Hub : Genes

WDR48

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0870 0.0310 1.8e-04 0.006 0.013 0.000 0.012 0.003 6.0e-02 8.6e-03 2.8e-01 1.1e-02 1.3e-01
2 GTEx Artery Tibial 0.0648 0.0267 2.7e-03 0.035 NA 0.045 NA 0.040 8.3e-04 NA 1.9e-04 NA 4.1e-04
3 GTEx Nerve Tibial 0.0699 0.0282 2.3e-03 0.067 NA 0.046 NA 0.046 1.8e-05 NA 3.5e-04 NA 3.2e-04
4 GTEx Skin Sun Exposed Lower leg 0.0850 0.0370 5.6e-03 0.044 NA 0.025 NA 0.031 1.5e-04 NA 3.2e-03 NA 1.4e-03
5 ROSMAP Brain Pre-frontal Cortex 0.1124 0.0317 2.4e-10 0.114 0.093 0.114 0.106 0.116 1.8e-14 5.7e-12 2.0e-14 1.8e-13 1.2e-14
6 YFS Blood 0.4510 0.0343 0.0e+00 0.613 0.591 0.611 0.611 0.612 2.8e-262 1.9e-247 7.8e-261 1.1e-260 1.4e-261
7 TCGA Kidney Renal Papillary Cell Carcinoma 0.0690 0.0530 2.7e-03 0.032 0.027 0.047 NA 0.034 5.9e-03 1.0e-02 1.1e-03 NA 4.8e-03
8 TCGA Thyroid Carcinoma 0.0690 0.0430 5.3e-03 -0.002 0.015 0.006 NA 0.002 5.5e-01 1.3e-02 7.8e-02 NA 2.1e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.8 1.3 4.9 -2.2 -1.6 -0.3 -0.8 1.0 -1.2 -0.1 0.2
Bipolar Disorder or Schizophrenia 0.4 1.0 2.3 -1.3 -1.3 -0.6 -0.7 0.5 -0.8 -0.5 -1.5
Depressed Affect (Nagel 2018) 0.5 1.1 4.6 1.2 1.2 0.0 0.5 -0.0 -0.3 -0.9 -2.2
Depression (Nagel 2018) 0.5 0.8 2.5 1.0 -0.1 1.2 -0.6 -0.5 0.5 -0.7 -1.6
Intelligence (Savage-Jansen 2018) 0.3 1.0 2.6 0.8 -0.1 0.8 0.0 -1.6 1.4 -1.5 0.2
Neuroticism (Nagel 2018) 0.4 1.1 3.0 -0.4 0.2 -1.3 -0.3 1.6 -1.7 0.6 -0.9
Schizophrenia (2018) 0.3 0.7 4.5 0.1 -0.4 -0.5 -0.3 -0.2 0.0 -0.6 -2.1
Schizophrenia vs Biploar Disorder 0.5 0.7 3.7 -0.4 0.1 -0.6 0.1 0.2 0.1 1.2 1.9
Worry (Nagel 2018) 0.5 1.1 2.6 -0.6 -0.9 -1.3 -0.9 1.5 -1.6 0.5 0.4
Alzheimer’s Disease (in mother) 0.9 1.1 2.1 -0.9 -0.4 -1.5 -0.6 1.2 -1.1 1.2 1.0
Alzheimer’s Disease (in father) 1.3 1.4 4.9 -2.2 -0.1 -0.4 0.2 1.6 -1.6 0.3 1.0
Alzheimer’s Disease (including proxy) 1.1 1.5 3.7 -1.6 -0.6 -1.2 -0.6 1.9 -1.6 1.1 0.4
Crohns Disease (2017) 1.2 2.6 6.0 -2.4 0.6 -0.9 0.4 2.0 -1.8 2.2 1.2
Irritable Bowel Disease (IBD) 1.1 2.5 4.9 -1.9 -0.8 -1.3 -1.1 2.2 -1.8 2.2 -0.4
Ulcerative Colitis (UC) 1.2 2.2 3.9 -1.2 -1.6 -1.1 -2.0 1.7 -1.1 1.3 -1.8
Major Depression (MDD) 0.6 0.7 2.2 1.2 0.3 -0.4 -1.2 0.3 -0.2 -0.5 -1.5
Reaction Time 0.9 1.7 7.6 2.8 0.3 1.1 -0.8 -1.0 1.4 -0.7 -0.8
Verbal and Numeric Reasoning (VNR) 1.7 4.1 8.6 2.6 0.8 2.0 0.3 -2.6 2.2 -2.9 -0.9
Breast Cancer 0.4 0.8 2.7 1.6 -0.5 0.9 -0.2 -0.8 0.7 -1.2 -0.5
Ovarian Cancer 0.5 0.6 1.9 0.9 -0.2 0.4 -1.1 -0.2 0.1 -1.4 -0.9
Prostate Cancer 0.1 0.2 0.9 1.0 0.2 0.3 -0.3 -0.3 0.2 0.1 -0.4
Age at First Birth 0.2 0.3 0.8 -0.1 0.7 0.6 0.7 0.4 -0.3 -0.3 -0.9
Bipolar Disorder (2011) 0.8 0.8 2.6 -1.6 -0.1 -0.8 0.4 1.0 -1.1 0.5 0.6
Body Mass Index (BMI) (2010) 0.5 0.7 2.1 -1.4 -1.5 -0.1 -0.9 0.7 -0.5 0.5 -0.2
Coronary Artery Disease (CAD) 3.3 3.9 5.8 2.1 2.3 2.2 1.8 -2.3 2.4 -1.6 -0.2
Crohns Disease (2012) 0.8 1.2 3.7 -1.9 -0.2 -0.9 -0.3 1.3 -1.4 1.0 0.7
Mean Putamen Volume 1.1 1.2 2.5 -0.1 -1.2 -1.4 -0.8 1.6 -1.4 1.1 -0.2
Fasting Glucose 0.4 0.5 3.0 -0.4 -0.6 0.1 -0.1 -0.6 0.3 -0.3 1.7
HbA1C 0.7 0.8 2.1 0.6 1.5 1.1 0.8 -0.8 1.0 -0.5 0.0
HDL Cholesterol 2.2 3.6 8.3 -2.2 -1.3 -1.7 -1.1 1.8 -2.1 1.4 2.9
LDL Cholesterol 0.1 0.1 0.5 -0.0 -0.7 0.4 -0.2 0.3 -0.1 0.0 -0.2
Lupus 1.6 2.4 6.4 0.8 -0.7 1.2 -0.3 -2.0 1.8 -2.5 -1.9
Neuroticism (2016) 0.6 0.9 4.2 1.3 0.6 0.8 -0.0 -0.2 0.5 -0.2 -2.0
Primary Biliary Cirrhosis 0.5 0.7 1.4 -0.9 0.8 0.8 1.2 -0.8 0.9 -0.4 0.5
