 2.6 4.9 -1.1 -2.2 -1.4 -1.7 -1.8 -1.8 0.8 1.6
Number of full brothers 0.4 0.6 1.5 1.2 0.9 0.4 0.6 0.4 0.6 -0.7 -0.8
Worry too long after embarrassment 0.1 0.2 0.8 0.4 0.4 -0.3 0.2 0.1 -0.2 0.9 -0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 4.0 0.4 -0.5 -0.3 -0.1 2.0 -0.1 -0.6 -0.1
Wheeze or whistling in the chest in last year 0.2 0.3 0.8 -0.4 0.9 -0.4 -0.4 -0.6 -0.6 0.2 0.5
Number of children fathered 0.5 0.6 2.2 -1.5 -0.9 -0.1 -0.8 -0.3 -0.6 0.5 0.8
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 1.1 0.2 0.4 0.4 0.1 -1.0 -0.1 0.2 -0.2
Age at first live birth 0.2 0.3 0.9 0.9 0.9 0.4 0.5 -0.3 0.5 -0.5 -0.0
Pulse wave peak to peak time 0.7 0.8 4.0 -0.8 -0.9 -0.9 0.1 2.0 -0.2 0.7 0.1
Health satisfaction 0.4 0.5 1.2 1.1 1.0 0.8 0.5 0.0 0.6 -0.4 -0.3
Shortness of breath walking on level ground 0.3 0.4 0.7 0.3 0.5 0.6 0.7 0.4 0.7 -0.7 -0.8
Qualifications: College or University degree 0.4 1.3 2.5 1.3 0.6 1.5 1.6 0.6 1.2 -0.6 -1.1
Eye problems/disorders: None of the above 2.1 2.5 8.7 0.1 -1.5 -1.0 -1.3 -3.0 -1.4 0.7 2.0
Mouth/teeth dental problems: Loose teeth 0.4 0.5 1.0 -0.7 -0.5 -0.7 -1.0 -0.9 -0.7 0.6 0.5
Emphysema/chronic bronchitis 0.2 0.2 0.6 -0.0 0.5 0.3 -0.0 0.7 0.2 -0.7 -0.5
Medication for pain relief, constipation, heartburn 0.3 0.6 1.4 0.5 -0.8 0.1 1.2 1.1 0.8 -0.3 -0.5
Neck or shoulder pain in last month 0.6 0.8 2.0 -1.4 -0.9 -0.7 -0.6 -0.6 -1.1 0.8 0.8
Medication: Blood pressure 0.8 1.4 4.0 1.3 1.9 2.0 0.7 0.3 1.2 -0.4 0.0
Angina (self-reported) 0.4 0.6 3.4 -0.0 1.8 0.9 0.2 -0.2 0.3 -0.2 -0.2
Migraine (self-reported) 0.4 0.5 1.3 -0.1 0.7 0.5 0.8 -0.4 0.5 -1.1 -0.7
Medication: Ibuprofen 0.7 0.9 2.4 -0.5 0.0 -1.6 -1.1 1.0 -1.0 0.9 0.5
Medication: Allopurinol 0.2 0.3 1.2 -1.1 -0.1 -0.2 0.0 -0.7 -0.2 0.1 0.5
Medication: Omeprazole 0.4 0.5 1.3 0.1 -0.1 -0.8 -1.1 -0.5 -0.8 0.8 0.9
Medication: Seretide 50 evohaler 1.9 2.2 4.0 -0.0 -0.6 -1.3 -1.3 -1.8 -1.8 1.8 2.0
Mean time to correctly identify matches 1.3 2.4 4.0 0.0 2.0 1.7 1.8 1.6 1.9 -1.0 -1.4
Heart disease (mother) 0.2 0.3 1.1 -1.0 -0.2 0.5 -0.2 -0.4 -0.5 0.0 0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.1 1.3 2.0 -1.4 -1.2 -1.1 -1.2 -0.9 -1.2 0.6 1.3
