Hub : Genes

CSRNP1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Cells Transformed fibroblasts 0.123 0.043 0.00032 0.022 NA 0.018 NA 0.024 0.0081 NA 0.016 NA 0.006
2 TCGA Testicular Germ Cell Tumors 0.198 0.094 0.00220 0.058 0.035 0.015 NA 0.027 0.0041 0.022 0.094 NA 0.038

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 1.5 2.3 4.4 -2.1 -0.4
Bipolar Disorder or Schizophrenia 0.2 0.6 0.9 -0.9 0.6
Depressed Affect (Nagel 2018) 0.1 0.3 0.5 -0.2 0.7
Depression (Nagel 2018) 0.1 0.1 0.2 -0.3 -0.4
Intelligence (Savage-Jansen 2018) 1.2 3.6 4.1 -2.0 -1.8
Neuroticism (Nagel 2018) 0.4 1.0 1.7 -0.5 1.3
Schizophrenia (2018) 0.3 0.7 1.1 0.5 1.1
Schizophrenia vs Biploar Disorder 1.2 1.5 2.5 1.6 0.8
Worry (Nagel 2018) 0.1 0.2 0.4 -0.3 0.6
Alzheimer’s Disease (in mother) 0.1 0.1 0.3 -0.2 0.5
Alzheimer’s Disease (in father) 4.2 4.5 8.9 0.4 3.0
Alzheimer’s Disease (including proxy) 2.1 3.1 5.7 0.7 2.4
Crohns Disease (2017) 1.2 2.7 4.5 -0.9 2.1
Irritable Bowel Disease (IBD) 0.3 0.7 1.4 -0.1 1.2
Ulcerative Colitis (UC) 0.0 0.0 0.0 0.1 -0.1
Major Depression (MDD) 0.1 0.1 0.2 -0.4 0.3
Reaction Time 0.6 1.2 1.8 1.3 -0.7
Verbal and Numeric Reasoning (VNR) 1.8 4.3 5.4 -1.8 -2.3
Breast Cancer 0.4 1.0 2.0 0.1 -1.4
Ovarian Cancer 0.4 0.6 1.1 0.1 -1.1
Prostate Cancer 0.6 0.8 0.9 -0.9 -1.0
Age at First Birth 1.2 1.7 2.2 1.5 1.1
Bipolar Disorder (2011) 1.4 1.4 2.5 -0.5 1.6
Body Mass Index (BMI) (2010) 0.2 0.2 0.4 -0.0 -0.7
Coronary Artery Disease (CAD) 0.0 0.1 0.1 0.3 0.2
Crohns Disease (2012) 1.0 1.6 3.1 -1.8 0.3
Mean Putamen Volume 1.7 1.9 2.5 1.6 1.2
Fasting Glucose 0.6 0.7 1.0 1.0 0.7
HbA1C 0.5 0.5 0.8 0.9 -0.5
HDL Cholesterol 0.2 0.4 0.8 0.9 0.1
LDL Cholesterol 0.7 1.0 1.3 1.1 0.9
Lupus 2.2 3.3 4.8 -2.2 -1.3
Neuroticism (2016) 0.4 0.6 1.0 -1.0 -0.4
Primary Biliary Cirrhosis 0.9 1.3 2.5 -1.6 0.1
Rheumatoid Arthritis 0.6 0.8 1.3 1.1 -0.6
Schizophrenia (2014) 0.5 1.1 1.6 -0.8 1.3
Triglycerides 1.0 1.6 3.0 -1.7 -0.4
Type 2 Diabetes (T2D) (2012) 0.6 0.7 1.4 0.3 -1.2
Ulcerative Colitis 0.5 0.7 1.3 0.4 -1.1
Blood Eosinophil Count 0.1 0.4 0.8 -0.9 -0.4
Blood Platelet Count 2.1 24.8 46.8 -6.8 1.7
Blood Red Count 0.3 2.9 3.0 -1.7 1.7
Blood White Count 1.0 7.3 12.3 -3.5 -1.5
Heel T-Score 1.0 7.9 10.0 -3.2 -2.4
BMI 0.0 0.2 0.2 0.5 0.4
Height 0.1 2.8 5.7 0.2 -2.4
Waist Hip Ratio (WHR) 0.3 1.5 1.8 -1.4 1.1
Systolic Blood Pressure 0.0 0.2 0.4 0.6 -0.2
Smoking Status 0.6 1.4 2.8 -0.1 1.7
Allergy or Eczema 1.6 4.1 6.4 -1.3 -2.5
Cardiovascular Disease 0.7 2.5 3.7 -1.9 -1.1
