TWAS hub - CSRNP1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.123	0.043	0.00032	0.022	NA	0.018	NA	0.024	0.0081	NA	0.016	NA	0.006
2	TCGA	Testicular Germ Cell Tumors	0.198	0.094	0.00220	0.058	0.035	0.015	NA	0.027	0.0041	0.022	0.094	NA	0.038

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Diverticular disease/diverticulitis (self-reported)	5.3	6.3	10.9	3.3	1.3
Lung cancer (father)	4.7	5.5	10.1	-3.2	-0.9
Hypothyroidism (self reported)	4.5	10.2	14.4	-3.8	-2.5
Prospective memory result	4.3	5.3	8.6	2.9	1.4
Alzheimer’s Disease (in father)	4.2	4.5	8.9	0.4	3.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.0	4.8	4.8	-2.2	-2.2
Ever highly irritable/argumentative for 2 days	3.8	4.5	7.2	1.4	2.7
Wheeze or whistling in the chest in last year	3.7	6.6	6.8	-2.6	-2.5
Mouth/teeth dental problems: Bleeding gums	3.6	4.7	6.6	-1.7	-2.6
Osteoporosis (self-reported)	3.6	4.4	8.5	2.9	0.5
Hair/balding pattern: Pattern 2	3.5	4.4	6.7	1.5	2.6
Hayfever/allergic rhinitis (self-reported)	3.5	4.6	7.0	-1.5	-2.6
Medication: Aspirin	3.5	4.6	8.3	-2.9	-0.9
Fractured/broken bones in last 5 years	3.4	4.4	4.8	2.0	2.2
Hypothyroidism/myxoedema (self-reported)	3.2	6.2	6.9	-2.6	-2.4
Asthma (self-reported)	3.2	6.3	7.1	-2.7	-2.3
Asthma	2.9	5.8	6.8	-2.6	-2.2
Severe depression (siblings)	2.8	3.1	3.2	1.8	1.8
Leg pain on walking	2.8	3.5	5.0	1.4	2.2
Ever unenthusiastic/disinterested for a whole week	2.7	3.3	6.2	0.5	2.5
Medication: Aspirin	2.7	3.6	6.1	-2.5	-1.0
Osteoarthritis (self-reported)	2.7	3.5	6.7	-0.5	2.6
Deep venous thrombosis (DVT) (self-reported)	2.7	3.5	6.2	0.9	2.5
Average weekly red wine intake	2.6	3.9	5.8	2.4	-1.4
Heel bone mineral density (BMD) T-score, automated (left)	2.5	5.6	9.3	-3.0	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	2.4	5.5	8.0	-2.8	-1.7
Hayfever, allergic rhinitis or eczema	2.3	5.0	8.4	-1.3	-2.9
Blood clot in the leg (DVT)	2.3	3.0	5.3	0.9	2.3
Medication: Blood pressure	2.3	4.1	6.0	-2.4	-1.5
Back pain experienced in last month	2.3	3.3	5.0	-1.3	2.2
Pain type(s) experienced in last month: Hip pain	2.3	2.9	4.2	-1.3	2.0
Lupus	2.2	3.3	4.8	-2.2	-1.3
Alzheimer’s Disease (including proxy)	2.1	3.1	5.7	0.7	2.4
Blood Platelet Count	2.1	24.8	46.8	-6.8	1.7
Respiratory disease	2.1	4.7	8.5	-2.9	-1.0
Hair/balding pattern: Pattern 4	1.9	4.7	7.1	-1.5	-2.7
Commuting to job workplace: Walk	1.9	2.1	4.1	2.0	0.1
Verbal and Numeric Reasoning (VNR)	1.8	4.3	5.4	-1.8	-2.3
Falls in the last year	1.8	2.5	3.6	1.2	1.9
Pulse rate	1.8	3.0	5.6	0.7	-2.4
Mean Putamen Volume	1.7	1.9	2.5	1.6	1.2
