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chr2:101,922,170-104,027,106

Best TWAS P=4.84e-85 · Best GWAS P=1.15e-77 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	IL1R1	0.14	0.09	lasso	3	0.10	4.0e-12	-6.34	6.5	7.3e-11	-0.15	1.00	0.00	TRUE
2	CommonMind	Brain Pre-frontal Cortex	IL1RL2	0.18	0.05	bslmm	549	0.09	1.8e-11	-10.61	-6.1	8.4e-10	0.26	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	SLC9A2	0.17	0.10	lasso	4	0.11	4.7e-13	5.44	5.7	1.3e-08	-0.23	1.00	0.00	TRUE
4	GTEx	Colon Transverse	IL18R1	0.14	0.00	enet	41	0.00	2.1e-01	1.90	11.4	3.7e-30	-0.40	0.04	0.48	FALSE
5	GTEx	Lung	IL18R1	0.06	0.01	lasso	4	0.02	1.2e-02	-1.45	6.0	1.9e-09	-0.58	0.20	0.45	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	IL1R2	0.29	0.17	lasso	7	0.13	1.7e-07	4.64	5.6	1.9e-08	-0.19	0.99	0.00	TRUE
7	GTEx	Whole Blood	IL18R1	0.06	0.00	enet	14	0.01	2.1e-02	-14.88	8.4	4.1e-17	-0.24	0.17	0.05	FALSE
8	GTEx	Whole Blood	IL18RAP	0.14	0.18	lasso	10	0.18	6.0e-16	3.99	-5.2	1.8e-07	0.23	1.00	0.00	TRUE
9	NTR	Blood	IL18R1	0.05	0.02	bslmm	582	0.02	5.1e-07	5.03	7.1	1.1e-12	-0.29	0.99	0.00	FALSE
10	NTR	Blood	IL18RAP	0.14	0.16	lasso	7	0.19	1.1e-59	11.67	-8.1	5.4e-16	0.26	1.00	0.00	TRUE
11	ROSMAP	Brain Pre-frontal Cortex	IL1RL2	0.08	0.02	enet	33	0.03	2.3e-04	6.36	-11.7	1.7e-31	0.48	0.17	0.18	FALSE
12	YFS	Blood	IL18RAP	0.41	0.55	bslmm	562	0.62	4.2e-269	11.67	-9.3	1.4e-20	0.32	1.00	0.00	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	IL1RL1	0.04	0.03	lasso	7	0.03	8.1e-04	-14.88	-14.8	2.0e-49	0.50	0.24	0.12	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	IL18R1	0.05	0.01	blup	108	0.03	1.8e-07	-14.86	8.6	6.3e-18	-0.08	0.99	0.00	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	IL1RL1	0.02	0.01	blup	78	0.01	1.5e-03	11.50	-15.3	1.3e-52	0.63	0.16	0.22	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IL1RL1	0.04	0.04	lasso	8	0.04	1.7e-05	-18.52	-19.5	4.8e-85	0.91	0.01	0.99	TRUE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL18R1	0.06	0.01	blup	108	0.04	2.6e-05	-0.33	-8.3	1.1e-16	0.63	0.01	0.86	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL18RAP	0.03	0.02	blup	94	0.02	1.2e-03	-14.86	15.8	4.5e-56	-0.61	0.01	0.82	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL1RL1	0.08	0.08	enet	9	0.08	1.2e-09	-18.61	-19.4	8.3e-84	0.95	0.00	1.00	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL1RL2	0.04	0.04	enet	5	0.03	1.9e-04	-14.04	-14.8	2.9e-49	0.70	0.06	0.41	FALSE
21	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	IL1RL1	0.18	0.06	blup	78	0.15	3.7e-09	11.50	-17.8	5.4e-71	0.83	0.02	0.98	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	IL18R1	0.25	0.29	blup	108	0.31	1.6e-35	-1.45	7.0	3.7e-12	-0.62	1.00	0.00	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	IL1RL1	0.03	0.01	blup	78	0.02	4.7e-03	-18.02	-18.7	4.5e-78	0.84	0.01	0.94	FALSE
24	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	IL1R2	0.20	0.03	enet	14	0.04	1.7e-03	4.86	5.2	1.8e-07	-0.21	0.04	0.04	FALSE
25	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	IL1RL1	0.19	0.05	blup	78	0.10	7.1e-05	11.55	-16.6	1.1e-61	0.62	0.11	0.72	TRUE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	IL1R1	0.36	0.19	enet	28	0.23	1.1e-23	-12.93	10.8	4.7e-27	-0.51	0.58	0.42	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	IL1RL1	0.05	0.03	enet	6	0.03	9.7e-04	-18.61	-18.8	3.4e-79	0.98	0.00	0.99	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	SLC9A2	0.05	0.01	blup	93	0.02	8.6e-03	5.18	5.8	5.9e-09	-0.17	0.10	0.04	TRUE