Rheumatoid Arthritis 1.2 1.6 3.1 1.4 0.9 1.3 0.2 -1.3 1.5 -1.2 -1.8
Schizophrenia (2014) 0.5 1.2 2.8 -1.4 -1.7 -1.0 -0.8 0.8 -1.0 0.3 -1.1
Triglycerides 0.8 1.4 2.4 0.3 0.6 1.1 1.2 -1.6 1.4 -1.5 -1.0
Type 2 Diabetes (T2D) (2012) 0.1 0.1 0.5 -0.2 0.6 0.1 0.0 -0.1 0.0 0.7 -0.3
Ulcerative Colitis 0.5 0.8 2.9 -0.2 -1.2 -0.3 -1.7 0.7 -0.4 0.6 -0.7
Blood Eosinophil Count 1.3 10.0 15.6 2.9 3.9 4.0 2.2 -3.6 3.5 -3.2 -0.7
Blood Platelet Count 1.0 11.9 34.6 -2.4 4.6 1.0 5.0 -2.1 0.2 -2.0 5.9
Blood Red Count 0.4 3.6 10.7 -0.7 2.2 1.3 3.3 -2.1 1.6 -1.4 1.6
Blood White Count 1.5 11.1 17.4 0.3 4.2 3.9 3.8 -3.9 2.8 -4.0 1.4
Heel T-Score 0.1 0.5 2.0 0.2 -0.8 0.3 -0.3 -0.9 0.3 -1.4 -0.7
BMI 0.8 4.4 13.4 2.7 -0.2 1.7 1.3 -1.7 1.7 -2.2 -3.7
Height 0.2 4.1 12.8 1.9 -0.3 2.1 -0.3 -2.6 2.2 -3.6 -0.5
Waist Hip Ratio (WHR) 0.3 1.1 6.9 -0.9 0.5 0.3 0.9 0.1 -0.5 -0.2 2.6
Systolic Blood Pressure 0.4 2.1 5.4 1.3 0.9 1.5 1.2 -2.2 2.3 -0.5 -0.4
Smoking Status 0.3 0.7 1.3 0.8 1.1 0.5 1.0 -0.6 0.6 -0.4 -1.1
Allergy or Eczema 1.0 2.7 4.6 1.7 -0.2 2.1 -0.1 -2.1 2.1 -2.1 -1.1
Cardiovascular Disease 0.9 3.1 5.8 1.9 0.9 1.3 0.3 -2.1 1.8 -2.2 -2.4
Hypothyroidism (self reported) 0.9 2.0 4.5 0.5 0.9 1.9 0.7 -2.1 2.1 -1.4 0.0
Respiratory disease 0.6 1.3 5.2 0.3 -0.5 0.3 -0.7 -1.5 1.1 -2.3 -1.1
Type 2 Diabetes (T2D) (2018) 1.6 3.0 6.6 1.9 1.3 2.0 1.2 -1.9 1.7 -2.6 -0.6
Lung FEV1/FVC ratio 0.2 1.1 2.6 0.8 -1.6 -0.7 -1.5 1.0 -1.0 0.6 -0.2
Lung FVC 1.8 9.2 18.3 -0.8 -3.7 -3.1 -4.3 3.4 -2.8 3.3 -1.0
Neuroticism 0.3 0.6 1.9 -0.5 0.1 -0.9 -0.2 1.3 -1.4 0.2 -0.5
Chronotype (morning person) 1.2 2.7 6.7 1.7 2.6 1.5 1.6 -1.6 1.8 -1.1 -0.5
Hair Pigment 0.1 2.1 3.6 1.1 1.3 1.5 0.9 -1.9 1.7 -1.5 -1.3
Tanning 0.0 0.1 0.3 0.1 0.4 -0.2 0.2 -0.5 0.3 -0.1 -0.6
Hand grip strength (left) 1.2 3.2 10.3 0.8 -2.5 -0.3 -3.2 0.3 0.3 -0.3 -2.9
Number of treatments/medications taken 0.3 0.5 1.5 0.6 -0.3 0.1 -0.8 -0.5 0.1 -1.2 -0.9
Average weekly spirits intake 0.5 0.6 1.6 -0.9 -0.3 -1.3 0.7 0.2 -0.5 0.1 1.1
Sensitivity / hurt feelings 0.2 0.3 0.7 -0.5 0.5 -0.0 0.8 0.4 -0.2 0.8 0.2
Frequency of depressed mood in last 2 weeks 2.1 3.0 5.8 2.3 0.5 2.4 -0.0 -1.8 1.9 -1.7 -1.6
Hearing difficulty/problems: Yes 2.9 4.4 7.4 -0.7 -2.1 -2.3 -2.7 2.6 -2.5 2.0 0.5
Relative age of first facial hair 0.5 0.9 4.0 -2.0 -0.1 -1.1 0.1 0.8 -1.1 0.7 0.2
Other serious medical condition/disability diagnosed by doctor 1.2 1.5 4.7 2.2 -1.1 0.1 -1.5 -0.6 1.0 -0.6 -1.5
Ever used hormone-replacement therapy (HRT) 1.0 1.2 4.9 -0.6 -0.6 -2.2 -0.4 1.1 -1.6 0.5 0.1
Ever had hysterectomy (womb removed) 0.6 0.7 1.3 0.5 -1.0 -0.8 0.0 0.7 -0.6 1.2 1.1
Systolic blood pressure, automated reading 0.1 0.3 0.7 0.3 0.2 -0.6 0.6 -0.9 0.6 0.3 0.4
Eye problems/disorders: Diabetes related eye disease 2.4 2.7 5.6 0.3 2.4 1.7 2.3 -1.3 1.0 -1.9 1.0
Angina 3.2 4.2 6.8 -1.4 -2.0 -2.0 -1.5 2.6 -2.6 2.3 1.6
Medication for hormone replacement therapy 1.8 2.0 4.2 -0.4 -0.8 -2.1 -1.5 1.8 -1.7 1.5 -0.4
Vitamin and mineral supplements 1.2 1.6 4.3 -0.1 2.1 1.2 1.7 -1.2 1.1 -0.9 -1.0
Supplements: Zinc 2.2 2.4 3.8 -0.6 -1.7 -1.9 -1.3 1.7 -1.9 1.3 1.5
Medication: Co-codamol 0.3 0.4 1.4 -0.3 1.2 -0.3 0.8 0.2 -0.3 0.4 -0.7
Medication: Metformin 2.4 3.4 7.4 1.6 1.2 2.1 1.4 -2.3 2.0 -2.7 0.6
Diabetes (father) 1.3 1.7 3.2 1.8 0.0 1.4 -0.4 -1.2 1.7 -0.8 -1.8
Diabetes (mother) 0.6 0.8 1.3 0.4 0.7 0.8 1.1 -1.1 0.9 -0.7 1.0
Severe depression (siblings) 0.4 0.5 1.5 0.4 0.9 -0.4 0.1 0.9 -1.2 -0.1 -0.2