Hand grip strength (left)	1.7	4.5	8.6	0.5	-2.9
Number of treatments/medications taken	1.7	3.0	5.4	-2.3	-0.8
Hearing difficulty/problems with background noise	1.7	2.7	5.2	-2.3	0.4
Allergy	1.7	4.0	5.5	1.6	2.3
Fluid intelligence score	1.7	3.4	3.6	-1.9	-1.8
Qualifications: nursing, teaching	1.7	2.7	5.3	2.3	0.2
Guilty feelings	1.7	2.5	4.3	-0.9	2.1
Medication: Lisinopril	1.7	2.3	3.9	-0.8	-2.0
Illnesses of father: High blood pressure	1.7	2.1	3.0	-1.1	-1.7
Cholesterol lowering medication	1.7	2.4	4.7	0.4	2.2
Allergy or Eczema	1.6	4.1	6.4	-1.3	-2.5
Medication: Levothyroxine sodium	1.6	2.7	4.0	-2.0	-1.2
Alcohol usually taken with meals	1.6	2.6	5.1	0.2	-2.3
Illnesses of siblings	1.6	2.2	4.1	0.6	-2.0
Medication: Ibuprofen	1.6	2.0	3.1	-0.9	1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.9	3.7	-1.9	-0.3
Bipolar Disorder (2018)	1.5	2.3	4.4	-2.1	-0.4
Leg fat percentage (right)	1.5	5.6	8.2	-2.9	1.7
Average weekly beer plus cider intake	1.5	2.2	4.3	-0.0	2.1
Bipolar Disorder (2011)	1.4	1.4	2.5	-0.5	1.6
Hand grip strength (right)	1.4	3.9	7.8	0.0	-2.8
Breastfed as a baby	1.4	1.7	2.1	1.4	1.1
Glaucoma (self-reported)	1.4	1.6	3.0	-1.7	-0.5
Age at first live birth	1.4	2.6	2.9	1.7	-1.5
Knee pain experienced in last month	1.4	2.2	4.4	-0.2	-2.1
Eye problems/disorders: Glaucoma	1.4	1.7	3.3	-1.8	0.0
Number of operations (self-reported)	1.4	2.0	3.5	0.7	1.9
Happiness	1.3	1.6	2.8	0.6	1.7
Pulse wave reflection index	1.3	1.6	2.4	-0.9	1.6
Birth weight	1.3	2.8	4.3	2.1	1.1
Health satisfaction	1.3	1.7	3.1	-0.6	1.7
Chest pain or discomfort	1.3	1.8	3.7	-1.9	-0.0
Intelligence (Savage-Jansen 2018)	1.2	3.6	4.1	-2.0	-1.8
Schizophrenia vs Biploar Disorder	1.2	1.5	2.5	1.6	0.8
Crohns Disease (2017)	1.2	2.7	4.5	-0.9	2.1
Age at First Birth	1.2	1.7	2.2	1.5	1.1
Taking other prescription medications	1.2	1.8	1.9	-1.3	-1.4
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.6	-1.6	0.3
Serious illness, injury or assault to yourself	1.2	1.4	1.9	1.0	-1.4
Number of self-reported non-cancer illnesses	1.2	2.1	4.2	-2.1	-0.2
Impedance of leg (right)	1.1	5.5	10.9	-3.3	0.2
Had other major operations	1.1	1.4	2.2	0.7	1.5
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	3.4	1.9	0.5
Medication: Amlodipine	1.1	1.5	2.8	0.5	1.7
Exposure to tobacco smoke outside home	1.1	1.4	2.0	-0.9	-1.4
Shortness of breath walking on level ground	1.1	1.4	2.2	0.7	1.5
Qualifications: College or University degree	1.1	3.4	5.9	2.4	-0.9
Medication for pain relief, constipation, heartburn	1.1	2.0	3.9	2.0	-0.2