Hypothyroidism (self reported) 4.5 10.2 14.4 -3.8 -2.5
Respiratory disease 2.1 4.7 8.5 -2.9 -1.0
Type 2 Diabetes (T2D) (2018) 0.1 0.3 0.5 -0.7 0.2
Lung FEV1/FVC ratio 0.8 4.1 6.5 2.5 -1.3
Lung FVC 0.5 2.7 4.5 2.1 -1.0
Neuroticism 0.4 1.0 1.8 0.5 1.3
Chronotype (morning person) 0.6 1.4 2.9 1.7 -0.1
Hair Pigment 0.0 0.5 0.6 -0.6 -0.8
Tanning 0.1 0.8 1.3 -0.6 -1.1
Hand grip strength (left) 1.7 4.5 8.6 0.5 -2.9
Number of treatments/medications taken 1.7 3.0 5.4 -2.3 -0.8
Average weekly spirits intake 0.7 0.9 1.2 1.1 0.7
Sensitivity / hurt feelings 0.3 0.5 1.0 0.1 1.0
Frequency of depressed mood in last 2 weeks 0.5 0.7 1.3 -0.1 -1.1
Hearing difficulty/problems: Yes 0.1 0.2 0.3 0.6 -0.2
Relative age of first facial hair 0.1 0.1 0.2 0.0 0.5
Other serious medical condition/disability diagnosed by doctor 0.7 1.0 1.4 0.7 -1.2
Ever used hormone-replacement therapy (HRT) 0.7 0.8 1.5 -0.4 1.2
Ever had hysterectomy (womb removed) 0.7 0.7 1.5 0.2 1.2
Systolic blood pressure, automated reading 0.1 0.2 0.4 0.1 0.6
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 1.7 -0.3 1.3
Angina 0.8 1.0 1.2 1.1 0.9
Medication for hormone replacement therapy 0.3 0.3 0.4 0.4 -0.7
Vitamin and mineral supplements 0.3 0.3 0.6 -0.3 0.8
Supplements: Zinc 0.0 0.0 0.1 0.2 -0.3
Medication: Co-codamol 0.3 0.3 0.5 -0.4 0.7
Medication: Metformin 0.7 0.9 1.8 -1.4 0.2
Diabetes (father) 0.7 0.8 1.3 -0.6 -1.1
Diabetes (mother) 0.5 0.7 1.0 -0.6 1.0
Severe depression (siblings) 2.8 3.1 3.2 1.8 1.8
Pack years adult smoking proportion 0.4 0.6 1.2 1.1 0.2
Impedance of leg (right) 1.1 5.5 10.9 -3.3 0.2
Leg fat-free mass (left) 0.1 0.6 1.1 1.0 -0.4
Trunk fat percentage 0.5 1.9 2.6 -1.6 1.1
Hand grip strength (right) 1.4 3.9 7.8 0.0 -2.8
Townsend deprivation index at recruitment 0.1 0.1 0.2 0.4 -0.3
Current tobacco smoking 0.5 0.8 1.5 -0.2 1.2
Average weekly fortified wine intake 0.3 0.4 0.5 -0.6 -0.7
Maternal smoking around birth 0.3 0.4 0.8 0.0 0.9
Fed-up feelings 0.4 0.7 0.7 0.8 0.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.5 0.8 0.9 -0.3
Relative age voice broke 0.9 1.3 2.7 1.6 -0.2
Taking other prescription medications 1.2 1.8 1.9 -1.3 -1.4
Age when periods started (menarche) 1.0 2.5 3.1 -1.8 -1.4
Bilateral oophorectomy (both ovaries removed) 1.2 1.4 2.6 -1.6 0.3
Heel bone mineral density (BMD) T-score, automated (left) 2.5 5.6 9.3 -3.0 -1.4
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 1.6 -1.3 0.8
Qualifications: CSEs or equivalent 0.2 0.3 0.3 -0.6 0.4
Serious illness, injury or assault to yourself 1.2 1.4 1.9 1.0 -1.4