Pack years adult smoking proportion 0.9 1.3 3.8 2.0 0.7 1.8 0.6 -0.6 0.8 -1.0 -0.9
Impedance of leg (right) 0.8 3.9 17.1 -1.6 2.5 0.3 2.1 -0.9 0.6 0.3 4.1
Leg fat-free mass (left) 0.6 3.2 11.9 1.8 -1.2 0.8 -0.8 -1.0 0.8 -2.5 -3.5
Trunk fat percentage 0.8 3.3 7.7 1.6 1.4 1.5 2.8 -2.2 1.7 -1.9 0.6
Hand grip strength (right) 0.5 1.3 4.6 -0.3 -1.5 -0.1 -2.1 0.1 0.2 -0.5 -1.8
Townsend deprivation index at recruitment 3.4 4.8 8.0 1.9 2.1 2.5 2.1 -2.6 2.8 -1.8 -1.3
Current tobacco smoking 1.2 1.9 4.8 2.2 1.0 0.7 1.1 -1.0 0.8 -1.5 -2.0
Average weekly fortified wine intake 0.1 0.2 0.5 -0.2 -0.7 0.4 -0.3 0.0 0.1 -0.2 0.7
Maternal smoking around birth 2.5 3.5 5.8 2.4 2.2 2.0 2.2 -1.7 1.7 -1.2 -1.4
Fed-up feelings 1.4 2.5 4.5 2.1 1.3 2.0 1.0 -1.0 1.1 -1.6 -2.0
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 2.2 1.3 -0.3 1.5 -0.1 -1.1 1.1 -1.4 -1.4
Relative age voice broke 0.1 0.1 0.3 0.4 0.4 -0.6 0.3 0.1 -0.3 0.2 0.6
Taking other prescription medications 0.4 0.7 1.9 0.5 -0.7 0.1 -0.6 -0.9 0.7 -1.4 -1.1
Age when periods started (menarche) 0.3 0.8 1.6 1.1 0.9 1.1 -0.4 -1.0 0.8 -1.2 -0.3
Bilateral oophorectomy (both ovaries removed) 0.2 0.3 0.7 0.1 0.6 0.5 0.5 -0.8 0.6 -0.3 0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.3 0.9 -0.6 -0.3 0.1 0.7 -0.9 0.5 -0.6 0.4
Tinnitus: Yes, but not now, but have in the past 0.6 0.6 3.9 -0.1 -0.0 0.8 0.5 0.1 -0.1 -0.3 -2.0
Qualifications: CSEs or equivalent 0.5 0.7 2.6 -1.6 0.3 0.7 1.2 -0.2 0.0 -0.7 -0.8
Serious illness, injury or assault to yourself 0.6 0.8 2.7 -0.7 -1.2 -0.4 -1.7 0.5 -0.4 0.3 0.7
High blood pressure 0.5 1.5 3.2 1.6 1.0 0.4 1.1 -1.8 1.1 -1.6 -0.5
Hayfever, allergic rhinitis or eczema 1.9 4.2 7.5 1.7 -0.0 2.5 -0.4 -2.6 2.7 -2.4 -2.0
Multivitamins +/- minerals 0.6 0.8 2.7 -0.2 -1.5 -0.7 -1.7 0.3 -0.4 -0.0 -0.4
Stomach or abdominal pain in last month 0.5 0.7 3.1 -1.1 0.1 -0.0 0.5 -0.2 0.1 0.9 1.8
Supplements: Glucosamine 6.2 8.1 16.4 -1.1 -4.1 -3.2 -3.5 2.9 -2.6 2.9 0.8
Diverticular disease/diverticulitis (self-reported) 0.3 0.3 1.1 0.3 0.9 -0.0 1.1 -0.0 0.3 0.8 0.1
Medication: Atenolol 2.3 2.9 5.9 1.6 1.6 1.8 1.2 -1.8 1.6 -1.5 -2.4
Medication: Levothyroxine sodium 0.5 0.8 1.7 -0.7 0.7 1.2 0.5 -1.2 1.3 -0.8 -0.2
Sitting height 0.1 0.9 3.8 -0.9 -0.2 1.0 -1.2 -0.5 0.1 -2.0 0.2
Chronic bronchitis/emphysema (father) 3.9 4.6 9.2 -2.7 -0.9 -2.7 -1.1 2.8 -3.0 1.7 0.5
High blood pressure (mother) 0.4 0.5 1.8 0.6 -1.4 0.4 -1.1 0.0 -0.1 -0.6 -0.5
Body mass index (BMI) 0.5 2.2 4.4 1.8 0.3 1.1 1.7 -1.3 1.0 -1.9 -2.1
Impedance of leg (left) 0.6 3.1 15.2 -1.6 1.9 -0.1 1.6 -0.2 -0.0 0.9 3.9
Leg predicted mass (left) 0.6 3.1 11.5 1.8 -1.2 0.8 -0.7 -1.0 0.8 -2.5 -3.4
Trunk fat mass 0.7 3.2 5.9 1.8 0.9 1.6 2.2 -2.2 1.7 -2.4 -0.5
Waist circumference 0.2 0.9 2.8 1.1 -0.2 0.7 1.2 -0.9 0.3 -1.7 -0.4
Number of incorrect matches in round 0.6 1.0 2.6 0.2 -1.0 -1.2 -1.4 0.4 -0.5 0.3 -1.6
Past tobacco smoking 1.1 2.0 4.7 -0.4 -1.6 -1.4 -2.2 1.6 -1.6 0.7 -0.8
Alcohol usually taken with meals 1.5 2.5 7.2 -0.9 -2.2 -0.7 -2.7 0.8 -0.3 1.8 1.6
Nervous feelings 0.1 0.2 1.0 -1.0 -0.2 0.0 -0.2 0.4 -0.5 -0.3 0.1
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 2.4 1.6 0.1 0.7 0.3 -0.1 0.4 -0.4 -0.8
Hearing difficulty/problems with background noise 0.7 1.1 3.2 -0.6 -0.5 -1.1 -0.7 1.0 -1.2 0.9 1.8
Hair/balding pattern: Pattern 2 2.1 2.7 5.2 -1.7 0.0 -2.0 0.2 1.9 -2.3 1.8 1.5
Had menopause 1.4 1.7 3.8 -1.3 -1.9 -1.9 -1.3 1.0 -1.4 0.4 0.1
Had other major operations 0.5 0.6 2.9 0.1 0.3 -0.1 0.0 0.9 -0.9 0.4 1.7
