Hub : Genes

TTC21A

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0630 0.0240 7.8e-04 0.010 0.024 0.022 0.028 0.026 1.7e-02 5.8e-04 1.0e-03 1.9e-04 3.6e-04
2 GTEx Adipose Subcutaneous 0.1610 0.0480 2.4e-06 0.048 NA 0.042 NA 0.046 8.4e-05 NA 2.2e-04 NA 1.2e-04
3 GTEx Adrenal Gland 0.2417 0.0837 8.5e-04 0.107 NA 0.132 NA 0.116 1.2e-04 NA 1.9e-05 NA 6.0e-05
4 GTEx Artery Tibial 0.1416 0.0412 2.2e-05 0.030 NA 0.101 NA 0.082 2.0e-03 NA 2.7e-08 NA 5.5e-07
5 GTEx Brain Cerebellar Hemisphere 0.2750 0.0880 1.0e-03 0.072 NA -0.006 NA 0.142 6.5e-03 NA 4.8e-01 NA 1.8e-04
6 GTEx Cells Transformed fibroblasts 0.1810 0.0430 2.6e-10 0.162 NA 0.160 NA 0.189 3.2e-12 NA 4.8e-12 NA 3.6e-14
7 GTEx Colon Transverse 0.1990 0.0740 1.7e-04 0.037 NA 0.080 NA 0.089 7.4e-03 NA 1.2e-04 NA 5.1e-05
8 GTEx Esophagus Mucosa 0.1960 0.0500 2.1e-10 0.153 NA 0.141 NA 0.149 2.2e-10 NA 1.2e-09 NA 3.6e-10
9 GTEx Lung 0.1005 0.0432 5.7e-03 0.001 NA 0.024 NA 0.013 2.5e-01 NA 5.3e-03 NA 3.5e-02
10 GTEx Muscle Skeletal 0.0813 0.0252 7.5e-05 0.066 NA 0.042 NA 0.055 5.1e-07 NA 5.1e-05 NA 4.0e-06
11 GTEx Nerve Tibial 0.3277 0.0643 4.4e-12 0.112 NA 0.199 NA 0.175 2.5e-08 NA 4.7e-14 NA 1.8e-12
12 GTEx Pancreas 0.1650 0.0730 3.2e-03 0.115 NA 0.066 NA 0.098 1.5e-05 NA 9.8e-04 NA 6.1e-05
13 GTEx Skin Sun Exposed Lower leg 0.0570 0.0260 5.6e-03 0.063 NA 0.045 NA 0.045 5.8e-06 NA 1.1e-04 NA 1.2e-04
14 GTEx Stomach 0.2220 0.0700 4.5e-04 0.054 NA 0.025 NA 0.049 1.4e-03 NA 2.3e-02 NA 2.3e-03
15 GTEx Testis 0.3330 0.0780 6.4e-07 0.183 NA 0.171 NA 0.187 1.5e-08 NA 4.8e-08 NA 9.9e-09
16 GTEx Thyroid 0.1040 0.0310 7.1e-06 0.089 NA 0.089 NA 0.095 2.5e-07 NA 2.7e-07 NA 1.0e-07
17 METSIM Adipose 0.0702 0.0243 2.3e-04 0.032 0.017 0.015 0.021 0.024 1.1e-05 1.2e-03 2.1e-03 2.9e-04 1.3e-04
18 ROSMAP Brain Pre-frontal Cortex 0.2055 0.0408 2.2e-16 0.098 0.163 0.158 0.162 0.146 1.3e-12 2.0e-20 7.9e-20 3.0e-20 2.9e-18
19 YFS Blood 0.0393 0.0133 1.4e-05 0.020 0.015 0.017 0.018 0.018 2.0e-07 6.3e-06 1.6e-06 7.6e-07 9.7e-07
20 TCGA Bladder Urothelial Carcinoma 0.0750 0.0400 1.2e-03 0.002 0.024 0.001 NA 0.004 2.1e-01 3.9e-03 2.7e-01 NA 1.4e-01
21 TCGA Breast Invasive Carcinoma 0.0334 0.0161 6.3e-06 0.036 0.023 0.030 NA 0.032 6.0e-08 1.3e-05 7.1e-07 NA 2.6e-07
22 TCGA Kidney Renal Clear Cell Carcinoma 0.0594 0.0307 1.6e-05 0.040 0.041 0.040 NA 0.034 2.5e-05 1.9e-05 2.3e-05 NA 8.4e-05
23 TCGA Kidney Renal Papillary Cell Carcinoma 0.2080 0.0700 3.3e-09 0.178 0.164 0.168 NA 0.173 1.9e-10 1.1e-09 7.0e-10 NA 3.5e-10
24 TCGA Brain Lower Grade Glioma 0.0532 0.0306 8.7e-03 0.007 0.017 0.017 NA 0.004 4.3e-02 4.6e-03 4.3e-03 NA 1.1e-01
25 TCGA Lung Adenocarcinoma 0.0819 0.0518 2.1e-04 0.039 0.034 0.036 NA 0.053 2.2e-05 7.1e-05 3.8e-05 NA 7.2e-07
26 TCGA Lung Squamous Cell Carcinoma 0.0278 0.0198 1.8e-03 0.030 0.022 0.015 NA 0.021 2.4e-04 1.5e-03 6.9e-03 NA 1.5e-03
27 TCGA Pancreatic Adenocarcinoma 0.1680 0.0730 2.5e-05 0.140 0.124 0.146 NA 0.141 1.8e-06 7.1e-06 1.1e-06 NA 1.6e-06
28 TCGA Pheochromocytoma and Paraganglioma 0.0530 0.0350 6.6e-03 0.061 0.042 0.041 NA 0.041 1.9e-03 8.6e-03 9.8e-03 NA 9.4e-03
29 TCGA Prostate Adenocarcinoma 0.0568 0.0280 7.1e-06 0.044 0.061 0.030 NA 0.054 1.8e-05 5.0e-07 3.5e-04 NA 2.7e-06
30 TCGA Thyroid Carcinoma 0.1330 0.0520 2.1e-13 0.157 0.154 0.142 NA 0.151 4.0e-15 7.9e-15 1.0e-13 NA 1.7e-14

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Bipolar Disorder (2018) 0.4 0.6 2.4 -1.4 -0.6 -0.7 0.9 -0.3 -0.6 -0.5 -0.5 -1.3 -0.8 -0.7 -1.1 -0.9 -0.1 -0.1 -0.7 -0.7 -0.7 -1.2 0.4 -0.1 0.4 -0.1 -0.9 -1.5 -0.2 -0.7 0.1 -0.5 -0.6
Bipolar Disorder or Schizophrenia 0.3 0.7 6.0 -2.4 0.1 -0.4 0.7 -0.6 0.6 0.1 -0.2 -1.7 -0.6 0.5 -0.9 -0.4 1.4 0.2 -0.7 0.5 -0.9 -0.3 -1.4 -0.4 -0.2 -0.0 -0.8 -1.4 0.2 -1.0 0.2 -0.4 -0.8
Depressed Affect (Nagel 2018) 0.4 0.8 4.3 -2.1 0.7 1.1 -0.6 -0.1 1.6 0.9 0.6 0.7 0.2 1.7 0.1 0.4 1.0 -0.2 0.0 1.4 -1.7 0.6 -1.5 -0.1 -0.4 -0.3 0.0 -0.4 0.8 -0.8 0.4 -0.1 -0.2
Depression (Nagel 2018) 0.5 0.8 1.9 -1.1 0.3 0.4 0.9 0.5 1.4 1.2 1.1 0.9 -0.4 1.2 -0.1 -0.1 -0.0 -0.9 1.0 1.1 -1.4 0.1 0.3 1.1 1.2 1.1 -0.7 0.3 1.3 0.3 1.2 1.2 1.0
Intelligence (Savage-Jansen 2018) 0.3 0.9 2.7 0.3 -0.5 -0.9 -0.7 -0.9 0.1 -0.1 0.4 0.9 -0.0 -0.1 0.2 -0.0 -1.4 -1.2 0.8 -0.2 0.4 -1.5 1.2 1.5 1.6 1.5 -1.0 0.8 1.3 0.6 1.1 1.4 1.4
Neuroticism (Nagel 2018) 0.5 1.2 5.1 -2.3 0.1 0.6 -0.7 0.1 0.2 -0.4 -0.8 -0.1 -0.5 0.5 -0.7 -0.3 -0.3 1.0 -1.2 0.7 -2.2 0.4 -1.7 -1.0 -1.5 -1.2 0.0 -1.4 -0.8 -1.8 -1.0 -1.5 -1.3
Schizophrenia (2018) 0.3 0.7 4.4 -2.0 0.6 0.1 0.3 -0.4 1.3 0.5 0.1 -1.2 -0.0 1.2 -0.3 0.2 1.9 0.4 -0.4 1.2 -0.6 0.5 -2.1 -0.4 -0.6 -0.0 -0.2 -0.5 0.5 -0.7 0.1 -0.1 -0.6
Schizophrenia vs Biploar Disorder 0.5 0.6 2.7 1.6 -0.2 -0.6 -1.1 0.1 -1.3 -1.3 -0.8 -0.3 0.2 -0.4 0.2 0.1 0.2 0.8 -0.2 -0.6 1.0 -0.5 -0.1 -0.8 -1.2 -0.7 0.9 0.1 -1.5 -0.4 -1.4 -0.9 -0.4
Worry (Nagel 2018) 0.5 1.1 2.7 -1.3 -0.8 -0.3 -1.1 -0.0 -1.1 -1.4 -1.3 0.0 -0.9 0.1 -1.2 -0.9 -0.3 1.0 -1.3 -0.7 -1.7 -0.8 -0.9 -1.0 -1.2 -1.1 -0.4 -1.6 -1.2 -1.4 -1.1 -1.4 -1.1
Alzheimer’s Disease (in mother) 1.0 1.2 5.0 -0.4 -0.9 -1.8 -0.4 0.2 -0.7 -1.0 -1.2 -0.9 -0.6 -0.6 -0.8 -0.6 0.4 1.4 -1.7 -0.3 0.3 0.2 -2.2 -1.1 -1.7 -1.3 0.1 -0.8 -1.6 -1.4 -1.5 -1.4 -1.2
Alzheimer’s Disease (in father) 0.9 1.0 4.4 0.0 0.6 0.5 0.6 1.5 -0.1 0.0 -0.3 -0.9 0.6 -0.3 0.5 0.6 0.8 0.4 -0.8 0.2 0.6 0.3 -0.4 -1.8 -1.6 -2.1 1.5 -0.9 -1.0 -0.7 -0.5 -2.1 -1.6
Alzheimer’s Disease (including proxy) 1.2 1.7 7.3 -0.7 -0.1 -0.6 0.5 1.0 0.1 -0.2 -0.8 -1.1 -0.1 -0.1 -0.2 -0.0 0.9 1.2 -1.6 0.5 -0.2 0.5 -2.7 -2.1 -2.4 -2.4 1.1 -1.1 -1.5 -1.6 -1.2 -2.3 -1.8
Crohns Disease (2017) 1.1 2.3 7.2 0.3 0.5 0.4 -0.3 1.7 -0.7 -0.4 -0.7 -2.3 0.5 0.1 0.1 0.4 0.2 1.5 -1.6 -0.1 0.9 1.1 -1.8 -2.4 -2.4 -2.4 1.6 -2.2 -2.1 -1.8 -1.8 -2.7 -2.6
Irritable Bowel Disease (IBD) 0.6 1.5 5.8 -1.2 -0.8 -0.9 -1.3 -0.2 -0.8 -1.1 -1.2 -1.0 -0.9 0.1 -1.1 -0.8 -0.1 1.4 -1.7 -0.6 -0.6 -0.1 -2.4 -1.1 -2.0 -1.2 0.2 -0.8 -1.9 -1.9 -1.7 -1.8 -1.4
Ulcerative Colitis (UC) 0.7 1.4 4.8 -2.2 -1.3 -1.4 -1.5 -1.6 -0.5 -1.2 -1.1 0.7 -1.7 -0.0 -1.6 -1.5 -0.5 0.8 -1.1 -0.9 -1.9 -1.1 -1.9 0.4 -0.8 0.3 -1.2 0.6 -0.9 -1.4 -0.9 -0.3 -0.0
Major Depression (MDD) 0.8 1.0 9.1 -2.3 -0.5 -0.8 -1.6 -0.5 0.7 -0.1 -0.3 0.6 -1.0 -0.4 -0.8 -0.8 -3.0 -0.1 -0.5 0.1 -1.8 -0.8 -1.6 0.1 -0.3 0.1 -0.6 0.2 0.1 -0.6 0.3 -0.1 0.1
Reaction Time 0.4 0.9 3.4 0.2 -0.1 0.4 1.9 -1.5 1.0 1.0 0.9 1.4 0.1 1.6 0.2 0.1 0.9 -1.0 1.2 0.4 0.3 -0.7 -0.3 0.9 0.8 1.0 0.1 0.8 0.6 1.1 0.9 1.4 1.2
Verbal and Numeric Reasoning (VNR) 1.6 3.7 10.3 0.7 -0.5 -0.6 0.5 -1.4 1.2 1.0 1.6 2.9 0.3 0.5 0.6 0.3 -1.3 -2.7 2.0 0.0 -0.0 -2.4 1.7 2.9 3.0 2.9 -1.3 2.7 2.6 2.0 2.8 3.0 3.2
Breast Cancer 0.4 0.9 3.2 0.2 -0.5 -0.6 1.2 -1.1 0.3 0.4 0.6 0.3 -0.0 -0.1 0.3 -0.0 -0.5 -1.4 0.8 -0.2 0.9 -1.7 0.4 1.6 1.3 1.8 -1.1 1.1 1.1 -0.0 1.1 1.1 1.6
Ovarian Cancer 1.0 1.3 3.6 -0.7 -1.4 -0.1 -0.4 -1.9 -0.1 -0.0 -0.0 1.8 -1.0 -0.4 -0.6 -0.9 0.2 -1.0 0.6 -0.6 -1.4 -1.8 0.9 1.5 1.5 1.5 -1.4 1.8 1.1 0.7 1.2 1.2 1.5
Prostate Cancer 0.2 0.3 0.8 -0.3 -0.2 -0.8 -0.3 0.0 0.6 0.4 0.3 0.8 -0.2 0.1 -0.0 -0.2 -0.8 -0.2 -0.0 0.6 -0.6 -0.2 -0.0 0.7 0.7 0.6 -0.6 0.5 0.2 0.6 0.3 0.9 0.7
Age at First Birth 0.3 0.5 2.0 0.5 0.5 1.2 1.0 0.2 0.9 1.0 0.8 -0.5 0.7 1.3 0.1 0.5 1.4 -0.6 0.2 0.5 0.4 -0.3 -0.7 0.0 -0.2 0.1 0.1 1.1 0.3 -0.3 0.6 -0.2 0.4
Bipolar Disorder (2011) 1.0 1.0 7.2 -0.2 0.7 0.3 0.6 1.0 0.1 0.0 -0.3 -2.7 0.3 0.4 0.0 0.3 1.2 0.9 -1.0 0.2 -0.4 0.8 -0.9 -1.5 -1.2 -1.4 0.8 -1.7 -0.9 -0.8 -0.7 -1.5 -1.6
Body Mass Index (BMI) (2010) 0.4 0.5 2.5 -0.1 -1.0 -0.5 1.3 -0.7 -0.7 -0.4 -0.4 -1.6 -1.0 -0.6 -0.8 -1.1 -1.2 0.1 -0.4 -0.9 -0.7 -0.4 -0.2 0.8 0.3 0.7 -1.0 0.5 -0.3 -0.4 -0.2 0.1 0.4
Coronary Artery Disease (CAD) 3.9 4.6 13.5 3.2 1.2 1.3 2.1 0.1 1.9 2.2 2.5 2.7 2.2 3.0 2.1 2.2 3.7 -2.3 2.4 1.5 2.9 0.2 0.9 1.4 1.2 1.0 1.6 2.9 1.4 3.0 2.1 1.9 2.2
Crohns Disease (2012) 0.4 0.6 2.8 -0.4 -0.7 -0.1 -0.8 -0.1 -0.6 -0.5 -0.9 -1.7 -0.5 -0.1 -0.8 -0.5 1.3 0.7 -1.3 -0.3 -0.3 -0.5 -0.8 -0.7 -0.8 -0.7 -0.3 -0.5 -1.0 -1.4 -0.8 -1.2 -0.9