High blood pressure 0.6 1.8 3.4 -1.9 -0.4
Hayfever, allergic rhinitis or eczema 2.3 5.0 8.4 -1.3 -2.9
Multivitamins +/- minerals 1.0 1.3 2.2 -0.6 -1.5
Stomach or abdominal pain in last month 1.0 1.2 1.8 1.3 -0.8
Supplements: Glucosamine 0.3 0.4 0.9 0.0 -0.9
Diverticular disease/diverticulitis (self-reported) 5.3 6.3 10.9 3.3 1.3
Medication: Atenolol 0.5 0.6 0.9 -0.9 -0.5
Medication: Levothyroxine sodium 1.6 2.7 4.0 -2.0 -1.2
Sitting height 0.3 2.3 4.6 -0.1 -2.2
Chronic bronchitis/emphysema (father) 0.9 1.0 2.0 -0.2 1.4
High blood pressure (mother) 0.9 1.3 2.6 -0.2 -1.6
Body mass index (BMI) 0.2 0.9 1.7 -0.3 1.3
Impedance of leg (left) 0.7 3.4 6.8 -2.6 0.3
Leg predicted mass (left) 0.1 0.6 1.0 1.0 -0.4
Trunk fat mass 0.4 1.5 2.2 -1.5 1.0
Waist circumference 0.3 1.1 1.4 -0.9 1.2
Number of incorrect matches in round 0.1 0.2 0.2 0.3 -0.5
Past tobacco smoking 0.2 0.3 0.5 0.7 -0.4
Alcohol usually taken with meals 1.6 2.6 5.1 0.2 -2.3
Nervous feelings 0.6 1.1 2.0 -1.4 0.5
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 0.8 0.6 0.9
Hearing difficulty/problems with background noise 1.7 2.7 5.2 -2.3 0.4
Hair/balding pattern: Pattern 2 3.5 4.4 6.7 1.5 2.6
Had menopause 0.5 0.6 1.0 -1.0 0.4
Had other major operations 1.1 1.4 2.2 0.7 1.5
Forced vital capacity (FVC) 0.2 0.7 1.0 1.0 -0.6
Heel bone mineral density (BMD) T-score, automated (right) 2.4 5.5 8.0 -2.8 -1.7
Ever unenthusiastic/disinterested for a whole week 2.7 3.3 6.2 0.5 2.5
Qualifications: None of the above 0.7 1.4 1.6 -1.2 1.1
Financial difficulties in last 2 years 0.4 0.5 1.0 -0.0 1.0
Mouth/teeth dental problems 0.4 0.6 0.7 0.6 0.9
Heart attack 0.4 0.5 0.9 -1.0 -0.2
Allergy 1.7 4.0 5.5 1.6 2.3
Pain all over the body in last month 0.7 0.8 1.0 0.7 1.0
Diabetes (self-reported) 0.1 0.2 0.4 -0.6 -0.0
Hayfever/allergic rhinitis (self-reported) 3.5 4.6 7.0 -1.5 -2.6
Medication: Ramipril 0.2 0.3 0.3 0.6 -0.5
Medication: Simvastatin 0.8 1.2 2.3 -0.1 1.5
Fluid intelligence score 1.7 3.4 3.6 -1.9 -1.8
Illnesses of siblings 1.6 2.2 4.1 0.6 -2.0
Neuroticism score 0.4 0.9 1.0 0.9 1.0
Weight 0.1 0.3 0.6 -0.2 0.8
Impedance of arm (right) 0.4 2.0 3.6 -1.9 -0.6
Arm fat percentage (right) 0.5 1.8 2.5 -1.6 1.0
Trunk fat-free mass 0.1 0.6 1.1 1.1 0.0
Hip circumference 0.0 0.2 0.2 -0.4 0.4
Time employed in main current job 0.8 0.9 1.2 -0.7 -1.1
Alcohol intake versus 10 years previously 0.6 1.0 1.5 -1.2 -0.7
Father’s age at death 0.3 0.4 0.4 -0.6 -0.6
Worrier / anxious feelings 0.8 1.6 3.1 0.3 1.8