Forced vital capacity (FVC) 0.2 0.7 2.4 0.2 -0.6 0.2 -1.4 0.6 -0.2 0.3 -1.5
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 1.3 0.0 0.1 0.2 0.9 -1.1 0.6 -0.5 0.4
Ever unenthusiastic/disinterested for a whole week 1.5 1.9 5.4 -1.1 -0.0 -1.7 -0.5 2.1 -2.3 0.8 -0.2
Qualifications: None of the above 0.8 1.7 4.4 1.1 2.1 1.2 1.9 -0.7 0.4 -1.1 -1.1
Financial difficulties in last 2 years 2.2 3.0 5.0 1.7 1.7 2.1 2.2 -1.6 1.3 -2.1 -0.3
Mouth/teeth dental problems 1.5 2.2 6.4 -2.4 -0.1 -1.1 0.5 1.0 -1.2 1.4 2.5
Heart attack 0.2 0.3 0.8 -0.3 -0.9 0.2 -0.7 0.4 -0.5 -0.3 0.5
Allergy 1.6 3.7 7.2 -1.6 -0.6 -2.2 -0.0 2.7 -2.7 2.4 1.3
Pain all over the body in last month 0.9 1.0 2.5 0.3 1.0 1.4 1.6 -0.6 0.4 -1.0 1.1
Diabetes (self-reported) 1.2 1.8 3.3 1.5 1.2 1.8 0.8 -1.4 1.4 -1.8 -0.4
Hayfever/allergic rhinitis (self-reported) 1.7 2.3 4.3 1.2 0.4 1.9 0.0 -2.1 2.0 -1.6 -1.4
Medication: Ramipril 0.2 0.2 0.4 0.5 -0.6 0.2 -0.7 0.3 -0.0 0.2 -0.7
Medication: Simvastatin 0.1 0.2 0.5 0.3 0.7 -0.1 0.1 -0.4 0.5 -0.4 -0.5
Fluid intelligence score 0.1 0.2 0.5 0.5 0.0 0.2 -0.3 -0.7 0.5 -0.4 0.6
Illnesses of siblings 2.1 3.0 4.8 1.9 -0.3 1.6 -0.0 -2.2 2.2 -2.1 -1.9
Neuroticism score 0.2 0.4 1.4 0.1 -0.1 -0.4 -0.3 1.2 -1.1 0.1 -0.7
Weight 0.6 2.9 7.7 1.8 0.2 1.4 1.3 -1.8 1.3 -2.8 -2.0
Impedance of arm (right) 0.8 3.9 15.5 0.2 2.0 1.6 1.9 -1.6 1.3 -0.6 3.9
Arm fat percentage (right) 1.1 4.3 7.1 2.3 1.2 1.8 2.7 -2.5 2.0 -2.6 -0.3
Trunk fat-free mass 0.5 2.9 13.2 1.2 -1.1 0.5 -1.1 -0.6 0.4 -2.3 -3.6
Hip circumference 0.4 1.7 4.6 1.5 -0.1 1.2 0.9 -1.3 0.8 -2.1 -1.6
Time employed in main current job 0.9 1.0 2.9 -0.8 -1.7 -0.9 -1.7 0.5 -0.5 0.3 0.2
Alcohol intake versus 10 years previously 0.4 0.6 2.2 1.3 -0.6 -0.1 -0.9 -0.2 0.1 -0.2 -1.5
Father’s age at death 3.9 5.2 7.4 -1.1 -2.1 -2.5 -2.6 2.7 -2.5 2.7 1.5
Worrier / anxious feelings 2.1 3.9 7.5 -1.8 0.0 -2.2 -0.0 2.7 -2.7 2.6 1.4
Frequency of tiredness / lethargy in last 2 weeks 0.6 0.9 1.5 -0.6 -0.4 -1.0 -1.2 1.2 -1.1 0.7 -1.1
Falls in the last year 0.6 0.8 2.3 -1.5 1.4 -0.6 1.0 0.6 -0.8 -0.1 -0.1
Hair/balding pattern: Pattern 3 0.4 0.5 1.9 -1.2 -0.3 0.6 0.1 -0.3 0.2 -0.4 1.4
Number of live births 1.1 1.5 3.6 -1.6 -0.5 -1.3 -0.7 1.5 -1.9 0.7 0.8
Forced expiratory volume in 1-second (FEV1) 0.4 1.4 4.7 0.8 -1.4 0.2 -1.9 0.5 0.0 0.2 -2.2
Pulse rate 1.9 3.3 7.2 2.6 -0.6 2.7 -0.2 -1.8 2.3 -1.1 -1.7
Happiness 0.8 1.0 2.6 -0.6 -0.8 -0.7 -0.4 1.6 -1.4 1.1 0.6
Noisy workplace 0.8 0.9 3.5 1.0 1.0 0.8 0.7 -0.6 0.8 0.0 -1.9
Qualifications: A levels/AS levels or equivalent 1.1 2.4 4.4 -0.9 -1.9 -1.0 -2.1 1.7 -1.6 1.2 1.6
Serious illness, injury or assault of a close relative in last 2 years 1.0 1.1 2.5 -0.9 -0.5 -1.3 -1.6 1.1 -1.5 0.3 0.2
Mouth/teeth dental problems: Dentures 2.0 3.4 5.0 2.2 2.2 1.2 1.6 -2.0 1.5 -2.0 -1.6
Asthma 0.9 1.8 5.1 0.9 -0.5 0.2 -1.1 -1.8 1.5 -2.3 -1.1
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 2.5 -0.6 0.0 0.6 1.6 -0.4 -0.1 -0.7 1.1
Medication: Cholesterol lowering 0.1 0.1 0.5 0.6 0.7 0.0 -0.3 -0.2 0.1 -0.3 -0.2
Depression (self-reported) 0.4 0.4 1.7 0.9 1.3 0.3 -0.2 0.0 0.0 -0.5 -0.8
Medication: Lansoprazole 1.5 1.7 4.5 -0.4 2.0 1.2 2.1 -1.3 1.1 -0.8 0.7
Prospective memory result 0.2 0.2 0.6 -0.2 -0.2 0.2 -0.4 0.7 -0.4 -0.2 -0.8
Lung cancer (father) 0.8 0.9 2.6 -0.7 0.1 0.1 0.7 -1.6 1.1 -1.4 -0.7
Illnesses of mother 0.9 1.1 3.2 0.6 1.8 0.7 1.2 -0.9 1.0 -0.1 -1.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.7 6.1 0.8 -1.7 0.0 -2.5 0.8 -0.3 0.3 -1.8