Mean Putamen Volume 1.1 1.3 4.7 -0.8 -0.2 -0.1 0.4 0.1 -0.7 -0.8 -1.2 -1.8 -0.7 -1.4 -0.7 -0.6 -0.8 1.2 -1.4 -0.2 0.3 0.3 -2.2 -1.4 -1.8 -1.3 0.3 -1.4 -1.5 -1.6 -1.4 -1.6 -1.4
Fasting Glucose 0.5 0.6 4.6 1.7 -0.1 -1.2 0.7 -0.5 -0.7 -0.5 -0.1 -0.5 0.2 0.1 0.0 -0.0 0.5 -0.3 0.1 -0.8 2.1 -1.4 0.7 -0.6 -0.3 -0.4 1.1 0.0 -1.0 0.9 -0.1 -0.4 0.0
HbA1C 0.8 0.8 4.8 0.9 1.0 0.8 0.5 0.2 0.5 0.8 1.1 2.2 1.2 0.4 1.3 1.3 0.2 -0.9 1.5 0.7 1.0 0.3 1.5 0.7 0.7 0.6 0.9 -0.5 0.5 0.7 0.4 0.7 0.3
HDL Cholesterol 1.4 2.4 9.4 -0.3 -1.0 -0.7 -1.6 0.2 -1.9 -2.0 -1.8 -1.0 -1.3 -1.6 -1.4 -1.3 0.6 2.1 -1.9 -1.0 -0.0 0.3 -0.3 -1.8 -1.3 -1.9 -0.2 -3.1 -2.1 -1.5 -2.0 -1.9 -2.2
LDL Cholesterol 0.1 0.2 1.6 -0.1 0.4 0.5 1.1 0.8 0.5 0.5 0.4 -1.2 0.1 0.7 -0.0 0.1 0.1 -0.4 0.1 0.4 -0.1 0.6 -0.6 -0.2 -0.3 -0.2 0.4 0.2 -0.1 -0.2 0.3 -0.3 -0.0
Lupus 1.3 1.9 6.2 -1.1 0.3 0.1 -0.0 -1.8 1.7 1.3 1.1 1.8 -0.2 1.3 0.1 0.1 0.6 -1.4 1.1 0.5 -0.1 -1.3 0.8 1.4 2.0 1.9 -1.0 1.7 2.5 1.7 2.3 2.2 1.8
Neuroticism (2016) 0.4 0.6 1.9 -0.9 0.7 0.7 0.9 0.6 1.2 0.9 0.9 1.4 0.0 0.8 0.4 0.2 -1.0 -0.7 0.9 1.2 -1.0 0.6 0.0 0.7 0.5 0.5 -0.2 0.7 1.1 -0.1 0.7 0.7 0.7
Primary Biliary Cirrhosis 0.6 0.9 3.4 1.5 1.8 1.1 0.6 0.8 0.9 0.8 1.1 -0.8 1.4 0.9 1.4 1.4 0.6 -0.7 0.7 1.4 0.8 0.9 0.2 -0.1 0.1 -0.4 1.4 -0.1 0.3 0.8 0.6 0.2 0.2
Rheumatoid Arthritis 1.0 1.4 4.8 -0.1 0.8 1.0 1.0 -0.4 1.9 1.8 1.4 2.2 0.7 1.5 1.0 0.9 0.7 -1.1 1.3 1.8 -0.2 0.6 -0.3 1.0 0.8 1.0 0.0 1.7 1.8 0.6 1.4 1.3 1.3
Schizophrenia (2014) 0.4 0.8 4.2 -2.0 -0.0 -0.7 0.1 -0.6 0.2 -0.4 -0.7 -0.9 -0.7 0.3 -1.1 -0.6 1.7 0.9 -1.1 0.4 -1.0 -0.2 -1.7 -0.6 -0.9 -0.4 -0.6 -0.7 -0.4 -1.1 -0.6 -0.8 -1.0
Triglycerides 0.5 0.9 3.5 0.6 0.4 0.1 0.7 -0.1 1.1 1.0 1.2 0.1 0.7 0.5 0.7 0.7 0.2 -1.2 1.2 0.5 0.5 0.1 1.0 0.9 1.1 0.9 -0.1 1.8 1.9 0.7 1.5 1.0 1.2
Type 2 Diabetes (T2D) (2012) 0.1 0.2 0.6 0.8 -0.7 -0.3 0.1 -0.5 -0.3 -0.5 -0.1 0.6 0.1 -0.1 -0.6 -0.0 -0.3 0.3 0.5 -0.5 0.6 -0.2 0.0 0.7 0.1 0.2 -0.6 0.6 0.1 0.0 -0.3 0.3 0.4
Ulcerative Colitis 0.8 1.2 3.3 -1.2 -1.5 -1.4 -1.8 -1.7 -0.4 -0.8 -0.5 1.7 -1.4 0.1 -1.3 -1.3 0.4 -0.1 -0.4 -0.6 -1.2 -1.7 -0.6 1.3 0.5 1.2 -1.4 1.3 -0.3 -0.2 -0.1 0.8 1.1
Blood Eosinophil Count 1.0 8.0 19.4 2.9 2.1 2.2 2.8 1.0 3.1 3.3 3.9 2.9 3.1 3.2 3.5 3.1 0.5 -3.8 3.8 2.2 2.3 -0.5 2.5 1.9 2.9 2.1 2.2 1.6 2.8 4.4 3.6 3.2 2.7
Blood Platelet Count 0.7 8.7 27.0 2.7 3.8 3.0 -2.1 4.1 1.3 1.6 2.0 -0.5 4.0 1.4 3.4 4.0 2.6 0.5 0.2 3.4 5.2 4.1 3.4 -3.5 0.1 -3.4 4.0 -4.7 0.4 2.8 0.6 -1.2 -3.0
Blood Red Count 0.7 6.3 20.2 2.8 4.5 3.2 2.2 2.5 2.9 3.0 2.4 1.5 3.4 2.8 3.2 3.5 2.0 -0.5 1.2 3.9 3.4 3.4 1.0 -1.7 -0.2 -2.0 3.0 -1.7 1.5 1.5 1.2 -0.3 -0.9
Blood White Count 1.2 8.9 18.2 2.5 2.7 3.5 0.8 2.4 3.5 4.0 4.3 2.5 3.7 2.8 3.7 3.7 0.6 -3.2 3.2 3.7 2.2 1.8 3.9 1.1 3.6 1.2 1.8 -0.7 3.5 4.2 3.9 2.9 1.6
Heel T-Score 0.2 1.2 4.5 -0.9 -0.9 0.3 1.0 -2.0 0.4 0.4 0.3 0.3 -1.1 -0.4 -1.0 -1.0 -0.6 -0.5 0.2 0.1 -0.9 -0.6 1.1 1.7 2.0 1.7 -2.1 1.1 1.5 0.2 1.1 1.6 1.3
BMI 0.5 2.7 8.2 -0.3 1.7 2.9 1.9 -0.4 2.6 2.2 2.0 2.2 1.5 1.5 1.5 1.6 -1.2 -2.0 2.0 1.9 0.4 1.2 0.5 1.0 1.2 0.8 0.7 1.0 2.5 1.3 2.1 1.5 1.2
Height 0.2 4.6 11.6 0.9 -0.8 -0.0 0.9 -1.8 1.0 1.2 1.5 3.3 -0.3 -0.1 0.5 -0.2 -1.9 -3.0 2.3 -0.3 0.5 -2.4 2.5 2.6 3.4 2.6 -0.9 3.2 2.9 3.3 3.3 3.2 3.3
Waist Hip Ratio (WHR) 0.3 1.3 3.6 1.1 1.8 0.4 0.4 1.8 0.5 0.8 0.6 0.3 1.2 0.6 1.2 1.2 1.2 0.1 -0.4 1.4 1.6 1.1 0.8 -1.6 -0.4 -1.5 1.8 -1.9 -0.6 1.1 -0.1 -0.8 -1.3
Systolic Blood Pressure 0.4 2.2 4.3 1.4 1.7 2.0 1.1 1.8 1.6 1.9 1.7 2.1 1.4 1.5 1.2 1.5 0.4 -0.5 1.8 2.1 1.9 1.9 1.9 0.4 1.1 0.4 0.7 -0.1 1.8 1.7 1.1 1.4 0.7
Smoking Status 0.6 1.5 5.2 -0.2 1.4 1.1 1.0 2.3 2.0 1.7 1.1 1.0 1.2 1.6 1.1 1.4 1.6 -0.1 0.4 2.1 1.7 1.4 -1.2 -1.1 -0.8 -1.0 1.3 -0.2 0.7 0.2 0.5 -0.4 -0.5
Allergy or Eczema 1.1 3.0 9.2 0.2 -0.1 0.1 0.4 -0.8 1.1 1.1 1.6 2.0 0.1 1.0 0.4 0.2 1.1 -2.4 2.1 0.4 0.4 -2.0 1.8 2.9 3.0 3.0 -1.4 1.5 2.3 1.0 2.3 2.8 2.9
Cardiovascular Disease 0.7 2.2 13.1 -0.7 0.7 0.9 0.9 -0.6 2.0 1.7 1.5 3.6 0.6 2.0 0.5 0.8 0.9 -1.4 1.6 1.2 -0.1 0.3 1.4 1.5 2.0 1.3 -0.7 0.1 2.7 1.1 2.0 2.1 1.3
Hypothyroidism (self reported) 1.1 2.4 13.1 0.1 0.2 1.0 -1.5 0.2 0.7 1.0 1.6 1.9 0.9 0.8 1.2 1.0 -0.1 -1.7 2.2 0.8 0.1 -0.3 3.6 1.9 2.9 1.8 0.1 -0.3 1.6 2.5 1.7 2.7 1.7
Respiratory disease 0.4 0.9 3.8 -0.9 -0.6 -0.3 -0.2 -1.1 0.6 0.4 0.2 0.7 -0.8 0.3 -0.7 -0.7 0.1 -1.0 0.6 -0.2 -0.1 -2.0 0.6 1.0 1.5 1.1 -1.6 0.5 1.9 0.4 1.5 1.3 1.1
Type 2 Diabetes (T2D) (2018) 1.5 2.7 5.2 1.1 2.0 2.3 2.2 -0.5 2.3 2.2 2.2 2.1 1.7 2.2 1.7 1.8 0.6 -2.1 2.1 1.6 1.1 0.2 0.8 1.0 1.3 0.8 1.2 0.3 1.9 1.9 2.2 1.4 1.3
Lung FEV1/FVC ratio 0.3 1.4 6.4 -0.9 -1.6 -1.2 0.3 -1.9 -1.1 -1.1 -1.1 1.4 -1.4 -2.0 -1.3 -1.4 -2.5 0.4 -0.5 -1.4 -1.6 -0.8 0.4 0.9 0.3 0.7 -1.3 -0.1 -0.7 -0.9 -0.7 0.1 0.3
Lung FVC 1.6 8.3 17.2 -3.5 -4.1 -3.0 -3.2 -2.2 -3.1 -3.7 -3.7 -1.9 -4.0 -3.3 -4.0 -4.0 -2.0 2.9 -2.8 -3.2 -3.4 -1.5 -2.0 -0.1 -1.5 -0.0 -3.2 -1.0 -2.7 -3.8 -3.2 -1.5 -1.2
Neuroticism 0.4 0.9 3.8 -1.5 0.5 0.3 -0.6 0.0 -0.1 -0.6 -0.7 0.4 -0.1 0.9 -0.4 -0.0 1.2 0.7 -1.0 0.4 -1.3 0.0 -1.5 -1.2 -1.5 -1.3 0.2 -1.4 -0.7 -1.9 -0.7 -1.7 -1.2
Chronotype (morning person) 0.8 1.9 4.5 2.0 1.6 1.4 0.3 0.1 1.6 1.4 1.9 0.3 2.1 2.1 2.1 2.1 1.3 -1.4 1.7 1.2 1.4 0.4 0.7 0.5 0.8 0.7 1.7 0.2 0.8 1.9 1.3 1.2 1.0
Hair Pigment 0.1 1.9 6.4 0.7 0.5 0.7 1.9 -0.1 1.5 1.7 1.5 1.5 0.9 1.4 0.9 0.9 -0.1 -1.5 1.5 0.8 0.3 -0.0 1.0 1.5 1.6 1.6 -0.3 2.5 1.9 1.6 1.9 1.9 2.1
Tanning 0.0 0.3 1.9 -0.8 -0.3 0.0 -1.4 -1.2 0.2 0.1 0.0 -0.9 -0.1 -0.4 -0.3 -0.1 -0.5 0.4 -0.1 0.1 -0.7 0.6 0.0 -0.2 0.3 0.4 -0.7 -0.7 0.3 -0.1 -0.1 0.4 -0.2
Hand grip strength (left) 1.9 5.1 15.7 -2.1 -3.0 -2.5 -0.9 -4.0 -1.2 -1.5 -1.2 0.5 -3.0 -1.8 -2.4 -3.0 -1.8 -0.8 0.2 -2.8 -3.0 -3.8 0.3 2.9 1.7 2.8 -3.4 2.6 0.8 -0.9 0.5 1.9 2.3
Number of treatments/medications taken 0.4 0.6 3.9 -1.8 0.3 0.9 -0.3 0.4 1.2 0.8 0.3 1.1 -0.2 0.8 0.0 0.1 0.3 -0.2 0.1 1.2 -0.3 -0.2 0.7 0.2 1.1 0.1 -0.5 -2.0 1.1 0.5 0.8 0.9 -0.1
Average weekly spirits intake 0.5 0.6 2.1 0.3 0.2 -0.1 -0.5 0.9 -0.5 -0.6 -0.9 -1.4 -0.1 -1.0 -0.4 -0.0 0.4 1.0 -0.8 -0.1 -0.1 0.0 -0.5 -1.0 -1.1 -1.2 0.2 -1.2 -0.8 -0.8 -0.9 -1.1 -1.0
Sensitivity / hurt feelings 0.5 0.8 3.1 0.2 1.8 1.0 1.3 1.0 0.7 0.7 0.4 0.1 1.1 0.8 1.1 1.2 0.6 0.3 0.0 1.4 -0.2 1.1 -0.4 -1.0 -1.1 -1.1 1.3 -0.1 -0.3 -0.8 -0.3 -1.1 -0.6
Frequency of depressed mood in last 2 weeks 2.0 2.8 5.5 -0.1 1.3 1.2 1.9 0.3 2.4 2.3 2.2 1.8 0.6 2.3 1.1 0.9 0.9 -2.3 2.2 1.7 -0.4 -0.3 0.5 1.9 1.9 1.9 -0.3 1.6 2.4 1.1 2.3 2.1 2.3
Hearing difficulty/problems: Yes 3.0 4.6 9.6 -2.5 -2.9 -2.5 -1.9 -1.7 -2.8 -3.1 -2.8 0.1 -3.0 -2.0 -3.0 -3.0 -0.2 2.1 -2.2 -2.9 -3.0 -1.6 -0.9 -0.2 -0.9 -0.1 -2.3 -0.7 -2.3 -2.2 -2.4 -1.2 -0.9
Relative age of first facial hair 0.3 0.6 2.2 -0.4 -0.7 -0.0 -1.1 -0.2 -0.9 -0.9 -1.0 0.3 -0.7 -0.2 -0.8 -0.7 1.5 1.1 -0.9 -1.0 -1.3 -0.3 -0.1 -0.5 -0.8 -0.5 -0.5 -0.1 -0.5 -1.3 -0.9 -1.1 -0.8
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 4.6 -1.2 -0.5 -0.1 0.1 -2.1 0.4 0.0 -0.1 1.6 -0.9 -0.0 -0.5 -0.7 -0.0 -0.3 0.6 -0.0 -0.5 -1.2 0.1 1.2 0.9 1.3 -0.9 0.4 0.7 0.2 0.4 1.3 1.0
Ever used hormone-replacement therapy (HRT) 1.3 1.6 4.6 -1.8 -0.3 0.5 -1.7 -0.3 -0.6 -1.1 -1.7 -0.2 -0.7 -0.9 -1.0 -0.5 0.1 1.8 -1.8 0.0 -0.2 -0.0 -1.4 -1.8 -1.7 -1.8 0.2 -2.2 -1.3 -1.3 -1.5 -1.7 -2.0
Ever had hysterectomy (womb removed) 0.9 1.0 2.4 0.1 0.3 0.7 -0.5 1.5 0.2 0.2 -0.4 -1.2 0.3 -0.2 0.7 0.5 0.3 1.3 -0.8 1.3 1.1 1.5 -0.6 -1.5 -1.2 -1.5 1.3 -1.4 -1.2 0.3 -1.1 -0.9 -1.4
Systolic blood pressure, automated reading 0.3 0.7 3.4 0.4 0.9 1.2 -0.6 1.3 0.5 0.5 0.0 0.6 0.7 0.0 0.4 0.8 0.4 1.2 -0.1 1.4 1.5 1.9 0.5 -0.9 -0.3 -1.0 0.8 -1.2 0.1 0.6 -0.5 -0.0 -1.0
Eye problems/disorders: Diabetes related eye disease 2.9 3.2 12.7 1.9 2.7 3.6 2.1 1.1 1.7 2.1 2.1 -0.4 2.6 1.7 2.5 2.5 1.3 -1.4 1.6 1.9 1.9 1.5 1.1 -0.5 0.5 -0.7 2.5 -0.2 1.2 2.0 1.6 0.3 -0.1
Angina 2.1 2.7 5.3 -0.9 -2.1 -2.0 -1.2 0.2 -2.2 -2.0 -2.1 -1.0 -1.9 -1.7 -2.1 -2.0 -0.2 2.1 -2.3 -1.5 -1.7 0.1 -0.7 -1.1 -1.4 -1.0 -1.1 -0.7 -2.3 -1.7 -2.2 -1.8 -1.6