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 0.7 0.8 0.7
Falls in the last year 1.8 2.5 3.6 1.2 1.9
Hair/balding pattern: Pattern 3 0.4 0.6 1.1 -1.1 0.1
Number of live births 0.6 0.9 0.9 -0.9 1.0
Forced expiratory volume in 1-second (FEV1) 0.6 2.2 2.6 1.6 -1.3
Pulse rate 1.8 3.0 5.6 0.7 -2.4
Happiness 1.3 1.6 2.8 0.6 1.7
Noisy workplace 0.2 0.2 0.2 0.5 0.4
Qualifications: A levels/AS levels or equivalent 0.7 1.5 2.3 1.5 -0.9
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.5 1.0 -1.0 -0.2
Mouth/teeth dental problems: Dentures 0.3 0.5 1.0 -1.0 -0.3
Asthma 2.9 5.8 6.8 -2.6 -2.2
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 1.0 -1.0 0.9
Medication: Cholesterol lowering 0.5 0.8 1.0 -1.0 0.7
Depression (self-reported) 0.0 0.0 0.1 -0.2 -0.2
Medication: Lansoprazole 0.9 1.0 2.0 -1.4 0.1
Prospective memory result 4.3 5.3 8.6 2.9 1.4
Lung cancer (father) 4.7 5.5 10.1 -3.2 -0.9
Illnesses of mother 0.0 0.1 0.1 -0.2 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.7 2.8 1.6 -1.7
Pulse wave Arterial Stiffness index 0.0 0.0 0.1 -0.3 0.0
Impedance of arm (left) 0.3 1.2 2.2 -1.5 -0.5
Arm fat mass (right) 0.2 1.0 1.0 -1.0 1.0
Trunk predicted mass 0.1 0.5 0.9 1.0 0.0
Standing height 0.1 0.7 1.3 0.1 -1.1
Length of working week for main job 0.2 0.2 0.4 -0.1 -0.6
Exposure to tobacco smoke at home 0.6 0.7 1.1 -0.6 1.1
Breastfed as a baby 1.4 1.7 2.1 1.4 1.1
Tense / ‘highly strung’ 0.2 0.3 0.6 0.8 0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 0.5 -0.6 0.7
Hair/balding pattern: Pattern 4 1.9 4.7 7.1 -1.5 -2.7
Birth weight of first child 0.4 0.7 0.8 0.8 0.9
Peak expiratory flow (PEF) 0.1 0.1 0.2 0.2 -0.5
Pulse wave reflection index 1.3 1.6 2.4 -0.9 1.6
Ever highly irritable/argumentative for 2 days 3.8 4.5 7.2 1.4 2.7
Loud music exposure frequency 0.7 0.7 1.5 1.2 -0.1
Qualifications: O levels/GCSEs or equivalent 0.7 1.2 1.9 1.4 -0.6
Mouth/teeth dental problems: Bleeding gums 3.6 4.7 6.6 -1.7 -2.6
Blood clot in the leg (DVT) 2.3 3.0 5.3 0.9 2.3
Medication: Paracetamol 0.2 0.3 0.6 -0.8 0.1
Headache pain in last month 0.9 1.6 2.2 -1.5 1.0
Medication for cholesterol, blood pressure or diabetes 1.1 1.8 3.4 1.9 0.5
Glaucoma (self-reported) 1.4 1.6 3.0 -1.7 -0.5
Gout (self-reported) 0.1 0.2 0.2 0.5 -0.3
Hypothyroidism/myxoedema (self-reported) 3.2 6.2 6.9 -2.6 -2.4
Medication: Amlodipine 1.1 1.5 2.8 0.5 1.7
Medication: Ventolin 100micrograms inhaler 0.1 0.1 0.2 0.3 0.4
Birth weight 1.3 2.8 4.3 2.1 1.1
Chronic bronchitis/emphysema (mother) 0.5 0.6 0.8 0.6 0.9