Pulse wave Arterial Stiffness index 0.8 0.9 1.8 0.3 0.9 1.1 0.8 -1.2 1.3 -1.0 -0.2
Impedance of arm (left) 0.9 4.2 16.8 -0.0 2.2 1.4 2.2 -1.7 1.4 -0.2 4.1
Arm fat mass (right) 0.8 3.2 7.1 2.0 0.6 1.5 1.8 -2.0 1.5 -2.7 -1.5
Trunk predicted mass 0.5 2.9 13.0 1.3 -1.2 0.6 -1.0 -0.6 0.4 -2.3 -3.6
Standing height 0.1 1.4 6.1 0.1 0.2 1.1 -0.4 -1.5 1.1 -2.5 -0.0
Length of working week for main job 0.2 0.3 0.7 0.8 0.6 0.1 0.3 -0.1 0.1 0.5 0.8
Exposure to tobacco smoke at home 0.6 0.7 1.4 0.3 1.0 0.1 1.2 -0.6 0.4 -1.1 -1.1
Breastfed as a baby 1.1 1.4 5.7 -0.4 1.5 -0.0 1.7 0.0 0.1 0.7 2.4
Tense / ‘highly strung’ 0.1 0.2 0.6 -0.2 -0.7 -0.8 -0.7 0.5 -0.2 0.3 0.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.4 3.2 -1.2 0.9 -1.8 0.3 1.1 -1.3 1.0 1.5
Hair/balding pattern: Pattern 4 0.8 1.9 3.1 1.7 0.4 1.8 -0.1 -1.7 1.7 -1.5 -0.8
Birth weight of first child 0.6 1.1 2.7 -0.3 -0.9 -1.4 0.0 1.3 -1.2 1.6 0.5
Peak expiratory flow (PEF) 0.3 0.6 1.0 -1.0 -0.9 -0.8 -0.4 0.9 -1.0 0.5 0.1
Pulse wave reflection index 0.4 0.5 1.6 -1.2 0.8 -0.8 0.6 0.5 -0.6 0.2 0.5
Ever highly irritable/argumentative for 2 days 0.7 0.8 3.2 -0.9 1.2 0.3 1.8 0.6 -0.3 0.8 -0.2
Loud music exposure frequency 0.6 0.7 2.6 -0.2 -0.5 -0.3 -0.3 1.3 -0.9 1.6 0.3
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 0.9 0.1 -0.8 0.3 -1.0 -0.0 0.4 0.1 0.4
Mouth/teeth dental problems: Bleeding gums 1.7 2.2 3.1 1.7 -1.4 1.5 -1.6 -1.2 1.8 -1.0 -1.5
Blood clot in the leg (DVT) 0.7 0.9 1.8 -0.5 1.2 0.1 1.0 0.7 -0.5 1.4 1.3
Medication: Paracetamol 0.3 0.4 1.7 -0.3 0.4 -0.3 1.0 0.1 -0.5 0.4 1.3
Headache pain in last month 0.7 1.2 3.1 0.5 1.7 0.9 1.8 -1.1 0.6 -1.1 -0.4
Medication for cholesterol, blood pressure or diabetes 1.0 1.7 3.9 -2.0 -1.1 -1.4 0.3 1.3 -1.2 1.6 0.7
Glaucoma (self-reported) 0.4 0.5 1.4 -0.4 -1.0 -0.3 -0.9 0.4 -0.2 -0.0 -1.2
Gout (self-reported) 0.2 0.3 0.9 0.9 -0.1 0.2 -0.9 0.1 0.1 -0.1 -0.6
Hypothyroidism/myxoedema (self-reported) 1.2 2.4 5.6 0.6 0.5 2.2 0.5 -2.2 2.4 -1.6 -0.8
Medication: Amlodipine 1.4 1.9 7.0 1.3 2.6 0.9 2.1 -0.9 0.7 -0.5 -0.2
Medication: Ventolin 100micrograms inhaler 0.4 0.5 1.6 0.2 -0.9 -0.5 -1.3 0.2 -0.0 -0.2 -1.0
Birth weight 0.3 0.7 1.7 -0.0 -1.1 -0.8 -0.1 0.9 -0.5 1.3 1.0
Chronic bronchitis/emphysema (mother) 0.2 0.3 0.5 0.7 0.7 -0.3 -0.1 0.3 -0.5 -0.7 0.6
High blood pressure (siblings) 1.8 2.6 4.0 -1.7 -0.3 -1.5 -1.1 1.9 -1.8 2.0 1.7
Forced vital capacity (FVC), Best measure 0.3 1.2 4.7 0.2 -1.0 -0.4 -2.2 1.2 -0.9 0.7 -1.0
Body fat percentage 0.8 3.1 8.0 1.6 1.3 1.4 2.8 -2.1 1.6 -1.9 0.4
Leg fat percentage (right) 0.6 2.1 7.7 0.7 1.3 0.8 2.8 -1.6 0.9 -1.6 0.4
Arm fat-free mass (right) 0.4 2.1 11.3 0.6 -1.2 0.0 -0.9 -0.2 -0.1 -1.7 -3.4
Exposure to tobacco smoke outside home 6.3 8.4 17.1 4.1 2.6 3.0 1.4 -3.3 3.3 -2.9 -1.5
Comparative body size at age 10 0.6 1.7 5.7 2.4 -0.8 0.7 -1.2 -0.1 0.8 -0.3 -2.0
Number of full brothers 0.6 0.8 2.7 -0.4 1.6 0.4 1.1 -0.9 0.8 -0.6 -0.0
Worry too long after embarrassment 0.3 0.5 1.3 -0.3 -0.0 -0.8 -0.6 1.1 -1.1 0.2 -0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 1.1 1.0 0.8 0.6 -0.2 -0.7 0.8 -0.6 -0.2
Wheeze or whistling in the chest in last year 1.0 1.8 6.7 -0.4 -2.6 -0.9 -2.5 0.3 -0.4 0.6 0.1
Number of children fathered 0.7 0.8 2.0 -0.7 -0.4 -1.3 -0.0 0.5 -0.5 1.4 1.1
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 1.0 -0.1 -0.0 -0.3 -1.0 0.4 -0.2 0.7 0.1