Medication for hormone replacement therapy 2.0 2.2 4.8 -2.0 -1.8 -0.8 -1.2 -1.6 -1.3 -1.6 -2.0 -0.2 -1.9 -1.7 -2.2 -1.8 -1.0 2.0 -2.0 -1.2 -1.7 -0.1 -1.2 -0.7 -1.2 -0.6 -1.4 -1.0 -1.4 -2.1 -1.8 -1.2 -1.2
Vitamin and mineral supplements 1.0 1.4 3.5 1.0 1.3 1.9 1.0 1.1 1.7 1.7 1.7 1.4 1.5 1.6 1.4 1.5 0.3 -0.7 1.3 1.6 0.2 1.7 0.2 0.1 0.3 0.1 0.9 0.6 1.2 1.2 1.0 0.7 0.3
Supplements: Zinc 1.8 2.0 3.7 -0.7 -1.1 -1.8 -1.3 -0.7 -1.7 -1.9 -1.9 -0.9 -1.7 -1.6 -1.7 -1.7 0.3 1.8 -1.9 -1.4 0.4 -0.8 -0.6 -0.9 -1.1 -1.0 -1.0 -1.5 -1.8 -1.9 -1.8 -1.5 -1.3
Medication: Co-codamol 0.4 0.4 3.4 -0.2 0.8 1.8 0.1 0.2 0.6 0.4 0.1 -1.0 0.8 0.3 0.9 0.9 -0.0 0.4 -0.2 1.0 -0.1 1.0 -0.2 -0.4 -0.4 -0.4 0.5 -0.9 -0.1 -0.3 -0.3 -0.3 -0.7
Medication: Metformin 1.8 2.6 7.7 1.8 1.9 1.5 1.2 -0.5 1.8 1.7 2.1 1.8 1.8 1.8 2.0 1.8 0.5 -2.2 2.1 1.2 2.0 -0.0 1.0 0.7 1.3 0.8 1.6 0.7 1.5 2.8 2.1 1.5 1.4
Diabetes (father) 1.4 1.8 7.2 0.4 -0.3 0.1 0.5 -1.0 0.6 0.4 1.0 2.3 0.1 1.4 0.7 0.1 1.1 -1.7 1.8 -0.0 0.2 -2.1 1.0 2.1 1.4 2.0 -0.4 2.7 1.4 0.8 1.3 1.8 2.3
Diabetes (mother) 0.8 1.0 3.8 1.2 0.7 1.1 0.6 1.6 0.9 1.0 1.0 1.9 1.4 0.8 1.4 1.4 -0.6 -0.6 0.9 1.0 1.9 0.2 0.9 -0.4 0.1 -0.5 1.7 -0.0 0.3 1.3 0.6 0.2 0.1
Severe depression (siblings) 0.3 0.3 2.4 -1.0 -0.2 0.4 -1.5 0.2 0.1 -0.3 -0.3 0.1 -0.1 0.0 -0.1 -0.1 -1.0 0.3 -0.5 0.0 -0.6 0.0 -0.5 -0.6 -0.7 -0.8 0.4 0.1 -0.4 -0.1 -0.1 -0.9 -0.6
Pack years adult smoking proportion 0.8 1.3 3.2 0.6 1.1 0.6 1.7 0.4 1.7 1.8 1.7 1.0 0.7 1.7 1.2 0.9 0.8 -1.5 1.4 0.8 0.4 0.3 0.3 0.8 0.9 0.8 0.6 1.2 1.3 1.0 1.6 0.9 1.2
Impedance of leg (right) 0.5 2.4 10.8 3.1 1.6 0.4 1.1 3.3 0.1 0.8 0.7 0.5 2.1 1.3 1.7 2.0 1.4 0.3 -0.1 1.3 2.6 1.2 1.2 -1.7 -0.3 -1.8 2.5 -1.7 -0.7 1.7 -0.1 -0.5 -0.9
Leg fat-free mass (left) 0.3 1.8 5.2 -2.0 -0.2 0.7 -0.0 -2.3 1.1 0.6 0.5 2.1 -0.6 -0.4 -0.2 -0.5 -2.1 -1.6 1.2 -0.3 -1.6 -1.2 0.5 1.6 1.4 1.6 -1.3 1.6 2.3 0.3 1.8 1.3 1.5
Trunk fat percentage 1.0 4.2 9.9 1.8 3.1 2.7 0.9 2.3 2.3 2.4 2.2 2.0 2.8 2.1 2.7 2.9 0.6 -1.2 1.5 2.9 2.7 2.6 1.4 -0.9 0.6 -1.1 2.7 -0.8 1.6 2.5 1.6 0.6 -0.2
Hand grip strength (right) 1.4 3.7 12.7 -1.1 -2.3 -2.2 -0.8 -3.6 -1.2 -1.3 -0.8 0.4 -2.2 -2.0 -1.7 -2.3 -2.3 -1.0 0.4 -2.4 -2.1 -3.5 1.1 2.5 1.8 2.5 -2.8 2.1 0.8 -0.6 0.7 1.6 2.1
Townsend deprivation index at recruitment 2.6 3.6 8.7 1.8 1.7 1.4 2.0 0.1 1.9 2.1 2.5 1.9 2.2 1.8 2.1 2.1 0.8 -2.5 3.0 1.3 1.8 0.4 2.0 1.4 1.6 1.5 1.0 2.0 2.4 2.2 2.3 2.0 2.2
Current tobacco smoking 1.0 1.7 6.2 -0.9 1.3 0.7 0.9 1.9 2.5 2.1 1.3 1.9 1.1 1.9 1.1 1.3 2.0 -0.7 0.5 2.1 0.6 1.3 -1.7 -0.5 -0.2 -0.3 0.8 0.4 1.4 0.8 1.4 0.3 0.2
Average weekly fortified wine intake 0.1 0.1 1.0 1.0 0.2 -0.6 0.8 -0.4 -0.2 0.0 0.1 -0.2 -0.1 -0.0 0.2 -0.2 -0.3 -0.5 -0.1 -0.2 0.8 -0.4 -0.5 0.1 0.2 0.2 0.1 0.1 -0.2 0.3 0.3 0.1 0.2
Maternal smoking around birth 2.3 3.3 9.6 1.1 2.5 2.2 1.5 1.7 2.8 2.6 2.5 0.8 2.3 2.2 2.3 2.4 -0.4 -1.5 1.8 3.1 2.0 2.2 0.1 0.0 0.6 0.0 1.7 0.3 1.9 1.5 1.8 0.9 0.5
Fed-up feelings 1.4 2.5 7.7 -0.1 2.0 2.0 2.1 0.6 2.6 2.2 2.2 1.3 1.8 2.8 2.0 1.9 1.6 -2.1 1.9 2.2 -0.2 0.4 -0.3 0.6 0.5 0.6 1.2 0.4 1.6 0.5 1.8 0.8 1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.2 2.7 -0.5 0.9 0.5 1.6 -0.1 1.6 1.5 1.4 1.0 0.3 1.3 0.6 0.5 0.7 -1.5 1.4 1.0 -0.7 -0.4 0.2 1.2 1.1 1.2 -0.2 1.0 1.6 0.7 1.5 1.4 1.4
Relative age voice broke 0.3 0.4 4.0 0.4 -0.7 -0.0 -1.3 -0.6 -0.7 -0.8 -0.5 0.7 0.1 0.5 -0.3 -0.1 2.0 0.4 -0.3 -0.7 0.6 -0.6 -0.3 -0.2 -0.4 -0.2 0.0 -0.3 -0.6 -0.4 -0.6 -0.4 -0.2
Taking other prescription medications 0.3 0.5 2.2 -1.5 0.2 0.7 -0.5 -0.4 1.1 0.7 0.3 0.4 -0.4 0.6 0.2 -0.0 0.5 -0.3 0.5 1.0 -0.4 -0.1 0.3 0.4 1.0 0.4 -0.7 -1.2 1.3 -0.1 0.8 0.8 0.1
Age when periods started (menarche) 0.5 1.2 3.6 -0.3 0.1 -0.4 -0.9 -0.5 0.6 0.4 0.8 1.7 -0.4 -0.2 0.0 -0.3 -1.4 -1.4 1.0 0.3 -0.9 -1.3 1.7 1.7 1.9 1.7 -0.9 0.7 1.5 0.9 1.5 1.4 1.5
Bilateral oophorectomy (both ovaries removed) 0.6 0.6 2.3 0.3 0.8 1.2 -1.4 0.9 0.7 0.5 0.6 0.9 0.7 0.7 0.8 0.8 0.3 0.1 0.6 1.5 0.6 1.4 1.2 -0.5 0.4 -0.3 0.8 -0.8 0.5 1.2 0.3 0.4 -0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.3 1.1 -0.3 0.3 -0.0 -0.9 -0.7 0.2 0.3 0.3 -0.3 0.1 -0.1 -0.1 0.1 -0.6 0.3 -0.0 0.4 0.9 0.7 1.0 0.1 1.0 0.2 -0.5 -1.1 0.6 0.5 0.2 0.7 -0.2
Tinnitus: Yes, but not now, but have in the past 0.9 0.9 4.2 -0.4 1.1 1.1 1.8 0.2 1.6 1.6 1.1 0.3 0.5 2.0 0.6 0.7 2.1 -0.5 0.5 1.5 0.3 1.2 -0.2 0.3 0.2 0.4 0.0 0.6 1.1 -0.2 0.9 0.1 0.2
Qualifications: CSEs or equivalent 0.3 0.4 2.2 0.4 0.9 0.9 1.0 0.0 0.5 0.7 0.8 0.0 0.9 0.9 0.5 0.7 1.5 -1.1 0.6 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.3 0.3 0.7 -0.5 0.7 -0.3 0.2
Serious illness, injury or assault to yourself 0.9 1.1 4.6 -0.6 -1.7 -1.7 -0.9 -1.1 -1.3 -1.2 -1.0 0.8 -1.4 -1.4 -1.2 -1.4 -0.7 0.1 -0.3 -1.4 -1.0 -2.1 1.0 1.0 0.7 0.8 -1.3 0.5 -0.3 -0.3 -0.2 0.3 0.7
High blood pressure 0.4 1.2 3.4 -0.1 1.2 1.4 0.0 0.6 1.8 1.5 1.0 1.7 1.2 1.6 0.7 1.3 1.3 -0.4 0.6 1.9 1.4 0.9 0.3 -0.1 0.7 -0.2 0.3 -1.5 1.4 1.1 1.0 0.9 -0.0
Hayfever, allergic rhinitis or eczema 2.1 4.5 13.5 0.6 -0.1 0.4 0.7 -1.3 1.4 1.3 1.9 2.5 0.0 1.7 0.6 0.1 1.3 -2.9 2.7 0.6 -0.1 -2.4 1.9 3.5 3.4 3.7 -1.7 2.4 3.0 1.2 2.7 3.4 3.5
Multivitamins +/- minerals 0.9 1.1 3.5 -1.9 -1.3 -1.5 -1.3 -1.0 -0.9 -1.1 -1.1 -0.8 -1.5 -1.3 -1.4 -1.4 0.1 0.3 -0.6 -1.0 -1.3 -1.6 0.9 0.6 0.8 0.6 -1.8 -0.2 0.3 -0.9 -0.1 0.4 0.3
Stomach or abdominal pain in last month 0.4 0.5 2.7 1.0 0.9 0.2 0.4 0.8 -0.2 0.3 0.1 -0.7 0.6 0.0 0.8 0.7 0.9 0.6 -0.2 0.7 0.5 1.5 0.5 -0.4 -0.0 -0.4 0.7 -1.6 -0.8 0.6 -0.7 0.0 -0.6
Supplements: Glucosamine 5.9 7.7 16.9 -2.7 -3.4 -3.4 -3.5 -2.6 -3.9 -4.1 -3.8 -1.2 -3.7 -3.8 -3.5 -3.7 -1.3 2.7 -3.0 -3.3 -2.2 -2.1 -0.9 -0.3 -1.3 -0.5 -2.5 -1.5 -2.9 -2.8 -3.2 -1.6 -1.5
Diverticular disease/diverticulitis (self-reported) 1.1 1.3 4.6 0.7 1.6 1.7 2.1 0.3 0.6 0.8 0.4 0.0 1.5 1.4 1.5 1.5 2.1 0.4 0.2 1.5 0.5 1.3 -0.6 -1.0 -1.2 -1.1 1.6 -0.7 -0.5 -0.2 -0.6 -0.7 -0.7
Medication: Atenolol 1.8 2.3 5.5 -0.3 0.6 1.8 1.2 1.2 2.0 1.8 2.0 1.6 1.1 2.0 1.0 1.1 1.6 -1.4 1.9 1.9 0.2 1.1 1.5 1.5 1.9 1.4 -0.3 0.6 2.4 1.3 1.9 2.0 1.3
Medication: Levothyroxine sodium 0.7 1.1 5.4 0.7 0.4 0.7 0.3 -0.1 0.5 0.8 1.1 0.8 0.9 1.0 1.0 0.9 2.0 -1.0 1.5 0.4 0.7 -0.1 2.3 1.1 1.6 1.0 0.4 -0.9 0.8 1.5 0.8 1.6 0.8
Sitting height 0.5 3.6 11.4 -0.7 -1.9 -1.1 -0.6 -1.7 -1.0 -0.7 -0.1 3.1 -1.4 -1.9 -0.8 -1.5 -3.4 -1.7 1.0 -2.2 -2.2 -2.8 3.0 2.2 2.5 2.1 -2.2 2.1 1.6 0.4 1.6 1.4 2.1
Chronic bronchitis/emphysema (father) 3.3 3.9 10.9 -2.5 -1.0 -1.0 -1.6 0.1 -1.8 -1.9 -2.4 -0.5 -1.3 -1.8 -1.6 -1.4 -0.9 2.3 -2.8 -1.5 -1.8 -0.3 -1.9 -1.9 -2.4 -1.9 -0.6 -2.7 -2.3 -3.3 -2.4 -2.9 -2.6
High blood pressure (mother) 1.0 1.4 4.4 -0.8 -1.0 -1.0 -0.8 -1.4 -1.0 -0.9 -0.3 1.7 -1.1 -0.5 -1.1 -1.2 0.1 -0.9 0.3 -1.5 -1.2 -2.1 1.5 1.8 1.6 1.8 -1.8 1.1 0.5 0.0 0.6 1.1 1.4
Body mass index (BMI) 0.5 2.0 7.3 -0.1 2.4 2.7 0.8 0.1 2.5 2.0 1.7 0.7 1.7 1.4 1.7 1.9 0.1 -1.0 1.2 2.2 0.9 2.0 0.0 -0.3 0.3 -0.4 1.4 -0.3 1.7 1.2 1.4 0.5 -0.1
Impedance of leg (left) 0.4 1.9 10.0 2.4 1.3 0.2 0.5 3.2 -0.2 0.4 0.3 0.4 1.7 1.0 1.3 1.6 1.2 0.7 -0.5 1.1 2.2 1.3 0.9 -1.7 -0.7 -1.9 2.1 -1.8 -1.1 1.0 -0.6 -0.9 -1.2
Leg predicted mass (left) 0.3 1.8 5.2 -1.9 -0.2 0.7 -0.0 -2.2 1.1 0.6 0.5 2.1 -0.6 -0.5 -0.2 -0.5 -2.3 -1.7 1.2 -0.3 -1.6 -1.2 0.5 1.6 1.5 1.6 -1.3 1.6 2.3 0.3 1.8 1.4 1.5
Trunk fat mass 0.8 3.4 7.5 1.0 2.7 2.6 1.0 1.3 2.4 2.4 2.1 2.2 2.3 1.8 2.4 2.4 0.3 -1.6 1.7 2.5 2.0 1.9 1.5 -0.4 1.0 -0.5 2.0 -0.2 2.1 2.5 2.0 1.0 0.2
Waist circumference 0.3 1.1 3.5 0.1 1.8 1.9 0.1 0.7 1.4 1.2 1.0 0.7 1.2 0.7 1.2 1.3 0.0 -0.6 0.5 1.5 1.1 1.4 0.8 -0.6 0.4 -0.7 1.3 -1.1 0.9 1.6 1.0 0.2 -0.5
Number of incorrect matches in round 0.7 1.1 6.9 -2.6 -1.4 -0.1 -1.1 -0.3 0.2 -0.4 -1.0 -0.8 -1.4 -0.9 -1.5 -1.3 -0.6 1.0 -0.9 -0.0 -2.6 -0.4 -1.4 -0.1 -0.4 -0.1 -1.3 -0.1 0.2 -1.1 -0.4 -0.2 -0.4
Past tobacco smoking 1.2 2.2 5.3 -2.0 -1.9 -1.7 -0.7 -1.9 -1.7 -1.8 -1.9 -0.0 -2.1 -1.6 -2.0 -2.1 -0.9 0.6 -1.4 -2.3 -2.2 -1.4 -1.1 0.5 -0.3 0.6 -2.0 -0.2 -0.8 -1.7 -0.9 -0.5 -0.2
Alcohol usually taken with meals 1.8 2.9 7.9 0.2 -2.8 -2.7 -1.7 -1.3 -2.8 -2.6 -1.8 -0.2 -2.4 -2.2 -1.8 -2.5 -1.2 0.7 -0.6 -2.7 -0.7 -2.5 1.8 1.2 0.9 1.1 -1.8 0.4 -1.3 0.0 -1.2 0.7 0.7