Whole body fat mass 0.2 0.9 2.2 0.8 1.5 1.5 0.6 -0.1 1.0 -0.9 -0.6
Leg fat mass (right) 0.1 0.4 1.3 0.4 0.8 1.1 0.3 -0.3 0.7 -0.7 -0.3
Arm predicted mass (right) 0.2 0.8 3.5 -0.0 -1.9 -1.3 -0.4 0.2 -0.2 -0.9 -0.4
Pulse rate, automated reading 1.3 4.1 10.6 0.2 2.3 3.3 1.6 -2.1 1.9 -2.0 -1.6
Alcohol intake frequency. 1.2 2.9 5.3 -1.4 -1.2 -1.8 -2.0 -1.1 -2.2 1.1 2.3
Comparative height size at age 10 0.2 1.1 2.9 0.0 0.1 0.3 1.4 1.3 1.2 -1.7 -1.1
Number of full sisters 0.6 0.7 1.4 -1.2 -0.7 -1.1 -1.0 1.0 -0.7 0.2 0.1
Suffer from ‘nerves’ 0.7 1.2 1.9 -0.7 -1.4 -1.3 -1.1 -0.3 -1.3 1.2 0.8
Overall health rating 0.2 0.4 1.3 0.1 1.0 0.4 -0.4 -1.2 -0.1 -0.7 0.3
Chest pain or discomfort 3.1 4.4 8.1 -2.2 -1.1 -1.4 -1.7 -2.9 -2.2 2.6 2.1
Had major operations 0.3 0.3 0.8 -0.2 -0.8 0.1 -0.8 0.9 -0.0 0.5 -0.2
Age at last live birth 0.5 0.8 2.5 1.6 0.8 0.7 0.6 -1.1 0.2 -0.9 0.3
Family relationship satisfaction 0.4 0.4 1.2 0.4 -0.2 0.3 1.1 -0.6 0.8 -0.7 -0.7
Leg pain on walking 0.6 0.7 1.7 -0.5 -0.3 -0.7 -1.3 1.1 -0.8 0.8 0.9
Qualifications: NVQ or HND or HNC or equivalent 2.8 3.4 7.4 -2.7 -1.6 -2.0 -2.0 -1.2 -1.9 1.0 1.9
Commuting to job workplace: Car/motor vehicle 2.0 2.3 3.8 -2.0 -0.6 -1.8 -1.4 -1.5 -1.6 1.2 1.6
Illness, injury, bereavement, stress in last 2 years 2.7 3.3 7.6 1.2 1.6 1.5 1.5 2.8 1.9 -2.2 -1.4
Medication: Aspirin 1.5 1.9 5.3 1.7 1.3 2.3 1.2 -0.4 1.1 -1.3 -1.1
Supplements: Vitamin C 1.7 2.0 4.5 0.5 1.2 1.4 1.3 -0.3 1.7 -2.1 -1.7
Knee pain experienced in last month 0.0 0.1 0.2 -0.3 -0.1 0.0 -0.5 -0.3 -0.0 0.2 -0.2
Hypertension (Self-reported) 1.5 4.2 17.0 1.1 4.1 2.9 1.4 1.2 1.8 -0.8 -0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.2 0.4 0.5 0.3 -0.6 -0.5 -0.4 -0.5 0.0 0.5
Illnesses of father: Heart disease 0.3 0.5 1.5 -0.3 0.1 0.1 -1.1 -1.2 -0.5 0.8 0.1
Illnesses of siblings: Diabetes 0.3 0.3 1.0 -0.1 0.3 -0.5 -0.5 0.4 -0.6 1.0 0.7
Smoking status: Previous 0.3 0.5 1.9 0.4 1.4 1.1 0.0 -0.0 0.6 -0.4 -0.3
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.3 0.8 0.0 -0.4 0.1 0.2 -0.7 0.6 -0.4 -0.9
Whole body fat-free mass 0.2 1.0 3.8 0.6 -2.0 -1.0 -0.1 0.0 0.1 -1.6 -0.7
Leg fat-free mass (right) 0.3 1.4 6.0 0.5 -2.4 -1.6 -0.8 -0.1 -0.5 -1.1 0.1