Age at first live birth 1.8 3.2 7.4 -0.7 -2.7 -1.5 -2.4 1.7 -1.4 1.6 1.3
Pulse wave peak to peak time 0.5 0.6 1.2 -0.0 -0.8 -1.0 -1.0 1.0 -1.1 0.6 -0.1
Health satisfaction 0.3 0.3 1.0 0.4 0.6 -0.7 0.4 0.6 -1.0 -0.2 -0.1
Shortness of breath walking on level ground 0.2 0.3 0.6 -0.6 -0.6 -0.4 0.0 0.6 -0.8 0.5 -0.3
Qualifications: College or University degree 0.8 2.4 5.7 -0.4 -2.4 -1.0 -2.2 1.7 -1.5 1.5 0.2
Eye problems/disorders: None of the above 0.5 0.6 2.3 0.5 -1.5 -0.1 -0.8 0.1 0.5 1.0 0.2
Mouth/teeth dental problems: Loose teeth 1.2 1.4 4.3 -1.4 -2.1 -1.2 -0.8 0.9 -0.9 1.0 0.6
Emphysema/chronic bronchitis 0.3 0.3 1.2 1.1 0.0 0.7 0.2 -0.6 0.5 -0.5 0.2
Medication for pain relief, constipation, heartburn 0.7 1.2 3.4 -0.2 -0.6 -1.0 -1.8 1.3 -0.6 1.2 -1.2
Neck or shoulder pain in last month 2.1 2.9 5.8 -0.5 -1.4 -2.1 -1.7 2.4 -2.0 1.9 -0.6
Medication: Blood pressure 1.5 2.6 5.2 2.3 1.0 1.9 -0.4 -2.0 2.0 -1.7 -0.3
Angina (self-reported) 2.9 3.8 6.1 -1.5 -1.9 -1.8 -1.4 2.4 -2.5 2.2 1.5
Migraine (self-reported) 1.2 1.5 3.6 0.5 1.5 1.9 1.3 -1.0 1.2 -1.1 0.5
Medication: Ibuprofen 0.5 0.6 3.2 -0.5 -0.0 0.5 1.8 -0.2 -0.3 -0.7 0.4
Medication: Allopurinol 0.3 0.3 1.1 -0.1 -0.2 -0.8 -1.0 0.6 -0.7 0.3 -0.3
Medication: Omeprazole 0.9 1.0 3.3 -0.1 -0.9 -1.2 -0.1 0.9 -1.2 0.7 1.8
Medication: Seretide 50 evohaler 0.3 0.3 0.6 -0.6 0.2 -0.3 -0.8 0.8 -0.7 0.7 0.2
Mean time to correctly identify matches 0.5 0.9 4.6 2.1 -0.8 -0.3 -1.3 -0.1 0.5 0.5 0.1
Heart disease (mother) 0.2 0.2 1.3 -0.1 -0.5 0.2 0.3 -0.1 0.0 -0.3 1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 1.8 0.0 -1.1 -0.1 -0.8 -0.6 0.3 -1.1 1.4
Whole body fat mass 0.7 3.0 6.4 1.6 0.7 1.5 2.2 -2.1 1.5 -2.5 -0.7
Leg fat mass (right) 0.5 1.9 5.2 1.1 0.4 0.9 1.8 -1.6 0.9 -2.3 -1.0
Arm predicted mass (right) 0.4 2.3 11.8 0.8 -1.5 -0.1 -1.1 0.0 -0.1 -1.6 -3.4
Pulse rate, automated reading 1.0 3.1 7.3 2.5 0.0 2.3 0.4 -2.2 2.7 -1.0 -0.5
Alcohol intake frequency. 1.2 2.7 4.4 1.5 2.1 1.6 1.2 -1.9 1.6 -2.1 -0.7
Comparative height size at age 10 0.2 1.2 3.9 -0.2 -1.9 -0.7 -2.0 0.8 -0.7 -0.2 -0.9
Number of full sisters 0.7 0.9 2.9 -1.2 1.7 0.4 1.2 -0.4 0.2 -0.6 0.6
Suffer from ‘nerves’ 0.2 0.3 1.0 0.3 -0.4 -0.0 -0.7 -0.3 0.3 -1.0 -0.4
Overall health rating 0.2 0.4 0.8 0.9 -0.2 -0.7 -0.3 0.6 -0.9 -0.4 -0.9
Chest pain or discomfort 1.2 1.7 5.0 -2.2 -1.6 -1.0 -0.9 1.1 -0.9 1.4 0.7
Had major operations 1.1 1.3 4.0 -1.0 -1.6 -0.4 -2.0 1.2 -0.9 0.2 -0.4
Age at last live birth 2.3 3.3 9.7 -1.2 -3.1 -1.6 -2.3 1.8 -1.7 1.2 0.4
Family relationship satisfaction 0.1 0.2 0.7 0.3 -0.2 0.9 0.5 -0.1 0.2 -0.3 -0.0
Leg pain on walking 0.7 0.9 4.9 0.7 -0.4 -0.0 0.2 1.1 -0.6 0.5 -2.2
Qualifications: NVQ or HND or HNC or equivalent 1.5 1.8 6.3 -0.8 -0.2 -1.2 0.1 1.3 -1.4 1.6 2.5
Commuting to job workplace: Car/motor vehicle 0.9 1.0 2.3 -0.6 0.2 -1.1 0.1 1.2 -1.3 1.5 1.1
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 2.6 -0.2 0.8 0.8 1.6 -0.8 0.8 -0.2 -0.0
Medication: Aspirin 1.8 2.4 5.6 0.6 0.7 2.0 0.8 -2.1 1.9 -2.4 0.2
Supplements: Vitamin C 5.9 7.0 11.4 -1.4 -3.4 -2.4 -2.1 2.8 -2.7 2.5 3.2
Knee pain experienced in last month 1.5 2.3 7.7 1.5 -1.6 -0.2 -2.0 -0.7 0.7 -0.9 -2.8
Hypertension (Self-reported) 0.7 2.0 4.0 1.6 1.2 0.6 1.3 -2.0 1.3 -2.0 -0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 2.6 -0.9 -0.4 -0.1 0.9 -0.4 0.1 -0.1 1.6
Illnesses of father: Heart disease 1.3 1.7 3.5 1.9 1.0 1.4 1.2 -1.5 1.7 -0.9 -0.4
Illnesses of siblings: Diabetes 0.2 0.3 0.9 -0.2 0.9 0.4 0.9 0.1 0.1 0.3 0.5