Nervous feelings 0.1 0.2 1.3 -0.3 0.2 0.4 -0.1 0.6 -0.4 -0.5 -0.2 0.6 -0.0 1.1 -0.0 -0.1 1.2 -0.2 -0.1 -0.3 -0.4 -0.6 0.4 -0.3 -0.2 -0.2 0.2 -0.6 -0.1 -0.4 0.1 -0.6 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 1.6 -0.1 1.1 0.9 1.1 0.3 1.2 0.9 0.9 0.1 0.8 1.0 0.9 0.9 -0.6 -0.7 0.6 1.3 -0.2 0.3 -1.2 -0.5 -0.7 -0.4 1.1 0.5 0.4 -0.3 0.6 -0.4 0.1
Hearing difficulty/problems with background noise 0.4 0.6 2.2 -0.3 -0.3 -0.2 -1.3 0.2 -0.6 -0.9 -1.0 0.7 -0.7 -0.4 -0.8 -0.6 -0.9 1.4 -1.5 0.0 -0.3 -0.0 -0.5 -1.1 -0.8 -1.0 -0.3 -0.5 -1.2 -0.3 -1.1 -0.9 -0.8
Hair/balding pattern: Pattern 2 2.3 3.0 8.3 -0.9 0.3 -0.2 -0.6 1.7 -0.7 -0.8 -1.4 -2.0 -0.0 -1.0 -0.6 -0.0 -0.9 2.5 -2.3 0.1 -0.7 1.8 -1.8 -2.8 -2.6 -2.8 0.9 -2.4 -2.2 -1.8 -2.2 -2.8 -2.9
Had menopause 1.2 1.4 3.3 -1.8 -1.1 0.0 -1.6 -0.6 -0.6 -1.2 -1.6 -1.0 -1.6 -0.6 -1.8 -1.5 -0.0 1.5 -1.8 -0.2 -1.2 -1.0 -1.3 -1.0 -1.0 -1.0 -1.0 -1.0 -0.8 -1.5 -1.0 -1.2 -1.2
Had other major operations 0.3 0.3 1.4 0.5 -0.3 0.2 -0.5 1.2 -0.5 -0.5 -0.3 -0.6 0.1 -0.1 0.3 0.1 0.1 -0.1 -0.2 -0.2 0.1 -0.6 1.1 -0.6 -0.3 -0.8 1.2 -0.5 -1.1 0.6 -0.2 -0.7 -0.4
Forced vital capacity (FVC) 0.3 1.1 5.6 -1.3 -1.6 -0.7 -0.6 -1.0 -0.4 -0.6 -0.3 1.2 -0.9 -1.3 -0.6 -0.9 -2.4 -0.5 0.4 -1.2 -1.5 -1.9 0.3 1.1 0.5 1.2 -1.0 1.0 0.1 -0.8 0.1 0.4 0.9
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.3 1.7 -0.2 0.0 -0.0 -0.9 -0.6 0.2 0.3 0.3 0.1 0.0 -0.2 -0.3 -0.0 -0.4 0.2 0.2 0.3 0.7 0.4 1.3 0.5 1.2 0.5 -0.8 -0.6 0.7 0.7 0.2 1.0 0.2
Ever unenthusiastic/disinterested for a whole week 2.0 2.5 7.1 -2.7 0.1 -0.0 -0.8 1.4 -0.1 -0.7 -1.3 -1.9 -0.6 -0.9 -0.9 -0.5 0.2 1.8 -2.2 0.4 -1.5 1.0 -2.5 -2.4 -2.3 -2.3 0.4 -2.1 -1.3 -1.6 -1.3 -2.4 -2.6
Qualifications: None of the above 0.9 1.9 5.5 0.1 1.8 2.4 0.7 2.2 2.3 2.1 1.8 1.2 1.9 1.8 1.5 1.9 0.6 -0.9 0.9 2.3 0.6 1.9 0.1 -0.5 0.2 -0.4 1.1 -0.4 1.4 0.9 1.3 0.2 -0.2
Financial difficulties in last 2 years 1.8 2.4 5.4 1.3 1.8 1.8 1.6 0.7 1.9 2.1 2.3 0.3 2.0 2.0 2.0 1.9 0.9 -2.1 1.9 1.3 2.3 0.2 0.8 0.3 0.9 0.4 1.5 0.6 1.4 1.7 2.1 0.8 1.0
Mouth/teeth dental problems 0.8 1.2 3.9 1.5 -0.1 -0.6 -0.4 0.0 -1.4 -1.1 -1.0 -0.8 0.4 -0.6 0.2 0.3 0.9 1.7 -1.2 -0.8 0.9 0.9 0.2 -1.4 -1.3 -1.6 1.1 -0.9 -2.0 0.1 -1.7 -1.4 -1.4
Heart attack 0.1 0.2 0.9 0.1 -0.3 -0.8 0.3 0.3 -0.1 0.0 0.0 -0.6 -0.6 0.2 -0.3 -0.5 1.0 -0.4 -0.2 -0.4 -0.4 -0.2 0.3 0.3 0.6 0.2 -0.4 0.2 -0.0 0.5 0.4 0.3 0.3
Allergy 1.5 3.4 9.2 -1.2 0.1 -0.3 -0.4 0.9 -1.1 -1.1 -1.7 -2.1 -0.2 -1.4 -0.6 -0.2 -1.1 2.6 -2.5 -0.4 -0.9 2.1 -2.2 -2.9 -3.0 -3.0 1.1 -1.6 -2.5 -1.6 -2.5 -3.0 -2.9
Pain all over the body in last month 1.1 1.1 5.0 2.0 1.5 1.1 1.2 0.4 0.4 0.9 1.3 1.1 1.6 0.7 1.6 1.4 1.1 -1.3 1.2 0.2 2.2 -0.4 1.0 0.0 0.3 0.0 1.2 0.3 0.4 0.4 0.9 -0.1 0.4
Diabetes (self-reported) 1.1 1.7 6.2 0.7 0.9 1.7 1.3 -1.1 1.3 1.4 1.7 2.5 1.3 1.5 1.2 1.3 0.2 -1.8 1.8 0.8 0.8 -0.2 1.3 1.1 1.3 1.1 0.8 0.1 1.1 1.9 1.5 1.4 1.2
Hayfever/allergic rhinitis (self-reported) 1.8 2.4 7.8 0.5 0.2 0.3 -0.2 -1.0 1.1 1.0 1.5 1.4 0.1 1.0 0.5 0.2 -0.3 -1.8 2.0 0.7 -0.6 -1.1 1.7 2.8 2.7 2.7 -1.4 1.7 2.3 1.0 1.9 2.7 2.6
Medication: Ramipril 0.2 0.3 1.4 -0.4 0.1 0.3 -0.7 -0.7 -0.5 -0.4 -0.1 0.9 -0.3 -0.5 -0.2 -0.4 -0.8 -0.3 0.5 -0.9 -0.8 -0.4 1.2 0.8 0.7 0.8 -0.5 -0.1 0.2 -0.2 0.1 0.4 0.4
Medication: Simvastatin 0.6 0.9 3.9 0.4 1.1 1.5 2.0 0.6 1.3 1.0 0.4 0.3 0.7 1.6 0.4 0.8 0.9 0.3 0.2 1.7 0.8 1.5 -0.8 -1.0 -0.6 -1.0 1.1 -1.0 0.3 0.7 0.2 -0.2 -0.8
Fluid intelligence score 0.3 0.7 2.2 0.4 -1.2 -1.5 -0.5 -0.1 -0.7 -0.8 -0.1 0.3 -0.7 -0.6 -0.5 -0.8 -1.4 -0.6 -0.0 -1.2 -0.4 -1.1 0.6 1.0 1.1 1.1 -1.2 1.1 0.5 0.2 0.5 0.9 1.1
Illnesses of siblings 2.0 2.8 12.4 0.2 -0.2 -0.2 -0.2 -1.8 0.7 0.7 1.1 1.5 -0.2 0.3 0.4 -0.2 0.3 -2.0 2.2 -0.3 -1.0 -1.4 1.6 2.6 2.3 2.7 -1.4 3.5 2.5 1.4 2.2 2.6 3.0
Neuroticism score 0.3 0.6 2.5 -1.3 0.5 0.4 -0.5 0.0 0.2 -0.3 -0.3 0.9 -0.0 1.1 -0.1 0.0 0.9 0.1 -0.5 0.3 -1.5 -0.4 -1.5 -0.7 -1.2 -0.7 0.2 -0.8 -0.5 -1.6 -0.4 -1.3 -0.6
Weight 0.4 1.9 5.5 -0.2 1.8 2.4 0.5 -0.4 2.3 1.9 1.7 1.9 1.3 1.0 1.5 1.5 -0.7 -1.7 1.6 1.6 0.6 0.8 0.9 0.4 1.1 0.2 0.9 0.5 2.3 1.7 2.1 1.1 0.7
Impedance of arm (right) 0.5 2.2 9.5 3.1 1.1 -0.4 0.8 2.8 -0.2 0.7 1.4 1.6 1.7 1.3 1.7 1.5 1.7 -1.3 1.3 0.4 2.2 -0.3 2.7 -0.0 1.2 -0.1 1.5 0.6 0.4 2.4 1.1 0.8 0.9
Arm fat percentage (right) 1.0 4.0 9.9 1.3 3.1 2.7 1.1 1.4 2.6 2.6 2.4 1.5 2.6 1.9 2.6 2.7 0.9 -1.7 1.9 2.6 2.4 2.2 1.3 -0.4 0.9 -0.6 2.3 -0.4 2.1 2.6 2.1 1.0 0.2
Trunk fat-free mass 0.3 1.5 5.7 -2.1 -0.6 0.6 -0.0 -2.4 1.0 0.5 0.3 1.2 -0.8 -0.7 -0.5 -0.7 -2.0 -1.4 1.0 -0.5 -1.5 -1.6 0.2 1.4 1.2 1.4 -1.3 1.3 1.9 0.1 1.6 1.1 1.2
Hip circumference 0.3 1.1 3.8 -0.2 1.2 1.9 0.1 -0.0 1.6 1.4 1.3 1.2 0.8 0.7 0.8 0.9 -0.9 -1.3 1.2 1.3 0.3 0.9 1.0 0.4 1.1 0.3 0.4 0.4 1.8 1.5 1.6 1.0 0.6
Time employed in main current job 1.2 1.3 5.2 -1.2 -2.3 -2.2 -2.0 -0.4 -1.3 -1.5 -1.3 0.6 -1.8 -1.0 -1.8 -1.9 0.0 0.5 -0.9 -1.2 -0.8 -1.1 -0.2 0.2 0.2 0.1 -1.5 0.1 -0.4 -0.6 -0.5 -0.0 0.0
Alcohol intake versus 10 years previously 0.2 0.3 1.2 -1.1 -0.7 -0.4 -0.3 -0.7 0.3 0.1 -0.1 0.2 -0.8 -0.2 -0.7 -0.7 0.4 0.0 0.1 -0.1 -0.4 0.0 0.1 0.6 0.6 0.7 -0.9 0.0 0.4 0.2 0.2 0.8 0.4
Father’s age at death 3.1 4.1 12.1 -2.2 -2.0 -2.1 -3.5 -0.5 -2.7 -2.9 -2.8 -1.9 -2.1 -2.0 -2.1 -2.1 -0.5 2.3 -2.7 -2.1 -2.0 -1.2 -0.6 -0.8 -1.2 -1.1 -1.1 -2.1 -2.8 -1.8 -2.7 -1.5 -1.7
Worrier / anxious feelings 1.5 2.8 8.4 -0.6 -0.2 -0.0 -0.9 0.6 -1.5 -1.9 -1.8 -0.6 -0.3 -0.3 -0.9 -0.4 0.5 2.4 -2.3 -0.3 -0.9 0.5 -1.6 -2.1 -2.6 -2.3 0.4 -2.5 -2.6 -2.5 -2.6 -2.9 -2.5
Frequency of tiredness / lethargy in last 2 weeks 0.6 0.9 5.5 -2.3 -0.1 0.1 -0.7 0.1 0.0 -0.5 -0.8 1.3 -0.8 0.1 -0.5 -0.5 0.3 1.0 -0.9 0.2 -2.4 0.2 -1.3 -0.6 -1.0 -0.5 -0.5 -1.2 -0.5 -1.7 -0.8 -1.0 -1.0
Falls in the last year 1.1 1.5 5.3 -0.8 1.2 1.4 0.1 1.5 0.6 0.3 -0.0 -0.9 0.9 0.4 0.5 0.9 -0.1 0.7 -0.8 0.6 -0.4 1.1 -1.9 -2.1 -1.9 -1.8 1.1 -2.3 -0.6 -1.8 -0.7 -2.0 -2.0
Hair/balding pattern: Pattern 3 0.2 0.3 1.7 0.8 0.4 0.7 -0.2 0.4 0.1 0.3 0.4 0.4 0.6 0.3 1.0 0.6 0.2 -0.3 0.5 0.6 0.7 0.3 1.3 -0.3 0.4 -0.4 0.9 -0.6 0.1 1.1 0.3 0.1 -0.1
Number of live births 0.6 0.8 2.8 -1.2 -0.6 -0.1 -0.5 0.1 -0.5 -0.8 -1.1 -1.2 -0.9 -1.0 -0.9 -0.8 -0.6 1.3 -1.7 -0.1 -1.6 -0.1 -0.5 -1.1 -0.8 -0.9 -0.3 -0.7 -1.1 -0.6 -0.8 -1.2 -1.2
Forced expiratory volume in 1-second (FEV1) 0.7 2.2 7.1 -1.5 -2.1 -1.2 -0.7 -2.2 -0.7 -1.0 -0.5 1.5 -1.4 -1.6 -1.1 -1.5 -2.7 -0.8 0.6 -1.9 -2.1 -2.6 0.6 2.0 1.1 1.9 -1.6 1.7 0.3 -0.7 0.3 1.0 1.5
Pulse rate 2.7 4.5 14.3 1.0 -0.9 -1.2 0.7 -1.5 0.8 0.8 1.9 2.4 0.1 1.8 0.8 0.0 1.6 -2.9 2.8 -0.5 0.2 -1.8 2.2 3.7 3.1 3.5 -0.9 3.3 1.6 2.6 2.2 3.6 3.8
Happiness 0.6 0.8 2.5 -0.4 0.1 -0.3 1.6 0.7 -0.6 -0.5 -0.7 -0.3 -0.1 -0.2 -0.5 -0.2 0.5 0.7 -1.0 -0.4 0.3 0.1 -0.9 -1.2 -1.4 -1.2 0.5 -1.6 -1.4 -1.1 -1.0 -1.6 -1.3
Noisy workplace 0.5 0.6 2.6 -0.3 0.6 1.0 1.6 0.6 1.0 1.1 1.0 0.3 0.8 1.0 0.5 0.7 1.1 -0.4 0.9 0.6 0.1 1.2 0.1 0.6 0.5 0.8 -0.1 -0.3 0.8 0.3 0.4 0.9 0.2
Qualifications: A levels/AS levels or equivalent 1.3 2.9 9.2 -0.4 -2.5 -1.8 -1.4 -2.1 -2.9 -2.7 -1.9 -1.4 -2.2 -2.1 -2.0 -2.4 -1.7 0.8 -1.2 -3.0 -1.6 -1.9 0.3 0.4 -0.0 0.4 -1.6 0.5 -1.8 -0.9 -1.4 -0.5 0.0
Serious illness, injury or assault of a close relative in last 2 years 0.8 1.0 2.8 -1.7 -0.7 -0.9 -0.5 -0.4 -0.5 -0.8 -1.3 -1.4 -1.2 -1.6 -0.9 -1.0 -1.2 1.2 -1.5 -0.5 -1.3 -0.6 -0.3 -0.7 -0.2 -0.5 -0.8 -1.4 -0.6 -0.9 -0.7 -0.7 -1.0
Mouth/teeth dental problems: Dentures 1.3 2.2 6.1 -0.4 1.2 2.5 0.3 1.4 2.5 2.3 1.8 1.8 1.4 1.4 1.4 1.7 -0.2 -1.3 1.4 2.4 0.4 1.2 0.3 0.7 1.3 0.9 0.2 0.4 2.2 1.4 1.9 1.6 1.1
Asthma 0.6 1.2 5.8 -0.7 -1.0 -0.6 -0.9 -1.5 0.4 -0.0 -0.0 1.1 -1.1 0.2 -0.6 -0.9 0.0 -1.2 0.6 -0.2 -0.1 -2.4 0.4 1.4 1.8 1.4 -1.6 0.1 1.6 0.5 1.4 1.8 1.4
Medication: Ibuprofen (e.g. Nurofen) 0.8 1.0 4.5 0.3 1.8 1.2 1.4 2.1 0.9 1.2 0.9 -0.8 1.2 1.3 1.0 1.2 1.6 -0.4 0.1 1.3 0.6 1.1 0.4 -0.7 -0.0 -0.9 0.9 -0.7 0.5 0.5 0.7 -0.5 -0.4
Medication: Cholesterol lowering 0.2 0.4 1.2 -0.5 0.5 0.9 1.1 0.5 1.0 0.9 0.3 0.8 0.2 1.1 0.2 0.4 0.2 0.2 0.1 1.1 0.3 0.7 0.1 -0.4 0.0 -0.5 0.4 -1.1 0.3 0.7 0.2 0.2 -0.4