Arm fat percentage (left) 0.1 0.5 1.6 0.6 1.2 1.3 0.1 -0.2 0.5 -0.2 0.2
Average weekly red wine intake 0.4 0.5 1.6 -0.2 -0.2 1.2 1.3 -0.3 0.7 -0.4 -0.5
Handedness (chirality/laterality): Left-handed 0.9 1.1 1.6 0.7 1.2 1.0 1.1 0.2 1.2 -1.1 -1.3
Mood swings 0.4 0.6 2.6 -1.6 0.4 -1.0 -0.5 1.0 -0.3 0.1 0.3
Loneliness, isolation 0.3 0.4 1.7 -1.3 -0.0 0.3 -0.6 -0.7 -0.4 0.5 0.1
Long-standing illness, disability or infirmity 0.2 0.3 1.0 -0.1 0.8 0.5 -0.1 1.0 0.1 -0.3 0.1
Ever had bowel cancer screening 0.6 0.7 2.3 0.6 0.4 1.5 0.8 0.4 1.0 -0.7 -0.7
Diabetes diagnosed by doctor 0.2 0.4 0.7 0.0 0.8 0.7 -0.7 0.3 -0.5 0.7 0.8
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 1.0 0.4 -0.4 1.0 -0.1 0.1 0.4 -0.1 -0.3
Friendships satisfaction 0.2 0.3 1.3 0.0 -0.2 -0.6 0.4 -1.1 -0.2 0.6 0.0
Qualifications: nursing, teaching 0.9 1.4 3.9 1.3 1.0 0.3 1.5 1.0 1.1 -2.0 -0.5
Commuting to job workplace: Walk 0.3 0.3 0.9 -0.1 -0.9 -0.8 -0.6 -0.2 -0.5 0.6 0.6
Eye problems/disorders: Cataract 0.8 0.9 5.8 0.5 0.1 -0.3 0.7 2.4 0.3 0.1 -0.8
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 1.4 -0.5 -0.7 -1.2 -0.9 0.4 -0.4 0.0 0.6
Medication for cholesterol 0.3 0.5 2.1 0.5 -1.5 -0.7 0.0 0.6 0.1 -0.6 -0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.2 1.4 2.7 0.9 1.5 1.6 1.2 0.2 1.4 -0.5 -1.3
Back pain experienced in last month 0.9 1.3 4.3 -2.1 -0.4 0.6 -0.8 -1.3 -0.7 0.9 1.5
Mineral and other dietary supplements 0.2 0.3 0.8 0.9 0.6 0.5 0.6 0.5 0.5 -0.2 -0.0
Breast cancer (self-reported) 0.4 0.4 2.1 -0.2 -0.3 0.3 0.5 -0.6 0.5 -0.6 -1.4
Asthma (self-reported) 0.6 1.3 5.6 0.5 1.1 0.7 -0.7 -2.4 -0.8 0.9 0.9
Osteoporosis (self-reported) 0.2 0.3 0.6 0.4 -0.2 -0.7 -0.7 -0.1 -0.8 0.3 0.5
Osteoarthritis (self-reported) 0.4 0.5 1.1 -0.4 -0.1 -0.8 -1.1 0.1 -0.9 0.6 0.7
Medication: Aspirin 1.9 2.5 6.3 2.2 1.5 2.5 1.3 0.3 1.3 -1.4 -1.2
Medication: Gliclazide 1.4 1.6 3.0 1.4 1.3 1.7 1.6 0.1 1.4 -0.8 -1.0
Illnesses of father: None of the above (group 1) 1.3 1.7 6.7 0.2 -2.6 -1.6 -0.9 0.3 -1.4 0.9 0.6
Smoking status: Current 0.3 0.4 1.2 0.6 0.3 0.6 0.4 -0.2 0.7 -1.1 -0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 2.5 0.2 0.4 -0.2 0.9 1.6 0.6 -0.4 -1.1