Smoking status: Previous 1.1 1.6 2.7 -0.0 1.6 1.1 1.7 -1.5 1.4 -0.8 1.0
Forced expiratory volume in 1-second (FEV1), predicted 0.7 1.4 3.6 1.0 0.1 1.9 0.1 -1.3 1.4 -1.5 -0.7
Whole body fat-free mass 0.6 3.3 13.8 1.6 -1.3 0.7 -1.0 -0.7 0.6 -2.4 -3.7
Leg fat-free mass (right) 0.6 3.2 12.8 1.7 -1.6 0.7 -1.1 -0.7 0.5 -2.2 -3.6
Arm fat percentage (left) 1.1 4.6 8.6 2.3 1.4 1.9 2.9 -2.6 2.1 -2.5 -0.3
Average weekly red wine intake 0.6 0.9 3.2 0.8 -1.3 -0.4 -1.8 -0.2 0.7 0.6 0.8
Handedness (chirality/laterality): Left-handed 0.7 0.8 2.1 0.9 -0.9 -0.1 -1.5 0.3 0.3 0.8 -1.4
Mood swings 0.9 1.6 5.7 2.0 0.4 0.6 -0.4 -0.7 0.9 -0.9 -2.4
Loneliness, isolation 0.6 0.8 3.3 0.2 0.8 0.6 0.3 -0.6 0.4 -1.3 -1.8
Long-standing illness, disability or infirmity 0.5 0.7 1.6 1.2 -0.3 0.5 -0.9 -0.6 0.5 -1.3 -1.0
Ever had bowel cancer screening 0.1 0.2 0.5 0.7 0.2 0.1 -0.6 -0.1 0.1 -0.6 -0.3
Diabetes diagnosed by doctor 0.8 1.3 4.0 1.1 0.7 1.3 0.4 -1.3 1.1 -2.0 -0.2
Ever had stillbirth, spontaneous miscarriage or termination 1.4 1.5 3.7 -0.5 1.4 1.6 1.9 -0.9 0.9 -0.7 1.3
Friendships satisfaction 0.1 0.1 0.3 -0.3 0.0 0.6 0.3 0.5 -0.4 0.2 0.1
Qualifications: nursing, teaching 0.5 0.8 1.9 0.0 -0.6 -0.7 -0.8 1.1 -0.7 1.4 1.1
Commuting to job workplace: Walk 0.3 0.3 0.8 0.4 0.7 0.5 0.1 0.6 -0.6 -0.3 0.9
Eye problems/disorders: Cataract 0.5 0.6 1.6 -0.6 1.2 -0.6 -0.2 0.8 -1.3 -0.0 0.5
Mouth/teeth dental problems: Mouth ulcers 0.6 1.0 3.0 1.2 0.3 1.7 -0.1 -0.8 1.1 -0.9 -0.9
Medication for cholesterol 0.2 0.2 1.4 -0.1 -0.2 0.6 -0.0 -0.1 0.1 -0.1 1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.1 2.9 1.7 1.3 0.5 0.6 -1.2 1.0 -1.1 0.1
Back pain experienced in last month 0.8 1.2 2.6 -0.6 -0.6 -1.3 0.1 1.5 -1.6 0.9 -1.0
Mineral and other dietary supplements 1.3 1.8 5.6 0.1 2.4 1.3 2.2 -1.0 0.8 -0.8 -0.2
Breast cancer (self-reported) 2.3 2.8 4.5 -1.7 -2.1 -1.2 -2.0 2.1 -2.1 0.7 0.3
Asthma (self-reported) 1.2 2.4 6.6 1.1 -0.4 0.6 -1.1 -2.1 1.8 -2.6 -1.4
Osteoporosis (self-reported) 2.2 2.8 5.4 -0.3 -1.6 -1.6 -2.3 2.1 -1.8 1.4 -1.3
Osteoarthritis (self-reported) 1.6 2.1 5.9 -1.2 0.1 -2.4 -0.4 1.9 -2.2 0.8 0.2
Medication: Aspirin 2.2 2.9 5.8 0.7 1.1 2.1 1.1 -2.4 2.2 -2.4 0.1
Medication: Gliclazide 0.4 0.5 1.0 -0.4 0.8 0.1 0.8 -1.0 0.7 -0.6 0.7
Illnesses of father: None of the above (group 1) 0.3 0.3 1.1 0.2 0.8 0.2 1.0 -0.6 0.4 -0.3 -0.6
Smoking status: Current 0.8 1.2 3.2 1.8 0.8 0.5 1.0 -0.6 0.4 -1.1 -1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.4 3.0 7.1 -0.9 -2.3 -0.9 -2.7 2.2 -1.9 1.4 -0.2
Whole body water mass 0.6 3.2 14.0 1.5 -1.4 0.5 -1.1 -0.6 0.4 -2.3 -3.7
Leg predicted mass (right) 0.6 3.1 12.4 1.8 -1.5 0.8 -1.0 -0.7 0.5 -2.2 -3.5
Arm fat mass (left) 0.9 3.7 7.0 2.2 0.8 1.6 2.2 -2.2 1.7 -2.6 -1.4
Number of self-reported non-cancer illnesses 0.7 1.2 5.1 0.8 0.3 -0.0 -0.5 -1.0 0.8 -1.3 -2.3
Average weekly champagne plus white wine intake 0.7 1.0 3.3 -1.8 -0.1 0.4 0.8 0.0 0.2 0.6 1.7
Miserableness 1.0 1.7 4.4 2.1 1.3 0.8 0.4 -0.5 0.3 -1.6 -2.0
Guilty feelings 0.7 1.0 2.1 -1.4 0.8 -0.5 0.4 1.4 -1.4 0.9 -0.6
Wears glasses or contact lenses 0.5 0.6 1.6 0.9 -1.3 0.5 -0.9 0.5 -0.5 0.0 -1.0
Ever taken oral contraceptive pill 3.7 4.1 7.1 2.1 1.5 2.6 1.6 -2.3 2.2 -2.7 0.3
Hearing aid user 0.2 0.3 0.5 -0.6 0.4 -0.7 -0.3 0.6 -0.5 0.2 0.7
Mother’s age at death 0.3 0.4 1.8 0.6 -0.2 -0.4 -0.2 0.4 -0.4 0.6 1.4
Financial situation satisfaction 1.4 1.7 6.0 -0.1 1.9 1.1 2.5 -1.0 0.8 -1.0 0.5