Depression (self-reported) 0.3 0.3 2.4 -0.6 0.3 1.1 1.1 0.5 0.8 0.8 0.5 1.0 0.2 0.5 -0.0 0.2 -1.6 -0.4 0.3 0.3 -0.5 0.2 -0.3 0.0 0.1 0.0 -0.1 -0.3 0.7 -0.7 0.5 -0.2 -0.0
Medication: Lansoprazole 1.6 1.8 5.9 1.6 1.5 1.9 1.6 1.9 1.1 1.6 1.5 0.1 1.8 1.6 1.5 1.8 1.5 -0.8 1.1 1.6 2.4 1.4 1.4 -0.0 0.7 -0.1 1.2 -0.8 0.8 1.5 0.9 0.7 0.2
Prospective memory result 0.3 0.4 2.2 -0.3 0.6 0.9 1.5 -0.2 1.0 1.1 0.3 -0.1 0.4 0.8 0.4 0.4 0.8 -0.1 0.1 0.6 -0.2 0.6 -1.4 -0.5 -0.8 -0.5 0.8 0.1 -0.2 0.0 0.3 -0.5 -0.2
Lung cancer (father) 0.4 0.5 2.7 0.0 0.5 0.2 -0.7 0.3 1.1 0.9 0.5 0.4 0.3 0.6 0.4 0.5 1.0 -0.1 0.5 1.1 1.3 0.4 0.5 -0.0 0.7 -0.1 -0.3 -0.2 1.6 0.6 0.8 0.7 0.1
Illnesses of mother 0.6 0.8 3.5 0.0 1.0 1.9 0.7 0.1 1.5 1.5 1.1 -0.0 1.1 1.1 0.9 1.1 -0.8 -0.2 0.8 1.4 0.1 1.7 -0.4 0.0 0.1 0.1 0.4 0.0 0.9 0.2 0.6 0.5 0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 2.9 8.5 -1.6 -2.7 -1.5 -1.3 -2.1 -1.0 -1.4 -0.8 1.2 -2.1 -1.8 -1.7 -2.1 -2.9 -0.7 0.3 -2.1 -2.1 -2.8 0.5 2.2 1.3 2.2 -2.2 1.6 0.1 -0.6 0.2 1.1 1.6
Pulse wave Arterial Stiffness index 0.9 1.0 2.7 0.8 1.6 1.0 0.7 0.5 1.2 1.4 1.3 1.3 1.3 1.6 1.5 1.4 0.9 -0.9 1.0 1.2 1.1 0.9 -0.0 -0.1 0.3 0.1 1.1 -0.7 0.9 0.7 0.8 0.5 0.1
Impedance of arm (left) 0.5 2.3 11.4 3.4 1.2 -0.1 0.6 2.9 -0.0 0.8 1.3 1.5 1.9 1.5 1.8 1.8 1.9 -0.9 1.2 1.0 2.4 0.4 2.4 -0.3 0.9 -0.4 1.8 0.6 0.2 2.3 0.8 0.7 0.7
Arm fat mass (right) 0.6 2.6 6.8 0.3 2.5 2.6 0.9 0.5 2.5 2.3 2.0 1.7 1.9 1.4 2.0 2.0 0.0 -1.6 1.7 2.2 1.3 1.6 1.0 -0.1 1.0 -0.2 1.5 -0.2 2.3 2.0 2.1 1.0 0.3
Trunk predicted mass 0.3 1.5 5.6 -2.1 -0.5 0.6 -0.0 -2.4 1.0 0.5 0.3 1.3 -0.8 -0.7 -0.4 -0.7 -2.0 -1.4 1.0 -0.5 -1.5 -1.6 0.2 1.3 1.2 1.4 -1.2 1.3 1.9 0.2 1.6 1.1 1.2
Standing height 0.2 2.0 8.6 0.0 -0.9 -0.4 -0.3 -0.9 0.1 0.2 0.5 2.9 -0.4 -0.5 -0.0 -0.4 -1.8 -1.8 1.4 -1.0 -0.6 -2.3 2.3 1.4 2.0 1.4 -0.8 1.8 1.8 1.6 2.0 1.6 1.9
Length of working week for main job 0.5 0.5 6.8 0.1 -0.0 -0.3 -1.0 -0.1 -0.5 -0.2 -0.0 1.0 0.3 -1.7 0.6 0.3 -2.6 0.1 -0.1 -0.2 1.2 0.4 0.1 -0.3 -0.1 -0.3 0.5 -0.3 -0.3 0.1 -0.3 -0.2 -0.4
Exposure to tobacco smoke at home 1.0 1.1 3.9 0.0 1.6 1.8 1.0 0.7 2.0 1.6 0.9 -0.2 1.3 0.9 1.1 1.5 -0.4 0.1 0.4 1.9 0.1 1.3 -0.7 -1.0 -0.5 -1.0 1.1 -0.7 0.9 0.2 0.6 -0.3 -0.8
Breastfed as a baby 0.9 1.1 5.3 2.3 0.7 0.2 0.3 1.5 -0.3 0.1 0.2 -2.2 1.3 0.2 0.9 1.1 0.1 0.3 -0.3 0.5 1.8 0.6 -0.5 -1.3 -1.3 -1.2 1.6 0.1 -1.2 -0.1 -0.7 -1.2 -0.6
Tense / ‘highly strung’ 0.3 0.5 3.3 -0.4 -0.3 -0.5 0.3 -0.4 -0.5 -0.6 -0.8 -0.6 -0.5 0.3 -0.5 -0.5 -0.9 0.6 -0.6 -0.2 -0.4 0.1 -1.8 -0.9 -1.2 -0.8 -0.0 -1.1 -0.6 -1.1 -0.8 -0.9 -0.8
Seen doctor (GP) for nerves, anxiety, tension or depression 1.3 2.0 5.0 -0.5 0.1 -0.1 -1.7 1.2 -0.7 -1.0 -1.3 -1.2 0.0 -0.8 -0.2 0.1 -1.5 2.2 -1.8 0.4 -0.4 1.7 -1.5 -2.2 -2.0 -2.2 0.7 -1.9 -1.5 -1.4 -1.8 -2.0 -2.1
Hair/balding pattern: Pattern 4 1.0 2.4 7.6 1.0 -0.1 -0.5 0.9 -1.3 0.7 0.9 1.4 1.6 0.0 1.1 0.2 -0.0 0.3 -2.3 1.6 -0.0 0.3 -1.6 1.2 2.6 2.4 2.5 -0.9 2.5 1.6 1.9 1.9 2.6 2.8
Birth weight of first child 0.5 0.9 2.4 0.0 -0.5 -0.3 -0.5 0.1 -1.0 -1.1 -1.2 -1.1 -0.4 -1.1 -0.9 -0.5 -0.8 1.5 -1.3 -0.6 0.3 0.5 -0.9 -1.1 -1.5 -1.0 -0.2 -0.1 -1.5 -1.1 -1.6 -1.3 -1.0
Peak expiratory flow (PEF) 0.5 1.1 4.6 -0.6 -1.4 -1.5 -1.8 -1.4 -1.2 -1.3 -1.0 -0.2 -0.9 -1.9 -0.9 -1.0 -2.2 0.4 -0.7 -1.6 -1.1 -1.4 -0.1 0.2 -0.2 0.0 -0.5 0.2 -1.0 -0.8 -0.7 -0.4 -0.1
Pulse wave reflection index 1.2 1.5 6.3 -0.6 1.3 0.8 0.0 1.3 0.4 0.5 -0.3 -1.0 0.6 -0.0 0.5 0.7 -0.4 1.1 -1.0 1.0 0.8 1.6 -1.5 -2.1 -1.7 -1.9 1.0 -2.5 -0.4 -1.5 -0.8 -1.9 -2.2
Ever highly irritable/argumentative for 2 days 1.8 2.1 6.2 0.7 1.8 2.3 1.7 2.3 0.7 1.0 0.8 1.2 1.8 1.3 1.5 1.7 1.0 0.4 0.4 1.6 2.0 2.5 -0.1 -1.7 -1.5 -1.7 2.0 -1.4 -0.3 -0.4 -0.4 -1.5 -1.6
Loud music exposure frequency 0.8 0.9 3.6 0.1 -1.6 -1.4 -0.5 -0.6 -1.9 -1.3 -0.8 1.6 -0.6 -1.2 -1.0 -0.9 0.7 0.4 -0.3 -1.6 0.2 -0.7 0.8 0.6 0.1 0.6 -0.9 -0.3 -1.2 -0.6 -1.1 -0.2 -0.1
Qualifications: O levels/GCSEs or equivalent 0.2 0.4 2.3 0.7 -0.1 -0.7 -0.4 -1.3 -0.9 -0.8 -0.2 -0.1 -0.5 -0.7 -0.0 -0.5 -1.5 -0.3 0.4 -0.6 -0.7 -0.5 0.5 0.7 0.5 0.8 -0.5 0.5 -0.1 0.1 -0.0 0.5 0.6
Mouth/teeth dental problems: Bleeding gums 2.1 2.8 7.5 -0.2 -1.1 -1.8 0.3 -2.0 -0.2 -0.2 0.5 1.6 -1.4 -0.2 -0.8 -1.4 -0.0 -2.0 1.8 -1.3 -0.7 -2.4 1.8 2.7 2.5 2.7 -1.9 2.4 1.9 0.6 1.6 2.3 2.6
Blood clot in the leg (DVT) 0.7 0.8 3.1 1.5 0.4 0.8 0.2 1.3 0.1 0.2 0.2 -0.6 0.9 0.8 0.5 0.8 1.4 0.5 -0.1 0.6 1.3 1.2 -0.3 -1.3 -1.2 -1.2 1.8 0.3 -1.3 0.6 -0.6 -1.0 -0.7
Medication: Paracetamol 0.5 0.8 3.1 0.4 1.0 1.2 0.1 1.5 0.3 0.1 -0.0 -1.0 0.9 0.0 0.7 1.0 -0.7 0.8 -0.5 1.3 -0.0 1.3 0.7 -1.3 -0.5 -1.2 0.9 -1.8 -0.5 0.4 -0.5 -0.6 -1.1
Headache pain in last month 2.0 3.4 12.2 0.2 3.0 3.0 1.4 2.6 3.0 2.5 1.8 -0.2 2.1 2.6 2.4 2.5 2.0 -0.2 0.7 3.5 0.5 2.4 -0.0 -1.1 -0.1 -1.1 1.8 -1.5 1.2 0.9 1.0 0.1 -0.6
Medication for cholesterol, blood pressure or diabetes 0.9 1.4 6.5 0.3 -0.4 -0.8 -0.8 -0.2 -1.4 -1.2 -1.3 -2.5 -0.5 -1.5 -0.7 -0.6 -0.2 1.3 -1.4 -0.9 -0.4 0.2 -1.8 -1.0 -1.8 -0.9 0.1 0.1 -1.7 -1.9 -1.6 -1.7 -1.0
Glaucoma (self-reported) 0.4 0.5 1.5 -1.2 -1.1 -0.4 -0.9 -0.7 -0.7 -0.8 -0.6 0.7 -0.9 -0.2 -0.9 -0.9 -1.2 0.3 -0.2 -0.8 -1.1 -0.4 0.6 0.1 0.2 0.1 -0.7 -0.2 0.1 -0.3 -0.2 0.1 -0.2
Gout (self-reported) 0.1 0.1 0.9 -0.2 -0.2 0.5 0.3 -1.0 -0.3 -0.2 -0.1 0.1 -0.4 -0.4 -0.3 -0.3 -0.4 -0.3 0.1 -0.0 -0.8 -0.1 0.2 0.7 0.4 0.6 -0.5 -0.2 0.2 -0.1 0.1 0.3 0.1
Hypothyroidism/myxoedema (self-reported) 1.6 3.0 12.7 0.5 0.1 0.8 -0.1 -0.2 0.9 1.3 1.9 1.7 0.8 1.4 1.1 0.8 1.3 -2.2 2.6 0.5 0.1 -0.7 3.6 2.4 3.1 2.3 -0.1 0.4 1.9 2.6 2.0 3.0 2.2
Medication: Amlodipine 1.6 2.3 5.8 0.9 2.3 1.9 1.8 1.8 1.8 1.7 1.5 1.3 2.4 1.4 2.2 2.4 -1.1 -0.8 0.8 2.0 1.5 1.9 -1.2 -1.1 -0.9 -1.1 2.4 -0.6 0.4 0.6 0.5 -0.4 -0.6
Medication: Ventolin 100micrograms inhaler 0.3 0.3 3.1 -0.6 -0.2 -0.7 0.2 -0.7 0.2 -0.2 -0.5 -0.4 -0.8 0.0 -0.5 -0.7 -0.7 0.0 -0.5 -0.1 -0.1 -1.3 -1.8 -0.1 -0.6 0.1 -0.4 -0.3 -0.2 -0.8 -0.1 -0.3 -0.2
Birth weight 0.4 0.9 2.3 0.3 -0.5 -1.0 -1.5 0.6 -1.5 -1.5 -1.0 0.2 -0.2 -1.4 -0.3 -0.3 -1.5 0.6 -0.6 -1.2 -0.2 -0.0 -0.6 -0.8 -1.4 -0.9 0.5 0.3 -1.3 -0.9 -1.2 -1.2 -0.6
Chronic bronchitis/emphysema (mother) 0.3 0.3 1.3 -0.2 0.3 -0.6 -1.1 0.6 0.3 -0.1 -0.1 1.1 0.1 -0.3 0.2 0.2 0.1 -0.2 -0.2 0.0 0.4 -0.8 -0.4 -1.0 -0.6 -1.0 0.8 -0.9 -0.2 0.3 0.2 -0.7 -0.6
High blood pressure (siblings) 1.3 1.8 5.5 -0.3 -0.8 -1.0 -0.4 1.0 -1.5 -1.5 -1.4 -1.1 -0.8 -0.9 -1.2 -0.9 -0.8 1.6 -1.9 -1.3 -0.4 -0.0 -1.1 -1.4 -1.5 -1.5 0.1 -2.4 -2.2 -1.6 -1.9 -1.8 -1.9
Forced vital capacity (FVC), Best measure 0.4 1.6 6.3 -1.6 -2.4 -1.3 -1.2 -1.0 -0.9 -1.2 -1.0 0.6 -1.8 -1.6 -1.5 -1.8 -2.5 0.0 -0.4 -1.5 -1.6 -1.9 -0.2 1.0 0.4 1.0 -1.6 0.4 -0.5 -0.9 -0.3 0.2 0.5
Body fat percentage 1.0 4.1 10.8 1.5 3.3 2.8 0.9 2.0 2.4 2.4 2.1 1.8 2.8 2.0 2.7 2.9 0.8 -1.1 1.4 2.9 2.7 2.7 1.2 -1.0 0.4 -1.2 2.7 -1.0 1.6 2.4 1.5 0.5 -0.4
Leg fat percentage (right) 1.1 4.1 11.6 1.3 3.4 3.0 1.1 2.0 2.4 2.3 1.8 0.7 2.8 1.8 2.5 2.9 1.1 -0.3 0.7 3.1 2.7 3.1 0.7 -1.8 -0.1 -1.9 2.9 -2.0 1.0 2.2 1.0 -0.1 -1.3
Arm fat-free mass (right) 0.2 0.9 4.5 -2.1 -0.3 1.0 0.0 -2.1 1.0 0.4 0.0 0.9 -0.8 -0.6 -0.6 -0.6 -2.1 -0.8 0.3 -0.1 -1.7 -0.6 -0.4 0.8 0.5 0.8 -1.0 0.5 1.4 -0.4 1.1 0.5 0.4
Exposure to tobacco smoke outside home 3.9 5.2 10.7 1.4 2.0 2.4 1.9 0.3 2.7 2.9 3.0 3.3 2.2 1.7 2.6 2.3 -1.4 -3.1 3.2 1.9 0.8 0.1 1.8 1.9 2.6 1.9 1.1 1.4 3.1 2.7 3.1 2.8 2.3
Comparative body size at age 10 0.2 0.7 3.2 -0.4 -0.4 0.2 0.5 -1.3 1.0 0.4 0.5 0.4 -0.5 0.4 0.0 -0.4 -0.5 -1.0 1.1 0.6 0.1 -1.2 -0.5 1.3 0.4 1.2 -0.2 1.8 0.6 0.5 0.8 1.0 1.5
Number of full brothers 0.3 0.3 1.3 0.4 1.0 1.1 0.2 0.3 0.4 0.5 0.5 -0.2 1.1 -0.1 1.0 1.1 -0.6 -0.3 0.5 0.6 -0.2 1.0 0.4 -0.0 0.1 -0.1 0.7 -0.5 0.5 0.2 0.2 0.1 -0.0
Worry too long after embarrassment 0.4 0.6 3.8 -0.9 -0.2 -0.0 -0.4 -0.7 -0.6 -1.0 -0.9 1.0 -0.4 -0.7 -0.4 -0.4 -1.9 0.2 -0.7 -0.8 -1.5 -1.1 -0.9 -0.3 -0.8 -0.3 -0.2 -0.2 -0.6 -1.1 -0.5 -0.9 -0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 3.7 -0.0 0.0 0.3 0.3 0.1 0.5 0.5 0.5 1.2 0.1 0.4 0.2 0.1 -1.9 -0.8 0.6 0.4 0.3 -0.5 0.1 0.6 0.6 0.5 -0.3 0.6 0.9 -0.0 0.8 0.6 0.8