Suffer from ‘nerves’	1.1	1.7	1.8	-1.2	-1.4
Eye problems/disorders: Cataract	1.1	1.2	1.4	1.2	1.0
Leg fat percentage (left)	1.1	3.9	4.3	-2.1	1.9
Crohns Disease (2012)	1.0	1.6	3.1	-1.8	0.3
Triglycerides	1.0	1.6	3.0	-1.7	-0.4
Blood White Count	1.0	7.3	12.3	-3.5	-1.5
Heel T-Score	1.0	7.9	10.0	-3.2	-2.4
Age when periods started (menarche)	1.0	2.5	3.1	-1.8	-1.4
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	1.6	-1.3	0.8
Multivitamins +/- minerals	1.0	1.3	2.2	-0.6	-1.5
Stomach or abdominal pain in last month	1.0	1.2	1.8	1.3	-0.8
Eye problems/disorders: None of the above	1.0	1.2	2.4	0.2	-1.5
Loneliness, isolation	1.0	1.4	2.7	-1.6	0.1
High cholesterol (Self-reported)	1.0	1.8	3.6	0.1	1.9
Medication: Paracetamol	1.0	1.5	1.6	-1.2	1.3
Myopia	1.0	1.5	2.8	1.7	-0.3
Primary Biliary Cirrhosis	0.9	1.3	2.5	-1.6	0.1
Relative age voice broke	0.9	1.3	2.7	1.6	-0.2
Chronic bronchitis/emphysema (father)	0.9	1.0	2.0	-0.2	1.4
High blood pressure (mother)	0.9	1.3	2.6	-0.2	-1.6
Medication: Lansoprazole	0.9	1.0	2.0	-1.4	0.1
Headache pain in last month	0.9	1.6	2.2	-1.5	1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	1.9	0.2	1.4
Average weekly champagne plus white wine intake	0.9	1.3	2.2	1.5	0.6
Financial situation satisfaction	0.9	1.1	1.7	0.7	1.3
Lung FEV1/FVC ratio	0.8	4.1	6.5	2.5	-1.3
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.7	-0.3	1.3
Angina	0.8	1.0	1.2	1.1	0.9
Medication: Simvastatin	0.8	1.2	2.3	-0.1	1.5
Time employed in main current job	0.8	0.9	1.2	-0.7	-1.1
Worrier / anxious feelings	0.8	1.6	3.1	0.3	1.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.7	2.8	1.6	-1.7
Medication: Omeprazole	0.8	1.0	1.9	-0.3	1.4
Leg fat mass (right)	0.8	3.0	4.7	-2.2	1.1
Age at last live birth	0.8	1.1	2.1	1.5	-0.2
Basal cell carcinoma (self-reported)	0.8	1.0	1.5	-0.7	-1.2
LDL Cholesterol	0.7	1.0	1.3	1.1	0.9
Cardiovascular Disease	0.7	2.5	3.7	-1.9	-1.1
Average weekly spirits intake	0.7	0.9	1.2	1.1	0.7
Other serious medical condition/disability diagnosed by doctor	0.7	1.0	1.4	0.7	-1.2
Ever used hormone-replacement therapy (HRT)	0.7	0.8	1.5	-0.4	1.2
Ever had hysterectomy (womb removed)	0.7	0.7	1.5	0.2	1.2
Medication: Metformin	0.7	0.9	1.8	-1.4	0.2
Diabetes (father)	0.7	0.8	1.3	-0.6	-1.1
Impedance of leg (left)	0.7	3.4	6.8	-2.6	0.3
Qualifications: None of the above	0.7	1.4	1.6	-1.2	1.1
Pain all over the body in last month	0.7	0.8	1.0	0.7	1.0
Qualifications: A levels/AS levels or equivalent	0.7	1.5	2.3	1.5	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.0	-1.0	0.9
