[Hub]/) : Traits : Lung FVC : ← →

chr17:72,503,355-74,267,010

Best TWAS P=3.65e-12 · Best GWAS P=7.97e-12 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	LLGL2	0.07	0.01	blup	364	0.03	2.7e-04	6.8	5.7	1.0e-08	0.73	0.00	1.00	FALSE
2	GTEx	Adipose Subcutaneous	GGA3	0.08	0.03	lasso	4	0.03	2.0e-03	4.7	5.2	1.6e-07	0.53	0.12	0.79	FALSE
3	GTEx	Brain Cerebellar Hemisphere	GGA3	0.22	0.00	lasso	4	0.00	3.0e-01	5.2	6.8	8.8e-12	0.60	0.04	0.35	FALSE
4	GTEx	Colon Transverse	GGA3	0.27	0.08	lasso	3	0.08	1.1e-04	4.7	5.3	1.3e-07	0.43	0.70	0.03	FALSE
5	GTEx	Colon Transverse	NUP85	0.33	0.18	enet	26	0.23	2.0e-11	3.8	5.6	2.1e-08	0.51	1.00	0.00	FALSE
6	GTEx	Esophagus Mucosa	TSEN54	0.12	0.00	lasso	5	0.00	3.0e-01	5.4	-6.8	1.1e-11	-0.45	0.10	0.32	FALSE
7	GTEx	Esophagus Muscularis	LLGL2	0.23	0.17	lasso	4	0.17	2.0e-10	6.3	6.5	8.2e-11	0.25	0.08	0.92	FALSE
8	GTEx	Heart Left Ventricle	LLGL2	0.23	0.09	lasso	5	0.11	2.5e-06	6.3	7.0	3.6e-12	0.36	0.08	0.90	TRUE
9	GTEx	Heart Left Ventricle	MRPS7	0.17	0.13	enet	16	0.13	1.3e-07	4.7	-5.2	2.0e-07	-0.43	0.94	0.04	TRUE
10	GTEx	Muscle Skeletal	LLGL2	0.22	0.08	lasso	8	0.08	4.3e-08	6.3	6.7	2.1e-11	0.30	0.10	0.90	FALSE
11	GTEx	Nerve Tibial	MIF4GD	0.09	0.01	enet	12	0.02	6.9e-03	2.9	-6.0	2.0e-09	-0.33	0.12	0.41	TRUE
12	GTEx	Spleen	MRPS7	0.24	0.17	lasso	4	0.16	6.4e-05	4.7	-5.3	8.7e-08	-0.45	0.15	0.06	FALSE
13	GTEx	Stomach	GGA3	0.15	0.03	lasso	8	0.07	4.6e-04	4.7	5.5	3.8e-08	0.38	0.33	0.21	TRUE
14	GTEx	Testis	LLGL2	0.17	0.05	enet	15	0.13	2.4e-06	1.8	-6.8	8.1e-12	-0.59	0.14	0.62	FALSE
15	GTEx	Testis	TSEN54	0.50	0.34	enet	15	0.31	2.1e-14	5.5	5.2	1.8e-07	0.04	0.92	0.08	FALSE
16	GTEx	Thyroid	LLGL2	0.08	0.04	lasso	3	0.04	4.7e-04	6.2	5.3	1.2e-07	0.14	0.06	0.34	FALSE
17	GTEx	Whole Blood	MIF4GD	0.07	0.06	lasso	4	0.04	1.2e-04	5.7	-5.5	3.7e-08	-0.51	0.31	0.60	FALSE
18	METSIM	Adipose	GGA3	0.06	0.03	blup	374	0.06	8.8e-09	4.8	5.9	4.2e-09	0.63	0.26	0.74	FALSE
19	YFS	Blood	KIAA0195	0.06	0.05	enet	22	0.07	2.3e-22	1.9	5.5	5.2e-08	0.42	0.95	0.05	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	GRB2	0.02	0.00	blup	43	0.01	4.6e-03	6.8	5.7	9.3e-09	0.88	0.01	0.89	FALSE
21	The Cancer Genome Atlas	Breast Invasive Carcinoma	MIF4GD	0.01	0.00	blup	28	0.01	6.0e-03	4.7	-5.8	4.8e-09	-0.64	0.02	0.47	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MRPS7	0.04	0.05	enet	6	0.06	7.8e-07	4.7	-5.1	2.8e-07	-0.61	0.45	0.50	FALSE
23	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SLC25A19	0.12	0.16	enet	8	0.18	8.0e-09	5.4	-5.8	6.2e-09	-0.59	0.10	0.90	FALSE
24	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	MRPS7	0.13	0.08	lasso	3	0.09	8.8e-05	4.7	-5.1	2.7e-07	-0.58	0.28	0.54	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	MRPS7	0.08	0.08	blup	27	0.09	1.8e-09	4.7	-5.4	8.2e-08	-0.58	0.78	0.21	TRUE
26	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	NUP85	0.10	0.02	blup	26	0.03	5.4e-02	4.7	5.4	8.4e-08	0.54	0.01	0.59	TRUE