Wheeze or whistling in the chest in last year 1.3 2.3 6.7 -1.5 -2.2 -1.9 -1.5 -1.4 -1.8 -1.7 -1.6 1.2 -2.5 -1.8 -1.9 -2.3 -1.6 0.6 -0.8 -1.4 -1.1 -2.0 1.0 1.3 1.2 1.2 -2.6 -0.5 -0.2 -0.9 -0.7 0.8 0.5
Number of children fathered 0.6 0.7 2.9 -0.2 0.2 -0.9 -1.0 -0.5 -0.9 -0.9 -1.0 0.5 -0.3 -1.3 -0.3 -0.2 -0.9 1.7 -1.0 -0.1 -0.1 0.7 -0.1 -1.0 -1.0 -0.9 -0.1 -0.7 -1.1 -0.8 -1.6 -0.8 -1.1
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.3 1.4 -0.2 -0.9 -1.1 -0.4 -0.1 -0.7 -0.6 -0.5 -0.7 -0.5 -0.7 -0.4 -0.6 -0.6 0.1 -0.5 -0.8 -0.2 -1.2 -0.6 0.0 -0.1 0.3 -0.3 -1.0 -0.8 -0.3 -0.5 0.0 -0.2
Age at first live birth 2.3 4.0 13.9 -0.7 -2.7 -2.8 -2.0 -2.6 -3.1 -2.9 -2.4 -0.5 -2.7 -2.3 -2.6 -2.9 -0.6 1.2 -1.5 -3.7 -1.7 -2.7 0.1 0.7 -0.3 0.7 -2.0 0.7 -1.8 -1.6 -1.7 -0.6 0.1
Pulse wave peak to peak time 0.9 1.0 3.2 -0.9 -1.8 -1.1 -0.5 -0.7 -1.0 -1.3 -1.2 -0.9 -1.4 -1.6 -1.6 -1.5 -1.1 0.6 -0.8 -1.2 -1.3 -1.1 0.1 0.4 0.0 0.2 -1.3 1.0 -0.6 -0.5 -0.5 -0.1 0.2
Health satisfaction 1.0 1.3 3.9 -1.4 1.6 1.5 0.7 1.1 0.9 0.7 -0.1 -0.8 0.5 0.5 0.3 0.7 0.4 0.8 -0.9 1.3 -0.3 1.6 -1.5 -1.7 -1.4 -1.6 0.6 -2.0 -0.2 -1.2 -0.5 -1.5 -1.7
Shortness of breath walking on level ground 0.2 0.2 1.0 -0.6 -0.4 0.6 0.1 0.4 -0.7 -0.5 -0.5 0.9 -0.1 -0.3 -0.3 -0.2 0.0 0.6 -0.1 -0.4 0.1 0.4 1.0 -0.4 -0.3 -0.3 -0.2 -0.2 -0.4 -0.2 -0.6 -0.5 -0.6
Qualifications: College or University degree 0.9 2.7 7.0 -1.4 -2.6 -1.9 -1.2 -1.4 -2.3 -2.2 -1.8 -0.9 -2.2 -2.0 -2.0 -2.3 -1.7 0.8 -1.2 -2.2 -2.4 -1.6 -0.5 0.9 -0.2 0.8 -2.2 1.1 -1.3 -1.8 -1.3 -0.4 0.3
Eye problems/disorders: None of the above 0.3 0.4 2.1 0.9 -0.5 -1.4 0.5 -1.0 -0.1 0.0 -0.2 -1.1 -0.7 -0.1 -0.5 -0.6 -0.3 0.2 -0.3 -0.1 0.7 -0.2 -0.7 0.6 0.1 0.6 -0.4 1.2 -0.5 0.4 -0.2 0.6 0.9
Mouth/teeth dental problems: Loose teeth 0.8 0.9 2.5 -0.6 -0.3 -1.1 -1.3 -0.1 -1.0 -1.1 -1.2 -1.1 -1.0 -1.4 -1.0 -1.0 -0.0 1.4 -1.1 -0.5 -0.8 0.2 -0.7 -0.7 -0.9 -0.6 -0.7 -0.7 -0.8 -1.6 -1.2 -1.0 -0.9
Emphysema/chronic bronchitis 0.5 0.6 2.3 0.6 -0.8 -0.9 0.3 -0.1 -0.5 -0.1 0.3 0.7 -0.2 -0.3 -0.2 -0.3 -0.3 -0.8 0.6 -0.8 1.5 -0.9 1.4 1.2 1.3 1.2 -0.8 0.5 0.6 0.6 0.6 1.0 1.0
Medication for pain relief, constipation, heartburn 1.4 2.4 6.8 -1.3 -1.9 -1.9 -2.0 -2.5 -1.7 -1.7 -1.4 -0.3 -1.9 -1.6 -2.0 -2.0 -2.1 0.7 -0.8 -2.6 -1.5 -1.0 -1.7 0.6 -0.8 0.7 -1.5 0.8 -1.0 -2.1 -1.2 -0.5 0.1
Neck or shoulder pain in last month 1.7 2.4 5.8 -2.4 -0.3 -0.6 -1.2 0.9 -1.0 -1.6 -1.9 0.2 -1.1 -1.1 -0.9 -0.9 -0.7 2.1 -2.1 -0.3 -1.9 0.7 -1.9 -1.9 -2.2 -1.9 -0.2 -1.5 -1.7 -2.3 -2.0 -2.1 -2.1
Medication: Blood pressure 1.2 2.2 8.7 0.5 0.4 0.5 0.5 -0.1 0.9 0.9 1.5 2.9 0.7 1.2 1.0 0.7 0.0 -1.8 2.0 0.4 0.8 -0.7 2.7 1.6 2.4 1.6 -0.1 0.3 1.8 2.4 1.7 2.4 1.6
Angina (self-reported) 1.8 2.4 4.6 -0.8 -2.1 -1.9 -0.8 0.2 -2.1 -1.8 -2.0 -1.0 -1.9 -1.6 -2.0 -2.0 -0.2 2.0 -2.1 -1.6 -1.7 0.0 -0.4 -0.9 -1.2 -0.9 -1.1 -0.6 -2.1 -1.6 -2.1 -1.6 -1.4
Migraine (self-reported) 1.6 1.9 6.6 2.6 1.6 1.5 1.9 0.9 1.1 1.3 1.8 0.5 1.6 1.3 2.1 1.6 0.1 -2.1 1.7 0.6 1.4 -1.0 1.3 0.6 0.8 0.4 1.5 1.2 1.1 1.1 1.6 0.6 1.3
Medication: Ibuprofen 1.4 1.7 6.6 -0.1 2.2 1.7 1.3 2.6 1.5 1.6 1.0 -0.6 1.6 1.8 1.2 1.6 1.8 -0.3 -0.1 1.8 1.0 1.6 -0.3 -1.2 -0.5 -1.4 1.4 -1.1 0.4 0.5 0.8 -0.7 -0.8
Medication: Allopurinol 0.3 0.4 1.2 -0.6 -0.7 0.2 -0.4 -0.6 -0.8 -0.9 -0.9 -0.4 -0.7 -1.1 -0.7 -0.7 -0.5 0.6 -0.7 -0.6 -1.1 -0.1 -0.3 -0.4 -0.5 -0.4 -0.3 -0.6 -0.5 -0.5 -0.6 -0.6 -0.7
Medication: Omeprazole 0.8 1.0 3.4 0.2 0.6 0.5 0.3 1.0 0.0 -0.2 -0.7 -1.4 -0.1 -0.3 0.2 0.1 0.3 1.3 -1.4 0.8 0.3 0.8 -1.0 -1.8 -1.4 -1.8 0.9 -1.5 -1.3 -0.1 -0.9 -1.5 -1.5
Medication: Seretide 50 evohaler 0.3 0.3 1.3 -0.0 -0.3 -0.6 -0.2 0.4 -0.6 -0.6 -0.4 -0.9 -0.5 -0.0 -0.4 -0.5 1.1 0.0 -0.7 -0.5 0.1 -0.8 -0.6 -0.3 -0.2 -0.1 -0.1 -1.1 -0.7 -0.9 -0.4 -0.6 -0.6
Mean time to correctly identify matches 0.2 0.4 2.3 -0.0 -1.2 -0.3 0.4 -1.5 -0.3 -0.3 -0.4 0.7 -0.9 0.6 -1.0 -0.9 0.8 0.2 -0.0 -0.3 0.0 -0.7 -0.5 0.5 0.2 0.4 -0.3 0.2 -0.6 0.6 -0.4 0.7 0.4
Heart disease (mother) 0.1 0.2 2.2 0.7 -0.2 -0.2 0.5 0.6 -0.5 -0.5 -0.0 0.0 0.1 0.1 0.3 0.0 0.1 -0.1 0.3 0.0 0.1 -0.1 1.5 -0.0 0.5 0.0 0.1 0.1 0.1 0.6 0.2 0.1 0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.3 1.6 7.7 0.1 -1.0 -1.8 -1.6 -2.4 -1.1 -1.0 -0.6 -0.1 -1.1 -1.7 -0.7 -1.1 -0.8 -0.8 -0.0 -1.8 0.1 -2.8 1.0 1.4 1.3 1.3 -1.4 1.6 0.3 0.3 0.5 0.9 1.5
Whole body fat mass 0.7 3.1 7.3 0.7 2.7 2.7 0.8 1.1 2.4 2.3 2.0 2.1 2.2 1.6 2.3 2.3 0.2 -1.4 1.6 2.5 1.9 1.9 1.4 -0.4 0.9 -0.6 1.9 -0.4 2.1 2.2 1.9 0.8 0.0
Leg fat mass (right) 0.6 2.1 6.8 0.0 2.4 2.6 0.7 0.6 2.2 1.9 1.5 1.5 1.8 1.2 1.7 1.9 0.1 -0.9 0.9 2.2 1.3 1.9 0.9 -0.7 0.6 -0.8 1.5 -1.1 1.8 1.8 1.5 0.5 -0.4
Arm predicted mass (right) 0.2 0.9 4.9 -2.2 -0.4 0.9 -0.0 -2.2 0.9 0.3 -0.1 0.9 -0.9 -0.7 -0.7 -0.7 -1.9 -0.7 0.2 -0.3 -1.6 -0.7 -0.6 0.8 0.4 0.8 -1.1 0.6 1.3 -0.5 0.9 0.4 0.4
Pulse rate, automated reading 1.2 3.7 12.7 2.0 -0.9 -1.4 1.0 -0.9 0.9 0.9 1.8 1.9 0.8 2.6 1.4 0.7 3.3 -2.3 2.5 0.0 1.8 -0.5 1.5 2.1 2.1 2.1 0.7 2.9 1.1 3.6 1.8 3.1 3.0
Alcohol intake frequency. 1.0 2.4 12.2 0.4 1.4 1.8 1.2 0.9 1.8 1.9 1.8 3.5 1.5 1.4 1.7 1.6 0.2 -1.6 1.8 1.2 1.0 0.2 2.2 0.7 1.7 0.7 0.5 0.2 2.2 1.8 2.0 1.4 1.1
Comparative height size at age 10 0.2 0.9 2.7 -1.6 -1.0 -1.0 -0.8 -0.4 -0.7 -1.1 -1.1 1.1 -1.6 -0.6 -1.4 -1.6 -1.5 0.2 -0.5 -1.4 -1.3 -1.5 -0.5 -0.2 -0.3 -0.2 -0.9 0.1 0.1 -0.5 -0.0 -0.4 -0.2
Number of full sisters 0.9 1.1 2.8 0.9 1.7 1.3 1.7 1.1 1.2 1.3 0.9 -0.7 1.5 0.8 1.5 1.6 1.5 -0.3 0.2 1.2 1.4 0.3 0.1 -1.0 -0.2 -0.9 1.4 -1.1 0.3 0.6 0.7 -0.4 -0.6
Suffer from ‘nerves’ 0.3 0.4 3.3 -0.5 -0.4 -0.8 -0.6 -1.1 -0.0 -0.4 -0.2 0.9 -0.5 0.5 -0.7 -0.5 -0.1 -0.6 0.2 -0.4 -1.0 -1.8 -0.3 0.7 0.5 0.6 -1.0 -0.3 0.5 -0.6 0.5 0.4 0.6
Overall health rating 0.3 0.6 3.7 -1.9 0.8 0.9 -0.1 0.3 1.0 0.4 -0.2 0.9 -0.1 0.3 -0.1 0.1 0.2 0.5 -0.6 0.7 -1.1 0.4 -1.3 -0.9 -0.7 -0.9 0.2 -1.7 -0.2 -0.3 -0.2 -0.6 -1.0
Chest pain or discomfort 0.7 1.1 3.8 -0.5 -0.8 -0.7 -0.5 0.1 -1.9 -1.7 -1.4 0.2 -0.9 -1.4 -0.8 -1.0 -1.6 0.9 -0.8 -1.3 -0.7 -0.6 0.5 -0.6 -0.8 -0.5 -0.5 -0.9 -0.9 -1.8 -1.4 -1.2 -1.0
Had major operations 0.9 1.1 4.5 -0.7 -1.4 -1.1 0.7 -1.3 -1.1 -1.2 -0.9 -2.1 -1.8 -0.3 -1.4 -1.8 0.7 0.1 -0.6 -1.6 -1.4 -1.3 -0.2 0.1 0.0 0.2 -1.2 0.2 -0.3 -0.9 -0.2 -0.3 -0.1
Age at last live birth 1.8 2.6 6.5 -1.8 -1.8 -1.9 -2.1 -1.8 -2.2 -2.1 -2.1 -0.9 -2.3 -1.9 -2.1 -2.3 0.0 1.4 -1.6 -2.5 -2.0 -1.6 -0.4 -0.0 -0.6 0.2 -1.4 0.2 -1.6 -1.5 -1.4 -0.9 -0.5
Family relationship satisfaction 0.2 0.3 1.4 0.0 0.8 -0.0 1.2 0.6 0.4 0.8 0.7 0.9 0.6 0.6 0.7 0.6 0.6 -0.7 0.6 0.5 0.7 -0.0 0.3 0.0 0.2 -0.0 0.3 -0.1 0.4 0.1 0.5 0.1 0.2
Leg pain on walking 0.3 0.4 2.4 -1.2 0.7 1.6 0.8 0.2 0.7 0.3 0.2 0.3 0.4 1.2 0.1 0.5 0.5 0.2 0.1 0.9 -0.2 0.5 -0.8 -0.3 -1.0 -0.1 0.6 0.5 -0.1 -1.0 -0.2 -0.8 -0.3
Qualifications: NVQ or HND or HNC or equivalent 1.2 1.4 5.9 0.6 -0.7 -0.7 -2.4 -0.7 -1.9 -1.7 -1.3 -1.0 -0.6 -2.0 -0.8 -0.7 -0.7 1.5 -1.1 -1.4 0.9 -0.1 1.1 -0.8 -0.7 -0.7 0.3 -1.3 -1.9 -0.4 -1.7 -1.3 -1.2
Commuting to job workplace: Car/motor vehicle 0.8 0.9 2.2 -0.6 -0.2 -0.6 -1.0 0.7 -0.9 -1.0 -1.0 -0.4 -0.2 -1.4 -0.1 -0.2 -1.0 1.4 -1.3 -0.3 -0.8 0.9 -0.2 -1.2 -1.1 -1.1 0.4 -1.3 -1.5 -0.7 -1.4 -1.3 -1.4
Illness, injury, bereavement, stress in last 2 years 0.6 0.7 2.4 1.5 1.0 0.9 0.1 0.7 0.7 0.8 1.0 0.4 1.1 1.3 0.9 1.0 1.5 -0.5 0.9 0.8 1.1 1.3 0.3 -0.0 0.0 -0.0 0.7 0.9 0.6 0.8 0.5 0.3 0.3
Medication: Aspirin 1.9 2.5 5.8 1.6 1.1 0.7 2.3 0.5 1.7 1.9 1.9 1.0 1.1 1.9 1.5 1.2 2.4 -2.4 1.8 1.3 1.4 -0.7 1.0 1.1 1.9 1.1 0.5 0.6 2.1 1.7 2.3 1.7 1.6
Supplements: Vitamin C 5.0 5.9 15.9 -0.7 -2.7 -3.3 -3.2 -2.0 -4.0 -3.9 -3.2 -1.4 -2.7 -3.3 -2.7 -2.9 -0.7 2.2 -2.5 -3.1 -0.6 -2.0 0.0 -0.5 -1.2 -0.5 -1.4 -1.9 -3.4 -2.5 -3.0 -2.0 -1.3
Knee pain experienced in last month 1.3 2.0 8.4 -2.7 -1.3 -0.7 -0.0 -2.1 0.4 -0.3 -0.5 2.0 -1.9 -0.5 -1.4 -1.5 -0.7 -0.1 0.2 -0.1 -2.9 -1.0 0.4 1.7 1.6 1.9 -2.6 1.0 1.6 0.1 0.8 1.8 1.2