Loud music exposure frequency	0.7	0.7	1.5	1.2	-0.1
Qualifications: O levels/GCSEs or equivalent	0.7	1.2	1.9	1.4	-0.6
Body fat percentage	0.7	2.8	3.9	-2.0	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	1.7	-0.3	-1.3
Neck or shoulder pain in last month	0.7	1.0	1.5	0.7	1.2
Alcohol intake frequency.	0.7	1.6	2.9	-1.7	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	2.6	-0.5	-1.6
Friendships satisfaction	0.7	0.9	0.9	-0.9	0.9
Ever depressed for a whole week	0.7	0.8	1.6	-0.3	1.3
Vascular/heart problems diagnosed by doctor	0.7	1.8	3.5	1.9	0.2
Reaction Time	0.6	1.2	1.8	1.3	-0.7
Prostate Cancer	0.6	0.8	0.9	-0.9	-1.0
Fasting Glucose	0.6	0.7	1.0	1.0	0.7
Rheumatoid Arthritis	0.6	0.8	1.3	1.1	-0.6
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.4	0.3	-1.2
Smoking Status	0.6	1.4	2.8	-0.1	1.7
Chronotype (morning person)	0.6	1.4	2.9	1.7	-0.1
High blood pressure	0.6	1.8	3.4	-1.9	-0.4
Nervous feelings	0.6	1.1	2.0	-1.4	0.5
Alcohol intake versus 10 years previously	0.6	1.0	1.5	-1.2	-0.7
Number of live births	0.6	0.9	0.9	-0.9	1.0
Forced expiratory volume in 1-second (FEV1)	0.6	2.2	2.6	1.6	-1.3
Exposure to tobacco smoke at home	0.6	0.7	1.1	-0.6	1.1
Angina (self-reported)	0.6	0.8	0.9	0.9	0.8
Mean time to correctly identify matches	0.6	1.2	1.8	1.3	-0.8
Supplements: Vitamin C	0.6	0.7	1.2	0.5	-1.1
Smoking status: Current	0.6	0.9	1.9	0.0	1.4
Tinnitus: Yes, now most or all of the time	0.6	0.8	1.2	1.1	0.6
Medication: Bendroflumethiazide	0.6	0.9	1.8	-1.3	-0.2
Pain experienced in last month	0.6	1.0	1.8	1.3	-0.4
Alcohol drinker status: Previous	0.6	0.7	1.2	-1.1	-0.4
Leg fat mass (left)	0.6	2.2	3.1	-1.8	1.1
HbA1C	0.5	0.5	0.8	0.9	-0.5
Schizophrenia (2014)	0.5	1.1	1.6	-0.8	1.3
Ulcerative Colitis	0.5	0.7	1.3	0.4	-1.1
Lung FVC	0.5	2.7	4.5	2.1	-1.0
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.3	-0.1	-1.1
Diabetes (mother)	0.5	0.7	1.0	-0.6	1.0
Trunk fat percentage	0.5	1.9	2.6	-1.6	1.1
Current tobacco smoking	0.5	0.8	1.5	-0.2	1.2
Medication: Atenolol	0.5	0.6	0.9	-0.9	-0.5
Had menopause	0.5	0.6	1.0	-1.0	0.4
Arm fat percentage (right)	0.5	1.8	2.5	-1.6	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.0	-1.0	-0.2
Medication: Cholesterol lowering	0.5	0.8	1.0	-1.0	0.7
Chronic bronchitis/emphysema (mother)	0.5	0.6	0.8	0.6	0.9
Emphysema/chronic bronchitis	0.5	0.5	0.7	-0.6	-0.8
Whole body fat mass	0.5	1.9	2.7	-1.6	1.1
Family relationship satisfaction	0.5	0.6	1.0	-1.0	0.5
Smoking status: Previous	0.5	0.8	1.5	-1.2	0.1
Hearing aid user	0.5	0.6	1.2	-0.0	1.1