Whole body water mass 0.2 1.1 4.3 0.4 -2.1 -1.1 -0.2 0.0 -0.0 -1.5 -0.6
Leg predicted mass (right) 0.3 1.4 6.1 0.6 -2.5 -1.6 -0.8 -0.1 -0.6 -1.1 0.1
Arm fat mass (left) 0.1 0.3 0.7 0.6 0.7 0.8 0.0 0.0 0.5 -0.6 -0.2
Number of self-reported non-cancer illnesses 0.5 0.9 4.1 0.4 2.0 0.9 -0.6 -0.5 -0.3 0.9 0.4
Average weekly champagne plus white wine intake 0.2 0.2 0.7 0.8 0.5 0.1 -0.3 -0.9 -0.1 0.0 0.3
Miserableness 0.2 0.4 1.8 -0.0 0.3 0.7 0.5 0.3 0.8 -0.4 -1.3
Guilty feelings 0.1 0.2 0.4 -0.3 0.3 -0.0 -0.5 0.5 -0.2 0.6 0.4
Wears glasses or contact lenses 2.2 2.5 7.1 1.5 1.4 0.9 1.4 2.7 1.4 -1.4 -1.5
Ever taken oral contraceptive pill 0.2 0.2 1.2 0.1 -0.2 0.4 -0.0 -0.1 0.5 -0.2 -1.1
Hearing aid user 0.9 1.0 3.8 -0.6 -0.8 -0.4 -1.0 0.4 -1.0 2.0 1.0
Mother’s age at death 5.2 6.4 11.2 2.1 2.5 3.4 2.7 -0.4 2.8 -1.9 -3.2
Financial situation satisfaction 0.2 0.2 0.6 -0.8 0.1 -0.2 -0.2 0.3 -0.3 0.5 0.7
Tinnitus: Yes, now most or all of the time 0.2 0.2 0.8 -0.3 0.6 -0.1 0.3 -0.3 0.1 -0.9 -0.0
Commuting to job workplace: Public transport 0.2 0.2 0.8 0.2 0.1 0.9 -0.1 -0.9 0.1 0.3 0.3
Eye problems/disorders: Glaucoma 3.0 3.5 7.5 -0.6 2.7 2.5 1.7 1.3 2.1 -1.6 -1.7
Medication: Blood pressure 0.7 1.2 7.0 -0.4 2.7 1.3 0.4 -0.0 0.3 0.1 0.9
Pain type(s) experienced in last month: Hip pain 0.9 1.2 2.1 -1.3 -0.2 0.2 -1.4 -1.4 -1.2 0.9 1.2
Supplements: Fish oil (including cod liver oil) 0.2 0.3 0.9 -1.0 0.3 -0.4 -0.5 -0.6 -0.5 0.8 -0.0
High cholesterol (Self-reported) 0.4 0.7 1.5 0.8 0.2 -0.1 -1.1 -0.5 -0.7 1.2 1.1
Medication: Bendroflumethiazide 0.8 1.3 4.7 0.6 2.2 1.8 0.7 0.8 0.8 0.3 0.1
Medication: Paracetamol 0.5 0.7 2.2 -1.5 0.8 -0.9 -0.6 0.3 -0.8 0.5 0.8
Medication: Lisinopril 0.6 0.7 1.6 0.7 -0.2 -0.3 -1.2 0.3 -1.1 1.1 1.1
Medication: Atorvastatin 1.6 2.0 3.8 1.3 1.9 2.0 1.1 0.3 1.5 -0.9 -1.5
Illnesses of father: High blood pressure 0.2 0.3 1.5 0.3 1.2 0.2 -0.1 -0.7 0.1 -0.1 0.5
Alcohol drinker status: Never 0.2 0.2 0.8 0.4 0.2 -0.2 -0.9 -0.0 -0.6 0.5 0.4
Ever smoked 0.0 0.1 0.4 -0.5 -0.0 0.0 -0.6 0.1 -0.0 0.1 0.2
Basal metabolic rate 0.1 0.7 2.5 0.5 -1.6 -0.8 -0.2 -0.1 0.1 -1.4 -0.5
Leg fat percentage (left) 0.1 0.5 2.6 0.2 1.6 1.1 0.1 -0.3 0.4 0.2 0.2