Hypertension (Self-reported) 0.5 1.5 4.2 -0.0 1.4 1.7 0.6 0.7 2.1 1.8 1.3 1.8 1.4 1.9 0.9 1.5 1.3 -0.7 0.7 1.9 1.4 1.0 0.2 -0.1 0.8 -0.2 0.5 -1.3 1.6 1.2 1.2 1.0 0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.3 1.7 1.2 0.5 -0.3 -0.9 0.5 -0.2 -0.2 0.1 0.3 0.5 -0.1 0.5 0.5 1.3 0.1 -0.0 0.3 0.5 -0.2 1.2 -0.2 0.4 -0.1 0.3 -0.5 -0.2 0.9 -0.0 0.2 -0.1
Illnesses of father: Heart disease 0.8 1.1 2.9 1.2 1.0 0.6 1.1 0.3 1.2 1.1 1.4 1.1 1.2 1.5 1.1 1.1 0.6 -1.4 1.5 0.7 0.5 0.2 0.1 0.6 0.6 0.6 0.8 1.5 0.9 1.7 1.2 1.2 1.3
Illnesses of siblings: Diabetes 0.3 0.3 1.8 0.9 0.6 0.8 0.2 0.4 0.1 0.4 0.6 0.3 1.0 0.3 0.8 0.9 -0.4 -0.3 0.3 0.4 1.4 0.9 0.3 0.2 -0.1 -0.1 0.9 -0.6 -0.4 0.4 -0.3 -0.0 -0.2
Smoking status: Previous 1.0 1.5 3.8 1.7 1.8 1.7 0.7 1.0 1.3 1.4 1.5 -0.5 1.8 1.0 1.8 1.8 -0.0 -0.6 1.2 1.9 1.9 0.8 1.3 -0.5 0.4 -0.5 1.7 -0.2 0.8 1.3 0.8 0.5 0.1
Forced expiratory volume in 1-second (FEV1), predicted 1.1 2.3 6.3 1.1 -0.7 0.1 0.6 -1.1 0.1 0.3 1.2 2.1 0.1 0.2 0.3 -0.1 -1.9 -2.4 2.0 -0.7 -0.0 -1.7 2.0 2.2 2.2 2.4 -0.7 2.1 1.4 1.4 1.9 2.0 2.5
Whole body fat-free mass 0.3 1.8 6.2 -2.1 -0.5 0.7 -0.0 -2.5 1.1 0.5 0.4 1.7 -0.8 -0.6 -0.4 -0.7 -2.3 -1.6 1.1 -0.5 -1.6 -1.5 0.3 1.6 1.3 1.6 -1.4 1.6 2.1 0.2 1.8 1.3 1.4
Leg fat-free mass (right) 0.4 1.9 6.1 -2.2 -0.5 0.4 -0.3 -2.5 0.8 0.3 0.3 1.9 -1.0 -0.7 -0.5 -0.9 -2.3 -1.5 1.1 -0.6 -1.8 -1.3 0.4 1.7 1.4 1.8 -1.6 1.8 2.1 -0.1 1.6 1.3 1.5
Arm fat percentage (left) 1.1 4.5 11.2 1.5 3.3 3.0 1.1 1.5 2.8 2.7 2.6 1.6 2.8 2.1 2.8 2.9 1.1 -1.7 2.0 2.9 2.6 2.4 1.3 -0.4 0.9 -0.5 2.4 -0.2 2.2 2.6 2.1 1.1 0.3
Average weekly red wine intake 0.9 1.3 5.0 0.3 -1.7 -1.7 -2.2 -2.1 -1.4 -1.5 -1.0 -1.2 -1.2 -1.6 -0.9 -1.2 -1.1 0.1 0.0 -1.4 0.5 -2.0 0.3 0.7 0.2 0.8 -0.5 0.4 -0.8 0.2 -0.6 0.5 0.6
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.5 -0.8 -0.9 -0.9 -0.0 -0.6 -0.4 -0.6 -0.4 0.6 -1.2 -0.8 -1.0 -1.2 -0.6 -0.0 0.0 -1.0 -0.6 -1.0 -0.7 0.9 0.1 0.9 -1.1 0.7 0.0 -0.8 -0.2 0.4 0.5
Mood swings 0.5 0.8 4.5 -1.5 0.4 0.9 -0.8 -0.5 1.5 0.7 0.7 2.1 0.0 1.4 0.3 0.2 0.6 -0.7 0.9 1.1 -1.3 -0.2 -1.0 0.7 0.2 0.8 -0.5 0.6 1.2 -0.6 0.8 0.7 0.9
Loneliness, isolation 0.6 0.9 4.5 -1.2 1.0 0.6 -0.1 0.3 1.7 1.1 0.9 1.1 0.4 2.1 0.3 0.6 2.0 -0.7 0.5 1.3 -1.2 0.7 -0.5 0.3 0.3 0.2 -0.0 0.3 1.4 0.1 1.1 0.5 0.5
Long-standing illness, disability or infirmity 0.4 0.6 3.6 -1.3 0.1 0.6 0.0 -0.5 0.7 0.5 0.3 1.9 -0.3 0.5 0.2 -0.0 1.0 -0.6 0.7 0.2 0.0 -0.8 0.7 0.7 1.1 0.9 -0.5 -0.4 1.1 0.5 0.9 1.0 0.5
Ever had bowel cancer screening 0.3 0.3 1.4 -0.5 -0.8 0.3 0.9 -0.2 0.3 0.3 0.0 1.2 -0.5 -0.2 -0.6 -0.5 -0.2 -0.5 0.3 -0.0 -0.9 -1.2 0.1 0.6 0.4 0.4 -0.4 0.7 0.3 0.4 0.5 0.5 0.7
Diabetes diagnosed by doctor 0.6 1.0 4.0 0.1 0.9 1.3 0.9 -0.9 0.9 0.9 1.1 2.0 1.0 1.1 0.9 1.0 0.5 -1.4 1.5 0.4 0.2 -0.2 1.2 0.7 1.1 0.7 0.6 -0.4 1.1 1.6 1.3 1.0 0.7
Ever had stillbirth, spontaneous miscarriage or termination 2.0 2.2 8.1 2.1 1.6 1.4 1.6 1.2 0.7 1.6 1.6 0.2 2.2 1.5 2.0 2.0 2.8 -1.1 1.4 1.0 2.7 0.9 1.4 -0.4 0.3 -0.3 2.0 -0.1 0.3 1.8 0.9 0.2 0.1
Friendships satisfaction 0.4 0.5 4.0 0.0 0.9 0.3 2.0 0.9 0.5 0.8 0.6 1.1 0.8 1.1 0.8 0.7 0.9 -0.3 0.1 0.4 1.1 0.2 0.2 -0.3 -0.2 -0.3 0.5 -0.4 -0.0 -0.2 0.1 -0.4 -0.2
Qualifications: nursing, teaching 0.4 0.6 2.4 0.5 -0.2 -0.9 0.1 -0.0 -1.1 -0.8 -0.8 -0.6 -0.6 -0.6 -0.3 -0.6 -1.1 0.8 -0.8 -0.8 0.2 0.2 -1.1 -0.4 -1.0 -0.5 0.2 -0.7 -1.6 -0.7 -1.2 -0.8 -0.6
Commuting to job workplace: Walk 0.3 0.3 1.8 0.8 -0.5 0.1 -0.5 -0.5 -0.6 -0.5 0.2 0.1 -0.1 0.1 -0.0 -0.2 -0.2 -0.7 0.2 -0.8 0.4 -1.3 0.5 0.8 0.4 0.8 -0.3 1.0 -0.3 0.2 0.3 0.1 0.9
Eye problems/disorders: Cataract 0.7 0.8 3.2 -1.5 -0.8 0.7 -1.7 -0.0 -0.7 -0.8 -0.6 -0.1 -0.6 -1.0 -0.9 -0.8 -1.2 0.6 -0.8 -0.5 -1.8 0.1 0.1 -0.6 -0.4 -0.5 -0.7 -1.2 -0.3 -1.1 -0.5 -1.0 -1.0
Mouth/teeth dental problems: Mouth ulcers 0.8 1.2 4.1 0.2 0.0 0.4 1.5 -0.1 0.4 0.6 1.2 0.7 0.1 1.2 0.3 0.0 1.2 -2.0 1.4 -0.1 -0.1 -1.2 1.0 1.6 1.6 1.9 -0.4 1.4 1.1 0.9 1.6 1.4 1.8
Medication for cholesterol 0.2 0.3 1.6 0.7 -0.1 -0.7 -0.6 0.6 -0.5 -0.3 0.2 -1.3 0.1 -0.3 0.5 0.0 -0.0 -0.7 0.4 -0.4 0.3 -0.7 0.8 0.2 0.3 0.1 0.5 1.2 -0.1 0.7 0.4 0.1 0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 2.5 0.3 0.4 1.0 0.6 0.0 1.0 0.9 0.7 0.7 0.8 0.2 0.8 0.9 -0.5 -0.3 0.8 1.5 0.7 0.3 0.8 0.2 0.8 0.1 0.3 -0.1 0.8 1.6 0.8 1.1 0.5
Back pain experienced in last month 1.3 1.9 6.6 -2.1 1.3 1.6 -0.1 1.0 0.7 0.2 -0.6 -0.1 0.4 0.5 -0.1 0.6 0.7 1.8 -1.4 1.6 -0.3 1.8 -1.2 -2.3 -1.8 -2.1 0.5 -2.6 -0.6 -1.5 -1.1 -1.8 -2.5
Mineral and other dietary supplements 0.9 1.2 3.6 1.3 0.8 1.5 1.5 1.9 1.2 1.5 1.6 0.7 1.7 1.5 1.3 1.5 -0.4 -1.0 1.1 0.7 0.6 1.6 0.5 -0.1 0.4 0.1 0.9 -0.3 0.8 0.8 0.9 0.3 0.1
Breast cancer (self-reported) 1.7 2.0 5.4 -1.0 -1.8 -1.6 -0.7 -1.9 -1.8 -1.7 -1.7 -0.5 -2.3 -1.3 -2.3 -2.3 -0.8 0.7 -1.5 -2.2 -1.1 -2.0 -0.5 0.1 -0.5 -0.0 -1.6 0.4 -1.2 -1.8 -0.9 -1.1 -0.3
Asthma (self-reported) 0.8 1.7 6.6 -0.7 -0.9 -0.5 -0.9 -1.7 0.6 0.2 0.3 1.3 -1.0 0.5 -0.5 -0.8 0.2 -1.6 1.0 -0.2 -0.1 -2.6 0.7 1.8 2.2 1.9 -1.7 0.5 2.0 0.8 1.8 2.1 1.8
Osteoporosis (self-reported) 2.0 2.4 9.9 -2.1 -2.1 -1.2 -1.2 -1.1 -1.7 -1.9 -1.9 -0.7 -2.1 -1.4 -2.2 -2.2 -0.8 1.1 -1.3 -1.9 -3.1 -1.3 -1.1 -0.0 -0.9 0.1 -1.5 -0.5 -1.4 -2.1 -1.3 -1.0 -0.6
Osteoarthritis (self-reported) 2.2 2.8 8.4 -1.8 0.2 0.7 -0.3 0.8 0.0 -0.6 -1.6 -1.9 -0.5 -1.0 -0.7 -0.3 0.0 2.0 -2.5 0.4 -1.3 0.7 -2.8 -2.9 -2.8 -2.8 1.0 -2.2 -1.7 -1.5 -1.6 -2.6 -2.8
Medication: Aspirin 2.3 3.0 7.0 1.6 1.5 1.0 2.2 0.8 2.0 2.2 2.2 1.2 1.6 2.3 1.8 1.6 2.6 -2.4 2.0 1.6 2.0 -0.3 1.0 1.0 1.8 1.0 0.8 0.1 2.2 1.9 2.3 1.7 1.4
Medication: Gliclazide 0.4 0.4 2.0 0.5 1.4 0.5 -0.4 -0.8 0.7 0.6 0.4 1.4 0.8 0.6 0.8 0.9 0.8 -0.0 0.5 0.5 0.5 -0.2 0.5 -0.2 -0.0 -0.2 0.9 -0.1 0.1 1.1 0.1 0.2 0.1
Illnesses of father: None of the above (group 1) 0.3 0.4 2.6 0.5 0.4 0.9 -0.4 0.6 0.7 0.8 0.6 -1.0 0.8 0.4 0.7 0.8 0.2 0.2 0.2 1.0 1.1 1.6 -0.1 -0.3 -0.0 -0.2 0.6 0.0 0.4 0.7 0.2 0.2 -0.4
Smoking status: Current 0.9 1.4 5.3 -1.0 1.0 0.4 0.6 1.8 2.1 1.7 1.1 1.6 0.9 1.8 0.8 1.1 2.3 -0.4 0.3 1.8 0.6 1.3 -1.7 -0.6 -0.5 -0.5 0.8 0.3 0.9 0.7 1.0 0.0 -0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.4 2.9 8.6 -1.8 -2.3 -1.6 -1.6 -1.6 -2.1 -2.2 -1.8 -0.9 -2.4 -2.5 -2.2 -2.5 -2.9 0.7 -1.2 -2.4 -1.8 -1.8 0.3 0.8 0.1 0.8 -2.0 0.2 -1.2 -1.5 -1.1 -0.4 -0.0
Whole body water mass 0.3 1.6 5.9 -2.2 -0.5 0.6 -0.0 -2.4 1.0 0.4 0.3 1.5 -0.9 -0.7 -0.5 -0.8 -2.3 -1.4 0.9 -0.5 -1.7 -1.4 0.1 1.4 1.2 1.5 -1.4 1.4 2.0 -0.0 1.6 1.1 1.2
Leg predicted mass (right) 0.4 1.9 5.7 -2.1 -0.5 0.5 -0.2 -2.4 0.9 0.4 0.4 1.9 -0.9 -0.6 -0.4 -0.8 -2.4 -1.6 1.1 -0.5 -1.8 -1.3 0.4 1.8 1.4 1.8 -1.6 1.8 2.1 -0.0 1.7 1.3 1.5
Arm fat mass (left) 0.8 3.1 8.6 0.5 2.8 2.9 0.8 0.7 2.7 2.4 2.2 1.8 2.2 1.6 2.2 2.3 0.1 -1.6 1.8 2.5 1.5 1.8 0.9 -0.2 0.9 -0.3 1.8 -0.2 2.3 2.1 2.1 1.0 0.3
Number of self-reported non-cancer illnesses 0.5 0.8 3.1 -1.7 0.2 1.5 0.0 0.2 1.4 0.8 0.3 1.8 -0.2 1.3 0.0 0.1 1.4 -0.2 0.6 1.3 -0.2 0.0 0.6 0.4 0.9 0.4 -0.8 -1.2 1.6 0.2 0.9 1.1 0.1
Average weekly champagne plus white wine intake 0.4 0.6 3.2 1.7 0.4 -0.1 1.2 1.0 -0.7 -0.1 0.2 -1.8 0.4 0.1 0.6 0.2 0.3 0.2 0.4 -0.1 1.3 0.7 0.5 -0.6 -0.7 -0.8 0.9 -0.0 -0.4 -0.4 -0.5 -0.9 -0.4
Miserableness 0.5 0.9 3.8 -1.3 0.9 1.1 -0.1 -0.1 2.0 1.3 1.2 1.0 0.5 1.8 0.4 0.6 0.5 -1.1 0.6 1.4 -1.2 0.2 -1.4 0.4 0.2 0.3 0.0 0.6 1.3 -0.1 1.3 0.4 0.6
Guilty feelings 0.8 1.2 2.5 -0.7 1.3 1.6 0.4 1.4 0.9 0.5 0.0 -0.9 0.5 1.5 0.4 0.6 0.9 1.1 -0.7 1.3 -1.4 1.2 -1.3 -1.4 -1.5 -1.4 0.7 -1.1 -0.7 -1.2 -0.7 -1.5 -1.3
Wears glasses or contact lenses 0.8 0.9 2.4 -0.9 -1.3 -1.0 -0.5 -0.7 -0.5 -0.4 0.1 1.3 -1.0 -0.6 -0.8 -1.1 -0.5 -0.8 0.2 -0.9 -1.1 -1.0 0.9 1.5 1.3 1.6 -1.4 1.1 0.3 0.1 0.6 0.9 1.1
Ever taken oral contraceptive pill 3.2 3.6 7.6 1.9 1.9 1.9 2.3 0.3 1.8 2.0 2.4 1.3 2.2 1.8 2.7 2.2 0.6 -2.5 2.5 1.7 1.9 -0.2 1.8 0.7 1.4 0.7 1.9 2.0 2.0 2.8 2.4 1.5 1.6
Hearing aid user 0.4 0.5 1.8 -0.2 0.2 -0.2 -0.9 -0.5 -0.8 -0.9 -0.7 -1.3 -0.3 -0.4 -0.5 -0.4 0.1 0.7 -0.7 -0.8 0.1 0.2 -0.6 -0.8 -0.9 -0.8 0.1 -1.3 -0.9 -0.5 -0.8 -0.9 -1.0