Commuting to job workplace: Public transport	0.5	0.6	1.2	-0.3	-1.1
Irritability	0.5	0.8	0.8	0.9	0.9
Ever had prostate specific antigen (PSA) test	0.5	0.5	0.8	0.5	-0.9
Heart disease (siblings)	0.5	0.6	1.1	-1.1	0.2
Pack years of smoking	0.5	0.7	1.3	1.2	0.4
Neuroticism (Nagel 2018)	0.4	1.0	1.7	-0.5	1.3
Breast Cancer	0.4	1.0	2.0	0.1	-1.4
Ovarian Cancer	0.4	0.6	1.1	0.1	-1.1
Neuroticism (2016)	0.4	0.6	1.0	-1.0	-0.4
Neuroticism	0.4	1.0	1.8	0.5	1.3
Pack years adult smoking proportion	0.4	0.6	1.2	1.1	0.2
Fed-up feelings	0.4	0.7	0.7	0.8	0.9
Trunk fat mass	0.4	1.5	2.2	-1.5	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	0.8	0.6	0.9
Financial difficulties in last 2 years	0.4	0.5	1.0	-0.0	1.0
Mouth/teeth dental problems	0.4	0.6	0.7	0.6	0.9
Heart attack	0.4	0.5	0.9	-1.0	-0.2
Neuroticism score	0.4	0.9	1.0	0.9	1.0
Impedance of arm (right)	0.4	2.0	3.6	-1.9	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	0.7	0.8	0.7
Hair/balding pattern: Pattern 3	0.4	0.6	1.1	-1.1	0.1
Birth weight of first child	0.4	0.7	0.8	0.8	0.9
Worry too long after embarrassment	0.4	0.7	1.3	-1.1	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	0.6	0.6	-0.7
Medication: Allopurinol	0.4	0.6	0.7	0.9	0.6
Medication: Seretide 50 evohaler	0.4	0.5	1.0	-1.0	-0.2
Number of full sisters	0.4	0.4	0.5	-0.6	0.7
Overall health rating	0.4	0.9	1.7	0.2	1.3
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.9	-1.0	0.2
Hypertension (Self-reported)	0.4	1.2	2.5	-1.6	0.0
Arm fat percentage (left)	0.4	1.8	2.5	-1.6	1.0
Medication: Gliclazide	0.4	0.5	0.5	-0.7	0.7
Wears glasses or contact lenses	0.4	0.5	0.5	0.7	-0.7
Unable to work because of sickness or disability	0.4	0.5	1.0	1.0	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	0.8	-0.5	0.9
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.9	-1.0	-0.3
Impedance of whole body	0.4	2.2	4.3	-2.1	-0.3
Schizophrenia (2018)	0.3	0.7	1.1	0.5	1.1
Irritable Bowel Disease (IBD)	0.3	0.7	1.4	-0.1	1.2
Blood Red Count	0.3	2.9	3.0	-1.7	1.7
Waist Hip Ratio (WHR)	0.3	1.5	1.8	-1.4	1.1
Sensitivity / hurt feelings	0.3	0.5	1.0	0.1	1.0
Medication for hormone replacement therapy	0.3	0.3	0.4	0.4	-0.7
Vitamin and mineral supplements	0.3	0.3	0.6	-0.3	0.8
Medication: Co-codamol	0.3	0.3	0.5	-0.4	0.7
Average weekly fortified wine intake	0.3	0.4	0.5	-0.6	-0.7
Maternal smoking around birth	0.3	0.4	0.8	0.0	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	0.8	0.9	-0.3
Supplements: Glucosamine	0.3	0.4	0.9	0.0	-0.9
Sitting height	0.3	2.3	4.6	-0.1	-2.2
Waist circumference	0.3	1.1	1.4	-0.9	1.2