Tinnitus: Yes, now most or all of the time 1.1 1.3 2.5 -0.5 -1.4 -1.2 -1.3 1.6 -1.4 0.7 0.1
Commuting to job workplace: Public transport 1.1 1.3 3.4 0.9 -0.1 1.8 -0.5 -1.1 1.4 -1.5 -0.5
Eye problems/disorders: Glaucoma 0.5 0.5 0.8 -0.8 -0.9 -0.8 -0.8 0.7 -0.9 -0.1 -0.6
Medication: Blood pressure 0.1 0.3 0.7 0.2 -0.4 -0.1 0.6 -0.6 0.4 -0.6 -0.8
Pain type(s) experienced in last month: Hip pain 4.0 5.0 9.8 -1.9 -1.6 -3.1 -1.6 2.8 -2.8 2.3 -0.8
Supplements: Fish oil (including cod liver oil) 0.2 0.3 0.8 0.5 -0.8 -0.1 -0.9 -0.1 0.3 0.1 -0.5
High cholesterol (Self-reported) 0.4 0.7 3.4 0.6 0.8 -0.3 0.3 0.2 -0.3 -0.7 -1.9
Medication: Bendroflumethiazide 0.8 1.3 2.2 1.3 0.7 1.2 0.6 -1.5 1.4 -1.3 -0.7
Medication: Paracetamol 0.5 0.8 3.5 -0.2 1.4 -0.0 1.9 -0.3 -0.2 -0.2 0.8
Medication: Lisinopril 0.4 0.5 1.8 0.3 -0.9 -0.3 -1.3 -0.7 0.7 -0.5 0.1
Medication: Atorvastatin 1.4 1.7 2.7 1.2 -1.4 -1.0 -1.7 1.6 -1.6 0.2 -1.1
Illnesses of father: High blood pressure 1.4 1.7 2.7 1.4 -0.7 1.1 -0.7 -1.6 1.6 -1.5 -1.6
Alcohol drinker status: Never 0.8 1.0 3.8 0.2 1.9 1.0 1.0 -0.6 0.3 -1.1 0.4
Ever smoked 1.6 2.9 6.8 0.7 1.7 1.9 2.6 -2.0 1.9 -1.0 0.6
Basal metabolic rate 0.6 3.1 11.6 1.6 -1.0 0.8 -0.5 -1.0 0.7 -2.6 -3.4
Leg fat percentage (left) 0.3 1.3 6.2 0.7 0.9 0.5 2.5 -1.0 0.5 -1.0 0.2
Arm fat-free mass (left) 0.5 2.4 11.4 1.0 -1.4 0.1 -1.1 -0.2 -0.1 -1.9 -3.4
Number of operations (self-reported) 0.6 0.9 2.1 -1.0 0.6 -0.7 0.1 1.2 -1.5 0.7 1.3
Average weekly beer plus cider intake 0.5 0.7 3.3 0.9 1.2 0.2 1.8 -0.1 0.0 -0.0 0.3
Irritability 0.2 0.4 1.1 -0.2 1.0 0.4 0.7 0.4 -0.3 0.7 0.8
Risk taking 0.5 0.7 2.2 1.1 -0.1 0.5 0.4 -0.9 0.5 -1.5 -0.9
Ever had prostate specific antigen (PSA) test 0.8 1.0 3.4 0.0 0.4 -1.1 -1.2 0.9 -0.7 1.8 0.6
Fractured/broken bones in last 5 years 1.1 1.4 2.3 -1.3 1.2 -0.9 0.6 1.5 -1.4 1.4 0.4
Age started oral contraceptive pill 1.8 2.2 3.9 -1.4 -1.9 -2.0 -1.5 1.3 -1.8 0.5 1.0
Diastolic blood pressure, automated reading 0.6 1.8 3.8 1.9 0.7 1.0 0.6 -2.0 1.7 -1.0 -1.0
Ever depressed for a whole week 0.8 1.0 2.6 -1.1 0.5 -1.3 -0.3 1.1 -1.6 -0.1 -0.7
Unable to work because of sickness or disability 0.1 0.1 0.5 -0.2 0.5 0.4 0.2 -0.0 0.1 0.2 -0.7
Commuting to job workplace: Cycle 0.4 0.5 2.9 0.6 -0.0 0.2 0.1 -0.2 0.1 -0.8 -1.7
Myopia 0.2 0.3 0.7 0.9 -0.6 0.4 -0.9 -0.0 0.1 -0.3 0.2
Vascular/heart problems diagnosed by doctor 0.3 0.8 2.0 -1.2 -0.7 -0.2 -0.7 1.4 -0.7 1.3 0.3
Cholesterol lowering medication 0.3 0.4 1.0 -0.7 0.0 -1.0 0.3 1.0 -1.0 0.3 0.3
Medication: Omeprazole (e.g. Zanprol) 1.1 1.3 3.6 -0.3 -1.6 -1.0 -0.5 1.0 -1.1 0.7 1.9
Pain experienced in last month 1.1 1.9 3.5 -0.0 1.7 1.6 1.8 -1.5 1.9 -0.4 0.6
Supplements: Calcium 1.3 1.4 2.4 -1.4 -0.3 -1.6 -0.0 1.4 -1.5 1.4 0.9
Basal cell carcinoma (self-reported) 0.5 0.6 1.5 -0.6 -1.0 0.4 -0.2 -1.0 0.7 -1.2 0.6
Heart attack/myocardial infarction (self-reported) 0.3 0.4 1.2 -0.3 -1.1 0.1 -0.9 0.5 -0.6 -0.2 0.2
Deep venous thrombosis (DVT) (self-reported) 0.8 1.0 2.2 -0.4 1.3 0.0 0.9 0.8 -0.6 1.4 1.5
Heart disease (siblings) 0.3 0.4 1.0 -0.1 0.4 -1.0 -0.0 0.6 -0.9 0.8 0.3
Alcohol drinker status: Previous 0.5 0.5 1.0 1.0 -0.1 1.0 0.1 -0.8 1.0 0.2 0.8
Pack years of smoking 0.6 0.8 3.2 1.8 0.3 1.4 0.4 -0.4 0.5 -0.8 -0.4
Impedance of whole body 0.9 4.6 21.1 -0.9 2.5 0.9 2.2 -1.3 1.0 0.2 4.6
Leg fat mass (left) 0.3 1.2 3.6 1.1 -0.0 0.5 1.4 -1.1 0.5 -1.9 -1.2
Arm predicted mass (left) 0.5 2.5 12.0 0.9 -1.6 -0.2 -1.2 0.0 -0.3 -1.8 -3.5