High blood pressure (siblings) 0.2 0.3 0.4 0.5 0.6
Forced vital capacity (FVC), Best measure 0.2 0.8 0.9 0.9 -0.9
Body fat percentage 0.7 2.8 3.9 -2.0 1.3
Leg fat percentage (right) 1.5 5.6 8.2 -2.9 1.7
Arm fat-free mass (right) 0.1 0.6 1.1 1.1 0.3
Exposure to tobacco smoke outside home 1.1 1.4 2.0 -0.9 -1.4
Comparative body size at age 10 0.2 0.5 1.0 1.0 0.0
Number of full brothers 0.1 0.1 0.2 0.1 -0.4
Worry too long after embarrassment 0.4 0.7 1.3 -1.1 0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 0.9 1.7 -0.3 -1.3
Wheeze or whistling in the chest in last year 3.7 6.6 6.8 -2.6 -2.5
Number of children fathered 0.3 0.3 0.6 -0.7 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.4 0.6 0.6 -0.7
Age at first live birth 1.4 2.6 2.9 1.7 -1.5
Pulse wave peak to peak time 0.1 0.1 0.1 0.3 -0.3
Health satisfaction 1.3 1.7 3.1 -0.6 1.7
Shortness of breath walking on level ground 1.1 1.4 2.2 0.7 1.5
Qualifications: College or University degree 1.1 3.4 5.9 2.4 -0.9
Eye problems/disorders: None of the above 1.0 1.2 2.4 0.2 -1.5
Mouth/teeth dental problems: Loose teeth 0.1 0.1 0.1 -0.2 -0.3
Emphysema/chronic bronchitis 0.5 0.5 0.7 -0.6 -0.8
Medication for pain relief, constipation, heartburn 1.1 2.0 3.9 2.0 -0.2
Neck or shoulder pain in last month 0.7 1.0 1.5 0.7 1.2
Medication: Blood pressure 2.3 4.1 6.0 -2.4 -1.5
Angina (self-reported) 0.6 0.8 0.9 0.9 0.8
Migraine (self-reported) 0.0 0.0 0.0 0.1 -0.0
Medication: Ibuprofen 1.6 2.0 3.1 -0.9 1.8
Medication: Allopurinol 0.4 0.6 0.7 0.9 0.6
Medication: Omeprazole 0.8 1.0 1.9 -0.3 1.4
Medication: Seretide 50 evohaler 0.4 0.5 1.0 -1.0 -0.2
Mean time to correctly identify matches 0.6 1.2 1.8 1.3 -0.8
Heart disease (mother) 0.1 0.2 0.3 -0.6 0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 4.0 4.8 4.8 -2.2 -2.2
Whole body fat mass 0.5 1.9 2.7 -1.6 1.1
Leg fat mass (right) 0.8 3.0 4.7 -2.2 1.1
Arm predicted mass (right) 0.2 0.9 1.6 1.3 0.4
Pulse rate, automated reading 0.3 0.9 1.8 -0.1 -1.3
Alcohol intake frequency. 0.7 1.6 2.9 -1.7 -0.6
Comparative height size at age 10 0.1 0.5 0.6 -0.8 0.6
Number of full sisters 0.4 0.4 0.5 -0.6 0.7
Suffer from ‘nerves’ 1.1 1.7 1.8 -1.2 -1.4
Overall health rating 0.4 0.9 1.7 0.2 1.3
Chest pain or discomfort 1.3 1.8 3.7 -1.9 -0.0
Had major operations 0.2 0.2 0.4 -0.6 0.0
Age at last live birth 0.8 1.1 2.1 1.5 -0.2
Family relationship satisfaction 0.5 0.6 1.0 -1.0 0.5
Leg pain on walking 2.8 3.5 5.0 1.4 2.2
Qualifications: NVQ or HND or HNC or equivalent 0.0 0.0 0.0 -0.1 0.2