Father’s age at death	0.3	0.4	0.4	-0.6	-0.6
Mouth/teeth dental problems: Dentures	0.3	0.5	1.0	-1.0	-0.3
Impedance of arm (left)	0.3	1.2	2.2	-1.5	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.5	-0.6	0.7
Number of children fathered	0.3	0.3	0.6	-0.7	-0.1
Pulse rate, automated reading	0.3	0.9	1.8	-0.1	-1.3
Leg fat-free mass (right)	0.3	1.5	2.7	1.6	-0.5
Leg predicted mass (right)	0.3	1.4	2.7	1.6	-0.5
Arm fat mass (left)	0.3	1.0	1.1	-1.0	1.0
Ever taken oral contraceptive pill	0.3	0.3	0.5	0.4	0.7
Mother’s age at death	0.3	0.4	0.8	0.9	-0.3
Age started oral contraceptive pill	0.3	0.4	0.8	-0.9	0.0
Supplements: Calcium	0.3	0.4	0.7	0.2	0.8
Bipolar Disorder or Schizophrenia	0.2	0.6	0.9	-0.9	0.6
Body Mass Index (BMI) (2010)	0.2	0.2	0.4	-0.0	-0.7
HDL Cholesterol	0.2	0.4	0.8	0.9	0.1
Qualifications: CSEs or equivalent	0.2	0.3	0.3	-0.6	0.4
Body mass index (BMI)	0.2	0.9	1.7	-0.3	1.3
Past tobacco smoking	0.2	0.3	0.5	0.7	-0.4
Forced vital capacity (FVC)	0.2	0.7	1.0	1.0	-0.6
Medication: Ramipril	0.2	0.3	0.3	0.6	-0.5
Noisy workplace	0.2	0.2	0.2	0.5	0.4
Arm fat mass (right)	0.2	1.0	1.0	-1.0	1.0
Length of working week for main job	0.2	0.2	0.4	-0.1	-0.6
Tense / ‘highly strung’	0.2	0.3	0.6	0.8	0.1
Medication: Paracetamol	0.2	0.3	0.6	-0.8	0.1
High blood pressure (siblings)	0.2	0.3	0.4	0.5	0.6
Forced vital capacity (FVC), Best measure	0.2	0.8	0.9	0.9	-0.9
Comparative body size at age 10	0.2	0.5	1.0	1.0	0.0
Arm predicted mass (right)	0.2	0.9	1.6	1.3	0.4
Had major operations	0.2	0.2	0.4	-0.6	0.0
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.3	-0.3	0.6
Illnesses of father: Heart disease	0.2	0.3	0.4	0.6	0.3
Mood swings	0.2	0.3	0.4	0.7	-0.3
Long-standing illness, disability or infirmity	0.2	0.3	0.4	-0.3	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.6	-0.3	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.3	-0.4	-0.5
Breast cancer (self-reported)	0.2	0.2	0.4	-0.6	0.1
Whole body water mass	0.2	0.9	1.8	1.3	-0.1
Medication: Atorvastatin	0.2	0.2	0.4	0.6	0.3
Ever smoked	0.2	0.4	0.5	-0.7	0.5
Depressed Affect (Nagel 2018)	0.1	0.3	0.5	-0.2	0.7
Depression (Nagel 2018)	0.1	0.1	0.2	-0.3	-0.4
Worry (Nagel 2018)	0.1	0.2	0.4	-0.3	0.6
Alzheimer’s Disease (in mother)	0.1	0.1	0.3	-0.2	0.5
Major Depression (MDD)	0.1	0.1	0.2	-0.4	0.3
Blood Eosinophil Count	0.1	0.4	0.8	-0.9	-0.4
Height	0.1	2.8	5.7	0.2	-2.4
Type 2 Diabetes (T2D) (2018)	0.1	0.3	0.5	-0.7	0.2
Tanning	0.1	0.8	1.3	-0.6	-1.1
Hearing difficulty/problems: Yes	0.1	0.2	0.3	0.6	-0.2
Relative age of first facial hair	0.1	0.1	0.2	0.0	0.5