Arm fat-free mass (left) 0.1 0.6 2.1 0.4 -1.4 -0.8 -0.2 -0.1 0.1 -1.2 -0.6
Number of operations (self-reported) 0.3 0.4 1.1 0.9 -0.0 0.6 0.1 1.1 0.6 -0.6 -0.8
Average weekly beer plus cider intake 0.2 0.3 1.3 -1.1 0.3 -0.6 -0.3 0.5 -0.1 -0.0 -0.3
Irritability 0.1 0.2 1.1 -1.0 0.3 -0.0 -0.7 0.5 -0.1 0.1 -0.0
Risk taking 0.4 0.7 1.0 0.6 0.8 0.5 0.7 1.0 1.0 -0.8 -0.9
Ever had prostate specific antigen (PSA) test 0.2 0.3 1.0 0.1 -0.1 0.6 0.2 0.8 0.2 1.0 -0.2
Fractured/broken bones in last 5 years 2.7 3.5 6.8 -0.9 -1.6 -2.0 -2.1 -1.3 -2.3 2.6 1.6
Age started oral contraceptive pill 0.6 0.7 2.2 -0.9 -1.5 -0.7 -0.6 0.4 -1.1 0.3 0.8
Diastolic blood pressure, automated reading 0.9 2.7 10.4 1.6 3.2 2.1 1.2 0.8 1.2 -0.3 -0.6
Ever depressed for a whole week 0.8 0.9 1.2 1.1 -0.9 -0.9 -1.0 -0.9 -1.1 0.9 0.9
Unable to work because of sickness or disability 0.3 0.4 1.7 -0.0 1.0 0.3 0.1 1.3 0.5 -0.1 -0.3
Commuting to job workplace: Cycle 2.5 3.0 5.8 0.4 -2.4 -2.0 -1.7 0.1 -1.9 2.0 1.9
Myopia 0.5 0.7 2.2 -0.6 -1.5 -0.5 -0.9 -0.5 -0.9 -0.8 0.9
Vascular/heart problems diagnosed by doctor 1.2 3.3 15.0 -0.7 -3.9 -2.4 -1.1 -1.4 -1.4 0.1 0.1
Cholesterol lowering medication 0.6 0.8 3.3 -0.5 0.4 0.5 -0.7 -1.8 -0.6 0.8 1.1
Medication: Omeprazole (e.g. Zanprol) 1.7 2.0 4.1 -0.5 -1.1 -1.0 -2.0 -1.3 -1.6 1.5 1.8
Pain experienced in last month 0.1 0.2 0.8 0.9 -0.4 -0.3 0.0 0.2 -0.0 0.3 -0.0
Supplements: Calcium 0.2 0.3 1.6 0.4 -0.5 0.3 -0.3 -1.3 -0.2 0.0 -0.3
Basal cell carcinoma (self-reported) 0.6 0.8 1.9 1.1 -0.1 0.2 0.9 1.0 0.9 -1.4 -0.7
Heart attack/myocardial infarction (self-reported) 1.2 1.5 3.5 0.4 1.9 1.6 1.1 1.1 1.1 -1.3 -0.7
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 2.2 0.7 -0.9 -0.6 -1.5 -0.6 -1.1 0.7 1.0
Heart disease (siblings) 2.0 2.5 4.8 -2.2 -0.4 -2.1 -1.7 0.1 -1.6 1.7 1.4
Alcohol drinker status: Previous 1.1 1.2 3.0 0.9 1.4 1.0 1.0 1.7 0.9 -1.0 -0.5
Pack years of smoking 0.5 0.8 1.8 -0.3 -1.0 -1.1 -1.4 -0.5 -1.2 0.5 0.7
Impedance of whole body 1.2 6.0 20.2 1.3 4.5 3.5 2.4 1.1 2.3 -0.6 -1.2
Leg fat mass (left) 0.1 0.2 0.8 0.3 0.7 0.9 0.1 -0.4 0.4 -0.5 -0.2
Arm predicted mass (left) 0.1 0.7 2.8 -0.1 -1.7 -1.2 -0.6 -0.3 -0.2 -0.9 -0.3