Commuting to job workplace: Car/motor vehicle 0.4 0.5 0.9 -1.0 0.2
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 0.3 -0.3 0.6
Medication: Aspirin 2.7 3.6 6.1 -2.5 -1.0
Supplements: Vitamin C 0.6 0.7 1.2 0.5 -1.1
Knee pain experienced in last month 1.4 2.2 4.4 -0.2 -2.1
Hypertension (Self-reported) 0.4 1.2 2.5 -1.6 0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.6 1.9 3.7 -1.9 -0.3
Illnesses of father: Heart disease 0.2 0.3 0.4 0.6 0.3
Illnesses of siblings: Diabetes 0.1 0.2 0.3 -0.3 0.5
Smoking status: Previous 0.5 0.8 1.5 -1.2 0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.7 1.4 2.6 -0.5 -1.6
Whole body fat-free mass 0.1 0.8 1.6 1.2 -0.2
Leg fat-free mass (right) 0.3 1.5 2.7 1.6 -0.5
Arm fat percentage (left) 0.4 1.8 2.5 -1.6 1.0
Average weekly red wine intake 2.6 3.9 5.8 2.4 -1.4
Handedness (chirality/laterality): Left-handed 0.1 0.2 0.3 0.3 -0.5
Mood swings 0.2 0.3 0.4 0.7 -0.3
Loneliness, isolation 1.0 1.4 2.7 -1.6 0.1
Long-standing illness, disability or infirmity 0.2 0.3 0.4 -0.3 -0.7
Ever had bowel cancer screening 0.0 0.0 0.0 0.1 -0.2
Diabetes diagnosed by doctor 0.0 0.0 0.1 -0.1 0.3
Ever had stillbirth, spontaneous miscarriage or termination 0.9 1.0 1.9 0.2 1.4
Friendships satisfaction 0.7 0.9 0.9 -0.9 0.9
Qualifications: nursing, teaching 1.7 2.7 5.3 2.3 0.2
Commuting to job workplace: Walk 1.9 2.1 4.1 2.0 0.1
Eye problems/disorders: Cataract 1.1 1.2 1.4 1.2 1.0
Mouth/teeth dental problems: Mouth ulcers 0.2 0.3 0.6 -0.3 -0.8
Medication for cholesterol 0.1 0.2 0.4 -0.6 0.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 0.3 -0.4 -0.5
Back pain experienced in last month 2.3 3.3 5.0 -1.3 2.2
Mineral and other dietary supplements 0.1 0.1 0.1 0.3 0.2
Breast cancer (self-reported) 0.2 0.2 0.4 -0.6 0.1
Asthma (self-reported) 3.2 6.3 7.1 -2.7 -2.3
Osteoporosis (self-reported) 3.6 4.4 8.5 2.9 0.5
Osteoarthritis (self-reported) 2.7 3.5 6.7 -0.5 2.6
Medication: Aspirin 3.5 4.6 8.3 -2.9 -0.9
Medication: Gliclazide 0.4 0.5 0.5 -0.7 0.7
Illnesses of father: None of the above (group 1) 0.1 0.1 0.3 0.2 0.5
Smoking status: Current 0.6 0.9 1.9 0.0 1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.3 0.6 -0.1 -0.8
Whole body water mass 0.2 0.9 1.8 1.3 -0.1
Leg predicted mass (right) 0.3 1.4 2.7 1.6 -0.5
Arm fat mass (left) 0.3 1.0 1.1 -1.0 1.0
Number of self-reported non-cancer illnesses 1.2 2.1 4.2 -2.1 -0.2
Average weekly champagne plus white wine intake 0.9 1.3 2.2 1.5 0.6
Miserableness 0.0 0.1 0.1 0.1 0.3
Guilty feelings 1.7 2.5 4.3 -0.9 2.1