Systolic blood pressure, automated reading	0.1	0.2	0.4	0.1	0.6
Leg fat-free mass (left)	0.1	0.6	1.1	1.0	-0.4
Townsend deprivation index at recruitment	0.1	0.1	0.2	0.4	-0.3
Leg predicted mass (left)	0.1	0.6	1.0	1.0	-0.4
Number of incorrect matches in round	0.1	0.2	0.2	0.3	-0.5
Diabetes (self-reported)	0.1	0.2	0.4	-0.6	-0.0
Weight	0.1	0.3	0.6	-0.2	0.8
Trunk fat-free mass	0.1	0.6	1.1	1.1	0.0
Trunk predicted mass	0.1	0.5	0.9	1.0	0.0
Standing height	0.1	0.7	1.3	0.1	-1.1
Peak expiratory flow (PEF)	0.1	0.1	0.2	0.2	-0.5
Gout (self-reported)	0.1	0.2	0.2	0.5	-0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.2	0.3	0.4
Arm fat-free mass (right)	0.1	0.6	1.1	1.1	0.3
Number of full brothers	0.1	0.1	0.2	0.1	-0.4
Pulse wave peak to peak time	0.1	0.1	0.1	0.3	-0.3
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	-0.2	-0.3
Heart disease (mother)	0.1	0.2	0.3	-0.6	0.0
Comparative height size at age 10	0.1	0.5	0.6	-0.8	0.6
Illnesses of siblings: Diabetes	0.1	0.2	0.3	-0.3	0.5
Whole body fat-free mass	0.1	0.8	1.6	1.2	-0.2
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.3	0.3	-0.5
Medication for cholesterol	0.1	0.2	0.4	-0.6	0.0
Mineral and other dietary supplements	0.1	0.1	0.1	0.3	0.2
Illnesses of father: None of the above (group 1)	0.1	0.1	0.3	0.2	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.6	-0.1	-0.8
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.2	0.5	0.3
Alcohol drinker status: Never	0.1	0.1	0.1	0.4	0.3
Basal metabolic rate	0.1	0.4	0.8	0.9	-0.0
Arm fat-free mass (left)	0.1	0.5	0.8	0.9	0.3
Commuting to job workplace: Cycle	0.1	0.1	0.2	0.0	-0.5
Arm predicted mass (left)	0.1	0.5	1.0	1.0	0.3
Ulcerative Colitis (UC)	0.0	0.0	0.0	0.1	-0.1
Coronary Artery Disease (CAD)	0.0	0.1	0.1	0.3	0.2
BMI	0.0	0.2	0.2	0.5	0.4
Systolic Blood Pressure	0.0	0.2	0.4	0.6	-0.2
Hair Pigment	0.0	0.5	0.6	-0.6	-0.8
Supplements: Zinc	0.0	0.0	0.1	0.2	-0.3
Hip circumference	0.0	0.2	0.2	-0.4	0.4
Depression (self-reported)	0.0	0.0	0.1	-0.2	-0.2
Illnesses of mother	0.0	0.1	0.1	-0.2	-0.3
Pulse wave Arterial Stiffness index	0.0	0.0	0.1	-0.3	0.0
Migraine (self-reported)	0.0	0.0	0.0	0.1	-0.0
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	-0.1	0.2
Ever had bowel cancer screening	0.0	0.0	0.0	0.1	-0.2
Diabetes diagnosed by doctor	0.0	0.0	0.1	-0.1	0.3
Miserableness	0.0	0.1	0.1	0.1	0.3
Medication: Blood pressure	0.0	0.0	0.1	0.1	0.3
Risk taking	0.0	0.0	0.0	0.1	0.2
Diastolic blood pressure, automated reading	0.0	0.0	0.1	-0.3	-0.1

Hub : Genes

CSRNP1

Models

Trait associations