Mother’s age at death 0.4 0.5 1.9 0.7 -1.2 -1.0 -0.1 -0.1 -1.3 -1.1 -0.7 -1.3 -0.7 -0.4 -1.0 -0.8 1.4 0.4 -0.4 -1.1 0.1 -0.5 0.7 -0.1 0.1 -0.1 -0.2 -0.4 -1.0 0.5 -0.4 -0.1 -0.0
Financial situation satisfaction 1.6 2.0 5.2 1.0 2.1 2.3 2.2 1.0 1.6 1.9 1.6 0.2 2.2 1.2 1.9 2.2 0.1 -0.6 1.2 2.0 1.6 1.7 1.1 -0.6 0.0 -0.7 1.7 0.2 0.9 1.2 0.9 0.0 0.0
Tinnitus: Yes, now most or all of the time 1.4 1.6 4.4 -1.1 -1.4 -2.1 -0.8 -1.0 -1.5 -1.8 -1.5 0.2 -1.4 -1.9 -1.2 -1.4 -1.1 0.5 -1.1 -2.1 -1.5 -1.9 -1.3 -0.3 -1.1 -0.3 -0.6 -0.1 -1.4 -1.4 -1.1 -1.1 -0.4
Commuting to job workplace: Public transport 1.6 1.9 4.8 1.1 -0.1 -0.1 1.4 -1.3 0.4 0.7 1.2 1.5 -0.0 1.0 0.3 -0.1 -0.6 -2.0 1.9 -0.4 0.8 -2.1 1.8 2.1 2.0 2.0 -0.8 1.6 1.5 1.0 1.7 1.8 2.2
Eye problems/disorders: Glaucoma 0.8 0.9 2.8 -1.5 -1.1 -0.7 -1.6 -0.2 -1.1 -1.3 -1.0 1.4 -1.0 -1.0 -1.0 -1.0 -1.7 0.5 -0.7 -1.2 -1.6 -0.6 0.5 -0.3 -0.1 -0.3 -0.7 -0.5 -0.1 -0.8 -0.4 -0.5 -0.6
Medication: Blood pressure 0.2 0.4 1.7 -0.3 0.9 0.7 -0.2 0.3 1.2 0.8 0.4 1.2 0.3 1.1 -0.1 0.4 1.1 0.2 -0.1 1.3 -0.0 0.8 -0.8 -0.1 0.0 -0.1 -0.3 -0.5 0.7 -0.0 0.3 0.3 -0.1
Pain type(s) experienced in last month: Hip pain 4.0 5.0 12.3 -3.1 0.0 0.2 -1.0 0.7 -0.6 -1.2 -2.4 -2.3 -1.2 -0.7 -1.7 -1.0 0.3 3.4 -3.2 0.2 -1.6 1.7 -3.4 -3.0 -3.2 -2.9 -0.2 -3.4 -2.3 -2.9 -2.9 -2.8 -3.5
Supplements: Fish oil (including cod liver oil) 0.1 0.2 1.3 -0.5 -0.0 -0.1 -0.3 -0.9 0.1 -0.1 -0.2 -0.3 -0.3 -0.3 -0.1 -0.2 0.9 0.1 0.1 0.3 -0.5 -0.7 -0.2 0.3 0.0 0.2 0.1 1.2 0.2 0.1 0.1 0.3 0.5
High cholesterol (Self-reported) 0.5 0.8 3.0 -0.9 0.9 1.5 1.7 0.5 1.6 1.2 0.3 -0.0 0.6 1.5 0.3 0.7 0.4 0.1 -0.1 1.3 0.2 1.1 -1.2 -0.9 -0.7 -1.0 0.7 -1.2 0.5 0.1 0.4 -0.4 -0.9
Medication: Bendroflumethiazide 0.8 1.2 3.9 0.9 1.1 1.4 0.7 -0.2 1.7 1.4 1.4 1.1 0.8 2.0 0.6 0.8 0.1 -1.1 1.3 1.1 0.5 -0.5 1.1 0.8 1.3 0.8 0.3 0.4 1.4 1.5 1.5 1.4 1.0
Medication: Paracetamol 1.2 1.9 5.5 0.7 2.0 1.9 0.6 2.4 1.4 1.2 0.6 -1.6 1.8 1.2 1.3 1.8 0.3 0.4 -0.2 2.1 1.0 1.8 0.1 -1.9 -0.9 -1.8 1.9 -1.7 -0.1 0.8 0.1 -0.8 -1.3
Medication: Lisinopril 0.8 1.0 2.9 -1.1 -1.7 -1.3 -1.5 -0.9 -0.8 -0.9 -0.7 1.3 -1.2 -0.6 -1.4 -1.4 -0.1 -0.2 -0.1 -0.8 -1.3 -1.3 0.3 0.9 0.9 0.9 -1.6 -0.3 0.3 -0.2 0.0 1.0 0.7
Medication: Atorvastatin 1.2 1.4 7.4 -2.7 -1.4 -0.8 -0.8 -1.3 -0.7 -0.9 -1.2 -1.1 -1.6 -1.2 -1.7 -1.6 -2.0 0.6 -1.4 -1.5 -1.4 -0.3 -1.4 0.0 -0.4 0.0 -1.3 -0.8 -0.8 -1.0 -0.7 -0.5 -0.6
Illnesses of father: High blood pressure 1.0 1.2 4.2 -0.7 1.1 0.5 1.3 -0.7 1.4 1.2 1.0 0.7 0.0 1.4 0.2 0.2 0.6 -1.2 1.5 0.8 -0.7 -0.7 1.0 1.4 1.6 1.2 -0.7 0.2 2.0 0.6 1.5 1.7 1.2
Alcohol drinker status: Never 0.7 0.9 4.3 0.7 0.9 2.1 0.8 0.8 1.2 1.4 1.2 1.2 1.4 0.7 1.4 1.4 -0.5 -0.9 0.7 0.9 0.8 0.5 0.3 -0.2 0.3 -0.2 1.0 -0.1 0.6 1.0 1.0 0.2 0.2
Ever smoked 1.9 3.3 6.9 2.5 2.0 1.7 1.3 2.4 2.0 2.1 2.3 0.5 2.5 2.3 2.3 2.4 2.0 -1.2 1.9 2.2 2.6 1.3 1.4 -0.2 0.7 -0.2 2.2 0.4 1.1 2.5 1.5 0.9 0.6
Basal metabolic rate 0.3 1.5 4.9 -1.8 0.1 1.1 0.1 -2.0 1.4 0.9 0.7 1.8 -0.3 -0.3 0.0 -0.2 -1.9 -1.6 1.2 0.0 -1.2 -0.9 0.4 1.3 1.3 1.3 -0.9 1.2 2.2 0.5 1.9 1.2 1.2
Leg fat percentage (left) 0.9 3.3 9.7 0.8 3.1 2.8 0.8 1.8 2.0 2.0 1.4 0.7 2.5 1.5 2.2 2.6 0.9 0.0 0.3 2.8 2.3 3.1 0.4 -1.8 -0.5 -2.0 2.7 -2.0 0.6 1.5 0.5 -0.5 -1.5
Arm fat-free mass (left) 0.2 1.0 5.2 -2.3 -0.4 0.7 -0.1 -2.2 0.9 0.3 -0.0 1.0 -0.9 -0.7 -0.7 -0.8 -2.0 -0.9 0.4 -0.4 -1.7 -0.9 -0.4 0.9 0.7 0.9 -1.1 0.5 1.4 -0.2 1.1 0.6 0.5
Number of operations (self-reported) 0.5 0.7 3.5 0.2 -0.3 0.5 -0.1 1.1 -0.4 -0.5 -0.6 -1.9 -0.0 0.3 -0.0 -0.0 1.0 0.7 -0.8 -0.0 -0.3 0.3 0.3 -1.5 -0.9 -1.5 1.0 -0.9 -1.1 0.1 -0.6 -1.3 -1.2
Average weekly beer plus cider intake 1.6 2.4 6.8 1.4 2.5 1.3 2.2 1.5 1.7 1.8 1.1 -1.0 1.9 0.9 1.9 2.0 -0.7 0.2 -0.1 2.3 1.9 2.6 -1.7 -1.7 -1.4 -1.6 2.2 -0.5 -0.1 0.4 0.0 -0.9 -1.1
Irritability 0.3 0.5 1.6 0.8 0.5 0.5 1.3 1.0 0.0 0.3 0.4 0.1 0.8 1.1 0.7 0.6 1.0 0.1 0.2 0.6 0.9 0.9 -0.1 -0.8 -0.7 -0.9 1.2 -0.8 -0.8 0.1 -0.4 -0.7 -0.6
Risk taking 0.4 0.6 1.3 -0.9 0.5 0.9 -0.4 -0.8 1.1 0.9 0.7 1.1 0.5 0.6 0.7 0.6 0.8 -0.8 0.7 0.4 -1.0 -0.9 0.3 0.5 0.7 0.2 0.6 0.4 0.8 1.2 1.0 0.7 0.5
Ever had prostate specific antigen (PSA) test 0.9 1.0 3.2 -0.3 -1.7 -1.8 -0.5 -1.0 -1.5 -1.3 -1.2 -0.0 -1.2 -0.9 -1.3 -1.2 -0.3 1.3 -1.1 -1.0 -0.6 0.2 -0.9 -0.1 -0.6 0.1 -0.8 -0.6 -1.5 -0.8 -1.6 -0.3 -0.6
Fractured/broken bones in last 5 years 1.0 1.3 3.8 -0.4 0.4 0.8 -0.3 1.5 -0.4 -0.4 -0.6 -1.9 0.7 -0.4 0.3 0.6 0.9 1.1 -1.1 0.1 -0.2 1.2 -0.9 -1.7 -1.8 -1.6 1.1 -1.2 -1.5 -1.4 -1.3 -1.9 -1.7
Age started oral contraceptive pill 1.4 1.8 4.3 -1.8 -1.2 -1.0 -1.4 -0.7 -1.2 -1.5 -1.9 -1.2 -1.6 -1.6 -1.8 -1.5 -1.2 1.8 -2.1 -0.5 -1.6 -0.4 -0.6 -0.9 -0.7 -1.0 -1.4 -1.5 -1.1 -1.0 -1.3 -1.0 -1.4
Diastolic blood pressure, automated reading 0.5 1.5 4.8 0.3 0.5 0.4 0.5 0.8 1.9 1.7 1.4 2.2 1.0 1.4 1.2 1.1 0.8 -0.7 1.1 1.9 0.5 0.9 0.5 0.8 1.0 0.7 0.2 1.7 1.6 1.8 1.2 1.7 1.3
Ever depressed for a whole week 1.0 1.3 5.0 -2.2 -0.5 0.4 -0.9 0.9 0.4 -0.1 -0.8 -1.1 -0.7 -0.7 -0.9 -0.5 -1.6 1.2 -1.7 0.6 -1.5 1.1 -2.0 -1.4 -1.2 -1.3 -0.4 -1.3 -0.3 -1.3 -0.4 -1.3 -1.5
Unable to work because of sickness or disability 0.1 0.2 0.8 -0.5 0.1 0.9 0.8 0.6 0.5 0.6 0.4 0.6 0.4 0.4 0.4 0.4 0.1 -0.0 0.5 0.6 -0.4 0.7 0.4 0.1 0.2 0.3 0.1 -0.0 0.2 -0.2 0.1 0.4 0.2
Commuting to job workplace: Cycle 0.3 0.3 2.1 -1.4 -0.3 0.1 -0.4 -1.0 0.5 0.2 0.3 0.8 -0.2 0.3 -0.6 -0.2 -0.1 -0.3 0.2 -0.0 -1.1 -0.3 -0.3 0.5 0.4 0.6 -0.9 0.4 0.8 -0.5 0.6 0.3 0.3
Myopia 0.2 0.3 1.4 0.0 -0.7 -0.8 0.8 -0.5 -0.0 0.1 0.1 1.2 -0.6 0.2 -0.4 -0.5 0.4 -0.3 0.1 -0.3 -0.3 -0.4 0.1 0.7 0.6 0.8 -0.4 0.7 0.0 0.8 0.3 0.7 0.7
Vascular/heart problems diagnosed by doctor 0.3 0.8 2.5 0.3 -0.8 -1.0 0.1 -0.8 -1.4 -1.2 -0.7 -1.5 -0.8 -1.3 -0.3 -0.9 -1.2 0.1 -0.3 -1.6 -1.1 -1.0 -0.4 0.2 -0.6 0.2 -0.0 1.4 -1.1 -0.9 -0.7 -0.8 0.1
Cholesterol lowering medication 0.6 1.0 3.7 0.0 0.4 0.7 0.8 0.5 -0.3 -0.3 -0.6 -0.3 0.4 0.2 0.1 0.4 0.3 0.8 -0.9 -0.1 1.3 0.8 -1.3 -1.7 -1.6 -1.6 1.1 -1.9 -1.2 -0.4 -0.9 -1.4 -1.7
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 1.8 0.6 0.2 0.2 0.3 0.7 -0.5 -0.5 -0.9 -0.8 -0.4 -0.7 -0.0 -0.3 -0.2 1.0 -1.2 0.2 0.4 0.1 -0.3 -1.3 -1.0 -1.3 0.7 -1.0 -1.3 0.2 -0.8 -1.2 -1.1
Pain experienced in last month 1.0 1.7 10.3 3.2 -0.1 0.1 1.0 -0.2 -0.0 0.7 1.3 -0.6 1.3 0.5 1.0 0.9 0.0 -1.7 1.9 -0.5 2.3 -0.6 1.0 1.5 0.9 1.3 0.8 2.4 0.6 1.2 0.9 1.1 1.8
Supplements: Calcium 1.1 1.2 3.1 -0.5 0.0 -0.5 -1.5 0.1 -0.6 -1.0 -1.2 -1.0 -0.2 -0.9 -0.4 -0.2 0.6 1.8 -1.5 0.1 -0.0 0.5 -1.0 -1.5 -1.6 -1.6 0.3 -1.1 -1.3 -1.4 -1.6 -1.7 -1.6
Basal cell carcinoma (self-reported) 0.4 0.4 2.7 -0.2 0.4 -0.6 0.2 -1.3 0.1 0.2 0.2 0.4 -0.3 0.4 0.2 -0.2 1.6 -0.7 0.5 0.0 0.1 -1.1 1.1 0.7 1.1 0.5 -0.4 0.1 1.0 0.5 0.8 0.7 0.6
Heart attack/myocardial infarction (self-reported) 0.1 0.2 0.8 -0.2 -0.5 -0.9 0.3 0.2 -0.1 -0.1 -0.1 -0.7 -0.8 0.1 -0.6 -0.8 0.6 -0.3 -0.3 -0.5 -0.7 -0.2 0.1 0.3 0.5 0.2 -0.5 -0.0 -0.1 0.3 0.3 0.2 0.2
Deep venous thrombosis (DVT) (self-reported) 0.8 1.0 3.9 1.6 0.6 1.0 0.4 1.5 0.1 0.2 0.2 -0.7 1.0 0.8 0.7 0.9 1.1 0.6 -0.2 0.8 1.2 1.3 -0.5 -1.4 -1.4 -1.4 2.0 0.1 -1.5 0.6 -0.7 -1.2 -0.8
Heart disease (siblings) 0.6 0.8 5.5 -1.5 -0.2 0.4 -0.2 0.2 -0.0 0.0 -0.6 0.1 0.0 -0.2 -0.3 0.1 -0.2 1.2 -1.1 0.8 0.1 1.1 -0.8 -1.2 -0.9 -1.1 0.2 -2.4 -0.8 -1.0 -1.1 -1.0 -1.6
Alcohol drinker status: Previous 0.5 0.6 2.6 1.0 0.4 -0.5 0.5 1.5 0.1 0.3 0.7 0.9 0.6 0.4 0.7 0.5 0.1 -0.7 0.9 0.4 1.3 -0.1 1.6 0.5 0.9 0.5 0.4 0.1 0.5 1.1 0.5 0.8 0.6
Pack years of smoking 0.5 0.8 2.1 0.5 0.9 0.5 1.4 0.5 1.3 1.4 1.4 0.8 0.6 1.4 1.0 0.7 0.7 -1.2 1.1 0.6 0.5 0.2 0.2 0.5 0.6 0.4 0.6 0.9 1.0 0.8 1.3 0.6 0.8
Impedance of whole body 0.5 2.4 12.2 3.5 1.4 0.1 0.8 3.4 -0.1 0.8 1.1 1.2 2.1 1.6 1.8 1.9 1.9 -0.3 0.5 1.1 2.6 0.9 1.9 -0.9 0.3 -1.1 2.2 -0.6 -0.4 2.0 0.3 0.1 -0.1
Leg fat mass (left) 0.4 1.5 5.5 -0.4 2.1 2.3 0.3 0.4 1.9 1.6 1.1 1.5 1.4 0.9 1.3 1.5 -0.1 -0.6 0.6 1.9 0.9 1.8 0.6 -0.7 0.3 -0.9 1.2 -1.1 1.4 1.2 1.1 0.2 -0.6
Arm predicted mass (left) 0.2 1.2 6.9 -2.6 -0.4 0.8 -0.3 -2.2 0.8 0.2 -0.2 0.9 -1.1 -0.9 -0.9 -0.9 -2.3 -0.7 0.1 -0.5 -2.0 -0.7 -0.5 0.7 0.5 0.7 -1.3 0.3 1.4 -0.5 1.0 0.4 0.3