Wears glasses or contact lenses 0.4 0.5 0.5 0.7 -0.7
Ever taken oral contraceptive pill 0.3 0.3 0.5 0.4 0.7
Hearing aid user 0.5 0.6 1.2 -0.0 1.1
Mother’s age at death 0.3 0.4 0.8 0.9 -0.3
Financial situation satisfaction 0.9 1.1 1.7 0.7 1.3
Tinnitus: Yes, now most or all of the time 0.6 0.8 1.2 1.1 0.6
Commuting to job workplace: Public transport 0.5 0.6 1.2 -0.3 -1.1
Eye problems/disorders: Glaucoma 1.4 1.7 3.3 -1.8 0.0
Medication: Blood pressure 0.0 0.0 0.1 0.1 0.3
Pain type(s) experienced in last month: Hip pain 2.3 2.9 4.2 -1.3 2.0
Supplements: Fish oil (including cod liver oil) 0.1 0.1 0.2 0.5 0.3
High cholesterol (Self-reported) 1.0 1.8 3.6 0.1 1.9
Medication: Bendroflumethiazide 0.6 0.9 1.8 -1.3 -0.2
Medication: Paracetamol 1.0 1.5 1.6 -1.2 1.3
Medication: Lisinopril 1.7 2.3 3.9 -0.8 -2.0
Medication: Atorvastatin 0.2 0.2 0.4 0.6 0.3
Illnesses of father: High blood pressure 1.7 2.1 3.0 -1.1 -1.7
Alcohol drinker status: Never 0.1 0.1 0.1 0.4 0.3
Ever smoked 0.2 0.4 0.5 -0.7 0.5
Basal metabolic rate 0.1 0.4 0.8 0.9 -0.0
Leg fat percentage (left) 1.1 3.9 4.3 -2.1 1.9
Arm fat-free mass (left) 0.1 0.5 0.8 0.9 0.3
Number of operations (self-reported) 1.4 2.0 3.5 0.7 1.9
Average weekly beer plus cider intake 1.5 2.2 4.3 -0.0 2.1
Irritability 0.5 0.8 0.8 0.9 0.9
Risk taking 0.0 0.0 0.0 0.1 0.2
Ever had prostate specific antigen (PSA) test 0.5 0.5 0.8 0.5 -0.9
Fractured/broken bones in last 5 years 3.4 4.4 4.8 2.0 2.2
Age started oral contraceptive pill 0.3 0.4 0.8 -0.9 0.0
Diastolic blood pressure, automated reading 0.0 0.0 0.1 -0.3 -0.1
Ever depressed for a whole week 0.7 0.8 1.6 -0.3 1.3
Unable to work because of sickness or disability 0.4 0.5 1.0 1.0 -0.0
Commuting to job workplace: Cycle 0.1 0.1 0.2 0.0 -0.5
Myopia 1.0 1.5 2.8 1.7 -0.3
Vascular/heart problems diagnosed by doctor 0.7 1.8 3.5 1.9 0.2
Cholesterol lowering medication 1.7 2.4 4.7 0.4 2.2
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 0.8 -0.5 0.9
Pain experienced in last month 0.6 1.0 1.8 1.3 -0.4
Supplements: Calcium 0.3 0.4 0.7 0.2 0.8
Basal cell carcinoma (self-reported) 0.8 1.0 1.5 -0.7 -1.2
Heart attack/myocardial infarction (self-reported) 0.4 0.5 0.9 -1.0 -0.3
Deep venous thrombosis (DVT) (self-reported) 2.7 3.5 6.2 0.9 2.5
Heart disease (siblings) 0.5 0.6 1.1 -1.1 0.2
Alcohol drinker status: Previous 0.6 0.7 1.2 -1.1 -0.4
Pack years of smoking 0.5 0.7 1.3 1.2 0.4
Impedance of whole body 0.4 2.2 4.3 -2.1 -0.3
Leg fat mass (left) 0.6 2.2 3.1 -1.8 1.1
Arm predicted mass (left) 0.1 0.5 1.0 1.0 0.3